MCID: PHN001
MIFTS: 25

Phencyclidine Abuse

Categories: Mental diseases

Aliases & Classifications for Phencyclidine Abuse

MalaCards integrated aliases for Phencyclidine Abuse:

Name: Phencyclidine Abuse 12 44 15 73
Pcp Abuse 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5062
MeSH 44 D010623
SNOMED-CT 68 7071007
UMLS 73 C0031391

Summaries for Phencyclidine Abuse

Disease Ontology : 12 A substance abuse that involves the recurring use of phencyclidine (PCP) drugs despite negative consequences.

MalaCards based summary : Phencyclidine Abuse, also known as pcp abuse, is related to depression and head injury. An important gene associated with Phencyclidine Abuse is CALM2 (Calmodulin 2), and among its related pathways/superpathways are Circadian entrainment and fMLP Pathway.

Related Diseases for Phencyclidine Abuse

Diseases related to Phencyclidine Abuse via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 depression 10.2
2 head injury 10.0
3 acneiform dermatitis 9.9 ERBB4 MAP2K7
4 schizophrenia 9.5 APOL1 APOL2 ERBB4 GRIN2B HTR2A

Symptoms & Phenotypes for Phencyclidine Abuse

Drugs & Therapeutics for Phencyclidine Abuse

Search Clinical Trials , NIH Clinical Center for Phencyclidine Abuse

Cochrane evidence based reviews: phencyclidine abuse

Genetic Tests for Phencyclidine Abuse

Anatomical Context for Phencyclidine Abuse

Publications for Phencyclidine Abuse

Articles related to Phencyclidine Abuse:

(show all 40)
# Title Authors Year
1
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. ( 17205118 )
2006
2
A review of PCP abuse trends and perceptions. ( 2502802 )
1989
3
Space-based abstinence: alleviation of withdrawal symptoms in combinative cocaine-phencyclidine abuse. ( 3441016 )
1987
4
Pathological and radiological correlation of subarachnoid hemorrhage in phencyclidine abuse. Case report. ( 3612276 )
1987
5
PCP abuse in New Orleans: a six-year study. ( 3318397 )
1987
6
Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine. ( 3514688 )
1986
7
Phencyclidine (PCP) abuse. A close-up look at a growing problem. ( 2938052 )
1986
8
Diagnosis and treatment of chronic phencyclidine (PCP) abuse. ( 3086736 )
1986
9
Legal issues associated with PCP abuse--the role of the forensic expert. ( 3086737 )
1986
10
Phencyclidine abuse in New Zealand. ( 6591044 )
1984
11
Phencyclidine abuse and depression. ( 6647724 )
1983
12
Intracranial hemorrhage associated with phencyclidine abuse. ( 7097906 )
1982
13
Chronic phencyclidine abuse and physical assault. ( 7149062 )
1982
14
Phencyclidine abuse and crime: a psychiatric perspective. ( 7159767 )
1982
15
Psychiatric and medical syndromes associated with phencyclidine (PCP) abuse. ( 6109037 )
1981
16
Neonatal manifestations of maternal phencyclidine (PCP) abuse. ( 7322687 )
1981
17
Phencyclidine abuse mimicking head injury. ( 7373800 )
1980
18
Phencyclidine abuse in New Orleans: medical, forensic, and laboratory aspects. ( 7347922 )
1980
19
Violence and PCP abuse. ( 7377414 )
1980
20
Epidemiology of PCP abuse: the Midwest perspective. ( 7431417 )
1980
21
Issues for inpatient treatment of chronic PCP abuse. ( 7431426 )
1980
22
PCP abuse: diagnostic and psychopharmacological treatment approaches. ( 7431428 )
1980
23
Chronic phencyclidine (PCP) abuse: a psychiatric perspective. ( 7431430 )
1980
24
A clinical approach to the treatment of phencyclidine (PCP) abuse [proceedings]. ( 7454943 )
1980
25
Chronic phencyclidine (PCP) abuse: a psychiatric perspective--Part I: General aspects and violence [proceedings]. ( 7454944 )
1980
26
Chronic phenycyclidine (PCP) abuse: a psychiatric perspective--Part II: Psychosis [proceedings]. ( 7454945 )
1980
27
Myoglobinuric acute renal failure associated with phencyclidine abuse. ( 18748486 )
1979
28
Violence associated with phencyclidine abuse. ( 507211 )
1979
29
Phencyclidine abuse. Clinical findings and concentrations in biological fluids after nonfatal intoxication. ( 506993 )
1979
30
Case report: symptomatic mania and phencyclidine abuse. ( 758819 )
1979
31
The paradox of phencyclidine (PCP) abuse. ( 426413 )
1979
32
Is phencyclidine (PCP) abuse associated with organic mental impairment?. ( 539570 )
1979
33
Hypertensive crisis and phencyclidine abuse. ( 685417 )
1978
34
Phenomenological aspects of phencyclidine abuse among ethnic groups in Hawaii. ( 101869 )
1978
35
The diagnosis and treatment of the PCP abuse syndrome. ( 101871 )
1978
36
PCP abuse. ( 661052 )
1978
37
Phencyclidine abuse and symptomatic mania. ( 588649 )
1977
38
Notes on Alcoholism and Drug Abuse: Phencyclidine (PCP) Abuse. ( 18748001 )
1977
39
Psychiatric sequelae of phencyclidine abuse. ( 10126 )
1976
40
Out-patient clinical experience in a community drug abuse program with phencyclidine abuse. ( 975755 )
1976

Variations for Phencyclidine Abuse

Expression for Phencyclidine Abuse

Search GEO for disease gene expression data for Phencyclidine Abuse.

Pathways for Phencyclidine Abuse

Pathways related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.8 CALM2 CAMK2B GRIN2B JUN MAP2K7
2
Show member pathways
12.79 CALM2 CAMK2B GRIN2B JUN MAP2K7
3
Show member pathways
12.57 CALM2 CAMK2B ERBB4 JUN MAP2K7
4
Show member pathways
12.52 CALM2 CAMK2B JUN MAP2K7
5
Show member pathways
12.42 CALM2 CAMK2B JUN MAP2K7
6
Show member pathways
12.26 CAMK2B ERBB4 JUN MAP2K7
7
Show member pathways
12.2 CAMK2B ERBB4 JUN MAP2K7
8
Show member pathways
12 CALM2 CAMK2B JUN MAP2K7
9
Show member pathways
11.99 CALM2 CAMK2B GRIN2B
10
Show member pathways
11.94 CALM2 CAMK2B HTR2A JUN MAP2K7
11 11.88 CALM2 JUN MAP2K7
12
Show member pathways
11.86 CALM2 CAMK2B GRIN2B JUN
13 11.78 F2 JUN MAP2K7
14
Show member pathways
11.75 CALM2 CAMK2B JUN
15
Show member pathways
11.73 CALM2 CAMK2B ERBB4 HTR2A
16 11.41 CALM2 CAMK2B GRIN2B
17 11.09 CALM2 ERBB4 JUN MAP2K7
18 11.08 CALM2 GRIN2B
19 11.07 CALM2 CAMK2B
20 11.07 GRIN2B MAP2K7
21
Show member pathways
10.99 CALM2 CAMK2B GRIN2B JUN
22 10.97 CALM2 JUN
23 10.91 CALM2 MAP2K7
24 10.8 APOL1 APOL2

GO Terms for Phencyclidine Abuse

Biological processes related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of JAK-STAT cascade GO:0046427 9.26 ERBB4 F2
2 lipoprotein metabolic process GO:0042157 9.16 APOL1 APOL2
3 lipid transport GO:0006869 9.13 APOL1 APOL2 SCARB1
4 cholesterol metabolic process GO:0008203 8.8 APOL1 APOL2 FDFT1

Molecular functions related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.13 CAMK2B ERBB4 GRIN2B
2 high-density lipoprotein particle binding GO:0008035 8.62 APOL2 SCARB1

Sources for Phencyclidine Abuse

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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