AZUL
MCID: PNT003
MIFTS: 31

Pinta Disease (AZUL)

Categories: Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Pinta Disease

MalaCards integrated aliases for Pinta Disease:

Name: Pinta Disease 12
Pinta 74 52 43 17 71
Endemic Treponematosis Caused by Treponema Carateum 52
Mal Del Pinto 52
Empeines 52
Carate 52
Azul 52
Lota 52
Tina 52

Classifications:



External Ids:

Disease Ontology 12 DOID:1022
MeSH 43 D010874
NCIt 49 C85011
UMLS 71 C0031946 C0153241 C0153242 more

Summaries for Pinta Disease

Disease Ontology : 12 A primary bacterial infectious disease that results in infection located in skin, has material basis in Treponema carateum, which is transmitted by contact with skin and mucous membrane of an infected person. The infection has symptom pruritic plaque, which slowly enlarges and becomes pigmented and hyperkeratotic.

MalaCards based summary : Pinta Disease, also known as pinta, is related to bejel and yaws, and has symptoms including pruritic plaque The drugs Polymethyl Methacrylate and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and testes.

Wikipedia : 74 Pinta (also known as azul, carate, empeines, lota, mal del pinto, and tina) is a human skin disease... more...

Related Diseases for Pinta Disease

Diseases related to Pinta Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 bejel 11.8
2 yaws 10.7
3 syphilis 10.7
4 papillomatosis, confluent and reticulated 10.4
5 myxozoa 10.4
6 secondary syphilis 10.4
7 angelman syndrome 10.3
8 dental caries 10.3
9 late yaws 10.3
10 alcohol use disorder 10.2
11 virus-associated trichodysplasia spinulosa 10.2
12 methane production 10.1
13 helix syndrome 10.1
14 autism spectrum disorder 10.1
15 chagas disease 10.1
16 squamous cell papilloma 10.1
17 papilloma 10.1
18 trichinosis 10.1
19 triiodothyronine receptor auxiliary protein 10.1
20 cardiac arrest 10.1
21 keratosis 10.1
22 skin disease 10.1
23 fatty liver disease 10.1
24 congenital syphilis 10.1
25 treponema infection 10.1

Comorbidity relations with Pinta Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Pinta Disease:



Diseases related to Pinta Disease

Symptoms & Phenotypes for Pinta Disease

Symptoms:

12
  • pruritic plaque

Drugs & Therapeutics for Pinta Disease

Drugs for Pinta Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Polymethyl Methacrylate Phase 4
2 Protective Agents Phase 4
3 Vasodilator Agents Phase 4
4 Dermatologic Agents Phase 3
5
Bezafibrate Approved, Investigational Phase 2 41859-67-0 39042
6 Hypolipidemic Agents Phase 2
7 Antimetabolites Phase 2
8 Lipid Regulating Agents Phase 2
9
Glucagon Approved Early Phase 1 16941-32-5
10
Methamphetamine Approved, Illicit 537-46-2 10836
11
Dopamine Approved 51-61-6, 62-31-7 681
12
Metformin Approved 657-24-9 4091 14219
13 Gastrointestinal Agents Early Phase 1
14 Glucagon-Like Peptide 1 Early Phase 1
15 Incretins Early Phase 1
16 Hormone Antagonists Early Phase 1
17 Hormones Early Phase 1
18 pyruvate Early Phase 1
19 Complement System Proteins
20 Central Nervous System Stimulants
21 Sympathomimetics
22 Dopamine Agents
23 Neurotransmitter Agents
24 Autonomic Agents
25 Dopamine Uptake Inhibitors
26 Adrenergic Agents
27 Liver Extracts
28 Hypoglycemic Agents
29 Pharmaceutical Solutions

Interventional clinical trials:

(show all 20)
# Name Status NCT ID Phase Drugs
1 REmoval of Free Light Chains in Hemodialysis Patients Without Multiple Myeloma. A Crossover COmpaRison of Three Different dialyzERs Completed NCT02950389 Phase 4
2 Study for Dermatological Evaluation of Topic Compatibility (Primary and Accumulated Dermical Irritability, Dermical Sensitivity) of Dermacyd Tina Gel Tangerina Mix. Completed NCT00669058 Phase 3 Lactic acid (Dermacid)
3 Dermatological Evaluation of the Photo Irritation and Photo Sensitivity Potential for Dermacyd Tina Gel Tangerina Mix. Completed NCT00668889 Phase 3 Lactic acid (Dermacid)
4 Study for Dermatological Evaluation of Topic Compatibility (Primary and Accumulated Dermical Irritability, Dermical Sensitivity) of Dermacyd Tina Gel Sweet Flower. Completed NCT00668668 Phase 3 Lactic acid (Dermacid)
5 Dermatological Evaluation of the Photo Irritation and Photo Sensitivity Potential for Dermacyd Tina Gel Sweet Flower. Completed NCT00668629 Phase 3 Lactic acid (Dermacid)
6 Monocentric Study, Phase III, for Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Tina Gel Tangerina Mix Completed NCT00663325 Phase 3 Lactic acid (Dermacid)
7 Monocentric Study, Phase III, for Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Tina Gel Sweet Flower Completed NCT00663273 Phase 3 Lactic acid (Dermacid)
8 A Randomized, Double-blind, Pilot Study of PINTA 745, an Anti-myostatin Peptibody, in Patients With End Stage Renal Disease Who Require Maintenance Hemodialysis and Have Protein Energy Wasting Completed NCT01958970 Phase 1, Phase 2 PINTA 745;Placebo
9 Evaluation of the Effect of Bezafibrate on Muscle Metabolism During Exercise in Patients With CPTII and VLCAD Deficiency Completed NCT00983788 Phase 2 Bezafibrate
10 Study of Ocular Blood Flow Using Laser Doppler Flowmetry in Patients With Glaucoma and/or OSAS Unknown status NCT00874913
11 The Effect of Glucagon on Rates of Hepatic Mitochondrial Oxidation and Pyruvate Carboxylase Flux in Man Assessed by Positional Isotopomer NMR Tracer Analysis (PINTA) Completed NCT03965130 Early Phase 1 Glucagon
12 A Stepped Wedge, Cluster-randomized Impact Evaluation of a Household UV-treatment and Safe Storage Drinking Water Intervention in Rural Baja California Sur, Mexico Completed NCT01637389
13 Contribution of Average Volume Assured Pressure Support (AVAPS) to Efficacy of bi-Level Pressure Support Nocturnal Ventilation and Impact on Sleep Structure Completed NCT00479284
14 Cross-over Study of Three Modular Devices for Aid in Patient Standing and Transfer Completed NCT01647802
15 Protein Supplementation in Dialysis Patients Completed NCT01855295
16 "Non-invasive Measurement of Hepatic Substrate Flux Rates in Patients With Diabetes Mellitus Type 2" Recruiting NCT04088851 Metformin
17 Safety and Efficacy of Low Temperature Contrast for the Treatment of PCI-related Myocardial Injury in Patients With Unstable Angina Pectoris (LOTA-I) Recruiting NCT03700567
18 Safety and Efficacy of Low Temperature Rota-flush Solution for the Treatment of RA-related Myocardial Injury in Patients With Severe Calcified Lesion Undergoing Rotational Atherectomy (RA) (LOTA-II) Recruiting NCT03701230
19 Impact of Plasma Soluble Prorenin Receptor in Obese and Type 2 Diabetic Patients Recruiting NCT03643783
20 Study of Association of Salivary Adipokines With Prediabetes and Type 2 Diabetes Mellitus Active, not recruiting NCT03901248

Search NIH Clinical Center for Pinta Disease

Cochrane evidence based reviews: pinta

Genetic Tests for Pinta Disease

Anatomical Context for Pinta Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Pinta Disease:

19
Skin

MalaCards organs/tissues related to Pinta Disease:

40
Skin, Liver, Testes, Heart

Publications for Pinta Disease

Articles related to Pinta Disease:

(show top 50) (show all 159)
# Title Authors PMID Year
1
Regulation of hepatic mitochondrial oxidation by glucose-alanine cycling during starvation in humans. 61
31545298 2019
2
Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates. 61
31578240 2019
3
The "Scourge of the Renaissance". A short review about Treponema pallidum infection. 61
31625831 2019
4
The potential role of lava lizards as pollinators across the Galápagos islands. 61
30811785 2019
5
Genetics of human and animal uncultivable treponemal pathogens. 61
29578082 2018
6
Point-of-care tests for syphilis and yaws in a low-income setting - A qualitative study of healthcare worker and patient experiences. 61
29672524 2018
7
Chemokine expression in the early response to injury in human airway epithelial cells. 61
29534074 2018
8
A new species of Acanthobothrium (Eucestoda: Onchobothriidae) in Aetobatus cf. narinari (Myliobatidae) from Campeche, México. 61
29538487 2018
9
Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA). 61
29386503 2018
10
Copy Number Variation and Expression Analysis Reveals a Nonorthologous Pinta Gene Family Member Involved in Butterfly Vision. 61
29136137 2017
11
Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA). 61
28986525 2017
12
Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum. 61
28168761 2017
13
Complete mitochondrial genome of the speckled dace Rhinichthys osculus, a widely distributed cyprinid minnow of western North America. 61
26488409 2016
14
Tools for opening new chapters in the book of Treponema pallidum evolutionary history. 61
27498082 2016
15
Pinta: Latin America's Forgotten Disease? 61
26304920 2015
16
Molecular evolution and expression of the CRAL_TRIO protein family in insects. 61
25684408 2015
17
Disease gene prioritization using network and feature. 61
25844670 2015
18
Response to Pinta. 61
25640937 2015
19
A Retrospective Study on Genetic Heterogeneity within Treponema Strains: Subpopulations Are Genetically Distinct in a Limited Number of Positions. 61
26436423 2015
20
How Far into Europe Did Pikas (Lagomorpha: Ochotonidae) Go during the Pleistocene? New Evidence from Central Iberia. 61
26535576 2015
21
Psychosocial Interventions for Problem Alcohol Use in Primary Care Settings (PINTA): Baseline Feasibility Data. 61
25985200 2015
22
Endemic treponemal diseases. 61
25157125 2014
23
Response to Pinta. 61
24980178 2014
24
The endemic treponematoses. 61
24396138 2014
25
Equivalency of Galápagos giant tortoises used as ecological replacement species to restore ecosystem functions. 61
23530938 2013
26
Psychosocial interventions for alcohol use among problem drug users: protocol for a feasibility study in primary care. 61
23912883 2013
27
Advances in the diagnosis of endemic treponematoses: yaws, bejel, and pinta. 61
24205410 2013
28
Serologic cross-reactivity of syphilis, yaws, and pinta. 61
23317070 2013
29
PDA (prolonged depolarizing afterpotential)-defective mutants: the story of nina's and ina's--pinta and santa maria, too. 61
22283778 2012
30
Genetic diversity in Treponema pallidum: implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws. 61
22198325 2012
31
PINTA: a web server for network-based gene prioritization from expression data. 61
21602267 2011
32
Erratum: [Bis(2-pyrid-yl)amine-N,N'](nitrato-O,O')cobalt(II) nitrate. Corrigendum. 61
21522228 2011
33
Sterilisation of hybrid Galapagos tortoises (Geochelone nigra) for island restoration. Part 1: endoscopic oophorectomy of females under ketamine-medetomidine anaesthesia. 61
21257559 2011
34
Sterilisation of hybrid Galapagos tortoises (Geochelone nigra) for island restoration. Part 2: phallectomy of males under intrathecal anaesthesia with lidocaine. 61
21257586 2011
35
NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors. 61
19889630 2010
36
The Nina, the Pinta, and heart rate variability: the search for prognostic indicators after cardiac arrest. 61
19325360 2009
37
Cryptic differentiation in the endemic micromoth Galagete darwini (Lepidoptera, Autostichidae) on Galápagos volcanoes. 61
18765358 2008
38
What's a dentist to do? The Nina, the Pinta, and the Santa Maria. 61
18792730 2008
39
On the origin of the treponematoses: a phylogenetic approach. 61
18235852 2008
40
Endemic treponematosis: review and update. 61
16714199 2006
41
Tropical dermatology: bacterial tropical diseases. 61
16546577 2006
42
[Overview of endemic treponematoses]. 61
16615610 2006
43
Pinta: specific disease or anomalous skin reaction? 61
16107996 2005
44
The clinical appearance of pinta mimics secondary syphilis: another trap of treponematosis? 61
15844083 2005
45
Rhodopsin formation in Drosophila is dependent on the PINTA retinoid-binding protein. 61
15917458 2005
46
New terpenoid constituents from Eunicea pinta. 61
12350138 2002
47
Lack of premating isolation at the base of a phylogenetic tree. 61
18707495 2002
48
The endemic treponematoses. 61
11825779 2002
49
Origin and evolutionary relationships of giant Galápagos tortoises. 61
10557302 1999
50
Pinta in Austria (or Cuba?): import of an extinct disease? 61
10376696 1999

Variations for Pinta Disease

Expression for Pinta Disease

Search GEO for disease gene expression data for Pinta Disease.

Pathways for Pinta Disease

GO Terms for Pinta Disease

Sources for Pinta Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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