MCID: PHC001
MIFTS: 22

Phacolytic Glaucoma

Categories: Neuronal diseases

Aliases & Classifications for Phacolytic Glaucoma

MalaCards integrated aliases for Phacolytic Glaucoma:

Name: Phacolytic Glaucoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:12570
ICD9CM 34 365.51
SNOMED-CT 67 32893002
UMLS 70 C0152137

Summaries for Phacolytic Glaucoma

Disease Ontology : 12 A phacogenic glaucoma that is characterized by acute onset of open-angle glaucoma secondary to a leaking mature or hypermature cataract and has symptom chronic progressive vision loss with acute onset of pain, redness, and blurry vision. Phacolytic glaucomas are caused by direct obstruction of aqueous outflow pathways from leaking cataractous lens proteins.

MalaCards based summary : Phacolytic Glaucoma is related to cataract and intraocular pressure quantitative trait locus, and has symptoms including chronic progressive vision loss An important gene associated with Phacolytic Glaucoma is COL4A1 (Collagen Type IV Alpha 1 Chain). Affiliated tissues include eye, retina and endothelial.

Wikipedia : 73 Phacolytic glaucoma (PG) is a form of glaucoma which is caused due to a leaking mature or immature... more...

Related Diseases for Phacolytic Glaucoma

Diseases related to Phacolytic Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 cataract 30.0 PXDN FOXE3 COL4A1
2 intraocular pressure quantitative trait locus 10.9
3 uveitis 10.5
4 endophthalmitis 10.3
5 open-angle glaucoma 10.3
6 phacoanaphylactic uveitis 10.3
7 keratitis, hereditary 10.2
8 isolated ectopia lentis 10.2
9 corneal edema 10.2
10 mature cataract 10.2
11 morgagni cataract 10.2
12 glaucoma, primary open angle 10.0
13 ectopia lentis et pupillae 10.0
14 megalocornea 10.0
15 macular degeneration, age-related, 1 10.0
16 ifap syndrome 2 10.0
17 hypopyon 10.0
18 corneal abscess 10.0
19 absolute glaucoma 10.0
20 acute closed-angle glaucoma 10.0
21 neovascular glaucoma 10.0
22 optic nerve disease 10.0
23 neurilemmoma 10.0
24 homocystinuria 10.0
25 senile cataract 10.0
26 hypoglycemia 10.0
27 axenfeld-rieger syndrome, type 1 9.9 FOXE3 B3GLCT
28 sclerocornea 9.9 FOXE3 B3GLCT
29 aniridia 1 9.8 FOXE3 B3GLCT
30 corneal disease 9.8 FOXE3 B3GLCT
31 walker-warburg syndrome 9.7 COL4A1 B3GLCT
32 axenfeld-rieger syndrome 9.7 FOXE3 COL4A1 B3GLCT
33 juvenile glaucoma 9.7 PXDN FOXE3
34 anterior segment dysgenesis 1 9.5 PXDN FOXE3 COL4A1
35 glaucoma 3, primary congenital, a 9.5 PXDN FOXE3 COL4A1
36 axenfeld-rieger syndrome, type 3 9.5 PXDN FOXE3 COL4A1
37 microphthalmia 9.4 PXDN FOXE3 COL4A1
38 anterior segment dysgenesis 9.3 PXDN FOXE3 COL4A1 B3GLCT
39 peters-plus syndrome 9.3 PXDN FOXE3 COL4A1 B3GLCT

Comorbidity relations with Phacolytic Glaucoma via Phenotypic Disease Network (PDN):


Morgagni Cataract

Graphical network of the top 20 diseases related to Phacolytic Glaucoma:



Diseases related to Phacolytic Glaucoma

Symptoms & Phenotypes for Phacolytic Glaucoma

Symptoms:

12
  • chronic progressive vision loss

Drugs & Therapeutics for Phacolytic Glaucoma

Search Clinical Trials , NIH Clinical Center for Phacolytic Glaucoma

Genetic Tests for Phacolytic Glaucoma

Anatomical Context for Phacolytic Glaucoma

MalaCards organs/tissues related to Phacolytic Glaucoma:

40
Eye, Retina, Endothelial

Publications for Phacolytic Glaucoma

Articles related to Phacolytic Glaucoma:

(show top 50) (show all 97)
# Title Authors PMID Year
1
[Morgagnian Cataract with Associated Phacolytic Glaucoma and Anterior Chamber Polychromatic Crystals: A Case Report]. 61
33202432 2021
2
Phacolytic glaucoma in contralateral pseudophakes. 61
31709635 2020
3
Phacolytic glaucoma: A nearly forgotten entity. 61
30950286 2020
4
Indirect choroidal neovascularization secondary to a posterior-segment intraocular foreign body - case report. 61
32316922 2020
5
The Untoward Effect of Neglected Cataracts: Phacolytic Glaucoma. 61
32672675 2019
6
Rare atypical presentation of phacolytic glaucoma as non-resolving microbial keratitis with endophthalmitis. 61
31527222 2019
7
Lens induced glaucoma in a tertiary eye care centre in Western Nepal. 61
32792690 2019
8
Synchysis scintillans mimicking phacolytic glaucoma in a traumatic eye. 61
30887660 2019
9
Phacolytic Glaucoma. 61
32672583 2019
10
Acute Phacolytic Glaucoma and Morgagnian Cataract. 61
30973585 2019
11
Sticky Cortical Matter Behind Intact Posterior Capsule in Phacolytic Glaucoma. 61
30045090 2018
12
First Described Case of Anterior and Posterior Segment Crystals in Phacolytic Glaucoma. 61
28234682 2017
13
Lens induced glaucoma: An experience in tertiary eye care center in eastern Nepal. 61
28478470 2016
14
Case report: atypical presentation of Mycobacterium tuberculosis uveitis preceding nodular scleritis. 61
26511718 2015
15
A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy. 61
25407294 2014
16
Lens-induced glaucoma in a tertiary centre in northeast of Malaysia. 61
25883765 2014
17
Lens-Induced Glaucoma: The Need to Spread Awareness about Early Management of Cataract among Rural Population. 61
24555131 2013
18
Sequelae of neglected senile cataract. 61
25606266 2013
19
Ocular snow storm: an unusual presentation of phacolytic glaucoma. 61
22843757 2012
20
Phacolytic glaucoma: are there 2 forms? 61
21423037 2012
21
Unusual presentation of phacolytic glaucoma: simulating microbial keratitis. 61
22606478 2011
22
Clinical characteristics of endophthalmitis after an injection of intravitreal antivascular endothelial growth factor. 61
20616683 2010
23
Safety and efficacy of manual small incision cataract surgery for phacolytic glaucoma. 61
17322465 2007
24
Safety and efficacy of manual small incision cataract surgery for phacolytic glaucoma. 61
17322458 2007
25
Spontaneous recovery in phacolytic glaucoma. 61
16246793 2005
26
Phacolytic glaucoma in Fuch's heterochromic uveitis. 61
15829757 2005
27
[Ocular hypertension as the principal indicator of onset of uveal melanoma]. 61
15692891 2005
28
The contribution of aqueous humor cytology in the differential diagnosis of anterior uvea inflammations. 61
15385197 2004
29
Vitrectomy for phacolytic glaucoma in a patient with ectopia lentis et pupillae. 61
12640414 2003
30
[Result of operations for hyper-mature cataract complicated with phacolytic glaucoma]. 61
12664478 2002
31
A prospective study of 413 cases of lens-induced glaucoma in Nepal. 61
15884514 2001
32
Vitrectomy for phacolytic glaucoma in a patient with homocystinuria. 61
10612517 1999
33
Iatrogenic cataract after laser-assisted in situ keratomileusis. 61
10577595 1999
34
Effects of age, sex, cataract, and cataract surgery on serum gamma-crystallin concentration. 61
10420118 1999
35
Intraocular pressure control and visual outcome in patients with phacolytic glaucoma managed by extracapsular cataract extraction with or without posterior chamber intraocular lens implantation. 61
9824859 1998
36
Management of phacolytic glaucoma: experience of 135 cases. 61
10085625 1998
37
[Phacotopic glaucoma]. 61
9713194 1998
38
An alternate way to manage patients with morgagnian cataracts and phacolytic glaucoma. 61
9475014 1997
39
Vitreous opacities in phacolytic glaucoma. 61
8895204 1996
40
Lens induced glaucomas--visual results and risk factors for final visual acuity. 61
9018992 1996
41
Cataract extraction and intraocular lens implantation in eyes with phacomorphic or phacolytic glaucoma. 61
8784641 1996
42
Endocapsular surgery and capsular bag fixation of intraocular lenses in phacolytic glaucoma. 61
8778358 1996
43
Phacolytic glaucoma--its treatment by planned extracapsular cataract extraction with posterior chamber intraocular lens implantation. 61
7829178 1994
44
Advanced cataract in Singapore--its prognosis and complications. 61
8129350 1993
45
Phacolytic glaucoma and lens-induced uveitis. 61
8132409 1993
46
[The etiopathology of phacoantigenic uveitis and phacolytic glaucoma]. 61
1520677 1992
47
Lens-induced glaucoma. 61
1483374 1992
48
Cytokines in human intraocular inflammation. 61
1424744 1992
49
Comparison of specular microscopy and examination of aspirate in phacolytic glaucoma. 61
2314848 1990
50
[An uncommon clinical form of phakolytic glaucoma]. 61
2605755 1989

Variations for Phacolytic Glaucoma

Expression for Phacolytic Glaucoma

Search GEO for disease gene expression data for Phacolytic Glaucoma.

Pathways for Phacolytic Glaucoma

GO Terms for Phacolytic Glaucoma

Molecular functions related to Phacolytic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.62 PXDN COL4A1

Sources for Phacolytic Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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