MCID: PHR003
MIFTS: 56

Pharyngitis

Categories: Oral diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Pharyngitis

MalaCards integrated aliases for Pharyngitis:

Name: Pharyngitis 12 74 54 43 15 71
Acute Pharyngitis 12 17 71 32
Chronic Pharyngitis 12 71 32
Pharyngeal Diseases 43 71
Chronic Pharyngitis and Nasopharyngitis 12
Chronic Pharyn/nasopharyngitis 12
Persistent Sore Throat 12
Sore Throat - Chronic 12
Chronic Sore Throat 12
Pharyngeal Disorder 12
Pharyngitis - Acute 12
Pharyngeal Disease 12
Acute Sore Throat 12
Inflamed Throat 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2275
ICD9CM 34 462 472 478.20
UMLS 71 C0001344 C0031345 C0031350 more

Summaries for Pharyngitis

Disease Ontology : 12 An upper respiratory tract disease involving inflammation of the throat or pharynx resulting from bacterial, viral, fungal infections or irritants like pollutants or chemical substances and smoking. The infection is often referred to as sore throat. The symptoms include pain during swallowing, enlarged tonsils coated with a white discharge, runny nose, cough and slight fever.

MalaCards based summary : Pharyngitis, also known as acute pharyngitis, is related to tonsillitis and cyclic neutropenia, and has symptoms including recurrent pharyngitis, sore throat and acute sore throat nos. An important gene associated with Pharyngitis is MIR452 (MicroRNA 452), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Benzydamine and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, tonsil and heart.

Wikipedia : 74 Pharyngitis is inflammation of the back of the throat, known as the pharynx. It typically results in a... more...

Related Diseases for Pharyngitis

Diseases related to Pharyngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1031)
# Related Disease Score Top Affiliating Genes
1 tonsillitis 33.0 LACTB IL1B CXCL8
2 cyclic neutropenia 32.8 IL1B CXCL8 CSF2
3 rheumatic fever 32.7 MYOM2 HLA-DRB1 CD40LG
4 smallpox 32.5 IL1RN IL1B CSF2
5 sleep apnea 31.7 IL1B CXCL8 CRP
6 haemophilus influenzae 31.4 LACTB CXCL8
7 aspiration pneumonia 31.2 LACTB CRP CD40LG
8 laryngitis 31.1 IL1B CRP CD40LG
9 chlamydia 31.1 IL1B CXCL8 CSF2 CRP CD40LG
10 rheumatic heart disease 31.1 MYOM2 IL1B HLA-DRB1
11 gastroesophageal reflux 31.0 PTGS2 IL1RN IL1B CXCL8
12 otitis media 31.0 LACTB IL1B CXCL8 CRP CD40LG
13 esophagitis 30.9 PTGS2 IL1B CXCL8
14 lymphadenitis 30.9 IL1B CXCL8 CRP
15 streptococcal toxic-shock syndrome 30.9 MYOM2 CXCL8
16 urethritis 30.8 CXCL8 CRP CD40LG
17 chlamydia pneumonia 30.8 CXCL8 CRP CD40LG
18 epiglottitis 30.7 LACTB CRP CD40LG
19 scarlet fever 30.7 MYOM2 ETV5 CRP CD40LG
20 fasciitis 30.6 MYOM2 IL1RN CXCL8
21 candidiasis 30.6 IL1B CXCL8 CSF2 CD40LG
22 syphilis 30.6 LACTB HLA-DRB1 CRP CD40LG
23 appendicitis 30.5 IL1B CXCL8 CRP
24 stomatitis 30.5 NLRP3 MEFV IL1RN IL1B CXCL8 CSF2
25 osteomyelitis 30.4 NLRP3 IL1RN IL1B CXCL8
26 endocarditis 30.4 LACTB CXCL8 CRP
27 acquired immunodeficiency syndrome 30.4 IL1B CSF2 CRP CD40LG
28 bronchitis 30.4 LACTB IL1B CXCL8 CRP CD40LG
29 bronchopneumonia 30.4 CXCL8 CRP CD40LG
30 respiratory failure 30.4 IL1RN IL1B CXCL8 CRP
31 orbital plasma cell granuloma 30.4 CRP CD40LG
32 reactive arthritis 30.3 IL1B CXCL8 CRP
33 gastritis 30.3 PTGS2 IL1RN IL1B CXCL8
34 aphthous stomatitis 30.3 SPAG7 NLRP3 MEFV IL1RN IL1B CXCL8
35 purpura 30.3 MEFV CRP CD40LG
36 bacterial pneumonia 30.2 LACTB CXCL8 CRP CD40LG
37 toxic shock syndrome 30.2 MYOM2 IL1RN IL1B CXCL8 CRP CD40LG
38 crohn's disease 30.2 NLRP3 IL1B HLA-DRB1 CXCL8 CRP
39 cerebral palsy 30.2 PTGS2 IL1B CXCL8
40 exanthem 30.2 NLRP3 MEFV IL1RN CXCL8 CSF2 CRP
41 herpes zoster 30.1 HLA-DRB1 CRP CD40LG
42 peptic esophagitis 30.1 PTGS2 IL1B CXCL8
43 colitis 30.1 PTGS2 IL1B HLA-DRB1 CXCL8
44 kawasaki disease 30.1 IL1B CRP CD40LG
45 maxillary sinusitis 30.1 LACTB CRP CD40LG
46 newborn respiratory distress syndrome 30.1 IL1B FCGR1A CXCL8
47 preterm premature rupture of the membranes 30.1 IL1B CXCL8 CRP
48 urticaria 30.1 PTGS2 NLRP3 CRP CD40LG
49 polyarteritis nodosa 30.1 MEFV HLA-DRB1 CRP
50 pyelonephritis 30.1 IL1B CXCL8 CRP

Comorbidity relations with Pharyngitis via Phenotypic Disease Network (PDN): (show all 12)


Acute Cystitis Anxiety
Bronchitis Deficiency Anemia
Esophagitis Heart Disease
Hypertension, Essential Hypothyroidism
Intermediate Coronary Syndrome Laryngitis
Oral Candidiasis Swallowing Disorders

Graphical network of the top 20 diseases related to Pharyngitis:



Diseases related to Pharyngitis

Symptoms & Phenotypes for Pharyngitis

UMLS symptoms related to Pharyngitis:


recurrent pharyngitis, sore throat, acute sore throat nos, throat irritation

Drugs & Therapeutics for Pharyngitis

Drugs for Pharyngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 265)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzydamine Approved Phase 4 642-72-8, 100-46-9 7504
2
Azithromycin Approved Phase 4 83905-01-5 55185 447043
3
Tyrothricin Approved Phase 4 1404-88-2
4
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
5
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
6
Budesonide Approved Phase 4 51333-22-3 63006 5281004
7
Acetaminophen Approved Phase 4 103-90-2 1983
8
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 5281106 54677470
9
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
10
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
11
Fluconazole Approved, Investigational Phase 4 86386-73-4 3365
12
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
13
Clarithromycin Approved Phase 4 81103-11-9 84029
14
leucovorin Approved Phase 4 58-05-9 6006 143
15
Pemetrexed Approved, Investigational Phase 4 150399-23-8, 137281-23-3 446556 60843
16
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560 441411
17
Montelukast Approved Phase 4 158966-92-8 5281040
18
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
19
Sotalol Approved Phase 4 959-24-0, 3930-20-9 5253
20
Menthol Approved Phase 4 2216-51-5 16666
21
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
22
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
23
Racepinephrine Approved Phase 4 329-65-7 838
24
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
25
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
26
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
27
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
28
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
29 Tinoridine Investigational Phase 4 24237-54-5
30
Beclomethasone Phase 4 4419-39-0 20469
31 Chlorhexidine gluconate Phase 4
32 Disinfectants Phase 4
33 Anti-Infective Agents, Local Phase 4
34 Benzalkonium Compounds Phase 4
35 HIV Protease Inhibitors Phase 4
36
protease inhibitors Phase 4
37 Hormone Antagonists Phase 4
38 BB 1101 Phase 4
39 glucocorticoids Phase 4
40 Hormones Phase 4
41 Antipyretics Phase 4
42 Platelet Aggregation Inhibitors Phase 4
43 lysine Phase 4
44 Ketoprofen lysine Phase 4
45 Fibrinolytic Agents Phase 4
46 Cytochrome P-450 Enzyme Inhibitors Phase 4
47 Antifungal Agents Phase 4
48 Steroid Synthesis Inhibitors Phase 4
49 Cytochrome P-450 CYP2C9 Inhibitors Phase 4
50 Cytochrome P-450 CYP3A Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 212)
# Name Status NCT ID Phase Drugs
1 Group A Streptococcal Pharyngitis: Six Days Amoxicillin, oR Six Days Placebo in Children Between 3 and 15 Years Old:a Randomized, Double Blinded, Multicentred, Non-inferiority Trial Unknown status NCT03264911 Phase 4 Amoxicillin or Placebo
2 Effect on Postoperative Sore Throat of Lidocaine Jelly Application Over the Endotracheal Tube of Tapered-shaped Cuff Unknown status NCT02952157 Phase 4 Lidocaine jelly application;Normal saline application
3 Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain Unknown status NCT01681667 Phase 4 Ibuprofen
4 Does Beclomethasone Instillation Above the Cuff of Endotracheal Tubes Decrease the Occurrence of Postoperative Sore Throat? A Randomized Controlled Trial Unknown status NCT02687100 Phase 4 Beclomethasone;Placebo
5 Safety and Efficacy of Tinoridine in the Treatment of Pain and Inflammation in Patients With Acute Tonsillitis and/or Acute Pharyngitis: a Randomized, Double-blind Study Versus Placebo Completed NCT01224756 Phase 4 Tinoridine HCl;Placebo
6 A Multi-centre, Randomized, Placebo-controlled, Double-blind, Parallel-group Study Investigating Safety and Efficacy of a Sore Throat Lozenge in the Symptomatic Treatment of Patients With Acute Pharyngitis Completed NCT03323528 Phase 4 Benzalkonium Chloride-Benzocaine Topical;Placebo Oral Tablet
7 Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies in the Non-complicated Acute Respiratory Tract Infections in General Practice Completed NCT01363531 Phase 4
8 Multicenter, Open, Randomized Comparative Trial To Compare Bacteriological And Clinical Efficacy Of Azithromycin Versus Amoxicillin In Children With Streptococcus Tonsillitis Completed NCT00643539 Phase 4 Zithromax;Clamoxyl
9 Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour : a Randomised Controlled Trial in Primary Care. Completed NCT01398696 Phase 4
10 MISTRAL (Mouthwash In Sore Throat Relief: Antiinflammatory vs. Local Anesthetic Therapy) "Efficacy and Tolerability of Ketoprofen Lysine Salt as a Mouthwash in Acute Phlogosis of the Pharyngeal Cavity; Multicentre, Randomized, Single-blind, Parallel-group Comparison Versus Benzidamine Hydrochloride" Completed NCT02178293 Phase 4 Benzidamine hydrochloride;Ketoprofen lysine salt
11 Randomized, Open-label, Controlled Trial to Assess the Clinical Efficacy and Safety of Meloxicam Suspension 0.25 mg/kg/Day Once a Day, Versus Diclofenac 1 mg/kg/Day Twice a Day or Nimesulide 4 mg/kg/Day Twice a Day, for Five Days in the Treatment of Patients With Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4 Meloxicam;Diclofenac;Nimesulide
12 Recurrent Throat Infections and Tonsillectomy Completed NCT00547391 Phase 4
13 Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients: a Randomized Controlled Trial Completed NCT03074968 Phase 4 Benzydamine Hydrochloride;Normal saline
14 The Effect Of Two Packing Types For Throat Pain And Postoperative Nausea And Vomiting During Maxillofacial Surgery Completed NCT03574246 Phase 4 chlorhexidine gluconate %0,12 benzydamine hydrochloride %0,15
15 Comparison Between Xylocaine Gel as Endotracheal Cuff Lubricant Versus Dexamethasone 8 mg Intravenously or Both for Sore Throat Prevention Following Intubation: Interventional Study Completed NCT02682134 Phase 4 xylocaine;Dexamethasone;Xylocaine and Dexamethasone
16 A Phase IV Randomized Study of the Use of Fluconazole as Chronic Suppressive Therapy Versus Episodic Therapy in HIV Positive Subjects With Recurrent Oropharyngeal Candidiasis Completed NCT00000951 Phase 4 Fluconazole
17 Double-blind, Randomized, Placebo-controlled, Single Dose, Parallel Group Study Evaluating Efficacy and Safety of 1000 mg Acetylsalicylic Acid and 1000 mg Paracetamol in Adult Patients With Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
18 Combined Effect of Intravenous Lidocaine and Dexamethasone on Postoperative Sore Throat, Cough and Hoarseness. A Randomized Controlled Trial Completed NCT01990781 Phase 4 LD: Lidocaine and dexamethasone;L:Lidocaine;D: Dexamethasone;N: Normal saline (placebo)
19 Open-Label Single-Arm Phase IV Study of Pemetrexed in Taiwanese Patients With Advanced Non-Small Cell Lung Cancer Who Have Had Prior Chemotherapy Completed NCT00380718 Phase 4 pemetrexed
20 Comparison of Azithromycin or Clarithromycin in 3drugs Protocol of H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
21 Role of Montelukast in Asthma and Allergic Rhinitis Patients Completed NCT03380975 Phase 4 Montelukast 10mg
22 Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Pain in Patients Presenting to the Emergency Department With Sore Throat: A Double-Blinded, Randomized, Controlled Trial Completed NCT03768882 Phase 4 paracetamol;Dexketoprofen
23 Comparing the Efficacies Between the Spray of S.L. Spray Solution and Difflam and Acular to Release Postoperative Sore Throat Completed NCT02608788 Phase 4 S.L.®;Difflam Forte ®;Acular®;placebo
24 TEAM (Trial on Efficacy and Quality of Life Among Asthmatic Patient With Montelukast) Completed NCT03096327 Phase 4 Montelukast;Placebo
25 The Effect of Systemic Prophylactic Dexamethasone on the Incidence of Postoperative Sore Throat in Patients Undergoing Ambulatory Laparoscopic Gynecologic Surgery: A Prospective, Randomized, Double Blinded, Placebo Controlled Trial Completed NCT01052038 Phase 4 Placebo administration;Dexamethasone 0.05mg/kr administration;Dexamethasone 0.1mg/kg
26 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Completed NCT00560586 Phase 4 Budesonide;placebo
27 Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant; Impact on Postoperative Sore Throat and Haemodynamics Recruiting NCT03031808 Phase 4 Lidocaine spray (2%);Muscle Relaxant (Rocuronium)
28 A Pilot and Feasibility Study to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs Recruiting NCT02347111 Phase 4 Flecainide;Sotalol
29 Randomized Clinical Trial Examining Use of Adjunct EXPAREL for Post-tonsillectomy Pain Management in Adults Active, not recruiting NCT03420638 Phase 4 Adjunct Exparel (bupivacaine liposome suspension 1.3%)
30 Open Clinical Trial to Assess Safety and Efficacy of the Sore Throat Lozenges in Patients With Acute Sore Throats Active, not recruiting NCT04139681 Phase 4 A. Vogels Sore Throat lozenges
31 A Randomized Controlled Clinical Trial of Streptococcus Group A-negative Acute Tonsillitis in Primary Health Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment Not yet recruiting NCT04083417 Phase 4 Phenoxymethylpenicillin
32 Local, Phase IV, Multicenter, Double-blind, Randomized, Parallel, With Two Treatment Arms, Placebo-controlled Study to Evaluate the Reduction of Inflammatory Symptoms in the Treatment of Bacterial Pharyngitis With Ketoprofen and Amoxicillin in Pediatric Patients. Terminated NCT00799838 Phase 4 Ketoprofen;Placebo (for Ketoprofen);Amoxicillin
33 A Multicenter, Single-blind, Randomized, Placebo-controlled Comparative Study on Efficacy and Safety of the Lysobact Complete Spray®, Tantum Verde® Spray and Pharyngal® Oromucosal Spray in the Treatment of Acute Sore Throat in Common Cold Unknown status NCT03282045 Phase 3 Lysobact Complete Sprey;Tantum Verde® Spray;Pharyngal® Oromucosal Spray;Placebo
34 Evaluation of Accuracy of Rapid Tests for Group A Beta Hemolytic Streptococci in Out-patients With Sore Throat From Acute Pharyngitis at Siriraj Hospital Unknown status NCT02623985 Phase 3
35 Efficacy of Benzydamine Hydrochloride Dripping at Endotracheal Tube Cuff for Prevention of Postoperative Sore Throat Unknown status NCT01637883 Phase 3 benzydamine HCl
36 Study of Efficacy and Safety of V0498 Versus Placebo in Acute Sore Throat Pain. Completed NCT01785862 Phase 3 Ibuprofen 25 mg;Placebo
37 Multicentric Randomized Double Blind Double Dummy Placebo Controlled Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray in Comparison to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats Completed NCT00707902 Phase 3 chlorhexidine/lidocaine;echinacea/sage
38 A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multicentre Trial to Assess the Efficacy and Safety of Ambroxol Lozenges 20 mg (Hard Boiled Lozenges) Versus Placebo for the Relief of Sore Throat Pain in Patients With Acute Pharyngitis Completed NCT03583658 Phase 3 ambroxol BIH1526;placebo
39 A Single-Dose, Randomized, Double-Blind, Placebo-Controlled Onset-of-Action Study Utilizing the Double-Stopwatch Method Completed NCT01986361 Phase 3 flurbiprofen;placebo
40 A Randomized, Double-Blind, Placebo-Controlled Multiple-Dose Study to Determine the Efficacy, Onset, and Duration of Action of Flurbiprofen 8.75 mg Lozenge Compared to Its Vehicle Control Lozenge in Patients With Painful Pharyngitis Completed NCT01049334 Phase 3 Placebo;Flurbiprofen
41 A Repeat-Dose, Multi-Centre, Randomized, Double-Blind, Placebo-Controlled, Study to Determine the Safety and Efficacy of Flurbiprofen 8.75 mg Lozenge Compared to Its Vehicle Control Lozenge in Patients With Painful Pharyngitis Completed NCT01048866 Phase 3 placebo;flurbiprofen;acetaminophen 650mg
42 Prospective, Multicenter, Open, Randomized, Parallel, Clinical Study for Comparative Assessment of Efficacy and Safety of Angal S, Topical Spray [Menthol], 0,5 mg + 2 mg / 1 ml (Sandoz d.d., Slovenia), and ANTI-ANGIN® FORMULA, Topical Metered Spray, 0,12 mg + 0,24 mg / Dose (OOO "Valeant", Russia) in Treatment of Patients With Uncomplicated Acute Infectious and Inflammatory Diseases of the Pharynx, Accompanied by a Sore Throat Completed NCT03095508 Phase 3 Angal S, topical spray [Menthol];ANTI-ANGIN® FORMULA, topical metered spray
43 A Phase III, Investigator Blind, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of APC-231 Sprinkle QD for 7 Days vs Penicillin VK 10 mg/kg QID for 10 Days in Pediatric Patients With Streptococcus Pyogenes Completed NCT00100126 Phase 3 Amoxicillin Pulsatile Release Multiparticluate Sprinkle
44 A Phase III, Randomized, Double-Blind, Double-Dummy Multicenter Study to Evaluate the Efficacy and Safety of 775 mg APC-111 MP Tablet QD for 7 Days vs Penicillin VK 250 mg QID for 10 Days in Patients With Streptococcus Pyogenes Completed NCT00095368 Phase 3 Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)
45 A Double Blind, Randomized, Placebo-Controlled Comparison of the Efficacy, Safety, and Tolerability of Celecoxib 100-150 mg, Including Initial Doses of 50 and 100 mg, and Placebo in the Symptomatic Treatment of Patients With Painful Pharyngitis Completed NCT00402987 Phase 3 celecoxib;celecoxib followed by placebo;celecoxib;placebo
46 Efficacy and Tolerability of Ambroxol Lozenges 20mg in Relieving the Pain of Sore Throat in Adolescent Patients With Acute Viral Pharyngitis - A Randomised, Double-blind, Placebo-controlled Parallel Group Study. AMBROSIA: Ambroxol Lozenges In Sore Throat In Adolescents Completed NCT00144274 Phase 3 Ambroxol Lozenge
47 Efficacy and Tolerability of Ambroxol Lozenge 20 mg in Relieving Pain of Sore Throat in Patients With Acute Viral Pharyngitis-A Randomised, Double-blind,Placebo- and Active-controlled Parallel Group Study Completed NCT00148499 Phase 3 Ambroxol hydrochloride (Mucoangin?);benzocaine
48 Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain Completed NCT01453400 Phase 3 Acetylsalicylic Acid (Aspirin, BAY1019036) + placebo;Acetaminophen + placebo;Placebo
49 A Phase III, Multicenter Study to Evaluate the Safety/Efficacy of APC-111 MP Tablet QD vs. Penicillin VK QID Both for 10 Days Treatment of Pharyngitis Secondary to S.Pyogenes in Adolescents/Adults Completed NCT00242281 Phase 3 APC-111 MP Tablet, 775 mg
50 A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin SR Versus Three-Day Azithromycin for the Treatment of Group A β-Hemolytic Streptococcal Pharyngitis/Tonsillitis in Adolescents and Adults Completed NCT00644293 Phase 3 azithromycin (Zithromax);placebo;azithromycin SR;placebo

Search NIH Clinical Center for Pharyngitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


cefditoren
Guaifenesin

Cochrane evidence based reviews: pharyngitis

Genetic Tests for Pharyngitis

Anatomical Context for Pharyngitis

MalaCards organs/tissues related to Pharyngitis:

40
Testes, Tonsil, Heart, Lung, Thyroid, Skin, Colon

Publications for Pharyngitis

Articles related to Pharyngitis:

(show top 50) (show all 5267)
# Title Authors PMID Year
1
The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. 46
21098571 2010
2
Potential mechanisms for failure to eradicate group A streptococci from the pharynx. 54 61
10506234 1999
3
Phenoxymethyl penicillin versus co-amoxiclav in the treatment of acute streptococcal pharyngitis, and the role of beta-lactamase activity in saliva. 54 61
8647754 1996
4
Treatment of beta-hemolytic streptococcal pharyngitis with cefaclor or penicillin. Efficacy and interaction with beta-lactamase-producing organisms in the pharynx. 54 61
1990041 1991
5
Lack of influence of beta-lactamase-producing flora on recovery of group A streptococci after treatment of acute pharyngitis. 54 61
2123240 1990
6
The immunology of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; what can the tonsils reveal. A literature review. 61
31786522 2020
7
Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome: A debate about diagnosis and treatment in children continues. 61
31866107 2020
8
Safety and immunogenicity of a 30-valent M protein-based group a streptococcal vaccine in healthy adult volunteers: A randomized, controlled phase I study. 61
31843270 2020
9
T serotyping of group a streptococcus isolated from patients with pharyngitis or streptococcal toxic shock syndrome in Japan between 2005 and 2017. 61
31735631 2020
10
Clinical Features of Group A Streptococcus in Children With Pharyngitis: Carriers versus Acute Infection. 61
32040013 2020
11
Indications and classes of outpatient antibiotic prescriptions in Japan: A descriptive study using the national database of electronic health insurance claims, 2012-2015. 61
31730926 2020
12
Comparative genomic analysis of Streptococcus dysgalactiae subspecies dysgalactiae, an occasional cause of zoonotic infection. 61
31859005 2020
13
Prevalence of Group A Streptococcus in Primary Care Patients and the Utility of C-Reactive Protein and Clinical Scores for Its Identification in Thailand. 61
31889507 2020
14
Comparison of bronchial and nasal allergen provocation in children and adolescents with bronchial asthma and house dust mite sensitization. 61
31660641 2020
15
Polygalasaponin F treats mice with pneumonia induced by influenza virus. 61
31446589 2020
16
Practice of parents and pharmacists regarding antibiotics use in pediatrics: A 2017 cross-sectional study in Lebanese community pharmacies. 61
31111612 2020
17
Performance of the new 'Eurofever/PRINTO classification criteria' in FMF patients. 61
31471011 2020
18
EBV-positive T/NK-associated lymphoproliferative disorders of childhood: A complete autopsy report. 61
32031127 2020
19
Prevalence of Group A β-hemolytic Streptococcal Throat Carriage and Prospective Pilot Surveillance of Streptococcal Sore Throat in Ugandan School Children. 61
31972290 2020
20
Liu Shen Wan inhibits influenza a virus and excessive virus-induced inflammatory response via suppression of TLR4/NF-κB signaling pathway in vitro and in vivo. 61
31972325 2020
21
Anti-influenza A virus mechanism of three representative compounds from Flos Trollii via TLRs signaling pathways. 61
32004628 2020
22
Comparison of antibiotic prescriptions in adults and children with upper respiratory tract infections in Bangka Tengah primary health care centers. 61
31926085 2020
23
Changes over an 8-year period in Streptococcus pyogenes emm types in pharyngeal isolates from non-invasive infection patients at a pediatric facility. 61
32009072 2020
24
Postbiotics for Preventing and Treating Common Infectious Diseases in Children: A Systematic Review. 61
32024037 2020
25
Pediatrician's approach to diagnosis and management of group A streptococcal pharyngitis. 61
31984431 2020
26
The impact of law enforcement on dispensing antibiotics without prescription: a multi-methods study from Saudi Arabia. 61
31834825 2020
27
Human-origin Lactobacillus salivarius AR809 protects against immunosuppression in S. aureus-induced pharyngitis via Akt-mediated NF-κB and autophagy signaling pathways. 61
31957758 2020
28
Optimization for microbial incorporation and efficiency of photodynamic therapy using variation on curcumin formulation. 61
31923633 2020
29
The group A Streptococcus accessory protein RocA: regulatory activity, interacting partners and influence on disease potential. 61
31660653 2020
30
Effects of Video Discharge Instructions on Patient Understanding: A Prospective, Randomized Trial. 61
32000193 2020
31
Naturally-acquired protection against upper respiratory symptoms involving group A Streptococcus in a longitudinal cohort study. 61
31955205 2020
32
Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums. 61
31899452 2020
33
Performance of recently proposed periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome criteria in a region endemic for familial Mediterranean fever. 61
31346686 2020
34
Stay the Course: Targeted Evaluation, Accurate Diagnosis, and Treatment of Streptococcal Pharyngitis Prevent Acute Rheumatic Fever. 61
31561955 2020
35
Rheumatic Fever and Rheumatic Heart Disease in Children. 61
31925717 2020
36
Short-Term Systemic Corticosteroids: Appropriate Use in Primary Care. 61
31939645 2020
37
Guideline Adherence and Antibiotic Utilization by Community Pediatricians, Private Urgent Care Centers, and a Pediatric Emergency Department. 61
31609128 2020
38
Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study. 61
31953740 2020
39
Empiric Treatment for Acute Pharyngitis. 61
31790183 2019
40
Immune Dysregulation in the Tonsillar Microenvironment of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. 61
31807979 2019
41
[Clinical observation of acupuncture at Qianlianquan (Extra) and eight confluent points on chronic pharyngitis]. 61
31820603 2019
42
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). 61
31886897 2019
43
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Ambroxol Hard-Boiled Lozenges in Patients with Acute Pharyngitis. 61
32026411 2019
44
A Bayesian Spatiotemporal Analysis of Pediatric Group A Streptococcal Infections. 61
31867406 2019
45
Sore throat turned to be a bronchogenic carcinoma with superior vena cava syndrome. 61
31822531 2019
46
Efficacy of gummy lozenges containing Erysimum as ancillary treatment in children with sore throat. 61
30761819 2019
47
Manifestations of enterovirus D68 and high seroconversion among children attending a kindergarten. 61
31164279 2019
48
Upper eyelid oedema in a patient with pharyngitis/exudative tonsillitis and malaise: Hoagland sign in infectious mononucleosis. 61
31871012 2019
49
Primary Infectious Mononucleosis Masquerading as Post-operative Fever in a Young Patient with Cemento-ossifying Fibroma of the Skull Base. 61
31938618 2019
50
Occurrence of patients compared in a pediatric practice and pediatric hospital outpatient clinic. 61
31129994 2019

Variations for Pharyngitis

Expression for Pharyngitis

Search GEO for disease gene expression data for Pharyngitis.

Pathways for Pharyngitis

Pathways related to Pharyngitis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.93 PTGS2 NLRP3 MEFV IL1RN IL1B HLA-DRB1
2
Show member pathways
13.26 PTGS2 IL1RN IL1B HLA-DRB1 FCGR1A CXCL8
3 12.29 NLRP3 IL1B CXCL8 CSF2
4
Show member pathways
12.23 PTGS2 IL1B CXCL8 CSF2
5 12.15 FCGR1A ETV5 CXCL8 CSF2
6
Show member pathways
12.12 PTGS2 IL1RN IL1B CXCL8
7
Show member pathways
12.08 PTGS2 IL1B HLA-DRB1 FCGR1A CD40LG
8 11.98 NLRP3 MEFV IL1B CXCL8 CARD8
9 11.92 NLRP3 MEFV IL1B CXCL8
10 11.82 PTGS2 IL1B CXCL8 CD40LG
11 11.8 IL1B CXCL8 CSF2 CD1A
12 11.75 IL1B HLA-DRB1 CXCL8 CSF2
13 11.7 IL1B CXCL8 CSF2
14 11.67 NLRP3 IL1B CXCL8
15 11.65 IL1B CSF2 CD1A
16
Show member pathways
11.61 PTGS2 CXCL8 CSF2 CD40LG
17 11.57 IL1B CXCL8 CSF2
18 11.55 IL1B HLA-DRB1 FCGR1A CSF2 CD1A
19 11.52 PTGS2 IL1RN IL1B CSF2
20 11.44 IL1B CXCL8 CD40LG
21 11.17 NLRP3 MEFV IL1B CARD8
22 11.16 IL1B HLA-DRB1 CSF2
23
Show member pathways
11.15 PTGS2 IL1B CXCL8 CSF2 CD40LG
24 10.91 PTGS2 CXCL8 CRP
25 10.71 PTGS2 IL1RN IL1B CXCL8 CSF2

GO Terms for Pharyngitis

Cellular components related to Pharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NLRP3 inflammasome complex GO:0072559 8.96 NLRP3 CARD8
2 inflammasome complex GO:0061702 8.62 NLRP3 CARD8

Biological processes related to Pharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.65 PTGS2 IL1RN IL1B CXCL8 CSF2
2 neutrophil chemotaxis GO:0030593 9.63 IL1RN IL1B CXCL8
3 immune response GO:0006955 9.56 IL1RN IL1B HLA-DRB1 FCGR1A CXCL8 CSF2
4 cellular response to lipopolysaccharide GO:0071222 9.55 NLRP3 IL1RN IL1B CXCL8 CSF2
5 negative regulation of blood vessel diameter GO:0097756 9.43 PTGS2 CRP
6 positive regulation of prostaglandin biosynthetic process GO:0031394 9.4 PTGS2 IL1B
7 interleukin-1 beta production GO:0032611 9.37 NLRP3 IL1B
8 positive regulation of fever generation GO:0031622 9.32 PTGS2 IL1B
9 inflammatory response GO:0006954 9.23 PTGS2 NLRP3 MEFV IL1RN IL1B CXCL8

Molecular functions related to Pharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL1RN IL1B CXCL8 CSF2 CD40LG

Sources for Pharyngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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