MCID: PHR008
MIFTS: 14

Pharynx Squamous Cell Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Pharynx Squamous Cell Carcinoma

MalaCards integrated aliases for Pharynx Squamous Cell Carcinoma:

Name: Pharynx Squamous Cell Carcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050921

Summaries for Pharynx Squamous Cell Carcinoma

Disease Ontology : 12 A pharynx cancer that has material basis in squamous cells.

MalaCards based summary : Pharynx Squamous Cell Carcinoma is related to squamous cell carcinoma and malignant fibrous histiocytoma. An important gene associated with Pharynx Squamous Cell Carcinoma is COL11A1 (Collagen Type XI Alpha 1 Chain), and among its related pathways/superpathways is Signaling events mediated by PRL. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pharynx Squamous Cell Carcinoma

Diseases related to Pharynx Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.1
2 malignant fibrous histiocytoma 9.9 RECQL4 MFHAS1
3 tongue disease 9.8 MIR196A1 MAU2

Symptoms & Phenotypes for Pharynx Squamous Cell Carcinoma

GenomeRNAi Phenotypes related to Pharynx Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

26 (show all 21)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-1 9.87 COL11A1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.87 MFHAS1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.87 MFHAS1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.87 COL11A1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.87 TUSC3
6 Increased shRNA abundance (Z-score > 2) GR00366-A-15 9.87 COL11A1 MFHAS1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.87 TUSC3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-170 9.87 COL11A1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-179 9.87 COL11A1 RECQL4
10 Increased shRNA abundance (Z-score > 2) GR00366-A-18 9.87 COL11A1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-181 9.87 COL11A1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.87 TUSC3
13 Increased shRNA abundance (Z-score > 2) GR00366-A-200 9.87 COL11A1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.87 COL11A1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.87 COL11A1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-69 9.87 TUSC3
17 Increased shRNA abundance (Z-score > 2) GR00366-A-79 9.87 COL11A1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.87 MFHAS1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-89 9.87 RECQL4
20 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.87 COL11A1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.87 TUSC3

Drugs & Therapeutics for Pharynx Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Pharynx Squamous Cell Carcinoma

Genetic Tests for Pharynx Squamous Cell Carcinoma

Anatomical Context for Pharynx Squamous Cell Carcinoma

Publications for Pharynx Squamous Cell Carcinoma

Articles related to Pharynx Squamous Cell Carcinoma:

# Title Authors PMID Year
1
Cyclodextrin nanosponge as a temoporfin nanocarrier: Balancing between accumulation and penetration in 3D tumor spheroids. 61
32634570 2020
2
Chrysophanol Regulates Cell Death, Metastasis, and Reactive Oxygen Species Production in Oral Cancer Cell Lines. 61
32595733 2020
3
Stroma-Rich Co-Culture Multicellular Tumor Spheroids as a Tool for Photoactive Drugs Screening. 61
31618880 2019
4
Integrating quantitative morphological and intratumoural textural characteristics in FDG-PET for the prediction of prognosis in pharynx squamous cell carcinoma patients. 61
30245069 2018
5
Increase of phosphatase and tensin homolog by silymarin to inhibit human pharynx squamous cancer. 61
23909904 2013
6
Chromosomal changes in relation to clinical outcome in larynx and pharynx squamous cell carcinoma. 61
16037640 2005
7
[Study on loss of heterozygosity at microsatellite locus in larynx and pharynx squamous cell carcinoma and neck lymph nodes]. 61
15354767 2004
8
Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma. 61
15023835 2004
9
Composite resection with mandibulectomy in the treatment of posterolateral oral cavity and lateral oropharynx squamous cell carcinoma. 61
8214310 1993

Variations for Pharynx Squamous Cell Carcinoma

Expression for Pharynx Squamous Cell Carcinoma

Search GEO for disease gene expression data for Pharynx Squamous Cell Carcinoma.

Pathways for Pharynx Squamous Cell Carcinoma

Pathways related to Pharynx Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.98 RABGGTA PTP4A3

GO Terms for Pharynx Squamous Cell Carcinoma

Cellular components related to Pharynx Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oligosaccharyltransferase complex GO:0008250 8.62 TUSC3 OST4

Biological processes related to Pharynx Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein N-linked glycosylation via asparagine GO:0018279 8.62 TUSC3 OST4

Sources for Pharynx Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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