MCID: PNL011
MIFTS: 19

Pineal Region Germinoma

Categories: Cancer diseases

Aliases & Classifications for Pineal Region Germinoma

MalaCards integrated aliases for Pineal Region Germinoma:

Name: Pineal Region Germinoma 12 15
Pineal Germinoma 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7428
NCIt 50 C8712
UMLS 70 C0854912

Summaries for Pineal Region Germinoma

MalaCards based summary : Pineal Region Germinoma, also known as pineal germinoma, is related to malignant pineal area germ cell neoplasm and germinoma. An important gene associated with Pineal Region Germinoma is CANT1 (Calcium Activated Nucleotidase 1). Affiliated tissues include pineal, brain and spinal cord.

Related Diseases for Pineal Region Germinoma

Diseases related to Pineal Region Germinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 malignant pineal area germ cell neoplasm 31.9 MLLT6 CANT1
2 germinoma 10.4
3 hydrocephalus 10.3
4 obstructive hydrocephalus 10.1
5 pineoblastoma 10.1
6 brain germinoma 10.1
7 neurilemmoma 10.1
8 central nervous system germinoma 10.1
9 pineal gland cancer 10.1
10 hypopituitarism 10.1
11 diabetes insipidus 10.1
12 pineocytoma 10.1
13 b-cell adult acute lymphocytic leukemia 9.6 ZNF384 MSI2

Graphical network of the top 20 diseases related to Pineal Region Germinoma:



Diseases related to Pineal Region Germinoma

Symptoms & Phenotypes for Pineal Region Germinoma

Drugs & Therapeutics for Pineal Region Germinoma

Search Clinical Trials , NIH Clinical Center for Pineal Region Germinoma

Genetic Tests for Pineal Region Germinoma

Anatomical Context for Pineal Region Germinoma

MalaCards organs/tissues related to Pineal Region Germinoma:

40
Pineal, Brain, Spinal Cord, Testis, Medulla Oblongata

Publications for Pineal Region Germinoma

Articles related to Pineal Region Germinoma:

(show top 50) (show all 161)
# Title Authors PMID Year
1
Multifocal germinoma masquerading as avoidant restrictive food intake disorder: a case of severely decreased food intake and malnutrition. 61
33742154 2021
2
Could Aberrant Migration Explain Metachronous Germ Cell Tumors? 61
33017201 2021
3
[Treatment outcomes in patients with central nervous system germinoma (neuro-ophthalmic aspects)]. 61
33560623 2021
4
[Neuro-ophthalmological symptoms in patients with pineal and suprasellar germinoma]. 61
32779455 2020
5
De Novo Pineal Region Germinoma in the Seventh Decade of Life: A Case Report. 61
31417835 2019
6
Canadian patterns of practice for intracranial germ cell tumors in adolescents and young adults. 61
30937607 2019
7
Autopsy report of a late delayed radiation injury after a period of 45 years. 61
30609132 2019
8
CNS germinoma with extensive calcification: An unusual histologic finding. 61
31025642 2019
9
Emergency irradiation of 3.4Gy/2f in pineal gland germinoma patients with symptomatic hydrocephalus. 61
32922913 2019
10
Fast-developing fatal diffuse leptomeningeal dissemination of a pineal germinoma in a young child: a case report and literature review. 61
30451003 2018
11
A case of bilateral vasculitis associated with pineal germinoma. 61
30094391 2018
12
Paraneoplastic Optic Neuropathy and Pineal Germinoma With Collapsin Response-Mediating Protein Antibodies. 61
29266032 2018
13
Unilateral paraneoplastic optic disc edema and retinal periphlebitis in pineal germinoma. 61
29780941 2018
14
[A Case of Ventriculoperitoneal Shunt Dysfunction in an Adult Secondary to Constipation]. 61
29794314 2018
15
Identification of characteristic features of pineal germinoma that enhance accuracy of preoperative differentiation in pineal region tumors: its significance on optimum surgical treatment. 61
28247123 2018
16
Bifocal germinomas in the pineal region and hypothalamo-neurohypophyseal axis: Primary or metastasis? 61
27475314 2016
17
Parinaud «plus» syndrome in a patient with dysgerminoma. 61
26900044 2016
18
Reversible pure word deafness due to inferior colliculi compression by a pineal germinoma in a young adult. 61
26372938 2015
19
Primary cerebrospinal fluid diagnosis of pineal germinoma. 61
25611570 2015
20
Radiation induced malignant peripheral nerve sheath tumour of the second cervical nerve. 61
24913930 2014
21
Pineal germinoma in a child with interferon-γ receptor 1 deficiency. case report and literature review. 61
25216720 2014
22
Radiation-induced cerebral aneurysm treated with endovascular coil embolization. A case report. 61
25207908 2014
23
Neuroimaging diagnosis of pineal region tumors-quest for pathognomonic finding of germinoma. 61
24777305 2014
24
Unusual behaviour of a pineal germinoma mimicking neurosarcoidosis and metastasising along the endoscopic route. 61
23912659 2013
25
A rare case of a pure testicular seminoma presenting 7 years after a pineal germinoma. 61
24286014 2013
26
Late recurrence of a pineal germinoma 14 years after radiation and chemotherapy: a case report and review of the literature. 61
23774153 2013
27
Pineal germinoma with granulomatous reaction, often a pitfall in endoscopic biopsy. Report of two cases and review of the literature. 61
22280987 2012
28
Disseminated germinoma in the brain and cervical spinal cord 10 years after radiographic resolution of pineal germinoma. 61
22551589 2012
29
Intra-abdominal metastasis of an intracranial germinoma via ventriculo-peritoneal shunt in a 13-year-old female. 61
21501064 2011
30
Late spinal metastases from an isolated pineal region germinoma mimicking a schwannoma. 61
21600775 2011
31
Spontaneous regression of germinoma in the pineal region before endoscopic surgery: a pitfall of modern strategy for pineal germ cell tumors. 61
20949306 2011
32
Development of obsessive-compulsive disorder following a pineal germinoma: a case report. 61
21536703 2011
33
Preoperative Visual Loss is the Main Cause of Irreversible Poor Vision in Children with a Brain Tumor. 61
21994502 2011
34
Mixed testicular germ cell tumour in a patient with previous pineal germinoma. 61
20461442 2011
35
Attention deficit hyperactivity disorder: diagnosis and treatment masking the ophthalmic clinical presentation of a pineal gland tumour in a teenager. 61
20225001 2010
36
Pineal germinoma. 61
21105213 2010
37
Pineal germinoma. 61
20818311 2010
38
Metachronous mediastinal seminoma occurring after intracranial germinoma in an adolescent. 61
19779380 2009
39
Anaplastic astrocytoma post radiotherapy of pineal germinoma. 61
19722057 2009
40
Diagnostic and therapeutic pitfalls in neurosarcoidosis. 61
19681440 2009
41
Primary medulla oblongata germinoma--an unusual posterior fossa tumors in young adults. 61
19282178 2009
42
Pineal germinoma with a prominent epithelioid cell granuloma component: case report. 61
19106497 2008
43
Pineal germinoma morphological features in a liquid-based cerebrospinal fluid sample. 61
18677754 2008
44
Intracranial granulocytic sarcoma after chemotherapy for pineal germinoma and testicular cancer. 61
18802163 2008
45
Metachronous mature teratoma in the corpus callosum occurring 12 years after a pineal germinoma. 61
18590442 2008
46
[Simultaneous suprasellar and pineal germinoma: a case report]. 61
18389460 2008
47
Cavernomas in children with brain tumors: a late complication of radiotherapy. 61
18335155 2008
48
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature. 61
17943970 2008
49
[A case of hypophyseal and pineal germinoma]. 61
18058742 2007
50
Paraneoplastic optic disc oedema and retinal periphlebitis associated with pineal germinoma. 61
17576721 2007

Variations for Pineal Region Germinoma

Expression for Pineal Region Germinoma

Search GEO for disease gene expression data for Pineal Region Germinoma.

Pathways for Pineal Region Germinoma

GO Terms for Pineal Region Germinoma

Biological processes related to Pineal Region Germinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell fate specification GO:0001708 8.62 PRDM14 FKBP8

Molecular functions related to Pineal Region Germinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.02 ZNF384 PRDM14 MLLT6 FKBP8 CANT1

Sources for Pineal Region Germinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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