MCID: PHL001
MIFTS: 20

Phlyctenulosis

Categories: Eye diseases

Aliases & Classifications for Phlyctenulosis

MalaCards integrated aliases for Phlyctenulosis:

Name: Phlyctenulosis 12 15
Phlyctenular Keratoconjunctivitis 12 73
Strumous Ophthalmia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11581
ICD10 33 H16.25
ICD9CM 35 370.31
SNOMED-CT 68 193773009 67895005
UMLS 73 C0155080

Summaries for Phlyctenulosis

MalaCards based summary : Phlyctenulosis, also known as phlyctenular keratoconjunctivitis, is related to keratoconjunctivitis and rosacea. An important gene associated with Phlyctenulosis is AOC1 (Amine Oxidase, Copper Containing 1). Affiliated tissues include eye, and related phenotypes are Increased G1 DNA content and Increased HPV18 LCR reporter activity

Wikipedia : 76 Phlyctenular keratoconjunctivitis, also known as phlyctenulosis, is an inflammatory syndrome caused by a... more...

Related Diseases for Phlyctenulosis

Diseases related to Phlyctenulosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 keratoconjunctivitis 10.5
2 rosacea 10.1
3 lymphadenitis 9.9
4 vasculitis 9.9
5 blepharitis 9.9
6 purulent endophthalmitis 9.0 CCNE1 SAMHD1

Graphical network of the top 20 diseases related to Phlyctenulosis:



Diseases related to Phlyctenulosis

Symptoms & Phenotypes for Phlyctenulosis

GenomeRNAi Phenotypes related to Phlyctenulosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased G1 DNA content GR00098-A-1 9.13 AOC1 CCNE1 SAMHD1
2 Increased HPV18 LCR reporter activity GR00197-A-1 8.62 CCNE1 SAMHD1

Drugs & Therapeutics for Phlyctenulosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical, Meibographic and Interferometric Evaluation of Phlyctenular Keratitis in Children - MEIBO-ROSACEE Recruiting NCT03479853

Search NIH Clinical Center for Phlyctenulosis

Genetic Tests for Phlyctenulosis

Anatomical Context for Phlyctenulosis

MalaCards organs/tissues related to Phlyctenulosis:

41
Eye

Publications for Phlyctenulosis

Articles related to Phlyctenulosis:

(show all 25)
# Title Authors Year
1
Topical Tacrolimus 0.03% for Maintenance Therapy in Steroid-Dependent, Recurrent Phlyctenular Keratoconjunctivitis. ( 29309358 )
2018
2
Phlyctenulosis: a systemic diagnosis made or missed in the blink of an eye. ( 27704610 )
2016
3
Phlyctenular keratoconjunctivitis among children in the tertiary eye hospital of Kathmandu, Nepal. ( 26903718 )
2015
4
Re-emphasizing Thygeson's warning: conjunctival phlyctenulosis as presenting sign of impending clinical tuberculosis. ( 25433746 )
2014
5
Phlyctenular Keratoconjunctivitis Associated with Dolosigranulum pigrum. ( 24131340 )
2013
6
Successful treatment of phlyctenular keratoconjunctivitis with topical cyclosporin A. ( 23566750 )
2013
7
Tacrolimus ointment 0.03% for treatment of refractory childhood phlyctenular keratoconjunctivitis. ( 22525784 )
2012
8
Phlyctenular keratoconjunctivitis in a patient with Staphylococcal blepharitis and ocular rosacea. ( 18302955 )
2008
9
Resolution of childhood recurrent corneal phlyctenulosis following eradication of an intestinal parasite. ( 18083588 )
2008
10
Topical cyclosporine A in severe steroid-dependent childhood phlyctenular keratoconjunctivitis. ( 16386977 )
2006
11
Cutaneous tuberculosis and phlyctenular keratoconjunctivitis: a forgotten association. ( 16880576 )
2006
12
The effect of Staphylococcus aureus phage lysate vaccine on a rabbit model of staphylococcal blepharitis, phlyctenulosis, and catarrhal infiltrates. ( 8694093 )
1996
13
Tetracycline treatment of phlyctenulosis. ( 8035976 )
1994
14
Antibody studies in a rabbit model of corneal phlyctenulosis and catarrhal infiltrates related to Staphylococcus aureus. ( 2032807 )
1991
15
Blood histaminase in phlyctenulosis. ( 2517271 )
1989
16
Rabbit model of phlyctenulosis and catarrhal infiltrates. ( 7236094 )
1981
17
Serum immunoglobulins in phlyctenulosis. ( 615148 )
1977
18
Phlyctenulosis. ( 5013255 )
1972
19
Experimental conjunctival phlyctenulosis. ( 5769107 )
1969
20
Histopathological study of phlyctenulosis. ( 5744631 )
1968
21
Phlyctenulosis: its aetiology and relation to endogenous infections. ( 5748417 )
1968
22
Etiology of phlyctenulosis. ( 5830896 )
1965
23
PHLYCTENULOSIS IN THE ESKIMOS OF THE CANADIAN EASTERN ARCTIC. ( 14084699 )
1963
24
Phlyctenulosis. Attempts to produce an experimental model with BCG. ( 13921137 )
1962
25
Tuberculous lymphadenitis, allergic vasculitis and phlyctenulosis; report of a case. ( 13094549 )
1953

Variations for Phlyctenulosis

Expression for Phlyctenulosis

Search GEO for disease gene expression data for Phlyctenulosis.

Pathways for Phlyctenulosis

GO Terms for Phlyctenulosis

Sources for Phlyctenulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....