MCID: PHL003
MIFTS: 29

Phlebotomus Fever

Categories: Infectious diseases

Aliases & Classifications for Phlebotomus Fever

MalaCards integrated aliases for Phlebotomus Fever:

Name: Phlebotomus Fever 12 44 15 17 72
Sandfly Fever 12 33
Sandfly-Borne Phleboviral Disease 12
Sandfly-Borne Bunyavirus Fever 12
Sandfly-Borne Arboviral Fever 12
Pappataci Fever 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11360
ICD9CM 35 066.0
MeSH 44 D010217
SNOMED-CT 68 33670001
ICD10 33 A93.1
UMLS 72 C0030372

Summaries for Phlebotomus Fever

Disease Ontology : 12 A viral infectious disease that results in infection, has material basis in Sandfly fever Naples virus, or has material basis in Sandfly fever sicilian virus, which are transmitted by Phlebotomus papatasi sandfly. The infection has symptom fever, has symptom severe frontal headaches, has symptom muscle ache, has symptom joint aches, has symptom flushing of the face, and has symptom tachycardia.

MalaCards based summary : Phlebotomus Fever, also known as sandfly fever, is related to meningoencephalitis and west nile virus. An important gene associated with Phlebotomus Fever is CD40LG (CD40 Ligand), and among its related pathways/superpathways is Type II interferon signaling (IFNG). Affiliated tissues include testes, kidney and neutrophil.

Wikipedia : 75 Pappataci fever (also known as Phlebotomus fever and, somewhat confusingly, sandfly fever and three-day... more...

Related Diseases for Phlebotomus Fever

Diseases related to Phlebotomus Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 meningoencephalitis 10.4
2 west nile virus 10.3
3 rift valley fever 10.3
4 coccidioidomycosis 10.3
5 exanthem 10.2
6 thrombocytopenia 10.2
7 west nile encephalitis 10.2
8 west nile fever 10.2
9 viral encephalitis 10.2
10 visceral leishmaniasis 10.2
11 viral infectious disease 10.2
12 q fever 10.2
13 aseptic meningitis 10.2
14 iridocyclitis 10.2
15 anterior uveitis 10.2
16 kala-azar 1 10.1
17 tick-borne encephalitis 10.1
18 neutropenia 10.1
19 tularemia 10.1
20 plague 10.1
21 lymphopenia 10.1
22 leishmaniasis 10.1
23 cutaneous leishmaniasis 10.1
24 meningitis 10.1
25 encephalitis 10.1
26 47,xyy 10.1
27 immunoglobulin switch sequences 10.1
28 triiodothyronine receptor auxiliary protein 10.1
29 yemenite deaf-blind hypopigmentation syndrome 10.1
30 branchiootic syndrome 1 10.1
31 malaria 10.1
32 neuroretinitis 10.1
33 viral meningitis 10.1
34 crimean-congo hemorrhagic fever 10.1
35 diarrhea 10.1
36 viral hepatitis 10.1
37 hyperinsulinism 10.1
38 retinitis 10.1
39 conjunctivitis 10.1
40 stomatitis 10.1
41 back pain 10.1
42 headache 10.1
43 meningitis and encephalitis 10.1
44 pneumocystosis 9.6 MT-CYB CD40LG

Graphical network of the top 20 diseases related to Phlebotomus Fever:



Diseases related to Phlebotomus Fever

Symptoms & Phenotypes for Phlebotomus Fever

Drugs & Therapeutics for Phlebotomus Fever

Search Clinical Trials , NIH Clinical Center for Phlebotomus Fever

Cochrane evidence based reviews: phlebotomus fever

Genetic Tests for Phlebotomus Fever

Anatomical Context for Phlebotomus Fever

MalaCards organs/tissues related to Phlebotomus Fever:

41
Testes, Kidney, Neutrophil, Brain, Skin, T Cells

Publications for Phlebotomus Fever

Articles related to Phlebotomus Fever:

(show top 50) (show all 264)
# Title Authors PMID Year
1
Experimental Infection of Sand Flies by Massilia Virus and Viral Transmission by Co-Feeding on Sugar Meal. 38
30970559 2019
2
The Prevalence of Antibodies against Sandfly Fever Viruses and West Nile Virus in Cyprus. 38
31346541 2019
3
NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3. 38
30232186 2018
4
[Sandfly fever-a "neglected" disease]. 38
30151597 2018
5
Emerging arboviruses of clinical importance in Central Asia. 38
30067170 2018
6
Viola phlebovirus is a novel Phlebotomus fever serogroup member identified in Lutzomyia (Lutzomyia) longipalpis from Brazilian Pantanal. 38
29996902 2018
7
Isolation and sequencing of Dashli virus, a novel Sicilian-like virus in sandflies from Iran; genetic and phylogenetic evidence for the creation of one novel species within the Phlebovirus genus in the Phenuiviridae family. 38
29281639 2017
8
Seroprevalence study of Toscana virus and viruses belonging to the Sandfly fever Naples antigenic complex in central and southern Italy. 38
28237695 2017
9
Sandfly fever in Afghanistan-a sometimes overlooked disease of military importance: a case series and review of the literature. 38
29214621 2017
10
Direct evidence for an expanded circulation area of the recently identified Balkan virus (Sandfly fever Naples virus species) in several countries of the Balkan archipelago. 38
28851425 2017
11
Of phlebotomines (sandflies) and viruses: a comprehensive perspective on a complex situation. 38
28805633 2017
12
High Rates of Neutralizing Antibodies to Toscana and Sandfly Fever Sicilian Viruses in Livestock, Kosovo. 38
28518045 2017
13
Characterization of the Bujaru, frijoles and Tapara antigenic complexes into the sandfly fever group and two unclassified phleboviruses from Brazil. 38
28141497 2017
14
Novel and emergent sandfly-borne phleboviruses in Asia Minor: a systematic review. 38
27531681 2017
15
Seroprevalence of sandfly fever virus infection in military personnel on the western border of Iran. 38
27017407 2017
16
Sandfly Fever with Skin Lesions: A Case Series from Turkey. 38
28032114 2016
17
Detection of Leishmania infantum and a Novel Phlebovirus (Balkan Virus) from Sand Flies in Albania. 38
27788062 2016
18
Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR. 38
27248570 2016
19
Neutralization-based seroprevalence of Toscana virus and sandfly fever Sicilian virus in dogs and cats from Portugal. 38
27589865 2016
20
Seroprevalence of Sandfly-Borne Phleboviruses Belonging to Three Serocomplexes (Sandfly fever Naples, Sandfly fever Sicilian and Salehabad) in Dogs from Greece and Cyprus Using Neutralization Test. 38
27783676 2016
21
[Pappataci (sandfly fever) - a little known brought in Poland viral disease]. 38
27755512 2016
22
RNA Encapsidation and Packaging in the Phleboviruses. 38
27428993 2016
23
Phleboviruses associated with sand flies in arid bio-geographical areas of Central Tunisia. 38
26875761 2016
24
Phleboviruses and the Type I Interferon Response. 38
27338447 2016
25
Sadfly fever: two case reports. 38
27489469 2016
26
Complete Coding Sequences of Six Toscana Virus Strains Isolated from Human Patients in France. 38
27231377 2016
27
Sandfly-Borne Phlebovirus Isolations from Turkey: New Insight into the Sandfly fever Sicilian and Sandfly fever Naples Species. 38
27007326 2016
28
Complete Coding Sequences of Three Toscana Virus Strains Isolated from Sandflies in France. 38
26868387 2016
29
Laboratory Validation of the Sand Fly Fever Virus Antigen Assay. 38
26675463 2015
30
In silico analysis and modeling of putative T cell epitopes for vaccine design of Toscana virus. 38
28324549 2015
31
Phlebovirus infections in Greece. 38
25733059 2015
32
[Serological investigation of phlebovirus exposure in blood donors from the Mediterranean Province of Mersin, Turkey]. 38
26313281 2015
33
Toscana virus meningitis case in Switzerland: an example of the ezVIR bioinformatics pipeline utility for the identification of emerging viruses. 38
25658528 2015
34
Phlebovirus infection in Greece: a case report. 38
27418773 2015
35
Reverse genetics system for severe fever with thrombocytopenia syndrome virus. 38
25552716 2015
36
Phlebovirus and Leishmania detection in sandflies from eastern Thrace and northern Cyprus. 38
25499083 2014
37
Seroconversion for infectious pathogens among UK military personnel deployed to Afghanistan, 2008-2011. 38
25418685 2014
38
An outbreak of acute febrile illness caused by Sandfly Fever Sicilian Virus in the Afar region of Ethiopia, 2011. 38
25266349 2014
39
Presence of sandfly-borne phleboviruses of two antigenic complexes (Sandfly fever Naples virus and Sandfly fever Sicilian virus) in two different bio-geographical regions of Tunisia demonstrated by a microneutralisation-based seroprevalence study in dogs. 38
25306250 2014
40
Serosurvey for zoonotic viral and bacterial pathogens among slaughtered livestock in Egypt. 38
25198525 2014
41
New record of the suspected leishmaniasis vector Phlebotomus (Transphlebotomus) mascittii Grassi, 1908 (Diptera: Psychodidae: Phlebotominae)--the northernmost phlebotomine sandfly occurrence in the Palearctic region. 38
24737399 2014
42
Sandfly fever virus as a rare cause of acute viral hepatitis. 38
24602976 2014
43
Viral isolates of a novel putative phlebovirus in the Marche Region of Italy. 38
24534812 2014
44
Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae). 38
24096318 2014
45
Neuroinvasive phlebovirus infection in Greece: a case report. 38
25378100 2014
46
[Acute Toscana virus infection in an anti-HIV positive patient]. 38
24506728 2014
47
Favipiravir (T-705), a novel viral RNA polymerase inhibitor. 38
24084488 2013
48
Sandfly-borne phleboviruses of Eurasia and Africa: epidemiology, genetic diversity, geographic range, control measures. 38
23872312 2013
49
Phlebotomine sandflies and the spreading of leishmaniases and other diseases of public health concern. 38
22924419 2013
50
[Recent advance in phlebovirus]. 38
23905480 2013

Variations for Phlebotomus Fever

Expression for Phlebotomus Fever

Search GEO for disease gene expression data for Phlebotomus Fever.

Pathways for Phlebotomus Fever

Pathways related to Phlebotomus Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.19 IRF9 IRF2

GO Terms for Phlebotomus Fever

Biological processes related to Phlebotomus Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to virus GO:0051607 9.16 IRF9 IRF2
2 interferon-gamma-mediated signaling pathway GO:0060333 8.96 IRF9 IRF2
3 type I interferon signaling pathway GO:0060337 8.62 IRF9 IRF2

Sources for Phlebotomus Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
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44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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