MCID: PHT004
MIFTS: 33

Photoallergic Dermatitis

Categories: Skin diseases

Aliases & Classifications for Photoallergic Dermatitis

MalaCards integrated aliases for Photoallergic Dermatitis:

Name: Photoallergic Dermatitis 12 15
Dermatitis, Photoallergic 44 73
Photoallergic Contact Dermatitis 12
Photoallergic Eczema 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3818
MeSH 44 D017454
UMLS 73 C0162824

Summaries for Photoallergic Dermatitis

MalaCards based summary : Photoallergic Dermatitis, also known as dermatitis, photoallergic, is related to contact dermatitis and dermatitis. An important gene associated with Photoallergic Dermatitis is AGPS (Alkylglycerone Phosphate Synthase). The drugs Castor oil and Tretinoin have been mentioned in the context of this disorder. Affiliated tissues include testes and skin, and related phenotypes are endocrine/exocrine gland and homeostasis/metabolism

Wikipedia : 76 Photodermatitis, sometimes referred to as sun poisoning or photoallergy, is a form of allergic contact... more...

Related Diseases for Photoallergic Dermatitis

Diseases related to Photoallergic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 contact dermatitis 10.5
2 dermatitis 10.5
3 fungal esophagitis 9.8 ATP12A ATP4A
4 bladder calculus 9.8 ATP12A ATP4A
5 gastrointestinal neuroendocrine benign tumor 9.8 ATP12A ATP4A
6 neonatal candidiasis 9.8 ATP12A ATP4A
7 squamous papillomatosis 9.8 ATP12A ATP4A
8 acute laryngitis 9.8 ATP12A ATP4A
9 gastroduodenal crohn's disease 9.8 ATP12A ATP4A
10 gastric neuroendocrine neoplasm 9.8 ATP12A ATP4A
11 toxic megacolon 9.7 ATP12A ATP4A
12 aspiration pneumonitis 9.7 ATP12A ATP4A
13 postsurgical hypothyroidism 9.7 ATP12A ATP4A
14 gastric antral vascular ectasia 9.7 ATP12A ATP4A
15 esophageal candidiasis 9.7 ATP12A ATP4A
16 duodenitis 9.7 ATP12A ATP4A
17 rumination disorder 9.7 ATP12A ATP4A
18 granulomatous gastritis 9.7 ATP12A ATP4A
19 laryngeal disease 9.7 ATP12A ATP4A
20 ischemic neuropathy 9.7 ATP12A ATP4A
21 capillary disease 9.7 ATP12A ATP4A
22 peptic esophagitis 9.7 ATP12A ATP4A
23 duodenal disease 9.7 ATP12A ATP4A
24 dyskinesia of esophagus 9.7 ATP12A ATP4A
25 hernia, hiatus 9.7 ATP12A ATP4A
26 congenital disorder of deglycosylation 9.7 ATP12A ATP4A
27 anismus 9.7 ATP12A ATP4A
28 esophageal atresia/tracheoesophageal fistula 9.7 ATP12A ATP4A
29 laryngitis 9.7 ATP12A ATP4A
30 laryngeal tuberculosis 9.7 ATP12A ATP4A
31 lymphocytic colitis 9.7 ATP12A ATP4A
32 clostridium difficile colitis 9.7 ATP12A ATP4A
33 lower urinary tract calculus 9.6 ATP12A ATP4A
34 aspiration pneumonia 9.6 ATP12A ATP4A
35 diarrhea 1, secretory chloride, congenital 9.6 ATP12A ATP4A
36 chronic laryngitis 9.6 ATP12A ATP4A
37 chronic intestinal vascular insufficiency 9.6 ATP12A ATP4A
38 eosinophilic gastritis 9.6 ATP12A ATP4A
39 polyposis, skin pigmentation, alopecia, and fingernail changes 9.6 ATP12A ATP4A
40 esophageal varix 9.6 ATP12A ATP4A
41 esophagus adenocarcinoma 9.6 ATP12A ATP4A
42 myopathy, x-linked, with excessive autophagy 9.6 ATP12A ATP4A
43 gastric lymphoma 9.5 ATP12A ATP4A
44 pancreatic steatorrhea 9.5 ATP12A ATP4A
45 pneumatosis cystoides intestinalis 9.5 ATP12A ATP4A
46 superior mesenteric artery syndrome 9.5 ATP12A ATP4A
47 jejunoileitis 9.5 ATP12A ATP4A
48 lateral medullary syndrome 9.4 ATP12A ATP4A
49 paine syndrome 9.4 ATP12A ATP4A
50 esophagitis, eosinophilic, 1 9.4 ATP12A ATP4A

Graphical network of the top 20 diseases related to Photoallergic Dermatitis:



Diseases related to Photoallergic Dermatitis

Symptoms & Phenotypes for Photoallergic Dermatitis

MGI Mouse Phenotypes related to Photoallergic Dermatitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.26 AGPS ATP4A EHD1 PTGS2
2 homeostasis/metabolism MP:0005376 9.02 AGPS ATP12A ATP4A EHD1 PTGS2

Drugs & Therapeutics for Photoallergic Dermatitis

Drugs for Photoallergic Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Castor oil Approved, Investigational, Nutraceutical, Vet_approved Phase 1 8001-79-4
2
Tretinoin Approved, Investigational, Nutraceutical Phase 1 302-79-4 5538 444795
3 Cathartics Phase 1
4 Gastrointestinal Agents Phase 1
5 Laxatives Phase 1
6 Dermatologic Agents Phase 1,Not Applicable
7 Keratolytic Agents Phase 1
8 Castor Nutraceutical Phase 1
9
Benzophenone Approved Not Applicable 119-61-9 3102
10
Camphor Approved Not Applicable 464-49-3 159055
11
Diclofenac Approved, Vet_approved Not Applicable 15307-86-5 3033
12
Ibuprofen Approved Not Applicable 15687-27-1 3672
13
Ketoprofen Approved, Vet_approved Not Applicable 22071-15-4 3825
14
Oxybenzone Approved Not Applicable 131-57-7 4632
15
Piroxicam Approved, Investigational Not Applicable 36322-90-4 5280452 54676228
16 Sunscreening Agents Not Applicable
17 Protective Agents Not Applicable
18 Radiation-Protective Agents Not Applicable
19 Pharmaceutical Solutions Not Applicable
20 Analgesics Not Applicable
21 Analgesics, Non-Narcotic Not Applicable
22 Anti-Inflammatory Agents Not Applicable
23 Anti-Inflammatory Agents, Non-Steroidal Not Applicable
24 Antirheumatic Agents Not Applicable
25 octylmethoxycinnamate Not Applicable
26 Peripheral Nervous System Agents Not Applicable
27 Photosensitizing Agents Not Applicable
28 Salicylates Not Applicable
29 Terephthalylidene dicamphor sulfonic acid Not Applicable

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment Completed NCT00645164 Phase 1 Xenaderm
2 NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers Completed NCT00605956 Phase 1 NatrOVA Creme Rinse - 1%;NatrOVA Creme Rinse Vehicle Only;Blank Patch
3 Clinical Evaluation of the Photoallergy Potential of Atralin Gel Completed NCT00603772 Phase 1 Atralin (tretinoin) gel, 0.05%
4 Human Photoallergy Test (824/2016) Completed NCT02962869 Not Applicable BAY987517
5 To Test for Photo Allergy Reaction of Sunscreens Completed NCT02872220 Not Applicable SPF 50 Y65 110 (BAY987519);SPF 50 Y51 002 (BAY987519);SPF 15 V27 104 (BAY987519);Sodium chloride [NaCl]
6 18349-Human Photoallergy Test Completed NCT02823496 Not Applicable
7 Human Photoallergy Test Completed NCT02751515 Not Applicable
8 18850 - Human Photoallergy Test Completed NCT02751463 Not Applicable Sunscreening Sport Spray Rest (BAY987519)
9 18793 - Human Photoallergy Test Completed NCT02750488 Not Applicable BAY987517
10 Human Photoallergy Test Completed NCT02750449 Not Applicable Sun screening Sport Lotion, (BAY987516)
11 To Assess the Photosensitisation and Photoallergy Potential of a Cosmetic Facial Product in Healthy Participants Completed NCT03183518 Not Applicable
12 Multi-Centre European Photopatch Test Study Completed NCT00530387 Not Applicable 19 organic sunscreen filters and 5 topical NSAIDs
13 18776 - Human Photoallergy Test Withdrawn NCT02751567 Not Applicable

Search NIH Clinical Center for Photoallergic Dermatitis

Cochrane evidence based reviews: dermatitis, photoallergic

Genetic Tests for Photoallergic Dermatitis

Anatomical Context for Photoallergic Dermatitis

MalaCards organs/tissues related to Photoallergic Dermatitis:

41
Testes, Skin

Publications for Photoallergic Dermatitis

Articles related to Photoallergic Dermatitis:

(show all 11)
# Title Authors Year
1
Photoallergic dermatitis associated with fixed-dose combination of antiretroviral agent (abacavir-lamivudine-dolutegravir). ( 29851666 )
2018
2
Ketoprofen-induced photoallergic dermatitis. ( 28474616 )
2016
3
Esomeprazole-induced photoallergic dermatitis. ( 20739778 )
2010
4
Generation of reactive intermediates in photoallergic dermatitis. ( 20585243 )
2010
5
Photoallergic dermatitis induced by diltiazem. ( 17244089 )
2007
6
Phototoxic and photoallergic dermatitis caused by hydroxychloroquine. ( 15186388 )
2004
7
Efavirenz-induced photoallergic dermatitis in HIV. ( 11400003 )
2001
8
Photoallergic dermatitis to a pig feed additive. ( 7646399 )
1995
9
Photoallergic dermatitis from ethylenediamine. ( 3709156 )
1986
10
Photoallergic dermatitis from 8-methoxypsoralen. ( 148873 )
1978
11
Allergic and photoallergic dermatitis from diphenhydramine. ( 952531 )
1976

Variations for Photoallergic Dermatitis

Expression for Photoallergic Dermatitis

Search GEO for disease gene expression data for Photoallergic Dermatitis.

Pathways for Photoallergic Dermatitis

GO Terms for Photoallergic Dermatitis

Biological processes related to Photoallergic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.43 ATP12A ATP4A
2 sodium ion transport GO:0006814 9.4 ATP12A ATP4A
3 potassium ion import GO:0010107 9.37 ATP12A ATP4A
4 ATP hydrolysis coupled proton transport GO:0015991 9.32 ATP12A ATP4A
5 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
6 cellular potassium ion homeostasis GO:0030007 9.16 ATP12A ATP4A
7 sodium ion export across plasma membrane GO:0036376 8.96 ATP12A ATP4A
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP12A ATP4A

Molecular functions related to Photoallergic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Photoallergic Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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