PGAD
MCID: PRS119
MIFTS: 15

Persistent Genital Arousal Disorder (PGAD)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Persistent Genital Arousal Disorder

MalaCards integrated aliases for Persistent Genital Arousal Disorder:

Name: Persistent Genital Arousal Disorder 54
Persistent Genital Arousal 54
Pgad 54

Classifications:



Summaries for Persistent Genital Arousal Disorder

NIH Rare Diseases : 54 Persistent genital arousal disorder (PGAD) in men may be considered as the condition of priapism and unwanted ejaculatory fluids being released without any sexual interest. In women there is still no consensus about a formal definition, but some of the experts propose that in women it should be defined as a rare, unwanted, and intrusive sexual dysfunction associated with excessive and unremitting genital arousal and engorgement in the absence of sexual interest. The persistent genital arousal usually does not resolve with orgasm and causes personal distress. Features include excessive excitement or excessive genital (lubrication, swelling, and engorgement) or other somatic responses. Causes may be neurological (central or peripheral involving the pudendal nerve), related to medication, vascular, hormonal, psychological or others.  Diagnosis of the cause is essential for an adequate patient management. The treatment may include avoiding offending medications, using medications that stabilize nerve transmission and/or effect mood, local topical anesthetic agents, ice and hormonal replacement. More recently PGAD has being described as one component of a broader Restless Genital Syndrome if the PGAD was also associated with urinary frequency/urgency and restless leg syndrome.

MalaCards based summary : Persistent Genital Arousal Disorder, also known as persistent genital arousal, is related to sexual disorder and premature ejaculation. An important gene associated with Persistent Genital Arousal Disorder is OXT (Oxytocin/Neurophysin I Prepropeptide).

Wikipedia : 77 Persistent genital arousal disorder (PGAD), previously called persistent sexual arousal syndrome, is... more...

Related Diseases for Persistent Genital Arousal Disorder

Diseases related to Persistent Genital Arousal Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 sexual disorder 10.0
2 premature ejaculation 10.0
3 priapism 10.0
4 tarlov cysts 10.0
5 depression 10.0
6 taylor's syndrome 10.0

Graphical network of the top 20 diseases related to Persistent Genital Arousal Disorder:



Diseases related to Persistent Genital Arousal Disorder

Symptoms & Phenotypes for Persistent Genital Arousal Disorder

Drugs & Therapeutics for Persistent Genital Arousal Disorder

Search Clinical Trials , NIH Clinical Center for Persistent Genital Arousal Disorder

Genetic Tests for Persistent Genital Arousal Disorder

Anatomical Context for Persistent Genital Arousal Disorder

Publications for Persistent Genital Arousal Disorder

Articles related to Persistent Genital Arousal Disorder:

(show top 50) (show all 58)
# Title Authors Year
1
Can pharmacotherapy help persistent genital arousal disorder? ( 30220233 )
2018
2
Genital Sensations in Persistent Genital Arousal Disorder: A Case for an Overarching Nosology of Genitopelvic Dysesthesias? ( 30301706 )
2018
3
Case Report: Persistent Genital Arousal Disorder in an Adolescent Woman. ( 30513343 )
2018
4
Symptom Characteristics and Medical History of an Online Sample of Women Who Experience Symptoms of Persistent Genital Arousal. ( 28459348 )
2018
5
An Online Cross-Sectional Comparison of Women With Symptoms of Persistent Genital Arousal, Painful Persistent Genital Arousal, and Chronic Vulvar Pain. ( 29609914 )
2018
6
Persistent genital arousal disorder - a case report. ( 28455899 )
2017
7
Diagnosis and Treatment of Persistent Genital Arousal Disorder. ( 29472831 )
2017
8
Clomipramine trial for treatment-resistant persistent genital arousal disorder: a case series. ( 28635538 )
2017
9
Persistent Genital Arousal Disorder-Fact or Fiction? ( 28262102 )
2017
10
Pudendal Neuromodulation as a Treatment for Persistent Genital Arousal Disorder-A Case Series. ( 28657994 )
2017
11
Lamotrigine-induced persistent genital arousal disorder: An unusual side effect. ( 28139448 )
2017
12
Treatment of a female patient with persistent genital arousal and Parkinson's disease with paliperidone. ( 27422565 )
2017
13
Sacral Neuromodulation for the Treatment of Persistent Genital Arousal Disorder. ( 27399995 )
2016
14
Persistent Genital Arousal Disorder. ( 27570347 )
2016
15
Persistent Genital Arousal Disorder-Case Report of Symptomatic Relief of Symptoms With Transcranial Magnetic Stimulation. ( 26796498 )
2016
16
Persistent Genital Arousal Disorder: A Review of Its Conceptualizations, Potential Origins, Impact, and Treatment. ( 27461894 )
2016
17
Case Reports of a Mother and Daughter Diagnosed With Persistent Genital Arousal Disorder. ( 27599029 )
2016
18
Persistent Genital Arousal Disorder Caused by Spinal Meningeal Cysts in the Sacrum: Successful Neurosurgical Treatment. ( 26348167 )
2015
19
Persistent genital arousal disorder: Successful treatment with leuprolide (antiandrogen). ( 26600597 )
2015
20
A Case of Comorbid Persistent Genital Arousal Disorder and Premature Ejaculation: Killing Two Birds With One Stone. ( 26035619 )
2015
21
First reported case of isolated persistent genital arousal disorder in a male. ( 25767735 )
2015
22
Penile Priapism, Clitoral Priapism, and Persistent Genital Arousal Disorder: A Contemporary Review. ( 27784607 )
2015
23
Persistent genital arousal disorder following selective serotonin reuptake inhibitor cessation. ( 25928703 )
2015
24
Psychological factors predicting the distress to female persistent genital arousal symptoms. ( 24328817 )
2015
25
Persistent genital arousal disorder: confluent patient history of agitated depression, paroxetine cessation, and a tarlov cyst. ( 25525548 )
2014
26
Hypnotherapy for persistent genital arousal disorder: a case study. ( 24568327 )
2014
27
A periclitoral mass as a cause of persistent genital arousal disorder. ( 23577645 )
2014
28
A new medical treatment with botulinum toxin in persistent genital arousal disorder: successful treatment of two cases. ( 24168013 )
2014
29
Persistent genital arousal in women with pelvic and genital pain. ( 24798670 )
2014
30
Persistent genital arousal in women with pelvic and genital pain. ( 25222353 )
2014
31
Persistent genital arousal disorder: a clinical challenge. ( 23697448 )
2013
32
Cognitive and emotional determinants characterizing women with persistent genital arousal disorder. ( 23534888 )
2013
33
Persistent genital arousal disorder-update on the monster sexual dysfunction. ( 24112351 )
2013
34
A case of persistent genital arousal disorder successfully treated with topiramate in a physically healthy individual. ( 23945446 )
2013
35
Persistent genital arousal disorder: characterization, etiology, and management. ( 23157369 )
2013
36
Persistent genital arousal and restless genitalia: sexual dysfunction or subtype of vulvodynia? ( 23970620 )
2013
37
Persistent genital arousal disorder misdiagnosed because of Islamic religious bathing rituals: a report of three cases. ( 22900625 )
2012
38
Prevalence of sacral spinal (Tarlov) cysts in persistent genital arousal disorder. ( 22594432 )
2012
39
Persistent genital arousal disorder: successful treatment with duloxetine and pregabalin in two cases. ( 22024021 )
2012
40
Physical therapy treatment of persistent genital arousal disorder during pregnancy: a case report. ( 20059652 )
2010
41
Persistent genital arousal disorder associated with functional hyperconnectivity of an epileptic focus. ( 20144694 )
2010
42
Persistent genital arousal disorder: a review of the literature and recommendations for management. ( 20498115 )
2010
43
Persistent genital arousal disorder (PGAD): case report of long-term symptomatic management with electroconvulsive therapy. ( 19686432 )
2009
44
Persistent genital arousal disorder and trazodone. Morphometric and vascular modifications of the clitoris. A case report. ( 19674253 )
2009
45
Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement. ( 19228278 )
2009
46
Persistent genital arousal disorder in 18 Dutch women: Part I. MRI, EEG, and transvaginal ultrasonography investigations. ( 19138359 )
2009
47
Words of wisdom. Re: Persistent genital arousal disorder in women: case reports of association with anti-depressant usage and withdrawal. ( 19645091 )
2009
48
Persistent genital arousal disorder: a review of the literature and recommendations for management. ( 19451319 )
2009
49
FSFI scores of women with persistent genital arousal disorder compared with published scores of women with female sexual arousal disorder and healthy controls. ( 19040625 )
2009
50
Persistent genital arousal disorder in 18 Dutch women: Part II. A syndrome clustered with restless legs and overactive bladder. ( 19138358 )
2009

Variations for Persistent Genital Arousal Disorder

Expression for Persistent Genital Arousal Disorder

Search GEO for disease gene expression data for Persistent Genital Arousal Disorder.

Pathways for Persistent Genital Arousal Disorder

GO Terms for Persistent Genital Arousal Disorder

Sources for Persistent Genital Arousal Disorder

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