MCID: PRT034
MIFTS: 26

Peritoneal Serous Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Peritoneal Serous Adenocarcinoma

MalaCards integrated aliases for Peritoneal Serous Adenocarcinoma:

Name: Peritoneal Serous Adenocarcinoma 12 15
Primary Peritoneal Serous Adenocarcinoma 12 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4901
NCIt 50 C40023
UMLS 70 C1514429

Summaries for Peritoneal Serous Adenocarcinoma

MalaCards based summary : Peritoneal Serous Adenocarcinoma, also known as primary peritoneal serous adenocarcinoma, is related to primary peritoneal carcinoma and testicular granulosa cell tumor. An important gene associated with Peritoneal Serous Adenocarcinoma is CALB2 (Calbindin 2), and among its related pathways/superpathways is Cytoskeletal Signaling. Affiliated tissues include appendix, and related phenotypes are cardiovascular system and cellular

Related Diseases for Peritoneal Serous Adenocarcinoma

Diseases related to Peritoneal Serous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 488)
# Related Disease Score Top Affiliating Genes
1 primary peritoneal carcinoma 31.5 TP53 PGR
2 testicular granulosa cell tumor 10.4 WT1 CALB2
3 malignant epithelial mesothelioma 10.4 PTGER4 CALB2
4 rete testis adenoma 10.4 PAX8 CALB2
5 testicular fibroma 10.4 WT1 CALB2
6 hobnail hemangioma 10.4 WT1 PIP
7 colon leiomyosarcoma 10.4 WT1 PAX8
8 lymphohistiocytoid mesothelioma 10.4 PTGER4 CALB2
9 malignant biphasic mesothelioma 10.4 WT1 CALB2
10 ceruminoma 10.4 PIP KRT7
11 primary congenital hypothyroidism 10.4 PAX8 NKX2-1
12 epithelial predominant wilms' tumor 10.4 WT1 KRT7
13 microinvasive cervical squamous cell carcinoma 10.4 WT1 KRT7
14 anus basaloid carcinoma 10.4 PTGER4 KRT7
15 ovarian mixed germ cell neoplasm 10.4 WT1 PAX8
16 malignant acrospiroma 10.4 PIP KRT7
17 nephrogenic adenofibroma 10.4 WT1 KRT7
18 ceruminous adenocarcinoma 10.4 PIP KRT7
19 cutaneous mucoepidermoid carcinoma 10.4 PIP KRT7
20 vulval paget's disease 10.4 PIP KRT7
21 eccrine adenocarcinoma 10.3 PIP KRT7
22 juvenile type testicular granulosa cell tumor 10.3 WT1 CALB2
23 wolffian duct adenoma 10.3 PAX8 KRT7
24 ovarian gonadoblastoma 10.3 WT1 CALB2
25 lung sarcomatoid carcinoma 10.3 NKX2-1 CALB2
26 lung sarcoma 10.3 NKX2-1 CALB2
27 thyroid malformation 10.3 PAX8 NKX2-1
28 renal pelvis adenocarcinoma 10.3 PAX8 KRT7
29 athyreosis 10.3 PAX8 NKX2-1
30 urethral diverticulum 10.3 PAX8 KRT7
31 erysipeloid 10.3 PIP KRT7
32 larynx sarcoma 10.3 NKX2-1 EPCAM
33 hidrocystoma 10.3 PIP KRT7
34 dacryocystocele 10.3 PIP KRT7
35 chronic inflammation of lacrimal passage 10.3 PIP KRT7
36 follicular infundibulum tumor 10.3 PTGER4 KRT17
37 inverted follicular keratosis 10.3 PTGER4 KRT17
38 myoblastoma 10.3 SYP CALB2
39 clear cell cystadenofibroma 10.3 TP53 CALB2
40 epididymal neoplasm 10.3 WT1 KRT7 CALB2
41 tinea cruris 10.3 PIP KRT7
42 sarcomatoid mesothelioma 10.3 WT1 NKX2-1 CALB2
43 ovarian sex-cord stromal tumor 10.3 WT1 KRT7 CALB2
44 middle ear carcinoma 10.3 WT1 KRT7
45 bladder leiomyoma 10.3 KRT7 CALB2
46 subungual glomus tumor 10.3 SYP PIP
47 sarcomatous intrahepatic cholangiocarcinoma 10.3 NKX2-1 KRT7
48 synovium cancer 10.3 WT1 KRT7 CALB2
49 primary hepatic neuroendocrine carcinoma 10.3 SYP CHGA
50 esophageal neuroendocrine tumor 10.3 SYP CHGA

Graphical network of the top 20 diseases related to Peritoneal Serous Adenocarcinoma:



Diseases related to Peritoneal Serous Adenocarcinoma

Symptoms & Phenotypes for Peritoneal Serous Adenocarcinoma

MGI Mouse Phenotypes related to Peritoneal Serous Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 CDX2 CHGA CLDN4 EPCAM NKX2-1 PAX8
2 cellular MP:0005384 10.1 CDX2 CLDN4 EPCAM KRT17 KRT7 NKX2-1
3 endocrine/exocrine gland MP:0005379 9.91 CDX2 CHGA EPCAM NKX2-1 PAX8 PGR
4 neoplasm MP:0002006 9.63 CDX2 NKX2-1 PGR PTGER4 TP53 WT1
5 no phenotypic analysis MP:0003012 9.56 CHGA EPCAM KRT17 NKX2-1 PAX8 PGR
6 normal MP:0002873 9.32 CALB2 CDX2 CLDN4 NKX2-1 PAX8 PGR

Drugs & Therapeutics for Peritoneal Serous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Peritoneal Serous Adenocarcinoma

Genetic Tests for Peritoneal Serous Adenocarcinoma

Anatomical Context for Peritoneal Serous Adenocarcinoma

MalaCards organs/tissues related to Peritoneal Serous Adenocarcinoma:

40
Appendix

Publications for Peritoneal Serous Adenocarcinoma

Articles related to Peritoneal Serous Adenocarcinoma:

# Title Authors PMID Year
1
Small orangiophilic squamous-like cells: an underrecognized and useful morphological feature for the diagnosis of malignant mesothelioma in pleural effusion cytology. 61
23983174 2014
2
Mucosal carcinoma of the fallopian tube coexists with ovarian cancer of serous subtype only: a study of Japanese cases. 61
20872013 2010
3
Mixed carcinoid and adenocarcinoma of the appendix: report of 4 cases with immunohistochemical studies and a review of the literature. 61
15551743 2004
4
Primary peritoneal psammocarcinoma: A case presenting with an upper abdominal mass and elevated CA-125. 61
10329057 1999
5
Primary neoplasia of the female peritoneum. 61
8406381 1993

Variations for Peritoneal Serous Adenocarcinoma

Expression for Peritoneal Serous Adenocarcinoma

Search GEO for disease gene expression data for Peritoneal Serous Adenocarcinoma.

Pathways for Peritoneal Serous Adenocarcinoma

Pathways related to Peritoneal Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 KRT7 KRT20 KRT17 EPCAM

GO Terms for Peritoneal Serous Adenocarcinoma

Biological processes related to Peritoneal Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.77 WT1 TP53 PAX8 NKX2-1 CDX2
2 positive regulation of transcription by RNA polymerase II GO:0045944 9.73 WT1 TP53 PGR PAX8 NKX2-1 EPCAM
3 cornification GO:0070268 9.5 KRT7 KRT20 KRT17
4 cellular response to gonadotropin stimulus GO:0071371 9.16 WT1 PAX8
5 metanephric S-shaped body morphogenesis GO:0072284 8.96 WT1 PAX8
6 metanephric epithelium development GO:0072207 8.62 WT1 PAX8

Molecular functions related to Peritoneal Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.73 WT1 TP53 PGR PAX8 NKX2-1 CDX2
2 transcription regulatory region sequence-specific DNA binding GO:0000976 9.46 WT1 TP53 PAX8 NKX2-1
3 sequence-specific DNA binding GO:0043565 9.35 WT1 PGR PAX8 NKX2-1 CDX2
4 DNA-binding transcription factor activity GO:0003700 9.1 WT1 TP53 PGR PAX8 NKX2-1 CDX2

Sources for Peritoneal Serous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....