Pineal Region Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Pineal Region Meningioma

MalaCards integrated aliases for Pineal Region Meningioma:

Name: Pineal Region Meningioma ¹¹ ¹⁴ ⁷¹

Pineal Meningioma ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:8031

NCIt ⁴⁹ C6756

UMLS ⁷¹ C1335418

Sources

Summaries for Pineal Region Meningioma

MalaCards based summary: Pineal Region Meningioma, also known as pineal meningioma, is related to meningioma, familial and nk-cell enteropathy, and has symptoms including headache and seizures. An important gene associated with Pineal Region Meningioma is PTPRS (Protein Tyrosine Phosphatase Receptor Type S), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include pineal, and related phenotype is Increased proliferation.

Sources

Related Diseases for Pineal Region Meningioma

Diseases related to Pineal Region Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 163)

#	Related Disease	Score	Top Affiliating Genes
1	meningioma, familial	10.5
2	nk-cell enteropathy	10.2	SMARCB1 PTPRS
3	pineal parenchymal tumor of intermediate differentiation	10.2	SYP PTPRS
4	intracranial hypotension	10.1	SEPTIN2 CRP
5	full schwannomatosis	10.1	SMARCB1 NF2
6	posterior pituitary gland neoplasm	10.1	SMARCB1 NF2
7	optic nerve astrocytoma	10.1	SYP SMARCB1
8	childhood meningioma	10.1	SMARCB1 NF2
9	peripheral nerve schwannoma	10.1	SMARCB1 NF2
10	cerebral falx meningioma	10.1	SMARCB1 NF2
11	parasagittal meningioma	10.1	SMARCB1 NF2
12	cerebral convexity meningioma	10.1	SMARCB1 NF2
13	optic nerve sheath meningioma	10.1	SMARCB1 NF2
14	plexiform schwannoma	10.1	SMARCB1 NF2
15	schwannomatosis 1	10.1	SMARCB1 NF2
16	olfactory groove meningioma	10.1	SMARCB1 NF2
17	cerebellopontine angle tumor	10.1	SMARCB1 NF2
18	anterior cranial fossa meningioma	10.1	SMARCB1 NF2
19	cellular schwannoma	10.1	SMARCB1 NF2
20	brain meningioma	10.1	SMARCB1 NF2
21	sinonasal undifferentiated carcinoma	10.1	SYP SMARCB1
22	transitional meningioma	10.1	SMARCB1 NF2
23	desmoplastic nodular medulloblastoma	10.1	SYP SMARCB1
24	atypical neurofibroma	10.1	SMARCB1 NF2
25	secretory meningioma	10.1	SMARCB1 NF2
26	optic nerve neoplasm	10.1	SMARCB1 NF2
27	melanotic neurilemmoma	10.1	SMARCB1 NF2
28	schwannoma of twelfth cranial nerve	10.1	SMARCB1 NF2
29	hypoglossal nerve disease	10.1	SMARCB1 NF2
30	ovarian small cell carcinoma	10.1	SYP SMARCB1
31	skull base meningioma	10.1	SMARCB1 NF2
32	spinal canal and spinal cord meningioma	10.1	SMARCB1 NF2
33	spinal meningioma	10.1	SMARCB1 NF2
34	mediastinal lipomatosis	10.1	SYP CRP
35	central epithelioid sarcoma	10.1	SYP SMARCB1
36	meningothelial meningioma	10.1	SMARCB1 NF2
37	vulvar proximal-type epithelioid sarcoma	10.1	SYP SMARCB1
38	spinal cord ependymoma	10.1	SMARCB1 NF2
39	skull base cancer	10.1	SMARCB1 NF2
40	glossopharyngeal nerve disease	10.1	NF2 CRP
41	subungual glomus tumor	10.1	SYP CRP
42	fibrous meningioma	10.1	SMARCB1 NF2
43	keratinizing squamous cell carcinoma	10.1	SYP SMARCB1
44	medulloepithelioma	10.1	SYP SMARCB1
45	paranasal sinus cancer	10.1	SYP SMARCB1
46	malignant olfactory nerve neoplasm	10.1	SYP SMARCB1
47	labyrinthitis	10.1	NF2 CRP
48	embryonal tumor with multilayered rosettes, c19mc-altered	10.1	SYP SMARCB1
49	supratentorial primitive neuroectodermal tumor	10.1	SYP SMARCB1
50	extraosseous chondrosarcoma	10.1	SYP SMARCB1

Graphical network of the top 20 diseases related to Pineal Region Meningioma:

Sources

Symptoms & Phenotypes for Pineal Region Meningioma

UMLS symptoms related to Pineal Region Meningioma:

headache; seizures

GenomeRNAi Phenotypes related to Pineal Region Meningioma according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased proliferation	GR00094-A	8.62	NF2 SMARCB1

Sources

Drugs & Therapeutics for Pineal Region Meningioma

Search Clinical Trials, NIH Clinical Center for Pineal Region Meningioma

Sources

Genetic Tests for Pineal Region Meningioma

Sources

Anatomical Context for Pineal Region Meningioma

Organs/tissues related to Pineal Region Meningioma:

MalaCards : Pineal

Sources

Publications for Pineal Region Meningioma

Articles related to Pineal Region Meningioma:

(show all 18)

#	Title	Authors	PMID	Year
1	Occipital Interhemispheric Transtentorial Approach for a Pineal Region Meningioma with Pseudobulbar Palsy. ⁶²	Alves Junior AC...Zanini MA	35151916	2022
2	[Combined endoscopic and microsurgical resection of pineal region meningiomas by modified Poppen approach]. ⁶²	Wu J...Chen G	35325963	2022
3	Pineal Region Meningioma in a Very Young Child. ⁶²	Gendle C...Salunke P	33596576	2021
4	Rapid regression of a symptomatic pineal region meningioma after presumed spontaneous central infarction. ⁶²	Galloway L...Hayhurst C	27290664	2016
5	68Ga-DOTATATE uptake in pineal gland, a rare physiological variant: case series. ⁶²	Riaz S...Bomanji J	26173444	2015
6	Use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using Poppen's approach: a report of ten cases and a literature review. ⁶²	Li Y...Yu J	21676231	2011
7	[Suboccipital transtentorial approach to pineal region meningiomas by 3D-CTA assistance: surgical considerations]. ⁶²	Yu JL...Li YQ	21609570	2011
8	High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location. ⁶²	Jalali R...Brada M	12069116	2002
9	A case of pineal region meningioma without dural attachment, presented with bilateral hearing impairment. ⁶²	Haque M...Hara M	11862524	2002
10	Peduncular hallucinosis due to a pineal meningioma. Case report. ⁶²	Miyazawa T...Shima K	11565874	2001
11	Pineal region meningioma without dural attachment. ⁶²	Madawi AA...Stevens JM	8799544	1996
12	Surgical removal of pineal region meningioma--three case reports. ⁶²	Matsuda Y...Inagawa T	7566392	1995
13	Hearing impairment resulting from a pineal region meningioma. ⁶²	DeMonte F...al-Mefty O	8474658	1993
14	Pineal meningioma: MRI. ⁶²	Iplikcioglu AC...Buharali Z	8232885	1993
15	Combined supratentorial and infratentorial approach to large pineal-region meningioma. ⁶²	Sekhar LN...Goel A	1536024	1992
16	Meningioma in the pineal region: preoperative diagnosis with CT, MRI, and angiography. ⁶²	Yamazaki T...Ogawa A	1852901	1991
17	[Meningioma of pineal region]. ⁶²	Toyota A...Kanaya H	2215869	1990
18	Pineal region meningioma: report of two cases and literature review. ⁶²	Piatt JH...Campbell GA	6856061	1983

Sources

Genes for Pineal Region Meningioma

Genes related to Pineal Region Meningioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PTPRS	Protein Tyrosine Phosphatase Receptor Type S	Protein Coding	4.93	DISEASES inferred ¹⁴
2	SEPTIN2	Septin 2	Protein Coding	4.64	DISEASES inferred ¹⁴
3	NRL	Neural Retina Leucine Zipper	Protein Coding	4.59	DISEASES inferred ¹⁴
4	SMARCB1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1	Protein Coding	3.79	DISEASES inferred ¹⁴
5	CRP	C-Reactive Protein	Protein Coding	3.76	DISEASES inferred ¹⁴
6	NF2	NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor	Protein Coding	3.68	DISEASES inferred ¹⁴
7	AFP	Alpha Fetoprotein	Protein Coding	3.58	DISEASES inferred ¹⁴
8	CALR	Calreticulin	Protein Coding	3.53	DISEASES inferred ¹⁴
9	SYP	Synaptophysin	Protein Coding	3.22	DISEASES inferred ¹⁴

Sources

Variations for Pineal Region Meningioma

Sources

Expression for Pineal Region Meningioma

Search GEO for disease gene expression data for Pineal Region Meningioma.

Sources

Pathways for Pineal Region Meningioma

Pathways related to Pineal Region Meningioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ³	11.33	SYP NF2 CALR

Sources

GO Terms for Pineal Region Meningioma

Cellular components related to Pineal Region Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	obsolete integral component of synaptic vesicle membrane	GO:0030285	8.62	SYP PTPRS

Biological processes related to Pineal Region Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to organic substance	GO:0071310	8.8	SYP CALR

Molecular functions related to Pineal Region Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	complement component C1q complex binding	GO:0001849	8.92	CRP CALR

Sources

Sources for Pineal Region Meningioma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: PNL003 MIFTS: 22	Pineal Region Meningioma Categories: Cancer diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
Genes Tissues Related diseases Publications Symptoms & Phenotypes Expand all tables