MCID: PRS016
MIFTS: 24

Periosteal Chondrosarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Periosteal Chondrosarcoma

MalaCards integrated aliases for Periosteal Chondrosarcoma:

Name: Periosteal Chondrosarcoma 12 15
Juxtacortical Chondrosarcoma 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5859
UMLS 70 C0334549

Summaries for Periosteal Chondrosarcoma

MalaCards based summary : Periosteal Chondrosarcoma, also known as juxtacortical chondrosarcoma, is related to chondrosarcoma and juxtacortical chondroma, and has symptoms including pain An important gene associated with Periosteal Chondrosarcoma is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1), and among its related pathways/superpathways are Chromatin Regulation / Acetylation and Central carbon metabolism in cancer. Affiliated tissues include bone and lymph node.

Related Diseases for Periosteal Chondrosarcoma

Diseases related to Periosteal Chondrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 chondrosarcoma 30.3 NCOA2 IDH2 IDH1 EXT1
2 juxtacortical chondroma 30.3 IDH2 IDH1 EXT1
3 chondroblastic osteosarcoma 30.2 IDH2 IDH1
4 osteochondroma 29.6 NCOA2 EXT1
5 enchondroma 10.2 IDH2 IDH1
6 adult brain stem glioma 10.2 IDH2 IDH1
7 brain stem glioma 10.2 IDH2 IDH1
8 cytogenetically normal acute myeloid leukemia 10.2 IDH2 IDH1
9 intracranial chondrosarcoma 10.2 IDH2 IDH1
10 adult oligodendroglioma 10.2 IDH2 IDH1
11 childhood oligodendroglioma 10.2 IDH2 IDH1
12 chondroma 10.2
13 gemistocytic astrocytoma 10.2 IDH2 IDH1
14 adult astrocytic tumour 10.2 IDH2 IDH1
15 mixed oligodendroglioma-astrocytoma 10.2 IDH2 IDH1
16 mixed glioma 10.2 IDH2 IDH1
17 low grade glioma 10.2 IDH2 IDH1
18 spindle cell hemangioma 10.1 IDH2 IDH1
19 d-2-hydroxyglutaric aciduria 1 10.1 IDH2 IDH1
20 osteogenic sarcoma 10.1
21 malignant fibrous histiocytoma 10.1
22 fibrous histiocytoma 10.1
23 periosteal osteogenic sarcoma 10.1
24 2-hydroxyglutaric aciduria 10.1 IDH2 IDH1
25 l-2-hydroxyglutaric aciduria 10.1 IDH2 IDH1
26 diffuse astrocytoma 10.0 IDH2 IDH1
27 multiple enchondromatosis, maffucci type 10.0 IDH2 IDH1 EXT1
28 bone sarcoma 10.0 IDH2 IDH1 EXT1
29 miyoshi muscular dystrophy 3 10.0 METTL3 METTL14
30 exostoses, multiple, type i 10.0
31 childhood acute myeloid leukemia 9.9 IDH2 IDH1
32 enchondromatosis, multiple, ollier type 9.7 YEATS2 IDH2 IDH1 EXT1
33 wilms tumor 1 9.6 YTHDC1 METTL3 METTL14 ALKBH5
34 leukemia, acute myeloid 9.2 NCOA2 METTL3 IDH2 IDH1

Graphical network of the top 20 diseases related to Periosteal Chondrosarcoma:



Diseases related to Periosteal Chondrosarcoma

Symptoms & Phenotypes for Periosteal Chondrosarcoma

UMLS symptoms related to Periosteal Chondrosarcoma:


pain

Drugs & Therapeutics for Periosteal Chondrosarcoma

Search Clinical Trials , NIH Clinical Center for Periosteal Chondrosarcoma

Genetic Tests for Periosteal Chondrosarcoma

Anatomical Context for Periosteal Chondrosarcoma

MalaCards organs/tissues related to Periosteal Chondrosarcoma:

40
Bone, Lymph Node

Publications for Periosteal Chondrosarcoma

Articles related to Periosteal Chondrosarcoma:

(show top 50) (show all 54)
# Title Authors PMID Year
1
A review of imaging of surface sarcomas of bone. 61
32681279 2021
2
Traumatic Glenosphere Dissociation Following Reverse Total Shoulder Endoprosthetic Reconstruction for Proximal Humerus Periosteal Chondrosarcoma: A Case Report. 61
33708714 2020
3
Quantitative bone SPECT/CT applications for cartilaginous bone neoplasms. 61
32716404 2020
4
Unusual Focal Muscle FDG Activity Related to Altered Biomechanics. 61
30516674 2019
5
[Costal periosteal chondrosarcoma: A rare entity]. 61
29459126 2018
6
Marginal resection in a case of juxtacortical chondrosarcoma of the mandible. 61
29937670 2018
7
Integrating Morphology and Genetics in the Diagnosis of Cartilage Tumors. 61
28797501 2017
8
Diagnosis and Outcome of Periosteal Chondrosarcoma in Two Cats. 61
27487347 2016
9
Recurrence of juxtacortical chondrosarcoma arising on the rib. 61
24902930 2016
10
Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype. 61
25648524 2015
11
Primary juxtacortical chondrosarcoma of mandibular symphysis: Unique and rare case report. 61
26881593 2015
12
Bony metastases following complete resection of periosteal chondrosarcoma. 61
25889026 2015
13
A case of benign periosteal chondroma seeding into humeral medullary bone via percutaneous needle biopsy tract. 61
30363208 2015
14
The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands. 61
24891585 2014
15
Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: A case report. 61
24932240 2014
16
Juxtacortical clavicular chondrosarcoma: diagnostic dilemmas: case report and review of literature. 61
23400393 2013
17
Periosteal chondrosarcoma of metacarpal bone: Report of a rare entity. 61
23289049 2012
18
Peripheral ossifying fibroma and juxtacortical chondrosarcoma in cynomolgus monkeys (Macaca fascicularis). 61
21333171 2011
19
Fine-needle aspiration biopsy diagnosis of costal juxtacortical chondrosarcoma presenting as an abdominal mass. 61
20187114 2010
20
Periosteal chondrosarcoma of the foot: a case report. 61
20576447 2010
21
Mandibular periosteal (juxtacortical) chondrosarcoma. 61
20126915 2009
22
Periosteal chondrosarcoma. 61
19098166 2009
23
Periosteal chondrosarcoma with microscopic cortical invasion. 61
18696199 2008
24
Soft tissue osteochondroma: case report and immunohistochemistry for parathyroid hormone-related protein. 61
16844564 2006
25
Survivorship analysis in patients with periosteal chondrosarcoma. 61
16826117 2006
26
Periosteal chondrosarcoma in a 9-year-old girl with osteochondromatosis. 61
15723209 2005
27
Juxtacortical chondrosarcoma of the mandible: report of a unique case and review of the literature. 61
15617976 2005
28
Histological findings in a human autogenous pasteurized bone graft. 61
15274371 2004
29
Periosteal chondrosarcoma. 61
12938935 2003
30
Periosteal chondrosarcoma. 61
12195911 2002
31
Radiological features of 24 periosteal chondrosarcomas. 61
11392294 2001
32
Giant juxtacortical chondrosarcoma of the humerus. 61
10825120 2000
33
Periosteal osteosarcoma of the jaws: report of 2 cases. 61
10711625 2000
34
DNA ploidy alterations detected during dedifferentiation of periosteal chondrosarcoma. 61
10472345 1999
35
Primary juxtacortical chondrosarcoma dedifferentiating after 20 years. 61
9840394 1998
36
Case 1: Juxtacortical chondrosarcoma. 61
9725340 1998
37
[Juxtacortical chondrosarcoma. A entity to be differentiated from periosteal osteosarcoma]. 61
9471159 1997
38
Periosteal chondrosarcoma invading the medullary cavity. 61
9229422 1997
39
Periosteal chondrosarcoma: a case report and review of the literature. 61
9111097 1997
40
Juxtacortical dedifferentiated chondrosarcoma from a primary periosteal chondrosarcoma. 61
8685228 1996
41
MR appearance of periosteal chondrosarcoma of the foot. 61
7822524 1995
42
Periosteal osteosarcoma and parosteal chondrosarcoma evaluated by double immunohistochemical staining. Report of 2 cases. 61
7518993 1994
43
Parosteal (juxtacortical) chondrosarcoma of the humerus associated with regional lymph node metastasis. A case report. 61
8472444 1993
44
Periosteal chondroma and periosteal chondrosarcoma. 61
4051099 1985
45
Periosteal osteosarcoma. 61
3965078 1985
46
Current trends in the diagnosis and treatment of malignant bone tumors. 61
6313271 1983
47
Periosteal chondroma. A clinicopathologic study of 23 cases. 61
7180962 1982
48
Periosteal chondrosarcoma and periosteal osteosarcoma. Two distinct entities. 61
7096408 1982
49
Juxtacortical chondrosarcoma. 61
270475 1977
50
Periosteal (juxtacortical) chondrosarcoma: report of a case occurring in the hand. 61
893986 1977

Variations for Periosteal Chondrosarcoma

Expression for Periosteal Chondrosarcoma

Search GEO for disease gene expression data for Periosteal Chondrosarcoma.

Pathways for Periosteal Chondrosarcoma

Pathways related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.54 YTHDC1 METTL3 METTL14
2 11 IDH2 IDH1
3
Show member pathways
9.74 IDH2 IDH1

GO Terms for Periosteal Chondrosarcoma

Cellular components related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA N6-methyladenosine methyltransferase complex GO:0036396 8.62 METTL3 METTL14

Biological processes related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 mRNA splicing, via spliceosome GO:0000398 9.7 YTHDC1 METTL3 METTL14
2 stem cell population maintenance GO:0019827 9.55 METTL3 METTL14
3 RNA metabolic process GO:0016070 9.54 METTL3 METTL14
4 tricarboxylic acid cycle GO:0006099 9.51 IDH2 IDH1
5 mRNA catabolic process GO:0006402 9.49 METTL3 METTL14
6 RNA methylation GO:0001510 9.48 METTL3 METTL14
7 mRNA destabilization GO:0061157 9.46 METTL3 METTL14
8 2-oxoglutarate metabolic process GO:0006103 9.43 IDH2 IDH1
9 mRNA methylation GO:0080009 9.4 METTL3 METTL14
10 dosage compensation by inactivation of X chromosome GO:0009048 9.37 YTHDC1 METTL3
11 NADP metabolic process GO:0006739 9.32 IDH2 IDH1
12 gliogenesis GO:0042063 9.26 METTL3 METTL14
13 forebrain radial glial cell differentiation GO:0021861 9.16 METTL3 METTL14
14 isocitrate metabolic process GO:0006102 8.96 IDH2 IDH1
15 glyoxylate cycle GO:0006097 8.62 IDH2 IDH1

Molecular functions related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding GO:0003729 9.5 YTHDC1 METTL3 METTL14
2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.4 IDH2 IDH1
3 NAD binding GO:0051287 9.37 IDH2 IDH1
4 S-adenosyl-L-methionine binding GO:1904047 9.26 METTL3 METTL14
5 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity GO:0016422 9.16 METTL3 METTL14
6 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH2 IDH1
7 isocitrate dehydrogenase activity GO:0004448 8.62 IDH2 IDH1

Sources for Periosteal Chondrosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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