MCID: PRD007
MIFTS: 66

Periodontal Disease

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Periodontal Disease

MalaCards integrated aliases for Periodontal Disease:

Name: Periodontal Disease 12 77 15
Periodontal Diseases 56 45 74
Disease of Supporting Structures of Teeth 12
Periodontium Disorder 12
Gingival Diseases 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3388
MeSH 45 D010510
NCIt 51 C63743
SNOMED-CT 69 13877006 2556008
ICD10 34 K05.6 K08 K08.8

Summaries for Periodontal Disease

MalaCards based summary : Periodontal Disease, also known as periodontal diseases, is related to periodontosis and gingivitis, and has symptoms including snoring, halitosis and oral manifestations. An important gene associated with Periodontal Disease is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are PEDF Induced Signaling and Innate Immune System. The drugs Metronidazole and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include bone, heart and testes, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 77 Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the... more...

Related Diseases for Periodontal Disease

Diseases related to Periodontal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 525)
# Related Disease Score Top Affiliating Genes
1 periodontosis 32.5 CXCL8 ELANE MMP9 TLR4 TNF TNFSF11
2 gingivitis 31.8 CXCL8 ELANE GUSB IL1A IL1B IL6
3 aggressive periodontitis 31.7 CTSC CXCL8 IL1A IL1B IL6 MMP1
4 bone resorption disease 31.2 IL6 TNFRSF11B TNFSF11
5 heart disease 31.1 CRP CXCL8 IL1B IL6 TNF
6 periodontitis, chronic 30.9 IL1B IL6 MMP1 MMP8 TLR2 TNFRSF11B
7 atherosclerosis susceptibility 30.7 CRP IL6 TLR4 TNF
8 osteoporosis 30.7 IL1A IL1B IL6 TNF TNFRSF11B TNFSF11
9 arteries, anomalies of 30.7 CRP IL1B IL6 MMP9 TNF
10 arthritis 30.5 CXCL8 IL17A IL1A IL1B IL6 MMP1
11 familial mediterranean fever 30.5 CRP IL1B TNF
12 apnea, obstructive sleep 30.5 CRP IL6 TNF
13 end stage renal failure 30.5 CRP IL6 TNF
14 sleep apnea 30.3 CRP CXCL8 IL1B IL6 TNF
15 acquired immunodeficiency syndrome 30.3 IL1B IL6 TNF
16 root resorption 30.3 IL1A IL1B TNFRSF11B TNFSF11
17 ischemic heart disease 30.3 CRP IL6 TNF
18 endocarditis 30.2 CRP CXCL8 IL6 TLR2 TNF
19 periodontitis 30.2 CRP CTSC CXCL8 IL17A IL1A IL1B
20 osteoporotic fracture 30.2 IL6 TNFRSF11B
21 crohn's colitis 30.2 CXCL8 IL1B TNF
22 duodenal ulcer 30.2 CXCL8 IL1B TNF
23 placenta disease 30.2 CXCL8 IL1B IL6
24 pyoderma 30.1 CXCL8 MMP9 TNF
25 bacterial vaginosis 30.1 CXCL8 IL1A IL1B IL6 TLR2 TLR4
26 myocardial infarction 30.1 CRP IL1B IL6 MMP2 MMP9 TIMP1
27 cerebral palsy 30.1 IL1B IL6 MMP8 TNF
28 prostatitis 30.0 CXCL8 IL1B IL6 TNF
29 aphthous stomatitis 30.0 IL1B IL6 TLR2 TNF
30 autoimmune disease 30.0 IL17A IL1B IL6 TNF
31 infective endocarditis 29.9 CRP IL6 TLR2 TNF
32 vascular disease 29.9 CRP ELANE IL6 MMP9 TNF TNFRSF11B
33 bacterial pneumonia 29.9 CRP CXCL8 ELANE IL17A IL6 TLR4
34 juvenile rheumatoid arthritis 29.9 CRP IL1B IL6 TNF
35 cytomegalovirus infection 29.9 CXCL8 IL1B IL6 TNF
36 spondylitis 29.9 CRP IL17A IL6 TNF
37 periapical periodontitis 29.9 IL1B IL6 MMP8 TLR2 TNF TNFRSF11B
38 inflammatory bowel disease 29.8 CRP CXCL8 IL17A IL1B IL6 TLR2
39 cerebrovascular disease 29.8 CRP IL6 MMP9 TLR4 TNF
40 colitis 29.7 CXCL8 IL17A IL1B IL6 TLR4 TNF
41 spondyloarthropathy 1 29.7 CRP IL17A TLR4 TNF TNFRSF11B
42 pneumonia 29.7 CRP CXCL8 ELANE IL1B IL6 TLR2
43 systemic lupus erythematosus 29.7 CRP ELANE IL17A IL1B IL6 TLR2
44 gingival overgrowth 29.6 IL1A IL6 MMP1 MMP2 TIMP1
45 pulmonary emphysema 29.6 ELANE MMP1 MMP8 MMP9 TIMP1
46 ulcerative colitis 29.6 CRP CXCL8 IL17A IL1B IL6 TLR4
47 pulmonary disease, chronic obstructive 29.5 CRP CXCL8 ELANE IL17A IL6 MMP1
48 rheumatoid arthritis 29.5 CRP CXCL8 IL17A IL1A IL1B IL6
49 chlamydia 29.4 CRP CXCL8 IL1A IL1B IL6 TLR2
50 asthma 29.3 CXCL8 ELANE IL17A IL1A IL1B IL6

Graphical network of the top 20 diseases related to Periodontal Disease:



Diseases related to Periodontal Disease

Symptoms & Phenotypes for Periodontal Disease

UMLS symptoms related to Periodontal Disease:


snoring, halitosis, oral manifestations, tenderness of gums

MGI Mouse Phenotypes related to Periodontal Disease:

47 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.36 CRP CTSC ELANE GUSB IL17A IL1A
2 hematopoietic system MP:0005397 10.33 CTSC ELANE GUSB IL17A IL1A IL1B
3 immune system MP:0005387 10.33 CRP CTSC ELANE IL17A IL1A IL1B
4 growth/size/body region MP:0005378 10.29 CTSC GUSB IL17A IL1B IL6 MMP2
5 cardiovascular system MP:0005385 10.25 CRP IL1A IL1B IL6 MMP2 MMP9
6 integument MP:0010771 10.07 CTSC GUSB IL1A IL1B IL6 MMP9
7 mortality/aging MP:0010768 10.07 ELANE GUSB IL17A IL1B IL6 MMP2
8 craniofacial MP:0005382 10.04 GUSB IL17A IL1B MMP2 TNF TNFRSF11B
9 neoplasm MP:0002006 9.97 ELANE IL1A IL1B IL6 MMP1 MMP2
10 limbs/digits/tail MP:0005371 9.87 GUSB MMP9 TIMP1 TLR4 TNF TNFRSF11B
11 respiratory system MP:0005388 9.61 IL17A IL6 MMP2 MMP9 TIMP1 TLR2
12 skeleton MP:0005390 9.4 GUSB IL17A IL1B IL6 MMP2 MMP9

Drugs & Therapeutics for Periodontal Disease

Drugs for Periodontal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 491)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 443-48-1 4173
2
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 564-25-0 54671203
3
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
4
Risedronate Approved, Investigational Phase 4 105462-24-6 5245
5
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 55-56-1 2713 9552079
6
Coal tar Approved Phase 4,Phase 3,Not Applicable 8007-45-2
7
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 26787-78-0 33613
8 sodium fluoride Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 7681-49-4
9
Ethanol Approved Phase 4,Phase 3,Phase 2,Not Applicable 64-17-5 702
10
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 9004-61-9 53477741
11
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-43-4 5816
12
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 329-65-7 838
13
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
14
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
15
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
16
Polyestradiol phosphate Approved Phase 4 28014-46-2
17
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
18
Hexetidine Approved, Investigational Phase 4 141-94-6
19
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 22916-47-8 4189
20
Triclosan Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 3380-34-5 5564
21
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 10118-90-8 5281021
22
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
23
Thymol Approved Phase 4,Not Applicable 89-83-8 6989
24
Methyl salicylate Approved, Vet_approved Phase 4,Not Applicable 119-36-8 4133
25
Azithromycin Approved Phase 4,Phase 2,Not Applicable 83905-01-5 447043 55185
26
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
27
Ciprofloxacin Approved, Investigational Phase 4,Phase 1,Not Applicable 85721-33-1 2764
28
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
29
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-78-2 2244
30
Bacitracin Approved, Vet_approved Phase 4,Not Applicable 1405-87-4 10909430 439542
31
Neomycin Approved, Vet_approved Phase 4,Not Applicable 1404-04-2 8378
32
Polymyxin B Approved, Vet_approved Phase 4,Not Applicable 1404-26-8
33
Prilocaine Approved Phase 4 721-50-6 4906
34
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 137-58-6 3676
35 Lycopene Approved, Investigational Phase 4,Phase 1,Phase 2 502-65-8 53477748
36
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
37
Turmeric Approved, Experimental, Investigational Phase 4,Not Applicable
38
Alendronate Approved Phase 4,Phase 2,Phase 3 66376-36-1, 121268-17-5 2088
39
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 32051
40
Simvastatin Approved Phase 4,Phase 2,Phase 3 79902-63-9 54454
41
Pentetic acid Approved Phase 4,Not Applicable 67-43-6
42
Edetic Acid Approved, Vet_approved Phase 4,Not Applicable 60-00-4, 62-33-9 6049
43
Clarithromycin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 81103-11-9 84029
44
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
45
Montelukast Approved Phase 4 158966-92-8 5281040
46
Silicon Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 7440-21-3 4082203
47
Peppermint Approved Phase 4,Phase 1,Phase 2,Not Applicable
48
Flurbiprofen Approved, Investigational Phase 4,Phase 2 5104-49-4 3394
49
Diclofenac Approved, Vet_approved Phase 4,Phase 1,Phase 2 15307-86-5 3033
50
Benzydamine Approved Phase 4 642-72-8, 100-46-9 7504

Interventional clinical trials:

(show top 50) (show all 1450)
# Name Status NCT ID Phase Drugs
1 The Treatment of Periodontal Diseases Unknown status NCT01318928 Phase 4 Metronidazol
2 Norplant and Irregular Bleeding/Spotting Unknown status NCT00064766 Phase 4 doxycycline
3 Effect of Actonel on Periodontal Health of Postmenopausal Women Unknown status NCT00594334 Phase 4 Risedronate
4 The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound Healing Unknown status NCT02826109 Phase 4
5 Role of Stress Reduction Protocol on Outcome of Periodontal Therapy Unknown status NCT02487862 Phase 4
6 Treatment of Periodontitis in Obese Individuals Unknown status NCT03103204 Phase 4
7 Dose and Duration of Metronidazole and Amoxicillin for Treatment of Chronic Periodontitis Unknown status NCT02735395 Phase 4 Metronidazole 250 (7 days);Metronidazole 400 (7 days);Metronidazole 250 (14 days);Metronidazole 400 (14 days);Amoxicillin
8 Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control Unknown status NCT03099551 Phase 4
9 Antiplaque Effect of Essential Oils With and Without Alcochol on an in Situ Model of Oral Biofilm Growth Unknown status NCT02946801 Phase 4 Essential oils;Essential oils without alcohol;Sterile water
10 Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets Unknown status NCT02391974 Phase 4
11 Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis Unknown status NCT02135952 Phase 4 MTZ+AMX
12 Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy Unknown status NCT01532674 Phase 4
13 Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care Unknown status NCT01195493 Phase 4
14 Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis Unknown status NCT00297531 Phase 4
15 SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis Unknown status NCT00296881 Phase 4
16 Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment Unknown status NCT02839421 Phase 4 Scaling and Root Planing combined with moxifloxacin
17 Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins Unknown status NCT02449707 Phase 4
18 Methodology Antiseptic Application, Influence on Oral Biofilm. Unknown status NCT02267239 Phase 4 essential oils, immersion;Chlorhexidine, immersion;essential oils, mouthwash;chlorhexidine, mouthwash
19 Essential Oils With and Without Alcohol: Substantivity and Antiplaque Effect Unknown status NCT03146390 Phase 4 Essential oils;Alcohol free essential oils
20 Effect of Probiotic Lozenges on Halitosis in Patients With Chronic Periodontitis Unknown status NCT02789436 Phase 4 L. reuteri Prodentis® lozenges
21 Pinhole Surgical Technique With And Without Use Of Buttons For Treatment Of Multiple Gingival Recessions: RCT Unknown status NCT02632968 Phase 4
22 Laser De-epithelialization for Epithelial Exclusion in Root Coverage Procedure: a Clinical Study Unknown status NCT02626117 Phase 4
23 Platelet Rich Fibrin in the Treatment of Palatal Wounds Unknown status NCT02438046 Phase 4
24 Efficacy of Different Chlorhexidine Concentrations Unknown status NCT02911766 Phase 4 Chlorhexidine 0.2% Mouthrinse;Chlorhexidine 0.12% mouthrinse;Chlorhexidine 0.06% mouthrinse
25 Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans Unknown status NCT01954485 Phase 4
26 Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis Unknown status NCT03047291 Phase 4 Probiotic
27 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
28 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population Completed NCT01798225 Phase 4 Placebo;Doxycycline
29 Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers Completed NCT02670135 Phase 4 Triclosan Containing Toothpaste;Triclosan Free Toothpaste
30 Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. Completed NCT02102360 Phase 4
31 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. Completed NCT02487186 Phase 4 Doxicicline
32 EMD and/or Bone Substitute for the Treatment of Class II Furcations Completed NCT02474498 Phase 4 EMD
33 Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel Completed NCT01591616 Phase 4 lidocaine and prilocaine
34 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment Completed NCT02461030 Phase 4 In-office and at home Colgate sensitive pro-relief - CSPR;In-office Villevie® prophy paste + Colgate Toothpaste
35 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. Completed NCT03368430 Phase 4 Placebo
36 Study on Regenerative Treatment of Intra-bony Defects Completed NCT00757159 Phase 4
37 Long-term Safety of Minocycline in Patients With Gum Disease Completed NCT00668746 Phase 4 Minocycline HCl microspheres
38 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
39 A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease Completed NCT02065414 Phase 4
40 Photodynamic Therapy During Supportive Periodontal Therapy Completed NCT02666573 Phase 4
41 A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus Completed NCT02263352 Phase 4 Lycored soft gels Jagsonpal Pharma, Systemic 8mgms/day
42 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs Completed NCT02515929 Phase 4
43 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
44 Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects Completed NCT02886676 Phase 4 Spirulina capsules
45 Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing Completed NCT02197260 Phase 4 3/d 500 mg metronidazole plus 375 mg amoxicillin for 7 days
46 Evaluation of Photodynamic Treatment FOTOSAN® Efficacy in Periodontology Completed NCT02030470 Phase 4
47 Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin Completed NCT02641210 Phase 4 Albendazole
48 Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis. Completed NCT01211223 Phase 4 Administration of Metronidazole plus Amoxicillin
49 Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients Completed NCT02442453 Phase 4 Topical application of curenext gel;Placebo
50 Sodium Alendronate in Non Surgical Periodontal Therapy Completed NCT02470611 Phase 4 Sodium alendronate

Search NIH Clinical Center for Periodontal Disease

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: periodontal diseases

Genetic Tests for Periodontal Disease

Anatomical Context for Periodontal Disease

MalaCards organs/tissues related to Periodontal Disease:

42
Bone, Heart, Testes, Kidney, Neutrophil, T Cells, Ovary

Publications for Periodontal Disease

Articles related to Periodontal Disease:

(show top 50) (show all 4118)
# Title Authors Year
1
Optical coherence tomography follow-up of patients treated from periodontal disease. ( 30260081 )
2019
2
Exploring changes in oral hygiene behaviour in patients with diabetes and periodontal disease: A feasibility study. ( 30184336 )
2019
3
Psychometric approach of the revised illness perception questionnaire for oral health (IPQ-R-OH) in patients with periodontal disease. ( 30176171 )
2019
4
A New Target to Ameliorate the Damage of Periodontal Disease: The Role of Transient Receptor Potential Vanilloid Type-1 in Contrast to That of Specific Cannabinoid Receptors in Rats. ( 31077362 )
2019
5
Effects of tamoxifen on periodontal disease and Candida albicans of patients with breast cancer and other pathologies. ( 30672328 )
2019
6
The salivary microbiome of diabetic and non-diabetic adults with periodontal disease. ( 29999529 )
2019
7
From manual periodontal probing to digital 3-D imaging to endoscopic capillaroscopy: Recent advances in periodontal disease diagnosis. ( 29974960 )
2019
8
Contribution of Diabetes to the Incidence and Prevalence of Comorbid Conditions (Cancer, Periodontal Disease, Fracture, Impaired Cognitive Function, and Depression): A Systematic Review of Epidemiological Studies in Japanese Populations. ( 29937469 )
2019
9
Discovery of a Novel Periodontal Disease-Associated Bacterium. ( 29860637 )
2019
10
Periodontal Disease Is Associated With Increased Risk of Hypertension: A Cross-Sectional Study. ( 31105578 )
2019
11
The effect of vanillic acid on ligature-induced periodontal disease in Wistar rats. ( 31103800 )
2019
12
The role of serum lipoxin A4 levels in the association between periodontal disease and metabolic syndrome. ( 31098331 )
2019
13
Long-term assessment of periodontal disease progression after surgical or non-surgical treatment: a systematic review. ( 31098328 )
2019
14
Salivary free hemoglobin and lactate dehydrogenase as biomarkers for periodontal disease in smokers. ( 31086854 )
2019
15
There is probably a higher prevalence of periodontal disease in cannabis users than in nonusers. ( 31076077 )
2019
16
Dairy Food Consumption is Inversely Associated with the Prevalence of Periodontal Disease in Korean Adults. ( 31075833 )
2019
17
Comparison of two measures to determine the oral health-related quality of life in elders with periodontal disease. ( 31070876 )
2019
18
Effect of Weight Reduction on the Serum Adiponectin and Tumor Necrosis Factor-α Levels and the Clinical Parameters of Obese Patients with and without Periodontal Disease. ( 31058067 )
2019
19
Can Resveratrol Treatment Control the Progression of Induced Periodontal Disease? A Systematic Review and Meta-Analysis of Preclinical Studies. ( 31035477 )
2019
20
Array analysis for T-cell associated cytokines in gingival crevicular fluid; identifying altered profiles associated with periodontal disease status. ( 31028890 )
2019
21
Re: Updated Evidence of Association between Periodontal Disease and Incident Erectile Dysfunction. ( 31009980 )
2019
22
Dietary intake in patients with peripheral arterial disease and concomitant periodontal disease. ( 31006393 )
2019
23
In- vitro-activity of additive application of hydrogen peroxide in antimicrobial photodynamic therapy using LED in the blue spectrum against bacteria and biofilm being associated with periodontal disease. ( 31002887 )
2019
24
Dental treatment procedures for periodontal disease and the subsequent risk of ischaemic stroke: A retrospective population-based cohort study. ( 30989681 )
2019
25
Analysis of association between periodontal disease and thickness of maxillary sinus mucosa using cone beam computed tomography - A retrospective study. ( 30983833 )
2019
26
Do genetic polymorphisms affect susceptibility to periodontal disease? A literature review. ( 30975946 )
2019
27
Periodontal Disease May be Associated With the Occurrence of Diabetic Retinopathy: A Subgroup Analysis of The Survey of the Diabetes Coordination Notebook in Gifu. ( 30974473 )
2019
28
Autophagy in periodontal disease: Evidence from a literature review. ( 30974378 )
2019
29
Role of Dental Implant Superstructure in Patients with Severe Periodontal Disease. ( 30971678 )
2019
30
Association between Regular Electronic Nicotine Product Use and Self-reported Periodontal Disease Status: Population Assessment of Tobacco and Health Survey. ( 30970567 )
2019
31
Physical Activity Reduces the Prevalence of Periodontal Disease: Systematic Review and Meta-Analysis. ( 30949062 )
2019
32
Is there socioeconomic inequality in periodontal disease among adults with optimal behaviours. ( 30919709 )
2019
33
The association between dyslipidemia, oral health behavior, and periodontal disease: The Korea National Health and Nutrition Examination Survey. ( 30915427 )
2019
34
Complement-Dependent Mechanisms and Interventions in Periodontal Disease. ( 30915073 )
2019
35
Evaluation of milk fat globule-epidermal growth factor-factor VIII and IL-1β levels in gingival crevicular fluid and saliva in periodontal disease and health. ( 30903320 )
2019
36
Prevalence and analysis of equine periodontal disease, diastemata and peripheral caries in a first-opinion horse population in the UK. ( 30902197 )
2019
37
Erratum: Prevalence of periodontal disease in endemically flourosed areas of Davangere Taluk, India. ( 30900680 )
2019
38
Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease. ( 30897827 )
2019
39
Role of occlusion in periodontal disease. ( 30892765 )
2019
40
Effect of Resveratrol on biofilm formation and virulence factor gene expression of Porphyromonas gingivalis in periodontal disease. ( 30861212 )
2019
41
Association between Periodontal Disease and Subsequent Sjögren's Syndrome: A Nationwide Population-Based Cohort Study. ( 30832451 )
2019
42
Efficacy of β-caryophyllene for periodontal disease related factors. ( 30826504 )
2019
43
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1β, IL-10, RANK, OPG, MMP-2, TGF-β and TNF-α: follow-up over 5 years. ( 30810638 )
2019
44
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model. ( 30810635 )
2019
45
Changes in alveolar process dimensions following extraction of molars with advanced periodontal disease: a clinical pilot study. ( 30803050 )
2019
46
Periodontal Disease in Pregnancy: The Influence of General Factors and Inflammatory Mediators. ( 30793124 )
2019
47
Dual micelles-loaded gelatin nanofibers and their application in lipopolysaccharide-induced periodontal disease. ( 30787610 )
2019
48
Effect of dental implant surface roughness in patients with a history of periodontal disease: a systematic review and meta-analysis. ( 30756245 )
2019
49
Dysregulated Phosphate Metabolism, Periodontal Disease, and Cancer: Possible Global Health Implications. ( 30754693 )
2019
50
Down-regulated Treg cells in exacerbated periodontal disease during pregnancy. ( 30753969 )
2019

Variations for Periodontal Disease

Expression for Periodontal Disease

Search GEO for disease gene expression data for Periodontal Disease.

Pathways for Periodontal Disease

Pathways related to Periodontal Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.77 CXCL8 IL17A IL1A IL1B IL6 TIMP1
2
Show member pathways
13.75 CRP CTSC CXCL8 DEFB1 ELANE GUSB
3
Show member pathways
13.53 CXCL8 IL17A IL1A IL1B IL6 TIMP1
4
Show member pathways
13.42 CXCL8 IL17A IL1A IL1B IL6 MMP1
5
Show member pathways
13.39 CXCL8 IL17A IL1A IL1B IL6 TIMP1
6
Show member pathways
13.17 CXCL8 IL1B IL6 TLR2 TLR4 TNF
7
Show member pathways
13.06 CXCL8 IL1B IL6 MMP9 TLR2 TLR4
8
Show member pathways
12.96 CXCL8 IL17A IL1A IL1B IL6 TNF
9 12.89 CXCL8 IL6 MMP1 MMP2 MMP9
10
Show member pathways
12.85 ELANE MMP1 MMP2 MMP8 MMP9 TIMP1
11
Show member pathways
12.85 IL1A IL1B IL6 TIMP1 TLR2 TLR4
12
Show member pathways