MCID: PRN016
MIFTS: 33

Peroneal Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Peroneal Neuropathy

MalaCards integrated aliases for Peroneal Neuropathy:

Name: Peroneal Neuropathy 12 15
Peroneal Neuropathies 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4201
MeSH 45 D020427
NCIt 51 C27596
UMLS 74 C0747533

Summaries for Peroneal Neuropathy

MalaCards based summary : Peroneal Neuropathy, also known as peroneal neuropathies, is related to neuropathy and foot drop. An important gene associated with Peroneal Neuropathy is LITAF (Lipopolysaccharide Induced TNF Factor), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic cell lineage. The drug Complement System Proteins has been mentioned in the context of this disorder. Affiliated tissues include bone, testes and skin.

Related Diseases for Peroneal Neuropathy

Diseases related to Peroneal Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 neuropathy 10.9
2 foot drop 10.1
3 peroneal nerve, accessory deep 10.0
4 radiculopathy 10.0
5 orbital plasma cell granuloma 10.0 MME TNFRSF1B
6 chronic orbital inflammation 10.0 MME TNFRSF1B
7 angioedema 10.0 CPN1 MME
8 varicose veins 9.9
9 leprosy 3 9.9
10 crohn's disease 9.9
11 endocarditis 9.9
12 tetanus 9.9
13 mononeuropathy 9.9
14 pigmented villonodular synovitis 9.9
15 synovitis 9.9
16 anterior compartment syndrome 9.9
17 paraplegia 9.9
18 compartment syndrome 9.9
19 villonodular synovitis 9.9
20 hansen's disease 9.9
21 trichuriasis 9.9 MME TNF
22 spermatocele 9.9 MME TNF
23 skin sarcoidosis 9.9 TNF TNFRSF1B
24 juvenile ankylosing spondylitis 9.8 TNF TNFRSF1B
25 spondylitis 9.8 TNF TNFRSF1B
26 chronic gonococcal salpingitis 9.8 TNF TNFRSF1B
27 complex regional pain syndrome 9.8 MME TNF
28 granulomatous dermatitis 9.8 TNF TNFRSF1B
29 scleral disease 9.8 TNF TNFRSF1B
30 pustulosis of palm and sole 9.8 TNF TNFRSF1B
31 periodic fever, familial, autosomal dominant 9.8 TNF TNFRSF1B
32 post-transplant lymphoproliferative disease 9.8 TNF TNFRSF1B
33 chronic salpingitis 9.8 TNF TNFRSF1B
34 panuveitis 9.8 TNF TNFRSF1B
35 cogan syndrome 9.8 TNF TNFRSF1B
36 melkersson-rosenthal syndrome 9.8 TNF TNFRSF1B
37 hypersensitivity reaction type iv disease 9.8 TNF TNFRSF1B
38 palindromic rheumatism 9.8 TNF TNFRSF1B
39 leukocyte disease 9.8 MME TNF
40 exanthem 9.8 TNF TNFRSF1B
41 uveal disease 9.8 TNF TNFRSF1B
42 guillain-barre syndrome 9.8 TNF TNFRSF1B
43 spondyloarthropathy 1 9.8 TNF TNFRSF1B
44 primary bacterial infectious disease 9.7 TNF TNFRSF1B
45 bone inflammation disease 9.7 TNF TNFRSF1B
46 membranous nephropathy 9.7 MME TNF
47 peripheral nervous system disease 9.7 LITAF TNF
48 juvenile rheumatoid arthritis 9.7 TNF TNFRSF1B
49 sarcoidosis 1 9.6 TNF TNFRSF1B
50 acute salpingitis 9.6 MME TNF TNFRSF1B

Graphical network of the top 20 diseases related to Peroneal Neuropathy:



Diseases related to Peroneal Neuropathy

Symptoms & Phenotypes for Peroneal Neuropathy

Drugs & Therapeutics for Peroneal Neuropathy

Drugs for Peroneal Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins Not Applicable

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Evaluation of the Safety and Performance of the NESS L300 Plus System Completed NCT01237860 Phase 3
2 Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis Completed NCT00872053 Phase 1, Phase 2
3 Sensory Potentials and Ultrasonography in Common Peroneal Mononeuropathy Completed NCT03753178
4 Effect of FES Interventions on Gait Dynamics in Stroke Population Completed NCT01952613 Not Applicable
5 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822
6 Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke Completed NCT02199795 Not Applicable
7 Treating Foot Drop in People With Multiple Sclerosis Using Electrical Stimulation Completed NCT02123537 Not Applicable
8 Walking With FES or AFO in People With MS With Foot Drop Completed NCT01977287
9 Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot Drop Completed NCT01914016 Not Applicable
10 Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop Completed NCT01138995 Not Applicable
11 High-resolution Ultrasound in Lower Extremity Nerves and Common Fibular Neuropathies. Recruiting NCT03560505
12 Functional Electrical Stimulation During Walking in Cerebral Palsy Recruiting NCT03440632 Not Applicable
13 Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke. Recruiting NCT02693834 Not Applicable
14 Ankle Robot to Reduce Foot Drop in Stroke Active, not recruiting NCT02483676 Not Applicable
15 Multi-pad FES System for Drop Foot Treatment Not yet recruiting NCT02729636 Not Applicable
16 Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03556709 Not Applicable
17 Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project Not yet recruiting NCT03530592 Not Applicable
18 The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop Terminated NCT01001390 Not Applicable
19 Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee Arthroplasty Withdrawn NCT02856958 Not Applicable

Search NIH Clinical Center for Peroneal Neuropathy

Cochrane evidence based reviews: peroneal neuropathies

Genetic Tests for Peroneal Neuropathy

Anatomical Context for Peroneal Neuropathy

MalaCards organs/tissues related to Peroneal Neuropathy:

42
Bone, Testes, Skin

Publications for Peroneal Neuropathy

Articles related to Peroneal Neuropathy:

(show top 50) (show all 87)
# Title Authors Year
1
Diagnostic value of ultrasonography in peroneal neuropathy ( 30541235 )
2018
2
Preventive Effect of Nutrition Support on Peroneal Neuropathy in Cancer Patients. ( 30671437 )
2018
3
Ultrasound Evaluation and Surgical Excision of a Fabella Causing Peroneal Neuropathy in a Track Athlete. ( 30693123 )
2018
4
Anatomical Variants of "Short Head of Biceps Femoris Muscle" Associated with Common Peroneal Neuropathy in Korean Populations : An MRI Based Study. ( 29991110 )
2018
5
Causes of peroneal neuropathy associated with orthopaedic leg lengthening in different canine models. ( 29802558 )
2018
6
Late Peroneal Neuropathy after Open Surgical Treatment of Popliteal Artery Aneurysm. ( 28947218 )
2018
7
Common Peroneal Neuropathy With Anterior Tibial Artery Occlusion: A Case Report. ( 28971059 )
2017
8
Explaining peroneal neuropathy after ankle sprain. ( 28456862 )
2017
9
Median and common peroneal neuropathy in coir workers of Alappuzha district, Kerala. ( 28298838 )
2017
10
Seiza-induced neuropathy: an occupational peroneal neuropathy in a Japanese lady. ( 28409244 )
2017
11
Peroneal neuropathy in giant cell arteritis. ( 28028163 )
2017
12
Subclinical Peroneal Neuropathy: A Common, Unrecognized, and Preventable Finding Associated With a Recent History of Falling in Hospitalized Patients. ( 28376439 )
2016
13
Foot and Ankle Kinematics and Dynamic Electromyography: Quantitative Analysis of Recovery From Peroneal Neuropathy in a Professional Football Player. ( 27791976 )
2016
14
Role of Sonography in the Diagnosis and Treatment of Common Peroneal Neuropathy Secondary to Fabellae. ( 26782165 )
2016
15
A Proximally Based Sural Fasciocutaneous Flap for the Treatment of Recurrent Peroneal Neuropathy: A Case Report. ( 27536494 )
2016
16
Sonographic evaluation of common peroneal neuropathy in patients with foot drop. ( 25792587 )
2015
17
Isolated superficial peroneal neuropathy: a rare presentation of Hansen's disease (leprosy). ( 24939189 )
2015
18
Delayed onset of peroneal neuropathy after minor ankle torsion in a 9-year-old boy. ( 23435281 )
2014
19
Early detection of peroneal neuropathy by ultrasound. ( 24600072 )
2014
20
Ganglion cyst at the fibular head causing common peroneal neuropathy diagnosed with ultrasound and electrodiagnostic examination: a case report. ( 24919081 )
2014
21
An unusual cause of peroneal neuropathy. ( 25149929 )
2014
22
Editorial comment: An unusual cause of peroneal neuropathy. ( 25149930 )
2014
23
Association between the use of gel pads under patients' knees and the incidence of peroneal neuropathy following liver transplantation. ( 25189305 )
2014
24
[Magnetic resonance neurography in peroneal neuropathy related to sclerotherapy of varicose veins]. ( 25347902 )
2014
25
Assessment of hip abductor power in patients with foot drop: a simple and useful test to differentiate lumbar radiculopathy and peroneal neuropathy. ( 22805342 )
2013
26
Fibular (peroneal) neuropathy: electrodiagnostic features and clinical correlates. ( 23177035 )
2013
27
Peroneal neuropathy misdiagnosed as L5 radiculopathy: a case report. ( 23618508 )
2013
28
High-resolution 3-T MR neurography of peroneal neuropathy. ( 21416383 )
2012
29
Atypical presentations of common peroneal neuropathy. ( 22732160 )
2012
30
Common peroneal neuropathy and cancer. ( 22805690 )
2012
31
Common fibular (peroneal) neuropathy as the result of a ganglion cyst. ( 23202278 )
2012
32
Common peroneal neuropathy related to cryotherapy and compression in a footballer. ( 21253977 )
2011
33
Peroneal neuropathy after weight loss: a high-resolution ultrasonographic characterization of the common peroneal nerve. ( 21534018 )
2011
34
Acute common peroneal neuropathy due to hand positioning in normal labor and delivery. ( 21768840 )
2011
35
Peroneal neuropathy after tibio-fibular fracture. ( 22506187 )
2011
36
Compression-caused peroneal neuropathy: commentary from a biopsychologist. ( 19996836 )
2010
37
Compression peroneal neuropathy following a bicycle injury in a child. ( 20357722 )
2010
38
An unusual presentation of peroneal neuropathy secondary to pigmented villonodular synovitis: a case report. ( 19205665 )
2009
39
Atypical deep peroneal neuropathy in the setting of an accessory deep peroneal nerve. ( 19609929 )
2009
40
Peroneal neuropathy following liver transplantation: possible predisposing factors and outcome. ( 20353377 )
2009
41
Compound nerve action potential of common peroneal nerve and sural nerve action potential in common peroneal neuropathy. ( 18303210 )
2008
42
Peroneal neuropathy after liver transplantation. ( 18929798 )
2008
43
Evaluation and treatment of peroneal neuropathy. ( 19468889 )
2008
44
Bilateral foot drop after intestinal surgery: peroneal neuropathy unabated in elderly patients. ( 17979916 )
2007
45
Adolescence peroneal neuropathy associated with rapid marked weight reduction: case report and literature review. ( 17166754 )
2007
46
Peroneal neuropathy due to ground pad burn injury after a radiofrequency ablation surgery. ( 17206480 )
2007
47
Drop foot in Crohn's disease: reported nadir incidence of peroneal neuropathy. ( 17663426 )
2007
48
Ganglion: an uncommon cause of compressive peroneal neuropathy. ( 18040131 )
2007
49
High-resolution ultrasound as a diagnostic adjunct in common peroneal neuropathy. ( 18071050 )
2007
50
Common peroneal neuropathy in patients after first-time stroke. ( 18210927 )
2007

Variations for Peroneal Neuropathy

Expression for Peroneal Neuropathy

Search GEO for disease gene expression data for Peroneal Neuropathy.

Pathways for Peroneal Neuropathy

GO Terms for Peroneal Neuropathy

Biological processes related to Peroneal Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-mediated signaling pathway GO:0033209 9.4 TNF TNFRSF1B
2 response to glucocorticoid GO:0051384 9.37 CPN1 TNF
3 cellular response to lipopolysaccharide GO:0071222 9.33 LITAF TNF TNFRSF1B
4 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.32 TNF TNFRSF1B
5 extrinsic apoptotic signaling pathway GO:0097191 9.26 TNF TNFRSF1B
6 positive regulation of membrane protein ectodomain proteolysis GO:0051044 8.96 TNF TNFRSF1B
7 peptide metabolic process GO:0006518 8.62 CPN1 MME

Sources for Peroneal Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....