Drugs for Persistent Fetal Circulation Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 48)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Adenosine |
Approved, Investigational |
Phase 4 |
|
58-61-7 |
60961 |
Synonyms:
(2R,3R,4R,5R)-2-(6-AMINOPURIN-9-YL)-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL
(2R,3R,4R,5R)-2-(6-AMINOPURIN-9-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL
(2R,3R,4R,5R)-2-(6-AMINOPURIN-9-YL)-5-METHYLOL-TETRAHYDROFURAN-3,4-DIOL
(2R,3R,4S,5R)-2-(6-AMINO-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL
(2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
1-(6-Amino-9H-purin-9-yl)-1-deoxy-beta-delta-ribofuranose
1-(6-Amino-9H-purin-9-yl)-1-deoxy-beta-D-ribofuranose
6-Amino-9-b-D-ribofuranosyl-9H-purine
6-Amino-9beta-delta-ribofuranosyl-9H-purine
6-Amino-9beta-D-ribofuranosyl-9H-purine
6-Amino-9-beta-D-ribofuranosyl-9H-purine
6-Amino-9-β-D-ribofuranosyl-9H-purine
9-b-D-Ribofuranosidoadenine
9-b-D-Ribofuranosyl-9H-purin-6-amine
9-beta-D-Arabinofuranosyladenine
9-beta-delta-Arabinofuranosyladenine
9-beta-delta-Ribofuranosidoadenine
9beta-delta-Ribofuranosyl-9H-purin-6-amine
9-beta-delta-Ribofuranosyl-9H-purin-6-amine
9beta-delta-Ribofuranosyladenine
9-beta-delta-Ribofuranosyladenine
9-beta-D-Ribofuranosidoadenine
9beta-D-Ribofuranosyl-9H-purin-6-amine
9-beta-D-Ribofuranosyl-9H-purin-6-amine
9beta-D-Ribofuranosyladenine
9-beta-D-Ribofuranosyladenine
9-Î’-D-ribofuranosidoadenine
9-Î’-D-ribofuranosyl-9H-purin-6-amine
ADENIN RIBOSIDE
Adenine deoxyribonucleoside
|
Adenine nucleoside
Adenine riboside
Adenine-9beta-delta-ribofuranoside
Adenine-9beta-D-ribofuranoside
Adenocard
Adenocard®|Adenoscan®
Adenocor
ADENOGESIC
Adenoscan
Adenosin
ADENOSINA
ADENOSINE
ADÉNOSINE
ADENOSINUM
Adenyldeoxyriboside
Ade-rib
Ado
b-D-Adenosine
beta-Adenosine
beta-D-Adenosine
beta-delta-Adenosine
Boniton
Deoxyadenosine
Desoxyadenosine
Myocol
NSC-7652
Nucleocardyl
Sandesin
SR-96225
Î’-D-adenosine
|
|
2 |
|
Pharmaceutical Solutions |
|
Phase 4 |
|
|
|
3 |
|
Benzocaine |
Approved, Investigational |
Phase 3 |
|
1994-09-7, 94-09-7 |
2337 |
Synonyms:
(P-(Ethoxycarbonyl)phenylamine
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-Aminobenzoate
4-Aminobenzoate ethyl ester
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Carbethoxyaniline
Acetate, benzocaine
Aethoform
AEZODENT
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthin
Anestezin
Anesthesin
Anesthesine
Anesthone
ANTHISAN PLUS
AR01
AR-01
Baby anbesol
Bensokain
Benzoak
Benzocaina
BENZOCAINE
Benzocaine acetate
Benzocaine formate
Benzocaine hydrobromide
Benzocaine hydrochloride
Benzocaine methanesulfonate
Benzocainum
BURNEZE
CHILDREN'S CHLORASEPTIC
DEQUACAINE
Dermoplast
Diet ayds
Ethoform
Ethyl 4-aminobenzoate
|
Ethyl 4-aminobenzoic acid
Ethyl aminobenzoate
Ethyl aminobenzoic acid
Ethyl P-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethyl p-aminophenylcarboxylic acid
Ethylester kyseliny P-aminobenzoove
Formate, benzocaine
Hurricaine
Hydrobromide, benzocaine
Hydrochloride, benzocaine
Identhesin
Keloform
LANACANE
MEDILAVE
Methanesulfonate, benzocaine
NESTOSYL
Norcain
Norcaine
NSC-41531
NSC-4688
Orabase-b
Ora-jel
ORAJEL
Orthesin
p-(Ethoxycarbonyl)aniline
P-Aminobenzoate
P-Aminobenzoic acid
P-Aminobenzoic acid ethyl ester
Parathesin
Parathesine
p-Carbethoxyaniline
p-Ethoxycarboxylic aniline
Slim mint gum
Solarcaine
Solu H
Topcaine
TYROSOLVEN
TYROZETS
|
|
4 |
|
Tannic acid |
Approved |
Phase 3 |
|
1401-55-4 |
16129878 16129778 |
Synonyms:
Acid, tannic
ácido tánico
Acids, tannic
E181
FEMA NO. 3042
Gallotannic acid
|
Gallotannin
NSC-656273
TANNIC ACID
Tannic acids
Tannins
|
|
5 |
|
Sodium citrate |
Approved, Investigational |
Phase 3 |
|
68-04-2 |
23431961 |
Synonyms:
Anhydrous sodium citrate
Anhydrous trisodium citrate
Citric acid, trisodium salt
Natrii citras
Natrocitral
Sodium citrate anhydrous
Sodium citrate, anhydrous
|
Sodium citrate,anhydrous
Sodium citric acid
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
trisodium citrate anhydrous
Trisodium citrate, anhydrous
Trisodium-citrate
|
|
6 |
|
Sildenafil |
Approved, Investigational |
Phase 3 |
|
139755-83-2, 171599-83-0 |
5212 135398744 |
Synonyms:
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulphonyl)-4-methylpiperazine
1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
1-{[3-(4,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)-4-ETHOXYPHENYL]SULFONYL}-4-METHYLPIPERAZINE
5-[2-ETHOXY-5-(4-METHYLPIPERAZIN-1-YLSULFONYL)PHENYL]-1-METHYL-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDIN-7(6H)-ONE
5-[2-ETHOXY-5-(4-METHYL-PIPERAZINE-1-SULFONYL)-PHENYL]-1-METHYL-3-PROPYL-1,6-DIHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE
Acetildenafil
Aphrodil
Caverta
Citrate, sildenafil
Desmethyl sildenafil
Desmethylsildenafil
HIP0908
HIP-0908
Homosildenafil
Hydroxyhomosildenafil
Lactate, sildenafil
NCX 911
|
NCX-911
NIPATRA
Nitrate, sildenafil
Revatio
Sildenafil
Sildenafil citrate
Sildenafil lactate
Sildenafil nitrate
Sildenafil Viagra
Sildenafil, desmethyl
Sildenafilo
UK-92480
UK-9248010
UK-92480-10
Viagra
Viagra®
VIZARSIN
|
|
7 |
|
Racephedrine |
Approved, Experimental |
Phase 2, Phase 3 |
|
299-42-3, 90-82-4, 90-81-3 |
5032 9294 7028 |
Synonyms:
(-)-Ephedrine
(+) Threo-2-(methylamino)-1-phenyl-1-propanol
(+)-(1S,2S)-Pseudoephedrine
(+-)-Ephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-Threo-ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-Pseudoephedrine
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
Acunaso
Besan
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-ephedrine
Efedrina
Emerphed® (ephedrine sulfate injection)
Ephedrine
Ephedrine DL-form
Ephedrine erythro isomer
Ephedrine hydrochloride
Ephedrine renaudin
Ephedrine sulfate
Ephedrine threo isomer
Erythro isomer OF ephedrine
Hydrochloride, ephedrine
Isoephedrine
L(-)-Ephedrine
L(−)-EPHEDRINE
|
L-(+)-Pseudoephedrine
L(+)-Psi-ephedrine
L-Ephedrine
L-Erythro-2-(methylamino)-1-phenylpropan-1-ol
Neodurasina
Novafed
NSC-170951
NSC-8971
Pseudoefedrina
Pseudoephedrine
pseudoéphédrine
Pseudoephedrine D-form
Pseudoephedrine ephedrine
Pseudoephedrine HCL
Pseudoephedrine hydrochloride
Pseudoephedrinum
PSEUDOPHEDRINE SULPHATE
Psi-ephedrin
Psi-ephedrine
Racephedrine
Renaudin brand OF ephedrine hydrochloride
Renaudin, ephedrine
Sal phedrine
Sal-phedrine
SalPhedrine
SINUTAB
Sudafed
Sulfate, ephedrine
Threo isomer OF ephedrine
trans-Ephedrine
Wendt brand OF ephedrine sulfate
ψ-ephedrine
|
|
8 |
|
Phenylephrine |
Approved |
Phase 2, Phase 3 |
|
59-42-7 |
6041 |
Synonyms:
(-)-m-Hydroxy-a-(methylaminomethyl)benzyl alcohol
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol
(−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol
(-)-m-Hydroxy-α-(methylaminomethyl)benzyl alcohol
(R)-3-[-1-HYDROXY-2-(METHYLAMINO)ETHYL]PHENOL
(R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
AB-101 (PHENYLEPHRINE)
Adrianol
Ak-dilate
Ak-nefrin
Alcon efrin
Alconefrin nasal drops 12
Alconefrin nasal drops 25
Alconefrin nasal drops 50
Alconefrin nasal spray 25
BENZENEMETHANOL, 3-HYDROXY-.ALPHA.-[(METHYLAMINO)METHYL]-, (R)-
BENZENEMETHANOL, 3-HYDROXY-ALPHA-((METHYLAMINO)METHYL)-, (R)-
BENZYL ALCOHOL, M-HYDROXY-ALPHA-((METHYLAMINO)METHYL)-, (-)-
Biomydrin
CYCLOMYDRIL
Dilatair
Dimetane
Dionephrine
Doktors
DUO-MEDIHALER
Duration
Fenilefrina
Fenilefrina [INN-Spanish]
I-phrine
Isophrim
Isophrin
Isopto frin
J8.601K
L-(3-Hydroxyphenyl)-N-methylethanolamine
L-Phenylephedrine
L-Phenylephrine
Mesaton
Mesatone
Mesatonum
Metaoxedrin
Metaoxedrine
Metaoxedrinum
Metasympatol
Metasynephrine
|
Metsatonum
Mezaton
Minims phenylephrine
m-Methylaminoethanolphenol
m-Oxedrine
m-oxedrine|metasynephrine
m-Sympathol
m-Sympatol
m-Synephrine
Mydfrin
Neo synephrine
Neofrin
Neophryn
Neosynephrine
Neo-synephrine
Neo-synephrine nasal drops
Neo-synephrine nasal jelly
Neo-synephrine nasal spray
Neo-synephrine pediatric nasal drops
Nostril
Nostril spray pump
Nostril spray pump mild
Ocugestrin
Ocu-phrin sterile eye drops
Ocu-phrin sterile ophthalmic solution
PEF100
Phenoptic
PHENYLEPHRINE
Phenylephrine hydrochloride
Phenylephrine minims
Phenylephrine tannate
Phenylephrinum
Phenylephrinum [INN-Latin]
Prefrin
Prefrin liquifilm
Pyracort D
R(-)-Mezaton
R(-)-Phenylephrine
Relief eye drops for red eyes
Rhinall
Spersaphrine
Tannate, phenylephrine
Vicks sinex
Visadron
|
|
9 |
|
Oxymetazoline |
Approved, Investigational |
Phase 2, Phase 3 |
|
1491-59-4 |
4636 |
Synonyms:
2-(4-Tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-Tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
Afrin
Afrin®|oxymethazoline|SCH-9384|Upneeq® (opthalmic solution)|Vicks Sinex®
Hydrochloride, oxymetazoline
OCUCLEAR
Operil
Oximetazolinum
|
Oxymetazolina
OXYMETAZOLINE
Oxymétazoline
Oxymetazoline hydrochloride
Oxymetazoline hydrochloride crystalline
Oxymetazolinum
Oxymethazoline
Oxymetozoline
SCH-9384
VICKS SINEX
|
|
10 |
|
Bosentan |
Approved, Investigational |
Phase 3 |
|
147536-97-8 |
104865 |
Synonyms:
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulphornamide
4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
BOSENTAN
BOSENTÁN
Bosentan anhydrous
Bosentan hydrate
Bosentan monohydrate
|
Bosentanum
p-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulphonamide
RO 47-0203
RO 47-0203|Tracleer®
RO-470203029
RO-47-0203-029
Tracleer
|
|
11 |
|
Citric acid |
Approved, Nutraceutical, Vet_approved |
Phase 3 |
|
77-92-9 |
311 |
Synonyms:
2-hydroxy-1,2,3-propanetricarboxyic acid
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylate
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Acid monohydrate, citric
ácido cítrico
Acidum citricum
Aciletten
Anhydrous citrate
Anhydrous citric acid
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
Chemfill
Citraclean
Citrate
Citrate anhydrous
Citretten
CITRIC ACID
Citric acid anhydrous
CITRIC ACID HYDRATE
Citric acid monoglyceride
|
Citric acid monohydrate
Citric acid, anhydrous
Citric acid,anhydrous
Citro
Citronensaeure
Citronensäure
e 330
e330
E-330
FEMA NO. 2306
H3Cit
Hydrocerol a
INS NO.330
INS-330
Kyselina citronova
Monohydrate, citric acid
NSC-112226
NSC-30279
NSC-626579
Suby g
Uralyt u
UROLOGIC G
Uro-trainer
|
|
12 |
|
Cardiotonic Agents |
|
Phase 2, Phase 3 |
|
|
|
13 |
|
Phosphodiesterase Inhibitors |
|
Phase 3 |
|
|
|
14 |
|
Phosphodiesterase 5 Inhibitors |
|
Phase 3 |
|
|
|
15 |
|
Citrate |
|
Phase 3 |
|
|
|
16 |
|
Central Nervous System Stimulants |
|
Phase 2, Phase 3 |
|
|
|
17 |
|
Adrenergic alpha-Agonists |
|
Phase 2, Phase 3 |
|
|
|
18 |
|
Adrenergic Agonists |
|
Phase 2, Phase 3 |
|
|
|
19 |
|
Adrenergic Agents |
|
Phase 2, Phase 3 |
|
|
|
20 |
|
Vasoconstrictor Agents |
|
Phase 2, Phase 3 |
|
|
|
21 |
|
Mydriatics |
|
Phase 2, Phase 3 |
|
|
|
22 |
|
Sympathomimetics |
|
Phase 2, Phase 3 |
|
|
|
23 |
|
Nasal Decongestants |
|
Phase 2, Phase 3 |
|
|
|
24 |
|
Antihypertensive Agents |
|
Phase 3 |
|
|
|
25 |
|
Endothelin Receptor Antagonists |
|
Phase 3 |
|
|
|
26 |
|
Magnesium sulfate |
Approved, Investigational, Vet_approved |
Phase 1, Phase 2 |
|
7487-88-9 |
|
Synonyms:
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulphate
|
magnesium(II) sulfate
Magnesiumsulfat
MgSO4
|
|
27 |
|
Epoprostenol |
Approved |
Phase 2 |
|
61849-14-7, 35121-78-9 |
5282411 |
Synonyms:
(5Z,13E)-(15S)-6,9a-Epoxy-11a,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9a-Epoxy-11a,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9-alpha-Epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9-alpha-Epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9Α-epoxy-11α,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9Α-epoxy-11α,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E,15S)-6,9a-Epoxy-11a,15-dihydroxyprosta-5,13-dienoate
(5Z,13E,15S)-6,9a-Epoxy-11a,15-dihydroxyprosta-5,13-dienoic acid
(5Z,9a,11a,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oate
(5Z,9a,11a,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oic acid
(5Z,9alpha,11alpha,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oate
(5Z,9alpha,11alpha,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oic acid
(5Z,9Α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oate
(5Z,9Α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-Oic acid
ACT-385781A
Epoprostanol
|
Epoprostenol
EPOPROSTENOL SODIUM
Epoprostenol sodium salt, (5Z,9alpha,11alpha,13E,15S)-isomer
EPOPROSTENOLSODIUM
FLOLAN
PGI2
PG-I2
PGX
Prostacyclin
PROSTACYCLIN SODIUM SALT
prostacyclin|prostacyclin I2|prostaglandin I2|vasocyclin
Prostacycline
Prostaglandin I(2)
PROSTAGLANDIN I2
Prostaglandin X
U-53217
U-53217A
Vasocyclin
VELETRI
|
|
28 |
|
Treprostinil |
Approved, Investigational |
Phase 2 |
|
81846-19-7 |
6918140 |
Synonyms:
((1R,2R,3AS,9as)-2-hydroxy-1-((3S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cylopent(b)naphthalen-5-yl)oxy)acetate
(1R,2R,3AS,9AS)-[[2,3,3A,4,9,9A-HEXAHYDRO-2-HYDROXY- 1-[(3S)-3-HYDROXYOCTYL]-1H-BENZ[F]INDEN-5-YL] OXY]ACETIC ACID
[[(1R,2R,3AS,9AS)-2-HYDROXY-1-[(3S)-3-HYDROXYOCTYL]-2,3,3A,4,9,9A-HEXAHYDRO-1H-CYCLOPENTA[B]NAPHTALEN-5-YL]OXY]ACETIC ACID
15AU81
15-AU-81
LRX-15
LRX-15|Remodulin®|Tyvaso®
Orenitram
Remodulin
Trepostinil sodium
Treprostinil
Tréprostinil
|
Treprostinil diethanolamine
Treprostinil diolamin
Treprostinil diolamine
Treprostinil sodium
Treprostinilo
Treprostinilum
TRESPROSTINIL
TYVASO
UNIPROST
UT-15
UT-15C
|
|
29 |
|
Tezosentan |
Investigational |
Phase 2 |
|
180384-57-0 |
|
Synonyms:
5-Isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1H-tetrazol-5-yl--pyridin-4-yl)--pyrimidin-4-ylamide
ACT-050089
RO-610612
|
RO-61-0612
TEZOSENTAN
Veletri
|
|
30 |
|
Hormones |
|
Phase 1, Phase 2 |
|
|
|
31 |
|
Anti-Arrhythmia Agents |
|
Phase 1, Phase 2 |
|
|
|
32 |
|
Calcium, Dietary |
|
Phase 1, Phase 2 |
|
|
|
33 |
|
Anticonvulsants |
|
Phase 1, Phase 2 |
|
|
|
34 |
|
Anesthetics |
|
Phase 1, Phase 2 |
|
|
|
35 |
|
calcium channel blockers |
|
Phase 1, Phase 2 |
|
|
|
36 |
|
Analgesics |
|
Phase 1, Phase 2 |
|
|
|
37 |
|
Tocolytic Agents |
|
Phase 1, Phase 2 |
|
|
|
38 |
|
Antidepressive Agents, Tricyclic |
|
Phase 2 |
|
|
|
39 |
|
Calcium |
Nutraceutical |
Phase 1, Phase 2 |
|
7440-70-2 |
271 |
Synonyms:
Ca
Ca(2+)
Ca2+
Calcio
CALCIUM
Calcium element
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CALCIUM ion
Calcium(2+)
Calcium, doubly charged positive ion
Calcium, elemental
Elemental calcium
Kalzium
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40 |
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Metaraminol |
Approved, Investigational |
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54-49-9 |
5906 |
Synonyms:
(-)-Erythro-metaraminol
1-(m-Hydroxyphenyl)-2-amino-1-propanol
1-Metaraminol
2-Amino-1-(m-hydroxyphenyl)-1-propanol
3-Hydroxyphenylisopropanolamine
a-(1-Aminoethyl)-3-hydroxybenzenemethanol
a-(m-Hydroxyphenyl)-b-aminopropanol
alpha-(1-Aminoethyl)-3-hydroxybenzenemethanol
alpha-(m-Hydroxyphenyl)-beta-aminopropanol
Aramine
Araminol
Bitartrate, metaraminol
Hydroxynorephedrine
Hydroxyphenylpropanolamine
Isophenylephrine
L-Metaraminol
m Hydroxynorephedrine
m Hydroxyphenylpropanolamine
Merck brand OF metaraminol bitartrate
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Merck sharp and dohme brand OF metaraminol bitartrate
Meta hydroxynorephedrine
Meta-hydroxynorephedrine
Metaradrin
METARADRINE
METARAMINOL
MÉTARAMINOL
Metaraminol bitartrate
Metaraminol bitartrate (1:1)
Metaraminol tartrate
Metaraminolum
m-Hydroxy norephedrine
m-Hydroxynorephedrine
m-Hydroxyphenylpropanolamine
m-Hydroxypropadrine
Tartrate, metaraminol
Α-(1-aminoethyl)-3-hydroxybenzenemethanol
Α-(m-hydroxyphenyl)-β-aminopropanol
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41 |
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Carbon monoxide |
Approved, Investigational |
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630-08-0 |
281 |
Synonyms:
[CO]
C#O
Carbon monoxide
carbon(II) oxide
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Carboneum oxygenisatum
CO
Monoxide, carbon
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42 |
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Tadalafil |
Approved, Investigational |
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171596-29-5 |
110635 |
Synonyms:
(6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
351, IC
6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Adcirca
Adcirca®|Cialis®|IC-351|IC351
Cialis
|
IC351
IC-351
ICOS 351
Tadalafil
Tadalafilo
Tadanafil
Zalutia
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43 |
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Milrinone |
Approved |
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78415-72-2 |
4197 |
Synonyms:
1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile
Corotrop
Corotrope
Lactate, milrinone
Milrila
Milrinona
Milrinone
Milrinone lactate
milrinone lactate|Primacor®
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Milrinonum
Primacor
Sanofi brand OF milrinone lactate
Sanofi synthelabo brand OF milrinone
Sanofi synthelabo brand OF milrinone lactate
Sanofi winthrop brand OF milrinone lactate
WIN-472032
WIN-47203-2
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44 |
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Immunoglobulins |
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45 |
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Antibodies |
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46 |
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Liver Extracts |
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47 |
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Phosphodiesterase 3 Inhibitors |
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48 |
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Natriuretic Peptide, Brain |
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Interventional clinical trials:
(show all 34)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Inhaled Nitric Oxide in Neonates With Elevated A-aDO2 Gradients Not Requiring Mechanical Ventilation |
Completed |
NCT00732537 |
Phase 4 |
inhaled Nitric Oxide;Oxygen (>90% by hood) - standard therapy |
2 |
Oral Sildenafil in Persistent Pulmonary Hypertension of Neonates Secondary to Meconium Aspiration Syndrome: A Randomized Placebo Controlled Trial |
Completed |
NCT01757782 |
Phase 4 |
Oral Sildenafil;Placebo (distilled water) |
3 |
Effect of Early iNO on Oxidative Stress, Vascular Tone and Inflammation in Term and Late-Preterm Infants With Hypoxic Respiratory Failure |
Withdrawn |
NCT01891500 |
Phase 4 |
Inhaled nitric oxide;Nitrogen Gas;Crossover iNO |
4 |
Early Combined Use of Inhaled Nitric Oxide and Oral Sildenafil on the Outcome of Pulmonary Hypertension in New Born Infants |
Unknown status |
NCT01558466 |
Phase 3 |
Sildenafil;diluent |
5 |
A MULTI-CENTRE, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, TWO-ARMED, PARALLEL GROUP STUDY TO EVALUATE EFFICACY AND SAFETY OF IV SILDENAFIL IN THE TREATMENT OF NEONATES WITH PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN (PPHN) OR HYPOXIC RESPIRATORY FAILURE AND AT RISK FOR PPHN, WITH A LONG TERM FOLLOW-UP INVESTIGATION OF DEVELOPMENTAL PROGRESS 12 AND 24 MONTHS AFTER COMPLETION OF STUDY TREATMENT |
Completed |
NCT01720524 |
Phase 3 |
placebo;iv sildenafil |
6 |
Ephedrine Versus Phenylephrine Infusion for Prevention of Spinal Hypotension During Cesarean Section: Effect on Maternal Cardiodynamics and Fetal Circulation: Randomized Double-blind Study |
Completed |
NCT03047109 |
Phase 2, Phase 3 |
Phenylephrine;Ephedrine |
7 |
The Randomized Inhaled Nitric Oxide Study (NINOS) in Full-Term and Nearly Full-Term Infants With Hypoxic Respiratory Failure |
Terminated |
NCT00005776 |
Phase 3 |
Inhaled nitric oxide;Placebo |
8 |
Early Inhaled Nitric Oxide Therapy in Term and Near Term Infants With Respiratory Failure |
Terminated |
NCT00005773 |
Phase 3 |
Inhaled Nitric Oxide;Standard iNO therapy |
9 |
Multicenter, Double-blind, Placebo-controlled, Randomized, Prospective Study of Bosentan as Adjunctive Therapy to Inhaled Nitric Oxide in the Management of Persistent Pulmonary Hypertension of the Newborn (PPHN) |
Terminated |
NCT01389856 |
Phase 3 |
Bosentan;Matching placebo |
10 |
Nebulized Magnesium Sulfate for Treatment of Persistent Pulmonary Hypertension of The Newborn |
Completed |
NCT04328636 |
Phase 1, Phase 2 |
Nebulized Magnesium Sulfate;Intravenous Magnesium Sulfate |
11 |
Milrinone in Congenital Diaphragmatic Hernia |
Recruiting |
NCT02951130 |
Phase 2 |
Milrinone;Placebo (5% Dextrose) |
12 |
Intravenous Remodulin (Treprostinil) as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn: A Randomized, Placebo-Controlled, Safety and Efficacy Study |
Recruiting |
NCT02261883 |
Phase 2 |
IV Remodulin;Placebo |
13 |
Effectiveness of Nebulized Magnesium Sulfate Combined With Sildenafil Citrate in Persistent Pulmonary Hypertension of Newborn |
Recruiting |
NCT04898114 |
Phase 1, Phase 2 |
Magnesium sulfate;Sildenafil Citrate |
14 |
A Single Arm Single Centre Study To Investigate Safety And Efficacy Of Sildenafil In Near Term And Term Newborns With Persistent Pulmonary Hypertension Of The Newborn (PPHN) |
Terminated |
NCT01069861 |
Phase 2 |
sildanefil |
15 |
A Randomized, Double Blind, Placebo-controlled Pilot Study of the Safety and Effective Dosing of Inhaled Iloprost in Pediatric Patients With Pulmonary Hypertension Treated With Inhaled Nitric Oxide |
Withdrawn |
NCT00981591 |
Phase 1, Phase 2 |
Iloprost;Placebo |
16 |
An Open Label Single Arm, Single Centre Study to Investigate the Safety and Efficacy of IV Sildenafil in Neonates With Persistent Pulmonary Hypertension of the Newborn (PPHN) |
Withdrawn |
NCT01360671 |
Phase 2 |
Sildenafil |
17 |
Pharmacokinetics of Sildenafil in Premature Infants |
Completed |
NCT01670136 |
Phase 1 |
1 dose of sildenafil |
18 |
Doppler Ultrasonographic Assessment of Fetal Internal Thoracic Artery Indexes |
Unknown status |
NCT04686240 |
|
|
19 |
Examination of Perfusion Index in Term and Preterm Newborns Through Plethismography |
Unknown status |
NCT02380040 |
|
|
20 |
Compare of Continued Nitro Oxide Inhalation and Nitro Oxide Inhalation Continued With Oral Sildenafil on Treatment of Neonatal Persistent Pulmonary Hypertension |
Unknown status |
NCT01373749 |
|
NO inhalation;NO inhalation continued with sildenafil |
21 |
Ephedrine, Phenylephrine and Metaraminol Effects on Maternal Cardiac Output, Uterine Blood Flow and Fetal Circulation in Patients With Preeclampsia Under Spinal Anesthesia for Cesarean |
Unknown status |
NCT02245191 |
|
Ephedrine;Phenylephrine;Metaraminol |
22 |
NO Need to Ventilate: A Trial of Non-invasive iNO in Persistent Pulmonary Hypertension of the Newborn |
Completed |
NCT00139217 |
|
iNO |
23 |
Risk Factors for Pulmonary Hypertension of the Newborn |
Completed |
NCT00005497 |
|
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24 |
NEURodevelopmental Outcome in Children Between One and Five Years After Persistent Pulmonary Hypertension Of the Newborn |
Completed |
NCT04841070 |
|
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25 |
Antibody Secreting Cell (ASC) and Immunoactive Protein Profiles in Neonates on Extracorporeal Membrane Oxygenation (ECMO) |
Completed |
NCT00371241 |
|
|
26 |
Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children |
Completed |
NCT00005323 |
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|
27 |
Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study |
Completed |
NCT01203423 |
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28 |
A Feasibility Study to Consider the Relationship Between Markers of Red Cell Damage, Inflammation and the Recovery Process of Newborns Requiring Extracorporeal Membrane Oxygenation (ECMO) for Persistent Pulmonary Hypertension of the Newborn (PPHN): Mi-ECMO |
Completed |
NCT02940327 |
|
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29 |
Prostaglandin G/H Synthase-1 (PTGS1) Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn (PPHN) |
Recruiting |
NCT00710177 |
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30 |
Assessment of Effects of Maternal Smoking on Fetal Liver Circulation With Ultrasonography |
Active, not recruiting |
NCT04721782 |
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31 |
Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension (POST-IT) |
Enrolling by invitation |
NCT04938167 |
|
|
32 |
Population Pharmacokinetics and Dosage Individualization of Bosentan, Sildenafil and Tadalafil in Persistent Pulmonary Hypertension of the Newborn |
Not yet recruiting |
NCT04379180 |
|
Bosentan Tablets;Sildenafil Tablet;Tadalafil Tablets |
33 |
Clinical Significance of N-Terminal Pro-Brain Natriuretic Peptide Levels in Persistent Pulmonary Hypertension |
Terminated |
NCT00443859 |
|
|
34 |
Milrinone Pharmacokinetics and Pharmacodynamics in Newborns With Persistent Pulmonary Hypertension of the Newborn - a Pilot Study to Enable a Randomized Trial of Intervention |
Terminated |
NCT01088997 |
|
Milrinone Lactate |
Inferred drug relations via
UMLS
71
/
NDF-RT
50
:
Tolazoline
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Tolazoline Hydrochloride
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