MCID: PTT010
MIFTS: 28

Pituitary Infarct

Categories: Endocrine diseases

Aliases & Classifications for Pituitary Infarct

MalaCards integrated aliases for Pituitary Infarct:

Name: Pituitary Infarct 12 15
Pituitary Infarction 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1130
NCIt 51 C27117
SNOMED-CT 69 95830009
UMLS 74 C0342405

Summaries for Pituitary Infarct

MalaCards based summary : Pituitary Infarct, also known as pituitary infarction, is related to diabetes insipidus and empty sella syndrome. An important gene associated with Pituitary Infarct is POMC (Proopiomelanocortin), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, thyroid and pancreas, and related phenotypes are endocrine/exocrine gland and homeostasis/metabolism

Related Diseases for Pituitary Infarct

Diseases related to Pituitary Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
# Related Disease Score Top Affiliating Genes
1 diabetes insipidus 29.7 POMC PRL
2 empty sella syndrome 29.3 IGF1 POMC PRL
3 pituitary hormone deficiency, combined, 2 29.2 IGF1 POMC PRL
4 acromegaly 28.5 AIP IGF1 POMC PRL SST
5 adenohypophysitis 10.1 POMC PRL
6 hypothalamic disease 10.1 POMC PRL
7 sella turcica neoplasm 10.1 POMC PRL
8 tuberculum sellae meningioma 10.1 POMC PRL
9 acth-secreting pituitary adenoma 10.1 POMC PRL
10 abducens nerve disease 10.1 POMC PRL
11 diabetes insipidus, neurohypophyseal 10.1 POMC PRL
12 premenstrual tension 10.1 POMC PRL
13 chromophobe adenoma 10.1 POMC PRL
14 gigantism 10.1 AIP PRL
15 adrenal rest tumor 10.1 POMC PRL
16 gynecomastia 10.1 POMC PRL
17 fasting hypoglycemia 10.1 IGF1 POMC
18 multiple endocrine neoplasia, type iv 10.1 AIP PRL
19 galactorrhea 10.0 IGF1 PRL
20 amenorrhea 10.0 POMC PRL
21 pseudohypoparathyroidism, type ia 10.0 IGF1 PRL
22 mammographic density 10.0 IGF1 PRL
23 opiate dependence 10.0 IGF1 POMC
24 fibromyalgia 10.0 IGF1 PRL
25 chronic fatigue syndrome 10.0 IGF1 POMC
26 bronchus adenoma 10.0 POMC SST
27 bronchial adenomas/carcinoids childhood 10.0 POMC SST
28 overnutrition 10.0 IGF1 POMC
29 anovulation 10.0 IGF1 PRL
30 acanthosis nigricans 10.0 IGF1 PRL
31 pancreatic endocrine carcinoma 10.0 POMC SST
32 craniopharyngioma 10.0 IGF1 PRL
33 ectopic cushing syndrome 9.9 POMC SST
34 prolactin producing pituitary tumor 9.9 PRL SST
35 adrenal gland disease 9.9 POMC SST
36 spinocerebellar degeneration 9.9 PRL SST
37 reproductive system disease 9.9 IGF1 PRL
38 multiple endocrine neoplasia, type i 9.9 PRL SST
39 pituitary apoplexy 9.9 AIP POMC PRL
40 polycystic ovary syndrome 9.9 IGF1 PRL
41 carcinoid syndrome 9.8 IGF1 SST
42 endocrine pancreas disease 9.8 IGF1 SST
43 isolated growth hormone deficiency, type ii 9.8 IGF1 SST
44 thyroid carcinoma, familial medullary 9.8 POMC SST
45 hyperthyroidism 9.8 PRL SST
46 sheehan syndrome 9.8 IGF1 POMC PRL
47 hypothyroidism 9.8 IGF1 POMC PRL
48 hypothyroidism, congenital, nongoitrous, 4 9.8 IGF1 POMC PRL
49 short bowel syndrome 9.8 IGF1 SST
50 hyperandrogenism 9.8 IGF1 POMC PRL

Graphical network of the top 20 diseases related to Pituitary Infarct:



Diseases related to Pituitary Infarct

Symptoms & Phenotypes for Pituitary Infarct

MGI Mouse Phenotypes related to Pituitary Infarct:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.56 AIP IGF1 POMC PRL
2 homeostasis/metabolism MP:0005376 9.55 AIP IGF1 POMC PRL SST
3 integument MP:0010771 9.26 AIP IGF1 POMC PRL
4 neoplasm MP:0002006 8.92 AIP IGF1 POMC PRL

Drugs & Therapeutics for Pituitary Infarct

Search Clinical Trials , NIH Clinical Center for Pituitary Infarct

Genetic Tests for Pituitary Infarct

Anatomical Context for Pituitary Infarct

MalaCards organs/tissues related to Pituitary Infarct:

42
Pituitary, Thyroid, Pancreas, Cortex, Brain, Kidney, Adrenal Gland

Publications for Pituitary Infarct

Articles related to Pituitary Infarct:

(show all 19)
# Title Authors Year
1
Complete pituitary infarction associated with hypothermia and brain death. ( 26971812 )
2016
2
Silent pituitary infarction of an uncommon etiology. ( 25554633 )
2015
3
Pituitary Infarct Masquerading as a Pituitary Abscess. ( 26243170 )
2015
4
A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature. ( 24859515 )
2014
5
Pituitary infarction: a potentially fatal cause of postoperative hyponatraemia and ocular palsy. ( 21415109 )
2011
6
Immunohistochemical expression of nestin in adenohypophysial vessels during development of pituitary infarction. ( 18173320 )
2008
7
Silent pituitary infarction after coronary artery bypass grafting procedure: case report and review of literature. ( 16524865 )
2006
8
Pituitary infarction resulting from intranasal cocaine abuse. ( 16033719 )
2004
9
Amelioration of acromegaly after pituitary infarction due to gastrointestinal hemorrhage from gastric ulcer. ( 10426579 )
1999
10
Sudden headache with pituitary infarction. ( 10595776 )
1999
11
Ectopic release of GHRH and ACTH from an adenoid cystic carcinoma resulting in acromegaly and complicated by pituitary infarction. ( 2845379 )
1988
12
Isolated adrenocorticotropic hormone deficiency with antepartum pituitary infarction in a type I diabetic. ( 2983276 )
1985
13
Pituitary infarction and development of the empty sella syndrome after gastrointestinal haemorrhage. ( 6434032 )
1984
14
Severe diabetic microangiopathy with normal glucose tolerance and pituitary infarction. ( 6414614 )
1983
15
Antepartum pituitary infarction. ( 424120 )
1979
16
Diabetes insipidus and panhypopituitarism after pituitary infarction in a case of acromegaly. ( 890301 )
1977
17
Renal cortical necrosis with pituitary infarction in a nonpregnant woman. ( 5689121 )
1968
18
Amelioration of diabetes mellitus after pituitary infarction. Report of three cases. ( 13827343 )
1960
19
[Postpartum pituitary infarction; Sheehan's syndrome; report of three cases]. ( 13286786 )
1956

Variations for Pituitary Infarct

Expression for Pituitary Infarct

Search GEO for disease gene expression data for Pituitary Infarct.

Pathways for Pituitary Infarct

Pathways related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 POMC PRL

GO Terms for Pituitary Infarct

Cellular components related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 IGF1 POMC PRL SST
2 secretory granule GO:0030141 8.65 POMC

Biological processes related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to heat GO:0009408 9.16 IGF1 SST
2 response to nutrient GO:0007584 9.02 SST
3 positive regulation of epithelial cell proliferation GO:0050679 8.96 IGF1
4 regulation of multicellular organism growth GO:0040014 8.96 IGF1 PRL
5 regulation of signaling receptor activity GO:0010469 8.92 IGF1 POMC PRL SST

Molecular functions related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.92 IGF1 POMC PRL SST

Sources for Pituitary Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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