MCID: PHL001
MIFTS: 21

Phlyctenulosis

Categories: Neuronal diseases

Aliases & Classifications for Phlyctenulosis

MalaCards integrated aliases for Phlyctenulosis:

Name: Phlyctenulosis 12 15
Phlyctenular Keratoconjunctivitis 12 71
Strumous Ophthalmia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11581
ICD9CM 34 370.31
SNOMED-CT 67 67895005
ICD10 32 H16.25
UMLS 71 C0155080

Summaries for Phlyctenulosis

MalaCards based summary : Phlyctenulosis, also known as phlyctenular keratoconjunctivitis, is related to rosacea and allergic hypersensitivity disease. An important gene associated with Phlyctenulosis is UBL7 (Ubiquitin Like 7), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Ubiquitin mediated proteolysis. Affiliated tissues include eye, lymph node and testes.

Wikipedia : 74 Phlyctenular keratoconjunctivitis,is an inflammatory syndrome caused by a delayed (aka type-IV)... more...

Related Diseases for Phlyctenulosis

Diseases related to Phlyctenulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 rosacea 10.5
2 allergic hypersensitivity disease 10.3
3 keratoconjunctivitis 10.3
4 blepharitis 10.3
5 mycobacterium tuberculosis 1 10.2
6 exanthem 10.2
7 chlamydia 10.2
8 acute cystitis 10.2
9 cervical adenitis 10.2
10 lymph node tuberculosis 10.2
11 conjunctivitis 10.2
12 lymphadenitis 10.2
13 lice infestation 10.2
14 vasculitis 10.2

Graphical network of the top 20 diseases related to Phlyctenulosis:



Diseases related to Phlyctenulosis

Symptoms & Phenotypes for Phlyctenulosis

Drugs & Therapeutics for Phlyctenulosis

Search Clinical Trials , NIH Clinical Center for Phlyctenulosis

Genetic Tests for Phlyctenulosis

Anatomical Context for Phlyctenulosis

MalaCards organs/tissues related to Phlyctenulosis:

40
Eye, Lymph Node, Testes

Publications for Phlyctenulosis

Articles related to Phlyctenulosis:

(show top 50) (show all 83)
# Title Authors PMID Year
1
Topical Tacrolimus 0.03% for Maintenance Therapy in Steroid-Dependent, Recurrent Phlyctenular Keratoconjunctivitis. 61
29309358 2018
2
Phlyctenulosis: a systemic diagnosis made or missed in the blink of an eye. 61
27704610 2017
3
Phlyctenular keratoconjunctivitis among children in the tertiary eye hospital of Kathmandu, Nepal. 61
26903718 2015
4
ASSOCIATION BETWEEN PHLYCTENULAR CONJUNCTIVITIS AND INTESTINAL PARASITES. 61
26485849 2015
5
Re-emphasizing Thygeson's warning: conjunctival phlyctenulosis as presenting sign of impending clinical tuberculosis. 61
25433746 2014
6
Phlyctenular keratoconjunctivitis associated with Dolosigranulum pigrum. 61
24131340 2014
7
Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy. 61
27625937 2014
8
Successful treatment of phlyctenular keratoconjunctivitis with topical cyclosporin A. 61
23566750 2013
9
Efficacy of azithromycin 1.5% eye drops in childhood ocular rosacea with phlyctenular blepharokeratoconjunctivitis. 61
23514194 2013
10
Tacrolimus ointment 0.03% for treatment of refractory childhood phlyctenular keratoconjunctivitis. 61
22525784 2012
11
The pediatric corneal infiltrate. 61
21597372 2011
12
Scrofuloderma and bilateral anterior staphyloma of eye: an unusual association. 61
21572740 2011
13
Clinical spectrum of pediatric blepharokeratoconjunctivitis. 61
21093331 2010
14
Keratitis in children as seen in a tertiary hospital in Africa. 61
18481476 2008
15
Phlyctenular keratoconjunctivitis in a patient with Staphylococcal blepharitis and ocular rosacea. 61
18302955 2008
16
Resolution of childhood recurrent corneal phlyctenulosis following eradication of an intestinal parasite. 61
18083588 2008
17
[Uveitis during the course of sarcoidosis in a child: difficult diagnosis of a case]. 61
18546926 2008
18
Cutaneous tuberculosis and phlyctenular keratoconjunctivitis: a forgotten association. 61
16880576 2006
19
Tuberculosis and the eye. 61
16986294 2006
20
Topical cyclosporine A in severe steroid-dependent childhood phlyctenular keratoconjunctivitis. 61
16386977 2006
21
Salzmann's nodular degeneration of the cornea: a review and case series. 61
16160490 2005
22
Fascicular keratitis in children: can corneal phlycten be mobile? 61
16181284 2005
23
Recurrent phlyctenular keratoconjunctivitis: a forme fruste manifestation of rosacea. 61
11294589 2001
24
Phlyctenular eye disease: a reappraisal. 61
10715381 2000
25
[Phlyctenular keratoconjunctivitis and lymph node tuberculosis]. 61
10641112 1999
26
[Bouchut's tubercles. Clinical and angiographic study, apropos of a case]. 61
9238476 1997
27
The effect of Staphylococcus aureus phage lysate vaccine on a rabbit model of staphylococcal blepharitis, phlyctenulosis, and catarrhal infiltrates. 61
8694093 1996
28
Phlyctenular keratoconjunctivitis a potentially blinding disorder. 61
22827417 1996
29
Tetracycline treatment of phlyctenulosis. 61
8035976 1994
30
Ocular tuberculosis. 61
8310395 1993
31
Effective treatment of phlyctenular keratoconjunctivitis with oral tetracycline. 61
8371924 1993
32
Antibody studies in a rabbit model of corneal phlyctenulosis and catarrhal infiltrates related to Staphylococcus aureus. 61
2032807 1991
33
SAFA test as an aid to the diagnosis of ocular tuberculosis. 61
2201625 1990
34
Blood histaminase in phlyctenulosis. 61
2517271 1989
35
[Phlyctenular keratoconjunctivitis in bacterial epibulbar infections]. 61
3695265 1987
36
Immunocytological study of phlyctenular eye disease. 61
3493984 1987
37
[Marginal phlyctenular keratoconjunctivitis of tuberculous origin (bovine tuberculosis)]. 61
3568243 1986
38
Survey of ophthalmic conditions in a Labrador community: II. Ocular disease. 61
6478308 1984
39
B- and T-lymphocytes in ocular disease. 61
6235470 1984
40
Phlyctenular keratoconjunctivitis. 61
6863802 1983
41
The phlycten, a come-back? 61
7067601 1982
42
Orally administered tetracycline for phlyctenular keratoconjunctivitis. 61
7270629 1981
43
Rabbit model of phlyctenulosis and catarrhal infiltrates. 61
7236094 1981
44
Phlyctenular keratoconjunctivitis. 61
7264847 1981
45
Phlyctenular eye disease in association with Hymenolepis nana in Egypt. 61
486380 1979
46
Serum immunoglobulins in phlyctenulosis. 61
615148 1977
47
Corneal perforation in nontuberculous (staphylococcal) phlyctenular keratoconjunctivitis. 61
1121999 1975
48
Phlyctenular keratoconjunctivitis: results of penetrating keratoplasty in Alaskan natives. 61
1103040 1975
49
[Treatment of patients with phlyctenular keratoconjunctivitis under dispensary conditions]. 61
4666877 1972
50
Phlyctenulosis. 61
5013255 1972

Variations for Phlyctenulosis

Expression for Phlyctenulosis

Search GEO for disease gene expression data for Phlyctenulosis.

Pathways for Phlyctenulosis

Pathways related to Phlyctenulosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.5 UBC CCNE1
2 11.3 UBC AIRE
3
Show member pathways
11.07 UBC CCNE1
4 10.27 UBC CCNE1

GO Terms for Phlyctenulosis

Sources for Phlyctenulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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