MCID: PRT036
MIFTS: 66

Peritonitis

Categories: Endocrine diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Peritonitis

MalaCards integrated aliases for Peritonitis:

Name: Peritonitis 12 76 55 6 44 15 73
Retractile Mesenteritis 12 53 73
Sclerosing Mesenteritis 12 53 73
Peritoneal Retractile Mesenteritis 53 73
Acute Generalized Peritonitis 12 73
Primary Bacterial Peritonitis 12 73
Mesenteric Panniculitis 53 73
Idiopathic Sclerosing Mesenteritis 53
Liposclerotic Mesenteritis 53
Mesenteric Lipodystrophy 53
Mesenteric Lipogranuloma 53
Mesenteric Fibromatosis 53
Fibromatosis, Abdominal 73

Classifications:



Summaries for Peritonitis

NIH Rare Diseases : 53 Sclerosing mesenteritis is one of many terms that describes a spectrum of inflammatory disorders that affect the mesentery. The mesentery is the membrane that anchors the small intestine to the back of the abdominal wall. The condition mostly affects men between their 40s and 60s, but women and children can also be affected. It may result in a variety of symptoms including abdominal pain, nausea and vomiting, constipation or diarrhea, weight loss, and fever. Some people have an abdominal mass. The cause of the condition is poorly understood. Suggested possible causes have included previous abdominal surgery or trauma, autoimmunity, paraneoplastic syndromes, ischemic injury, and infection. Treatment depends on the symptoms in each person and may include the use of glucocorticoids, hormonal therapy (tamoxifen or progesterone), or other medications, either alone or in combination (i.e. glucocorticoids in combination with tamoxifen). Surgery may be needed for an obstruction, if present. Although there are case reports of patients with aggressive disease and fatalities, it appears that the condition usually remains stable or is slowly progessive. In some cases, the condition goes away on its own.

MalaCards based summary : Peritonitis, also known as retractile mesenteritis, is related to primary peritoneal carcinoma and tuberculous peritonitis. An important gene associated with Peritonitis is TMEM67 (Transmembrane Protein 67), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Ertapenem and Mupirocin have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and neutrophil, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : 12 A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.

Wikipedia : 76 Peritonitis is inflammation of the peritoneum, the lining of the inner wall of the abdomen and cover of... more...

Related Diseases for Peritonitis

Diseases related to Peritonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1215)
# Related Disease Score Top Affiliating Genes
1 primary peritoneal carcinoma 34.1 CXCL8 IL10 MUC16
2 tuberculous peritonitis 33.7 ADA ALB CRP MUC16 TNF
3 familial mediterranean fever 33.1 CRP IL1B MEFV TNF
4 appendicitis 32.5 ALB CRP CXCL8 IL10 IL1B IL6
5 systemic onset juvenile idiopathic arthritis 31.7 MEFV TNF
6 endometriosis 31.2 CCL2 CXCL8 IL1B IL6
7 end stage renal failure 31.0 ALB CRP IL6 TNF
8 kidney disease 30.4 ALB B2M CCL2 CRP IL6 TMEM67
9 uremia 30.4 ALB B2M CRP
10 echinococcosis 30.4 IL10 IL6 TLR2 TNF
11 fasciitis 30.4 CXCL8 IL6 TNF
12 acute pancreatitis 30.4 CRP CXCL8 IL10 IL6
13 endometritis 30.3 IL1B IL6 TNF
14 alcoholic liver cirrhosis 30.3 ALB CXCL8 F2
15 colitis 30.2 CXCL8 IL10 IL1B IL6 TNF
16 spondylitis 30.2 CRP IL6 TNF
17 peptic ulcer disease 30.2 CXCL8 IL10 IL1B TNF
18 liver disease 30.2 ALB F2 IL6 TNF
19 analbuminemia 30.2 ALB CRP F2
20 streptococcal toxic-shock syndrome 30.2 CXCL8 IL6 TNF
21 neutrophil migration 30.1 CXCL8 ICAM1 ITGAM
22 chronic kidney failure 30.1 ALB B2M CRP ICAM1 IL6
23 atrophic gastritis 30.1 CXCL8 IL1B TNF
24 spondyloarthropathy 1 30.1 B2M CRP TNF
25 perinatal necrotizing enterocolitis 30.1 CRP CXCL8 IL1B IL6 TNF
26 fascioliasis 30.1 ALB IL10 IL1B
27 uremic pruritus 30.1 CRP IL1B IL6
28 mycobacterium chelonae 30.1 CXCL8 TLR2
29 mycobacterium abscessus 30.1 CXCL8 TLR2 TNF
30 hepatic encephalopathy 30.0 ALB F2 IL6 TNF
31 temporal arteritis 30.0 CCL2 CRP IL6 TNF
32 viral infectious disease 30.0 CXCL8 IL10 IL1B IL6 TNF
33 protein-energy malnutrition 30.0 ALB IL6 TNF
34 thrombocytosis 30.0 CRP F2 IL6
35 abdominal tuberculosis 30.0 ADA ALB CRP F2
36 arthritis 29.9 CCL2 CXCL8 IL10 IL1B IL6 TNF
37 miliary tuberculosis 29.9 ADA MUC16 TNF
38 takayasu arteritis 29.9 CRP IL6 TNF
39 autoimmune disease 29.9 CCL2 IL10 IL1B IL6 TNF
40 pelvic inflammatory disease 29.9 CCL2 CRP TLR2
41 purpura 29.9 CRP F2 IL6 TNF
42 cystitis 29.8 CCL2 CRP CXCL8 IL6 TNF
43 hydronephrosis 29.8 ALB B2M CCL2
44 spondyloarthropathy 29.8 IL10 IL6 TNF
45 glomerulonephritis 29.8 ALB CCL2 ICAM1 IL1B
46 peripheral vascular disease 29.8 ALB CRP F2 IL6
47 haemophilus influenzae 29.8 CXCL8 IL1B TLR2 TNF
48 melioidosis 29.8 IL10 IL6 TLR2 TNF
49 compartment syndrome 29.8 ALB F2 TNF
50 osteomyelitis 29.8 CXCL8 IL10 IL1B IL6 TNF

Comorbidity relations with Peritonitis via Phenotypic Disease Network (PDN): (show all 13)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Chronic Kidney Failure Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Intestinal Obstruction Intestinal Perforation
Paralytic Ileus Protein-Energy Malnutrition
Respiratory Failure

Graphical network of the top 20 diseases related to Peritonitis:



Diseases related to Peritonitis

Symptoms & Phenotypes for Peritonitis

GenomeRNAi Phenotypes related to Peritonitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.77 AQP1 CXCL8 F2 ICAM1 IL10 IL1B
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.77 AQP1 CXCL8 F2 ICAM1 IL10 IL1B

MGI Mouse Phenotypes related to Peritonitis:

46 (show all 14)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.35 ADA AQP1 B2M CRP CXCL2 F2
2 homeostasis/metabolism MP:0005376 10.31 ADA ALB AQP1 B2M CRP F2
3 hematopoietic system MP:0005397 10.27 ADA AQP1 B2M F2 ICAM1 IL10
4 cellular MP:0005384 10.26 ADA ALB B2M ICAM1 IL10 IL6
5 growth/size/body region MP:0005378 10.26 ADA AQP1 B2M F2 ICAM1 IL10
6 immune system MP:0005387 10.25 ADA B2M CCL2 CRP F2 ICAM1
7 digestive/alimentary MP:0005381 10.21 ADA ALB B2M F2 ICAM1 IL10
8 endocrine/exocrine gland MP:0005379 10.15 ADA ALB AQP1 B2M ICAM1 IL10
9 mortality/aging MP:0010768 10.07 ADA ALB AQP1 B2M F2 ICAM1
10 integument MP:0010771 10.02 B2M F2 ICAM1 IL10 IL1B IL6
11 liver/biliary system MP:0005370 10.02 ADA ALB B2M IL10 IL6 LBP
12 neoplasm MP:0002006 9.76 ALB B2M ICAM1 IL10 IL1B IL6
13 nervous system MP:0003631 9.7 AQP1 B2M F2 ICAM1 IL10 IL1B
14 skeleton MP:0005390 9.32 ADA AQP1 F2 IL10 IL1B IL6

Drugs & Therapeutics for Peritonitis

Drugs for Peritonitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 311)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ertapenem Approved, Investigational Phase 4,Phase 2 153832-46-3 150610
2
Mupirocin Approved, Investigational, Vet_approved Phase 4,Not Applicable 12650-69-0 446596
3
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 2713 9552079
4
Spironolactone Approved Phase 4,Not Applicable 52-01-7, 1952-01-7 5833
5
Losartan Approved Phase 4 114798-26-4 3961
6
Hydralazine Approved Phase 4 86-54-4 3637
7
Enalapril Approved, Vet_approved Phase 4 75847-73-3 5362032 40466924
8
Enalaprilat Approved Phase 4 76420-72-9 6917719
9
Benzocaine Approved, Investigational Phase 4,Not Applicable 94-09-7, 1994-09-7 2337
10
Angiotensin II Approved, Investigational Phase 4 11128-99-7, 68521-88-0, 4474-91-3 172198 65143
11 tannic acid Approved Phase 4,Not Applicable
12
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
13
Cefotaxime Approved Phase 4,Phase 3,Not Applicable 63527-52-6 456256 5742673
14
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 85721-33-1 2764
15
Azithromycin Approved Phase 4 83905-01-5 55185 447043
16
Vancomycin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1404-90-6 14969 441141
17
Cefoxitin Approved Phase 4,Phase 3,Not Applicable 35607-66-0 441199
18
Imipenem Approved Phase 4,Phase 3,Not Applicable 74431-23-5, 64221-86-9 104838
19
Carvedilol Approved, Investigational Phase 4,Not Applicable 72956-09-3 2585
20
Propranolol Approved, Investigational Phase 4,Phase 3,Not Applicable 525-66-6 4946
21
Ceftazidime Approved Phase 4,Phase 2,Phase 3,Not Applicable 78439-06-2, 72558-82-8 5481173
22
Cefazolin Approved Phase 4,Phase 3,Not Applicable 25953-19-9 656510 33255
23
Norfloxacin Approved Phase 4,Phase 2,Phase 3,Not Applicable 70458-96-7 4539
24
Cefepime Approved, Investigational Phase 4,Not Applicable 88040-23-7 5479537
25
Icodextrin Approved, Investigational Phase 4,Phase 2,Phase 1 337376-15-5
26
Caspofungin Approved Phase 4 179463-17-3, 162808-62-0 468682 2826718
27
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
28
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
29
Ceftriaxone Approved Phase 4,Phase 3,Not Applicable 73384-59-5 5479530 5361919
30
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 10909430 439542
31
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
32
Minocycline Approved, Investigational Phase 4,Phase 3 10118-90-8 5281021
33
Tigecycline Approved Phase 4,Phase 3 220620-09-7 5282044
34
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
35
Sultamicillin Approved, Investigational Phase 4 76497-13-7
36
Sulbactam Approved Phase 4 68373-14-8
37
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
38
Cilastatin Approved, Investigational Phase 4,Phase 3 82009-34-5 6435415 5280454
39
Warfarin Approved Phase 4,Not Applicable 81-81-2 6691 54678486
40
Heparin Approved, Investigational Phase 4,Phase 2,Not Applicable 9005-49-6 772 46507594
41
Dipyridamole Approved Phase 4 58-32-2 3108
42
Dalteparin Approved Phase 4,Not Applicable 9005-49-6
43
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
44
Nadroparin Approved, Investigational Phase 4
45
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3 135968-09-1
46
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 616-91-1 12035
47
Lactulose Approved Phase 4,Not Applicable 4618-18-2 11333
48
chenodeoxycholic acid Approved Phase 4,Phase 3 474-25-9 10133
49
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
50
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251

Interventional clinical trials:

(show top 50) (show all 333)
# Name Status NCT ID Phase Drugs
1 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Unknown status NCT00761098 Phase 4 Standard Care;Experimental
2 Probiotics Use in the Chronic Peritoneal Dialysis Patients Unknown status NCT01076426 Phase 4 Pro-biotics
3 PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM) Unknown status NCT02277262 Phase 4
4 Antibiotics Versus Surgery in Acute Appendicitis Unknown status NCT01421901 Phase 4 Ertapenem
5 Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis Unknown status NCT00751374 Phase 4 gentamicin;gentamicin cream alternating with mupirocin cream
6 FEcal Transplant, a Hope to Eradicate Colonization of Patient Harboring eXtreme Drug Resistant Bacteria? Unknown status NCT03029078 Phase 4 fecal microbiota transplant
7 Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection Unknown status NCT02547103 Phase 4
8 The Effect of Enalapril and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients Unknown status NCT01041963 Phase 4 Enalapril;Enalapril plus Losartan;Placebo
9 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Unknown status NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
10 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis Unknown status NCT01820026 Phase 4 Imipenem;Vancomycin;azithromycin;Cefotaxime;Amoxicillin
11 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
12 The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding Unknown status NCT02695732 Phase 4 Carvedilol
13 The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding Unknown status NCT02385422 Phase 4 Carvedilol;Propranolol
14 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites Unknown status NCT02755701 Phase 4 Branched-chain Amino Acid;Placebo
15 Prospective Comparison of Primary Abdominal Closure and Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
16 Comparing Cefepime Versus Cefazolin Plus Ceftazidime for CAPD-associated Peritonitis Completed NCT02872038 Phase 4 Cefepime;Cefazolin plus Ceftazidime
17 Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis Completed NCT01817309 Phase 4
18 Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis Completed NCT01044446 Phase 4 Icodextrin;glucose-based peritoneal dialysate
19 IV Antibiotics With Lavage for Severe PD Peritonitis Completed NCT02926846 Phase 4 Intravenous vancomycin & gentamicin with adjunctive lavage;Intraperitoneal vancomycin & gentamicin
20 Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis Completed NCT02805049 Phase 4 Echinocandins
21 Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention Completed NCT01542801 Phase 4 Norfloxacin;ciprofloxacin
22 Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis Completed NCT00359853 Phase 4 Oral norfloxacin
23 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
24 Comparison of Efficacy of Cefotaxime, Ceftriaxone, and Ciprofloxacin for the Treatment of SBP in Patients With LC Completed NCT01265173 Phase 4 Cefotaxime;Ceftriaxone;Ciprofloxacin
25 Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD. Completed NCT00255619 Phase 4
26 Beneficial Effect of Probiotics on Chronic Kidney Disease Completed NCT01391468 Phase 4
27 Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery Completed NCT00488904 Phase 4
28 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
29 Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children Completed NCT01632046 Phase 4 lactate and bicarbonate buffered dialysis solutions
30 Use of Ointments in Prevention of Catheter Related Infections in PD Completed NCT00400595 Phase 4 Mupirocin ointment;Polysporin Triple
31 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
32 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial Completed NCT01760967 Phase 4 Dexmedetomidine
33 COMPRES - COMpression Anastomosis Ring (CAR™ 27/ColonRing™) Post maRketing Evaluation Study Completed NCT01091155 Phase 4
34 T.E.A. Study Three Days Ertapenem Versus Three Days Ampicillin- Sulbactam Completed NCT00630513 Phase 4 Ertapenem;Ampicillin-Sulbactam
35 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
36 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
37 A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection Completed NCT01721408 Phase 4 Tigecycline;Imipenem/cilastatin
38 Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques Completed NCT01463540 Phase 4
39 Effect of Glucose Degradation Products (GDP) on Endothelial Dysfunction Completed NCT01315314 Phase 4 Balance, Fresenius Medical Care, Germany
40 Non Operative Treatment for Acute Appendicitis Completed NCT01096927 Phase 4 Amoxicillin and Clavulanic Acid
41 The Effect of Neutral Peritoneal Dialysis (PD) Solution With Minimal Glucose-Degradation-Product (GDP) on Fluid Status and Body Composition Completed NCT00966615 Phase 4
42 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection Completed NCT02247414 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
43 Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Peritonitis Recruiting NCT03771170 Phase 4 Rheosorbilact®;Ringer lactate
44 The Efficacy of Prolonged Antibiotic Therapy for the Prevention of Relapsing Peritonitis in Peritoneal Dialysis Patients With High Dialysis Effluent Bacterial DNA Fragment Levels Recruiting NCT02593201 Phase 4 Extended antibiotics (cefazolin or ceftazidime);Usual antibiotics (cefazolin or ceftazidime)
45 GCSF in Alcoholic Hepatitis Recruiting NCT03703674 Phase 4 GCSF
46 Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis Recruiting NCT02308111 Phase 4 Obeticholic Acid (OCA);Placebo
47 G-CSF Plus NAC In Severe Alcoholic Hepatitis Recruiting NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
48 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy Recruiting NCT02238444 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
49 Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation Recruiting NCT03148002 Phase 4 Current Bowel Protocol (senna/lactulose);PEG Bowel Protocol (PEG/lactulose)
50 Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C Recruiting NCT03633279 Phase 4 Branched chain amino acid;Placebo

Search NIH Clinical Center for Peritonitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: peritonitis

Genetic Tests for Peritonitis

Anatomical Context for Peritonitis

MalaCards organs/tissues related to Peritonitis:

41
Liver, Colon, Neutrophil, Small Intestine, Kidney, Testes, Lung

Publications for Peritonitis

Articles related to Peritonitis:

(show top 50) (show all 2601)
# Title Authors Year
1
Advanced prostate cancer discovered with cancerous peritonitis: Case report. ( 30510901 )
2019
2
The Prevention of Carboxymethylcellulose on Bowel Adhesions Induced by Talc Peritonitis in Mice. ( 30527490 )
2019
3
A RETROSPECTIVE ANALYSIS OF ETIOLOGY AND OUTCOMES OF REFRACTORY CAPD PERITONITIS IN A TERTIARY CARE CENTER FROM NORTH INDIA. ( 29386307 )
2018
4
Photobiomodulation reduces neutrophil migration and oxidative stress in mice with carrageenan-induced peritonitis. ( 29951878 )
2018
5
Peritoneal dialysis-related peritonitis: challenges and solutions. ( 29928142 )
2018
6
Meta-analysis of surgical strategies in perforated left colonic diverticulitis with generalized peritonitis. ( 29931505 )
2018
7
Tracking Competent Host Defence to Chronic Inflammation: An In Vivo Model of Peritonitis. ( 29322409 )
2018
8
Secondary peritonitis: principles of diagnosis and intervention. ( 29914871 )
2018
9
Immunosuppression Induced by Perioperative Peritonitis Promotes Lung Metastasis. ( 29970570 )
2018
10
OUTCOMES OF<i>ACINETOBACTER</i>PERITONITIS IN PERITONEAL DIALYSIS PATIENTS: A MULTICENTER REGISTRY ANALYSIS. ( 29437143 )
2018
11
Authors reply: Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis-the risk of overtreatment. ( 29980887 )
2018
12
Polymicrobial Anaerobic Bacteremia Caused by Butyricimonas virosa and Brachyspira pilosicoli in a Patient with Peritonitis following Intestinal Perforation. ( 29071824 )
2018
13
Unusual Cause of Peritonitis in Peritoneal Dialysis: Streptococcus vestibularis. ( 29377513 )
2018
14
Pooled analysis of 163 published tuberculous peritonitis cases from Turkey ( 29714445 )
2018
15
A rare case of peritonitis due to <i>Brevundimonas vesicularis</i>. ( 29915660 )
2018
16
Fecal peritonitis in aging rat model. Therapeutic response to different antibiotic strategies. ( 29924208 )
2018
17
Tuberculous peritonitis and pleurisy accompanied by pulmonary cryptococcosis: A case report. ( 29756504 )
2018
18
Barium peritonitis with abdominal abscessation. ( 29923195 )
2018
19
Sclerosing encapsulating peritonitis after living-donor liver transplantation: A case series, Kyoto experience. ( 29896575 )
2018
20
A Rare Colonization in the Peritonitis Following Blunt Abdominal Trauma. ( 29449198 )
2018
21
Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis: the risk of overtreatment. ( 29948522 )
2018
22
Microbiology and antibiotic susceptibility patterns in spontaneous bacterial peritonitis: A study of two Dutch cohorts at a 10-year interval. ( 29881617 )
2018
23
Clinical and microbiological characteristics of peritoneal dialysis-related peritonitis caused by Escherichia coli in southern Taiwan. ( 29931659 )
2018
24
Severe persistent hypocholesterolemia after emergency gastrointestinal surgery predicts in-hospital mortality in critically ill patients with diffuse peritonitis. ( 29979773 )
2018
25
Homocysteine: a new diagnostic marker for spontaneous bacterial peritonitis? ( 29979324 )
2018
26
Should We Use Adenosine Deaminase Assay for the Differential Diagnosis of Tuberculous Peritonitis in CAPD Patients? ( 29563278 )
2018
27
A case of twin IVF pregnancy complicated with sclerosing encapsulating peritonitis diagnosed at caesarean delivery. ( 29430973 )
2018
28
COMPREHENSIVE APPROACH TO PERITONEAL DIALYSIS-RELATED PERITONITIS BY ENTERIC MICROORGANISMS. COMPARISON BETWEEN SINGLE ORGANISM AND POLYMICROBIAL INFECTIONS. ( 29386310 )
2018
29
Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis. ( 28799242 )
2018
30
Diagnostic validity of flow cytometry vs manual counting of polymorphonuclear leukocytes in spontaneous bacterial peritonitis. ( 29383775 )
2018
31
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. ( 29558895 )
2018
32
A retrospective study of the neuropathology and diagnosis of naturally occurring feline infectious peritonitis. ( 29411701 )
2018
33
Intestinal perforation by a peritoneal dialysis catheter in which fungal peritonitis led to diagnosis: a rare case report. ( 29611117 )
2018
34
Delayed, diffuse acute peritonitis secondary to misplacement of a cystogastrostomic &amp;quot;pigtail&amp;quot; drain in an outpatient after discharge. ( 29957760 )
2018
35
Complete abdominal wound and anastomotic leak with diffuse peritonitis closure achieved by an abdominal vacuum sealing drainage in a critical ill patient: a case report. ( 29907107 )
2018
36
Mesenteric fibromatosis: a rare cause of peritonitis. ( 29424348 )
2018
37
Effects of acute ethanol intoxication in an ovine peritonitis model. ( 29921225 )
2018
38
<i>Gemella haemolysans</i> bacteremia in a patient with secondary peritonitis due to a duodenal ulcer perforation: A case report. ( 29942771 )
2018
39
Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( 29946179 )
2018
40
Letter: the efficacy and safety of rifaximin for the prophylaxis of spontaneous bacterial peritonitis in cirrhotic patients. ( 29417632 )
2018
41
Spontaneous bacterial peritonitis due to Helicobacter pylori in a cirrhotic patient with human immunodeficiency virus and hepatitis C virus coinfection. ( 29429754 )
2018
42
Eucalyptus globulus Inhibits Inflammasome-Activated Pro-Inflammatory Responses and Ameliorate Monosodium Urate-Induced Peritonitis in Murine Experimental Model. ( 29433388 )
2018
43
Comparison of the performance of laboratory tests in the diagnosis of feline infectious peritonitis. ( 29429403 )
2018
44
Postoperative granulomatous peritonitis mimicking abdominal tuberculosis. ( 30214769 )
2018
45
The Influence of Carbon Dioxide Pneumoperitoneum on Systemic Inflammatory Response Syndrome and Bacterial Translocation in Patients With Bacterial Peritonitis Caused by Acute Appendicitis. ( 29099329 )
2018
46
Candida glabrata PD-Associated Peritonitis: A Case Report. ( 30185486 )
2018
47
Listeria peritonitis and bacteremia in a patient with cholangiocarcinoma. ( 30416965 )
2018
48
Severe peritonitis after successful endoscopic ultrasound-guided gallbladder drainage for acute gangrenous cholecystitis. ( 29631302 )
2018
49
Correction: Severe peritonitis after successful endoscopic ultrasound-guided gallbladder drainage for acute gangrenous cholecystitis. ( 30125916 )
2018
50
Acute Diffuse Peritonitis Caused by Urinary Retention: A Rare Case of Gangrenous Cystitis. ( 29984034 )
2018

Variations for Peritonitis

ClinVar genetic disease variations for Peritonitis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 TMEM67 NM_153704.5(TMEM67): c.1843T> C (p.Cys615Arg) single nucleotide variant Pathogenic/Likely pathogenic rs201893408 GRCh37 Chromosome 8, 94808198: 94808198
2 TMEM67 NM_153704.5(TMEM67): c.1843T> C (p.Cys615Arg) single nucleotide variant Pathogenic/Likely pathogenic rs201893408 GRCh38 Chromosome 8, 93795970: 93795970
3 TMEM67 NM_153704.5(TMEM67): c.1321C> T (p.Arg441Cys) single nucleotide variant Pathogenic/Likely pathogenic rs752362727 GRCh38 Chromosome 8, 93786255: 93786255
4 TMEM67 NM_153704.5(TMEM67): c.1321C> T (p.Arg441Cys) single nucleotide variant Pathogenic/Likely pathogenic rs752362727 GRCh37 Chromosome 8, 94798483: 94798483

Expression for Peritonitis

Search GEO for disease gene expression data for Peritonitis.

Pathways for Peritonitis

Pathways related to Peritonitis according to GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.12 B2M CCL2 CRP CXCL2 CXCL8 ICAM1
2
Show member pathways
13.61 CCL2 CXCL8 F2 ICAM1 IL10 IL1B
3
Show member pathways
13.5 CCL2 CXCL2 CXCL8 IL10 IL1B IL6
4
Show member pathways
13.47 B2M CCL2 CXCL2 CXCL8 ICAM1 IL10
5
Show member pathways
13.35 CCL2 CXCL2 CXCL8 IL10 IL1B IL6
6
Show member pathways
13.17 B2M CCL2 CXCL2 CXCL8 ICAM1 IL1B
7
Show member pathways
13.09 CCL2 CXCL2 CXCL8 IL10 IL1B IL6
8
Show member pathways
12.98 B2M CXCL8 ICAM1 IL10 IL1B IL6
9
Show member pathways
12.91 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
10
Show member pathways
12.69 CCL2 F2 IL10 IL1B IL6 TNF
11 12.67 B2M CCL2 IL10 IL1B TLR2 TNF
12
Show member pathways
12.66 IL10 IL1B IL6 TLR2 TNF
13
Show member pathways
12.47 CCL2 CXCL2 CXCL8 IL1B IL6 TLR2
14
Show member pathways
12.45 IL10 IL1B IL6 TNF
15
Show member pathways
12.4 CXCL8 IL1B IL6 LBP TNF
16 12.4 B2M ICAM1 IL6 TLR2 TNF
17
Show member pathways
12.37 IL10 IL1B ITGAM TLR2 TNF
18
Show member pathways
12.37 ALB CCL2 CRP F2 ICAM1 IL1B
19
Show member pathways
12.36 CCL2 CXCL2 CXCL8 F2 ICAM1 IL1B
20
Show member pathways
12.34 CXCL8 IL1B IL6 LBP TLR2 TNF
21 12.34 IL10 IL1B IL6 ITGAM LBP TLR2
22
Show member pathways
12.33 CXCL8 IL10 IL1B IL6 TNF
23
Show member pathways
12.33 CXCL8 IL1B IL6 TLR2 TNF
24
Show member pathways
12.31 CXCL8 IL6 TLR2 TNF
25 12.29 CXCL8 IL10 IL1B IL6 TNF
26
Show member pathways
12.27 IL10 IL1B IL6 TNF
27
Show member pathways
12.19 F2 IL1B IL6 ITGAM TLR2 TNF
28
Show member pathways
12.18 CCL2 CXCL8 ICAM1 IL10 IL1B IL6
29
Show member pathways
12.18 IL10 IL1B IL6 TLR2 TNF
30 12.17 CCL2 ICAM1 IL1B TNF
31 12.12 CCL2 CXCL2 ICAM1 IL1B IL6 TNF
32 12.08 IL10 IL6 ITGAM TNF
33 12.06 CCL2 CXCL8 ICAM1 IL1B IL6 TNF
34 12.03 CXCL2 CXCL8 ICAM1 IL1B LBP TNF
35 12 IL1B IL6 ITGAM TNF
36 12 AQP1 CCL2 CXCL2 CXCL8 ICAM1 IL1B
37 11.99 CXCL2 CXCL8 IL1B IL6 LBP
38
Show member pathways
11.97 CXCL8 ICAM1 IL6 LBP
39 11.93 CXCL8 IL10 IL1B IL6 ITGAM TLR2
40 11.91 IL10 IL1B ITGAM TNF
41 11.91 IL10 IL1B IL6 ITGAM TNF
42 11.89 CCL2 IL10 IL1B IL6 TNF
43 11.87 CXCL8 IL10 IL1B IL6 ITGAM TNF
44 11.87 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
45 11.87 CCL2 CXCL8 ICAM1 IL10 IL1B IL6
46
Show member pathways
11.85 CRP IL6 LBP
47 11.83 CXCL8 ICAM1 IL6
48 11.75 CCL2 CXCL2 CXCL8 IL1B IL6 TNF
49
Show member pathways
11.73 CXCL2 CXCL8 ICAM1 IL1B IL6 TNF
50 11.68 CCL2 IL1B ITGAM TLR2 TNF

GO Terms for Peritonitis

Cellular components related to Peritonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.97 ALB AQP1 B2M F2 ICAM1 IL1B
2 cell surface GO:0009986 9.8 ADA B2M ICAM1 ITGAM LBP TLR2
3 extracellular region GO:0005576 9.77 ALB B2M CCL2 CRP CXCL2 CXCL8
4 membrane raft GO:0045121 9.67 ICAM1 ITGAM TLR2 TNF
5 external side of plasma membrane GO:0009897 9.63 ADA B2M F2 ICAM1 ITGAM TNF
6 extracellular space GO:0005615 9.53 ADA ALB B2M CCL2 CRP CXCL2

Biological processes related to Peritonitis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.99 ICAM1 IL1B ITGAM TNF
2 response to hypoxia GO:0001666 9.97 ADA ICAM1 IL1B TLR2
3 response to lipopolysaccharide GO:0032496 9.97 ICAM1 IL10 IL1B LBP TLR2
4 immune response GO:0006955 9.97 B2M CCL2 CXCL2 CXCL8 IL10 IL1B
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.95 ICAM1 IL1B IL6 TLR2 TNF
6 positive regulation of DNA-binding transcription factor activity GO:0051091 9.94 IL10 IL1B IL6 TNF
7 neutrophil chemotaxis GO:0030593 9.92 CCL2 CXCL2 CXCL8 IL1B
8 cellular response to interleukin-1 GO:0071347 9.9 CCL2 CXCL8 ICAM1
9 chemokine-mediated signaling pathway GO:0070098 9.89 CCL2 CXCL2 CXCL8
10 response to insulin GO:0032868 9.89 ICAM1 IL10 TLR2
11 response to glucocorticoid GO:0051384 9.89 IL10 IL1B IL6 TNF
12 defense response to Gram-positive bacterium GO:0050830 9.89 CRP IL6 LBP TLR2 TNF
13 cellular response to organic cyclic compound GO:0071407 9.88 CCL2 IL1B TNF
14 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.88 CXCL2 CXCL8 F2
15 humoral immune response GO:0006959 9.86 CCL2 IL6 TNF
16 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.85 IL1B TLR2 TNF
17 inflammatory response GO:0006954 9.85 CCL2 CRP CXCL2 CXCL8 IL10 IL1B
18 positive regulation of nitric oxide biosynthetic process GO:0045429 9.84 ICAM1 IL1B TNF
19 protein kinase B signaling GO:0043491 9.83 CCL2 IL1B TNF
20 acute-phase response GO:0006953 9.83 CRP F2 IL6 LBP
21 positive regulation of interleukin-6 production GO:0032755 9.83 IL1B IL6 LBP TLR2 TNF
22 negative regulation of neurogenesis GO:0050768 9.81 IL1B IL6 TNF
23 leukocyte chemotaxis GO:0030595 9.8 CXCL2 CXCL8 IL10
24 positive regulation of neutrophil chemotaxis GO:0090023 9.8 CXCL8 IL1B LBP
25 microglial cell activation GO:0001774 9.79 ITGAM TLR2 TNF
26 embryonic digestive tract development GO:0048566 9.78 ADA CXCL8 TNF
27 positive regulation of interleukin-8 production GO:0032757 9.78 IL1B LBP TLR2 TNF
28 positive regulation of glial cell proliferation GO:0060252 9.77 IL1B IL6 TNF
29 lipopolysaccharide-mediated signaling pathway GO:0031663 9.77 CCL2 IL1B LBP TLR2 TNF
30 negative regulation of growth of symbiont in host GO:0044130 9.76 IL10 LBP TNF
31 positive regulation of chemokine production GO:0032722 9.76 IL6