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MCID: PRP024
MIFTS: 23

Peripheral Osteosarcoma

Categories: Bone diseases, Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Peripheral Osteosarcoma

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MalaCards integrated aliases for Peripheral Osteosarcoma:

Name: Peripheral Osteosarcoma 12 15
Bone Surface Osteosarcoma 71
Surface Osteosarcoma 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Bone diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3374
NCIt 49 C7134
UMLS 71 C1332591
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Summaries for Peripheral Osteosarcoma

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MalaCards based summary : Peripheral Osteosarcoma, also known as bone surface osteosarcoma, is related to periosteal osteogenic sarcoma and bone osteosarcoma. An important gene associated with Peripheral Osteosarcoma is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways is Oncogene Induced Senescence. Affiliated tissues include bone, appendix and lung.

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Related Diseases for Peripheral Osteosarcoma

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Diseases related to Peripheral Osteosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 periosteal osteogenic sarcoma 30.7 SATB2 MDM2
2 bone osteosarcoma 29.3 SNRNP25 SATB2 MDM2 COPS3 CDK4
3 juxtacortical osteosarcoma 25.5 VGLL3 SNRNP25 SATB2 RBM4B MDM2 KCNMB4
4 osteogenic sarcoma 10.5
5 ring chromosome 7 10.4 MDM2 CDK4
6 ring chromosome 10.4 MDM2 CDK4
7 mediastinum liposarcoma 10.4 MDM2 CDK4
8 gastric liposarcoma 10.4 MDM2 CDK4
9 diffuse lipomatosis 10.4 MDM2 CDK4
10 undifferentiated embryonal sarcoma of the liver 10.4 MDM2 CDK4
11 embryonal sarcoma 10.4 MDM2 CDK4
12 spindle cell liposarcoma 10.4 MDM2 CDK4
13 pediatric liposarcoma 10.4 MDM2 CDK4
14 infiltrating lipoma 10.4 MDM2 CDK4
15 lipoblastoma 10.4 MDM2 CDK4
16 mediastinum sarcoma 10.4 MDM2 CDK4
17 liposarcoma of bone 10.4 MDM2 CDK4
18 pancreas sarcoma 10.4 MDM2 CDK4
19 adult liposarcoma 10.3 MDM2 CDK4
20 telangiectatic osteogenic sarcoma 10.3 MDM2 COPS3
21 paratesticular lipoma 10.3 MDM2 CDK4
22 lipoma of spermatic cord 10.3 MDM2 CDK4
23 extraosseous osteosarcoma 10.3 MDM2 CDK4
24 mixed liposarcoma 10.3 MDM2 CDK4
25 retroperitoneal sarcoma 10.3 MDM2 CDK4
26 infiltrating angiolipoma 10.3 MDM2 CDK4
27 parameningeal embryonal rhabdomyosarcoma 10.3 MDM2 CDK4
28 dedifferentiated liposarcoma 10.2 MDM2 CDK4
29 appendix adenocarcinoma 10.2 SATB2 GNAS
30 myositis ossificans 10.2 SATB2 MDM2
31 cellular myxoid liposarcoma 10.2 MDM2 CDK4
32 connective tissue benign neoplasm 10.2 MDM2 GNAS CDK4
33 appendix disease 10.2 SATB2 GNAS
34 ischemic fasciitis 10.1 MDM2 CDK4
35 pleomorphic lipoma 10.1 TSPAN31 MDM2 CDK4
36 well-differentiated liposarcoma 10.1 TSPAN31 MDM2 CDK4
37 liposarcoma 10.1 TSPAN31 MDM2 CDK4
38 appendix cancer 10.1 SATB2 GNAS
39 familial retinoblastoma 10.1 MDM2 CDK4
40 lipomatosis, multiple 10.1 TSPAN31 MDM2 CDK4
41 inflammatory mfh 10.0 VGLL3 MDM2 CDK4
42 pleomorphic liposarcoma 10.0 MDM2 CDK4
43 conventional central osteosarcoma 9.9 SNRNP25 SATB2 MDM2 COPS3
44 ossifying fibroma 9.8 MDM2 GNAS
45 aneurysmal bone cysts 9.8
46 myelodysplastic syndrome 9.8
47 secondary progressive multiple sclerosis 9.8
48 colorectal adenocarcinoma 9.8
49 synostosis 9.8
50 exostosis 9.8

Graphical network of the top 20 diseases related to Peripheral Osteosarcoma:



Diseases related to Peripheral Osteosarcoma
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Symptoms & Phenotypes for Peripheral Osteosarcoma

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Drugs & Therapeutics for Peripheral Osteosarcoma

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Search Clinical Trials , NIH Clinical Center for Peripheral Osteosarcoma

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Genetic Tests for Peripheral Osteosarcoma

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Anatomical Context for Peripheral Osteosarcoma

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MalaCards organs/tissues related to Peripheral Osteosarcoma:

40
Bone, Appendix, Lung, Liver, Pancreas
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Publications for Peripheral Osteosarcoma

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Articles related to Peripheral Osteosarcoma:

(show all 40)
# Title Authors PMID Year
1
Low-Grade Surface Osteosarcoma of the Temporal Bone in Paediatric Patients: A Case Report and Literature Review. 61
31263376 2019
2
Triple primary malignancies of surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer as a second primary cancer detected by PET2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography: A case report. 61
29928362 2018
3
Surface osteosarcoma: Clinical features and therapeutic implications. 61
26730360 2015
4
High-grade surface osteosarcoma of the rib - a case report. 61
26277177 2015
5
Osteoma of long bone: an expanding spectrum of imaging findings. 61
25380570 2015
6
Post-traumatic heterotopic ossification of distal tibiofibular syndesmosis mimicking a surface osteosarcoma. 61
24034551 2013
7
A popliteal giant synovial osteochondroma mimicking a parosteal osteosarcoma. 61
24066980 2013
8
Novel oncologic, surgical, and prosthetic treatment of high-grade surface osteosarcoma, osteoblastic mandible type. 61
23298800 2013
9
Local recurrence of a parosteal osteosarcoma 21 years after incomplete resection. 61
22059909 2011
10
Periosteal osteoblastoma: Multimodal imaging of a rare neoplasm. 61
27307837 2009
11
High-grade surface osteosarcoma: a review of 25 cases from the Rizzoli Institute. 61
18300258 2008
12
High-grade surface osteosarcoma - chondroblastic type. 61
18356791 2007
13
High-grade surface osteosarcoma of the hand. 61
17410355 2007
14
[An aggressive chondroblastoma mimicking paraosteal osteosarcoma]. 61
18078282 2007
15
Hemicortical excision for low-grade selected surface sarcomas of bone. 61
17415008 2007
16
Surface osteosarcoma: 2 case reports. 61
16935183 2006
17
Pediatric surface osteosarcoma: clinical, pathologic, and radiologic features. 61
16123997 2006
18
Report of four cases with high-grade surface osteosarcoma. 61
16533804 2006
19
Pulmonary nodules in osteosarcoma patients: differential diagnosis of central venous catheter-related infections in the lungs. 61
16671377 2006
20
Skull osteosarcoma: illustrated review. 61
15340877 2004
21
Periosteal osteoblastoma of the distal femur. 61
14714148 2004
22
Multiple primary malignancies in osteosarcoma patients. Incidence and predictive value of osteosarcoma subtype for cancer syndromes related with osteosarcoma. 61
12891382 2003
23
High-grade surface osteosarcoma in a dog. 61
12779173 2003
24
Dedifferentiated parosteal osteosarcoma with rhabdomyosarcomatous differentiation. 61
10525797 1999
25
Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases. 61
10561354 1999
26
High grade surface osteosarcoma: a clinicopathologic study of 46 cases. 61
10091787 1999
27
Expression of transforming growth factor beta isoforms in osteosarcoma variants: association of TGF beta 1 with high-grade osteosarcomas. 61
9771482 1998
28
Osteosarcoma of the larynx. 61
9439392 1998
29
SAS is amplified predominantly in surface osteosarcoma. 61
8893761 1996
30
High-grade surface osteosarcoma of the humerus. 61
8545652 1995
31
Case report: primary high grade surface osteosarcoma. 61
7889716 1995
32
New aspects in the treatment of bone sarcomas. 61
8587837 1994
33
High malignant surface osteosarcoma arising at the site of a previously treated aneurysmal bone cyst. 61
8491756 1993
34
Case report 795. High-grade surface osteosarcoma of the radius. 61
8372370 1993
35
"Tumoral" enthesopathy: a juxtacortical osteosarcoma simulation. 61
1765994 1991
36
Surface osteosarcoma. 61
1884533 1991
37
Osteosarcomas arising on the surfaces of long bones. 61
3281953 1988
38
High-grade surface osteosarcoma of the left ilium. A case report and review of the literature. 61
3164569 1988
39
Juxtacortical osteosarcoma: a radiologic and histologic spectrum. 61
3860961 1985
40
Case report 258. High-grade "surface" osteosarcoma arising from femoral shaft. 61
6584982 1984
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Variations for Peripheral Osteosarcoma

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Expression for Peripheral Osteosarcoma

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Search GEO for disease gene expression data for Peripheral Osteosarcoma.
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Pathways for Peripheral Osteosarcoma

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Pathways related to Peripheral Osteosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Oncogene Induced Senescence 65
10.13 MDM2 CDK4
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GO Terms for Peripheral Osteosarcoma

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Biological processes related to Peripheral Osteosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell cycle GO:0045787 9.16 MDM2 CDK4
2 cellular response to organic substance GO:0071310 8.96 SATB2 MDM2
3 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4
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Sources for Peripheral Osteosarcoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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