MCID: PRT017
MIFTS: 20

Peritoneal Serous Papillary Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Peritoneal Serous Papillary Adenocarcinoma

MalaCards integrated aliases for Peritoneal Serous Papillary Adenocarcinoma:

Name: Peritoneal Serous Papillary Adenocarcinoma 12 15
Primary Serous Papillary Carcinoma of Peritoneum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6228
NCIt 50 C7695
SNOMED-CT 68 15674004
UMLS 73 C1368918

Summaries for Peritoneal Serous Papillary Adenocarcinoma

MalaCards based summary : Peritoneal Serous Papillary Adenocarcinoma, also known as primary serous papillary carcinoma of peritoneum, is related to primary peritoneal serous/papillary carcinoma and adenocarcinoma. An important gene associated with Peritoneal Serous Papillary Adenocarcinoma is SFTPC (Surfactant Protein C), and among its related pathways/superpathways is Circadian rythm related genes. The drugs Doxorubicin and Atrasentan have been mentioned in the context of this disorder. Related phenotypes are cardiovascular system and neoplasm

Related Diseases for Peritoneal Serous Papillary Adenocarcinoma

Diseases related to Peritoneal Serous Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 primary peritoneal serous/papillary carcinoma 11.4
2 adenocarcinoma 10.1
3 papillary adenocarcinoma 10.1
4 peritonitis 10.1
5 nodular hidradenoma 9.8 PIP PTGER4
6 malignant epithelial mesothelioma 9.8 PTGER4 WT1
7 endosalpingiosis 9.7 PTGER4 WT1
8 peritoneum cancer 9.6 PTGER4 WT1
9 integumentary system cancer 9.6 PIP PTGER4
10 diaphragmatic hernia, congenital 9.3 SFTPC WT1
11 peritoneal serous adenocarcinoma 7.7 CLDN4 PIP PTGER4 SFTPC WT1

Graphical network of the top 20 diseases related to Peritoneal Serous Papillary Adenocarcinoma:



Diseases related to Peritoneal Serous Papillary Adenocarcinoma

Symptoms & Phenotypes for Peritoneal Serous Papillary Adenocarcinoma

MGI Mouse Phenotypes related to Peritoneal Serous Papillary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.35 WT1 CLDN4 PIP PTGER4 SFTPC
2 neoplasm MP:0002006 8.8 SFTPC WT1 PTGER4

Drugs & Therapeutics for Peritoneal Serous Papillary Adenocarcinoma

Drugs for Peritoneal Serous Papillary Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
2
Atrasentan Investigational Phase 2 173937-91-2, 195733-43-8 159594
3
Doxil Approved June 1999 Phase 2 31703
4 taxane Phase 2
5 Topoisomerase Inhibitors Phase 2
6 Endothelin Receptor Antagonists Phase 2
7 Anti-Bacterial Agents Phase 2
8 Antibiotics, Antitubercular Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ph II Atrasentan + DOXIL in Recurrent Ovarian/Fallopian/Peritoneal Serous Papillary Adenocarcinoma Terminated NCT00653328 Phase 2 atrasentan hydrochloride;doxil

Search NIH Clinical Center for Peritoneal Serous Papillary Adenocarcinoma

Genetic Tests for Peritoneal Serous Papillary Adenocarcinoma

Anatomical Context for Peritoneal Serous Papillary Adenocarcinoma

Publications for Peritoneal Serous Papillary Adenocarcinoma

Articles related to Peritoneal Serous Papillary Adenocarcinoma:

# Title Authors Year
1
Peritoneal serous papillary adenocarcinoma: report of four cases. ( 16258208 )
2005
2
Two cases of peritoneal serous papillary adenocarcinoma. ( 1721482 )
1991

Variations for Peritoneal Serous Papillary Adenocarcinoma

Expression for Peritoneal Serous Papillary Adenocarcinoma

Search GEO for disease gene expression data for Peritoneal Serous Papillary Adenocarcinoma.

Pathways for Peritoneal Serous Papillary Adenocarcinoma

Pathways related to Peritoneal Serous Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes

GO Terms for Peritoneal Serous Papillary Adenocarcinoma

Sources for Peritoneal Serous Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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