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MCID: PRT036
MIFTS: 66

Peritonitis

Categories: Rare diseases, Gastrointestinal diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Peritonitis

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MalaCards integrated aliases for Peritonitis:

Name: Peritonitis 12 76 55 6 15 73
Retractile Mesenteritis 12 53 73
Sclerosing Mesenteritis 12 53 73
Peritoneal Retractile Mesenteritis 53 73
Acute Generalized Peritonitis 12 73
Primary Bacterial Peritonitis 12 73
Mesenteric Panniculitis 53 73
Idiopathic Sclerosing Mesenteritis 53
Liposclerotic Mesenteritis 53
Mesenteric Lipodystrophy 53
Mesenteric Lipogranuloma 53
Mesenteric Fibromatosis 53
Fibromatosis, Abdominal 73

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)
ICD10: 33


Sources

Summaries for Peritonitis

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NIH Rare Diseases : 53 Sclerosing mesenteritis is one of many terms that describes a spectrum of inflammatory disorders that affect the mesentery. The mesentery is the membrane that anchors the small intestine to the back of the abdominal wall. The condition mostly affects men between their 40s and 60s, but women and children can also be affected. It may result in a variety of symptoms including abdominal pain, nausea and vomiting, constipation or diarrhea, weight loss, and fever. Some people have an abdominal mass. The cause of the condition is poorly understood. Suggested possible causes have included previous abdominal surgery or trauma, autoimmunity, paraneoplastic syndromes, ischemic injury, and infection. Treatment depends on the symptoms in each person and may include the use of glucocorticoids, hormonal therapy (tamoxifen or progesterone), or other medications, either alone or in combination (i.e. glucocorticoids in combination with tamoxifen). Surgery may be needed for an obstruction, if present. Although there are case reports of patients with aggressive disease and fatalities, it appears that the condition usually remains stable or is slowly progessive. In some cases, the condition goes away on its own.

MalaCards based summary : Peritonitis, also known as retractile mesenteritis, is related to primary peritoneal carcinoma and tuberculous peritonitis. An important gene associated with Peritonitis is ALB (Albumin), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Spironolactone and Ertapenem have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and kidney, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : 12 A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.

Wikipedia : 76 Peritonitis is inflammation of the peritoneum, the lining of the inner wall of the abdomen and cover of... more...

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Related Diseases for Peritonitis

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Diseases related to Peritonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 988)
# Related Disease Score Top Affiliating Genes
1 primary peritoneal carcinoma 34.6 CXCL8 IL10 MUC16
2 tuberculous peritonitis 33.7 ADA ALB CRP MUC16 TNF
3 familial mediterranean fever 33.1 CRP IL1B MEFV TNF
4 systemic onset juvenile idiopathic arthritis 32.0 IL1B MEFV TNF
5 endometriosis 31.6 CCL2 CXCL8 IL6
6 end stage renal failure 31.2 ALB CRP IL6 TNF
7 endometritis 31.0 IL1B IL6 TNF
8 appendicitis 30.9 ALB CRP CXCL8 IL10 IL1B IL6
9 vaginitis 30.8 CXCL8 IL1B IL6
10 streptococcal toxic-shock syndrome 30.8 CXCL8 IL6 TNF
11 fasciitis 30.8 CXCL8 IL6 TNF
12 protein-energy malnutrition 30.7 ALB IL6 TNF
13 uremia 30.7 ALB B2M CRP
14 echinococcosis 30.7 IL10 IL6 TNF
15 uremic pruritus 30.7 CRP IL1B IL6
16 fascioliasis 30.7 ALB IL10 IL1B
17 mycobacterium chelonae 30.6 CXCL8 TLR2
18 hydronephrosis 30.4 ALB B2M CCL2
19 compartment syndrome 30.4 ALB F2 TNF
20 spondyloarthropathy 30.4 IL10 IL6 TNF
21 alcoholic liver cirrhosis 30.4 ALB CXCL8 F2
22 duodenal ulcer 30.3 CXCL8 IL1B TNF
23 burns 30.3 ALB IL1B TNF
24 perinatal necrotizing enterocolitis 30.3 CRP CXCL8 IL1B IL6 TNF
25 mycobacterium abscessus 30.3 CXCL8 TLR2 TNF
26 laryngitis 30.3 IL1B IL6 TNF
27 capillary leak syndrome 30.3 ALB CXCL8 IL6
28 neutrophil migration 30.3 CXCL8 ICAM1 ITGAM
29 denture stomatitis 30.2 CCL2 CXCL8 IL6
30 peripheral vascular disease 30.2 ALB CRP F2 IL6
31 monoclonal gammopathy of uncertain significance 30.2 B2M IL6 TNF
32 peptic ulcer disease 30.2 CXCL8 IL10 IL1B TNF
33 endometrial disease 30.2 CXCL8 IL1B IL6
34 meningoencephalitis 30.2 ALB B2M IL6
35 chronic kidney failure 30.2 ALB B2M CRP ICAM1 IL6
36 peripheral artery disease 30.1 CCL2 CRP IL6
37 hepatic encephalopathy 30.1 ALB F2 IL6 TNF
38 aortic aneurysm, familial abdominal, 1 30.1 CCL2 CRP IL1B IL6
39 abdominal tuberculosis 30.1 ADA ALB CRP F2
40 purpura 30.1 CRP F2 TNF
41 placenta disease 30.0 CXCL8 IL1B IL6
42 thrombocytosis 30.0 CRP F2 IL6
43 acute pancreatitis 30.0 CRP CXCL8 IL10 IL6 MPO
44 carpal tunnel syndrome 30.0 B2M IL1B IL6
45 prostatitis 30.0 CXCL8 IL10 IL1B IL6 TNF
46 pericardial effusion 30.0 ADA CRP IL6 MUC16
47 esophagitis 30.0 CXCL8 IL1B IL6
48 relapsing fever 29.9 CRP MEFV TNF
49 dengue shock syndrome 29.9 CCL2 IL1B IL6 TNF
50 cystitis 29.9 CRP CXCL8 IL6 TNF

Comorbidity relations with Peritonitis via Phenotypic Disease Network (PDN): (show all 13)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Chronic Kidney Failure Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Intestinal Obstruction Intestinal Perforation
Paralytic Ileus Protein-Energy Malnutrition
Respiratory Failure

Graphical network of the top 20 diseases related to Peritonitis:



Diseases related to Peritonitis
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Symptoms & Phenotypes for Peritonitis

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GenomeRNAi Phenotypes related to Peritonitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.83 IL1B MPO TNF AQP1 CXCL8 F2
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.83 IL10 IL1B MPO TNF AQP1 CXCL8

MGI Mouse Phenotypes related to Peritonitis:

46 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 ADA AQP1 B2M CRP F2 ICAM1
2 homeostasis/metabolism MP:0005376 10.36 IL6 ITGAM LBP MEFV MPO TLR2
3 hematopoietic system MP:0005397 10.32 TLR2 TNF ITGAM LBP MEFV MPO
4 immune system MP:0005387 10.31 ADA B2M CCL2 CRP F2 ICAM1
5 cellular MP:0005384 10.28 ITGAM MEFV TLR2 ADA ALB B2M
6 growth/size/body region MP:0005378 10.27 TMEM67 TNF ADA AQP1 B2M F2
7 digestive/alimentary MP:0005381 10.22 ADA ALB B2M F2 ICAM1 IL10
8 mortality/aging MP:0010768 10.17 ADA ALB AQP1 B2M F2 ICAM1
9 endocrine/exocrine gland MP:0005379 10.16 ADA ALB AQP1 B2M ICAM1 IL10
10 liver/biliary system MP:0005370 10.07 ADA ALB B2M IL10 IL6 LBP
11 integument MP:0010771 10.06 B2M F2 ICAM1 IL10 IL1B IL6
12 muscle MP:0005369 9.86 ADA ALB ICAM1 IL10 IL6 MPO
13 neoplasm MP:0002006 9.76 IL10 IL1B IL6 TLR2 TNF ALB
14 nervous system MP:0003631 9.7 AQP1 B2M F2 ICAM1 IL10 IL1B
15 skeleton MP:0005390 9.32 ADA AQP1 F2 IL10 IL1B IL6
Sources

Drugs & Therapeutics for Peritonitis

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Drugs for Peritonitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 295)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Spironolactone Approved Phase 4,Not Applicable 1952-01-7, 52-01-7 5833
2
Ertapenem Approved, Investigational Phase 4,Phase 2 153832-46-3 150610
3
Menthol Approved Phase 4,Phase 3,Not Applicable 2216-51-5 16666
4
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 85721-33-1 2764
5
Losartan Approved Phase 4 114798-26-4 3961
6
Enalaprilat Approved Phase 4 76420-72-9 6917719
7
Azithromycin Approved Phase 4 83905-01-5 55185 447043
8
Cefazolin Approved Phase 4,Phase 3,Not Applicable 25953-19-9 656510 33255
9
Cefoxitin Approved Phase 4,Phase 3,Not Applicable 35607-66-0 441199
10
Enalapril Approved, Vet_approved Phase 4 75847-73-3 5362032 40466924
11
Imipenem Approved Phase 4,Phase 3,Not Applicable 74431-23-5, 64221-86-9 104838
12
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
13
Propranolol Approved, Investigational Phase 4,Phase 3,Not Applicable 525-66-6 4946
14
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
15
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
16
Vancomycin Approved Phase 4,Phase 2,Phase 3,Not Applicable 1404-90-6 441141 14969
17
Cefotaxime Approved Phase 4,Phase 3,Not Applicable 63527-52-6 456256 5742673
18
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
19
Norfloxacin Approved Phase 4,Phase 2,Phase 3,Not Applicable 70458-96-7 4539
20
Ceftazidime Approved Phase 4,Phase 2,Phase 3,Not Applicable 78439-06-2, 72558-82-8 5481173
21
Carvedilol Approved, Investigational Phase 4,Not Applicable 72956-09-3 2585
22
Hydralazine Approved Phase 4 86-54-4 3637
23
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
24
Cilastatin Approved, Investigational Phase 4,Phase 3 82009-34-5 5280454 6435415
25
Ceftriaxone Approved Phase 4,Phase 3,Not Applicable 73384-59-5 5479530 5361919
26
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3 135968-09-1
27
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
28
Warfarin Approved Phase 4,Not Applicable 81-81-2 6691 54678486
29
Heparin Approved, Investigational Phase 4,Phase 2,Not Applicable 9005-49-6 772 46507594
30
Minocycline Approved, Investigational Phase 4,Phase 3 10118-90-8 5281021
31
Cefepime Approved, Investigational Phase 4,Not Applicable 88040-23-7 5479537
32
Icodextrin Approved, Investigational Phase 4,Phase 2 337376-15-5
33
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
34
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
35
Tigecycline Approved Phase 4,Phase 3 220620-09-7 5282044
36
Lactulose Approved Phase 4,Not Applicable 4618-18-2 11333
37
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 9552079 2713
38
Sulbactam Approved Phase 4 68373-14-8
39 Nadroparin Approved, Investigational Phase 4 9041-08-1
40
Dipyridamole Approved Phase 4 58-32-2 3108
41
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 616-91-1 12035
42
Dalteparin Approved Phase 4 9005-49-6
43
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
44 Sultamicillin Approved, Investigational Phase 4 76497-13-7
45
chenodeoxycholic acid Approved Phase 4,Phase 3 474-25-9 10133
46
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
47
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
48
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
49
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
50
Caspofungin Approved Phase 4 179463-17-3, 162808-62-0 468682 2826718

Interventional clinical trials:

(show top 50) (show all 301)
# Name Status NCT ID Phase Drugs
1 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Unknown status NCT00761098 Phase 4 Standard Care;Experimental
2 Probiotics Use in the Chronic Peritoneal Dialysis Patients Unknown status NCT01076426 Phase 4 Pro-biotics
3 Antibiotics Versus Surgery in Acute Appendicitis Unknown status NCT01421901 Phase 4 Ertapenem
4 Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis Unknown status NCT00751374 Phase 4 gentamicin;gentamicin cream alternating with mupirocin cream
5 The Effect of Enalapril and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients Unknown status NCT01041963 Phase 4 Enalapril;Enalapril plus Losartan;Placebo
6 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Unknown status NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
7 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis Unknown status NCT01820026 Phase 4 Imipenem;Vancomycin;azithromycin;Cefotaxime;Amoxicillin
8 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
9 The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding Unknown status NCT02385422 Phase 4 Carvedilol;Propranolol
10 Prospective Comparison of Primary Abdominal Closure and Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
11 Comparing Cefepime Versus Cefazolin Plus Ceftazidime for CAPD-associated Peritonitis Completed NCT02872038 Phase 4 Cefepime;Cefazolin plus Ceftazidime
12 Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis Completed NCT01817309 Phase 4
13 Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis Completed NCT01044446 Phase 4 Icodextrin;glucose-based peritoneal dialysate
14 IV Antibiotics With Lavage for Severe PD Peritonitis Completed NCT02926846 Phase 4 Intravenous vancomycin & gentamicin with adjunctive lavage;Intraperitoneal vancomycin & gentamicin
15 Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention Completed NCT01542801 Phase 4 Norfloxacin;ciprofloxacin
16 Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis Completed NCT00359853 Phase 4 Oral norfloxacin
17 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
18 Comparison of Efficacy of Cefotaxime, Ceftriaxone, and Ciprofloxacin for the Treatment of SBP in Patients With LC Completed NCT01265173 Phase 4 Cefotaxime;Ceftriaxone;Ciprofloxacin
19 Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD. Completed NCT00255619 Phase 4
20 Beneficial Effect of Probiotics on Chronic Kidney Disease Completed NCT01391468 Phase 4
21 Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery Completed NCT00488904 Phase 4
22 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
23 Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children Completed NCT01632046 Phase 4 lactate and bicarbonate buffered dialysis solutions
24 Use of Ointments in Prevention of Catheter Related Infections in PD Completed NCT00400595 Phase 4 Mupirocin ointment;Polysporin Triple
25 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
26 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial Completed NCT01760967 Phase 4 Dexmedetomidine
27 COMPRES - COMpression Anastomosis Ring (CAR™ 27/ColonRing™) Post maRketing Evaluation Study Completed NCT01091155 Phase 4
28 T.E.A. Study Three Days Ertapenem Versus Three Days Ampicillin- Sulbactam Completed NCT00630513 Phase 4 Ertapenem;Ampicillin-Sulbactam
29 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
30 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
31 A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection Completed NCT01721408 Phase 4 Tigecycline;Imipenem/cilastatin
32 Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques Completed NCT01463540 Phase 4
33 Effect of Glucose Degradation Products (GDP) on Endothelial Dysfunction Completed NCT01315314 Phase 4 Balance, Fresenius Medical Care, Germany
34 Non Operative Treatment for Acute Appendicitis Completed NCT01096927 Phase 4 Amoxicillin and Clavulanic Acid
35 The Effect of Neutral Peritoneal Dialysis (PD) Solution With Minimal Glucose-Degradation-Product (GDP) on Fluid Status and Body Composition Completed NCT00966615 Phase 4
36 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection Completed NCT02247414 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
37 Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis Recruiting NCT02805049 Phase 4 Echinocandins
38 PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM) Recruiting NCT02277262 Phase 4
39 The Efficacy of Prolonged Antibiotic Therapy for the Prevention of Relapsing Peritonitis in Peritoneal Dialysis Patients With High Dialysis Effluent Bacterial DNA Fragment Levels Recruiting NCT02593201 Phase 4 Extended antibiotics (cefazolin or ceftazidime);Usual antibiotics (cefazolin or ceftazidime)
40 FEcal Transplant, a Hope to Eradicate Colonization of Patient Harboring eXtreme Drug Resistant Bacteria? Recruiting NCT03029078 Phase 4 fecal microbiota transplant
41 Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection Recruiting NCT02547103 Phase 4
42 Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis Recruiting NCT02308111 Phase 4 Obeticholic Acid (OCA);Placebo
43 The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding Recruiting NCT02695732 Phase 4 Carvedilol
44 G-CSF Plus NAC In Severe Alcoholic Hepatitis Recruiting NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
45 Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation Recruiting NCT03148002 Phase 4 Current Bowel Protocol (senna/lactulose);PEG Bowel Protocol (PEG/lactulose)
46 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy Recruiting NCT02238444 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
47 Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children Recruiting NCT02848820 Phase 4 Augmentin + Gentamicin
48 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites Recruiting NCT02755701 Phase 4 Branched-chain Amino Acid;Placebo
49 Safety and Effectiveness Evaluation of Two Kinds of Peritoneal Dialysate Recruiting NCT01779557 Phase 4 Huaren Peritoneal Dialysate;Baxter Peritoneal Dialysate
50 Efficacy and Safety of a Double Icodextrin Dose in Elderly Incident CAPD Patients on Incremental PD. Recruiting NCT01944852 Phase 4 Icodextrin

Search NIH Clinical Center for Peritonitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :
Sources

Genetic Tests for Peritonitis

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Sources

Anatomical Context for Peritonitis

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MalaCards organs/tissues related to Peritonitis:

41
Liver, Colon, Kidney, Endothelial, Neutrophil, Monocytes, Testes
Sources

Publications for Peritonitis

About this section

Articles related to Peritonitis:

(show top 50) (show all 5278)
# Title Authors Year
1
Disseminated Peritoneal Leiomyomatosis. ( 29959641 )
2018
2
A RETROSPECTIVE ANALYSIS OF ETIOLOGY AND OUTCOMES OF REFRACTORY CAPD PERITONITIS IN A TERTIARY CARE CENTER FROM NORTH INDIA. ( 29386307 )
2018
3
Parasitic Appendicitis: A Novel Laparoscopic Approach for the Prevention of Peritoneal Contamination. ( 29977414 )
2018
4
Photobiomodulation reduces neutrophil migration and oxidative stress in mice with carrageenan-induced peritonitis. ( 29951878 )
2018
5
Peritoneal dialysis-related peritonitis: challenges and solutions. ( 29928142 )
2018
6
Atrial Fibrillation Characteristics in Patients on Haemodialysis vs. Peritoneal Dialysis. ( 29445225 )
2018
7
The effect of periodontal disease treatment in patients with continuous ambulatory peritoneal dialysis. ( 29926368 )
2018
8
Outcome of autosomal dominant polycystic kidney disease patients on peritoneal dialysis: a national retrospective study based on two French registries (the French Language Peritoneal Dialysis Registry and the French Renal Epidemiology and Information Network). ( 29361078 )
2018
9
Meta-analysis of surgical strategies in perforated left colonic diverticulitis with generalized peritonitis. ( 29931505 )
2018
10
MR imaging features of peritoneal alveolar echinococcosis. ( 29580747 )
2018
11
High serum leptin level is associated with peripheral artery disease in adult peritoneal dialysis patients. ( 29875588 )
2018
12
Tracking Competent Host Defence to Chronic Inflammation: An In Vivo Model of Peritonitis. ( 29322409 )
2018
13
Double peritoneal fat flap in the treatment of an enterovesical fistula. ( 29256140 )
2018
14
Adhesive intestinal obstruction increases the risk of intestinal perforation in peritoneal dialysis patients: a case report. ( 29954334 )
2018
15
Secondary peritonitis: principles of diagnosis and intervention. ( 29914871 )
2018
16
Immunosuppression Induced by Perioperative Peritonitis Promotes Lung Metastasis. ( 29970570 )
2018
17
Mesothelin and osteopontin as circulating markers of diffuse malignant peritoneal mesothelioma: A preliminary study. ( 29503128 )
2018
18
Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model. ( 29797583 )
2018
19
Disseminated peritoneal leiomyomatosis (DPL): a case report. ( 29620425 )
2018
20
Utilization of an Alternative Docetaxel-based Intraperitoneal Chemotherapy Regimen in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma: A Continued Need for Ovarian Cancer Patients. ( 29782365 )
2018
21
Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome. ( 29888270 )
2018
22
OUTCOMES OF<i>ACINETOBACTER</i>PERITONITIS IN PERITONEAL DIALYSIS PATIENTS: A MULTICENTER REGISTRY ANALYSIS. ( 29437143 )
2018
23
Authors reply: Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis-the risk of overtreatment. ( 29980887 )
2018
24
Polymicrobial Anaerobic Bacteremia Caused by Butyricimonas virosa and Brachyspira pilosicoli in a Patient with Peritonitis following Intestinal Perforation. ( 29071824 )
2018
25
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in seven patients with peritoneal sarcomatosis from uterine sarcoma. ( 29881584 )
2018
26
Unusual Cause of Peritonitis in Peritoneal Dialysis: Streptococcus vestibularis. ( 29377513 )
2018
27
Pooled analysis of 163 published tuberculous peritonitis cases from Turkey ( 29714445 )
2018
28
Outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma and predictors of survival. ( 29431036 )
2018
29
A rare case of peritonitis due to <i>Brevundimonas vesicularis</i>. ( 29915660 )
2018
30
A case of peritoneal malignant mesothelioma following radiation therapy for cervical cancer. ( 29435293 )
2018
31
Immunohistochemistry in Peritoneal Mesothelioma: A Single-Center Experience of 244 Cases. ( 29048219 )
2018
32
Fecal peritonitis in aging rat model. Therapeutic response to different antibiotic strategies. ( 29924208 )
2018
33
Comment to: Pre-peritoneal local anaesthetic does not reduce post-operative pain in laparoscopic total extra-peritoneal inguinal hernia repair: double-blinded randomized controlled trial. Kulasegaran S, Rohan M, Pearless L, Hulme-Moir M. ( 29356910 )
2018
34
Malignant Peritoneal Mesothelioma: National Practice Patterns, Outcomes, and Predictors of Survival. ( 29721724 )
2018
35
Tuberculous peritonitis and pleurisy accompanied by pulmonary cryptococcosis: A case report. ( 29756504 )
2018
36
Benign multicystic peritoneal mesothelioma treated with laparoendoscopic single site surgery: a case report and review of the literature. ( 29372166 )
2018
37
Exit Site Infection due to Mycobacterium chelonae in an Elderly Patient on Peritoneal Dialysis. ( 29594145 )
2018
38
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT. ( 29443079 )
2018
39
Barium peritonitis with abdominal abscessation. ( 29923195 )
2018
40
New intra-abdominal mass after operation for colorectal cancer: desmoid tumor versus peritoneal seeding. ( 29550958 )
2018
41
Sclerosing encapsulating peritonitis after living-donor liver transplantation: A case series, Kyoto experience. ( 29896575 )
2018
42
A Rare Colonization in the Peritonitis Following Blunt Abdominal Trauma. ( 29449198 )
2018
43
The impact of chemotherapy and its timing on survival in malignant peritoneal mesothelioma treated with complete debulking. ( 29651664 )
2018
44
Low density neutrophils (LDN) in postoperative abdominal cavity assist the peritoneal recurrence through the production of neutrophil extracellular traps (NETs). ( 29330531 )
2018
45
Peritoneal Myeloid Sarcoma in a Patient Treated for a Testicular Seminoma. ( 29955031 )
2018
46
Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis: the risk of overtreatment. ( 29948522 )
2018
47
Microbiology and antibiotic susceptibility patterns in spontaneous bacterial peritonitis: A study of two Dutch cohorts at a 10-year interval. ( 29881617 )
2018
48
Clinical and microbiological characteristics of peritoneal dialysis-related peritonitis caused by Escherichia coli in southern Taiwan. ( 29931659 )
2018
49
Prognostic significance of peritoneal lavage cytology in staging gastric cancer: systematic review and meta-analysis. ( 28779261 )
2018
50
Malignant peritoneal mesothelioma in a woman with bilateral ovarian serous borderline tumour: Potential interactions between the two diseases. ( 29915796 )
2018
Sources

Variations for Peritonitis

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ClinVar genetic disease variations for Peritonitis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 TMEM67 NM_153704.5(TMEM67): c.1843T> C (p.Cys615Arg) single nucleotide variant Pathogenic/Likely pathogenic rs201893408 GRCh37 Chromosome 8, 94808198: 94808198
2 TMEM67 NM_153704.5(TMEM67): c.1843T> C (p.Cys615Arg) single nucleotide variant Pathogenic/Likely pathogenic rs201893408 GRCh38 Chromosome 8, 93795970: 93795970
3 TMEM67 NM_153704.5(TMEM67): c.1321C> T (p.Arg441Cys) single nucleotide variant Pathogenic/Likely pathogenic rs752362727 GRCh38 Chromosome 8, 93786255: 93786255
4 TMEM67 NM_153704.5(TMEM67): c.1321C> T (p.Arg441Cys) single nucleotide variant Pathogenic/Likely pathogenic rs752362727 GRCh37 Chromosome 8, 94798483: 94798483
Sources

Expression for Peritonitis

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Search GEO for disease gene expression data for Peritonitis.
Sources

Pathways for Peritonitis

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Pathways related to Peritonitis according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 66
Show member pathways
 14.09 B2M CCL2 CRP CXCL8 ICAM1 IL10
2
TGF-Beta Pathway 64
Show member pathways
 13.56 CCL2 CXCL8 F2 IL10 IL1B IL6
3
Akt Signaling 64
Show member pathways
 13.46 CCL2 CXCL8 IL10 IL1B IL6 ITGAM
4
Cytokine Signaling in Immune system 66
Show member pathways
 13.45 B2M CCL2 CXCL8 ICAM1 IL10 IL1B
5
Toll-like Receptor Signaling Pathway 37 1
Show member pathways
 13.07 CCL2 CXCL8 IL10 IL1B IL6 LBP
6
Allograft rejection 1 37
Show member pathways
 12.96 B2M CXCL8 ICAM1 IL10 IL1B IL6
7
Influenza A 37
Show member pathways
 12.89 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
8
Regulation of IFNA signaling 66
Show member pathways
 12.7 CXCL8 IL10 IL1B IL6 TNF
9
Immune response IL-23 signaling pathway 22
Show member pathways
 12.69 CCL2 F2 IL10 IL1B IL6 MPO
10
NF-kappaB Signaling 4
12.67 B2M CCL2 IL10 IL1B MPO TLR2
11
Kaposi's sarcoma-associated herpesvirus infection 37
Show member pathways
 12.63 CXCL8 ICAM1 IL6 TLR2 TNF
12
Th17 cell differentiation 37
Show member pathways
 12.51 IL10 IL1B IL6 TLR2 TNF
13
IL-17 Family Signaling Pathways 65
Show member pathways
 12.45 CCL2 CXCL8 IL1B IL6 TLR2 TNF
14
T cell receptor signaling pathway 37
Show member pathways
 12.44 IL10 IL1B IL6 TNF
15
Toll Comparative Pathway 64
Show member pathways
 12.36 CXCL8 IL1B IL6 LBP TNF
16
Th1 Differentiation Pathway 65
Show member pathways
 12.35 IL10 IL1B IL6 TLR2 TNF
17
Toxoplasmosis 37
Show member pathways
 12.34 IL10 IL1B ITGAM TLR2 TNF
18
Diseases associated with the TLR signaling cascade 66
Show member pathways
 12.31 CXCL8 IL6 TLR2 TNF
19
IL-1 Family Signaling Pathways 65
Show member pathways
 12.31 CXCL8 IL1B IL6 TLR2 TNF
20
Tuberculosis 37
12.31 IL10 IL1B IL6 ITGAM LBP TLR2
21
Transcriptional misregulation in cancer 37
12.29 CXCL8 IL6 ITGAM MPO
22
Bacterial infections in CF airways 22
Show member pathways
 12.29 CXCL8 IL1B IL6 LBP TLR2 TNF
23
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
12.27 CXCL8 IL10 IL1B IL6 TNF
24
C-type lectin receptor signaling pathway 37
Show member pathways
 12.26 IL10 IL1B IL6 TNF
25
Folate Metabolism 1
Show member pathways
 12.24 ALB CCL2 CRP F2 ICAM1 IL1B
26
Immune response IFN gamma signaling pathway 22
Show member pathways
 12.17 CCL2 CXCL8 ICAM1 IL10 IL1B IL6
27
Fluid shear stress and atherosclerosis 37
12.15 CCL2 ICAM1 IL1B TNF
28
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
12.12 IL10 IL6 ITGAM MPO TNF
29
TNF signaling pathway 37
12.08 CCL2 ICAM1 IL1B IL6 TNF
30
Spinal Cord Injury 1
12.08 AQP1 CCL2 CXCL8 ICAM1 IL1B IL6
31
NF-kappa B signaling pathway 37
12.01 CXCL8 ICAM1 IL1B LBP TNF
32
AGE-RAGE signaling pathway in diabetic complications 37
12.01 CCL2 CXCL8 ICAM1 IL1B IL6 TNF
33
Hematopoietic cell lineage 37
11.98 IL1B IL6 ITGAM TNF
34
Cytokine production by Th17 cells in CF (Mouse model) 22
Show member pathways
 11.96 CXCL8 ICAM1 IL6 LBP
35
Salmonella infection (KEGG) 37
11.92 CXCL8 IL1B IL6 LBP
36
Innate Lymphoid Cell Differentiation Pathways 65
11.89 IL10 IL1B ITGAM TNF
37
Amoebiasis 37
11.89 CXCL8 IL10 IL1B IL6 ITGAM TLR2
38
Dendritic Cells Developmental Lineage Pathway 65
11.87 IL10 IL1B IL6 ITGAM TNF
39
Pertussis 37
11.85 CXCL8 IL10 IL1B IL6 ITGAM TNF
40
IL6-mediated signaling events 1
Show member pathways
 11.84 CRP IL6 LBP
41
Glucocorticoid receptor regulatory network 1
11.82 CXCL8 ICAM1 IL6
42
Rheumatoid arthritis 37
11.82 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
43
Lung fibrosis 1
11.78 CCL2 CXCL8 IL1B IL6 TNF
44
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.77 CXCL8 ICAM1 IL1B IL6 TNF
45
Interleukin-4 and 13 signaling 66
11.67 CCL2 CXCL8 ICAM1 IL10 IL1B IL6
46
Staphylococcus aureus infection 37
11.65 ICAM1 IL10 ITGAM
47
Legionellosis 37
11.65 CXCL8 IL1B IL6 ITGAM TLR2 TNF
48
amb2 Integrin signaling 1
11.64 ICAM1 IL6 ITGAM MPO TNF
49
MSP-RON Signaling 64
11.63 CCL2 IL1B ITGAM TLR2 TNF
50
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
11.54 IL1B IL6 TNF
Sources

GO Terms for Peritonitis

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Cellular components related to Peritonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.8 ADA B2M ICAM1 ITGAM LBP TLR2
2 extracellular region GO:0005576 9.77 ALB B2M CCL2 CRP CXCL8 F2
3 membrane raft GO:0045121 9.67 ICAM1 ITGAM TLR2 TNF
4 external side of plasma membrane GO:0009897 9.63 ADA B2M F2 ICAM1 ITGAM TNF
5 extracellular space GO:0005615 9.53 ADA ALB B2M CCL2 CRP CXCL8
6 extracellular exosome GO:0070062 10.06 ALB AQP1 B2M CRP F2 ICAM1

Biological processes related to Peritonitis according to GeneCards Suite gene sharing:

(show all 49)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.99 IL10 LBP MPO TNF
2 cellular protein metabolic process GO:0044267 9.99 ALB B2M F2 IL6
3 leukocyte migration GO:0050900 9.98 F2 ICAM1 IL1B ITGAM TNF
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.96 ICAM1 IL1B IL6 TLR2 TNF
5 defense response to Gram-positive bacterium GO:0050830 9.91 CRP IL6 LBP TLR2 TNF
6 positive regulation of DNA binding transcription factor activity GO:0051091 9.89 IL10 IL1B IL6 TNF
7 cellular response to interleukin-1 GO:0071347 9.87 CCL2 CXCL8 ICAM1
8 response to insulin GO:0032868 9.87 ICAM1 IL10 TLR2
9 cellular response to organic cyclic compound GO:0071407 9.87 CCL2 IL1B TNF
10 response to lipopolysaccharide GO:0032496 9.87 CXCL8 ICAM1 IL10 IL1B LBP MPO
11 neutrophil chemotaxis GO:0030593 9.86 CCL2 CXCL8 IL1B
12 response to glucocorticoid GO:0051384 9.85 IL10 IL6 TNF
13 humoral immune response GO:0006959 9.84 CCL2 IL6 TNF
14 acute-phase response GO:0006953 9.83 CRP F2 IL6 LBP
15 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.82 IL1B TLR2 TNF
16 protein kinase B signaling GO:0043491 9.81 CCL2 IL1B TNF
17 positive regulation of nitric oxide biosynthetic process GO:0045429 9.81 ICAM1 IL1B TNF
18 positive regulation of interleukin-8 production GO:0032757 9.8 IL1B LBP TLR2 TNF
19 positive regulation of interleukin-6 production GO:0032755 9.8 IL1B IL6 LBP TLR2 TNF
20 positive regulation of chemokine production GO:0032722 9.76 IL6 LBP TLR2 TNF
21 embryonic digestive tract development GO:0048566 9.75 ADA