MCID: PTR002
MIFTS: 29

Petroclival Meningioma

Categories: Bone diseases, Cancer diseases
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Aliases & Classifications for Petroclival Meningioma

MalaCards integrated aliases for Petroclival Meningioma:

Name: Petroclival Meningioma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:7818
NCIt 49 C5278
UMLS 71 C1335395

Summaries for Petroclival Meningioma

MalaCards based summary: Petroclival Meningioma is related to microcystic meningioma and sensorineural hearing loss, and has symptoms including headache and seizures. An important gene associated with Petroclival Meningioma is POLR3C (RNA Polymerase III Subunit C), and among its related pathways/superpathways are Myometrial relaxation and contraction pathways and Basigin interactions. Affiliated tissues include bone, trigeminal ganglion and spinal cord, and related phenotype is hearing/vestibular/ear.

Related Diseases for Petroclival Meningioma

Diseases related to Petroclival Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 134)
# Related Disease Score Top Affiliating Genes
1 microcystic meningioma 30.1 TRAF7 NF2
2 sensorineural hearing loss 29.1 TMPRSS4 TMPRSS3 NF2 GJB6 GJB2 CLRN2
3 meningioma, familial 11.0
4 abducens palsy 10.4
5 trigeminal neuralgia 10.3
6 deafness, autosomal recessive 111 10.2 TMPRSS3 CLRN2
7 neurilemmoma 10.2
8 deafness, autosomal recessive 83 10.2 TMPRSS4 TMPRSS3
9 congenital cytomegalovirus 10.2 GJB6 GJB2
10 nonsyndromic hearing loss and deafness, dfnb1 10.2 GJB6 GJB2
11 dfnb1 10.2 GJB6 GJB2
12 viral labyrinthitis 10.2 GJB6 GJB2
13 deafness, autosomal dominant 59 10.2 GJB6 GJB2
14 deafness, autosomal dominant 3b 10.2 GJB6 GJB2
15 deafness, autosomal dominant 6 10.2 GJB6 GJB2
16 deafness, autosomal dominant 12 10.2 GJB6 GJB2
17 keratitis-ichthyosis-deafness syndrome, autosomal dominant 10.2 GJB6 GJB2
18 deafness, autosomal dominant 64 10.2 GJB6 GJB2
19 deafness, autosomal recessive 98 10.2 TMPRSS4 TMPRSS3
20 deafness, autosomal recessive 42 10.2 TMPRSS4 TMPRSS3
21 deafness, autosomal recessive 15 10.1 GJB6 GJB2
22 deafness, autosomal recessive 1b 10.1 GJB6 GJB2
23 parkinson disease, late-onset 10.1
24 papillon-lefevre syndrome 10.1
25 hydrocephalus 10.1
26 bell's palsy 10.1
27 acoustic neuroma 10.1
28 facial paralysis 10.1
29 keratoderma, palmoplantar, with deafness 10.1 GJB6 GJB2
30 auditory neuropathy, autosomal dominant 1 10.1 TMPRSS3 GJB2
31 deafness, autosomal dominant 3a 10.1 GJB2 CLRN2
32 deafness, autosomal recessive 9 10.1 TMPRSS3 GJB2
33 foramen magnum meningioma 10.1 TRAF7 NF2
34 bart-pumphrey syndrome 10.1 GJB6 GJB2
35 tuberculum sellae meningioma 10.1 TRAF7 NF2
36 psammomatous meningioma 10.1 TRAF7 NF2
37 sella turcica neoplasm 10.1 TRAF7 NF2
38 optic nerve sheath meningioma 10.1 TRAF7 NF2
39 olfactory groove meningioma 10.1 TRAF7 NF2
40 angiomatous meningioma 10.1 TRAF7 NF2
41 palmoplantar keratoderma and congenital alopecia 1 10.1 GJB6 GJB2
42 intraneural perineurioma 10.1 TRAF7 NF2
43 anterior cranial fossa meningioma 10.1 TRAF7 NF2
44 chordoid meningioma 10.1 TRAF7 NF2
45 deafness, autosomal dominant 9 10.1 GJB6 GJB2
46 deafness, autosomal recessive 29 10.1 TMPRSS3 GJB2
47 transitional meningioma 10.1 TRAF7 NF2
48 clouston syndrome 10.1 GJB6 GJB2
49 secretory meningioma 10.1 TRAF7 NF2
50 spinal canal and spinal cord meningioma 10.1 TRAF7 NF2

Graphical network of the top 20 diseases related to Petroclival Meningioma:



Diseases related to Petroclival Meningioma

Symptoms & Phenotypes for Petroclival Meningioma

UMLS symptoms related to Petroclival Meningioma:


headache; seizures

MGI Mouse Phenotypes related to Petroclival Meningioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hearing/vestibular/ear MP:0005377 9.02 CLRN2 GJB2 GJB6 NF2 TMPRSS3

Drugs & Therapeutics for Petroclival Meningioma

Search Clinical Trials, NIH Clinical Center for Petroclival Meningioma

Genetic Tests for Petroclival Meningioma

Anatomical Context for Petroclival Meningioma

Organs/tissues related to Petroclival Meningioma:

MalaCards : Bone, Trigeminal Ganglion, Spinal Cord, Brain, Cortex, Lung

Publications for Petroclival Meningioma

Articles related to Petroclival Meningioma:

(show top 50) (show all 216)
# Title Authors PMID Year
1
Endoscope-Assisted Microsurgical Resection of a Large Petroclival Meningioma Using a Retrosigmoid Approach: 2-Dimensional Operative Video. 62
36227257 2022
2
Commentary: Endoscope-Assisted Microsurgical Resection of a Large Petroclival Meningioma Using a Retrosigmoid Approach: 2-Dimensional Operative Video. 62
36227240 2022
3
Modified Transpetrosal-Transtentorial Approach for Resection of Large and Giant Petroclival Meningioma: Technical Nuance and Surgical Experiences. 62
34794193 2022
4
Microsurgical Resection of Giant Petroclival Meningioma via the Posterior Petrosal Approach: 2-Dimensional Operative Video. 62
35963609 2022
5
Surgical results of 158 petroclival meningiomas with special focus on standard craniotomies. 62
36103000 2022
6
[CASE SERIES OF EARLY NEUROIMAGING IN PATIENTS WITH VASCULAR RISK FACTORS AND ISOLATED SIX CRANIAL NERVE PALSY, DEMONSTRATING THE DILEMMA OF EARLY IMAGING]. 62
36315208 2022
7
Combined Posterior Transpetrosal: Presigmoid and Subtemporal Resection of a Large Petroclival Meningioma. 62
36352568 2022
8
The role of stereotactic radiosurgery in the management of petroclival meningioma: a systematic review. 62
35717468 2022
9
Blood-brain Barrier Damage is Pivotal for SARS-CoV-2 Infection to the Central Nervous System. 62
36050226 2022
10
Mortality and morbidity in surgically treated patients with petroclival meningiomas: a systematic review and meta-analysis of case series. 62
35109722 2022
11
Commentary: Microsurgical Resection of a Petroclival Meningioma via a Suboccipital Approach: Technical Nuances and Anatomical Considerations: 2-Dimensional Operative Video. 62
35726939 2022
12
Microsurgical Resection of a Petroclival Meningioma via a Suboccipital Approach: Technical Nuances and Anatomical Considerations: 2-Dimensional Operative Video. 62
35726938 2022
13
Increased MIB-1 Labeling Index Is Associated with Abducens Nerve Morbidity in Primary Sporadic Petroclival Meningioma Surgery: Beyond Location and Approach. 62
35877258 2022
14
Real-time vessel segmentation and reconstruction for virtual fixtures for an active handheld microneurosurgical instrument. 62
35296950 2022
15
Primary Dural Repair Using Titanium Microclips Following Lateral Skull Base Surgery. 62
35832979 2022
16
Endoscopic Endonasal Approaches to the Clivus with No Violation of the Nasopharynx: Surgical Anatomy and Clinical Illustration. 62
35832971 2022
17
Combined Petrosal Approach for Resection of Petroclival Meningioma: 2-Dimensional Operative Video. 62
35189415 2022
18
Intracranial necrotising sarcoid granulomatosis mimicking petroclival meningioma. 62
35580943 2022
19
Endoscopic Far-Lateral Supracerebellar Infratentorial Approach for Petroclival Region Meningioma: Surgical Technique and Clinical Experience. 62
35315837 2022
20
Extended middle fossa approach for resection of a petroclival meningioma and vestibular schwannoma. 62
36284993 2022
21
Combined transpetrosal approach for giant petroclival meningioma: 2-dimensional operative video. 62
36284994 2022
22
Combined petrosal approach for resection of a large left petroclival meningioma. 62
36284995 2022
23
Endoscopic endonasal transpetroclival approach for recurrent bilateral petroclival meningioma. 62
36284997 2022
24
Approach selection for resection of petroclival meningioma. 62
36284998 2022
25
Anterior petrosal (Kawase) approach to petroclival meningioma: 2-dimensional operative video. 62
36284999 2022
26
Stereotactic radiosurgery in the management of petroclival meningiomas: a systematic review and meta-analysis of treatment outcomes of primary and adjuvant radiosurgery. 62
35301638 2022
27
Endoscopic-assisted combined transcrusal anterior petrosal approach for resection of large petroclival meningioma: operative video and nuances of technique. 62
36285004 2022
28
Modified Dolenc-Kawase anterior petrous rhomboid approach for petroclival meningioma: surgical nuances and complication avoidance. 62
36284996 2022
29
Endoscopic endonasal transclival petroclival meningioma resection. 62
36285000 2022
30
Right posterior petrosectomy for resection of petroclival meningioma. 62
36285001 2022
31
Microsurgical resection of a large petroclival meningioma via translabyrinthine approach combined with middle fossa craniotomy. 62
36285002 2022
32
Combined petrosal approach for a huge retroclival meningioma preserving the cranial nerves. 62
36285003 2022
33
Comparative analysis of the combined petrosal and the pretemporal transcavernous anterior petrosal approach to the petroclival region. 62
34507299 2022
34
Anterior transpetrosal approach: experiences in 274 cases over 33 years. Technical variations, operated patients, and approach-related complications. 62
34388716 2022
35
Does general comorbidity impact the postoperative outcomes after surgery for large and giant petroclival meningiomas? 62
34117561 2022
36
A rare case of petroclival meningioma: the role of neuroimaging in the diagnosis and prognosis. 62
36196417 2022
37
A Retrospective Evaluation of the Retrosigmoidal Approach for Petroclival Meningioma Surgery and Prognostic Factors Affecting Clinical Outcome. 62
35433418 2022
38
[Surgical approaches to petroclival meningiomas Part 2: narrative review of what we learned with 30 cases]. 62
36447900 2022
39
Clival Paraganglioma, Case Report and Literature Review. 62
35844205 2022
40
Contralateral Trigeminal Neuralgia Due to Left Petroclival Meningioma an Extremely Rare Presentation: A Case Report. 62
34747842 2021
41
Study of comparative surgical exposure to the petroclival region using patient-specific, petroclival meningioma virtual reality models. 62
34333476 2021
42
Piezosurgery for safe and efficient petrous bone cutting in cerebellopontine angle and petroclival meningioma surgery. 62
34119287 2021
43
Petroclival Meningioma Leading to Trigeminal Neuralgia: A Kawase Approach Application. 62
33989821 2021
44
Differences in surgical outcome between petroclival meningioma and anterior petrous meningioma. 62
33555377 2021
45
Total Petrosectomy for the Total Resection of Sphenopetroclival Meningioma: 2-Dimensional Operative Video. 62
33928386 2021
46
Contralateral sudden sensorineural hearing loss after resection of petroclival meningioma. 62
33823561 2021
47
Electrophysiological predictors of hearing deterioration based on AEP monitoring during petroclival meningioma resection. 62
32671694 2021
48
Two-Stage Double Petrosal Approach for the Total Resection of Petroclival-Cavernous Meningioma: 2-Dimensional Operative Video. 62
33649755 2021
49
Use of Neuroanatomic Knowledge and Neuronavigation System for a Safe Anterior Petrosectomy. 62
33921434 2021
50
Prediction of trigeminal nerve position based on the main feeding artery in petroclival meningioma. 62
32424648 2021

Variations for Petroclival Meningioma

Expression for Petroclival Meningioma

Search GEO for disease gene expression data for Petroclival Meningioma.

Pathways for Petroclival Meningioma

Pathways related to Petroclival Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 GJB6 GJB2 ATP1B3 ATP1B1
2
Show member pathways
10.39 ATP1B3 ATP1B1

GO Terms for Petroclival Meningioma

Cellular components related to Petroclival Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 connexin complex GO:0005922 9.26 GJB6 GJB2
2 sodium:potassium-exchanging ATPase complex GO:0005890 8.92 ATP1B3 ATP1B1

Biological processes related to Petroclival Meningioma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 sodium ion export across plasma membrane GO:0036376 9.8 ATP1B3 ATP1B1
2 cellular potassium ion homeostasis GO:0030007 9.78 ATP1B3 ATP1B1
3 membrane repolarization GO:0086009 9.76 ATP1B3 ATP1B1
4 sensory perception of sound GO:0007605 9.76 TMPRSS3 GJB6 GJB2 CLRN2
5 gap junction assembly GO:0016264 9.73 GJB6 GJB2
6 positive regulation of potassium ion import across plasma membrane GO:1903288 9.71 ATP1B3 ATP1B1
7 positive regulation of potassium ion transmembrane transporter activity GO:1901018 9.67 ATP1B3 ATP1B1
8 cell communication by electrical coupling GO:0010644 9.62 GJB2 GJB6
9 gap junction-mediated intercellular transport GO:1990349 9.56 GJB6 GJB2
10 positive regulation of sodium ion export across plasma membrane GO:1903278 9.26 ATP1B3 ATP1B1
11 cellular sodium ion homeostasis GO:0006883 9.1 TMPRSS3 ATP1B3 ATP1B1

Molecular functions related to Petroclival Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gap junction channel activity GO:0005243 9.26 GJB6 GJB2
2 gap junction channel activity involved in cell communication by electrical coupling GO:1903763 8.92 GJB6 GJB2

Sources for Petroclival Meningioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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