MCID: PNL009
MIFTS: 18

Pineal Region Choriocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Pineal Region Choriocarcinoma

MalaCards integrated aliases for Pineal Region Choriocarcinoma:

Name: Pineal Region Choriocarcinoma 12 15 70
Pineal Choriocarcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5553
NCIt 50 C6759
UMLS 70 C1335414

Summaries for Pineal Region Choriocarcinoma

MalaCards based summary : Pineal Region Choriocarcinoma, also known as pineal choriocarcinoma, is related to precocious puberty and choriocarcinoma. An important gene associated with Pineal Region Choriocarcinoma is CD34 (CD34 Molecule), and among its related pathways/superpathways is Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include pineal and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pineal Region Choriocarcinoma

Graphical network of the top 20 diseases related to Pineal Region Choriocarcinoma:



Diseases related to Pineal Region Choriocarcinoma

Symptoms & Phenotypes for Pineal Region Choriocarcinoma

GenomeRNAi Phenotypes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

26 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.5 IGF1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.5 IGF1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-139 9.5 CD34 IGF1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.5 IGF1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.5 IGF1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.5 IGF1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.5 IGF1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-193 9.5 IGF1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-203 9.5 CD34
10 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.5 IGF1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.5 CD34
12 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.5 IGF1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.5 CD34
14 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.5 IGF1

Drugs & Therapeutics for Pineal Region Choriocarcinoma

Search Clinical Trials , NIH Clinical Center for Pineal Region Choriocarcinoma

Genetic Tests for Pineal Region Choriocarcinoma

Anatomical Context for Pineal Region Choriocarcinoma

MalaCards organs/tissues related to Pineal Region Choriocarcinoma:

40
Pineal, Spinal Cord

Publications for Pineal Region Choriocarcinoma

Articles related to Pineal Region Choriocarcinoma:

# Title Authors PMID Year
1
Tumor cells forming sinusoids connected to vasculature are involved in hemorrhage of pineal choriocarcinoma. 61
24847965 2014
2
[Pineal choriocarcinoma: report of a case]. 61
21215172 2010
3
[Intratumoral hemorrhage in choriocarcinoma during neuroendoscopic third ventriculostomy: case report]. 61
16529025 2006
4
Cervical spinal cord infarction after surgery for a pineal region choriocarcinoma in the sitting position: case report. 61
9149270 1997
5
CT of pineal tumors and intracranial germ-cell tumors. 61
2554702 1989
6
CT of pineal tumors and intracranial germ-cell tumors. 61
2476011 1989
7
[Pineal choriocarcinoma presenting massive ventricular hemorrhage--a case report]. 61
3840234 1985
8
Primary intracranial choriocarcinoma: a report of two cases and a review of the literature. 61
6541765 1984
9
hCG beta producing pineal choriocarcinoma. 61
6184187 1982
10
Primary pineal choriocarcinoma with hemorrhage monitored by computerized tomography. Case report. 61
7196441 1981

Variations for Pineal Region Choriocarcinoma

Expression for Pineal Region Choriocarcinoma

Search GEO for disease gene expression data for Pineal Region Choriocarcinoma.

Pathways for Pineal Region Choriocarcinoma

Pathways related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.6 IGF1 CD34

GO Terms for Pineal Region Choriocarcinoma

Biological processes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.16 IGF1 CD34
2 negative regulation of gene expression GO:0010629 8.96 IGF1 CD34
3 negative regulation of tumor necrosis factor production GO:0032720 8.62 IGF1 CD34

Sources for Pineal Region Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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