MCID: PRT017
MIFTS: 21

Peritoneal Serous Papillary Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Peritoneal Serous Papillary Adenocarcinoma

MalaCards integrated aliases for Peritoneal Serous Papillary Adenocarcinoma:

Name: Peritoneal Serous Papillary Adenocarcinoma 12 15
Primary Serous Papillary Carcinoma of Peritoneum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6228
NCIt 49 C7695
SNOMED-CT 67 15674004
UMLS 71 C1368918

Summaries for Peritoneal Serous Papillary Adenocarcinoma

MalaCards based summary : Peritoneal Serous Papillary Adenocarcinoma, also known as primary serous papillary carcinoma of peritoneum, is related to benign mesothelioma and primary peritoneal serous/papillary carcinoma. An important gene associated with Peritoneal Serous Papillary Adenocarcinoma is PIP (Prolactin Induced Protein), and among its related pathways/superpathways is Cell adhesion molecules (CAMs). The drugs Doxorubicin and Atrasentan have been mentioned in the context of this disorder. Affiliated tissues include breast, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Peritoneal Serous Papillary Adenocarcinoma

Graphical network of the top 20 diseases related to Peritoneal Serous Papillary Adenocarcinoma:



Diseases related to Peritoneal Serous Papillary Adenocarcinoma

Symptoms & Phenotypes for Peritoneal Serous Papillary Adenocarcinoma

MGI Mouse Phenotypes related to Peritoneal Serous Papillary Adenocarcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.55 CLDN4 PIP PTGER4 SFTPC WT1
2 hematopoietic system MP:0005397 9.35 CLDN4 HLA-DQA1 PIP PTGER4 WT1
3 immune system MP:0005387 9.02 HLA-DQA1 PIP PTGER4 SFTPC WT1

Drugs & Therapeutics for Peritoneal Serous Papillary Adenocarcinoma

Drugs for Peritoneal Serous Papillary Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
2
Atrasentan Investigational Phase 2 173937-91-2, 195733-43-8 159594
3 Anti-Bacterial Agents Phase 2
4 Antibiotics, Antitubercular Phase 2
5 Endothelin A Receptor Antagonists Phase 2
6 Endothelin Receptor Antagonists Phase 2
7 taxane Phase 2
8 Topoisomerase Inhibitors Phase 2
9
Liposomal doxorubicin Phase 2 31703

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase II Study of Atrasentan (ABT-627) Plus DOXIL in Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Serous Papillary Adenocarcinoma Following Platinum + Taxane Therapy Terminated NCT00653328 Phase 2 atrasentan hydrochloride;doxil

Search NIH Clinical Center for Peritoneal Serous Papillary Adenocarcinoma

Genetic Tests for Peritoneal Serous Papillary Adenocarcinoma

Anatomical Context for Peritoneal Serous Papillary Adenocarcinoma

MalaCards organs/tissues related to Peritoneal Serous Papillary Adenocarcinoma:

40
Breast

Publications for Peritoneal Serous Papillary Adenocarcinoma

Articles related to Peritoneal Serous Papillary Adenocarcinoma:

# Title Authors PMID Year
1
[A case of peritoneal serous papillary carcinoma]. 61
21829076 2011
2
[A case of peritoneal serous papillary adenocarcinoma]. 61
19295280 2009
3
Serous papillary adenocarcinoma of the female genital organs and invasive micropapillary carcinoma of the breast. Are WT1, CA125, and GCDFP-15 useful in differential diagnosis? 61
18339419 2008
4
Claudin 4 identifies a wide spectrum of epithelial neoplasms and represents a very useful marker for carcinoma versus mesothelioma diagnosis in pleural and peritoneal biopsies and effusions. 61
17609977 2007
5
Peritoneal serous papillary adenocarcinoma: report of four cases. 61
16258208 2005
6
Repetitive phosphorus-32 peritoneal instillations in a patient with malignant ascites. 61
12819405 2003
7
Two cases of peritoneal serous papillary adenocarcinoma. 61
1721482 1991

Variations for Peritoneal Serous Papillary Adenocarcinoma

Expression for Peritoneal Serous Papillary Adenocarcinoma

Search GEO for disease gene expression data for Peritoneal Serous Papillary Adenocarcinoma.

Pathways for Peritoneal Serous Papillary Adenocarcinoma

Pathways related to Peritoneal Serous Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.79 HLA-DQA1 CLDN4

GO Terms for Peritoneal Serous Papillary Adenocarcinoma

Sources for Peritoneal Serous Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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