MCID: PRD007
MIFTS: 66

Periodontal Disease

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Periodontal Disease

MalaCards integrated aliases for Periodontal Disease:

Name: Periodontal Disease 12 77 15
Periodontal Diseases 56 45 74
Disease of Supporting Structures of Teeth 12
Periodontium Disorder 12
Gingival Diseases 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3388
MeSH 45 D010510
NCIt 51 C63743
SNOMED-CT 69 13877006 2556008
ICD10 34 K05.6 K08 K08.8

Summaries for Periodontal Disease

MalaCards based summary : Periodontal Disease, also known as periodontal diseases, is related to periodontosis and gingivitis, and has symptoms including snoring, halitosis and oral manifestations. An important gene associated with Periodontal Disease is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are PEDF Induced Signaling and Innate Immune System. The drugs Metronidazole and Levonorgestrel have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and heart, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 77 Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the... more...

Related Diseases for Periodontal Disease

Diseases related to Periodontal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 521)
# Related Disease Score Top Affiliating Genes
1 periodontosis 32.5 CXCL8 ELANE MMP9 TLR4 TNF TNFSF11
2 gingivitis 31.8 CXCL8 ELANE GUSB IL1A IL1B IL6
3 aggressive periodontitis 31.7 CTSC CXCL8 IL1A IL1B IL6 MMP1
4 bone resorption disease 31.2 IL6 TNFRSF11B TNFSF11
5 heart disease 31.1 CRP CXCL8 IL1B IL6 TNF
6 periodontitis, chronic 30.9 IL1B IL6 MMP1 MMP8 TLR2 TNFRSF11B
7 osteoporosis 30.6 IL1A IL1B IL6 TNF TNFRSF11B TNFSF11
8 arteries, anomalies of 30.6 CRP IL1B IL6 MMP9 TNF
9 atherosclerosis susceptibility 30.6 CRP IL6 TLR4 TNF
10 arthritis 30.5 CXCL8 IL17A IL1A IL1B IL6 MMP1
11 familial mediterranean fever 30.5 CRP IL1B TNF
12 apnea, obstructive sleep 30.5 CRP IL6 TNF
13 sleep apnea 30.3 CRP CXCL8 IL1B IL6 TNF
14 acquired immunodeficiency syndrome 30.3 IL1B IL6 TNF
15 root resorption 30.3 IL1A IL1B TNFRSF11B TNFSF11
16 ischemic heart disease 30.2 CRP IL6 TNF
17 endocarditis 30.2 CRP CXCL8 IL6 TLR2 TNF
18 osteoporotic fracture 30.2 IL6 TNFRSF11B
19 crohn's colitis 30.2 CXCL8 IL1B TNF
20 duodenal ulcer 30.2 CXCL8 IL1B TNF
21 periodontitis 30.2 CRP CTSC CXCL8 IL17A IL1A IL1B
22 placenta disease 30.2 CXCL8 IL1B IL6
23 pyoderma 30.1 CXCL8 MMP9 TNF
24 bacterial vaginosis 30.1 CXCL8 IL1A IL1B IL6 TLR2 TLR4
25 myocardial infarction 30.1 CRP IL1B IL6 MMP2 MMP9 TIMP1
26 cerebral palsy 30.1 IL1B IL6 MMP8 TNF
27 prostatitis 30.0 CXCL8 IL1B IL6 TNF
28 aphthous stomatitis 30.0 IL1B IL6 TLR2 TNF
29 autoimmune disease 30.0 IL17A IL1B IL6 TNF
30 infective endocarditis 29.9 CRP IL6 TLR2 TNF
31 vascular disease 29.9 CRP ELANE IL6 MMP9 TNF TNFRSF11B
32 bacterial pneumonia 29.9 CRP CXCL8 ELANE IL17A IL6 TLR4
33 juvenile rheumatoid arthritis 29.9 CRP IL1B IL6 TNF
34 cytomegalovirus infection 29.9 CXCL8 IL1B IL6 TNF
35 spondylitis 29.8 CRP IL17A IL6 TNF
36 periapical periodontitis 29.8 IL1B IL6 MMP8 TLR2 TNF TNFRSF11B
37 brucellosis 29.8 CRP CXCL8 IL6 TLR4 TNF
38 inflammatory bowel disease 29.8 CRP CXCL8 IL17A IL1B IL6 TLR2
39 cerebrovascular disease 29.8 CRP IL6 MMP9 TLR4 TNF
40 colitis 29.7 CXCL8 IL17A IL1B IL6 TLR4 TNF
41 spondyloarthropathy 1 29.7 CRP IL17A TLR4 TNF TNFRSF11B
42 pneumonia 29.7 CRP CXCL8 ELANE IL1B IL6 TLR2
43 systemic lupus erythematosus 29.7 CRP ELANE IL17A IL1B IL6 TLR2
44 gingival overgrowth 29.6 IL1A IL6 MMP1 MMP2 TIMP1
45 pulmonary emphysema 29.6 ELANE MMP1 MMP8 MMP9 TIMP1
46 ulcerative colitis 29.6 CRP CXCL8 IL17A IL1B IL6 TLR4
47 pulmonary disease, chronic obstructive 29.5 CRP CXCL8 ELANE IL17A IL6 MMP1
48 rheumatoid arthritis 29.5 CRP CXCL8 IL17A IL1A IL1B IL6
49 chlamydia 29.4 CRP CXCL8 IL1A IL1B IL6 TLR2
50 asthma 29.3 CXCL8 ELANE IL17A IL1A IL1B IL6

Graphical network of the top 20 diseases related to Periodontal Disease:



Diseases related to Periodontal Disease

Symptoms & Phenotypes for Periodontal Disease

UMLS symptoms related to Periodontal Disease:


snoring, halitosis, oral manifestations, tenderness of gums

MGI Mouse Phenotypes related to Periodontal Disease:

47 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.36 CRP CTSC ELANE GUSB IL17A IL1A
2 hematopoietic system MP:0005397 10.33 CTSC ELANE GUSB IL17A IL1A IL1B
3 immune system MP:0005387 10.33 CRP CTSC ELANE IL17A IL1A IL1B
4 growth/size/body region MP:0005378 10.29 CTSC GUSB IL17A IL1B IL6 MMP2
5 cardiovascular system MP:0005385 10.25 CRP IL1A IL1B IL6 MMP2 MMP9
6 integument MP:0010771 10.07 CTSC GUSB IL1A IL1B IL6 MMP9
7 mortality/aging MP:0010768 10.07 ELANE GUSB IL17A IL1B IL6 MMP2
8 craniofacial MP:0005382 10.04 GUSB IL17A IL1B MMP2 TNF TNFRSF11B
9 neoplasm MP:0002006 9.97 ELANE IL1A IL1B IL6 MMP1 MMP2
10 limbs/digits/tail MP:0005371 9.87 GUSB MMP9 TIMP1 TLR4 TNF TNFRSF11B
11 respiratory system MP:0005388 9.61 IL17A IL6 MMP2 MMP9 TIMP1 TLR2
12 skeleton MP:0005390 9.4 GUSB IL17A IL1B IL6 MMP2 MMP9

Drugs & Therapeutics for Periodontal Disease

Drugs for Periodontal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 484)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 443-48-1 4173
2
Levonorgestrel Approved, Investigational Phase 4 17489-40-6, 797-63-7 13109
3
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 564-25-0 54671203
4
Risedronate Approved, Investigational Phase 4 105462-24-6 5245
5
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 2713 9552079
6
Coal tar Approved Phase 4,Phase 3,Not Applicable 8007-45-2
7 sodium fluoride Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 7681-49-4
8
Ethanol Approved Phase 4,Phase 3,Phase 2,Not Applicable 64-17-5 702
9
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 9004-61-9 53477741
10
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 26787-78-0 33613
11
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-43-4 5816
12
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 329-65-7 838
13
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
14
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
15
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
16
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
17
Polyestradiol phosphate Approved Phase 4 28014-46-2
18
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 22916-47-8 4189
19
Hexetidine Approved, Investigational Phase 4 141-94-6
20
Triclosan Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 3380-34-5 5564
21
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 10118-90-8 5281021
22
Methyl salicylate Approved, Vet_approved Phase 4,Not Applicable 119-36-8 4133
23
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
24
Thymol Approved Phase 4,Not Applicable 89-83-8 6989
25
Azithromycin Approved Phase 4,Phase 2,Not Applicable 83905-01-5 55185 447043
26
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
27
Ciprofloxacin Approved, Investigational Phase 4,Phase 1,Not Applicable 85721-33-1 2764
28
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
29
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-78-2 2244
30
Polymyxin B Approved, Vet_approved Phase 4,Not Applicable 1404-26-8
31
Bacitracin Approved, Vet_approved Phase 4,Not Applicable 1405-87-4 439542 10909430
32
Neomycin Approved, Vet_approved Phase 4,Not Applicable 1404-04-2 8378
33
Prilocaine Approved Phase 4 721-50-6 4906
34
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 137-58-6 3676
35 Lycopene Approved, Investigational Phase 4,Phase 1,Phase 2 502-65-8 53477748
36
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
37
Turmeric Approved, Experimental, Investigational Phase 4,Not Applicable
38
Alendronate Approved Phase 4,Phase 2,Phase 3 66376-36-1, 121268-17-5 2088
39
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 32051
40
Pentetic acid Approved Phase 4,Not Applicable 67-43-6
41
Simvastatin Approved Phase 4,Phase 2,Phase 3 79902-63-9 54454
42
Edetic Acid Approved, Vet_approved Phase 4,Not Applicable 62-33-9, 60-00-4 6049
43
Clarithromycin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 81103-11-9 84029
44
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
45
Montelukast Approved Phase 4 158966-92-8 5281040
46
Silicon Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 7440-21-3 4082203
47
Diclofenac Approved, Vet_approved Phase 4,Phase 1,Phase 2 15307-86-5 3033
48
Benzydamine Approved Phase 4 100-46-9, 642-72-8 7504
49
Peppermint Approved Phase 4,Phase 1,Phase 2,Not Applicable
50
Flurbiprofen Approved, Investigational Phase 4,Phase 2 5104-49-4 3394

Interventional clinical trials:

(show top 50) (show all 1415)
# Name Status NCT ID Phase Drugs
1 The Treatment of Periodontal Diseases Unknown status NCT01318928 Phase 4 Metronidazol
2 Norplant and Irregular Bleeding/Spotting Unknown status NCT00064766 Phase 4 doxycycline
3 Effect of Actonel on Periodontal Health of Postmenopausal Women Unknown status NCT00594334 Phase 4 Risedronate
4 The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound Healing Unknown status NCT02826109 Phase 4
5 Role of Stress Reduction Protocol on Outcome of Periodontal Therapy Unknown status NCT02487862 Phase 4
6 Treatment of Periodontitis in Obese Individuals Unknown status NCT03103204 Phase 4
7 Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control Unknown status NCT03099551 Phase 4
8 Antiplaque Effect of Essential Oils With and Without Alcochol on an in Situ Model of Oral Biofilm Growth Unknown status NCT02946801 Phase 4 Essential oils;Essential oils without alcohol;Sterile water
9 Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets Unknown status NCT02391974 Phase 4
10 Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis Unknown status NCT02135952 Phase 4 MTZ+AMX
11 Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy Unknown status NCT01532674 Phase 4
12 Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care Unknown status NCT01195493 Phase 4
13 Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis Unknown status NCT00297531 Phase 4
14 SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis Unknown status NCT00296881 Phase 4
15 Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment Unknown status NCT02839421 Phase 4 Scaling and Root Planing combined with moxifloxacin
16 Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins Unknown status NCT02449707 Phase 4
17 Methodology Antiseptic Application, Influence on Oral Biofilm. Unknown status NCT02267239 Phase 4 essential oils, immersion;Chlorhexidine, immersion;essential oils, mouthwash;chlorhexidine, mouthwash
18 Effect of Probiotic Lozenges on Halitosis in Patients With Chronic Periodontitis Unknown status NCT02789436 Phase 4 L. reuteri Prodentis® lozenges
19 Pinhole Surgical Technique With And Without Use Of Buttons For Treatment Of Multiple Gingival Recessions: RCT Unknown status NCT02632968 Phase 4
20 Laser De-epithelialization for Epithelial Exclusion in Root Coverage Procedure: a Clinical Study Unknown status NCT02626117 Phase 4
21 Platelet Rich Fibrin in the Treatment of Palatal Wounds Unknown status NCT02438046 Phase 4
22 Efficacy of Different Chlorhexidine Concentrations Unknown status NCT02911766 Phase 4 Chlorhexidine 0.2% Mouthrinse;Chlorhexidine 0.12% mouthrinse;Chlorhexidine 0.06% mouthrinse
23 Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans Unknown status NCT01954485 Phase 4
24 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
25 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population Completed NCT01798225 Phase 4 Placebo;Doxycycline
26 Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers Completed NCT02670135 Phase 4 Triclosan Containing Toothpaste;Triclosan Free Toothpaste
27 Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. Completed NCT02102360 Phase 4
28 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. Completed NCT02487186 Phase 4 Doxicicline
29 EMD and/or Bone Substitute for the Treatment of Class II Furcations Completed NCT02474498 Phase 4 EMD
30 Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel Completed NCT01591616 Phase 4 lidocaine and prilocaine
31 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment Completed NCT02461030 Phase 4 In-office and at home Colgate sensitive pro-relief - CSPR;In-office Villevie® prophy paste + Colgate Toothpaste
32 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. Completed NCT03368430 Phase 4 Placebo
33 Study on Regenerative Treatment of Intra-bony Defects Completed NCT00757159 Phase 4
34 Long-term Safety of Minocycline in Patients With Gum Disease Completed NCT00668746 Phase 4 Minocycline HCl microspheres
35 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
36 A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease Completed NCT02065414 Phase 4
37 Photodynamic Therapy During Supportive Periodontal Therapy Completed NCT02666573 Phase 4
38 A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus Completed NCT02263352 Phase 4 Lycored soft gels Jagsonpal Pharma, Systemic 8mgms/day
39 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs Completed NCT02515929 Phase 4
40 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
41 Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects Completed NCT02886676 Phase 4 Spirulina capsules
42 Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing Completed NCT02197260 Phase 4 3/d 500 mg metronidazole plus 375 mg amoxicillin for 7 days
43 Evaluation of Photodynamic Treatment FOTOSAN® Efficacy in Periodontology Completed NCT02030470 Phase 4
44 Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin Completed NCT02641210 Phase 4 Albendazole
45 Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis. Completed NCT01211223 Phase 4 Administration of Metronidazole plus Amoxicillin
46 Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients Completed NCT02442453 Phase 4 Topical application of curenext gel;Placebo
47 Sodium Alendronate in Non Surgical Periodontal Therapy Completed NCT02470611 Phase 4 Sodium alendronate
48 Mechanical-chemical Gingival Therapy in Diabetics and/or Obese Completed NCT02123563 Phase 4
49 DFDBA and Xenograft (Cerabone)TM With Decortication in Intrabony Defects Completed NCT02949557 Phase 4
50 Treatment of Periodontitis by Conventional 4 Weekly Sections or Within 24 Hours Completed NCT02215460 Phase 4 FMS chlorhexidine rinse;FMS placebo rinse;FMS azithromycin tablets;FMS placebo tablets;QS azithromycin tablets;QS placebo tablets;QS chlorhexidine rinse;QS placebo rinse

Search NIH Clinical Center for Periodontal Disease

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: periodontal diseases

Genetic Tests for Periodontal Disease

Anatomical Context for Periodontal Disease

MalaCards organs/tissues related to Periodontal Disease:

42
Bone, Testes, Heart, Kidney, Neutrophil, Breast, T Cells

Publications for Periodontal Disease

Articles related to Periodontal Disease:

(show top 50) (show all 4079)
# Title Authors Year
1
Are There Any Common Genetic Risk Markers for Rheumatoid Arthritis and Periodontal Diseases? A Case-Control Study. ( 30890897 )
2019
2
Is there an association between asthma and periodontal disease among adults? Systematic review and meta-analysis. ( 30849418 )
2019
3
Effects of tamoxifen on periodontal disease and Candida albicans of patients with breast cancer and other pathologies. ( 30672328 )
2019
4
Dental caries are positively associated with periodontal disease severity. ( 30693397 )
2019
5
Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Ameliorates the Inflammatory Response in Periodontal Disease. ( 30793225 )
2019
6
Genetic and environmental contributions to the association between mood disorder and periodontal disease: A cross-sectional study among female twins in the UK. ( 30537144 )
2019
7
Exploring changes in oral hygiene behaviour in patients with diabetes and periodontal disease: A feasibility study. ( 30184336 )
2019
8
Periodontal disease and incident venous thromboembolism: The Atherosclerosis Risk in Communities study. ( 30362614 )
2019
9
Immune response mediated by Th1 / IL-17 / caspase-9 promotes evolution of periodontal disease. ( 30366216 )
2019
10
IL-1ß rs1143634 and rs16944 polymorphisms in patients with periodontal disease. ( 30445239 )
2019
11
Toll-like receptor 9 gene in Periodontal Disease - A promising biomarker. ( 30465884 )
2019
12
Polyphenols in the prevention and treatment of periodontal disease: A systematic review of in vivo, ex vivo and in vitro studies. ( 30496806 )
2019
13
Apolipoprotein E, periodontal disease and the risk for atherosclerosis: a review. ( 30503976 )
2019
14
Association of Periodontal Disease and Edentulism With Hypertension Risk in Postmenopausal Women. ( 30517596 )
2019
15
Updated Evidence of Association Between Periodontal Disease and Incident Erectile Dysfunction. ( 30621927 )
2019
16
Biologic modelling of periodontal disease progression. ( 30629741 )
2019
17
New insights in the link between malocclusion and periodontal disease. ( 30636328 )
2019
18
Association between periodontal disease and preterm prelabour rupture of membranes. ( 30638274 )
2019
19
Time to put periodontal disease on the list of chronic inflammatory diseases contributing to premature atherosclerosis. ( 30642827 )
2019
20
Immunohistochemical study of CD34 and podoplanin in periodontal disease. ( 30656679 )
2019
21
Relationship of periodontal disease and domains of Oral Health-related quality of life. ( 30657192 )
2019
22
Septic pulmonary embolism associated with periodontal disease: a case report and literature review. ( 30665352 )
2019
23
Azithromycin and Erythromycin susceptibility and macrolide resistance genes in Prevotella from patients with periodontal disease. ( 30667163 )
2019
24
Comparison of closed root planing with versus without concurrent doxycycline hyclate or clindamycin hydrochloride gel application for the treatment of periodontal disease in dogs. ( 30668243 )
2019
25
The role of autophagy in the pathogenesis of periodontal disease. ( 30674085 )
2019
26
The effect of diabetes on tooth loss due to periodontal disease: A nationwide population-based cohort study in South Korea. ( 30679838 )
2019
27
Periodontal disease may induce liver fibrosis in an experimental study on wistar rats. ( 30689209 )
2019
28
Antioxidant therapy (lycopene and green tea extract) in periodontal disease: A promising paradigm. ( 30692739 )
2019
29
Down-regulated Treg cells in exacerbated periodontal disease during pregnancy. ( 30753969 )
2019
30
Dysregulated Phosphate Metabolism, Periodontal Disease, and Cancer: Possible Global Health Implications. ( 30754693 )
2019
31
Effect of dental implant surface roughness in patients with a history of periodontal disease: a systematic review and meta-analysis. ( 30756245 )
2019
32
Dual micelles-loaded gelatin nanofibers and their application in lipopolysaccharide-induced periodontal disease. ( 30787610 )
2019
33
Periodontal Disease in Pregnancy: The Influence of General Factors and Inflammatory Mediators. ( 30793124 )
2019
34
Changes in alveolar process dimensions following extraction of molars with advanced periodontal disease: a clinical pilot study. ( 30803050 )
2019
35
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model. ( 30810635 )
2019
36
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1β, IL-10, RANK, OPG, MMP-2, TGF-β and TNF-α: follow-up over 5 years. ( 30810638 )
2019
37
Efficacy of β-caryophyllene for periodontal disease related factors. ( 30826504 )
2019
38
Association between Periodontal Disease and Subsequent Sjögren's Syndrome: A Nationwide Population-Based Cohort Study. ( 30832451 )
2019
39
Effect of Resveratrol on biofilm formation and virulence factor gene expression of Porphyromonas gingivalis in periodontal disease. ( 30861212 )
2019
40
Role of occlusion in periodontal disease. ( 30892765 )
2019
41
Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease. ( 30897827 )
2019
42
Erratum: Prevalence of periodontal disease in endemically flourosed areas of Davangere Taluk, India. ( 30900680 )
2019
43
Prevalence and analysis of equine periodontal disease, diastemata and peripheral caries in a first-opinion horse population in the UK. ( 30902197 )
2019
44
Evaluation of milk fat globule-epidermal growth factor-factor VIII and IL-1β levels in gingival crevicular fluid and saliva in periodontal disease and health. ( 30903320 )
2019
45
Complement-Dependent Mechanisms and Interventions in Periodontal Disease. ( 30915073 )
2019
46
The association between dyslipidemia, oral health behavior, and periodontal disease: The Korea National Health and Nutrition Examination Survey. ( 30915427 )
2019
47
Discovery of a Novel Periodontal Disease-Associated Bacterium. ( 29860637 )
2019
48
Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions: presentation of a patient with periodontitis localised to the molar teeth. ( 30734740 )
2019
49
Periodontal diagnosis in the context of the BSP implementation plan for the 2017 classification system of periodontal diseases and conditions: presentation of a patient with severe periodontitis following successful periodontal therapy and supportive periodontal treatment. ( 30903062 )
2019
50
Periodontal diagnosis in the context of the BSP implementation plan for the 2017 classification system of periodontal diseases and conditions: presentation of a pair of young siblings with periodontitis. ( 30631190 )
2019

Variations for Periodontal Disease

Expression for Periodontal Disease

Search GEO for disease gene expression data for Periodontal Disease.

Pathways for Periodontal Disease

Pathways related to Periodontal Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.77 CXCL8 IL17A IL1A IL1B IL6 TIMP1
2
Show member pathways
13.75 CRP CTSC CXCL8 DEFB1 ELANE GUSB
3
Show member pathways
13.53 CXCL8 IL17A IL1A IL1B IL6 TIMP1
4
Show member pathways
13.42 CXCL8 IL17A IL1A IL1B IL6 MMP1
5
Show member pathways
13.39 CXCL8 IL17A IL1A IL1B IL6 TIMP1
6
Show member pathways
13.26 CXCL8 IL1B IL6 TLR2 TLR4 TNF
7
Show member pathways
13.06 CXCL8 IL1B IL6 MMP9 TLR2 TLR4
8
Show member pathways
12.96 CXCL8 IL17A IL1A IL1B IL6 TNF
9 12.89 CXCL8 IL6 MMP1 MMP2 MMP9
10
Show member pathways
12.85 ELANE MMP1 MMP2 MMP8 MMP9 TIMP1
11
Show member pathways
12.85 IL1A IL1B IL6 TIMP1 TLR2 TLR4
12
Show member pathways