MCID: PTR002
MIFTS: 25

Petroclival Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Petroclival Meningioma

MalaCards integrated aliases for Petroclival Meningioma:

Name: Petroclival Meningioma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7818
NCIt 50 C5278
UMLS 70 C1335395

Summaries for Petroclival Meningioma

MalaCards based summary : Petroclival Meningioma is related to meningioma, familial and intracranial meningioma, and has symptoms including seizures and headache. An important gene associated with Petroclival Meningioma is EXTL1 (Exostosin Like Glycosyltransferase 1). Affiliated tissues include cortex, spinal cord and trigeminal ganglion, and related phenotype is hearing/vestibular/ear.

Related Diseases for Petroclival Meningioma

Diseases related to Petroclival Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 10.9
2 intracranial meningioma 10.9
3 secretory meningioma 10.9
4 lymphoplasmacyte-rich meningioma 10.9
5 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
6 facial paralysis 10.1
7 neurilemmoma 10.1
8 deafness, autosomal recessive 8 10.1 TMPRSS4 TMPRSS3
9 deafness, autosomal recessive 83 10.1 TMPRSS4 TMPRSS3
10 deafness, autosomal dominant 7 10.1 TMPRSS4 TMPRSS3
11 deafness, autosomal recessive 98 10.1 TMPRSS4 TMPRSS3
12 auditory system disease 10.0 TMPRSS4 TMPRSS3
13 abducens palsy 10.0
14 seizures, benign familial neonatal, 1 10.0
15 hemifacial spasm, familial 10.0
16 otitis media 10.0
17 trigeminal neuralgia 10.0
18 chondrosarcoma 10.0
19 werner syndrome 10.0
20 ataxia and polyneuropathy, adult-onset 10.0
21 abducens nerve disease 10.0
22 hydrocephalus 10.0
23 oculomotor nerve paralysis 10.0
24 polycystic ovary syndrome 10.0
25 pseudobulbar palsy 10.0
26 acoustic neuroma 10.0
27 amenorrhea 10.0
28 gonadal dysgenesis 10.0
29 mixed gonadal dysgenesis 10.0
30 hypogonadism 10.0
31 hyperostosis 10.0
32 transient cerebral ischemia 10.0
33 turner syndrome 10.0
34 cranial nerve palsy 10.0
35 posterior cerebral artery infarction 10.0
36 microcystic meningioma 10.0
37 infertility 10.0
38 third cranial nerve disease 10.0
39 cerebrospinal fluid leak 10.0
40 pseudobulbar affect 10.0
41 rosai-dorfman disease 10.0
42 cerebral atrophy 10.0
43 hemifacial spasm 10.0
44 paresthesia 10.0
45 deafness, autosomal recessive 4, with enlarged vestibular aqueduct 9.9 TMPRSS4 TMPRSS3
46 skull base cancer 9.9 TRAF7 TMPRSS3 EXTL1
47 skull base meningioma 9.9 TRAF7 TMPRSS3 EXTL1
48 autosomal dominant nonsyndromic deafness 9.8 TMPRSS4 TMPRSS3
49 febrile seizures 9.7 SCN8A HCN1
50 autism 9.0 TDO2 SCN8A MBP HCN1

Graphical network of the top 20 diseases related to Petroclival Meningioma:



Diseases related to Petroclival Meningioma

Symptoms & Phenotypes for Petroclival Meningioma

UMLS symptoms related to Petroclival Meningioma:


seizures; headache

MGI Mouse Phenotypes related to Petroclival Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hearing/vestibular/ear MP:0005377 8.92 HCN1 MBP SCN8A TMPRSS3

Drugs & Therapeutics for Petroclival Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparative Study Between Different Approaches to CPA -Petroclival Meningiomas Unknown status NCT03462914

Search NIH Clinical Center for Petroclival Meningioma

Genetic Tests for Petroclival Meningioma

Anatomical Context for Petroclival Meningioma

MalaCards organs/tissues related to Petroclival Meningioma:

40
Cortex, Spinal Cord, Trigeminal Ganglion

Publications for Petroclival Meningioma

Articles related to Petroclival Meningioma:

(show top 50) (show all 167)
# Title Authors PMID Year
1
Microsurgical Resection of Petroclival Meningioma via the Posterior Petrosal Approach: Three-Dimensional Operative Video. 61
33338671 2021
2
The Zap-X Radiosurgical System in the Treatment of Intracranial Tumors: A Technical Case Report. 61
33442727 2021
3
Two-Stage Double Petrosal Approach for the Total Resection of Petroclival-Cavernous Meningioma: 2-Dimensional Operative Video. 61
33649755 2021
4
Differences in surgical outcome between petroclival meningioma and anterior petrous meningioma. 61
33555377 2021
5
Rare Tumor-to-Tumor Metastases Involving Lung Adenocarcinoma to Petroclival Meningiomas. 61
32730974 2020
6
Effectiveness of high-frequency cervical spinal cord stimulation in the treatment of refractory trigeminal neuropathy: A case report. 61
33019405 2020
7
Treatment Outcome of Gamma Knife Radiosurgery for Petroclival Meningiomas: Retrospective Analysis of a Single Institution Experience. 61
33118341 2020
8
Antineutrophil Cytoplasmic Antibody-Associated Hypertrophic Pachymeningitis Mimicking Petroclival Meningioma. 61
30601196 2020
9
Association between the Symptomatic Appearance of Dural Arteriovenous Fistula and Trigeminal Ganglion Radiofrequency Thermocoagulation. 61
32695561 2020
10
Letter to the Editor. Management of petroclival meningioma. 61
32736361 2020
11
Electrophysiological predictors of hearing deterioration based on AEP monitoring during petroclival meningioma resection. 61
32671694 2020
12
A clinical study of ocular motor nerve functions after petroclival meningioma resection. 61
32100111 2020
13
Successful stereotactic radiotherapy of meningiomas in a patient with Cowden syndrome: a case report. 61
32312055 2020
14
Prediction of trigeminal nerve position based on the main feeding artery in petroclival meningioma. 61
32424648 2020
15
Retrosigmoid Transtentorial Resection of a Petroclival Meningioma: 2-Dimensional Operative Video. 61
31162584 2020
16
Intracranial Hemorrhage from Meningioma: 2 Novel Risk Factors. 61
31698125 2020
17
Sellar trough technique for endoscopic endonasal transclival repair. 61
32494378 2020
18
Absence of contrast enhancement in a petroclival meningioma: Case report and systematic literature review. 61
33365181 2020
19
Anterior Transpetrosal Approach for Petroclival Meningioma: Operative Nuances. 61
32129238 2020
20
Petroclival meningiomas and the petrosal approach. 61
32586485 2020
21
Patient-specific 3-dimensionally printed models for neurosurgical planning and education. 61
31786547 2019
22
Delayed Dural Arteriovenous Fistula at the Transverse-Sigmoid Sinus Secondary to Petroclival Meningioma Surgery Via Far Lateral Approach. 61
31022135 2019
23
Petroclival Meningioma Presenting With an Ipsilateral Sixth Nerve Palsy and a Contralateral Homonymous Quadrantanopia: A Unique and Topographically Localizing Syndrome. 61
30664101 2019
24
First MRI With New Cochlear Implant With Rotatable Internal Magnet System and Proposal for Standardization of Reporting Magnet-Related Artifact Size. 61
31219967 2019
25
Combined Petrosal Approach for Resection of Petroclival Meningioma with Endoscopic Assistance: Operative Video and Technical Nuances. 61
31143597 2019
26
Retrosigmoid Intradural Suprameatal Approach for Petroclival Meningioma. 61
31143599 2019
27
Staged Approach for Petroclival Meningioma Resection. 61
31143605 2019
28
Combined Transpetrosal Approach With Preservation of Superior Petrosal Vein Drainage for a Cerebellopontine Angle Epidermoid Cyst Extending Into Meckel's Cave: 3-Dimensional Operative Video. 61
30452703 2019
29
Petroclival meningiomas: long-term outcomes of multimodal treatments and management strategies based on 30 years of experience at a single institution. 61
31075775 2019
30
Pathologic Laughter as an Early and Unusual Presenting Symptom of Petroclival Meningioma: a Case Report and Review of the Literature. 61
30554003 2019
31
Preservation of Venous Drainage in Middle Fossa During Combined Transpetrosal Approach for Petroclival Meningioma. 61
30529519 2019
32
Susceptibility-Weighted Imaging of Deep Venous Congestion in Petroclival Meningioma. 61
30236813 2019
33
The Retrosigmoid Approach: Workhorse for Petroclival Meningioma Surgery. 61
30937033 2019
34
Clinical outcomes and survival analysis for petroclival meningioma patients receiving surgical resection: an analysis of 176 cases. 61
31308738 2019
35
Resection of a Petroclival Meningioma via the Endoscope-Assisted Retrosigmoid Approach: 2-D Operative Video. 61
30456038 2018
36
Piezosurgery-A Safe Technique to Perform Lateral Suboccipital Craniotomy? 61
29300964 2018
37
Combined Presigmoid and Retrosigmoid Approach to Petroclival Meningiomas. 61
30456041 2018
38
THE RARE CASE OF MIXED GONADAL DYSGENESIS, MOSAIC KARYOTYPE, PETROCLIVAL MENINGIOMA AND IDIOPATHIC HYPERDEHYDROEPIANDROSTERONISM. 61
31149308 2018
39
Resection of Petroclival Meningioma Through Retrosigmoid Approach-Concepts and Nuances: 3- Dimensional Operative Video. 61
29444298 2018
40
Toward Improving Safety in Neurosurgery with an Active Handheld Instrument. 61
30014286 2018
41
Usefulness of Preoperative Simulation in Skull Base Approach: A Case Report. 61
30210993 2018
42
Surgical excision of large-to-giant petroclival meningiomas focusing on the middle fossa approaches: The lessons learnt. 61
30233019 2018
43
Petroclival Meningiomas: Factors Determining the Choice of Approach. 61
30009118 2018
44
Safety profile of superior petrosal vein (the vein of Dandy) sacrifice in neurosurgical procedures: a systematic review. 61
29961377 2018
45
Expression of trans-membrane serine protease 3 (TMPRSS3) in the human organ of Corti. 61
29460002 2018
46
Tumor Progression Following Petroclival Meningioma Subtotal Resection: A Volumetric Study. 61
28541487 2018
47
Erratum: Combined petrosal approach for petroclival meningioma. 61
29291294 2018
48
One burr-hole craniotomy: Modified presigmoid approach in Helsinki Neurosurgery. 61
30283715 2018
49
Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry. 61
29487598 2018
50
Dramatic radiographic response resulting in cerebrospinal fluid rhinorrhea associated with sunitinib therapy in recurrent atypical meningioma: case report. 61
27935362 2017

Variations for Petroclival Meningioma

Expression for Petroclival Meningioma

Search GEO for disease gene expression data for Petroclival Meningioma.

Pathways for Petroclival Meningioma

GO Terms for Petroclival Meningioma

Biological processes related to Petroclival Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homotetramerization GO:0051289 8.96 TDO2 HCN1
2 myelination GO:0042552 8.62 SCN8A MBP

Molecular functions related to Petroclival Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scavenger receptor activity GO:0005044 9.16 TMPRSS4 TMPRSS3
2 sodium channel activity GO:0005272 8.96 SCN8A HCN1
3 voltage-gated sodium channel activity GO:0005248 8.62 SCN8A HCN1

Sources for Petroclival Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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