Drugs for Phenylketonuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 42)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Dopamine |
Approved |
Phase 4 |
|
51-61-6, 62-31-7 |
681 |
Synonyms:
(3H)-Dopamine
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-dihydroxyphenyl)ethylamine
2-(3,4-Dihydroxyphenyl)ethylamine
2-benzenediol
3,4 Dihydroxyphenethylamine
3,4-dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-aminoethyl)catechol
4-(2-Aminoethyl)catechol
4-(2-aminoethyl)pyrocatechol
4-(2-aminoethyl)-pyrocatechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)-pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
a-(3,4-Dihydroxyphenyl)-b-aminoethane
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
ASL 279
BIDD:ER0506
Biomol-NT_000001
BPBio1_001123
BSPBio_001932
C03758
CHEBI:18243
CHEMBL59
CID681
cMAP_000036
cMAP_000065
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
dopamine
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopamine hydrochloride
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydrochloride, dopamine
Hydroxytyramin
|
hydroxytyramine
Hydroxytyramine
IDI1_000780
intropin
Intropin
Intropin [*hydrochloride*]
IP 498
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L000232
L-DOPAMINE
LDP
Lopac0_000586
Lopac-H-8502
LS-159
Medopa
Medopa (TN)
m-Hydroxytyramine hydrochloride
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
Spectrum_001012
SPECTRUM1505155
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
ST048774
STK301601
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
|
|
2 |
|
tannic acid |
Approved |
Phase 4 |
|
1401-55-4 |
|
Synonyms:
ácido tánico
Gallotannic acid
|
|
|
3 |
|
Benzocaine |
Approved, Investigational |
Phase 4 |
|
1994-09-7, 94-09-7 |
2337 |
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoate ethyl ester
4-Aminobenzoic acid
4-aminobenzoic acid ethyl ester
4-amino-benzoic acid ethyl ester
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
Acetate, benzocaine
Acetate, Benzocaine
AE-562/40377256
Aethoform
Aethylium paraminobenzoicum
AI3-02081
AKOS000119763
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
AR-1H9065
Baby anbesol
Baby Anbesol
BB_SC-0019
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
benzocaine
Benzocaine
Benzocaine (USP/INN)
Benzocaine [INN:BAN]
Benzocaine acetate
Benzocaine Acetate
Benzocaine formate
Benzocaine Formate
Benzocaine hydrobromide
Benzocaine Hydrobromide
Benzocaine hydrochloride
Benzocaine Hydrochloride
Benzocaine methanesulfonate
Benzocaine Methanesulfonate
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
C07527
CAS-94-09-7
Caswell No. 430A
CHEBI:116735
CHEMBL278172
Chloraseptic
CID2337
D001566
D00552
DB01086
Dermoplast
Diet ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
|
Ethyl 4-aminobenzoic acid
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl PABA
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethyl p-aminophenylcarboxylic acid
ethylaminobenzoate-4
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
ETHYL-P-AMINOBENZOATE
Formate, benzocaine
Formate, Benzocaine
h-4-abz-oet
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, benzocaine
Hydrobromide, Benzocaine
Hydrochloride, benzocaine
Hydrochloride, Benzocaine
I05-0204
Identhesin
IDI1_000932
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
Methanesulfonate, benzocaine
Methanesulfonate, Benzocaine
MLS001331704
MLS002153970
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
nchembio.182-comp4
NINDS_000932
Norcain
Norcaine
Norcainum
NSC 122792
NSC 41531
NSC41531
NSC4688
Oprea1_750694
Oprea1_827402
Orabase-b
Ora-jel
Orthesin
Otocain
Outgro
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
Parathesin
Parathesin (TN)
Parathesine
p-Carbethoxyaniline
p-Ethoxycarboxylic aniline
Prestwick_991
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Slim mint gum
SMR000059025
Solarcaine
Solu H
SPBio_000134
SPBio_002844
Spectrum_000074
SPECTRUM1500139
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
STK043620
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
|
|
4 |
|
Melatonin |
Approved, Nutraceutical, Vet_approved |
Phase 4 |
|
73-31-4 |
896 |
Synonyms:
{N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} acetamide
{N-[2-(5-methoxyindol-3-yl)ethyl]-} acetamide
0E2B08C1-B325-45B1-8939-6F9081EFDFA4
3-(2-Acetamidoethyl)-5-methoxyindole
4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID
5-22-12-00042 (Beilstein Handbook Reference)
5-methoxy-N-acetyltryptamine
5-Methoxy-N-acetyltryptamine
73-31-4
A4039/0172195
AB00053279
AC1L1A9Q
AC1Q4F1W
AC1Q4F1X
Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}
Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}
Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI)
Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI)
AKOS000276269
BAS 01281092
BIDD:ER0618
Bio-0635
BPBio1_000590
BRD-K97530723-001-07-6
BRN 0205542
BSPBio_000536
BSPBio_003006
C01598
CAS-73-31-4
CCRIS 3472
CHEBI:16796
CHEMBL45
ChemDiv2_003916
CID896
Circadin
D008550
D08170
DB01065
DB08189
DivK1c_000353
EINECS 200-797-7
EU-0100787
HMS1380B22
HMS1569K18
HMS1921E04
HMS2089F09
HMS501B15
HSCI1_000400
HSDB 7509
I05-0076
I10-0345
IDI1_000353
IDI1_002631
IN1244
KBio1_000353
KBio2_000665
KBio2_003233
KBio2_005801
KBio3_002226
KBioGR_000591
KBioSS_000665
L001261
Lopac0_000787
Lopac-M-5250
LS-1623
M 5250
M1105
M-1200
M-1250
M5250_SIGMA
Melapure
Mela-T
Melatol
Melatonex
Melatonex, Melatonin
Melatonin
Melatonin (synth.) standard-grade
Melatonin (synth.) ultra-pure
Melatonina
Melatonina (TN)
Melatonine
|
Mélatonine
Melovine
ML1
MLS000859594
MLS001055382
MLS001240204
MolPort-000-737-883
MT6
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)-acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide
N-[2-(5-methoxyindol-3-yl)ethyl]acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]-acetamide
N-acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxytryptamine
N-Acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxy-tryptamine melatonine
Nature'S Harmony
NCGC00015680-01
NCGC00015680-02
NCGC00015680-03
NCGC00015680-06
NCGC00015680-13
NCGC00090727-01
NCGC00090727-02
NCGC00090727-03
NCGC00090727-04
NCGC00090727-05
NCGC00090727-06
NCGC00090727-07
NCGC00090727-08
NCGC00090727-09
NCI60_004378
Night Rest
NINDS_000353
NMR/14327425
NSC 113928
NSC113928
NSC56423
Oprea1_104553
Oprea1_814234
Pineal Hormone
Posidorm
Prestwick_312
Prestwick0_000458
Prestwick1_000458
Prestwick2_000458
Prestwick3_000458
PREVENTION 1 (MELATONIN) (PREVENTION 1)
PREVENTION 2 (MELATONIN)
PREVENTION 3 (MELATONIN)
PREVENTION 4 (MELATONIN)
PREVENTION 5 (MELATONIN)
Regulin
Revital Melatonin
Rx Balance
S1204_Selleck
SDCCGMLS-0065812.P001
SDCCGMLS-0065812.P002
Sleep Right
SMP2_000309
SMR000326666
SPBio_001527
SPBio_002475
Spectrum_000185
SPECTRUM1500690
Spectrum2_001344
Spectrum3_001393
Spectrum4_000066
Spectrum5_001745
STK386880
TNP00300
UNII-JL5DK93RCL
Vivitas
WLN: T56 BMJ D2MV1 GO1
ZINC00057060
|
|
5 |
|
Pharmaceutical Solutions |
|
Phase 4 |
|
|
|
6 |
|
Serotonin |
Investigational, Nutraceutical |
Phase 4 |
|
50-67-9 |
5202 |
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5 Hydroxytryptamine
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
5-Hydroxy-tryptamine
Antemovis
|
DS Substance
Enteramin
Enteramine
Hippophaine
Hydroxytryptamine
Serotonine
sérotonine
thrombocytin
Thrombocytin
thrombotonin
Thrombotonin
|
|
7 |
|
Phenylalanine |
Approved, Investigational, Nutraceutical |
Phase 3 |
|
63-91-2 |
6140 |
Synonyms:
(-)-beta-Phenylalanine
(2S)-2-amino-3-phenylpropanoic acid
(6S)-Tetrahydrofolate
(6S)-Tetrahydrofolic acid
(6S)-THFA
(L)-Phenylalanine
(S)-(-)-Phenylalanine
(S)-2-Amino-3-phenylpropanoate
(S)-2-Amino-3-phenylpropanoic acid
(S)-2-Amino-3-phenylpropionate
(S)-2-Amino-3-phenylpropionic acid
(S)-a-Amino-b-phenylpropionate
(S)-a-Amino-b-phenylpropionic acid
(S)-alpha-Aminobenzenepropanoate
(S)-alpha-Amino-benzenepropanoate
(S)-alpha-Aminobenzenepropanoic acid
(S)-alpha-Amino-benzenepropanoic acid
(S)-alpha-Amino-beta-phenylpropionate
(S)-alpha-Amino-beta-phenylpropionic acid
(S)-alpha-Aminohydrocinnamate
(S)-alpha-Aminohydrocinnamic acid
(S)-Phenylalanine
(S)-Α-amino-β-phenylpropionate
(S)-Α-amino-β-phenylpropionic acid
10549-09-4
1f2p
1F9436B3-8B0D-4AC6-A004-4249B0BDA436
1usi
3-[4-[bis(2-chloroethyl)amino]phenyl]-2-formamidopropanoic acid
303-47-9 OCHRATOXINA
32526-17-3
35849-41-3
3617-44-5
3-Phenylalanine
3-phenyl-l-alanine
3-phenyl-L-alanine
3-Phenyl-L-alanine
5,6,7,8-Tetrahydrofolate
5,6,7,8-Tetrahydrofolic acid
5297-02-9
63-91-2
673-06-3 D-PHENYL)
67675-33-6
78019_FLUKA
78019_SIGMA
801204-11-5
AB1003608
AC1L1LVU
AC1L1XF0
alpha-Aminohydrocinnamate
alpha-Aminohydrocinnamic acid
AmbotzHAA1121
Antibiotic FN 1636
beta-Phenylalanine
beta-Phenyl-alpha-alanine
beta-phenyl-l-alanine
beta-Phenyl-L-alanine
bmse000045
b-Phenyl-L-alanine
C00079
CB 3208
CCRIS 4254
CHEBI:17295
CHEMBL301523
CID37278
CID6140
D00021
DB00120
DB02556
|
EINECS 200-568-1
endophenyl
Endorphenyl
F
FEMA No. 3585
fenilalanina
Fenilalanina
Fenilalanina [Spanish]
H-Phe-OH
HSDB 1825
L-2-Amino-3-phenylpropionate
L-2-Amino-3-phenylpropionic acid
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)-N-formylalanine
L-Antibiotic FN 1636
L-Isomer phenylalanine
L-PHENYL ALANINE (SEE ALSO 22839-47-0, ASPARTAME
L-phenylalanine
L-Phenylalanine
L-Phenylalanine (JP15)
L-Phenylalanine,
L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-N-formyl- (9CI)
L-PHENYLALININE
LS-1515
LS-15879
MolPort-001-757-101
NCGC00013103
NCGC00095047-01
NCGC00095047-02
NCGC00095047-03
NCGC00095047-04
nchembio.185-comp8
nchembio.186-comp89
nchembio.255-comp2
nchembio816-comp8
NCI9959
NCIStruc1_000204
NCIStruc2_000248
N-Formyl-L-p-sarcolysin
N-Formyl-L-sarcolysin
N-Formylmelphalan
NSC 37024
NSC 79477
NSC37024
NSC-9959
P0134
P2126_SIAL
P5482_SIGMA
P8740_SIAL
P8740_SIGMA
phe
Phe
Phenylalamine
phenylalanine
Phenylalanine
Phenyl-alanine
PHENYLALANINE
Phenylalanine (USP/INN)
Phenylalanine (VAN)
Phenylalanine [USAN:INN:JAN]
Phenylalanine, L isomer
Phenylalanine, L-isomer
Phenylalaninum
Phenylalaninum [Latin]
Tetrahydrofolate
THF
UNII-47E5O17Y3R
W358509_ALDRICH
β-phenyl-L-alanine
Î’-phenyl-L-alanine
|
|
8 |
|
Dextrans |
|
Phase 3 |
|
|
|
9 |
|
Plasma Substitutes |
|
Phase 3 |
|
|
|
10 |
|
Anticoagulants |
|
Phase 3 |
|
|
|
11 |
|
Blood Substitutes |
|
Phase 3 |
|
|
|
12 |
|
Hematinics |
|
Phase 1, Phase 2 |
|
|
|
13 |
|
Liver Extracts |
|
Phase 1, Phase 2 |
|
|
|
14 |
|
Moxifloxacin |
Approved, Investigational |
Phase 1 |
|
151096-09-2, 354812-41-2 |
152946 |
Synonyms:
(1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
151096-09-2
186826-86-8
192927-63-2
1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylate
1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid
1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid
AC1L49EP
Actira
Actira (*Hydrochloride*)
Avalox
Avelox
Avelox (*Hydrochloride*)
Avelox I.V.
BAY 12-8039
BAY 12-8039 (*Hydrochloride*)
CCRIS 8690
|
CHEMBL32
CID152946
DB00218
I06-1961
Izilox
LS-141510
MFX
moxifloxacin
Moxifloxacin
Moxifloxacin [INN:BAN]
Moxifloxacin HCl
Moxifloxacin hydrochloride
Moxifloxacino
MXF
MXFX
Octegra
Proflox
UNII-U188XYD42P
Vigamox
|
|
15 |
|
Nitric Oxide |
Approved |
Phase 1 |
|
10102-43-9 |
145068 |
Synonyms:
(.)NO
(NO)(.)
[NO]
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous nitrate vasodilator
Endogenous Nitrate Vasodilator
Endothelium-derived nitric oxide
Endothelium-Derived Nitric Oxide
endothelium-derived relaxing factor
Endothelium-derived relaxing factor
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, mononitrogen
Monoxide, Mononitrogen
Monoxide, nitrogen
Monoxide, Nitrogen
monoxido de nitrogeno
Monoxido de nitrogeno
Monóxido de nitrógeno
monoxyde d'azote
Monoxyde d'azote
Nitrate vasodilator, endogenous
Nitrate Vasodilator, Endogenous
nitric oxide
|
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, endothelium derived
Nitric Oxide, Endothelium Derived
Nitric oxide, endothelium-derived
Nitric Oxide, Endothelium-Derived
NITRIC-OXIDE
nitrogen monooxide
Nitrogen monooxide
nitrogen monoxide
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
nitrosyl
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
NO
NO(.)
OHM 11771
Oxide, nitric
Oxide, Nitric
oxido de nitrogeno(II)
Oxido de nitrogeno(II)
óxido de nitrógeno(II)
oxido nitrico
Oxido nitrico
óxido nítrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, endogenous nitrate
Vasodilator, Endogenous Nitrate
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16 |
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Anti-Infective Agents |
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Phase 1 |
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17 |
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Anti-Bacterial Agents |
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Phase 1 |
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18 |
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Norgestimate, ethinyl estradiol drug combination |
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Phase 1 |
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|
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19 |
|
Coal tar |
Approved |
|
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8007-45-2 |
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Synonyms:
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20 |
|
Methylcobalamin |
Approved, Investigational |
|
|
13422-55-4 |
|
Synonyms:
Co-methylcobalamin
CO-METHYLCOBALAMIN
MeCbl
Mecobalamin
Mecobalamina
|
Mecobalaminum
Methyl vitamin B12
Methyl(III)cobalamin
Methylcob(III)alamin
Methylcobalamin
|
|
21 |
|
Hydroxocobalamin |
Approved |
|
|
13422-51-0 |
11953898 15589840 |
Synonyms:
13422-51-0
22465-48-1
78091-12-0
8017-22-9
a-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
Acti-B12
alpha Cobione
alpha-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
AlphaRedisol
AlphaRedisol (TN)
Axion
Axlon
Benzimidazolyl ribofuranosyl phosphate deriv.
C08230
C62H85CoN13O15P
CHEBI:27786
CHEMBL1200742
CHEMBL235822
CID11622291
CID11953898
CID5460373
CID6433575
CID6474319
Ciplamin H
Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-hydroxocobamide
Cobalex
Cobalin H
Cobinamide dihydroxide dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole inner salt
Cobinamide, Co-hydroxy-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'- ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Cobinamide, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Codroxomin
Cyanokit
Cyanokit (TN)
D01027
DB00200
Depogamma
Docclan
Docelan
Docelvita
Docevita
Droxomin
Ducobee hy
Ducobee-Hy
Duradoce
Duralta-12
EINECS 236-533-2
Hidroxocobalamina
Hidroxocobalamina [INN-Spanish]
HSDB 3342
Hydro Cobex
|
Hydrobamine
Hydrocobalamin
Hydrogrisevit
Hydrovit
Hydroxocobalamin
Hydroxo-cobalamin
HYDROXOCOBALAMIN
Hydroxocobalamin (JAN/USP/INN)
Hydroxocobalamin [USAN:INN:BAN:JAN]
Hydroxocobalamin acetate
Hydroxocobalamin anhydrous
Hydroxocobalamin monohydrochloride
Hydroxocobalamin Vitamin B12
Hydroxocobalamin(alkaline soln.), OH- replaces CN- in Cyanocobalamin)
Hydroxocobalaminacetat
Hydroxocobalamine
Hydroxocobalamine [INN-French]
Hydroxocobalaminum
Hydroxocobalaminum [INN-Latin]
Hydroxocobalaminum anhydrous
Hydroxocobemine
Hydroxomin
Hydroxy Cobal
Hydroxy vitamin B12
Hydroxycob(lll)alamin
Hydroxycobalamin
Hydroxycobalamine
Hyxobamine
Idrogrisevit
Idrossocobalamina
Idrossocobalamina [DCIT]
LS-54607
Lyovit-H
Neo-Betalin 12
Neo-cytamen
Neo-macrabin
Neo-rojamin
Ohb12
OH-Cbl
OH-CBL
OH-Duphar
Oxobemin
Oxolamine (arcum)
Primabalt RP
Redisol-H
S1668_Selleck
Sytobex-H
UNII-Q40X8H422O
Vibeden
Vitadurin
Vitamin B(sub 12a)
Vitamin B12a
vitamin B-12b
Vitamin b-12b
Vitamin B12b
Vitamin B-12b
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22 |
|
Cyanocobalamin |
Approved, Nutraceutical |
|
|
68-19-9 |
44176380 |
Synonyms:
Anacobin
Bedoz
Berocca PN
Berubigen
Betalin 12
Betalin 12 crystalline
Betaline-12
Betolvex
Bevidox
Bevidox concentrate
Biocobalamine
Byladoce
Cabadon m
Cernevit-12
Cianocobalamina
Cobadoce forte
Cobalin
Cobavite
Cobex
Cobolin-M
Copharvit 5000
Covit
Crystamin
Crystamine
Crysti-12
Crystimin
Crystwel
Cyano-b12
Cyanobalamin concentrate
Cyanocob(III)alamin
Cyanocobalamin
Cyanocobalamin (JP15/usp)
Cyanocobalamin Co 57 Schilling Test Kit
Cyanocobalamine
Cyanocobalaminum
Cyanocobalmin
Cyanoject
Cycobemin
Cycolamin
Cykobemin
Cykobeminet
Cyomin
Cyredin
Cytacon
Cytamen
Cytobion
Depinar
Dicopac
Dicopac Kit
Dimethylbenzimidazoylcobamide
Distivit
Docemine
Docibin
Docivit
Dodecabee
Dodecavite
Dodex
Duodecibin
Embiol
Emociclina
Eritrone
Erycytol
|
Erythrotin
Euhaemon
Extrinsic factor
Factor II
Fermin
Fresmin
Hemomin
Hepagon
Hepavis
Hepcovite
Hylugel plus
Infuvite Pediatric
Lactobacillus lactis dorner factor
M.V.I. Pediatric
Macrabin
Megabion
Megalovel
Milbedoce
Millevit
Nagravon
Nascobal
Neuroforte-R
Normocytin
Novidroxin
Pernaemon
Pernaevit
Pernipuron
Plecyamin
Poyamin
Primabalt
Rebramin
Redamina
Redisol
Rhodacryst
Rubesol
Rubivite
Rubramin
Rubramin PC
Rubratope-57 Kit
Rubratope-60 Kit
Rubripca
Rubrocitol
Ruvite
Shovite
Sytobex
Vibal
Vibalt
Vibisone
Virubra
Vitabee 12
Vitamin b12
Vitamin B12
Vitamin b12 complex
Vitamin B12 complex
Vitamin B12 NOS
Vitamin b12 preparation
vitamine b12
Vitaped
Vitarubin
Vita-rubra
Vitral
Vi-Twel
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23 |
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Tyrosine |
Approved, Investigational, Nutraceutical |
|
|
60-18-4 |
6057 |
Synonyms:
(-)-a-Amino-p-hydroxyhydrocinnamate
(-)-a-Amino-p-hydroxyhydrocinnamic acid
(-)-alpha-Amino-p-hydroxyhydrocinnamate
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid
(-)-Α-amino-p-hydroxyhydrocinnamate
(−)-α-amino-p-hydroxyhydrocinnamic acid
(-)-Α-amino-p-hydroxyhydrocinnamic acid
(2S)-2-Amino-3-(4-hydroxyphenyl)propanoate
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
(2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid
(S)-(-)-Tyrosine
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid
(S)-2-Amino-3-(p-hydroxyphenyl)propionate
(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid
(S)-3-(p-Hydroxyphenyl)alanine
(S)-a-Amino-4-hydroxybenzenepropanoate
(S)-a-Amino-4-hydroxy-benzenepropanoate
(S)-a-Amino-4-hydroxybenzenepropanoic acid
(S)-a-Amino-4-hydroxy-benzenepropanoic acid
(S)-alpha-Amino-4-hydroxybenzenepropanoate
(S)-alpha-Amino-4-hydroxy-benzenepropanoate
(S)-alpha-amino-4-Hydroxybenzenepropanoic acid
(S)-alpha-Amino-4-hydroxybenzenepropanoic acid
(S)-alpha-Amino-4-hydroxy-benzenepropanoic acid
(S)-Tyrosine
(S)-Α-amino-4-hydroxybenzenepropanoate
(S)-α-amino-4-hydroxybenzenepropanoic acid
(S)-Α-amino-4-hydroxybenzenepropanoic acid
140-43-2
1991-85-1
25619-78-7
2-Amino-3-(4-hydroxyphen yl)-2-amino-3-(4-hydroxyphenyl)-propanoate
2-Amino-3-(4-hydroxyphen yl)-2-amino-3-(4-hydroxyphenyl)-propanoic acid
2-Amino-3-(p-hydroxyphenyl)propionic acid
2csm
3-(4-Hydroxyphenyl)-L-alanine
3-(p-Hydroxyphenyl)alanine
46209-14-7
4-hydroxy-L-phenylalanine
4-Hydroxy-L-phenylalanine
4ts1
55520-40-6
60-18-4
93829_FLUKA
93829_SIGMA
AB1002647
AC-11295
AC1L1LPI
AC1Q4U7L
AC1Q4U7M
AI3-09055
alpha-Amino-beta-(4-hydroxyphenyl)propionic acid
AR-1J3457
BB_NC-1194
Benzenepropanoate
Benzenepropanoic acid
beta-(p-Hydroxyphenyl)alanine
bmse000051
C00082
CHEBI:17895
CHEMBL925
CID6057
D00022
DB00135
|
DB03839
DD69927C-C6A8-4BC6-8E9A-0AB423B176E7
DTY
EINECS 200-460-4
FEMA No. 3736
Free-Form L-Tyrosine
HSDB 2003
H-Tyr-OH
L Tyrosine
L-(-)-Tyrosine
L-2-Amino-3-p-hydroxyphenylpropanoic acid
L-p-Tyrosine
LS-2336
L-Tyrosin
L-tyrosine
L-Tyrosine (9CI)
L-Tyrosine (JAN)
L-Tyrosine hydrochloride
L-Tyrosine, homopolymer
L-Tyrosine, monomer
Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs
Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide
Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide, <3 kd fraction
Melanin synthesized from Tyr substrate catalyzed by tyrosinase, brominated with N-bromosuccinimide
Melanin synthesized from Tyr substrate catalyzed by tyrosinase, sulfonated using sulfur trioxide/DMF complex for 1.5-7 hours
MolPort-001-792-016
NCGC00159350-02
NCGC00159350-03
nchembio.105-comp1
nchembio.121-comp7
nchembio.186-comp84
nchembio.284-comp7
nchembio816-comp11
NSC 82624
Para tyrosine
Para-tyrosine
p-Tyrosine
Rxosine
T0550
T3754_SIAL
T4321_SIAL
T4321_SIGMA
T8566_SIGMA
tirosina
Tirosina
Tirosina [Spanish]
tyr
Tyr
TYR NH3+ COOH
tyrosine
Tyrosine
TYROSINE
Tyrosine (USP/INN)
Tyrosine (VAN)
Tyrosine [USAN:INN]
Tyrosine Power
Tyrosine, L- (8CI)
Tyrosine, L isomer
Tyrosine, L-isomer
Tyrosinum
Tyrosinum [Latin]
UNII-42HK56048U
W373605_ALDRICH
Y
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24 |
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arachidonic acid |
Experimental |
|
|
506-32-1 |
444899 |
Synonyms:
(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoate
(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoate
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid
(5Z,8Z,11Z,14Z)-Icosatetraenoate
(5Z,8Z,11Z,14Z)-Icosatetraenoic acid
(all-Z)-5,8,11,14-Eicosatetraenoate
(all-Z)-5,8,11,14-Eicosatetraenoic acid
5,8,11,14-all-cis-Eicosatetraenoate
5,8,11,14-all-cis-Eicosatetraenoic acid
5,8,11,14-Eicosatetraenoate
5,8,11,14-Eicosatetraenoic acid
5-cis,8-cis,11-cis,14-cis-Eicosatetraenoate
5-cis,8-cis,11-cis,14-cis-Eicosatetraenoic acid
5Z,8Z,11Z,14Z-Eicosatetraenoate
5Z,8Z,11Z,14Z-Eicosatetraenoic acid
AA
all-cis-5,8,11,14-Eicosatetraenoate
all-cis-5,8,11,14-Eicosatetraenoic acid
ARA
Arachidonate
Arachidonate, sodium
Arachidonic acid, (all-Z)-isomer, 1-(14)C-labeled
|
Arachidonic acid, (all-Z)-isomer, 3H-labeled
Arachidonic acid, ammonium salt, (all-Z)-isomer
Arachidonic acid, cerium salt, (all-Z)-isomer
Arachidonic acid, cesium salt, (all-Z)-isomer
Arachidonic acid, lithium salt, (all-Z)-isomer
Arachidonic acid, potassium salt, (all-Z)-isomer
Arachidonic acid, sodium salt
Arachidonic acid, sodium salt, (all-Z)-isomer
Arachidonic acid, zinc salt, (all-Z)-isomer
Arachidonsaeure
cis-5,8,11,14-Eicosatetraenoate
cis-5,8,11,14-Eicosatetraenoic acid
cis-D5,8,11,14-Eicosatetraenoate
cis-D5,8,11,14-Eicosatetraenoic acid
cis-delta(5,8,11,14)-Eicosatetraenoate
cis-Delta(5,8,11,14)-Eicosatetraenoic acid
cis-Δ(5,8,11,14)-eicosatetraenoate
cis-Δ(5,8,11,14)-eicosatetraenoic acid
FA(20:4(5Z,8Z,11Z,14Z))
FA(20:4n6)
Immunocytophyte
Sodium arachidonate
Vitamin F
|
|
25 |
|
Cobalamin |
Experimental |
|
|
13408-78-1 |
6857388 |
Synonyms:
5,6-Dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-a-D-ribofuranosylbenzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosylbenzimidazole
a-(5,6-Dimethylbenzimidazolyl)cobamide
alpha-(5,6-Dimethylbenzimidazolyl)cobamide
b 12, Vitamin
b12, Vitamin
Cbl
Cob(III)alamin
Cobalamin (III)
Cobalamin(1+)
Cobalamin(III)
Cobalamine
|
Cobalamins
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
Cyanocobalamin
Eritron
Hydroxomin
Rubivite
Rubratope-57
Rubratope-60
Ruvite
Vitamin b 12
Vitamin b12
Α-(5,6-dimethylbenzimidazolyl)cobamide
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26 |
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Sunflower |
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27 |
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Fluorodeoxyglucose F18 |
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28 |
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Soy Bean |
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29 |
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Whey Protein |
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30 |
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Antioxidants |
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31 |
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Keratolytic Agents |
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32 |
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Dermatologic Agents |
|
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33 |
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Omega 3 Fatty Acid |
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34 |
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Nutrients |
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35 |
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Vitamins |
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36 |
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Trace Elements |
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37 |
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Micronutrients |
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38 |
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Vitamin B Complex |
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39 |
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Vitamin B 12 |
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40 |
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Vitamin B12 |
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41 |
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Caseins |
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42 |
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lysine |
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Interventional clinical trials:
(show top 50)
(show all 116)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
ENDURE: A Phase IV, Prospective, Open-label, Uncontrolled, Multi-centre Cohort Trial to Assess the Responsiveness of Subjects With Phenylketonuria (PKU) to Treatment With Kuvan® 20 mg/kg/Day for 28 Days |
Completed |
NCT01082328 |
Phase 4 |
Kuvan® |
2 |
Pilot Study to Evaluate Melatonin Secretion as a Marker of Decreased Serotonin in Individuals With PKU: Evaluation of the CNS Effects of Tetrahydrobiopterin |
Completed |
NCT01617070 |
Phase 4 |
Kuvan |
3 |
PICO: Phenylalanine and Its Impact on Cognition - Impact of Phenylalanine on Cognitive, Cerebral and Neurometabolic Parameters in Adult Patients With Phenylketonuria |
Recruiting |
NCT03788343 |
Phase 4 |
Placebo |
4 |
The Effectiveness of High-Dose Synthetic BH4 (Saproterin Dihydrochloride or "Kuvan") in Amish PKU Patients |
Recruiting |
NCT02677870 |
Phase 4 |
saproterin dihydrochloride |
5 |
A Phase 4 Open-Label, Single-Cohort Study of the Long-Term Neurocognitive Outcomes in 4 to 5 Year-Old Children With Phenylketonuria Treated With Sapropterin Dihydrochloride (Kuvan®) for 7 Years |
Active, not recruiting |
NCT01965912 |
Phase 4 |
Kuvan® |
6 |
To Evaluate BH4 Responsiveness in PAH Deficiency PKU Patients Who Failed to Achieve 30% Blood Phe Reduction Within 24-hour BH4 Loading Test by Extending the Period of BH4 Response Test: A Pilot Study in Taiwan |
Not yet recruiting |
NCT04227080 |
Phase 4 |
BH4 |
7 |
A Phase 3, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels |
Completed |
NCT00225615 |
Phase 3 |
sapropterin dihydrochloride |
8 |
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Phenoptinâ„¢ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels |
Completed |
NCT00104247 |
Phase 3 |
sapropterin dihydrochloride, 6R-BH4, tetrahydrobiopterin |
9 |
A Phase 3, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet |
Completed |
NCT00272792 |
Phase 3 |
Sapropterin Dihydrochloride;Placebo |
10 |
A Phase IIIb, Multicentre, Open-Label, Randomized, Controlled Study of the Efficacy, Safety, and Population Pharmacokinetics of Sapropterin Dihydrochloride (Kuvan®) in Phenylketonuria (PKU) Patients <4 Years Old. |
Completed |
NCT01376908 |
Phase 3 |
Kuvan® |
11 |
A Double-blind, Placebo-controlled, Randomized Study to Evaluate the Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Subjects With Phenylketonuria |
Completed |
NCT01114737 |
Phase 3 |
Sapropterin dihydrochloride;Placebo |
12 |
A Phase 3b, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With Phenylketonuria Who Participated in Protocols PKU-004 or PKU-006 |
Completed |
NCT00332189 |
Phase 3 |
sapropterin dihydrochloride |
13 |
A Phase III Non-comparative Open-label Clinical Study to Evaluate the Response to and Safety of Kuvan (Sapropterin Dihydrochloride) After 6 Weeks of Treatment in Patients of 4 to 18 Years of Age With Phenylketonuria Who Have Elevated Blood Phenylalanine Levels |
Completed |
NCT01732471 |
Phase 3 |
Kuvan® |
14 |
A Four-Part, Phase 3, Randomized, Double-Blind, Placebo- Controlled, Four-Arm, Discontinuation Study to Evaluate the Efficacy and Safety of Subcutaneous Injections of BMN 165 Self-Administered by Adults With Phenylketonuria (PKU) |
Completed |
NCT01889862 |
Phase 3 |
BMN165 20mg/day;BMN165 40mg/day;Placebo |
15 |
A Phase 3b Open-Label Study to Evaluate the Effect of Kuvan® on Neurocognitive Function, Maintenance of Blood Phenylalanine Concentrations, Safety, and Population Pharmacokinetics in Young Children With Phenylketonuria |
Completed |
NCT00838435 |
Phase 3 |
sapropterin dihydrochloride |
16 |
An Open-label Extension Study to Evaluate the Safety and Efficacy of Subcutaneous Injections of Pegvaliase (> 40 mg/Day Dose) in Adults With Phenylketonuria |
Completed |
NCT03694353 |
Phase 3 |
Pegvaliase |
17 |
A Phase 3, Open-Label, Randomized, Multi-Center Study to Assess the Safety & Tolerability of an Induction, Titration, and Maintenance Dose Regimen of BMN 165 Self Administered by Adults With PKU Not Previously Treated With BMN 165 |
Completed |
NCT01819727 |
Phase 3 |
BMN 165 |
18 |
Double-Blind, Placebo Controlled, Multicentre Study With an Open Label Extension to Evaluate the Efficacy and Safety of Tetrahydrobiopterin (BH4) in Children and Adolescents With Hyperphenylalaninemia Caused by Phenylalanine Hydroxylase Deficiency |
Terminated |
NCT00432822 |
Phase 2, Phase 3 |
tetrahydrobiopterin (BH4) |
19 |
A Phase 1/2, Open-Label, Randomized Parallel Arm, Intra-patient Dose Escalation Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of CNSA-001(Sepiapterin) in Primary Tetrahydrobiopterin Deficient Patients With Hyperphenylalaninemia |
Completed |
NCT03519711 |
Phase 1, Phase 2 |
CNSA-001 |
20 |
Phase 2, Multicenter, Open Label Study of Phenoptin in Subjects With Hyperphenylalaninemia Due to Primary BH4 Deficiency |
Completed |
NCT00355264 |
Phase 2 |
Phenoptin |
21 |
A Phase 2, Multicenter, Open-Label Study to Evaluate the Response to and Safety of an 8-Day Course of Phenoptinâ„¢ Treatment in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels |
Completed |
NCT00104260 |
Phase 2 |
sapropterin dihydrochloride |
22 |
A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics |
Completed |
NCT03516487 |
Phase 1, Phase 2 |
SYNB1618;Placebo |
23 |
A Phase 2, Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Subcutaneous Dose Levels of rAvPAL-PEG Administered Daily in Subjects With Phenylketonuria |
Completed |
NCT01212744 |
Phase 2 |
rAvPAL-PEG |
24 |
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response |
Completed |
NCT00841100 |
Phase 2 |
Kuvan |
25 |
Study of the Response of Tetrahydrobiopterin on S-Phenylalanine in Patients With PKU Housing the Y414C Mutation |
Completed |
NCT00260000 |
Phase 2 |
5,6,7,8-tetrahydrobiopterin |
26 |
Phase 2, Open-Label Dose-Finding Study to Evaluate the Safety, Efficacy, and Tolerability of Multiple Subcutaneous (SC) Doses of rAvPAL-PEG in Subjects With PKU |
Completed |
NCT00925054 |
Phase 2 |
rAvPAL-PEG 0.001 mg/kg;rAvPAL-PEG 0.003 mg/kg;rAvPAL-PEG 0.01 mg/kg;rAvPAL-PEG 0.03 mg/kg;rAvPAL-PEG 0.1 mg/kg |
27 |
Long-term Extension of a Phase 2, Open-Label Dose-Finding Study to Evaluate the Safety, Efficacy, and Tolerability of Multiple Subcutaneous Doses of rAvPAL-PEG in Subjects With PKU |
Completed |
NCT00924703 |
Phase 2 |
rAvPAL-PEG |
28 |
A Phase II, Multi-center, Open-label, Dose-finding Study to Evaluate Safety, Efficacy and Tolerability of Subcutaneously (SC) Administered rAvPAL-PEG in Patients With PKU for 24 Weeks |
Completed |
NCT01560286 |
Phase 2 |
|
29 |
Hepatocyte Transplantation for Phenylketonuria |
Recruiting |
NCT01465100 |
Phase 1, Phase 2 |
Immunosuppression |
30 |
A Phase 1/2 Open-Label, Randomized, Concurrently-Controlled, Dose Escalation Study to Evaluate the Safety and Efficacy of HMI-102 in Adult PKU Subjects With PAH Deficiency |
Recruiting |
NCT03952156 |
Phase 1, Phase 2 |
|
31 |
An Open-label Study of the Efficacy and Safety of SYNB1618 in Patients With Phenylketonuria (SynPheny-1) |
Recruiting |
NCT04534842 |
Phase 2 |
SYNB1618 |
32 |
A Phase 1/2 Open-Label, Dose Escalation Study to Determine the Safety and Efficacy of BMN 307, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Phenylalanine Hydroxylase in Subjects With Phenylketonuria |
Recruiting |
NCT04480567 |
Phase 1, Phase 2 |
BMN 307 |
33 |
A Multicenter, Double-Blind, Placebo-Controlled, Randomized, 2-Arm Phase IIa Pilot Trial Assessing the Effect of Sapropterin on Cognitive Abilities in Young Adults With Phenylketonuria |
Terminated |
NCT01977820 |
Phase 2 |
Sapropterin;Placebo |
34 |
The Ability of Kuvan® (Sapropterin Dihydrochloride) to Prevent Meal-induced Lipid Peroxidation and Endothelial Dysfunction in Patients With Phenylketonuria: a Pilot Study |
Terminated |
NCT01395394 |
Phase 2 |
Kuvan |
35 |
A Phase I, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Subcutaneous Doses of rAvPAL-PEG in Subjects With Phenylketonuria |
Completed |
NCT00634660 |
Phase 1 |
rAvPAL-PEG |
36 |
A Phase 1, Multi-center, Randomized, Double-blind, Placebo-controlled, Cross-over Study to Evaluate the Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of a Single Oral Dose of CDX-6114 in Patients With Phenylketonuria (PKU). |
Completed |
NCT04085666 |
Phase 1 |
CDX 6114 |
37 |
A Phase 1, Randomized, Placebo- and Active-controlled Crossover Study to Evaluate the Effects of Sapropterin Dihydrochloride Oral Administration on QTc Intervals in Healthy Adult Subjects |
Completed |
NCT00789568 |
Phase 1 |
sapropterin dihydrochloride;Moxifloxacin |
38 |
A Phase 1b Open-Label Single Dose Safety, Tolerability, and Pharmacokinetics Study of RTX-134 in Adults With Phenylketonuria |
Active, not recruiting |
NCT04110496 |
Phase 1 |
RTX-134 |
39 |
Role of Nitric Oxide Coupling in Muscle Dysfunction With COPD |
Not yet recruiting |
NCT04014712 |
Phase 1 |
Tetrahydrobiopterin;Placebo oral tablet |
40 |
Response to Phenylketonuria to Tetrahydrobiopterin (BH4) |
Terminated |
NCT00244218 |
Phase 1 |
tetrahydrobiopterin (BH4) |
41 |
A Phase 1, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of CDX 6114 After Multiple Ascending Oral Dose Administration to Patients With Phenylketonuria (PKU). |
Withdrawn |
NCT04256655 |
Phase 1 |
cohort 1 0.225g;Cohort 2 0.75g;Cohort 3 2.25 g |
42 |
- Contribution of Diet Induced Thermogenesis (DIT) and Fat Oxidation to Body Fatness and Body Composition of Patients With Phenylketonuria - Contribution of Physical Activity Energy Expenditure and Energy Intake to Body Fatness and Body Composition of Patients With Phenylketonuria |
Unknown status |
NCT03309345 |
|
|
43 |
Sapropterin Expanded Access Program |
Approved for marketing |
NCT00484991 |
|
Sapropterin dihydrochloride |
44 |
Biological Variation of Phenylalanine in Patients With Hyperphenylalaninemia |
Completed |
NCT01869972 |
|
|
45 |
Effects of Sapropterin on Brain and Cognition in Individuals With Phenylketonuria |
Completed |
NCT00730080 |
|
Sapropterin (Kuvan) |
46 |
Study of a Phenylalanine Restricted Diet During Pregnancy to Prevent Symptoms in Offspring of Patients With Phenylketonuria |
Completed |
NCT00006142 |
|
|
47 |
Quantitative Requirements of Docosahexaenoic Acid for Neural Function in Children With Phenylketonuria |
Completed |
NCT00909012 |
|
|
48 |
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression in PKU "Nonresponders" to Kuvan® (Sapropterin Dihydrochloride) |
Completed |
NCT01274026 |
|
sapropterin dihydrochloride |
49 |
5-year Follow-up of the Comparison of Life and Physical Health in Adult Patients With PKU and Healthy Age Matched Controls |
Completed |
NCT01096758 |
|
|
50 |
Nutrition Status of Adult and Adolescent Patients With Classical Phenylketonuria (PKU) and Hyperphenylalaninemia |
Completed |
NCT01879995 |
|
|
Cell-based therapeutics:
Data from LifeMap, the Embryonic Development and Stem Cells Database
Stem-cell-based therapeutic approaches for Phenylketonuria:
Embryonic/Adult Cultured Cells Related to Phenylketonuria:
Cochrane evidence based reviews: phenylketonurias
|