MCID: PHN001
MIFTS: 24

Phencyclidine Abuse

Categories: Mental diseases

Aliases & Classifications for Phencyclidine Abuse

MalaCards integrated aliases for Phencyclidine Abuse:

Name: Phencyclidine Abuse 12 44 15 73
Pcp Abuse 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5062
MeSH 44 D010623
SNOMED-CT 68 7071007
UMLS 73 C0031391

Summaries for Phencyclidine Abuse

Disease Ontology : 12 A substance abuse that involves the recurring use of phencyclidine (PCP) drugs despite negative consequences.

MalaCards based summary : Phencyclidine Abuse, also known as pcp abuse, is related to depression and acneiform dermatitis. An important gene associated with Phencyclidine Abuse is CALM2 (Calmodulin 2), and among its related pathways/superpathways are Circadian entrainment and fMLP Pathway.

Related Diseases for Phencyclidine Abuse

Diseases related to Phencyclidine Abuse via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 depression 10.1
2 acneiform dermatitis 9.9 ERBB4 MAP2K7
3 head injury 9.9
4 schizophrenia 8.1 APOL1 APOL2 ERBB4 GRIN2B HTR2A

Symptoms & Phenotypes for Phencyclidine Abuse

Drugs & Therapeutics for Phencyclidine Abuse

Search Clinical Trials , NIH Clinical Center for Phencyclidine Abuse

Cochrane evidence based reviews: phencyclidine abuse

Genetic Tests for Phencyclidine Abuse

Anatomical Context for Phencyclidine Abuse

Publications for Phencyclidine Abuse

Articles related to Phencyclidine Abuse:

(show all 20)
# Title Authors Year
1
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. ( 17205118 )
2006
2
Space-based abstinence: alleviation of withdrawal symptoms in combinative cocaine-phencyclidine abuse. ( 3441016 )
1987
3
Pathological and radiological correlation of subarachnoid hemorrhage in phencyclidine abuse. Case report. ( 3612276 )
1987
4
Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine. ( 3514688 )
1986
5
Phencyclidine abuse in New Zealand. ( 6591044 )
1984
6
Phencyclidine abuse and depression. ( 6647724 )
1983
7
Intracranial hemorrhage associated with phencyclidine abuse. ( 7097906 )
1982
8
Chronic phencyclidine abuse and physical assault. ( 7149062 )
1982
9
Phencyclidine abuse and crime: a psychiatric perspective. ( 7159767 )
1982
10
Phencyclidine abuse mimicking head injury. ( 7373800 )
1980
11
Phencyclidine abuse in New Orleans: medical, forensic, and laboratory aspects. ( 7347922 )
1980
12
Myoglobinuric acute renal failure associated with phencyclidine abuse. ( 18748486 )
1979
13
Violence associated with phencyclidine abuse. ( 507211 )
1979
14
Phencyclidine abuse. Clinical findings and concentrations in biological fluids after nonfatal intoxication. ( 506993 )
1979
15
Case report: symptomatic mania and phencyclidine abuse. ( 758819 )
1979
16
Hypertensive crisis and phencyclidine abuse. ( 685417 )
1978
17
Phenomenological aspects of phencyclidine abuse among ethnic groups in Hawaii. ( 101869 )
1978
18
Phencyclidine abuse and symptomatic mania. ( 588649 )
1977
19
Psychiatric sequelae of phencyclidine abuse. ( 10126 )
1976
20
Out-patient clinical experience in a community drug abuse program with phencyclidine abuse. ( 975755 )
1976

Variations for Phencyclidine Abuse

Expression for Phencyclidine Abuse

Search GEO for disease gene expression data for Phencyclidine Abuse.

Pathways for Phencyclidine Abuse

Pathways related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.79 CALM2 CAMK2B GRIN2B JUN MAP2K7
2
Show member pathways
12.78 CALM2 CAMK2B GRIN2B JUN MAP2K7
3
Show member pathways
12.54 CALM2 CAMK2B ERBB4 JUN MAP2K7
4
Show member pathways
12.51 CALM2 CAMK2B JUN MAP2K7
5
Show member pathways
12.24 CAMK2B ERBB4 JUN MAP2K7
6
Show member pathways
12.18 CAMK2B ERBB4 JUN MAP2K7
7
Show member pathways
12 CALM2 CAMK2B JUN MAP2K7
8
Show member pathways
11.98 CALM2 CAMK2B GRIN2B
9
Show member pathways
11.94 CALM2 CAMK2B HTR2A JUN MAP2K7
10 11.87 CALM2 JUN MAP2K7
11
Show member pathways
11.86 CALM2 CAMK2B GRIN2B JUN
12 11.76 F2 JUN MAP2K7
13
Show member pathways
11.74 CALM2 CAMK2B JUN
14
Show member pathways
11.73 CALM2 CAMK2B ERBB4 HTR2A
15 11.41 CALM2 CAMK2B GRIN2B
16
Show member pathways
10.99 CALM2 CAMK2B GRIN2B JUN
17 10.97 CALM2 JUN
18 10.9 CALM2 MAP2K7
19 10.79 APOL1 APOL2

GO Terms for Phencyclidine Abuse

Biological processes related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of JAK-STAT cascade GO:0046427 9.26 ERBB4 F2
2 lipoprotein metabolic process GO:0042157 9.16 APOL1 APOL2
3 lipid transport GO:0006869 9.13 APOL1 APOL2 SCARB1
4 cholesterol metabolic process GO:0008203 8.8 APOL1 APOL2 FDFT1

Molecular functions related to Phencyclidine Abuse according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.13 CAMK2B ERBB4 GRIN2B
2 high-density lipoprotein particle binding GO:0008035 8.62 APOL2 SCARB1

Sources for Phencyclidine Abuse

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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