Aliases & Classifications for Periostitis

MalaCards integrated aliases for Periostitis:

Name: Periostitis 12 43 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9957
MeSH 43 D010522
SNOMED-CT 67 41910004
ICD10 32 M90.1
UMLS 71 C0031111

Summaries for Periostitis

Disease Ontology : 12 A connective tissue disease characterized by inflammation located in the periosteum of the bone.

MalaCards based summary : Periostitis is related to osteomyelitis and bone resorption disease. An important gene associated with Periostitis is IL1RN (Interleukin 1 Receptor Antagonist), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Parasympatholytics and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include periosteum of the bone, bone and lung, and related phenotype is immune system.

Wikipedia : 74 Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the... more...

Related Diseases for Periostitis

Diseases related to Periostitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 535)
# Related Disease Score Top Affiliating Genes
1 osteomyelitis 31.0 LPIN2 IL1RN IL1A
2 bone resorption disease 30.8 TNFRSF11B TNFRSF11A HECTD4 CRP
3 fasciitis 30.6 IL1RN HECTD4 CRP
4 paget disease of bone 5, juvenile-onset 30.3 TNFRSF11B TNFRSF11A
5 mammary paget's disease 30.2 TNFRSF11B TNFRSF11A SQSTM1
6 arthropathy 30.2 TNFRSF11B TNFRSF11A IL1RN CRP
7 paget disease of bone 2, early-onset 30.2 TNFRSF11A SQSTM1
8 enthesopathy 30.2 MRAP HECTD4 CRP
9 chondromalacia 30.1 MRAP IL1RN CRP
10 periodontitis 30.1 TNFRSF11B IL1RN IL1A CRP
11 plantar fasciitis 30.1 MRAP HECTD4
12 osteoarthritis 30.1 TNFRSF11B IL1RN IL1A CRP
13 otitis media 30.1 IL1RN IL1A CRP
14 neurogenic arthropathy 30.1 HECTD4 CRP
15 synovitis 30.0 TNFRSF11B IL1RN IL1A CRP
16 optic papillitis 30.0 MRAP CRP
17 familial expansile osteolysis 30.0 TNFRSF11B TNFRSF11A SQSTM1
18 paget's disease of bone 30.0 TNFRSF11B TNFRSF11A SQSTM1 ALPP
19 scleritis 29.9 MRAP IL1RN CRP
20 iritis 29.9 MRAP CRP
21 sapho syndrome 29.9 PSTPIP1 MRAP LPIN2 IL1RN
22 ankylosis 29.9 TNFRSF11B MRAP CRP
23 bone disease 29.9 TNFRSF11B TNFRSF11A IL1A IL11 ALPP
24 periapical periodontitis 29.7 TNFRSF11B IL1A
25 spondyloarthropathy 1 29.7 TNFRSF11B MRAP IL1RN CRP
26 gingival disease 29.6 TNFRSF11B IL1A CRP
27 tenosynovitis 29.6 MRAP IL1RN HECTD4 CRP
28 bone inflammation disease 29.6 TNFRSF11B MRAP IL1RN IL1A HECTD4 CRP
29 sarcoidosis 1 29.5 MRAP IL1RN IL1A CRP
30 bronchiolitis 29.5 IL1A IL11 CRP
31 arthritis 29.3 TNFRSF11A PSTPIP1 IL1RN IL1A CRP
32 pneumonia 29.3 IL1RN IL1A IL11 CRP
33 spondylolisthesis 29.2 HECTD4 CRP
34 connective tissue disease 29.2 TNFRSF11B MRAP IL1A CRP
35 vascular disease 29.2 TNFRSF11B TNFRSF11A IL1A CRP
36 rheumatoid arthritis 29.1 TNFRSF11B TNFRSF11A IL1RN IL1A IL11 CRP
37 osteoporosis 29.0 TNFRSF11B TNFRSF11A IL1RN IL1A IL11 CRP
38 psoriatic arthritis 28.9 TNFRSF11B IL36RN IL1RN IL1A CRP CARD14
39 chronic recurrent multifocal osteomyelitis 28.7 PSTPIP1 MRAP LPIN2 IL1RN HECTD4 CRP
40 pustulosis of palm and sole 27.9 PSTPIP1 MRAP LPIN2 IL36RN IL1RN IL1RL2
41 osteomyelitis, sterile multifocal, with periostitis and pustulosis 12.6
42 periosteal osteogenic sarcoma 12.5
43 alveolar periostitis 12.4
44 periosteal chondrosarcoma 12.4
45 orbital periostitis 12.4
46 tumoral calcinosis, hyperphosphatemic, familial, 1 11.6
47 juxtacortical chondroma 11.6
48 osteogenic sarcoma 11.6
49 melorheostosis 11.5
50 caffey disease 11.5

Graphical network of the top 20 diseases related to Periostitis:



Diseases related to Periostitis

Symptoms & Phenotypes for Periostitis

MGI Mouse Phenotypes related to Periostitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.4 CARD14 CRP IL1A IL1F10 IL1RL2 IL1RN

Drugs & Therapeutics for Periostitis

Drugs for Periostitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Parasympatholytics
2 Analgesics
3 Hypnotics and Sedatives

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Investigation of Therapeutic Effect and Molecular Mechanism After Intravascular Laser Irradiation of Blood Not yet recruiting NCT03724799
2 Effect of Shortwave Diathermy Versus Therapeutic Ultrasound on Medial Tibial Stress Syndrome Among Military Cadets Not yet recruiting NCT04292795

Search NIH Clinical Center for Periostitis

Cochrane evidence based reviews: periostitis

Genetic Tests for Periostitis

Anatomical Context for Periostitis

The Foundational Model of Anatomy Ontology organs/tissues related to Periostitis:

19
Periosteum Of The Bone

MalaCards organs/tissues related to Periostitis:

40
Bone, Lung, Liver, Bone Marrow, Eye, Thymus, Heart

Publications for Periostitis

Articles related to Periostitis:

(show top 50) (show all 888)
# Title Authors PMID Year
1
Correction to: Voriconazole-induced periostitis in stem cell transplant patient. 61
32562086 2020
2
Voriconazole-induced periostitis in stem cell transplant patient. 61
32430648 2020
3
Investigation of a bone lesion in a gorgonopsian (Synapsida) from the Permian of Zambia and periosteal reactions in fossil non-mammalian tetrapods. 61
31928188 2020
4
Downregulation of serum miR-194 predicts poor prognosis in osteosarcoma patients. 61
32172218 2020
5
Late onset hyperplastic callus formation in osteogenesis imperfecta type V simulating osteosarcoma-A case report. 61
32305663 2020
6
Periostitis ossificans in a 10-year-old child. 61
32174634 2020
7
Trends in Systemic Antibiotic Therapy of Endodontic Infections: a Survey among Dental Practitioners in Lithuania. 61
32377326 2020
8
Periapical and Endodontic Status Scale for Endodontically Treated Teeth and Their Association with Maxillary Sinus Abnormalities: A Cone-beam Computed Tomographic Study. 61
31630784 2019
9
Voriconazole-associated periostitis presenting as hypertrophic osteoarthropathy following lung transplantation report of two cases and review of the literature. 61
31103239 2019
10
Voriconazole-Induced Periostitis. 61
31597023 2019
11
Dental students' ability to detect maxillary sinus abnormalities: A comparison between panoramic radiography and cone-beam computed tomography. 61
31583201 2019
12
Voriconazole-Induced Periostitis: Radiological Clues for its Diagnosis. 61
29319553 2019
13
Correlation of 3-T MRI and CT findings with patient symptoms and treatment outcome in radiofrequency ablation of osteoid osteoma. 61
31104885 2019
14
Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents. 61
31093949 2019
15
Chronic osteomyelitis with proliferative periostitis of the mandibular body: report of a case and review of the literature. 61
30855166 2019
16
Syphilis with Charcot arthropathy: A case report. 61
30758895 2019
17
Animal model of arthritis and myositis induced by the Mayaro virus. 61
31050676 2019
18
Successful Treatment of ROS1-rearranged Lung Cancer Complicated by Hypertrophic Pulmonary Osteoarthropathy with Crizotinib Therapy. 61
30626830 2019
19
Florid Reactive Periostitis of the Proximal Phalanx-Case Report and Literature Review. 61
31363290 2019
20
[Voriconazole-induced periostitis]. 61
31036146 2019
21
Pathology in the appendicular bones of southern tamandua, Tamandua tetradactyla (Xenarthra, Pilosa): injuries to the locomotor system and first case report of osteomyelitis in anteaters. 61
31023313 2019
22
Inflammatory variant of pachydermoperiostosis responding to methotrexate: a report of two cases. 61
31007935 2019
23
Voriconazole-Induced Periostitis After Allogeneic Stem Cell Transplantation. 61
30516686 2019
24
Spectrum of Voriconazole-Induced Periostitis With Review of the Differential Diagnosis. 61
30403528 2019
25
Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy. 61
31467740 2019
26
Paranasal sinus cysts in the horse: Complications related to their presence and surgical treatment in 37 cases. 61
29679404 2019
27
Use of Erbium Laser in the Treatment of a Patient with Acute Purulent Periostitis and a Resistant Form of Primary Immune Thrombocytopenia. 61
31531248 2019
28
Florid reactive periostitis of the metacarpal bone: a case of resolution without resection. 61
30114991 2018
29
Magnetic Resonance Imaging-Based Grading of Cartilaginous Bone Tumors: Added Value of Quantitative Texture Analysis. 61
29863601 2018
30
A vexing case of bone pain in a renal transplant recipient: Voriconazole-induced periostitis. 61
29873153 2018
31
Bone Scintigraphy in Poststreptococcal Periostitis With Dysproteinemia. 61
30036251 2018
32
Diffuse periostitis as the primary presenting radiological finding in an AML patient with disease relapse. 61
30108676 2018
33
Reactive Periostitis Due To Inhalant Abuse. 61
29660262 2018
34
LATE DIAGNOSIS OF CONGENITAL SYPHILIS: A RECURRING REALITY IN WOMEN AND CHILDREN HEALTH CARE IN BRAZIL. 61
30066818 2018
35
Unusual Manifestations of Secondary Syphilis: Case Presentations. 61
29989879 2018
36
Voriconazole-induced Severe Periostitis Deformans. 61
29866241 2018
37
A Case of Hypertrophic Pulmonary Osteoarthropathy in Both Upper and Lower Extremities: A Rare Involvement. 61
29889032 2018
38
Incomplete form of Primary Hypertrophic Osteoarthropathy (Touraine-Solente-Gole Syndrome) Masquerading as Polyartrhalgia Diagnosed in Technetium-99m-Methylene Diphosphonate Scintigraphy: An Interesting Case Report. 61
29643673 2018
39
[Goldboom's syndrome: prolonged febrile syndrome with dysproteinemia. Case report]. 61
29557628 2018
40
Correction to: Voriconazole-induced periostitis deformans: serial imaging in a patient with ANCA vasculitis. 61
29353405 2018
41
Complete resolution and remodeling of chronic recurrent multifocal osteomyelitis on MRI and radiographs. 61
29124297 2018
42
Chronic non-suppurative mandibular osteomyelitis with proliferative periostitis: A review. 61
29435520 2018
43
Identification of serum miR-124 as a biomarker for diagnosis and prognosis in osteosarcoma. 61
29125481 2018
44
Voriconazole-induced periostitis deformans: serial imaging in a patient with ANCA vasculitis. 61
28866833 2018
45
Leg Pain From Periostitis as the First Clinical Manifestation of Large-Vessel Vasculitis: A Case Report. 61
28684264 2018
46
Rapid response to clinical symptoms in early psoriatic onycho-pachydermo-periostitis treated with infliximab. 61
28660645 2018
47
Proliferative Periostitis in a Pediatric Patient. 61
29663971 2018
48
Hypertrophic pulmonary osteoarthropathy: an unusual presentation. 61
31431958 2018
49
Pachydermoperiostosis in a Patient with Crohn's Disease: Treatment and Literature Review. 61
29398756 2018
50
Chronic non-suppurative mandibular osteomyelitis with proliferative periostitis: A review. 61
29399678 2018

Variations for Periostitis

Expression for Periostitis

Search GEO for disease gene expression data for Periostitis.

Pathways for Periostitis

Pathways related to Periostitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.7 TNFRSF11B TNFRSF11A SQSTM1 PSTPIP1 IL36B IL1RN
2
Show member pathways
13.25 TNFRSF11B TNFRSF11A IL36RN IL36B IL1RN IL1RL2
3
Show member pathways
12.39 TNFRSF11B TNFRSF11A SQSTM1 IL36B IL1RN IL1RL2
4
Show member pathways
12.07 IL36RN IL36B IL1RN IL1RL2 IL1F10 IL1A
5 11.56 TNFRSF11B TNFRSF11A SQSTM1 IL1A
6 11.55 TNFRSF11A IL1A IL11
7 11.15 TNFRSF11B TNFRSF11A IL1A
8 10.64 TNFRSF11B TNFRSF11A

GO Terms for Periostitis

Cellular components related to Periostitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 TNFRSF11B IL36RN IL36B IL1RN IL1F10 IL1A
2 extracellular space GO:0005615 9.23 TNFRSF11B IL36RN IL36B IL1RN IL1F10 IL1A

Biological processes related to Periostitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.88 SQSTM1 PSTPIP1 IL36RN IL36B IL1RL2
2 innate immune response GO:0045087 9.8 PSTPIP1 IL36RN IL36B IL1RL2 CRP
3 immune response GO:0006955 9.77 IL36RN IL36B IL1RN IL1F10 IL1A
4 cytokine-mediated signaling pathway GO:0019221 9.7 IL36RN IL36B IL1RN IL1RL2 IL1F10 IL1A
5 cellular response to lipopolysaccharide GO:0071222 9.62 IL36RN IL36B IL1F10 IL1A
6 tumor necrosis factor-mediated signaling pathway GO:0033209 9.61 TNFRSF11B TNFRSF11A CARD14
7 interleukin-1-mediated signaling pathway GO:0070498 9.56 SQSTM1 IL1RN IL1RL2 IL1A
8 inflammatory response GO:0006954 9.56 PSTPIP1 IL36RN IL36B IL1RN IL1RL2 IL1F10
9 positive regulation of T cell differentiation GO:0045582 9.46 IL36B IL1RL2
10 inflammatory response to antigenic stimulus GO:0002437 9.02 IL36RN IL36B IL1RN IL1F10 IL1A

Molecular functions related to Periostitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.5 TNFRSF11B IL36RN IL36B IL1RN IL1F10 IL1A
2 interleukin-1 receptor antagonist activity GO:0005152 9.16 IL36RN IL1RN
3 interleukin-1 receptor binding GO:0005149 9.02 IL36RN IL36B IL1RN IL1F10 IL1A

Sources for Periostitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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