MCID: PNL009
MIFTS: 23

Pineal Region Choriocarcinoma

Categories: Cancer diseases
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Aliases & Classifications for Pineal Region Choriocarcinoma

MalaCards integrated aliases for Pineal Region Choriocarcinoma:

Name: Pineal Region Choriocarcinoma 11 14 71
Pineal Choriocarcinoma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:5553
NCIt 49 C6759
UMLS 71 C1335414

Summaries for Pineal Region Choriocarcinoma

MalaCards based summary: Pineal Region Choriocarcinoma, also known as pineal choriocarcinoma, is related to secondary hypertrophic osteoarthropathy and potter's syndrome. An important gene associated with Pineal Region Choriocarcinoma is CD34 (CD34 Molecule), and among its related pathways/superpathways is Hair follicle development: cytodifferentiation - part 3 of 3. Affiliated tissues include pineal and spinal cord, and related phenotypes are Reduced mammosphere formation and renal/urinary system

Related Diseases for Pineal Region Choriocarcinoma

Diseases related to Pineal Region Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 278)
# Related Disease Score Top Affiliating Genes
1 secondary hypertrophic osteoarthropathy 10.2 IGF1 CD34
2 potter's syndrome 10.2 IGF1 CD34
3 spinal cord sarcoma 10.2 DICER1 CD34
4 gastric hemangioma 10.2 CHGA CD34
5 skin tag 10.2 IGF1 CD34
6 glomangiomatosis 10.2 SYP CD34
7 lung meningioma 10.2 SYP CD34
8 glomangiomyoma 10.2 SYP CD34
9 glomangiosarcoma 10.2 SYP CD34
10 liver leiomyosarcoma 10.1 CHGA CD34
11 subungual glomus tumor 10.1 SYP CD34
12 meckel diverticulum 10.1 CHGA CD34
13 sclerosing hepatic carcinoma 10.1 CHGA CD34
14 chordoid meningioma 10.1 SYP CD34
15 chordoid glioma 10.1 SYP CD34
16 prostate stromal sarcoma 10.1 SYP CD34
17 thymus sarcomatoid carcinoma 10.1 SYP CD34
18 central epithelioid sarcoma 10.1 SYP CD34
19 vulvar proximal-type epithelioid sarcoma 10.1 SYP CD34
20 vulvar granular cell tumor 10.1 ENO2 CD34
21 penis sarcoma 10.1 ENO2 CD34
22 clear cell meningioma 10.1 SYP CD34
23 conventional fibrosarcoma 10.1 ENO2 CD34
24 pacinian tumor 10.1 ENO2 CD34
25 pancreas lymphoma 10.1 SYP CHGA
26 angiomyoma 10.1 ENO2 CD34
27 vaginal tubulovillous adenoma 10.1 SYP CHGA
28 mixed ductal-endocrine carcinoma 10.1 SYP CHGA
29 vulvar eccrine porocarcinoma 10.1 SYP CHGA
30 parietal lobe neoplasm 10.1 ENO2 CD34
31 cervical large cell neuroendocrine carcinoma 10.1 SYP CHGA
32 duodenal benign neoplasm 10.1 SYP CHGA
33 acinar cell cystadenocarcinoma 10.1 SYP CHGA
34 spindle cell thymoma 10.1 ENO2 CD34
35 precocious puberty 10.1
36 papillary thymic adenocarcinoma 10.1 SYP CHGA
37 plexiform schwannoma 10.1 ENO2 CD34
38 orbital disease 10.1 SYP CD34
39 breast papillary carcinoma 10.1 SYP CHGA
40 gastric gastrinoma 10.1 SYP CHGA
41 gastrinoma 10.1 SYP CHGA
42 endobronchial leiomyoma 10.1 ENO2 CD34
43 ectopic cushing syndrome 10.1 SYP CHGA
44 binswanger's disease 10.1 SYP CHGA
45 gastrointestinal neuroendocrine benign tumor 10.1 SYP CHGA
46 duodenal gastrinoma 10.1 SYP CHGA
47 dysembryoplastic neuroepithelial tumor 10.1 SYP CD34
48 epithelioid malignant peripheral nerve sheath tumor 10.1 ENO2 CD34
49 malignant triton tumor 10.1 ENO2 CD34
50 extra-adrenal pheochromocytoma 10.1 SYP CHGA

Graphical network of the top 20 diseases related to Pineal Region Choriocarcinoma:



Diseases related to Pineal Region Choriocarcinoma

Symptoms & Phenotypes for Pineal Region Choriocarcinoma

GenomeRNAi Phenotypes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.02 CD34 CHGA DICER1 IGF1 TTR

MGI Mouse Phenotypes related to Pineal Region Choriocarcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 CHGA DICER1 DROSHA IGF1 TTR

Drugs & Therapeutics for Pineal Region Choriocarcinoma

Search Clinical Trials, NIH Clinical Center for Pineal Region Choriocarcinoma

Genetic Tests for Pineal Region Choriocarcinoma

Anatomical Context for Pineal Region Choriocarcinoma

Organs/tissues related to Pineal Region Choriocarcinoma:

MalaCards : Pineal, Spinal Cord

Publications for Pineal Region Choriocarcinoma

Articles related to Pineal Region Choriocarcinoma:

# Title Authors PMID Year
1
Tumor cells forming sinusoids connected to vasculature are involved in hemorrhage of pineal choriocarcinoma. 62
24847965 2014
2
[Pineal choriocarcinoma: report of a case]. 62
21215172 2010
3
[Intratumoral hemorrhage in choriocarcinoma during neuroendoscopic third ventriculostomy: case report]. 62
16529025 2006
4
Cervical spinal cord infarction after surgery for a pineal region choriocarcinoma in the sitting position: case report. 62
9149270 1997
5
CT of pineal tumors and intracranial germ-cell tumors. 62
2554702 1989
6
CT of pineal tumors and intracranial germ-cell tumors. 62
2476011 1989
7
[Pineal choriocarcinoma presenting massive ventricular hemorrhage--a case report]. 62
3840234 1985
8
Primary intracranial choriocarcinoma: a report of two cases and a review of the literature. 62
6541765 1984
9
hCG beta producing pineal choriocarcinoma. 62
6184187 1982
10
Primary pineal choriocarcinoma with hemorrhage monitored by computerized tomography. Case report. 62
7196441 1981

Variations for Pineal Region Choriocarcinoma

Expression for Pineal Region Choriocarcinoma

Search GEO for disease gene expression data for Pineal Region Choriocarcinoma.

Pathways for Pineal Region Choriocarcinoma

Pathways related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.36 IGF1 CD34

GO Terms for Pineal Region Choriocarcinoma

Biological processes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pre-miRNA processing GO:0031054 9.56 DROSHA DICER1
2 RNA phosphodiester bond hydrolysis GO:0090501 9.54 DROSHA DICER1
3 miRNA processing GO:0035196 9.5 DROSHA DICER1
4 miRNA metabolic process GO:0010586 9.46 DROSHA DICER1
5 negative regulation of tumor necrosis factor production GO:0032720 9.43 IGF1 DICER1 CD34
6 negative regulation of neuron death GO:1901215 9.1 ENO2 CHGA CD34

Molecular functions related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ribonuclease III activity GO:0004525 8.92 DROSHA DICER1

Sources for Pineal Region Choriocarcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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