MCID: PHN016
MIFTS: 14

Phenytoin Allergy

Categories: Immune diseases

Aliases & Classifications for Phenytoin Allergy

MalaCards integrated aliases for Phenytoin Allergy:

Name: Phenytoin Allergy 12 15
Dilantin Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040012
UMLS 71 C0570789

Summaries for Phenytoin Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger phenytoin.

MalaCards based summary : Phenytoin Allergy, also known as dilantin allergy, is related to multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly and exanthem. An important gene associated with Phenytoin Allergy is TBXA2R (Thromboxane A2 Receptor), and among its related pathways/superpathways are Calcium signaling pathway and Eicosanoid ligand-binding receptors. Affiliated tissues include testes.

Related Diseases for Phenytoin Allergy

Diseases related to Phenytoin Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
2 exanthem 9.9
3 allergic hypersensitivity disease 9.9

Symptoms & Phenotypes for Phenytoin Allergy

Drugs & Therapeutics for Phenytoin Allergy

Search Clinical Trials , NIH Clinical Center for Phenytoin Allergy

Genetic Tests for Phenytoin Allergy

Anatomical Context for Phenytoin Allergy

MalaCards organs/tissues related to Phenytoin Allergy:

40
Testes

Publications for Phenytoin Allergy

Articles related to Phenytoin Allergy:

# Title Authors PMID Year
1
Spontaneous complete regression of hypothalamic pilocytic astrocytoma after partial resection in a child, complicated with Stevens-Johnson syndrome: a case report and literature review. 61
26662551 2016
2
Phenytoin hypersensitivity syndrome with positive patch test. A possible cross-reactivity with amitriptyline. 61
9684195 1998
3
Allergic reactions to phenytoin in a general hospital in Singapore. 61
9177818 1996
4
Seasonal incidence of phenytoin allergy unrelated to plasma levels. 61
3977636 1985

Variations for Phenytoin Allergy

Expression for Phenytoin Allergy

Search GEO for disease gene expression data for Phenytoin Allergy.

Pathways for Phenytoin Allergy

Pathways related to Phenytoin Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.25 TBXA2R CYSLTR1
2
Show member pathways
10.3 TBXA2R CYSLTR1

GO Terms for Phenytoin Allergy

Biological processes related to Phenytoin Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 8.62 TBXA2R CYSLTR1

Sources for Phenytoin Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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