Peripheral Resistance to Thyroid Hormones disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Peripheral Resistance to Thyroid Hormones

MalaCards integrated aliases for Peripheral Resistance to Thyroid Hormones:

Name: Peripheral Resistance to Thyroid Hormones ⁵²

Obsolete: Peripheral Resistance to Thyroid Hormones ⁵² ⁵⁸

Characteristics:

Orphanet epidemiological data:

⁵⁸

obsolete: peripheral resistance to thyroid hormones
Inheritance: Autosomal dominant; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Orphanet ⁵⁸ ORPHA97927

SNOMED-CT via HPO ⁶⁸ 14760008 18165001 225595004 more

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Summaries for Peripheral Resistance to Thyroid Hormones

MalaCards based summary : Peripheral Resistance to Thyroid Hormones, also known as obsolete: peripheral resistance to thyroid hormones, is related to thyroid hormone resistance, generalized, autosomal dominant and hyperthyroidism. Affiliated tissues include thyroid, testes and pituitary, and related phenotypes are sleep disturbance and constipation

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Related Diseases for Peripheral Resistance to Thyroid Hormones

Diseases related to Peripheral Resistance to Thyroid Hormones via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)

#	Related Disease	Score
1	thyroid hormone resistance, generalized, autosomal dominant	11.9
2	hyperthyroidism	10.3
3	goiter	10.2
4	graves' disease	10.2
5	thyroid hormone resistance, generalized, autosomal recessive	10.1
6	hashimoto thyroiditis	9.9
7	paranoid schizophrenia	9.9
8	hypothyroidism	9.9
9	hyperthyroxinemia	9.9
10	mood disorder	9.9
11	thyroiditis	9.9
12	granulocytopenia	9.9

Graphical network of the top 20 diseases related to Peripheral Resistance to Thyroid Hormones:

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Symptoms & Phenotypes for Peripheral Resistance to Thyroid Hormones

Human phenotypes related to Peripheral Resistance to Thyroid Hormones:

³¹ (show all 11)

#	Description	HPO Frequency	HPO Source Accession
1	sleep disturbance ³¹	hallmark (90%)	HP:0002360
2	constipation ³¹	hallmark (90%)	HP:0002019
3	hypothyroidism ³¹	hallmark (90%)	HP:0000821
4	muscular hypotonia ³¹	hallmark (90%)	HP:0001252
5	macroglossia ³¹	hallmark (90%)	HP:0000158
6	coarse facial features ³¹	hallmark (90%)	HP:0000280
7	umbilical hernia ³¹	hallmark (90%)	HP:0001537
8	feeding difficulties ³¹	hallmark (90%)	HP:0011968
9	jaundice ³¹	hallmark (90%)	HP:0000952
10	large fontanelles ³¹	hallmark (90%)	HP:0000239
11	abdominal distention ³¹	hallmark (90%)	HP:0003270

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Drugs & Therapeutics for Peripheral Resistance to Thyroid Hormones

Search Clinical Trials , NIH Clinical Center for Peripheral Resistance to Thyroid Hormones

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Genetic Tests for Peripheral Resistance to Thyroid Hormones

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Anatomical Context for Peripheral Resistance to Thyroid Hormones

MalaCards organs/tissues related to Peripheral Resistance to Thyroid Hormones:

⁴⁰

Thyroid, Testes, Pituitary

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Publications for Peripheral Resistance to Thyroid Hormones

Articles related to Peripheral Resistance to Thyroid Hormones:

(show all 22)

#	Title	Authors	PMID	Year
1	Thyroid hormone resistance syndrome due to mutations in the thyroid hormone receptor α gene (THRA). ⁶	Tylki-Szymanska A...Chrzanowska KH	25670821	2015
2	Clinical phenotype and mutant TRα1. ⁶	van Mullem A...Visser TJ	22494134	2012
3	A mutation in the thyroid hormone receptor alpha gene. ⁶	Bochukova E...Chatterjee K	22168587	2012
4	A Rare Case of Partial Peripheral Thyroid Hormone Resistance Due to a Point Mutation in the Membrane Integrin Α(V)Β(3) and Concomitant Hashimoto`s Thyroiditis. ⁶¹	Savovska M...Manevska N	31406543	2019
5	Thyroid hormones and the central nervous system of mammals (Review). ⁶¹	Di Liegro I	21479409	2008
6	[Hypothyroidism. Emphasis on clinical aspects or laboratory tests? Report about well known facts which, however, can be doubted]. ⁶¹	Rootwelt K	1998184	1991
7	Familial generalized resistance to thyroid hormones: report of three kindreds and correlation of patterns of affected tissues with the binding of [125I] triiodothyronine to fibroblast nuclei. ⁶¹	Magner JA...Weintraub BD	3571851	1986
8	[Hyperthyroxinemia without hyperthyroidism]. ⁶¹	Rongen-Westerlaken C...van Gelderen HH	3085279	1986
9	[Diagnosis of peripheral thyroid hormone effect using sex hormone-binding globulin (SHBG) and systolic time intervals (STI)]. ⁶¹	Wakonig P...Eber O	3766084	1986
10	Peripheral resistance to thyroid hormones. ⁶¹	Connors MH...Kollipara S	3990382	1985
11	A new and distinctive albumin variant with increased affinities for both triiodothyronines and causing hyperthyroxinaemia. ⁶¹	Lalloz MR...Himsworth RL	3987070	1985
12	Familial euthyroid hyperthyroxinemia secondary to pituitary and peripheral resistance to thyroid hormones. ⁶¹	Gharib H...Klee GG	2981377	1985
13	Peripheral resistance to thyroid hormones. ⁶¹		6723083	1984
14	Partial peripheral resistance to thyroid hormones, a post-receptor defect? ⁶¹	Lamberg BA...Bernal J	6096250	1984
15	[Goiter in childhood]. ⁶¹	Mussa GC	6689630	1983
16	Euthyroid hyperthyroxinemia. ⁶¹	Borst GC...Burman KD	6187257	1983
17	Defective thyroid hormone action in fibroblasts cultured from subjects with the syndrome of resistance to thyroid hormones. ⁶¹	Chait A...Kenny M	7037814	1982
18	Triiodothyronine binding to lymphocyte nuclei and plasma cyclic AMP response to intravenous glucagon in patients with peripheral resistance to thyroid hormones. ⁶¹	Elewaut A...Vermeulen A	6261508	1981
19	Peripheral insensitivity to thyroid hormones in a euthyroid girl with goitre. ⁶¹	Maenpaa J...Liewendahl K	6247978	1980
20	[Congenital goiter with partial peripheral resistance to thyroid hormones or pseudo-hyperthyroidism syndrome]. ⁶¹	David L...Francois R	503718	1979
21	Familial partial peripheral resistance to thyroid hormones. ⁶¹	Lamberg BA...Evered DC	75651	1978
22	Congenital euthyroid goitre and partial peripheral resistance to thyroid hormones. ⁶¹	Lamberg BA	4123403	1973

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Genes for Peripheral Resistance to Thyroid Hormones

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Variations for Peripheral Resistance to Thyroid Hormones

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Expression for Peripheral Resistance to Thyroid Hormones

Search GEO for disease gene expression data for Peripheral Resistance to Thyroid Hormones.

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Pathways for Peripheral Resistance to Thyroid Hormones

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GO Terms for Peripheral Resistance to Thyroid Hormones

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