MCID: PRP018
MIFTS: 21

Peripheral Nerve Schwannoma

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Peripheral Nerve Schwannoma

MalaCards integrated aliases for Peripheral Nerve Schwannoma:

Name: Peripheral Nerve Schwannoma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:956
NCIt 49 C41430
UMLS 71 C1519001

Summaries for Peripheral Nerve Schwannoma

MalaCards based summary: Peripheral Nerve Schwannoma is related to neurilemmoma and neurofibromatosis, type ii. An important gene associated with Peripheral Nerve Schwannoma is SERPINA3 (Serpin Family A Member 3). Related phenotypes are Increased proliferation and hematopoietic system

Related Diseases for Peripheral Nerve Schwannoma

Diseases related to Peripheral Nerve Schwannoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 neurilemmoma 30.0 SMARCB1 SERPINA3 NF2 NF1 LZTR1
2 neurofibromatosis, type ii 29.7 SMARCB1 NF2 NF1 LZTR1
3 neurofibromatosis 29.7 SMARCB1 NF2 NF1 LZTR1
4 acoustic neuroma 29.7 SMARCB1 NF2 NF1 LZTR1
5 peripheral nervous system disease 29.4 SMARCB1 SERPINA3 NF2 NF1
6 proliferative fasciitis 10.2 SMARCB1 SERPINA3
7 chondroid chordoma 10.1 SMARCB1 SERPINA3
8 posterior pituitary gland neoplasm 10.1 SMARCB1 NF2
9 fibroma 10.1 SERPINA3 NF1
10 childhood meningioma 10.1 SMARCB1 NF2
11 pineal region meningioma 10.1 SMARCB1 NF2
12 cerebral falx meningioma 10.1 SMARCB1 NF2
13 parasagittal meningioma 10.1 SMARCB1 NF2
14 cerebral convexity meningioma 10.1 SMARCB1 NF2
15 schwannomatosis 1 10.1 SMARCB1 NF2
16 sarcomatoid squamous cell skin carcinoma 10.1 SMARCB1 SERPINA3
17 olfactory groove meningioma 10.1 SMARCB1 NF2
18 cerebellopontine angle tumor 10.1 SMARCB1 NF2
19 anterior cranial fossa meningioma 10.1 SMARCB1 NF2
20 chordoid meningioma 10.1 SMARCB1 NF2
21 kidney rhabdoid cancer 10.1 SMARCB1 SERPINA3
22 brain meningioma 10.1 SMARCB1 NF2
23 transitional meningioma 10.1 SMARCB1 NF2
24 melanotic neurilemmoma 10.1 SMARCB1 NF2
25 rhabdoid meningioma 10.1 SMARCB1 NF2
26 spinal cord ependymoma 10.1 SMARCB1 NF2
27 epithelioid neurofibroma 10.1 NF2 NF1
28 clear cell meningioma 10.1 SMARCB1 NF2
29 fibrous meningioma 10.1 SMARCB1 NF2
30 neurilemmoma of the fifth cranial nerve 10.1 NF2 NF1
31 small intestine leiomyoma 10.1 NF2 NF1
32 trigeminal nerve neoplasm 10.1 NF2 NF1
33 spinal cord astrocytoma 10.1 NF2 NF1
34 epidural spinal canal neoplasm 10.1 NF2 NF1
35 cerebellar astrocytoma 10.1 SERPINA3 NF1
36 anaplastic ependymoma 10.1 SMARCB1 NF2
37 orbital cancer 10.1 NF2 NF1
38 oto-palatal-digital syndrome 10.1
39 non-langerhans-cell histiocytosis 10.1 SERPINA3 NF1
40 polyp of corpus uteri 10.1 NF2 NF1
41 rete ovarii adenoma 10.1 NF2 NF1
42 tenosynovial giant cell tumor 10.1 SERPINA3 IL34
43 pleomorphic xanthoastrocytoma 10.1 SERPINA3 NF1
44 rete ovarii benign neoplasm 10.1 NF2 NF1
45 malignant spindle cell melanoma 10.1 SERPINA3 NF1
46 high grade ependymoma 10.1 SMARCB1 NF2
47 giant cell reparative granuloma 10.1 SERPINA3 NF1
48 ossifying fibroma 10.1 SERPINA3 NF1
49 optic nerve glioma 10.1 NF2 NF1
50 cerebral ventricle cancer 10.1 SMARCB1 NF2

Graphical network of the top 20 diseases related to Peripheral Nerve Schwannoma:



Diseases related to Peripheral Nerve Schwannoma

Symptoms & Phenotypes for Peripheral Nerve Schwannoma

GenomeRNAi Phenotypes related to Peripheral Nerve Schwannoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Peripheral Nerve Schwannoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.17 IL34 LZTR1 NF1 PHYH SERPINA3 SMARCB1

Drugs & Therapeutics for Peripheral Nerve Schwannoma

Search Clinical Trials, NIH Clinical Center for Peripheral Nerve Schwannoma

Genetic Tests for Peripheral Nerve Schwannoma

Anatomical Context for Peripheral Nerve Schwannoma

Publications for Peripheral Nerve Schwannoma

Articles related to Peripheral Nerve Schwannoma:

(show all 18)
# Title Authors PMID Year
1
Diagnostic accuracy of multiparametric ultrasound for peripheral nerve schwannoma. 62
36071627 2022
2
Clinical results after surgical resection of benign solitary schwannomas: A review of 150 cases. 62
35477039 2022
3
Epineural glomus tumor of the posterior interosseous nerve: Case report. 62
31917057 2020
4
The effect of ozone injection within a common peroneal nerve schwannoma: A mistreatment due to a misdiagnosis. 62
33365176 2020
5
Extracapsular dissection in peripheral nerve schwannoma surgery using bright light and fluorescein sodium visualization: case series. 62
31679103 2019
6
[Surgical Technique for Peripheral Nerve Schwannoma Resection]. 62
31874942 2019
7
Erdheim-Chester disease mimicking lumbar nerve schwannoma: case report and literature review. 62
31700688 2019
8
Analysis of Peripheral Nerve Schwannoma Pseudocapsule. 62
30114537 2018
9
Utility of intraoperative monitoring with motor-evoked potential during the surgical enucleation of peripheral nerve schwannoma. 62
29844829 2018
10
Peripheral Nerve Schwannoma: A Review of Varying Clinical Presentations and Imaging Findings. 62
28237565 2017
11
A Vascular Malformation Presenting as a Peripheral Nerve Sheath Tumor. 62
28077959 2016
12
Commentary on: 'Comparison of outcomes of peripheral nerve schwannoma excision in neurofibromatosis type 2 patients and non-neurofibromatosis type 2 patients: A case control study'. 62
26070489 2015
13
Comparison of outcomes of peripheral nerve schwannoma excision in neurofibromatosis type 2 patients and non-neurofibromatosis type 2 patients: A case control study. 62
26139580 2015
14
Preoperative localization of spinal and peripheral pathologies for surgery by computed tomography-guided placement of a specialized needle system. 62
20190662 2010
15
Fluid-fluid level in peripheral nerve schwannoma: report of a case with histological correlation. 62
19411036 2009
16
Peripheral nerve schwannoma: two cases exhibiting increased FDG uptake in early and delayed PET imaging. 62
15480645 2005
17
Peripheral nerve schwannoma preoperatively diagnosed by sonography: report of three cases and discussion. 62
9248799 1997
18
Assessing sensory involvement in lower limb nerve lesions using somatosensory evoked potential techniques. 62
16758575 1985

Variations for Peripheral Nerve Schwannoma

Expression for Peripheral Nerve Schwannoma

Search GEO for disease gene expression data for Peripheral Nerve Schwannoma.

Pathways for Peripheral Nerve Schwannoma

GO Terms for Peripheral Nerve Schwannoma

Biological processes related to Peripheral Nerve Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin cytoskeleton organization GO:0030036 9.8 SPTBN2 NF2 NF1
2 negative regulation of cell-matrix adhesion GO:0001953 9.46 NF2 NF1
3 negative regulation of Ras protein signal transduction GO:0046580 9.43 NF1 LZTR1
4 negative regulation of Schwann cell proliferation GO:0010626 9.26 NF2 NF1
5 Schwann cell proliferation GO:0014010 8.92 NF2 NF1

Sources for Peripheral Nerve Schwannoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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