MCID: PTT010
MIFTS: 30

Pituitary Infarct

Categories: Endocrine diseases

Aliases & Classifications for Pituitary Infarct

MalaCards integrated aliases for Pituitary Infarct:

Name: Pituitary Infarct 12 15
Pituitary Infarction 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1130
NCIt 50 C27117
SNOMED-CT 68 95830009
UMLS 73 C0342405

Summaries for Pituitary Infarct

MalaCards based summary : Pituitary Infarct, also known as pituitary infarction, is related to diabetes insipidus and acromegaly. An important gene associated with Pituitary Infarct is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, lung and kidney, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Pituitary Infarct

Diseases related to Pituitary Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
# Related Disease Score Top Affiliating Genes
1 diabetes insipidus 29.7 POMC PRL
2 acromegaly 29.4 IGF1 POMC PRL SST
3 empty sella syndrome 29.0 GNRH1 IGF1 POMC PRL
4 adenohypophysitis 10.1 POMC PRL
5 sella turcica neoplasm 10.1 POMC PRL
6 tuberculum sellae meningioma 10.1 POMC PRL
7 acth-secreting pituitary adenoma 10.1 POMC PRL
8 fasting hypoglycemia 10.1 IGF1 POMC
9 abducens nerve disease 10.1 POMC PRL
10 galactorrhea 10.1 IGF1 PRL
11 pseudohypoparathyroidism, type ia 10.1 IGF1 PRL
12 bronchus adenoma 10.1 POMC SST
13 bronchial adenomas/carcinoids childhood 10.1 POMC SST
14 opiate dependence 10.1 IGF1 POMC
15 gynecomastia 10.1 POMC PRL
16 mammographic density 10.1 IGF1 PRL
17 pancreatic endocrine carcinoma 10.0 POMC SST
18 fibromyalgia 10.0 IGF1 PRL
19 chronic fatigue syndrome 10.0 IGF1 POMC
20 ectopic cushing syndrome 10.0 POMC SST
21 hormone producing pituitary cancer 10.0 IGF1 SST
22 prolactin producing pituitary tumor 10.0 PRL SST
23 adrenal gland disease 10.0 POMC SST
24 acanthosis nigricans 10.0 IGF1 PRL
25 overnutrition 10.0 IGF1 POMC
26 growth hormone secreting pituitary adenoma 10.0 PRL SST
27 spinocerebellar degeneration 10.0 PRL SST
28 carcinoid syndrome 10.0 IGF1 SST
29 endocrine pancreas disease 10.0 IGF1 SST
30 isolated growth hormone deficiency, type ii 10.0 IGF1 SST
31 short bowel syndrome 10.0 IGF1 SST
32 hypogonadotropism 10.0 GNRH1 PRL
33 central precocious puberty 9.9 GNRH1 IGF1
34 hyperthyroidism 9.9 PRL SST
35 pelvic varices 9.9 GNRH1 PRL
36 microvascular complications of diabetes 1 9.9 IGF1 SST
37 thyroid carcinoma, familial medullary 9.9 POMC SST
38 multiple endocrine neoplasia, type i 9.9 PRL SST
39 sheehan syndrome 9.9 IGF1 POMC PRL
40 hypothyroidism, congenital, nongoitrous, 4 9.9 IGF1 POMC PRL
41 adenomyosis 9.9 GNRH1 PRL
42 hypothyroidism 9.9 IGF1 POMC PRL
43 varicocele 9.9 GNRH1 PRL
44 pituitary hormone deficiency, combined, 2 9.9 IGF1 POMC PRL
45 male reproductive organ cancer 9.9 GNRH1 IGF1
46 anorexia nervosa 9.9 IGF1 POMC PRL
47 robinow syndrome 9.9 GNRH1 IGF1
48 breast disease 9.9 IGF1 POMC PRL
49 male reproductive system disease 9.9 GNRH1 IGF1
50 thyroid cancer, nonmedullary, 2 9.9 POMC SST

Graphical network of the top 20 diseases related to Pituitary Infarct:



Diseases related to Pituitary Infarct

Symptoms & Phenotypes for Pituitary Infarct

MGI Mouse Phenotypes related to Pituitary Infarct:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.72 GNRH1 IGF1 POMC PRL SST
2 immune system MP:0005387 9.65 GNRH1 IGF1 POMC PRL SST
3 integument MP:0010771 9.46 GNRH1 IGF1 POMC PRL
4 neoplasm MP:0002006 9.26 GNRH1 IGF1 POMC PRL
5 nervous system MP:0003631 9.02 GNRH1 IGF1 POMC PRL SST

Drugs & Therapeutics for Pituitary Infarct

Search Clinical Trials , NIH Clinical Center for Pituitary Infarct

Genetic Tests for Pituitary Infarct

Anatomical Context for Pituitary Infarct

MalaCards organs/tissues related to Pituitary Infarct:

41
Pituitary, Lung, Kidney, Pancreas, Thyroid, Cortex, Adrenal Gland

Publications for Pituitary Infarct

Articles related to Pituitary Infarct:

(show all 19)
# Title Authors Year
1
Complete pituitary infarction associated with hypothermia and brain death. ( 26971812 )
2016
2
Pituitary Infarct Masquerading as a Pituitary Abscess. ( 26243170 )
2015
3
Silent pituitary infarction of an uncommon etiology. ( 25554633 )
2015
4
A rare case of pituitary infarction leading to spontaneous tumour resolution and CSF-sella syndrome in an 11-year-old girl and a review of the paediatric literature. ( 24859515 )
2014
5
Pituitary infarction: a potentially fatal cause of postoperative hyponatraemia and ocular palsy. ( 21415109 )
2011
6
Immunohistochemical expression of nestin in adenohypophysial vessels during development of pituitary infarction. ( 18173320 )
2008
7
Silent pituitary infarction after coronary artery bypass grafting procedure: case report and review of literature. ( 16524865 )
2006
8
Pituitary infarction resulting from intranasal cocaine abuse. ( 16033719 )
2004
9
Amelioration of acromegaly after pituitary infarction due to gastrointestinal hemorrhage from gastric ulcer. ( 10426579 )
1999
10
Sudden headache with pituitary infarction. ( 10595776 )
1999
11
Ectopic release of GHRH and ACTH from an adenoid cystic carcinoma resulting in acromegaly and complicated by pituitary infarction. ( 2845379 )
1988
12
Isolated adrenocorticotropic hormone deficiency with antepartum pituitary infarction in a type I diabetic. ( 2983276 )
1985
13
Pituitary infarction and development of the empty sella syndrome after gastrointestinal haemorrhage. ( 6434032 )
1984
14
Severe diabetic microangiopathy with normal glucose tolerance and pituitary infarction. ( 6414614 )
1983
15
Antepartum pituitary infarction. ( 424120 )
1979
16
Diabetes insipidus and panhypopituitarism after pituitary infarction in a case of acromegaly. ( 890301 )
1977
17
Renal cortical necrosis with pituitary infarction in a nonpregnant woman. ( 5689121 )
1968
18
Amelioration of diabetes mellitus after pituitary infarction. Report of three cases. ( 13827343 )
1960
19
[Postpartum pituitary infarction; Sheehan's syndrome; report of three cases]. ( 13286786 )
1956

Variations for Pituitary Infarct

Expression for Pituitary Infarct

Search GEO for disease gene expression data for Pituitary Infarct.

Pathways for Pituitary Infarct

GO Terms for Pituitary Infarct

Cellular components related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 GNRH1 IGF1 POMC PRL SST
2 secretory granule GO:0030141 9.16 POMC PRL
3 extracellular space GO:0005615 9.02 GNRH1 IGF1 POMC PRL SST

Biological processes related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to ethanol GO:0045471 9.48 GNRH1 PRL
2 female pregnancy GO:0007565 9.46 GNRH1 PRL
3 response to nutrient GO:0007584 9.43 PRL SST
4 positive regulation of epithelial cell proliferation GO:0050679 9.4 IGF1 PRL
5 response to heat GO:0009408 9.37 IGF1 SST
6 cell-cell signaling GO:0007267 9.33 GNRH1 POMC SST
7 response to steroid hormone GO:0048545 9.32 GNRH1 SST
8 regulation of multicellular organism growth GO:0040014 9.26 IGF1 PRL
9 regulation of signaling receptor activity GO:0010469 9.02 GNRH1 IGF1 POMC PRL SST
10 ovulation cycle GO:0042698 8.96 GNRH1 PRL

Molecular functions related to Pituitary Infarct according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 GNRH1 IGF1 POMC PRL SST

Sources for Pituitary Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
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45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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