MCID: PRT017
MIFTS: 22

Peritoneal Serous Papillary Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Peritoneal Serous Papillary Adenocarcinoma

MalaCards integrated aliases for Peritoneal Serous Papillary Adenocarcinoma:

Name: Peritoneal Serous Papillary Adenocarcinoma 12 15
Primary Serous Papillary Carcinoma of Peritoneum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6228
NCIt 51 C7695
SNOMED-CT 69 15674004
UMLS 74 C1368918

Summaries for Peritoneal Serous Papillary Adenocarcinoma

MalaCards based summary : Peritoneal Serous Papillary Adenocarcinoma, also known as primary serous papillary carcinoma of peritoneum, is related to primary peritoneal serous/papillary carcinoma and adenocarcinoma. An important gene associated with Peritoneal Serous Papillary Adenocarcinoma is SFTPC (Surfactant Protein C), and among its related pathways/superpathways are Circadian rythm related genes and Cell adhesion molecules (CAMs). The drugs Doxorubicin and Atrasentan have been mentioned in the context of this disorder. Related phenotypes are Increased viability and cardiovascular system

Related Diseases for Peritoneal Serous Papillary Adenocarcinoma

Diseases related to Peritoneal Serous Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 primary peritoneal serous/papillary carcinoma 11.6
2 adenocarcinoma 10.2
3 papillary adenocarcinoma 10.2
4 malignant epithelial mesothelioma 9.9 PTGER4 WT1
5 benign mesothelioma 9.9 PTGER4 WT1
6 nodular hidradenoma 9.9 PIP PTGER4
7 endosalpingiosis 9.9 PTGER4 WT1
8 peritoneum cancer 9.8 PTGER4 WT1
9 diaphragmatic hernia, congenital 9.7 SFTPC WT1
10 peritoneal serous adenocarcinoma 8.9 CLDN4 PIP PTGER4 SFTPC WT1

Graphical network of the top 20 diseases related to Peritoneal Serous Papillary Adenocarcinoma:



Diseases related to Peritoneal Serous Papillary Adenocarcinoma

Symptoms & Phenotypes for Peritoneal Serous Papillary Adenocarcinoma

GenomeRNAi Phenotypes related to Peritoneal Serous Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 9.02 CLDN4 HLA-DQA1 PIP PTGER4 WT1

MGI Mouse Phenotypes related to Peritoneal Serous Papillary Adenocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.55 CLDN4 PIP PTGER4 SFTPC WT1
2 hematopoietic system MP:0005397 9.35 CLDN4 HLA-DQA1 PIP PTGER4 WT1
3 immune system MP:0005387 9.02 HLA-DQA1 PIP PTGER4 SFTPC WT1

Drugs & Therapeutics for Peritoneal Serous Papillary Adenocarcinoma

Drugs for Peritoneal Serous Papillary Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
2
Atrasentan Investigational Phase 2 173937-91-2, 195733-43-8 159594
3
Doxil Approved June 1999 Phase 2 31703
4 Bendamustine Hydrochloride Phase 2
5 Alkylating Agents Phase 2
6 Antineoplastic Agents, Alkylating Phase 2
7 Endothelin Receptor Antagonists Phase 2
8 taxane Phase 2
9 Antibiotics, Antitubercular Phase 2
10 Topoisomerase Inhibitors Phase 2
11 Endothelin A Receptor Antagonists Phase 2
12 Anti-Bacterial Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Open Trial of Bendamustine Hydrochloride in Women With Advanced Ovarian Cancer Completed NCT00867503 Phase 2 Bendamustine HCL
2 Ph II Atrasentan + DOXIL in Recurrent Ovarian/Fallopian/Peritoneal Serous Papillary Adenocarcinoma Terminated NCT00653328 Phase 2 atrasentan hydrochloride;doxil

Search NIH Clinical Center for Peritoneal Serous Papillary Adenocarcinoma

Genetic Tests for Peritoneal Serous Papillary Adenocarcinoma

Anatomical Context for Peritoneal Serous Papillary Adenocarcinoma

Publications for Peritoneal Serous Papillary Adenocarcinoma

Articles related to Peritoneal Serous Papillary Adenocarcinoma:

# Title Authors Year
1
Peritoneal serous papillary adenocarcinoma: report of four cases. ( 16258208 )
2005
2
Two cases of peritoneal serous papillary adenocarcinoma. ( 1721482 )
1991

Variations for Peritoneal Serous Papillary Adenocarcinoma

Expression for Peritoneal Serous Papillary Adenocarcinoma

Search GEO for disease gene expression data for Peritoneal Serous Papillary Adenocarcinoma.

Pathways for Peritoneal Serous Papillary Adenocarcinoma

Pathways related to Peritoneal Serous Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
2 10.79 CLDN4 HLA-DQA1

GO Terms for Peritoneal Serous Papillary Adenocarcinoma

Sources for Peritoneal Serous Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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