MCID: PRN016
MIFTS: 31

Peroneal Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Peroneal Neuropathy

MalaCards integrated aliases for Peroneal Neuropathy:

Name: Peroneal Neuropathy 12 15
Peroneal Neuropathies 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4201
MeSH 44 D020427
NCIt 50 C27596
UMLS 70 C0747533

Summaries for Peroneal Neuropathy

MalaCards based summary : Peroneal Neuropathy, also known as peroneal neuropathies, is related to neuropathy and foot drop. An important gene associated with Peroneal Neuropathy is CTU2 (Cytosolic Thiouridylase Subunit 2), and among its related pathways/superpathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Glycerophospholipid biosynthesis. The drug Complement System Proteins has been mentioned in the context of this disorder. Affiliated tissues include spinal cord, heart and thyroid.

Related Diseases for Peroneal Neuropathy

Graphical network of the top 20 diseases related to Peroneal Neuropathy:



Diseases related to Peroneal Neuropathy

Symptoms & Phenotypes for Peroneal Neuropathy

Drugs & Therapeutics for Peroneal Neuropathy

Drugs for Peroneal Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins

Interventional clinical trials:

(show all 27)
# Name Status NCT ID Phase Drugs
1 Evaluation of the Safety and Performance of the NESS L300 Plus System Completed NCT01237860 Phase 3
2 Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis Completed NCT00872053 Phase 1, Phase 2
3 Comparison of Different Treatment Methods for Gait Rehabilitation of Sub-Acute Post Stroke Patients With Dropped Foot Unknown status NCT01876030
4 Role of Sensory Potentials and High-resolution Ultrasonography in Confirmation of Common Peroneal Mononeuropathy at the Fibular Neck Completed NCT03753178
5 Adaptive Ankle Robot Control System to Reduce Foot-drop in Chronic Stroke Completed NCT02483676
6 The Effect of Ballet Training on Plantar Venous Pump Activity in Ballerinas Completed NCT04469361
7 The Evaluation of Dual Channel vs Single Channel FES for Dropfoot Completed NCT02494323
8 Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot Drop:Feasibility of Instrumented Gait Analysis in Clinical Practice. Completed NCT01914016
9 Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke. Completed NCT02693834
10 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822
11 A Prospective Study of High-resolution Ultrasonography in Examination of Lower Extremity Peripheral Nerves in Patients With Compression Neuropathies and in Healthy Controls. Completed NCT03560505
12 Functional Ambulation: Standard Treatment vs. Electronic Stimulation Therapy (FASTEST)Trial in Chronic Post-Stroke Subjects With Foot Drop Completed NCT01138995
13 A Pilot Study to Assess the Effects of Using FES or AFO as an Assistive Mobility for Period of 12 Weeks for People With Multiple Sclerosis With Foot Drop Completed NCT01977287
14 Identification of Responders to the FES Interventions in Stroke Population Completed NCT01952613
15 Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke Completed NCT02199795
16 Functional Electrical Stimulation to Treat Foot Drop in People With Multiple Sclerosis Completed NCT02123537
17 Identification and Validation of Non-invasive Mechanomyography as a Valuable Predictor of Clinical Course and Long-term Prognosis for Cubital Tunnel Syndrome and Peroneal Nerve Decompression Patients Recruiting NCT04322448
18 Functional Electrical Stimulation of the Ankle Dorsiflexors During Walking in Children With Unilateral Spastic Cerebral Palsy: a Randomized Crossover Intervention Study Recruiting NCT03440632
19 Influence of Whole Body Vibration on Neuromodulation of Ankle Muscles in Persons With SCI Recruiting NCT04238013
20 Multi-pad Functional Electrical Stimulation for Droop Foot Treatment Enrolling by invitation NCT02729636
21 Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03556709
22 Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03530592
23 Portable Ankle Robotics to Reverse Foot Drop After Stroke Not yet recruiting NCT04594837
24 A Prospective, Multi-center, Randomized, Parallel-group Controlled Trial to Compare Conservative Versus Surgical Treatment of Foot Drop in Peroneal Nerve Entrapment. Not yet recruiting NCT04695834
25 The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop Terminated NCT01001390
26 Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee Arthroplasty Withdrawn NCT02856958
27 TREAT Foot Drop After Stroke With Ankle Robot Withdrawn NCT04137809

Search NIH Clinical Center for Peroneal Neuropathy

Cochrane evidence based reviews: peroneal neuropathies

Genetic Tests for Peroneal Neuropathy

Anatomical Context for Peroneal Neuropathy

MalaCards organs/tissues related to Peroneal Neuropathy:

40
Spinal Cord, Heart, Thyroid

Publications for Peroneal Neuropathy

Articles related to Peroneal Neuropathy:

(show top 50) (show all 194)
# Title Authors PMID Year
1
A rare case of parasagittal meningioma causing isolated foot drop: case report and review of the literature. 61
31786742 2021
2
Bilateral common peroneal neuropathy due to rapid and marked weight loss after biliary surgery: A case report. 61
33748241 2021
3
Concurrent Surgical Management of Advanced Osteoarthritis of the Knee and Proximal Tibiofibular Joint With Compressive Peroneal Neuropathy: 3-Year Follow-Up On a Complex Case. 61
33385040 2020
4
Internal Neurolysis of the Common Peroneal Nerve With Lower Extremity Flexion Increases Likelihood for Direct End-End Nerve Repairs. 61
33062478 2020
5
Peroneal neuropathy caused by an extraneural ganglion cyst in the supracondylar area of the femur: A case report. 61
32925762 2020
6
Discussion: Identifying Common Peroneal Neuropathy before Foot Drop. 61
32842116 2020
7
Identifying Common Peroneal Neuropathy before Foot Drop. 61
32459730 2020
8
Transient pelvic limb neuropathy following proximal metatarsal and tarsal magnetic resonance imaging in seven horses. 61
31498918 2020
9
Subclinical Peroneal Neuropathy Affects Ambulatory, Community-Dwelling Adults and Is Associated with Falling. 61
32221217 2020
10
Ultrasound-guided treatment of common peroneal neuropathy caused by Baker's cyst: a clinical note - A case report. 61
33329814 2020
11
Peroneal neuropathy and bariatric surgery: untying the knot. 61
31735096 2020
12
Role of a wireless surface electromyography in dystonic gait in functional movement disorders: A case report. 61
32047779 2020
13
Peroneal Nerve Palsy due to Bulky Osteochondroma from the Fibular Head: A Rare Case and Literature Review. 61
33274093 2020
14
Bifocal Tibial Kaposiform Hemangioendothelioma Responsive to Vincristine Therapy: A Case Report. 61
31866667 2019
15
Compressive peroneal neuropathy by an intraneural ganglion cyst combined with L5 radiculopathy: A case report. 61
31689879 2019
16
Nerve entrapments related to muscle herniation. 61
31325324 2019
17
Acute bilateral drop foot as a complication of prolonged squatting due to haemorrhoid. 61
31625702 2019
18
High Prevalence of Asymptomatic Anterior Tarsal Tunnel Syndrome in Toddy Tappers of South India: A Case Series of 21 Participants. 61
31602156 2019
19
Outcome of complex tibial plateau fractures with Ilizarov external fixation with or without minimal internal fixation. 61
31072699 2019
20
An 11-year analysis of peripheral nerve injuries in high school sports. 61
30392428 2019
21
Long-term outcomes in a 25-year-old female affected with lipin-1 deficiency. 61
31240148 2019
22
Peroneal nerve decompression: institutional review and meta-analysis to identify prognostic associations with favorable and unfavorable surgical outcomes. 61
30738397 2019
23
Diagnostic value of ultrasonography in peroneal neuropathy 61
30541235 2018
24
MRI of Foot Drop: How We Do It. 61
30152741 2018
25
Mononeuropathy due to Entrapment of Dorsal Cutaneous Peroneal Nerve: Clinical, Electrophysiological, and Imaging Findings. 61
30510862 2018
26
Causes of peroneal neuropathy associated with orthopaedic leg lengthening in different canine models. 61
29802558 2018
27
Anatomical Variants of "Short Head of Biceps Femoris Muscle" Associated with Common Peroneal Neuropathy in Korean Populations : An MRI Based Study. 61
29991110 2018
28
Immediate Nerve Transfer for Treatment of Peroneal Nerve Palsy Secondary to an Intraneural Ganglion: Case Report and Review. 61
29845044 2018
29
Delayed compression of the common peroneal nerve following rotational lateral gastrocnemius flap: case report. 61
28753118 2018
30
Surgical Results of Common Peroneal Nerve Neuroplasty at Lateral Fibular Neck. 61
29355794 2018
31
Late Peroneal Neuropathy after Open Surgical Treatment of Popliteal Artery Aneurysm. 61
28947218 2018
32
Ultrasound Evaluation and Surgical Excision of a Fabella Causing Peroneal Neuropathy in a Track Athlete. 61
30693123 2018
33
Preventive Effect of Nutrition Support on Peroneal Neuropathy in Cancer Patients. 61
30671437 2018
34
Peroneal nerve decompression. 61
29291292 2018
35
Foot drop caused by a movable cystic mass during knee motion. 61
29562484 2018
36
Bilateral peroneal neuropathy after bariatric surgery: A case report. 61
31453478 2017
37
Explaining peroneal neuropathy after ankle sprain. 61
28456862 2017
38
Seiza-induced neuropathy: an occupational peroneal neuropathy in a Japanese lady. 61
28409244 2017
39
Common Peroneal Neuropathy With Anterior Tibial Artery Occlusion: A Case Report. 61
28971059 2017
40
Recognition of peroneal intraneural ganglia in an historical cohort with "negative" MRIs. 61
28258311 2017
41
Electrophysiologic features of fibular neuropathy in childhood and adolescence. 61
27615598 2017
42
The nearly invisible intraneural cyst: a new and emerging part of the spectrum. 61
28245669 2017
43
Immediate Nerve Transfer for the Treatment of Peroneal Nerve Palsy Secondary to an Intraneural Ganglion: Case Report and Review. 61
29026813 2017
44
Ankle-Foot Orthosis Made by 3D Printing Technique and Automated Design Software. 61
28827977 2017
45
Median and common peroneal neuropathy in coir workers of Alappuzha district, Kerala. 61
28298838 2017
46
Peroneal neuropathy in giant cell arteritis. 61
28028163 2017
47
Subclinical Peroneal Neuropathy: A Common, Unrecognized, and Preventable Finding Associated With a Recent History of Falling in Hospitalized Patients. 61
28376439 2016
48
A Proximally Based Sural Fasciocutaneous Flap for the Treatment of Recurrent Peroneal Neuropathy: A Case Report. 61
27536494 2016
49
Vascular Complications After Total Knee Arthroplasty-A Single Institutional Experience. 61
26869061 2016
50
Role of Sonography in the Diagnosis and Treatment of Common Peroneal Neuropathy Secondary to Fabellae. 61
26782165 2016

Variations for Peroneal Neuropathy

Expression for Peroneal Neuropathy

Search GEO for disease gene expression data for Peroneal Neuropathy.

Pathways for Peroneal Neuropathy

Pathways related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.41 LPIN3 LPIN2 LPIN1
2
Show member pathways
12.34 LPIN3 LPIN2 LPIN1
3
Show member pathways
12.2 LPIN3 LPIN2 LPIN1
4
Show member pathways
12.01 LPIN3 LPIN2 LPIN1
5
Show member pathways
11.95 LPIN3 LPIN2 LPIN1
6 11.45 LPIN3 LPIN2 LPIN1
7 10.92 LPIN3 LPIN2 LPIN1
8
Show member pathways
10.62 LPIN2 LPIN1
9 10.25 LPIN3 LPIN2 LPIN1

GO Terms for Peroneal Neuropathy

Biological processes related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.8 SCX LPIN3 LPIN2 LPIN1 LITAF
2 lipid metabolic process GO:0006629 9.65 LPIN3 LPIN2 LPIN1
3 fatty acid metabolic process GO:0006631 9.63 LPIN3 LPIN2 LPIN1
4 dephosphorylation GO:0016311 9.61 LPIN3 LPIN2 LPIN1
5 cellular response to insulin stimulus GO:0032869 9.54 LPIN3 LPIN2 LPIN1
6 phosphatidylcholine biosynthetic process GO:0006656 9.5 LPIN3 LPIN2 LPIN1
7 cellular lipid metabolic process GO:0044255 9.43 LPIN3 LPIN2 LPIN1
8 triglyceride biosynthetic process GO:0019432 9.33 LPIN3 LPIN2 LPIN1
9 fatty acid catabolic process GO:0009062 9.13 LPIN3 LPIN2 LPIN1
10 phosphatidylethanolamine biosynthetic process GO:0006646 8.8 LPIN3 LPIN2 LPIN1

Molecular functions related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription coactivator activity GO:0003713 9.13 LPIN3 LPIN2 LPIN1
2 phosphatidate phosphatase activity GO:0008195 8.8 LPIN3 LPIN2 LPIN1

Sources for Peroneal Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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