Pertussis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PRT037 MIFTS: 65	Pertussis Categories: Infectious diseases, Rare diseases, Respiratory diseases, Smell/Taste diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

Sources

Aliases & Classifications for Pertussis

MalaCards integrated aliases for Pertussis:

Name: Pertussis ¹² ⁷⁴ ⁵² ⁵⁸ ³ ¹⁵ ⁷¹

Whooping Cough ¹² ⁷⁴ ⁵² ⁵⁸ ⁴² ³ ¹⁵ ¹⁷ ³²

Bordetella Infections ⁴³ ¹⁷ ⁷¹

Whooping Cough Due to Unspecified Organism ⁷¹

Bordetella Pertussis Infection ⁵²

Bordetella Infection ¹²

Wc - Whooping Cough ¹²

Characteristics:

Orphanet epidemiological data:

⁵⁸

whooping cough
Prevalence: 1-9/100000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Respiratory diseases Smell/Taste diseases

See all MalaCards categories (disease lists)

ICD10: ³² ³³

Certain infectious and parasitic diseases

Other bacterial diseases

Whooping cough

Whooping cough due to Bordetella parapertussis

Whooping cough due to Bordetella pertussis

Whooping cough due to other Bordetella species

Whooping cough, unspecified

Orphanet: ⁵⁸

Rare infectious diseases

External Ids:

Disease Ontology ¹² DOID:1116

MeSH ⁴³ D001885

SNOMED-CT ⁶⁷ 26484003

ICD10 ³² A37 A37.0 A37.1 more

MESH via Orphanet ⁴⁴ D014917

ICD10 via Orphanet ³³ A37.0 A37.1 A37.8 more

UMLS via Orphanet ⁷² C0043167 C0043168

Orphanet ⁵⁸ ORPHA1489

EFO ¹⁷ EFO_0000650 EFO_1001275

UMLS ⁷¹ C0006015 C0043167 C0043168

Sources

Summaries for Pertussis

MedlinePlus : ⁴² Whooping cough is an infectious bacterial disease that causes uncontrollable coughing. The name comes from the noise you make when you take a breath after you cough. You may have choking spells or may cough so hard that you vomit. Anyone can get whooping cough, but it is more common in infants and children. It's especially dangerous for infants. The coughing spells can be so bad that it is hard for infants to eat, drink, or breathe. To make a diagnosis, your doctor may do a physical exam, blood tests, chest x-rays, or nose or throat cultures. Before there was a vaccine, whooping cough was one of the most common childhood diseases and a major cause of childhood deaths in the U.S. Now most cases are prevented by vaccines. If you have whooping cough, treatment with antibiotics may help if given early. Centers for Disease Control and Prevention

MalaCards based summary : Pertussis, also known as whooping cough, is related to tetanus and haemophilus influenzae, and has symptoms including fever, pruritus and snoring. An important gene associated with Pertussis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Pertussis and Signaling by GPCR. The drugs Montelukast and Iron have been mentioned in the context of this disorder. Affiliated tissues include respiratory tract, neutrophil and smooth muscle, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : ¹² A commensal bacterial infectious disease that results in inflammation located in respiratory tract, has material basis in Bordetella pertussis, or has material basis in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).

CDC : ³ Pertussis, also known as whooping cough, is a highly contagious respiratory disease. It is caused by the bacterium Bordetella pertussis. Pertussis is known for uncontrollable, violent coughing which often makes it hard to breathe. After cough fits, someone with pertussis often needs to take deep breaths, which result in a "whooping" sound. Pertussis can affect people of all ages, but can be very serious, even deadly, for babies less than a year old. The best way to protect against pertussis is by getting vaccinated

Wikipedia : ⁷⁴ Whooping cough, also known as pertussis or 100-day cough, is a highly contagious bacterial disease.... more...

Sources

Related Diseases for Pertussis

Diseases related to Pertussis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 754)

#	Related Disease	Score	Top Affiliating Genes
1	tetanus	32.5	TNF IL6 IL1B IL10
2	haemophilus influenzae	31.9	TNF CXCL8
3	cholera	31.6	TNF IL6 GNAI1 FOS CXCL8 ADCY10
4	measles	31.4	TNF TLR4 MYD88 IL6 IL1B
5	mumps	31.3	TNF IL6 IL10 CXCL8
6	allergic hypersensitivity disease	31.3	TNF TLR4 IL10 CXCL8
7	rubella	31.2	TNF TLR4 IL6 IL10 CALM1
8	pain agnosia	31.1	OPRM1 IL6 FOS
9	bronchiolitis	31.1	TNF TLR4 IL6 IL10 CXCL8
10	encephalitis	31.0	TNF IL6 IL1B IL10
11	typhoid fever	31.0	TNF TLR4 IL6 IL1B
12	chickenpox	31.0	TNF IL6 IL10
13	hepatitis a	31.0	TNF TLR4 IL10
14	neutrophil migration	31.0	MAPK1 ITGB2 ITGAM CXCL8
15	influenza	30.9	TNF MYD88 IL6 IL1B CXCL8
16	sudden infant death syndrome	30.9	TNF IL6 IL1B IL10 CXCL8
17	amebiasis	30.9	TNF TLR4 CXCL8
18	respiratory failure	30.9	TNF JUN IL6 IL1B IL10 CXCL8
19	pleurisy	30.9	TNF TLR4 CXCL8
20	post-transplant lymphoproliferative disease	30.9	TNF IL6 IL10
21	bronchopneumonia	30.9	TNF TLR4 IL6 IL10 CXCL8
22	lymphocytic choriomeningitis	30.8	MYD88 IL6 CXCL8
23	laryngitis	30.8	TNF IL6 IL1B
24	neuroblastoma	30.7	TNF OPRM1 MAPK1 JUN IL6 FOS
25	exanthem	30.7	TNF IL6 IL10 CXCL8
26	food allergy	30.7	TNF TLR4 IL10 CXCL8
27	autoimmune disease	30.7	TNF ITGAM IL6 IL1B IL10 CXCL8
28	allergic asthma	30.7	TLR4 ITGB2 ITGAM IL10 CXCL8
29	immune deficiency disease	30.7	TNF JUN ITGB2 IL6 IL10
30	bronchitis	30.7	TNF TLR4 IL6 IL1B IL10 CXCL8
31	hepatitis b	30.7	TNF TLR4 MYD88 IL6 CXCL8
32	sleep disorder	30.7	TNF IL6 FOS
33	meningoencephalitis	30.6	TNF IL6 IL10
34	autoimmune uveitis	30.6	TNF IL1B IL10
35	erythema multiforme	30.6	TNF IL6 CXCL8
36	morphine dependence	30.6	OPRM1 FOS ADCY10
37	uveitis	30.6	TNF IL6 IL10 CXCL8
38	orchitis	30.6	TNF IL6 IL10
39	thyroiditis	30.6	TNF IL6 IL10
40	chlamydia pneumonia	30.6	TNF TLR4 IL6 IL10 CXCL8
41	dermatitis	30.6	TNF TLR4 IL6 IL10 CXCL8
42	chlamydia	30.5	TNF TLR4 IL6 IL1B IL10 CXCL8
43	pneumonia	30.5	TNF TLR4 ITGAM IL6 IL1B IL10
44	human immunodeficiency virus type 1	30.5	TNF MAPK10 MAPK1 IL6 IL10
45	neuritis	30.5	TNF IL6 IL1B IL10 CXCL8
46	bacterial pneumonia	30.5	TNF TLR4 IL6 IL10 CXCL8
47	cellulitis	30.5	TNF IL6 IL10
48	otitis media	30.5	TNF TLR4 IL6 IL1B IL10 CXCL8
49	fibrosarcoma	30.5	TNF MAPK1 JUN FOS
50	pulmonary edema	30.5	TNF IL1B IL10 CXCL8

Graphical network of the top 20 diseases related to Pertussis:

Sources

Symptoms & Phenotypes for Pertussis

UMLS symptoms related to Pertussis:

fever, pruritus, snoring, coughing

GenomeRNAi Phenotypes related to Pertussis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.44	CXCL8 IL10 IL1B JUN MYD88 TNF
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.44	CXCL8 IL10 IL1B JUN MAPK1 MYD88

MGI Mouse Phenotypes related to Pertussis:

⁴⁵ (show all 14)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.36	ADCY10 FOS GNAI1 GNAZ IL10 IL1B
2	hematopoietic system	MP:0005397	10.35	FOS GNAI1 GNAZ IL10 IL1B IL6
3	cellular	MP:0005384	10.31	ADCY10 FOS IL10 IL6 ITGAM ITGB2
4	behavior/neurological	MP:0005386	10.3	FOS GNAI1 GNAZ IL10 IL6 JUN
5	cardiovascular system	MP:0005385	10.25	ADCY10 IL10 IL1B IL6 ITGB2 JUN
6	immune system	MP:0005387	10.25	FOS GNAI1 IL10 IL1B IL6 ITGAM
7	nervous system	MP:0003631	10.17	FOS GNAI1 GNAZ IL10 IL1B IL6
8	integument	MP:0010771	10.14	FOS GNAZ IL10 IL1B IL6 ITGB2
9	adipose tissue	MP:0005375	10.08	FOS GNAI1 IL6 MYD88 OPRM1 TLR4
10	neoplasm	MP:0002006	9.97	FOS IL10 IL1B IL6 MAPK1 MYD88
11	no phenotypic analysis	MP:0003012	9.86	ADCY10 GNAI1 IL10 JUN MAPK10 MYD88
12	reproductive system	MP:0005389	9.85	ADCY10 FOS GNAZ IL10 IL6 MAPK1
13	skeleton	MP:0005390	9.7	FOS GNAI1 IL10 IL1B IL6 ITGB2
14	vision/eye	MP:0005391	9.28	FOS IL10 IL6 ITGB2 JUN MAPK1

Sources

Drugs & Therapeutics for Pertussis

Drugs for Pertussis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 148)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Montelukast

Approved

Phase 4

158966-92-8

5281040

Iron

Approved, Experimental

Phase 4

7439-89-6, 15438-31-0

23925 27284

Edetic Acid

Approved, Vet_approved

Phase 4

60-00-4, 62-33-9

6049

Pentetic acid

Approved

Phase 4

67-43-6

Ceftriaxone

Approved

Phase 4

73384-59-5

5479530 5361919

Calcium

Approved, Nutraceutical

Phase 4

7440-70-2

271

BCG vaccine

Investigational

Phase 4

Leukotriene Antagonists

Phase 4

Vaccines

Phase 4

Immunologic Factors

Phase 4

Antitoxins

Phase 4

Anti-Bacterial Agents

Phase 4

Anti-Infective Agents

Phase 4

Adjuvants, Immunologic

Phase 4

Aluminum phosphate

Phase 4

Chelating Agents

Phase 4

Iron Chelating Agents

Phase 4

Anticoagulants

Phase 4

Calcium, Dietary

Phase 4

Antidotes

Phase 4

Micronutrients

Phase 4

Trace Elements

Phase 4

Nutrients

Phase 4

Heptavalent Pneumococcal Conjugate Vaccine

Phase 4

Chrysanthemum

Phase 4

Immunoglobulins

Phase 4

Antibodies

Phase 4

Deferiprone

Approved

Phase 3

30652-11-0

2972

Aluminum hydroxide

Approved, Investigational

Phase 3

21645-51-2

tannic acid

Approved

Phase 3

1401-55-4

Benzocaine

Approved, Investigational

Phase 3

1994-09-7, 94-09-7

2337

Prednisone

Approved, Vet_approved

Phase 3

53-03-2

5865

Benralizumab

Approved, Investigational

Phase 2, Phase 3

1044511-01-4

Lactitol

Investigational

Phase 3

585-86-4, 585-88-6

493591

Rho(D) Immune Globulin

Phase 3

Immunoglobulins, Intravenous

Phase 3

gamma-Globulins

Phase 3

Hemagglutinins

Phase 3

Cathartics

Phase 3

Laxatives

Phase 3

taxane

Phase 3

Somatomedin B

Phase 3

Fibrinolytic Agents

Phase 3

Pharmaceutical Solutions

Phase 3

Antibodies, Monoclonal

Phase 3

Respiratory System Agents

Phase 2, Phase 3

Anti-Asthmatic Agents

Phase 2, Phase 3

Histidine

Investigational, Nutraceutical

Phase 2, Phase 3

71-00-1

6274

Aluminum sulfate

Approved

Phase 1, Phase 2

10043-01-3

Ibuprofen

Approved

Phase 2

15687-27-1

3672

Interventional clinical trials:

(show top 50) (show all 414)

#	Name	Status	NCT ID	Phase	Drugs
1	Safety and Immunogenicity of Adult Formulation Tetanus and Diphtheria Toxoids Adsorbed Combined With Acellular Pertussis (Tdap) Vaccine Following Blood and Morrow Transplantation in Adults	Unknown status	NCT00336115	Phase 4
2	Open Label Multicentric Randomized Phase IV Post Marketing Safety, Immunogenicity and Lot-to-Lot Consistency Analysis of Shan 5 [DTPwHB-Hib (Liquid) Pentavalent Combination Vaccine] in Indian Infants	Unknown status	NCT00877357	Phase 4
3	The Efficacy and Safety of Vaccination Against Pertussis. Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis	Unknown status	NCT01301703	Phase 4
4	Comparison of Two Vaccinal Schemes for DTP-Pertussis-Hib Primo-immunisation in Very Preterm-born Neonates: a Randomised Bicentric Controlled Study	Unknown status	NCT02179996	Phase 4
5	The Influence of BCG Vaccine as a Booster TDaP-IPV Vaccination: an Explorative Study	Unknown status	NCT02771782	Phase 4
6	An Immunogenicity and Safety Study of Combined Adsorbed Tetanus, Low Dose Diphtheria and Acellular Pertussis Vaccine (Td5ap and Td1aP) Given as a School-leaving Booster to 14-15-year-old Children Primed With a Five Component Acellular Pertussis Vaccine at 3, 5 and 12 Months of Age, and a Booster Dose at 5½ Years of Age	Unknown status	NCT00870350	Phase 4
7	Clinical Study to Generate a Set of Data Characterising Clinical Events, Physiological Responses, and Innate and Adaptive Immune Responses Following a Single IM Immunisation With Boostrix® or Placebo in Healthy Adults	Unknown status	NCT02555540	Phase 4
8	A Double Blind Randomised Placebo Controlled Trial of Montelukast in the Treatment of Acute Persistent Cough in Young People and Adults in Primary Care	Unknown status	NCT01279668	Phase 4	Montelukast;Placebo
9	Safety Among Adolescents and Adults of Revaccination With Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Adacel®) 4 to 5 Years After a Previous Dose	Completed	NCT00347958	Phase 4
10	Comparison in US Adolescents of the Safety and Immunogenicity of Two Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis (Tdap) Vaccines: ADACEL™ and BOOSTRIX®	Completed	NCT00319553	Phase 4
11	A Randomised Controlled Trial Comparing Two Pertussis-containing Vaccines in Pregnancy and Vaccine Responses in UK Mothers and Their Infants	Completed	NCT02145624	Phase 4	Repevax;Boostrix-IPV
12	An Open Label Multicentric Study to Evaluate the Immunogenicity and Safety of Indigenously Developed DTPwHB-Hib (Liquid) Pentavalent Combination Vaccine (Shan 5) in Indian Infants.	Completed	NCT00617812	Phase 4
13	Immune Responses in Adults to Revaccination With Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (ADACEL®) 10 Years After a Previous Dose	Completed	NCT00712959	Phase 4
14	Regulatory Post-Marketing Surveillance (PMS) Study for ADACEL™ (Adsorbed Diphtheria, Tetanus Toxoids and Component Pertussis Combined Vaccine for Adult)	Completed	NCT01137435	Phase 4
15	Evaluation of GSK Biologicals' dTpa Booster Vaccine in Young Adults 10 Years After Previous dTpa Boosting.	Completed	NCT00610168	Phase 4
16	Safety and Immunogenicity of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (ADACEL®) in Persons ≥65 Years of Age	Completed	NCT00457249	Phase 4
17	A Single Blind, Multicentric, Comparative, Vaccine Interchangeability Trial of Shan 5 (Liquid) and Easy Five (Liquid) [Diphtheria-Tetanus- Pertussis, Hepatitis B and Hib Pentavalent Combination Vaccines] in Indian Infants.	Completed	NCT00674908	Phase 4
18	A Phase III/IV Randomised Open-label Study and Comparison of the Immunogenicity and Safety of a Single Adolescent Booster Dose of a Meningococcal Group C Conjugate-containing Booster Vaccine (Meningitec™, OR NeisVac-C™ , OR Menitorix™), When Given Concurrently With an Acellular Pertussis-containing Booster Vaccine (Repevax™ or IPV-Boostrix™)	Completed	NCT02526394	Phase 4	Pertussis containing vaccine
19	Reactogenicity of Acellular Pertussis Vaccine Booster in Adolescents Who Have Received 5 Prior Doses of BIKEN Acellular Pertussis Vaccine in Combination With Diphtheria and Tetanus Toxoids (TRIPEDIA®) or Who Have Received Primary Vaccination With 3 Doses of Whole-Cell Pertussis Vaccine, Plus at Least 1 Pertussis Booster Vaccination	Completed	NCT00304265	Phase 4
20	Vaccine Responses in Infants After Acellular Pertussis Vaccination During Pregnancy in Thailand	Completed	NCT02408926	Phase 4
21	Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand	Completed	NCT00255021	Phase 4
22	Evaluation of GSK Biological's dTpa-IPV Booster Vaccine in Children and Adolescents, 5 Years After Previous dTpa-IPV Boosting.	Completed	NCT00635128	Phase 4
23	Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents	Completed	NCT01629589	Phase 4
24	Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose	Completed	NCT01439165	Phase 4
25	Impact of Pertussis Vaccination in Pregnancy on Maternal Protection Offered to Young Infants	Completed	NCT01698346	Phase 4
26	Regulatory Post-Marketing Surveillance (PMS) Study for TETRAXIM™(Combined Vaccine of Adsorbed Diphtheria, Tetanus, Acellular Pertussis and Enhanced Inactivated Poliomyelitis)	Completed	NCT01437423	Phase 4
27	Open Clinical Study to Assess the Immune Response and Safety of a Booster Dose (5th Dose) of a Combination Vaccine Against Diphteria-Tetanus-Pertussis-Polio Given to Healthy Adolescents 15-16 Years of Age.	Completed	NCT00514059	Phase 4	Boostrix polio
28	Immunogenicity and Safety Study of a Booster Dose of GSK Biologicals' Infanrix Hexa™ (217744) in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery	Completed	NCT02853929	Phase 4
29	A Phase IV, Single-blind, Randomized, Controlled, Monocentric Study to Assess the Interchangeability of Quinvaxem (DTwP-HepB-Hib) as the 2nd and 3rd Dose After Initial Vaccination With Tritanrix HB+Hib (DTwP-HepB/Hib) With Respect to Safety and Immunogenicity in Healthy Infants at 6, 10 and 14 Weeks of Age	Completed	NCT01357720	Phase 4
30	Safety and Immunogenicity of Adacel® Vaccine Administered to Persons 10 Years of Age	Completed	NCT01311557	Phase 4
31	A Prospective, Randomized, Open-label Clinical Trial to Assess the Safety and Immunogenicity of Simultaneous vs Sequential Administration of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine and Inactivated Influenza Vaccine in Pregnant Women - Pilot	Completed	NCT02783170	Phase 4
32	Safety of the DTacP-IPV//PRP~T Combined Vaccine (PENTAXIM®) Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China	Completed	NCT01491087	Phase 4
33	Safety and Immunogenicity of DAPTACEL® (CP10/5/5/3DT Aventis Pasteur 5-component Pertussis Vaccine in Combination With Tetanus and Diphtheria Toxoids Adsorbed) Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™ (HCP20/20/5/3DT-mIPV//PRP-T)	Completed	NCT00802867	Phase 4
34	Immunogenicity and Safety of Meningococcal (Groups A, C, Y, and W-135) Diphtheria Toxoid Conjugate Vaccine (Menactra®) in Adolescents in the US When Administered Concomitantly With Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Tdap Vaccine)	Completed	NCT00777257	Phase 4
35	Immunogenicity and Safety of the Diphtheria, Tetanus, Pertussis and Inactivated Poliovirus (DPT-IPV) Vaccine Squarekids Co-administered With GSK Biologicals' Human Rotavirus (HRV) Vaccine Rotarix (GSK444563) in Healthy Infants	Completed	NCT02907216	Phase 4
36	Phase IV, Open Label Trial to Evaluate Immunogenicity of Tdap Vaccine in Post-Partum Women to Optimize Vaccination Schedule for Women Who May Have a Subsequent Child	Completed	NCT01711645	Phase 4
37	Safety & Immunogenicity of a Booster Dose of dTPa Vaccine (Boostrix®) Co-admnd. With Aventis Pasteur's Meningococcal (Serogroups A, C, Y and W-135) Polysaccharide Vaccine (Menactra™) vs Admn. of Either Vaccine Alone in Healthy Adolescents	Completed	NCT00282295	Phase 4
38	Immunogenicity and Safety Study of GSK Biologicals' Combined Diphtheria-tetanus-acellular Pertussis-hepatitis B-inactivated Polio-virus and Haemophilus Influenzae Type b Vaccine (Infanrix Hexa™) (217744) in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery	Completed	NCT02422264	Phase 4	Prevnar13
39	Immunogenicity and Safety of the Sanofi Pasteur's DTacP-IPV Combined Vaccine (TETRAXIM™) Given as a Booster Dose at 4 to 6 Years of Life in Children Previously Vaccinated With PENTAXIM™ in the Study E2I34	Completed	NCT01031303	Phase 4
40	An Immunogenicity and Safety Evaluation of Menactra® (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine) When Administered to Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age.	Completed	NCT01659996	Phase 4
41	Non-specific Effects of Vaccines - In Search of the Immunological Background	Completed	NCT00168545	Phase 4
42	A Phase IV Study to Evaluate the Primary and Booster Immune Responses of UK Infants Receiving a Licensed 6-in-1 DTaP/IPV/Hib/HBV Vaccine (Infanrix-HexaTM) With a 13-valent Pneumococcal Conjugate Vaccine and Incorporating a Randomisation Study of a Single Dose of 3 Different Meningococcal Group C Conjugate Vaccines at 3 Months of Age	Completed	NCT01896596	Phase 4
43	A Phase IV, Randomized Study to Evaluate the Immune Response of UK Infants Receiving DTaP/Hib/IPV, Meningococcal C Conjugate and Pneumococcal Conjugate Vaccines, Antibody Persistence and Responses to Booster Doses in the Second Year of Life	Completed	NCT00625677	Phase 4
44	Post-marketing, Randomized, Open-label Study to Assess the Immunogenicity and Safety of Concomitant Administration of V260 and Diphtheria, Tetanus, Pertussis and Inactivated Poliovirus Vaccine (DTP-IPV) in Japanese Healthy Infants	Completed	NCT01926015	Phase 4
45	Evaluation of GSK Biologicals' Boostrix™ Polio in Healthy Adults, 10 Years After a Booster Vaccination	Completed	NCT01323959	Phase 4
46	A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of a Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine (Tdap, Boostrix®) and Quadrivalent Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine (Gardasil®) in Healthy Adolescents When Administered With MenACWY Conjugate Vaccine	Completed	NCT01424644	Phase 4
47	Evaluation of GSK Biologicals' dTpa Booster Vaccine in Adults, Given 10 Years After Previous dTpa Boosting.	Completed	NCT00548171	Phase 4
48	An Open, Randomized, Multicenter Study of the Safety, Tolerability, and Immunogenicity of VAQTA™ Given Concomitantly With PedvaxHIB™ and Infanrix™ in Healthy Children 15 Months of Age	Completed	NCT00289913	Phase 4
49	A Phase 4, Randomized, Open-label Trial Evaluating the Safety, Tolerability, and Immunogenicity of DTaP Vaccine in Healthy Infants Given With a 7-valent Pneumococcal Conjugate Vaccine in Japan.	Completed	NCT01250756	Phase 4
50	Evaluation of GSK Biologicals' Boostrix™ in Healthy Adults, 10 Years After Previous Booster Vaccination	Completed	NCT01147900	Phase 4

Search NIH Clinical Center for Pertussis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :

ERYTHROMYCIN PWDR

Guaifenesin

Cochrane evidence based reviews: bordetella infections

Sources

Genetic Tests for Pertussis

Sources

Anatomical Context for Pertussis

The Foundational Model of Anatomy Ontology organs/tissues related to Pertussis:

¹⁹

Respiratory Tract

MalaCards organs/tissues related to Pertussis:

⁴⁰

Neutrophil, Smooth Muscle, Endothelial, Testes, T Cells, Brain, Lung

Sources

Publications for Pertussis

Articles related to Pertussis:

(show top 50) (show all 28285)

#	Title	Authors	PMID	Year
1	DTaP-IPV-HepB-Hib Vaccine (Hexyon®): An Updated Review of its Use in Primary and Booster Vaccination. ⁶¹ ⁴²	Syed YY	31444785	2019
2	Neonatal Immunity to Bordetella pertussis Infection and Current Prevention Strategies. ⁶¹ ⁴²	Argondizo-Correia C...de Brito CA	30882004	2019
3	A pilot study of a novel, incentivised mHealth technology to monitor the vaccine supply chain in rural Zambia. ⁴²	Lamanna C...Byrne L	31448013	2019
4	Coverage rates of the children vaccination programme in Greenland. ⁶¹	Albertsen N...Pedersen ML	32000619	2020
5	Protective effects of pharmacological therapies in animal models of multiple sclerosis: a review of studies 2014-2019. ⁶¹	Martinez B...Peplow PV	31960801	2020
6	Using the North Dakota IIS to Assess the Response of Health Care Providers to the ACIP Recommendation for Tdap Vaccination During Pregnancy. ⁶¹	Woinarowicz M...Howell M	31834203	2020
7	Order of Live and Inactivated Vaccines and Risk of Non-vaccine-targeted Infections in US Children 11-23 Months of Age. ⁶¹	Newcomer SR...Glanz JM	32032310	2020
8	Two centuries of immunisation in the UK (part 1). ⁶¹	Lang S...Pollard AJ	31272966	2020
9	Role of lysophosphatidic acid in vascular smooth muscle cell proliferation. ⁶¹	Liu Y...Dhalla NS	31369714	2020
10	Exploring bacterial pathogen community dynamics in freshwater beach sediments: A tale of two lakes. ⁶¹	VanMensel D...Weisener CG	31736260	2020
11	Routine Childhood Vaccines Given in the First 11 Months of Life. ⁶¹	Jacobson RM	31879133	2020
12	Safety review of tetanus toxoid, reduced diphtheria toxoid, acellular pertussis vaccines (Tdap) in adults aged ≥65 years, Vaccine Adverse Event reporting System (VAERS), United States, September 2010-December 2018. ⁶¹	Haber P...Cano M	31883809	2020
13	What Matters to Parents Regarding Immunization of Their Children: Systematic Analysis of Expert Advice to Parents in an Internet Forum. ⁶¹	Imahorn N...Heininger U	31725113	2020
14	Comparison of hepatitis B surface antibody levels induced by the pentavalent DTwP-HB-Hib versus the hexavalent DTaP-HB-Hib-IPV vaccine, administered to infants at 2, 4, 6, and 18 months of age, following monovalent hepatitis B vaccination at birth. ⁶¹	Posuwan N...Poovorawan Y	31948817	2020
15	A cost-effectiveness analysis of traditional and geographic information system-supported microplanning approaches for routine immunization program management in northern Nigeria. ⁶¹	Ali D...Dougherty L	31924428	2020
16	Expression and function of umami receptors T1R1/T1R3 in gastric smooth muscle. ⁶¹	Crowe MS...Grider JR	31721379	2020
17	Prevention of chronic diseases in middle-age women: a cross-sectional study on an Italian large sample. ⁶¹	Colombo A...Della Rosa MC	31263891	2020
18	Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001-2014. ⁶¹	Brosio F...Gabutti G	31678191	2020
19	Mandatory Vaccination in Europe. ⁶¹	Vaz OM...Omer SB	31932361	2020
20	Update from the Advisory Committee on Immunization Practices. ⁶¹	O'Leary ST...Kimberlin DW	32016424	2020
21	Beneficial role of simvastatin in experimental autoimmune myositis. ⁶¹	Maalouly G...Fares N	31863923	2020
22	π-Helix Controls Activity of Oxygen-Sensing Diguanylate Cyclases. ⁶¹	Walker JA...Weinert EE	32039439	2020
23	Childhood infectious diseases and risk of non-Hodgkin's lymphoma according to the WHO classification: A reanalysis of the Italian multicenter case-control study. ⁶¹	Parodi S...Stagnaro E	31077355	2020
24	Assessing adolescent immunization options for pertussis in Canada: A cost-utility analysis. ⁶¹	Anyiwe K...Sander B	31889607	2020
25	Dose-dependent effectiveness of acellular pertussis vaccine in infants: A population-based case-control study. ⁶¹	Mack I...Heininger U	31813648	2020
26	Timeliness and equity of infant pertussis vaccination in wales: Analysis of the three dose primary course. ⁶¹	Perry M...Cottrell S	31839466	2020
27	Structural and Functional Characterization of the Globin-Coupled Sensors of Azotobacter vinelandii and Bordetella pertussis. ⁶¹	Germani F...Dewilde S	31559835	2020
28	Vaccination during pregnancy: current and possible future recommendations. ⁶¹	Maertens K...Leuridan E	31912233	2020
29	Development of a Pertactin-Coated Beads Approach for Screening of Functional Monoclonal Antibodies. ⁶¹	He L...Azizi A	31589874	2020
30	Licensure of a Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poliovirus, Haemophilus influenzae Type b Conjugate, and Hepatitis B Vaccine, and Guidance for Use in Infants. ⁶¹	Oliver SE...Moore KL	32027629	2020
31	Hepatitis B Birth Dose Effects on Childhood Immunization in the U.S. ⁶¹	Vader DT...Evans AA	31959321	2020
32	Revisiting Role of Vaccinations in Donors, Transplant Recipients, Immunocompromised Hosts, Travelers, and Household Contacts of Stem Cell Transplant Recipients. ⁶¹	Majeed A...Anwer F	31682981	2020
33	Bacterial, viral, and fungal infection-related risk of Parkinson's disease: Meta-analysis of cohort and case-control studies. ⁶¹	Wang H...Chen L	32017453	2020
34	Coverage rates and timeliness of nationally recommended vaccinations in Swiss preschool children: A descriptive analysis using claims data. ⁶¹	Schneider R...Meier CR	31791812	2020
35	How are children who are delayed in the Childhood Vaccination Programme vaccinated: A nationwide register-based cohort study of Danish children aged 15-24 months and semi-structured interviews with vaccination providers. ⁶¹	Pedersen KB...Sorup S	30024308	2020
36	Fever After Influenza, Diphtheria-Tetanus-Acellular Pertussis, and Pneumococcal Vaccinations. ⁶¹	Walter EB...Broder KR	32029684	2020
37	Advances in Vaccines. ⁶¹	Mao HH...Chao S	31446443	2020
38	Functionally selective inhibition of the oxytocin receptor by retosiban in human myometrial smooth muscle. ⁶¹	Brighton PJ...Blanks AM	31907536	2020
39	G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody. ⁶¹	Bhudia N...Dowell SJ	31969668	2020
40	Vaccination coverage of general practitioners: a cross-sectional study from Greece. ⁶¹	Kalemaki D...Lionis C	32000009	2020
41	Role of PKCζ-NADPH oxidase signaling axis in PKCα-mediated Giα2 phosphorylation for inhibition of adenylate cyclase activity by angiotensin II in pulmonary artery smooth muscle cells. ⁶¹	Chowdhury A...Chakraborti S	31965656	2020
42	Maraviroc attenuates the pathogenesis of experimental autoimmune encephalitis. ⁶¹	Karampoor S...Keyvani H	32007705	2020
43	Current situation, causes, and countermeasures to NIP vaccine shortages in Guangzhou, China. ⁶¹	Li Z...Zhang C	31403888	2020
44	Temporally Coarse-Grained All-Atom Molecular Dynamics Achieved via Stochastic Padé Approximants. ⁶¹	Sereda YV...Ortoleva PJ	31958947	2020
45	Family Health Days program contributions in vaccination of unreached and under-immunized children during routine vaccinations in Uganda. ⁶¹	Mupere E...Aga E	31951608	2020
46	CR4056, a powerful analgesic imidazoline-2 receptor ligand, inhibits the inflammation-induced PKCε phosphorylation and membrane translocation in sensory neurons. ⁶¹	Vellani V...Giacomoni C	31454418	2020
47	Antidepressants induce profibrotic responses via the lysophosphatidic acid receptor LPA1. ⁶¹	Olianas MC...Onali P	32007501	2020
48	Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial. ⁶¹	Valea I...Agbenyega T	31951771	2020
49	Midwives' knowledge, attitudes and confidence in discussing maternal and childhood immunisation with parents: A national study. ⁶¹	Frawley JE...Hall H	31628030	2020
50	Variation in Tdap and Influenza Vaccination Coverage Among Pregnant Women by Insurance Type - Florida, 2016-2018. ⁶¹	Merritt TA...Thompson LA	31971934	2020

Sources

Genes for Pertussis

Genes related to Pertussis (0 elite genes):

(show all 36)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TLR4	Toll Like Receptor 4	Protein Coding	31.87	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
2	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	27.61	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
3	OPRM1	Opioid Receptor Mu 1	Protein Coding	27.59	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Functions Drugs & Compounds (show sections)
4	ITGB2	Integrin Subunit Beta 2	Protein Coding	27.34	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
5	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	27.26	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
6	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	27.14	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
7	GNAI1	G Protein Subunit Alpha I1	Protein Coding	24.67	GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
8	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	23.82	GeneCards inferred via : Publications Pathways & Interactions Drugs & Compounds (show sections)
9	GNA14	G Protein Subunit Alpha 14	Protein Coding	23.8	GeneCards inferred via : Publications Summaries Functions (show sections)
10	IL10	Interleukin 10	Protein Coding	21.57	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
11	TNF	Tumor Necrosis Factor	Protein Coding	21.13	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
12	IL6	Interleukin 6	Protein Coding	21.12	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
13	ADCY10	Adenylate Cyclase 10	Protein Coding	20.96	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
14	IL1B	Interleukin 1 Beta	Protein Coding	20.8	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
15	GNAZ	G Protein Subunit Alpha Z	Protein Coding	20.66	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Summaries (show sections)
16	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	20.57	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
17	ITGAM	Integrin Subunit Alpha M	Protein Coding	20.47	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
18	GNA15	G Protein Subunit Alpha 15	Protein Coding	20.08	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Functions (show sections)
19	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	20.03	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
20	CALM1	Calmodulin 1	Protein Coding	19.72	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
21	C3	Complement C3	Protein Coding	19.69	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
22	ADORA1	Adenosine A1 Receptor	Protein Coding	19.62	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
23	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	19.52	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
24	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	19.42	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
25	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	19.37	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
26	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	19.33	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
27	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	19.22	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
28	TICAM1	Toll Like Receptor Adaptor Molecule 1	Protein Coding	19.2	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
29	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	19.15	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
30	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	19.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
31	IL1A	Interleukin 1 Alpha	Protein Coding	19.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
32	TIRAP	TIR Domain Containing Adaptor Protein	Protein Coding	19.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
33	SST	Somatostatin	Protein Coding	18.99	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
34	IRF1	Interferon Regulatory Factor 1	Protein Coding	18.92	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Pathways & Interactions (show sections)
35	FPR1	Formyl Peptide Receptor 1	Protein Coding	18.86	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)
36	VIP	Vasoactive Intestinal Peptide	Protein Coding	18.8	DISEASES inferred ¹⁵ GeneCards inferred via : Publications Drugs & Compounds (show sections)

Sources

Variations for Pertussis

Sources

Expression for Pertussis

Search GEO for disease gene expression data for Pertussis.

Sources

Pathways for Pertussis

Pathways related to Pertussis according to KEGG:

³⁶

#	Name	Kegg Source Accession
1	Pertussis	hsa05133

Pathways related to Pertussis according to GeneCards Suite gene sharing:

(show top 50) (show all 210)

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by GPCR ⁶⁵ Show member pathways GPCR downstream signaling ⁶⁵ Signal Transduction ⁶⁵	14.34	TNF OPRM1 MYD88 MAPK1 JUN IL6
2	Innate Immune System ⁶⁵ Show member pathways Immune System ⁶⁵ Neutrophil degranulation ⁶⁵	14.23	TNF TLR4 OPRM1 MYD88 MAPK10 MAPK1
3	Apoptotic Pathways in Synovial Fibroblasts ⁶³ Show member pathways Actin-Based Motility by Rho Family GTPases ⁶³ Cellular Apoptosis Pathway ⁶³ DHA Signaling ⁶³ eIF2 Pathway ⁶³ ERK5 Signaling ⁶³ Glioma Invasiveness ⁶³ Mitochondrial Apoptosis ⁶³ Nuclear Receptor Activation by Vitamin-A ⁶³ p53 Mediated Apoptosis ⁶³ PPAR Pathway ⁶³ Rac1 Pathway ⁶³ Rap1 Pathway ⁶³ Telomerase Components in Cell Signaling ⁶³	14.05	TNF MAPK10 MAPK1 JUN ITGB2 ITGAM
4	ERK Signaling ⁶³ Show member pathways ILK Signaling ⁶³ MAPK Signaling ⁶³ Molecular Mechanisms of Cancer ⁶³ Rho Family GTPases ⁶³	14.01	TNF MAPK10 MAPK1 JUN ITGB2 ITGAM
5	GPCR Pathway ⁶³ Show member pathways Breast Cancer Regulation by Stathmin1 ⁶³ Estrogen Pathway ⁶³ NFAT in Immune Response ⁶³ P2Y Receptor Signaling ⁶³ Pancreatic Adenocarcinoma ⁶³ Paxillin Interactions ⁶³ Ras Pathway ⁶³	13.91	MAPK10 MAPK1 JUN ITGB2 ITGAM IL6
6	PEDF Induced Signaling ⁶³ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶³ Cytokine-cytokine receptor interaction ³⁶ Endothelin-1 Signaling Pathway ⁶³ Glucocorticoid Receptor Signaling ⁶³ IL-6 Pathway ⁶³ MIF Mediated Glucocorticoid Regulation ⁶³ MIF Regulation of Innate Immune Cells ⁶³ NFAT Signaling and Lymphocyte Interactions ⁶³ PGC1Alpha Pathway ⁶³ RAR-Gamma-RXR-Alpha Degradation ⁶³ STAT3 Pathway ⁶³	13.84	TNF TLR4 MAPK10 MAPK1 JUN IL6
7	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. ⁶⁵ Show member pathways Alzheimer disease ³⁶ Alzheimers Disease ¹ Complex I biogenesis ⁶⁵ Electron Transport Chain ¹ Formation of ATP by chemiosmotic coupling ⁶⁵ Huntington disease ³⁶ Non-alcoholic fatty liver disease (NAFLD) ³⁶ Oxidative phosphorylation ³⁶ Oxidative phosphorylation ¹ Parkinson disease ³⁶ Respiratory electron transport ⁶⁵ The citric acid (TCA) cycle and respiratory electron transport ⁶⁵ Thermogenesis ³⁶	13.75	TNF MAPK10 MAPK1 JUN IL6 IL1B
8	TGF-Beta Pathway ⁶³ Show member pathways JAK-STAT Pathway ⁶³ JNK Pathway ⁶³ MAPK Family Pathway ⁶³ Regulation of eIF4 and p70S6K ⁶³ SOCS Pathway ⁶³	13.73	TNF MAPK10 MAPK1 JUN ITGB2 ITGAM
9	Activation of cAMP-Dependent PKA ⁶³ Show member pathways Activation of PKA through GPCR ⁶³ cAMP Pathway ⁶³ PKA Signaling ⁶³	13.7	MAPK1 IL6 GNAZ GNAI1 GNA15 GNA14
10	Integrin Pathway ⁶³ Show member pathways FAK1 Signaling ⁶³ GnRH Signaling ⁶³ Inhibition of Angiogenesis by TSP1 ⁶³ Transendothelial Migration of Leukocytes ⁶³ UPA-UPAR Pathway ⁶³	13.62	MAPK10 MAPK1 JUN ITGB2 ITGAM GNAZ
11	Akt Signaling ⁶³ Show member pathways p38 Signaling ⁶³ Tec Kinases Signaling ⁶³	13.59	TNF TLR4 MYD88 MAPK10 ITGB2 ITGAM
12	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	13.57	TNF OPRM1 MYD88 MAPK1 ITGB2 ITGAM
13	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.5	TNF MAPK10 MAPK1 JUN IL6 IL1B
14	CREB Pathway ⁶³ Show member pathways Activation of PKC through GPCR ⁶³ Intracellular Calcium Signaling ⁶³ IP3 Pathway ⁶³	13.47	MAPK1 IL6 GNAZ GNAI1 GNA15 GNA14
15	Response to elevated platelet cytosolic Ca2+ ⁶⁵ Show member pathways Disinhibition of SNARE formation ⁶⁵ Hemostasis ⁶⁵ Platelet activation, signaling and aggregation ⁶⁵ Platelet degranulation ⁶⁵	13.46	MAPK1 ITGB2 ITGAM GNAI1 GNA15 GNA14
16	Nanog in Mammalian ESC Pluripotency ⁶³ Show member pathways 14-3-3 Induced Intracellular Signaling ⁶³ eNOS Signaling ⁶³ GSK3 Signaling ⁶³	13.46	TNF MAPK10 MAPK1 JUN IL6 GNAI1
17	IL-2 Pathway ⁶³ Show member pathways ErbB Family Pathway ⁶³ ErbB2-ErbB3 Heterodimers ⁶³ ErbB4 Pathway ⁶³ Growth Hormone Signaling ⁶³ HMGB1 Pathway ⁶³ IL-4 Pathway ⁶³ LPS Stimulated MAPK Signaling ⁶³ PACAP Signaling ⁶³ PI3K Signaling in B-Lymphocyte ⁶³ Prolactin Signaling ⁶³ Thrombopoietin Pathway ⁶³ TREM1 Pathway ⁶³ UVC-Induced MAPK Signaling ⁶³	13.44	TNF TLR4 MYD88 MAPK10 MAPK1 JUN
18	Phospholipase-C Pathway ⁶³ Show member pathways PTEN Pathway ⁶³	13.3	MAPK1 ITGB2 ITGAM IL6 GNAZ GNAI1
19	Sweet Taste Signaling ⁶³ Show member pathways Bitter Taste Signaling ⁶³ Cellular Effects of Sildenafil ⁶³ Melatonin Signaling ⁶³ Sperm Motility ⁶³	13.29	MAPK10 MAPK1 JUN GNAZ GNAI1 GNA15
20	Toll-like Receptor Signaling Pathway ¹ ³⁶ Show member pathways Chagas disease (American trypanosomiasis) ³⁶ Hepatitis B ³⁶ Hepatitis C ³⁶ NOD-like Receptor Signaling Pathways ⁶⁴ Regulation of toll-like receptor signaling pathway ¹	13.29	TNF TLR4 MYD88 MAPK10 MAPK1 JUN
21	DAG and IP3 signaling ⁶⁵ Show member pathways Beta-2 adrenergic-dependent CFTR expression ²² Ca-dependent events ⁶⁵ Calmodulin induced events ⁶⁵ CaM pathway ⁶⁵ Cam-PDE 1 activation ⁶⁵ CREB phosphorylation through the activation of Adenylate Cyclase ⁶⁵ Development Beta-adrenergic receptors signaling via cAMP ²² Development Role of Activin A in cell differentiation and proliferation ²² EGFR interacts with phospholipase C-gamma ⁶⁵ G Protein Signaling Pathways ¹ G-protein mediated events ⁶⁵ Inhibitory action of Lipoxin A4 on PDGF, EGF and LTD4 signaling ²² Neurophysiological process PGE2-induced pain processing ²² Opioid Signalling ⁶⁵ PKA activation ⁶⁵ PKA activation in glucagon signalling ⁶⁵ PKA-mediated phosphorylation of CREB ⁶⁵ PLC beta mediated events ⁶⁵ PLC-gamma1 signalling ⁶⁵ Signal transduction Calcium signaling ²²	13.27	OPRM1 MAPK1 GNAZ GNAI1 GNA15 GNA14
22	p70S6K Signaling ⁶³ Show member pathways mTOR Pathway ⁶³ Renin-Angiotensin Pathway ⁶³	13.26	MAPK10 MAPK1 JUN IL6 GNAI1 GNA15
23	G-Beta Gamma Signaling ⁶³ Show member pathways CRHR Pathway ⁶³ GHRH Signaling ⁶³ Hedgehog Signaling in Mammals ⁶³ Relaxin Pathway ⁶³ Signaling in Gap Junctions ⁶³	13.25	MAPK1 JUN GNAZ GNAI1 GNA15 GNA14
24	fMLP Pathway ⁶³ Show member pathways Alpha-Adrenergic Signaling ⁶³ CCR3 Pathway in Eosinophils ⁶³ CXCR4 Pathway ⁶³ Huntington's Disease Pathway ⁶³ Internalin Pathway ⁶³ Signal transduction Activation of PKC via G-Protein coupled receptor ²² VEGF and S-1P Signaling ⁶³	13.23	MAPK10 MAPK1 JUN GNAZ GNAI1 GNA15
25	TNFR1 Pathway ⁶³ Show member pathways Apoptosis and survival TNFR1 signaling pathway ²² Apoptosis through Death Receptors ⁶³ Apoptotic Pathways Triggered By HIV1 ⁶³ DR3 Signaling ⁶³ Fas Signaling ⁶³ GITR Pathway ⁶³ HIV-1 Nef- Negative effector of Fas and TNF-alpha ¹ Stimulation of the cell death response by PAK-2p34 ⁶⁵ TNF alpha Signaling Pathway ¹ TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway ¹ TNF Signaling ⁶³ TRAIL Pathway ⁶³ TWEAK Pathway ⁶³	13.19	TNF MAPK10 MAPK1 JUN IL6 GNAZ
26	Actin Nucleation by ARP-WASP Complex ⁶³ Show member pathways Actin Nucleation and Branching ⁶³ CDC42 Pathway ⁶³ RhoA Pathway ⁶³	13.19	MAPK10 JUN ITGB2 ITGAM GNAZ GNAI1
27	Human cytomegalovirus infection ³⁶ Show member pathways Human immunodeficiency virus 1 infection ³⁶ Kaposi sarcoma-associated herpesvirus infection ³⁶	13.16	TNF TLR4 MYD88 MAPK10 MAPK1 JUN
28	Sertoli-Sertoli Cell Junction Dynamics ⁶³ Show member pathways Epithelial Tight Junctions ⁶³ Germ Cell-Sertoli Cell Junction Dynamics ⁶³	13.15	TNF MAPK10 MAPK1 JUN ITGB2 ITGAM
29	CCR5 Pathway in Macrophages ⁶³ Show member pathways Androgen Signaling ⁶³ Chemokine Signaling ⁶³ Chemokine signaling pathway ³⁶	13.13	MAPK10 MAPK1 JUN GNAI1 GNA15 GNA14
30	NFAT and Cardiac Hypertrophy ⁶³ Show member pathways IGF1R Signaling ⁶³ Signaling Involved in Cardiac Hypertrophy ⁶³	13.11	MAPK10 MAPK1 JUN ITGB2 ITGAM IL6
31	Development Angiotensin activation of ERK ²² Show member pathways Cell adhesion Integrin inside-out signaling ²² Development ACM2 and ACM4 activation of ERK ²² Development Angiotensin signaling via PYK2 ²² Development EDNRB signaling ²² Development EPO-induced MAPK pathway ²² Development G-Proteins mediated regulation MARK-ERK signaling ²² Signal transduction IP3 signaling ²²	13.09	MAPK10 MAPK1 JUN ITGB2 GNAZ GNAI1
32	Pathways in cancer ³⁶	13.08	MAPK10 MAPK1 JUN IL6 GNAI1 FOS
33	Focal Adhesion ¹ ³⁶ Show member pathways HGF Pathway ⁶³ Integrin-mediated Cell Adhesion ¹	13.06	MAPK10 MAPK1 JUN ITGB2 ITGAM FOS
34	Measles ³⁶ Show member pathways Epstein-Barr virus infection ³⁶ Influenza A ³⁶	13.04	TNF TLR4 MYD88 MAPK10 MAPK1 JUN
35	Allograft rejection ¹ ³⁶ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	13.03	TNF ITGB2 IL6 IL1B IL10 CXCL8
36	Beta-Adrenergic Signaling ⁶³ Show member pathways CDK5 Pathway ⁶³ Erythropoietin Pathway ⁶³ Insulin Receptor Pathway ⁶³	13.02	MAPK10 MAPK1 JUN ITGB2 ITGAM GNAZ
37	MAPK-Erk Pathway ⁶⁶ Show member pathways Actin Dynamics Signaling Pathway ⁶⁶ G Protein-coupled Receptors Signaling ⁶⁶	13.01	MAPK1 ITGB2 ITGAM GNAI1 FOS CALM1
38	Apoptosis Modulation and Signaling ¹ Show member pathways Apoptosis ¹ Apoptosis ³⁶ Apoptosis and survival Apoptotic TNF-family pathways ²² Apoptosis Signaling Pathways ⁶⁴ Death Receptor Signaling ⁶⁶	12.99	TNF MYD88 MAPK10 MAPK1 JUN FOS
39	MAPK signaling pathway ³⁶ ¹	12.99	TNF MYD88 MAPK10 MAPK1 JUN IL1B
40	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways ⁶⁵ Show member pathways Cytosolic DNA-sensing pathway ³⁶ Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway ²² Negative regulators of RIG-I/MDA5 signaling ⁶⁵ NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 ⁶⁵ RIG-I-like Receptor Signaling ¹ RIG-I-like receptor signaling pathway ³⁶ TRAF3-dependent IRF activation pathway ⁶⁵ TRAF6 mediated IRF7 activation ⁶⁵ Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors (RLR) ⁶⁴	12.98	TNF TLR4 MYD88 MAPK10 IL6 IL1B
41	Circadian entrainment ³⁶ Show member pathways Cholinergic synapse ³⁶ Dopaminergic synapse ³⁶ Glutamatergic synapse ³⁶ Synaptic Neurotransmission Pathways: Glutamatergic Excitation ⁶⁴	12.95	MAPK10 MAPK1 GNAI1 FOS CALM1 ADCY10
42	DREAM Repression and Dynorphin Expression ⁶³ Show member pathways BMP Pathway ⁶³ Calpain Protease Regulates Cellular Mechanics ⁶³ Caspase Cascade ⁶³ Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels ⁶⁵ nNOS Signaling in Skeletal Muscle ⁶³ TOB in Osteoblast Signaling ⁶³	12.93	TNF MAPK10 MAPK1 JUN ITGB2 ITGAM
43	Relaxin signaling pathway ³⁶ Show member pathways Estrogen signaling pathway ³⁶ Growth hormone synthesis, secretion and action ³⁶ Relaxin receptors ⁶⁵	12.93	OPRM1 MAPK10 MAPK1 JUN GNAI1 GNA15
44	Common Cytokine Receptor Gamma-Chain Family Signaling Pathways ⁶⁴ Show member pathways Adipokines and Insulin Signaling Pathways ⁶⁴ Development Thrombopoietin-regulated cell processes ²² IL-15 Signaling Pathways ⁶⁴ IL-2 Signaling Pathways ⁶⁴ IL-21 Signaling Pathways ⁶⁴ IL-4 Signaling Pathways ⁶⁴ IL-7 Signaling Pathways ⁶⁴ IL-9 Pathway ⁶³ IL-9 Signaling Pathways ⁶⁴ Immune response IL-9 signaling pathway ²²	12.92	TNF MAPK1 JUN IL6 FOS
45	Ras signaling pathway ³⁶ Show member pathways Rap1 signaling pathway ³⁶	12.92	MAPK10 MAPK1 ITGB2 ITGAM GNAI1 CALM1
46	NF-KappaB Family Pathway ⁶³ Show member pathways NF-KappaB (p50-p65) Pathway ⁶³	12.89	TNF TLR4 MYD88 IL6 IL1B CALM1
47	Immune response NFAT in immune response ²² Show member pathways Immune response CD28 signaling ²² Immune response ICOS pathway in T-helper cell ²² Immune response T cell receptor signaling pathway ²²	12.89	TNF MAPK10 MAPK1 JUN IL10 GNA15
48	Development Endothelin-1/EDNRA signaling ²² Show member pathways Cytoskeleton remodeling FAK signaling ²² Development Endothelin-1/EDNRA transactivation of EGFR ²² GnRH signaling pathway ³⁶ Inflammatory mediator regulation of TRP channels ³⁶	12.89	MAPK10 MAPK1 JUN IL1B GNAZ GNAI1
49	4-1BB Pathway ⁶³ Show member pathways CD27 Pathway ⁶³ CD40 Signaling ⁶³ CMV and MAPK Pathways ⁶³ NF-KappaB Activation by EBV ⁶³ NF-kappaB Activation by Viruses ⁶³ PKR Pathway ⁶³ SUMO Pathway ⁶³ TNFR2 Pathway ⁶³	12.87	TNF MAPK10 MAPK1 JUN IL1B FOS
50	Development HGF signaling pathway ²² Show member pathways Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1 ²² Apoptosis and survival NGF signaling pathway ²² Apoptosis and survival Role of CDK5 in neuronal death and survival ²² Development Neurotrophin family signaling ²² MET activates PTPN11 ⁶⁵ MET activates STAT3 ⁶⁵ Neurotrophin signaling pathway ³⁶ Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) ¹ Signaling of Hepatocyte Growth Factor Receptor ¹	12.86	MAPK10 MAPK1 JUN FOS CALM1

Sources

GO Terms for Pertussis

Cellular components related to Pertussis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	10.1	TNF TLR4 OPRM1 MYD88 MAPK10 MAPK1
2	membrane raft	GO:0045121	9.35	TNF OPRM1 ITGB2 ITGAM GNAI1
3	transcription factor AP-1 complex	GO:0035976	9.32	JUN FOS
4	integrin alphaM-beta2 complex	GO:0034688	9.16	ITGB2 ITGAM
5	heterotrimeric G-protein complex	GO:0005834	8.92	GNAZ GNAI1 GNA15 GNA14

Biological processes related to Pertussis according to GeneCards Suite gene sharing:

(show top 50) (show all 63)

#	Name	GO ID	Score	Top Affiliating Genes
1	G protein-coupled receptor signaling pathway	GO:0007186	10.27	OPRM1 GNAZ GNAI1 GNA15 GNA14 CXCL8
2	positive regulation of transcription by RNA polymerase II	GO:0045944	10.26	TNF TLR4 JUN IL6 IL1B IL10
3	positive regulation of transcription, DNA-templated	GO:0045893	10.13	TNF MAPK1 JUN IL6 IL1B IL10
4	signal transduction	GO:0007165	10.13	TLR4 OPRM1 MYD88 MAPK10 MAPK1 IL6
5	immune response	GO:0006955	10.12	TNF TLR4 IL6 IL1B IL10 CXCL8
6	positive regulation of gene expression	GO:0010628	10.09	TNF TLR4 MYD88 MAPK1 IL6 IL1B
7	negative regulation of cell proliferation	GO:0008285	10.09	OPRM1 JUN IL6 IL1B IL10 CXCL8
8	positive regulation of ERK1 and ERK2 cascade	GO:0070374	10.03	TNF TLR4 OPRM1 JUN
9	leukocyte migration	GO:0050900	10.02	TNF ITGB2 ITGAM IL1B
10	MAPK cascade	GO:0000165	10.02	TNF MAPK10 MAPK1 IL1B CALM1
11	positive regulation of I-kappaB kinase/NF-kappaB signaling	GO:0043123	10	TNF TLR4 MYD88 IL1B
12	aging	GO:0007568	9.97	MAPK1 JUN ITGB2 IL10 FOS
13	Fc-epsilon receptor signaling pathway	GO:0038095	9.96	MAPK10 MAPK1 JUN FOS CALM1
14	positive regulation of DNA-binding transcription factor activity	GO:0051091	9.94	TNF IL6 IL1B IL10
15	platelet activation	GO:0030168	9.93	MAPK1 IL6 GNA15 GNA14
16	phagocytosis	GO:0006909	9.91	TLR4 MYD88 ITGB2
17	activation of MAPK activity	GO:0000187	9.91	TNF TLR4 MAPK10 MAPK1 IL1B
18	response to glucocorticoid	GO:0051384	9.9	TNF IL6 IL10
19	apoptotic signaling pathway	GO:0097190	9.9	TNF TLR4 ITGAM
20	positive regulation of NIK/NF-kappaB signaling	GO:1901224	9.89	TNF TLR4 IL1B
21	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GO:0007193	9.89	OPRM1 GNAZ GNAI1
22	positive regulation of smooth muscle cell proliferation	GO:0048661	9.88	TNF JUN IL6
23	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.88	TNF TLR4 MYD88 ITGB2 IL6 IL1B
24	positive regulation of vascular smooth muscle cell proliferation	GO:1904707	9.87	TNF JUN IL10
25	positive regulation of interferon-gamma production	GO:0032729	9.87	TNF TLR4 IL1B
26	positive regulation of neuron death	GO:1901216	9.85	ITGB2 ITGAM FOS
27	cellular response to reactive oxygen species	GO:0034614	9.85	MAPK1 JUN FOS
28	cellular response to cadmium ion	GO:0071276	9.85	MAPK1 JUN FOS
29	negative regulation of interleukin-6 production	GO:0032715	9.85	TNF TLR4 IL10
30	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO:0007188	9.85	GNAZ GNAI1 GNA15 GNA14
31	positive regulation of interleukin-6 secretion	GO:2000778	9.84	TNF TLR4 IL1B
32	positive regulation of pri-miRNA transcription by RNA polymerase II	GO:1902895	9.83	JUN IL10 FOS
33	positive regulation of nitric oxide biosynthetic process	GO:0045429	9.83	TNF TLR4 ITGB2 IL1B
34	positive regulation of JAK-STAT cascade	GO:0046427	9.82	TNF IL6 IL10
35	negative regulation of neurogenesis	GO:0050768	9.8	TNF IL6 IL1B
36	lipopolysaccharide-mediated signaling pathway	GO:0031663	9.8	TNF TLR4 MAPK1 IL1B
37	cellular response to lipopolysaccharide	GO:0071222	9.8	TNF TLR4 MYD88 IL6 IL1B IL10
38	positive regulation of chemokine production	GO:0032722	9.78	TNF TLR4 IL6
39	regulation of DNA-binding transcription factor activity	GO:0051090	9.78	MAPK10 MAPK1 JUN FOS
40	positive regulation of glial cell proliferation	GO:0060252	9.77	TNF IL6 IL1B
41	toll-like receptor 4 signaling pathway	GO:0034142	9.77	TLR4 ITGB2 ITGAM
42	positive regulation of interleukin-6 production	GO:0032755	9.77	TNF TLR4 MYD88 IL6 IL1B
43	microglial cell activation	GO:0001774	9.76	TNF JUN ITGB2 ITGAM
44	positive regulation of heterotypic cell-cell adhesion	GO:0034116	9.75	TNF IL1B IL10
45	positive regulation of MHC class II biosynthetic process	GO:0045348	9.73	TLR4 IL10
46	negative regulation of synaptic transmission	GO:0050805	9.73	IL1B GNAI1
47	negative regulation of lipid storage	GO:0010888	9.73	TNF IL6
48	positive regulation of interleukin-8 production	GO:0032757	9.73	TNF TLR4 MYD88 IL1B
49	endothelial cell apoptotic process	GO:0072577	9.72	TNF IL10
50	regulation of establishment of endothelial barrier	GO:1903140	9.71	TNF IL1B

Molecular functions related to Pertussis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:0005515	10.36	TNF TLR4 OPRM1 MYD88 MAPK10 MAPK1
2	cytokine activity	GO:0005125	9.65	TNF IL6 IL1B IL10 CXCL8
3	G protein-coupled receptor binding	GO:0001664	9.46	GNAZ GNAI1 GNA15 GNA14
4	complement component C3b binding	GO:0001851	9.37	ITGB2 ITGAM
5	G protein-coupled serotonin receptor binding	GO:0031821	9.32	GNAZ GNAI1
6	G-protein beta/gamma-subunit complex binding	GO:0031683	9.26	GNAZ GNAI1 GNA15 GNA14
7	guanyl nucleotide binding	GO:0019001	8.92	GNAZ GNAI1 GNA15 GNA14

Sources

Sources for Pertussis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Pertussis

Aliases & Classifications for Pertussis

MalaCards integrated aliases for Pertussis:

Characteristics:

Orphanet epidemiological data:

Classifications:

External Ids:

Summaries for Pertussis

Related Diseases for Pertussis

Diseases related to Pertussis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Pertussis:

Symptoms & Phenotypes for Pertussis

UMLS symptoms related to Pertussis:

GenomeRNAi Phenotypes related to Pertussis according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Pertussis:

Drugs & Therapeutics for Pertussis

Drugs for Pertussis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 71 / NDF-RT 50 :

Cochrane evidence based reviews: bordetella infections

Genetic Tests for Pertussis

Anatomical Context for Pertussis

The Foundational Model of Anatomy Ontology organs/tissues related to Pertussis:

MalaCards organs/tissues related to Pertussis:

Publications for Pertussis

Articles related to Pertussis:

Genes for Pertussis

Genes related to Pertussis (0 elite genes):

Variations for Pertussis

Expression for Pertussis

Pathways for Pertussis

Pathways related to Pertussis according to KEGG:

Pathways related to Pertussis according to GeneCards Suite gene sharing:

GO Terms for Pertussis

Cellular components related to Pertussis according to GeneCards Suite gene sharing:

Biological processes related to Pertussis according to GeneCards Suite gene sharing:

Molecular functions related to Pertussis according to GeneCards Suite gene sharing:

Sources for Pertussis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :