MCID: PRS119
MIFTS: 14

Persistent Genital Arousal Disorder

Categories: Rare diseases

Aliases & Classifications for Persistent Genital Arousal Disorder

MalaCards integrated aliases for Persistent Genital Arousal Disorder:

Name: Persistent Genital Arousal Disorder 53
Persistent Genital Arousal 53
Pgad 53

Classifications:



Summaries for Persistent Genital Arousal Disorder

NIH Rare Diseases : 53 Persistent genital arousal disorder (PGAD) in men may be considered as the condition of priapism and unwanted ejaculatory fluids being released without any sexual interest. In women there is still no consensus about a formal definition, but some of the experts propose that in women it should be defined as a rare, unwanted, and intrusive sexual dysfunction associated with excessive and unremitting genital arousal and engorgement in the absence of sexual interest. The persistent genital arousal usually does not resolve with orgasm and causes personal distress. Features include excessive excitement or excessive genital (lubrication, swelling, and engorgement) or other somatic responses. Causes may be neurological (central or peripheral involving the pudendal nerve), related to medication, vascular, hormonal, psychological or others.  Diagnosis of the cause is essential for an adequate patient management. The treatment may include avoiding offending medications, using medications that stabilize nerve transmission and/or effect mood, local topical anesthetic agents, ice and hormonal replacement. More recently PGAD has being described as one component of a broader Restless Genital Syndrome if the PGAD was also associated with urinary frequency/urgency and restless leg syndrome.

MalaCards based summary : Persistent Genital Arousal Disorder, also known as persistent genital arousal, is related to tarlov cysts and depression. An important gene associated with Persistent Genital Arousal Disorder is OXT (Oxytocin/Neurophysin I Prepropeptide).

Wikipedia : 76 Persistent genital arousal disorder (PGAD), previously called persistent sexual arousal syndrome, is... more...

Related Diseases for Persistent Genital Arousal Disorder

Diseases related to Persistent Genital Arousal Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 tarlov cysts 10.1
2 depression 10.1
3 premature ejaculation 9.9
4 priapism 9.9
5 meningitis 9.9

Graphical network of the top 20 diseases related to Persistent Genital Arousal Disorder:



Diseases related to Persistent Genital Arousal Disorder

Symptoms & Phenotypes for Persistent Genital Arousal Disorder

Drugs & Therapeutics for Persistent Genital Arousal Disorder

Search Clinical Trials , NIH Clinical Center for Persistent Genital Arousal Disorder

Genetic Tests for Persistent Genital Arousal Disorder

Anatomical Context for Persistent Genital Arousal Disorder

Publications for Persistent Genital Arousal Disorder

Articles related to Persistent Genital Arousal Disorder:

(show all 38)
# Title Authors Year
1
Persistent genital arousal disorder - a case report. ( 28455899 )
2017
2
Diagnosis and Treatment of Persistent Genital Arousal Disorder. ( 29472831 )
2017
3
Clomipramine trial for treatment-resistant persistent genital arousal disorder: a case series. ( 28635538 )
2017
4
Persistent Genital Arousal Disorder-Fact or Fiction? ( 28262102 )
2017
5
Pudendal Neuromodulation as a Treatment for Persistent Genital Arousal Disorder-A Case Series. ( 28657994 )
2017
6
Lamotrigine-induced persistent genital arousal disorder: An unusual side effect. ( 28139448 )
2017
7
Sacral Neuromodulation for the Treatment of Persistent Genital Arousal Disorder. ( 27399995 )
2016
8
Persistent Genital Arousal Disorder. ( 27570347 )
2016
9
Persistent Genital Arousal Disorder-Case Report of Symptomatic Relief of Symptoms With Transcranial Magnetic Stimulation. ( 26796498 )
2016
10
Persistent Genital Arousal Disorder: A Review of Its Conceptualizations, Potential Origins, Impact, and Treatment. ( 27461894 )
2016
11
Case Reports of a Mother and Daughter Diagnosed With Persistent Genital Arousal Disorder. ( 27599029 )
2016
12
Persistent Genital Arousal Disorder Caused by Spinal Meningeal Cysts in the Sacrum: Successful Neurosurgical Treatment. ( 26348167 )
2015
13
Persistent genital arousal disorder: Successful treatment with leuprolide (antiandrogen). ( 26600597 )
2015
14
A Case of Comorbid Persistent Genital Arousal Disorder and Premature Ejaculation: Killing Two Birds With One Stone. ( 26035619 )
2015
15
First reported case of isolated persistent genital arousal disorder in a male. ( 25767735 )
2015
16
Penile Priapism, Clitoral Priapism, and Persistent Genital Arousal Disorder: A Contemporary Review. ( 27784607 )
2015
17
Persistent genital arousal disorder following selective serotonin reuptake inhibitor cessation. ( 25928703 )
2015
18
Persistent genital arousal disorder: confluent patient history of agitated depression, paroxetine cessation, and a tarlov cyst. ( 25525548 )
2014
19
Hypnotherapy for persistent genital arousal disorder: a case study. ( 24568327 )
2014
20
A periclitoral mass as a cause of persistent genital arousal disorder. ( 23577645 )
2014
21
A new medical treatment with botulinum toxin in persistent genital arousal disorder: successful treatment of two cases. ( 24168013 )
2014
22
Persistent genital arousal disorder: a clinical challenge. ( 23697448 )
2013
23
Cognitive and emotional determinants characterizing women with persistent genital arousal disorder. ( 23534888 )
2013
24
Persistent genital arousal disorder-update on the monster sexual dysfunction. ( 24112351 )
2013
25
A case of persistent genital arousal disorder successfully treated with topiramate in a physically healthy individual. ( 23945446 )
2013
26
Persistent genital arousal disorder: characterization, etiology, and management. ( 23157369 )
2013
27
Persistent genital arousal disorder misdiagnosed because of Islamic religious bathing rituals: a report of three cases. ( 22900625 )
2012
28
Prevalence of sacral spinal (Tarlov) cysts in persistent genital arousal disorder. ( 22594432 )
2012
29
Persistent genital arousal disorder: successful treatment with duloxetine and pregabalin in two cases. ( 22024021 )
2012
30
Physical therapy treatment of persistent genital arousal disorder during pregnancy: a case report. ( 20059652 )
2010
31
Persistent genital arousal disorder associated with functional hyperconnectivity of an epileptic focus. ( 20144694 )
2010
32
Persistent genital arousal disorder: a review of the literature and recommendations for management. ( 20498115 )
2010
33
Persistent genital arousal disorder (PGAD): case report of long-term symptomatic management with electroconvulsive therapy. ( 19686432 )
2009
34
Persistent genital arousal disorder and trazodone. Morphometric and vascular modifications of the clitoris. A case report. ( 19674253 )
2009
35
Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement. ( 19228278 )
2009
36
Persistent genital arousal disorder in 18 Dutch women: Part I. MRI, EEG, and transvaginal ultrasonography investigations. ( 19138359 )
2009
37
Words of wisdom. Re: Persistent genital arousal disorder in women: case reports of association with anti-depressant usage and withdrawal. ( 19645091 )
2009
38
Persistent genital arousal disorder: a review of the literature and recommendations for management. ( 19451319 )
2009

Variations for Persistent Genital Arousal Disorder

Expression for Persistent Genital Arousal Disorder

Search GEO for disease gene expression data for Persistent Genital Arousal Disorder.

Pathways for Persistent Genital Arousal Disorder

GO Terms for Persistent Genital Arousal Disorder

Sources for Persistent Genital Arousal Disorder

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