Pineal Region Choriocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Pineal Region Choriocarcinoma

MalaCards integrated aliases for Pineal Region Choriocarcinoma:

Name: Pineal Region Choriocarcinoma ¹² ¹⁵ ⁷³

Pineal Choriocarcinoma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5553

NCIt ⁵⁰ C6759

UMLS ⁷³ C1335414

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Summaries for Pineal Region Choriocarcinoma

MalaCards based summary : Pineal Region Choriocarcinoma, also known as pineal choriocarcinoma, is related to choriocarcinoma and spinal cord infarction. An important gene associated with Pineal Region Choriocarcinoma is IGF1 (Insulin Like Growth Factor 1). Affiliated tissues include pineal and spinal cord, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

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Related Diseases for Pineal Region Choriocarcinoma

Diseases related to Pineal Region Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	choriocarcinoma	10.0
2	spinal cord infarction	10.0
3	malignant pineal area germ cell neoplasm	9.9	CD34 IGF1
4	cell type benign neoplasm	9.8	CD34 IGF1
5	muscular disease	9.8	CD34 IGF1
6	myeloma, multiple	9.8	CD34 IGF1
7	large intestine cancer	9.8	CD34 IGF1
8	ewing sarcoma	9.8	CD34 IGF1
9	dilated cardiomyopathy	9.7	CD34 IGF1

Graphical network of the top 20 diseases related to Pineal Region Choriocarcinoma:

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Symptoms & Phenotypes for Pineal Region Choriocarcinoma

GenomeRNAi Phenotypes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

²⁶ (show all 11)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased shRNA abundance (Z-score < -2)	GR00366-A-104	9.4	IGF1
2	Decreased shRNA abundance (Z-score < -2)	GR00366-A-134	9.4	IGF1
3	Decreased shRNA abundance (Z-score < -2)	GR00366-A-139	9.4	CD34 IGF1
4	Decreased shRNA abundance (Z-score < -2)	GR00366-A-144	9.4	IGF1
5	Decreased shRNA abundance (Z-score < -2)	GR00366-A-153	9.4	IGF1
6	Decreased shRNA abundance (Z-score < -2)	GR00366-A-193	9.4	IGF1
7	Decreased shRNA abundance (Z-score < -2)	GR00366-A-200	9.4	IGF1
8	Decreased shRNA abundance (Z-score < -2)	GR00366-A-203	9.4	CD34
9	Decreased shRNA abundance (Z-score < -2)	GR00366-A-213	9.4	IGF1
10	Decreased shRNA abundance (Z-score < -2)	GR00366-A-34	9.4	IGF1
11	Decreased shRNA abundance (Z-score < -2)	GR00366-A-84	9.4	IGF1

MGI Mouse Phenotypes related to Pineal Region Choriocarcinoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	neoplasm	MP:0002006	8.62	CD34 IGF1

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Drugs & Therapeutics for Pineal Region Choriocarcinoma

Search Clinical Trials , NIH Clinical Center for Pineal Region Choriocarcinoma

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Genetic Tests for Pineal Region Choriocarcinoma

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Anatomical Context for Pineal Region Choriocarcinoma

MalaCards organs/tissues related to Pineal Region Choriocarcinoma:

⁴¹

Pineal, Spinal Cord

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Publications for Pineal Region Choriocarcinoma

Articles related to Pineal Region Choriocarcinoma:

#	Title	Authors	Year
1	Tumor cells forming sinusoids connected to vasculature are involved in hemorrhage of pineal choriocarcinoma. ( 24847965 )	Qi ST...Zhang JL	2014
2	Cervical spinal cord infarction after surgery for a pineal region choriocarcinoma in the sitting position: case report. ( 9149270 )	Nitta H....Igarashi N.	1997
3	hCG beta producing pineal choriocarcinoma. ( 6184187 )	Wass JA...Besser GM	1982
4	Primary pineal choriocarcinoma with hemorrhage monitored by computerized tomography. Case report. ( 7196441 )	Fujii T...Saito K	1981

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Genes for Pineal Region Choriocarcinoma

Genes related to Pineal Region Choriocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	IGF1	Insulin Like Growth Factor 1	Protein Coding	13.94	DISEASES inferred ¹⁵
2	CD34	CD34 Molecule	Protein Coding	4	DISEASES inferred ¹⁵

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Variations for Pineal Region Choriocarcinoma

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Expression for Pineal Region Choriocarcinoma

Search GEO for disease gene expression data for Pineal Region Choriocarcinoma.

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Pathways for Pineal Region Choriocarcinoma

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GO Terms for Pineal Region Choriocarcinoma

Biological processes related to Pineal Region Choriocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of gene expression	GO:0010628	9.16	CD34 IGF1
2	cell proliferation	GO:0008283	8.96	CD34 IGF1
3	negative regulation of gene expression	GO:0010629	8.62	CD34 IGF1

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