MCID: PLC004
MIFTS: 25

Pilocytic Astrocytoma of Cerebellum

Categories: Cancer diseases, Neuronal diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Pilocytic Astrocytoma of Cerebellum

MalaCards integrated aliases for Pilocytic Astrocytoma of Cerebellum:

Name: Pilocytic Astrocytoma of Cerebellum 11 14 71
Cerebellar Pilocytic Astrocytoma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4853
NCIt 49 C6809
SNOMED-CT 68 277507004
UMLS 71 C0349620

Summaries for Pilocytic Astrocytoma of Cerebellum

MalaCards based summary: Pilocytic Astrocytoma of Cerebellum, also known as cerebellar pilocytic astrocytoma, is related to neurofibromatosis, type i and ganglioglioma, and has symptoms including nausea and vomiting and headache. An important gene associated with Pilocytic Astrocytoma of Cerebellum is KIAA1549 (KIAA1549), and among its related pathways/superpathways are Disease and RAF/MAP kinase cascade. Affiliated tissues include cerebellum, brain and tongue.

Related Diseases for Pilocytic Astrocytoma of Cerebellum

Diseases related to Pilocytic Astrocytoma of Cerebellum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 neurofibromatosis, type i 30.4 NF1 KIAA1549 IDH1
2 ganglioglioma 30.1 NF1 H3-3A BRAF
3 obstructive hydrocephalus 30.0 NF1 KIAA1549 H3-3A
4 juvenile pilocytic astrocytoma 29.8 NF1 KIAA1549 IDH1 H3-3A
5 pleomorphic xanthoastrocytoma 29.3 NF1 KIAA1549 IDH1 H3-3A FAM131B BRAF
6 pilocytic astrocytoma 29.1 TACC1 RNF130 NF1 KIAA1549 IDH1 H3-3A
7 cerebellar astrocytoma 28.1 TACC1 RNF130 PNKP NF1 KIAA1549 IDH1
8 glioma susceptibility 1 10.3
9 simple partial epilepsy 10.2 KIAA1549 IDH1
10 hydrocephalus 10.2
11 mutism 10.2
12 neurofibromatosis 10.2
13 low-grade astrocytoma 10.2
14 chordoid glioma 10.2 KIAA1549 IDH1
15 gangliocytoma 10.2 KIAA1549 IDH1
16 chondroma 10.2 NF1 IDH1
17 epidural spinal canal neoplasm 10.2 NF1 KIAA1549
18 astroblastoma 10.2 KIAA1549 IDH1
19 optic nerve astrocytoma 10.2 NF1 IDH1
20 rela fusion-positive ependymoma 10.2 KIAA1549 IDH1
21 spinal cord oligodendroglioma 10.2 NF1 IDH1
22 glioblastoma 10.2
23 acral lentiginous melanoma 10.1 NF1 BRAF
24 mixed glioma 10.1 NF1 IDH1
25 central neurocytoma 10.1 KIAA1549 IDH1
26 non-langerhans-cell histiocytosis 10.1 NF1 BRAF
27 optic nerve neoplasm 10.1 NF1 KIAA1549 FAM131B
28 pulmonic stenosis 10.1 NF1 BRAF
29 subependymal glioma 10.1 NF1 KIAA1549 IDH1
30 pseudohypoparathyroidism, type ia 10.1
31 thyroid cancer, nonmedullary, 1 10.1
32 autism 10.1
33 neurofibromatosis-noonan syndrome 10.1
34 meningioma, familial 10.1
35 iron overload 10.1
36 autism spectrum disorder 10.1
37 central diabetes insipidus 10.1
38 hemosiderosis 10.1
39 quadriplegia 10.1
40 reading disorder 10.1
41 thrombocytopenia 10.1
42 malignant astrocytoma 10.1
43 turner syndrome 10.1
44 central nervous system cancer 10.1
45 pituitary adenoma 10.1
46 pseudohypoparathyroidism 10.1
47 adenoma 10.1
48 diabetes insipidus 10.1
49 intracranial hypertension 10.1
50 meningitis 10.1

Graphical network of the top 20 diseases related to Pilocytic Astrocytoma of Cerebellum:



Diseases related to Pilocytic Astrocytoma of Cerebellum

Symptoms & Phenotypes for Pilocytic Astrocytoma of Cerebellum

UMLS symptoms related to Pilocytic Astrocytoma of Cerebellum:


nausea and vomiting; headache

Drugs & Therapeutics for Pilocytic Astrocytoma of Cerebellum

Search Clinical Trials, NIH Clinical Center for Pilocytic Astrocytoma of Cerebellum

Genetic Tests for Pilocytic Astrocytoma of Cerebellum

Anatomical Context for Pilocytic Astrocytoma of Cerebellum

Organs/tissues related to Pilocytic Astrocytoma of Cerebellum:

MalaCards : Cerebellum, Brain, Tongue

Publications for Pilocytic Astrocytoma of Cerebellum

Articles related to Pilocytic Astrocytoma of Cerebellum:

(show top 50) (show all 75)
# Title Authors PMID Year
1
Novel Use of the Aurora Surgiscope System for Minimally Invasive Resection of Intraparenchymal Lesions: A Case Series. 62
35972079 2022
2
Infiltration in Pilocytic Astrocytoma: A Diagnostic Pitfall. 62
36120224 2022
3
The Utility of Intraoperative Magnetic Resonance Imaging in the Resection of Cerebellar Hemispheric Pilocytic Astrocytomas: A Cohort Study. 62
35147577 2022
4
Outcome of Childhood Cerebellar Pilocytic Astrocytoma: A Series With 20 Years of Follow Up. 62
35350495 2022
5
Corrigendum to: Cerebellar Pilocytic Astrocytoma with a Sacral Drop Metastasis in an Adult. 62
35098311 2022
6
Occipital Intradiploic Pseudomeningocele - A Rare Complication of Pediatric Posterior Cranial Fossa Surgery: Case Report and Review of the Literature. 62
35988537 2022
7
Large Residual Pilocytic Astrocytoma After Failed Ultrasound-Guided Resection: Intraoperative Ultrasound Limitations Require Special Attention. 62
33819702 2021
8
Rapid Recurrence and Anaplastic Transformation of a Pilocytic Astrocytoma in an Elderly Patient: Case Report and Review of the Literature. 62
32634636 2020
9
Supratentorial extension of large cerebellar pilocytic astrocytoma in adult. 62
29446978 2020
10
Low-Grade Gliomas in Patients with Noonan Syndrome: Case-Based Review of the Literature. 62
32806529 2020
11
Postoperative Tetraplegia to a Child after Cerebellar Pilocytic Astrocytoma Excision at Prone Position: Case Report and Literature Review. 62
32161253 2020
12
Pediatric cerebellar pilocytic astrocytoma presenting with spontaneous intratumoral hemorrhage. 62
29569086 2020
13
Deadly Proliferation and Transformation of Pilocytic Astrocytoma in Pregnancy. 62
31574330 2020
14
In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma. 62
33206716 2020
15
Functional herniated choroid plexus in brain parenchyma following VP shunt removal. 62
31913712 2020
16
Co-existent pilocytic astrocytoma with acute B-cell leukemia within the cerebellum. 62
31408921 2019
17
Childhood cerebellar tumours mirror conserved fetal transcriptional programs. 62
31043743 2019
18
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma. 62
30770993 2019
19
Molecular genetics and therapeutic targets of pediatric low-grade gliomas. 62
30929113 2019
20
Prone versus sitting position in pediatric low-grade posterior fossa tumors. 62
30610475 2019
21
Solid non-enhancing cerebellar pilocytic astrocytoma case report. 62
30366781 2019
22
Mathematical skills in children with pilocytic astrocytoma. 62
30523458 2019
23
An elderly case of malignant small cell glioma with hemorrhage coexistent with a calcified pilocytic astrocytoma component in the cerebellar hemisphere. 62
29851180 2018
24
Cerebellar pilocytic astrocytoma in childhood: Investigating the long-term impact of surgery on cognitive performance and functional outcome. 62
28968151 2018
25
Rare compound heterozygous variants in PNKP identified by whole exome sequencing in a German patient with ataxia-oculomotor apraxia 4 and pilocytic astrocytoma. 62
29498415 2018
26
Longitudinal mutational analysis of a cerebellar pilocytic astrocytoma recurring as a ganglioglioma. 62
27718322 2017
27
Posterior Fossa Tumors. 62
27889018 2017
28
Postoperative surveillance of pediatric cerebellar pilocytic astrocytoma. 62
27502785 2016
29
Massive Calcified Cerebellar Pilocytic Astrocytoma with Rapid Recurrence : A Rare Case. 62
27651876 2016
30
A rare case of infantile cerebellar pilocytic astrocytoma and thrombocytopenia presenting with intratumoral hemorrhage. 62
27857799 2016
31
BRAF V600E-mutated diffuse glioma in an adult patient: a case report and review. 62
26445861 2016
32
Nocardia farcinica Meningitis Masquerading as Central Nervous System Metastasis in a Child With Cerebellar Pilocytic Astrocytoma. 62
26181420 2015
33
Clinical evidence of the role of the cerebellum in the suppression of overt articulatory movements during reading. A study of reading in children and adolescents treated for cerebellar pilocytic astrocytoma. 62
25326652 2015
34
Morphological brain lesions of pediatric cerebellar tumor survivors correlate with inferior neurocognitive function but do not affect health-related quality of life. 62
25686892 2015
35
Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma. 62
25883769 2015
36
Long-term functional outcome of patients with cerebellar pilocytic astrocytoma surgically treated in childhood. 62
25383654 2015
37
Spontaneous Malignant Transformation of a Pilocytic Astrocytoma of Cerebellum: Case Report. 62
28503586 2015
38
IDH1 R132H mutation in a pilocytic astrocytoma: a case report. 62
26617931 2015
39
Transformation of adult cerebellar pilocytic astrocytoma to glioblastoma. 62
23884731 2014
40
Long-term quality of life in children treated for posterior fossa brain tumors. 62
23829377 2013
41
Cerebellar pilocytic astrocytoma in adults: a management paradigm for a rare tumour. 62
23793962 2013
42
Metachronous, multicentric glioma of pilocytic astrocytoma with oligodendroglioma-like component and oligodendroglioma through distinct genetic aberrations. 62
23082883 2013
43
Short lasting activity-related headaches with sudden onset in children: a case-based reasoning on classification and diagnosis. 62
23565626 2013
44
Hemorrhagic onset of cerebellar pilocytic astrocytoma in an adult: a case report and review of the literature implying a possible relation of degenerative vascular changes to the massive intratumoral hemorrhage. 62
22009025 2012
45
Infantile cerebellar pilocytic astrocytoma with autism spectrum disorder. 62
22791126 2012
46
Multicompartmental cerebrospinal fluid dissemination of cerebellar pilocytic astrocytoma at presentation. 62
21764319 2011
47
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. 62
21274720 2011
48
Primary cerebellar pilocytic astrocytoma with anaplastic features in a patient with neurofibromatosis type 1 - case report - . 62
21515958 2011
49
Pediatric cerebellar pilocytic astrocytoma presenting with hemorrhage. 62
21150081 2010
50
Chronic uncal herniation secondary to posterior fossa shunting: case report and literature review. 62
19915852 2010

Variations for Pilocytic Astrocytoma of Cerebellum

Expression for Pilocytic Astrocytoma of Cerebellum

Search GEO for disease gene expression data for Pilocytic Astrocytoma of Cerebellum.

Pathways for Pilocytic Astrocytoma of Cerebellum

Pathways related to Pilocytic Astrocytoma of Cerebellum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 NF1 KIAA1549 IDH1 H3-3A FAM131B CLCN6
2
Show member pathways
12.78 NF1 KIAA1549 FAM131B CLCN6 BRAF
3
Show member pathways
11.2 NF1 KIAA1549 FAM131B CLCN6 BRAF
4
Show member pathways
10.92 NF1 BRAF

GO Terms for Pilocytic Astrocytoma of Cerebellum

Sources for Pilocytic Astrocytoma of Cerebellum

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....