MCID: PRV005
MIFTS: 31

Perivascular Tumor

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Perivascular Tumor

MalaCards integrated aliases for Perivascular Tumor:

Name: Perivascular Tumor 12 15
Malignant Perivascular Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3316
NCIt 50 C6528 C6530
UMLS 70 C1334611 C1335392

Summaries for Perivascular Tumor

MalaCards based summary : Perivascular Tumor, also known as malignant perivascular cancer, is related to benign perivascular tumor and glomangiomatosis. An important gene associated with Perivascular Tumor is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Hematopoietic cell lineage and Transcriptional misregulation in cancer. Affiliated tissues include endothelial, lymph node and ovary, and related phenotypes are behavior/neurological and cellular

Related Diseases for Perivascular Tumor

Diseases in the Perivascular Tumor family:

Benign Perivascular Tumor

Diseases related to Perivascular Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 300)
# Related Disease Score Top Affiliating Genes
1 benign perivascular tumor 31.5 SYP PECAM1 MLANA KIT GLMN CD34
2 glomangiomatosis 31.4 SYP PECAM1 MLANA KIT CD34 CALD1
3 glomus tumor 29.9 SYP GLMN CD34 CALD1
4 pericytoma with t(7;12) 11.0
5 penis sarcoma 10.4 MLANA CD34
6 ovarian melanoma 10.4 MLANA CALD1
7 pulmonary vein leiomyosarcoma 10.4 CD34 CALD1
8 spinal cord sarcoma 10.4 KIT CD34
9 lentigo maligna melanoma 10.4 MLANA MITF
10 gallbladder leiomyoma 10.4 KIT CD34
11 ceruminous adenocarcinoma 10.4 SLC2A1 KIT
12 peritoneal benign neoplasm 10.4 CD34 CALD1
13 epidural spinal canal neoplasm 10.4 MLANA CD34
14 pigmented basal cell carcinoma 10.4 MLANA MITF
15 malignant anus melanoma 10.4 MLANA KIT
16 prostate embryonal rhabdomyosarcoma 10.4 KIT CALD1
17 malignant dermis tumor 10.4 MLANA KIT
18 sarcomatoid transitional cell carcinoma 10.4 SYP MLANA
19 benign fibrous mesothelioma 10.4 KIT CD34
20 lung meningioma 10.4 SYP CD34
21 malignant skin fibrous histiocytoma 10.4 MLANA KIT
22 adult fibrosarcoma 10.4 CD34 CALD1
23 optic nerve astrocytoma 10.4 TSC2 SYP
24 liver fibroma 10.4 KIT CD34
25 vaginal endometrial stromal tumor 10.4 MME CALD1
26 vulvar melanoma 10.4 MLANA KIT
27 mixed endometrial stromal and smooth muscle tumor 10.4 MME CALD1
28 testicular fibroma 10.4 CD34 CALD1
29 cervical serous adenocarcinoma 10.4 MME MLANA
30 sensory organ benign neoplasm 10.4 SYP MLANA
31 breast leiomyoma 10.4 MME CD34
32 epithelioid cell melanoma 10.4 MLANA MITF
33 pineal region teratoma 10.4 SYP KIT
34 subareolar duct papillomatosis 10.4 MME CALD1
35 plexiform schwannoma 10.4 KIT CD34
36 skin epithelioid hemangioma 10.4 PECAM1 CD34
37 cervical mucinous adenocarcinoma 10.4 MME CALD1
38 nipple benign neoplasm 10.4 MME CALD1
39 aortic malignant tumor 10.4 PECAM1 CD34
40 laryngeal small cell carcinoma 10.4 SYP KIT
41 congenital granular cell tumor 10.4 CD34 CALD1
42 prostate angiosarcoma 10.4 PECAM1 CD34
43 central nervous system angiosarcoma 10.4 PECAM1 CD34
44 vulvar leiomyosarcoma 10.4 MLANA CD34 CALD1
45 cutaneous leiomyosarcoma 10.4 CD34 CALD1
46 malignant choroid melanoma 10.4 MLANA MITF
47 central nervous system hemangioma 10.4 PECAM1 CD34
48 infiltrating angiolipoma 10.4 MLANA CD34 CALD1
49 heart fibrosarcoma 10.3 PECAM1 CD34
50 ovarian angiosarcoma 10.3 PECAM1 CD34

Graphical network of the top 20 diseases related to Perivascular Tumor:



Diseases related to Perivascular Tumor

Symptoms & Phenotypes for Perivascular Tumor

MGI Mouse Phenotypes related to Perivascular Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.07 ANO1 ASPSCR1 CTSK KIT MITF MME
2 cellular MP:0005384 9.9 CD34 CTSK GLMN KIT MITF MME
3 integument MP:0010771 9.7 ANO1 CD34 KIT MITF MLANA MME
4 pigmentation MP:0001186 9.1 KIT MITF MLANA TFE3 TFEB TSC1

Drugs & Therapeutics for Perivascular Tumor

Search Clinical Trials , NIH Clinical Center for Perivascular Tumor

Genetic Tests for Perivascular Tumor

Anatomical Context for Perivascular Tumor

MalaCards organs/tissues related to Perivascular Tumor:

40
Endothelial, Lymph Node, Ovary, Uterus, Prostate, Pineal

Publications for Perivascular Tumor

Articles related to Perivascular Tumor:

(show top 50) (show all 90)
# Title Authors PMID Year
1
Imaging features of myopericytoma of the breast: A case report and review of the literature. 61
33204380 2021
2
Niche-derived soluble DLK1 promotes glioma growth. 61
33142235 2020
3
Intercellular delivery of bioorthogonal chemical receptors for enhanced tumor targeting and penetration. 61
32827798 2020
4
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma. 61
32205867 2020
5
Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma. 61
31880322 2020
6
Immune stromal features in cervical squamous cell carcinoma are prognostic factors for distant metastasis: A retrospective study. 61
31776057 2020
7
A rare pericytic tumor of the kidney: The first case in Korea. 61
31855704 2020
8
Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma. 61
31906065 2019
9
Can we ablate liver lesions close to large portal and hepatic veins with MR-guided HIFU? An experimental study in a porcine model. 61
30737565 2019
10
[Clinicopathological study of BCOR rearrangement in high grade endometrial stromal sarcoma]. 61
31422590 2019
11
Blood Vessel Proximity Shapes Cancer Cell Metabolism. 61
31269424 2019
12
Expression of GLUT1 in Pseudopalisaded and Perivascular Tumor Cells Is an Independent Prognostic Factor for Patients With Glioblastomas. 61
30990881 2019
13
Transvenous Biopsy in the Diagnosis of Intravascular or Perivascular Neoplasm: A Single-Center Retrospective Analysis of 36 Patients. 61
30409475 2019
14
A Case of Glomangiopericytoma at the Nasal Septum. 61
29168109 2018
15
Percutaneous ablation for perivascular hepatocellular carcinoma: Refining the current status based on emerging evidence and future perspectives. 61
30598578 2018
16
Perivascular Tumor-Infiltrating Leukocyte Scoring for Prognosis of Resected Hepatocellular Carcinoma Patients. 61
30340430 2018
17
Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumors. 61
30016073 2018
18
Hemorrhagic Brain Metastases in a Patient with Anaplastic Lymphoma Kinase (ALK)-Rearranged Invasive Mucinous Adenocarcinoma of the Lung. 61
29371584 2018
19
Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival. 61
28912141 2017
20
CD44 Interacts with HIF-2α to Modulate the Hypoxic Phenotype of Perinecrotic and Perivascular Glioma Cells. 61
28813675 2017
21
Digital Myopericytoma: A Case Report and Systematic Literature Review. 61
28442859 2017
22
Myopericytoma arising adjacent to the common carotid artery: Case report and systematic review of deep located neck myopericytomas. 61
27061437 2016
23
Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer. 61
27139518 2016
24
Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells. 61
27270311 2016
25
Preliminary Outcome of Microwave Ablation of Hepatocellular Carcinoma: Breaking the 3-cm Barrier? 61
27013403 2016
26
Pericyte Antigens in Perivascular Soft Tissue Tumors. 61
26085647 2015
27
Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts. 61
26172285 2015
28
Myopericytoma of the hypothenar eminence: case report. 61
26034459 2015
29
Renal hemangiopericytoma: case report and literature review. 61
25946050 2015
30
Solitary fibrous tumor/hemangiopericytoma of the penis: Report of the first case. 61
25363038 2015
31
Renal hemangiopericytoma secondary to refractory hypertension in a child: A case report. 61
25364414 2014
32
Primary and metastatic renal hemangiopericytoma. 61
25306989 2014
33
From pericytes to perivascular tumours: correlation between pathology, stem cell biology, and tissue engineering. 61
24566993 2014
34
Cripto-1 expression in glioblastoma multiforme. 61
24521322 2014
35
Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle. 61
24650559 2014
36
CT angiography findings in carotid blowout syndrome and its role as a predictor of 1-year survival. 61
23969344 2014
37
An atypical presentation of myopericytoma in palmar arch and review of the literature. 61
25349759 2014
38
Hemangiopericytoma of the uterus: a rare case of pelvic mass. 61
25509980 2014
39
Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target? 61
24396516 2013
40
The functionalized human serine protease granzyme B/VEGF₁₂₁ targets tumor vasculature and ablates tumor growth. 61
23858102 2013
41
Irreversible electroporation of a hepatocellular carcinoma lesion adjacent to a transjugular intrahepatic portosystemic shunt stent graft. 61
24043975 2013
42
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies. 61
23918357 2013
43
Prognostic significance of the aggregative perivascular growth pattern of tumor cells in primary central nervous system diffuse large B-cell lymphoma. 61
23482670 2013
44
Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models. 61
22989076 2013
45
Nanocarrier-mediated targeting of tumor and tumor vascular cells improves uptake and penetration of drugs into neuroblastoma. 61
23936762 2013
46
AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes. 61
24086629 2013
47
Evaluation of the antiangiogenic effect of Kringle 1-5 in a rat glioma model. 61
21796002 2012
48
Rectal hemangiopericytoma in a 37-year-old woman: a case report and review of the literature. 61
21819590 2011
49
Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells. 61
21597001 2011
50
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. 61
20346382 2010

Variations for Perivascular Tumor

Expression for Perivascular Tumor

Search GEO for disease gene expression data for Perivascular Tumor.

Pathways for Perivascular Tumor

Pathways related to Perivascular Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.43 MME KIT CD34
2 11.21 TFE3 PRCC MITF ASPSCR1
3 11.2 MME KIT CD34
4 10.96 TFEB TFE3 MITF

GO Terms for Perivascular Tumor

Cellular components related to Perivascular Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.83 TSC2 TSC1 TFEB TFE3 SLC2A1 SFPQ
2 integral component of plasma membrane GO:0005887 9.8 SLC2A1 PECAM1 MME MLANA KIT CD34
3 membrane raft GO:0045121 9.46 SLC2A1 PECAM1 MME ANO1
4 TSC1-TSC2 complex GO:0033596 8.62 TSC2 TSC1

Biological processes related to Perivascular Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of osteoclast differentiation GO:0045670 9.16 TFE3 MITF
2 neural tube closure GO:0001843 9.13 TSC2 TSC1 GLMN
3 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Molecular functions related to Perivascular Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.62 TSC2 TSC1 TFEB TFE3 SYP SLC2A1
2 protein dimerization activity GO:0046983 9.46 TFEB TFE3 MITF ANO1
3 protein homodimerization activity GO:0042803 9.43 TSC2 SFPQ PECAM1 MME KIT ANO1

Sources for Perivascular Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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