MCID: PRN016
MIFTS: 32

Peroneal Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Peroneal Neuropathy

MalaCards integrated aliases for Peroneal Neuropathy:

Name: Peroneal Neuropathy 12 15
Peroneal Neuropathies 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4201
MeSH 44 D020427
NCIt 50 C27596
UMLS 73 C0747533

Summaries for Peroneal Neuropathy

MalaCards based summary : Peroneal Neuropathy, also known as peroneal neuropathies, is related to neuropathy and orbital plasma cell granuloma. An important gene associated with Peroneal Neuropathy is EDN2 (Endothelin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Transcription_NF-kB signaling pathway. The drug Complement System Proteins has been mentioned in the context of this disorder. Affiliated tissues include liver, testes and bone.

Related Diseases for Peroneal Neuropathy

Diseases related to Peroneal Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 neuropathy 10.7
2 orbital plasma cell granuloma 10.2 MME TNFRSF1B
3 streptococcal meningitis 10.1 EDN2 TNF
4 chronic orbital inflammation 10.1 MME TNFRSF1B
5 spermatocele 10.0 MME TNF
6 skin sarcoidosis 10.0 TNF TNFRSF1B
7 rheumatoid lung disease 10.0 TNF TNFRSF1B
8 foot drop 10.0
9 chronic gonococcal salpingitis 10.0 TNF TNFRSF1B
10 scleral disease 10.0 TNF TNFRSF1B
11 pustulosis of palm and sole 10.0 TNF TNFRSF1B
12 periodic fever, familial, autosomal dominant 10.0 TNF TNFRSF1B
13 sweat gland disease 10.0 TNF TNFRSF1B
14 acute salpingitis 9.9 TNF TNFRSF1B
15 peroneal nerve, accessory deep 9.9
16 radiculopathy 9.9
17 aneurysm 9.9
18 post-transplant lymphoproliferative disease 9.9 TNF TNFRSF1B
19 chronic salpingitis 9.9 TNF TNFRSF1B
20 panuveitis 9.8 TNF TNFRSF1B
21 palindromic rheumatism 9.8 TNF TNFRSF1B
22 hypersensitivity reaction type iv disease 9.8 TNF TNFRSF1B
23 varicose veins 9.8
24 aging 9.8
25 burns 9.8
26 crohn's disease 9.8
27 endocarditis 9.8
28 tetanus 9.8
29 mononeuropathy 9.8
30 pigmented villonodular synovitis 9.8
31 synovitis 9.8
32 anterior compartment syndrome 9.8
33 paraplegia 9.8
34 compartment syndrome 9.8
35 neuronitis 9.8
36 villonodular synovitis 9.8
37 hansen's disease 9.8
38 spasticity 9.8
39 exanthem 9.8 TNF TNFRSF1B
40 complex regional pain syndrome 9.7 MME TNF
41 cogan syndrome 9.7 TNF TNFRSF1B
42 guillain-barre syndrome 9.6 TNF TNFRSF1B
43 peroneal nerve paralysis 9.6 CPN1 EDN2 ELF2
44 spondyloarthropathy 1 9.5 TNF TNFRSF1B
45 primary bacterial infectious disease 9.2 TNF TNFRSF1B

Graphical network of the top 20 diseases related to Peroneal Neuropathy:



Diseases related to Peroneal Neuropathy

Symptoms & Phenotypes for Peroneal Neuropathy

Drugs & Therapeutics for Peroneal Neuropathy

Drugs for Peroneal Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822
2 Treating Foot Drop in People With Multiple Sclerosis Using Electrical Stimulation Completed NCT02123537 Not Applicable
3 Walking With FES or AFO in People With MS With Foot Drop Completed NCT01977287
4 High-resolution Ultrasound in Lower Extremity Nerves and Common Fibular Neuropathies. Recruiting NCT03560505
5 Ankle Robot to Reduce Foot Drop in Stroke Recruiting NCT02483676 Not Applicable
6 Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03556709 Not Applicable
7 Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03530592 Not Applicable
8 The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop Terminated NCT01001390 Not Applicable

Search NIH Clinical Center for Peroneal Neuropathy

Cochrane evidence based reviews: peroneal neuropathies

Genetic Tests for Peroneal Neuropathy

Anatomical Context for Peroneal Neuropathy

MalaCards organs/tissues related to Peroneal Neuropathy:

41
Liver, Testes, Bone

Publications for Peroneal Neuropathy

Articles related to Peroneal Neuropathy:

(show top 50) (show all 81)
# Title Authors Year
1
Causes of peroneal neuropathy associated with orthopaedic leg lengthening in different canine models. ( 29802558 )
2018
2
Common Peroneal Neuropathy With Anterior Tibial Artery Occlusion: A Case Report. ( 28971059 )
2017
3
Late peroneal neuropathy following open surgical treatment of politeal artery aneurysm. ( 28947218 )
2017
4
Seiza-induced neuropathy: an occupational peroneal neuropathy in a Japanese lady. ( 28409244 )
2017
5
Explaining peroneal neuropathy after ankle sprain. ( 28456862 )
2017
6
Median and common peroneal neuropathy in coir workers of Alappuzha district, Kerala. ( 28298838 )
2017
7
Peroneal neuropathy in giant cell arteritis. ( 28028163 )
2017
8
A Proximally Based Sural Fasciocutaneous Flap for the Treatment of Recurrent Peroneal Neuropathy: A Case Report. ( 27536494 )
2016
9
Role of Sonography in the Diagnosis and Treatment of Common Peroneal Neuropathy Secondary to Fabellae. ( 26782165 )
2016
10
Subclinical Peroneal Neuropathy: A Common, Unrecognized, and Preventable Finding Associated With a Recent History of Falling in Hospitalized Patients. ( 28376439 )
2016
11
Sonographic evaluation of common peroneal neuropathy in patients with foot drop. ( 25792587 )
2015
12
Early detection of peroneal neuropathy by ultrasound. ( 24600072 )
2014
13
Isolated superficial peroneal neuropathy: a rare presentation of Hansen's disease (Leprosy). ( 24939189 )
2014
14
An unusual cause of peroneal neuropathy. ( 25149929 )
2014
15
Ganglion cyst at the fibular head causing common peroneal neuropathy diagnosed with ultrasound and electrodiagnostic examination: a case report. ( 24919081 )
2014
16
Association between the use of gel pads under patients' knees and the incidence of peroneal neuropathy following liver transplantation. ( 25189305 )
2014
17
Editorial comment: An unusual cause of peroneal neuropathy. ( 25149930 )
2014
18
Magnetic resonance neurography in peroneal neuropathy related to sclerotherapy of varicose veins. ( 25347902 )
2014
19
Assessment of hip abductor power in patients with foot drop: a simple and useful test to differentiate lumbar radiculopathy and peroneal neuropathy. ( 22805342 )
2013
20
Fibular (peroneal) neuropathy: electrodiagnostic features and clinical correlates. ( 23177035 )
2013
21
Delayed Onset of Peroneal Neuropathy After Minor Ankle Torsion in a 9-Year-Old Boy. ( 23435281 )
2013
22
Peroneal neuropathy misdiagnosed as L5 radiculopathy: a case report. ( 23618508 )
2013
23
High-resolution 3-T MR neurography of peroneal neuropathy. ( 21416383 )
2012
24
Common fibular (peroneal) neuropathy as the result of a ganglion cyst. ( 23202278 )
2012
25
Common peroneal neuropathy and cancer. ( 22805690 )
2012
26
Atypical presentations of common peroneal neuropathy. ( 22732160 )
2012
27
Acute common peroneal neuropathy due to hand positioning in normal labor and delivery. ( 21768840 )
2011
28
Peroneal neuropathy after tibio-fibular fracture. ( 22506187 )
2011
29
Common peroneal neuropathy related to cryotherapy and compression in a footballer. ( 21253977 )
2011
30
Peroneal neuropathy after weight loss: a high-resolution ultrasonographic characterization of the common peroneal nerve. ( 21534018 )
2011
31
Compression-caused peroneal neuropathy: commentary from a biopsychologist. ( 19996836 )
2010
32
Compression peroneal neuropathy following a bicycle injury in a child. ( 20357722 )
2010
33
An unusual presentation of peroneal neuropathy secondary to pigmented villonodular synovitis: a case report. ( 19205665 )
2009
34
Atypical deep peroneal neuropathy in the setting of an accessory deep peroneal nerve. ( 19609929 )
2009
35
Peroneal neuropathy following liver transplantation: possible predisposing factors and outcome. ( 20353377 )
2009
36
Compound nerve action potential of common peroneal nerve and sural nerve action potential in common peroneal neuropathy. ( 18303210 )
2008
37
Peroneal neuropathy after liver transplantation. ( 18929798 )
2008
38
Evaluation and treatment of peroneal neuropathy. ( 19468889 )
2008
39
Ganglion: an uncommon cause of compressive peroneal neuropathy. ( 18040131 )
2007
40
Bilateral foot drop after intestinal surgery: peroneal neuropathy unabated in elderly patients. ( 17979916 )
2007
41
Common peroneal neuropathy in patients after first-time stroke. ( 18210927 )
2007
42
Peroneal neuropathy due to ground pad burn injury after a radiofrequency ablation surgery. ( 17206480 )
2007
43
Adolescence peroneal neuropathy associated with rapid marked weight reduction: case report and literature review. ( 17166754 )
2007
44
Drop foot in Crohn's disease: reported nadir incidence of peroneal neuropathy. ( 17663426 )
2007
45
High-resolution ultrasound as a diagnostic adjunct in common peroneal neuropathy. ( 18071050 )
2007
46
Peroneal neuropathy following successful bariatric surgery. Case report and review of the literature. ( 17044570 )
2006
47
Practice parameter: utility of electrodiagnostic techniques in evaluating patients with suspected peroneal neuropathy: an evidence-based review. ( 15768387 )
2005
48
MRI detection of cysts of the knee causing common peroneal neuropathy. ( 16344535 )
2005
49
Involvement of superficial peroneal sensory nerve in common peroneal neuropathy. ( 15806552 )
2005
50
Acute onset of deep peroneal neuropathy during a golf game resulting from a ganglion cyst. ( 19078752 )
2004

Variations for Peroneal Neuropathy

Expression for Peroneal Neuropathy

Search GEO for disease gene expression data for Peroneal Neuropathy.

Pathways for Peroneal Neuropathy

Pathways related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.01 LITAF TNF TNFRSF1B
2 10.99 TNF TNFRSF1B
3
Show member pathways
10.85 TNF TNFRSF1B
4 10.65 TNF TNFRSF1B
5 10.13 TNF TNFRSF1B

GO Terms for Peroneal Neuropathy

Biological processes related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.54 EDN2 TNF TNFRSF1B
2 cellular response to lipopolysaccharide GO:0071222 9.33 LITAF TNF TNFRSF1B
3 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.32 TNF TNFRSF1B
4 extrinsic apoptotic signaling pathway GO:0097191 9.26 TNF TNFRSF1B
5 positive regulation of membrane protein ectodomain proteolysis GO:0051044 8.96 TNF TNFRSF1B
6 peptide metabolic process GO:0006518 8.62 CPN1 MME

Sources for Peroneal Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....