MCID: PTT010
MIFTS: 25

Pituitary Infarct

Categories: Endocrine diseases

Aliases & Classifications for Pituitary Infarct

MalaCards integrated aliases for Pituitary Infarct:

Name: Pituitary Infarct 12 15
Pituitary Infarction 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1130
NCIt 50 C27117
SNOMED-CT 68 95830009
UMLS 73 C0342405

Summaries for Pituitary Infarct

MalaCards based summary : Pituitary Infarct, also known as pituitary infarction, is related to diabetes insipidus and acromegaly. An important gene associated with Pituitary Infarct is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Pituitary Infarct

Diseases related to Pituitary Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 diabetes insipidus 29.6 POMC PRL
2 acromegaly 27.9 IGF1 POMC PRL SST
3 empty sella syndrome 27.5 GNRH1 IGF1 POMC PRL
4 adenohypophysitis 10.3 POMC PRL
5 sella turcica neoplasm 10.3 POMC PRL
6 tuberculum sellae meningioma 10.3 POMC PRL
7 acth-secreting pituitary adenoma 10.2 POMC PRL
8 fasting hypoglycemia 10.2 IGF1 POMC
9 galactorrhea 10.2 IGF1 PRL
10 persistent fetal circulation syndrome 10.2 IGF1 POMC
11 pseudohypoparathyroidism, type ia 10.2 IGF1 PRL
12 bronchus adenoma 10.2 POMC SST
13 opiate dependence 10.2 IGF1 POMC
14 gynecomastia 10.2 POMC PRL
15 mammographic density 10.2 IGF1 PRL
16 ectopic cushing syndrome 10.1 POMC SST
17 tsh producing pituitary tumor 10.1 PRL SST
18 acanthosis nigricans 10.1 IGF1 PRL
19 chronic fatigue syndrome 10.1 IGF1 POMC
20 hormone producing pituitary cancer 10.1 IGF1 SST
21 prolactin producing pituitary tumor 10.1 PRL SST
22 overnutrition 10.0 IGF1 POMC
23 growth hormone secreting pituitary adenoma 10.0 PRL SST
24 carcinoid syndrome 10.0 IGF1 SST
25 breast disease 10.0 IGF1 PRL
26 short bowel syndrome 10.0 IGF1 SST
27 microvascular complications of diabetes 1 10.0 IGF1 SST
28 endometriosis of uterus 9.9 GNRH1 PRL
29 adrenal rest tumor 9.9 GNRH1 POMC
30 hypogonadotropism 9.9 GNRH1 PRL
31 endogenous depression 9.8 GNRH1 POMC
32 insulin-like growth factor i 9.8 IGF1 PRL
33 central precocious puberty 9.8 GNRH1 IGF1
34 hyperthyroidism 9.8 PRL SST
35 multiple endocrine neoplasia, type i 9.8 PRL SST
36 sheehan syndrome 9.7 IGF1 POMC PRL
37 hypothyroidism, congenital, nongoitrous, 4 9.7 IGF1 POMC PRL
38 thyroid carcinoma, familial medullary 9.7 POMC SST
39 central nervous system organ benign neoplasm 9.7 IGF1 POMC PRL
40 varicocele 9.7 GNRH1 PRL
41 pituitary hormone deficiency, combined, 2 9.7 IGF1 POMC PRL
42 thyroid gland disease 9.7 IGF1 POMC PRL
43 robinow syndrome 9.7 GNRH1 IGF1
44 anorexia nervosa 9.7 IGF1 POMC PRL
45 male reproductive organ cancer 9.7 GNRH1 IGF1
46 reproductive system disease 9.7 GNRH1 PRL
47 acidophil adenoma 9.6 IGF1 POMC SST
48 hypothyroidism 9.6 IGF1 POMC PRL
49 pituitary carcinoma 9.6 POMC PRL SST
50 nelson syndrome 9.6 POMC PRL SST

Graphical network of the top 20 diseases related to Pituitary Infarct:



Diseases related to Pituitary Infarct

Symptoms & Phenotypes for Pituitary Infarct

MGI Mouse Phenotypes related to Pituitary Infarct:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.72 GNRH1 IGF1 POMC PRL SST
2 immune system MP:0005387 9.65 GNRH1 IGF1 POMC PRL SST
3 integument MP:0010771 9.46 GNRH1 IGF1 POMC PRL
4 neoplasm MP:0002006 9.26 GNRH1 IGF1 POMC PRL
5 nervous system MP:0003631 9.02 GNRH1 IGF1 POMC PRL SST

Drugs & Therapeutics for Pituitary Infarct

Search Clinical Trials , NIH Clinical Center for Pituitary Infarct

Genetic Tests for Pituitary Infarct

Anatomical Context for Pituitary Infarct

MalaCards organs/tissues related to Pituitary Infarct:

41
Pituitary

Publications for Pituitary Infarct

Articles related to Pituitary Infarct:

# Title Authors Year
1
Pituitary Infarct Masquerading as a Pituitary Abscess. ( 26243170 )
2015
2
Immunohistochemical expression of nestin in adenohypophysial vessels during development of pituitary infarction. ( 18173320 )
2008
3
Pituitary infarction resulting from intranasal cocaine abuse. ( 16033719 )
2004
4
Pituitary infarction and development of the empty sella syndrome after gastrointestinal haemorrhage. ( 6434032 )
1984
5
Diabetes insipidus and panhypopituitarism after pituitary infarction in a case of acromegaly. ( 890301 )
1977

Variations for Pituitary Infarct

Expression for Pituitary Infarct

Search GEO for disease gene expression data for Pituitary Infarct.

Pathways for Pituitary Infarct

GO Terms for Pituitary Infarct

Cellular components related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 GNRH1 IGF1 POMC PRL SST
2 extracellular space GO:0005615 9.02 GNRH1 IGF1 POMC PRL SST

Biological processes related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glucose homeostasis GO:0042593 9.43 IGF1 POMC
2 cell-cell signaling GO:0007267 9.43 GNRH1 POMC SST
3 female pregnancy GO:0007565 9.4 GNRH1 PRL
4 response to nutrient levels GO:0031667 9.37 IGF1 PRL
5 response to heat GO:0009408 9.32 IGF1 SST
6 response to steroid hormone GO:0048545 9.16 GNRH1 SST
7 regulation of signaling receptor activity GO:0010469 9.02 GNRH1 IGF1 POMC PRL SST
8 regulation of multicellular organism growth GO:0040014 8.96 IGF1 PRL

Molecular functions related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 GNRH1 IGF1 POMC PRL SST

Sources for Pituitary Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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