MCID: PNC056
MIFTS: 44

Pineocytoma

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Pineocytoma

MalaCards integrated aliases for Pineocytoma:

Name: Pineocytoma 20 58 54 17 70
Tumor of the Pineal Region 70
Pineal Gland Neoplasm 70
Pinealocytoma 20
Pinealoma 20

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

ICD10 via Orphanet 33 D44.5
UMLS via Orphanet 71 C0917890
Orphanet 58 ORPHA251912
UMLS 70 C0031941 C0917890 C1412004

Summaries for Pineocytoma

GARD : 20 A pineocytoma is a tumor of the pineal gland, a small organ in the brain that makes melatonin (a sleep-regulating hormone ). Pineocytomas most often occur in adults as a solid mass, although they may appear to have fluid-filled (cystic) spaces on images of the brain. Signs and symptoms of pineocytomas include headaches, nausea, hydrocephalus, vision abnormalities, and Parinaud syndrome. Pineocytomas are usually slow-growing and rarely spread to other parts of the body. Treatment includes surgery to remove the pineocytoma; most of these tumors do not regrow ( recur ) after surgery.

MalaCards based summary : Pineocytoma, also known as tumor of the pineal region, is related to pineoblastoma and pineal gland cancer. An important gene associated with Pineocytoma is ASMT (Acetylserotonin O-Methyltransferase), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Lenograstim and Sargramostim have been mentioned in the context of this disorder. Affiliated tissues include pineal, brain and spinal cord, and related phenotypes are nausea and vomiting and hydrocephalus

Wikipedia : 73 Pineocytoma, is a benign, slowly growing tumor of the pineal gland. Unlike the similar condition pineal... more...

Related Diseases for Pineocytoma

Diseases related to Pineocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 318)
# Related Disease Score Top Affiliating Genes
1 pineoblastoma 31.4 SYP SAG GFAP ASMT
2 pineal gland cancer 30.6 SYP SAG GFAP ENO2 ASMT
3 obstructive hydrocephalus 30.0 SYP GFAP ENO2
4 benign ependymoma 29.9 SYP GFAP
5 hydrocephalus 29.8 SYP S100B GFAP ENO2
6 pineal parenchymal tumor of intermediate differentiation 29.8 SYP ENO2 ASMT
7 teratoma 29.7 SYP GFAP ENO2 CHGA
8 retinoblastoma 29.4 SAG LINC01194 ENO2 ASMT
9 cellular ependymoma 29.3 SYP S100B LINC01194 GFAP
10 oligodendroglioma 29.1 SYP S100B GFAP ENO2
11 medulloblastoma 28.4 SYP SAG S100B LINC01194 GFAP ENO2
12 diabetes insipidus 10.3
13 precocious puberty 10.3
14 panophthalmitis 10.3 SYP SAG
15 hypoganglionosis 10.2 SYP S100B
16 delayed sleep phase disorder 10.2 ASMT AANAT
17 extraventricular neurocytoma 10.2 SYP GFAP
18 rosette-forming glioneuronal tumor 10.2 SYP S100B
19 desmoplastic infantile ganglioglioma 10.2 SYP GFAP
20 amegakaryocytic thrombocytopenia, congenital 10.2 ASMT AANAT
21 lung combined type small cell carcinoma 10.2 SYP GFAP
22 chiari malformation 10.2 SYP GFAP
23 tanycytic ependymoma 10.2 SYP GFAP
24 medullomyoblastoma 10.2 SYP GFAP
25 cauda equina syndrome 10.2 SYP GFAP
26 melanoma-associated retinopathy 10.2 SAG RHO
27 cutaneous leiomyosarcoma 10.2 S100B GFAP
28 syringocystadenoma papilliferum 10.2 S100B GFAP
29 hypopituitarism 10.2
30 gliofibroma 10.2 SYP GFAP
31 medulloepithelioma 10.1 SYP GFAP
32 myasthenic syndrome, congenital, 3a, slow-channel 10.1 SAG RHO
33 myxoid chondrosarcoma 10.1 SYP S100B
34 gemistocytic astrocytoma 10.1 S100B GFAP
35 esophageal neuroendocrine tumor 10.1 SYP CHGA
36 acinar cell cystadenocarcinoma 10.1 SYP CHGA
37 vulvar eccrine porocarcinoma 10.1 SYP CHGA
38 pancreatic serous cystadenocarcinoma 10.1 SYP CHGA
39 spindle cell rhabdomyosarcoma 10.1 S100B GFAP
40 gastrointestinal neuroendocrine benign tumor 10.1 SYP CHGA
41 vaginal tubulovillous adenoma 10.1 SYP CHGA
42 mixed ductal-endocrine carcinoma 10.1 SYP CHGA
43 laryngeal small cell carcinoma 10.1 SYP CHGA
44 papillary thymic adenocarcinoma 10.1 SYP CHGA
45 duodenal benign neoplasm 10.1 SYP CHGA
46 syringoma 10.1 S100B GFAP
47 breast papillary carcinoma 10.1 SYP CHGA
48 laryngeal neuroendocrine tumor 10.1 SYP CHGA
49 esophageal adenoid cystic carcinoma 10.1 SYP CHGA
50 gastric neuroendocrine neoplasm 10.1 SYP CHGA

Graphical network of the top 20 diseases related to Pineocytoma:



Diseases related to Pineocytoma

Symptoms & Phenotypes for Pineocytoma

Human phenotypes related to Pineocytoma:

58 31 (show all 14)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 nausea and vomiting 58 31 hallmark (90%) Very frequent (99-80%) HP:0002017
2 hydrocephalus 58 31 hallmark (90%) Very frequent (99-80%) HP:0000238
3 increased intracranial pressure 58 31 hallmark (90%) Very frequent (99-80%) HP:0002516
4 headache 58 31 hallmark (90%) Very frequent (99-80%) HP:0002315
5 memory impairment 58 31 hallmark (90%) Very frequent (99-80%) HP:0002354
6 nystagmus 58 31 frequent (33%) Frequent (79-30%) HP:0000639
7 episodic ataxia 58 31 frequent (33%) Frequent (79-30%) HP:0002131
8 increased csf protein 58 31 frequent (33%) Frequent (79-30%) HP:0002922
9 altitudinal visual field defect 58 31 frequent (33%) Frequent (79-30%) HP:0030531
10 abnormal eyelid morphology 31 frequent (33%) HP:0000492
11 hearing abnormality 58 31 occasional (7.5%) Occasional (29-5%) HP:0000364
12 difficulty walking 58 31 occasional (7.5%) Occasional (29-5%) HP:0002355
13 cognitive impairment 58 Frequent (79-30%)
14 abnormality of the eyelid 58 Frequent (79-30%)

MGI Mouse Phenotypes related to Pineocytoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.23 AANAT CHGA ENO2 GFAP RHO SAG

Drugs & Therapeutics for Pineocytoma

Drugs for Pineocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 108)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lenograstim Approved, Investigational Phase 3 135968-09-1
2
Sargramostim Approved, Investigational Phase 3 123774-72-1, 83869-56-1
3 Immunologic Factors Phase 3
4 Adjuvants, Immunologic Phase 3
5
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
6
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
7
Sirolimus Approved, Investigational Phase 2 53123-88-9 6436030 5284616
8
Ethanol Approved Phase 2 64-17-5 702
9
Sorbitol Approved Phase 2 50-70-4 5780
10
tannic acid Approved Phase 2 1401-55-4
11
Titanium dioxide Approved Phase 2 13463-67-7
12
Dasatinib Approved, Investigational Phase 2 302962-49-8 3062316
13
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
14
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
15
Bevacizumab Approved, Investigational Phase 2 216974-75-3
16
Irinotecan Approved, Investigational Phase 2 100286-90-6, 97682-44-5 60838
17
Vitamin C Approved, Nutraceutical Phase 2 50-81-7 5785 54670067
18
Camptothecin Experimental Phase 2 7689-03-4
19
MK-1775 Investigational Phase 1, Phase 2 955365-80-7, 501-36-0 24856436 445154
20 Anti-Retroviral Agents Phase 1, Phase 2
21 Plerixafor octahydrochloride Phase 1, Phase 2
22 Anti-HIV Agents Phase 1, Phase 2
23 Protein Kinase Inhibitors Phase 2
24 Antibiotics, Antitubercular Phase 2
25 Anti-Bacterial Agents Phase 2
26 Anti-Infective Agents Phase 2
27 Antifungal Agents Phase 2
28 Pharmaceutical Solutions Phase 2
29 Soy Bean Phase 2
30 Carboxymethylcellulose Sodium Phase 2
31 Alkylating Agents Phase 2
32 Angiogenesis Inhibitors Phase 2
33 Antineoplastic Agents, Immunological Phase 2
34 Immunoglobulins, Intravenous Phase 2
35 topoisomerase I inhibitors Phase 2
36 Immunoglobulin G Phase 2
37 Endothelial Growth Factors Phase 2
38
Lenalidomide Approved Phase 1 191732-72-6 216326
39
Bortezomib Approved, Investigational Phase 1 179324-69-7 93860 387447
40
Gemcitabine Approved Phase 1 95058-81-4 60750
41
Trametinib Approved Phase 1 871700-17-3 11707110
42
Vorinostat Approved, Investigational Phase 1 149647-78-9 5311
43
Etoposide Approved Phase 1 33419-42-0 36462
44
Melphalan Approved Phase 1 148-82-3 4053 460612
45
Thiotepa Approved, Investigational Phase 1 52-24-4 5453
46
Cyclophosphamide Approved, Investigational Phase 1 50-18-0, 6055-19-2 2907
47
Carboplatin Approved Phase 1 41575-94-4 10339178 498142 38904
48
Cisplatin Approved Phase 1 15663-27-1 84093 441203 2767
49
Vincristine Approved, Investigational Phase 1 2068-78-2, 57-22-7 5978
50
Isotretinoin Approved Phase 1 4759-48-2 5282379 5538

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Prospective and Randomized Study of Fixed Versus Flexible Prophylactic Administration of Granulocyte Colony-Stimulating Factor (G-CSF) in Children With Cancer Terminated NCT01987596 Phase 3
2 Phase II Prospective Study of Sequential Myeloablative Chemotherapy With Stem Cell Rescue for the Treatment of Selected High Risk CNS Tumors and Recurrent CNS Tumors Completed NCT00179803 Phase 2
3 A Randomized Phase II Trial of Bevacizumab to Control Brain Radiation Damage Completed NCT00492089 Phase 2 bevacizumab;placebo
4 A Phase I/II Study of Local Field Irradiation and Temozolomide Followed by Continuous Infusion Plerixafor as an Upfront Therapy for Newly Diagnosed Glioblastoma GBM Completed NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
5 Proton Radiation for Low Grade Gliomas Completed NCT01024907 Phase 1, Phase 2
6 Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma Recruiting NCT02596828 Phase 2 Temozolomide;Irinotecan;Dasatinib;Rapamycin
7 Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, a COG Randomized Phase II Screening Trial Active, not recruiting NCT01217437 Phase 2 Irinotecan Hydrochloride;Temozolomide
8 A Phase 1/2 Study of AZD1775 (MK-1775) in Combination With Oral Irinotecan in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors Active, not recruiting NCT02095132 Phase 1, Phase 2 Adavosertib;Irinotecan Hydrochloride
9 A Phase 2 Study of Fluorescence Detection of Adult Primary Central Nervous System Tumors in Subjects Receiving Tozuleristide and Imaged With the Canvas System Not yet recruiting NCT04743310 Phase 2 tozuleristide
10 A Phase I Study of SAHA and Temozolomide in Children With Relapsed or Refractory Primary Brain or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
11 A Phase I Clinical Trial of AZD2171 in Children With Recurrent or Progressive Central Nervous System (CNS) Tumors Completed NCT00326664 Phase 1 Cediranib Maleate
12 A Phase I Trial of CC-5013 (Lenalidomide) in Pediatric Patients With Recurrent or Refractory Primary CNS Tumors Completed NCT00100880 Phase 1 lenalidomide
13 Phase I Trial of Temozolomide and O6-Benzylguanine in Pediatric Patients With Recurrent Brain Tumors Completed NCT00052780 Phase 1 O6-benzylguanine;temozolomide
14 Phase I Pilot Study of Stereotaxic Radiosurgery in Patients With Intracranial Neoplasms Completed NCT00019578 Phase 1
15 Phase 1 Trial of RO4929097 in Combination With Standard Radiotherapy and Temozolomide for Newly Diagnosed Malignant Glioma: A Pharmacokinetic and Pharmacodynamic Study Completed NCT01119599 Phase 1 Gamma-Secretase Inhibitor RO4929097;Temozolomide
16 Phase I Study of Cilengitide (EMD 121974) in Children With Refractory Brain Tumors Completed NCT00063973 Phase 1 cilengitide
17 A Phase I Study of ABT-888, an Oral Inhibitor of Poly (ADP-Ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors Completed NCT00946335 Phase 1 veliparib;temozolomide
18 A Phase I Study of Vorinostat and Bortezomib in Children With Refractory or Recurrent Solid Tumors, Including CNS Tumors and Lymphomas Completed NCT00994500 Phase 1 vorinostat;bortezomib
19 Phase 1 Study of EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric Central Nervous System Tumors Recruiting NCT03638167 Phase 1
20 A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms Recruiting NCT04541082 Phase 1 ONC206
21 Phase 1 Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors Recruiting NCT04185038 Phase 1
22 Phase 1 Study of HER2-Specific CAR T Cell Locoregional Immunotherapy for HER2 Positive Recurrent/Refractory Pediatric Central Nervous System Tumors Recruiting NCT03500991 Phase 1
23 Molecularly-Driven Doublet Therapy for All Children With Refractory or Recurrent CNS Malignant Neoplasms and Young Adults With Refractory or Recurrent SHH Medulloblastoma Recruiting NCT03434262 Phase 1 Gemcitabine;ribociclib;sonidegib;trametinib
24 A Phase 1 Study of Entinostat, an Oral Histone Deacetylase Inhibitor, in Pediatric Patients With Recurrent or Refractory Solid Tumors, Including CNS Tumors and Lymphoma Active, not recruiting NCT02780804 Phase 1 Entinostat
25 A Feasibility Study of Vorinostat (SAHA) Combined With Isotretinoin and Chemotherapy in Infants With Embryonal Tumors of the Central Nervous System Active, not recruiting NCT00867178 Phase 1 Carboplatin;Cisplatin;Cyclophosphamide;Etoposide Phosphate;Isotretinoin;Thiotepa;Vincristine Sulfate;Vorinostat
26 Pilot Study of High-Dose Chemotherapy With Busulfan, Melphalan, and Topotecan Followed by Autologous Hematopoietic Stem Cell Transplant in Advanced Stage and Recurrent Tumors Active, not recruiting NCT00638898 Phase 1 busulfan;melphalan;topotecan hydrochloride
27 Microenvironment: Imaging/Implications in Brain Tumors; A Preliminary Investigation of the Biodistribution of [F-18]-EF5 in Patients With Brain Tumors Terminated NCT00110032 Phase 1 EF5
28 Phase I Study of CDK 4-6 Inhibitor PD-0332991 (Palbociclib; IBRANCE) in Children With Recurrent, Progressive or Refractory Central Nervous System Tumors Terminated NCT02255461 Phase 1 palbociclib isethionate
29 A PHASE 1/2 STUDY OF RO4929097, AN ORAL SMALL MOLECULE INHIBITOR OF GAMMA-SECRETASE, IN CHILDREN WITH RELAPSED/REFRACTORY SOLID OR CNS TUMORS, LYMPHOMA, OR T-CELL LEUKEMIA Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
30 A Phase I Study of IMC-A12 (Anti-Insulin-like Growth Factor-I Receptor Monoclonal Antibody) in Combination With CCI-779 (Temsirolimus) in Pediatric Patients With Recurrent or Refractory Solid Tumors Withdrawn NCT01182883 Phase 1 IMC-A12;Temsirolimus
31 A Pilot Study of StrataXRT, a Topical Silicone Barrier, to Prevent Auricular Radiation Dermatitis in Pediatric Patients Undergoing Proton Cerebrospinal Radiation Therapy Withdrawn NCT03990597 Phase 1 Wound Dressing Material
32 Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging Completed NCT01884194
33 Melatonin Replacement Therapy Effects on Cardiac Autonomic Activity in Pinealectomized Patients Completed NCT03885258 Early Phase 1 Melatonin Replacement Therapy
34 International Pleuropulmonary Blastoma Registry for PPB, DICER1 and Associated Conditions Recruiting NCT03382158
35 Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma: An Assessment of Acute Toxicity and Long Term Neurocognitive, Neuroendocrine and Ototoxicity Outcomes Active, not recruiting NCT01063114
36 Phase II Study of Craniospinal and Posterior Fossa Irradiation Using Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma: Assessment of Acute and Long Term Sequelae Active, not recruiting NCT00105560
37 Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome Active, not recruiting NCT00565903
38 Dynamic Contrast Enhanced Steady State T1-Weighted Perfusion MRI (DCE MRI): Characterization of Intracranial Lesions Terminated NCT02967380 Gadobenate Dimeglumine;Gadobutrol
39 Yoga and Brain Cancer: A Feasibility Study Terminated NCT01234805
40 A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes Terminated NCT01251913
41 Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors Withdrawn NCT02194452

Search NIH Clinical Center for Pineocytoma

Genetic Tests for Pineocytoma

Anatomical Context for Pineocytoma

MalaCards organs/tissues related to Pineocytoma:

40
Pineal, Brain, Spinal Cord, Endothelial, Pituitary

Publications for Pineocytoma

Articles related to Pineocytoma:

(show top 50) (show all 326)
# Title Authors PMID Year
1
Simian virus 40 large tumor antigen forms specific complexes with p53 and pRb in human brain tumors. 54 61
11780459 2001
2
Demonstration of hydroxyindole-O-methyltransferase (HIOMT) mRNA expression in pineal parenchymal tumors: histochemical in situ hybridization. 61 54
10831155 2000
3
Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors. 54 61
10570441 1999
4
Tumors of pineal parenchymal cells: a correlation of histological features, including nucleolar organizer regions, with survival in 35 cases. 61 54
7821912 1995
5
Structural and ultrastructural characteristics of human pineal gland, and pineal parenchymal tumors. 61 54
7839826 1994
6
Immunohistochemical characterization of pineocytomas. 61 54
1473313 1992
7
PTEN R130Q Papillary Tumor of the Pineal Region (PTPR) with Chromosome 10 Loss Successfully Treated with Everolimus: A Case Report. 61
33804593 2021
8
Papillary tumor of the pineal region in pediatric populations: An additional case and systematic review of a rare tumor entity. 61
33360024 2021
9
Transcallosal-lateral ventricle-choroid fissure approach for excising large pineal region tumors extending into the third ventricle: experience in 15 pediatric cases. 61
32588176 2021
10
Commentary: Virtual Reality Surgical Rehearsal and 2-Dimensional Operative Video of a Paramedian Supracerebellar Infratentorial Approach Endoscopic Resection of Pineocytoma: 2-Dimensional Operative Video. 61
33377164 2021
11
Commentary: Virtual Reality Surgical Rehearsal and 2-Dimensional Operative Video of a Paramedian Supracerebellar Infratentorial Approach Endoscopic Resection of Pineocytoma: 2-Dimensional Operative Video. 61
33313864 2021
12
Virtual Reality Surgical Rehearsal and 2-Dimensional Operative Video of a Paramedian Supracerebellar Infratentorial Approach Endoscopic Resection of Pineocytoma: 2-Dimensional Operative Video. 61
32895715 2020
13
Devascularization of a Hemorrhagic Pineocytoma by Laser Thermal Ablation Followed by Endoscopic Resection: A Proof-of-Principle Case Report. 61
32360672 2020
14
Papillary tumor of the pineal region: a single-center experience. 61
33133629 2020
15
Radiotherapy for papillary tumor of the pineal region: A systematic review of the literature. 61
31896492 2020
16
Molecular characterization of histopathological ependymoma variants. 61
31679042 2020
17
Second Window Indocyanine Green (SWIG) Near Infrared Fluorescent Transventricular Biopsy of Pineal Tumor. 61
31669685 2020
18
Increased VEGF levels in a case of papillary tumor of the pineal region with intracranial hemorrhage: a potential surrogate indicator of tumor angiogenesis and aggressiveness? 61
26745494 2020
19
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations. 61
31768671 2020
20
Papillary Tumor of the Pineal Region with Parinaud Syndrome: A Case Report. 61
33081665 2020
21
A biphasic tumor in posterior cranial fossa and the pineal region in young adult. 61
32363059 2020
22
Papillary Tumor of the Pineal Region: Systematic Review and Analysis of Prognostic Factors. 61
30989225 2019
23
Pineal apoplexy due to pleomorphic variant pineocytoma. 61
31232273 2019
24
Solitary fibrous tumor of the pineal region with delayed ectopic intracranial metastasis: A case report and review of the literature. 61
31124953 2019
25
Primary pineal tumors - Unraveling histological challenges and certain clinical myths. 61
31085866 2019
26
Papillary Ependymoma of the Spinal Cord: A Case Report with Summary of Prior Published Cases. 61
30937039 2019
27
Usefulness and safety from stereotactic biopsy in posterior fossa lesions in adult patients. 61
31448801 2019
28
Papillary tumor of the pineal region: Case report and review of the literature. 61
29691144 2019
29
Durable response to mTOR inhibition in a patient with relapsing papillary tumor of the pineal region. 61
30295836 2019
30
Recurrent Pineocytomalike Papillary Tumor of The Pineal Region: A Case Report and Literature Review. 61
30165231 2018
31
Microsurgical Resection of Posterior Third Ventricular/Pineal Region Papillary Tumor Via Supracerebellar Infratentorial Approach: 3-Dimensional Operative Video. 61
29788336 2018
32
Papillary Tumor of the Pineal Region in Children: Presentation of a Case and Comprehensive Literature Review. 61
29906576 2018
33
Therapeutic strategy for pineal parenchymal tumor of intermediate differentiation (PPTID): case report of PPTID with malignant transformation to pineocytoma with leptomeningeal dissemination 6 years after surgery. 61
30028263 2018
34
Primary Intracranial Manifestation of a Carcinosarcoma. 61
30283584 2018
35
Masson's tumor of the pineal region: case report. 61
28777021 2018
36
Papillary tumor of the pineal region accompanied by Parinaud's syndrome: magnetic resonance imaging findings. 61
29991845 2018
37
Unedited microneurosurgery of a mixed germ cell tumor of the pineal region. 61
30687573 2018
38
Unedited microneurosurgery of a large recurrent papillary tumor of the pineal region. 61
30595955 2018
39
One burr-hole craniotomy: Posterior interhemispheric approach in Helsinki Neurosurgery. 61
30283716 2018
40
A Case of Nongerminomatous Germ Cell Tumor of the Pineal Region: Risks and Advantages of Biopsy by Endoscopic Approach. 61
29713348 2018
41
Unedited microneurosurgery of a solitary fibrous tumor of the pineal region. 61
30595953 2018
42
Neuropsychological Consequences for Survivors of Childhood Brain Tumor in Malaysia. 61
29896137 2018
43
Histology-Stratified Tumor Control and Patient Survival After Stereotactic Radiosurgery for Pineal Region Tumors: A Report From the International Gamma Knife Research Foundation. 61
28751141 2017
44
Nuclear CRX and FOXJ1 Expression Differentiates Non-Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region. 61
28719464 2017
45
Mixed pineal mature teratoma and germinoma in two brothers of the fraternal triplets. 61
28236067 2017
46
Supraorbital subfrontal trans-laminar endoscope-assisted approach for tumors of the posterior third ventricle. 61
28236180 2017
47
The Role of Adjuvant Radiotherapy in the Treatment of Papillary Tumors of the Pineal Region: Some General Considerations and a Case Report. 61
29271218 2017
48
Atypical Teratoid/Rhabdoid Tumor of the Pineal Region in a Young Adult Male Patient: Case Report and Review of the Literature. 61
27144539 2017
49
Cytologic features of papillary tumor of the pineal region: A case report showing tigroid background. 61
27535020 2016
50
Long-term follow-up of a papillary tumor of the pineal region: addendum to a case report. 61
27568037 2016

Variations for Pineocytoma

Expression for Pineocytoma

Search GEO for disease gene expression data for Pineocytoma.

Pathways for Pineocytoma

Pathways related to Pineocytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.7 TUBB3 SYP SAG S100B RHO GFAP
2 11.03 SYP S100B GFAP
3
Show member pathways
10.5 ASMT AANAT

GO Terms for Pineocytoma

Cellular components related to Pineocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 photoreceptor inner segment GO:0001917 8.8 SAG RHO ENO2

Biological processes related to Pineocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of rhodopsin mediated signaling pathway GO:0022400 9.32 SAG RHO
2 response to light stimulus GO:0009416 9.26 RHO AANAT
3 rhodopsin mediated signaling pathway GO:0016056 9.16 SAG RHO
4 indolalkylamine biosynthetic process GO:0046219 8.96 ASMT AANAT
5 melatonin biosynthetic process GO:0030187 8.62 ASMT AANAT

Sources for Pineocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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