MCID: PTY004
MIFTS: 26

Pityriasis Lichenoides

Categories: Rare diseases

Aliases & Classifications for Pityriasis Lichenoides

MalaCards integrated aliases for Pityriasis Lichenoides:

Name: Pityriasis Lichenoides 53 73

Classifications:



External Ids:

UMLS 73 C0162853

Summaries for Pityriasis Lichenoides

NIH Rare Diseases : 53 Pityriasis lichenoides (PL) is a skin condition characterized by small, raised pink spots that tend to come together in groups. It is not contagious. There are two main types of PL: an acute form called pityriasis lichenoides et varioliformis acuta (PLEVA), and a milder, longer-lasting form called pityriasis lichenoides chronica (PLC). There is also a rare, severe variant of PLEVA called febrile ulceronecrotic PLEVA, associated with high fever and complications that may affect other body systems. In both types of PL, spots usually occur on the trunk, buttox, arms and legs. PLEVA begins abruptly and may cause itching or burning. PLC may develop over days, is less irritating, and lasts longer than PLEVA. Spots associated with PLC typically fade within 3 to 4 weeks, but new spots may then appear. There is no clear consensus regarding how long either form of PL lasts, but most cases resolve on their own within one to several months. Some cases may wax and wane, or relapse over a period of years. The cause of PL is not known. Theories on the cause have included the possibility of a low-grade or self-limited lymphoproliferative disorder; a reaction to a bacterial or viral infection; and an inappropriate, inflammatory immune response to an unknown foreign agent. Treatment options may include antibiotics, phototherapy, PUVA, or medications that suppress the immune system response (immunosuppressants) in severe cases.

MalaCards based summary : Pityriasis Lichenoides is related to pityriasis lichenoides et varioliformis acuta and lichen nitidus. An important gene associated with Pityriasis Lichenoides is MS4A1 (Membrane Spanning 4-Domains A1), and among its related pathways/superpathways are Hematopoietic cell lineage and B Cell Development Pathways. Affiliated tissues include skin, t cells and tongue.

Wikipedia : 76 Pityriasis lichenoides is a form of... more...

Related Diseases for Pityriasis Lichenoides

Diseases related to Pityriasis Lichenoides via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 pityriasis lichenoides et varioliformis acuta 33.6 CD7 TNFRSF8
2 lichen nitidus 30.0 MX1 TNFRSF8
3 mycosis fungoides 29.6 CD7 TNFRSF8
4 lymphoma, non-hodgkin, familial 29.2 MS4A1 TNFRSF8
5 pityriasis lichenoides chronica 12.7
6 febrile ulceronecrotic mucha-habermann disease 11.5
7 lymphomatoid papulosis 10.4
8 lymphoma 10.4
9 parapsoriasis 10.3
10 cutaneous t cell lymphoma 10.2
11 psoriasis 10.1
12 toxoplasmosis 10.1
13 secondary syphilis 10.1
14 syphilis 10.1
15 mumps 10.0
16 measles 10.0
17 hypersensitivity reaction type iii disease 10.0
18 rubella 10.0
19 hepatitis 10.0
20 peripheral t-cell lymphoma 9.9 MS4A1 TNFRSF8
21 connective tissue disease 9.8
22 maculopapular cutaneous mastocytosis 9.8
23 psoriasis 7 9.8
24 influenza 9.8
25 neurosyphilis 9.8
26 severe cutaneous adverse reaction 9.8
27 hand, foot and mouth disease 9.8
28 herpes simplex 9.8
29 psoriasis 11 9.8
30 urticaria pigmentosa 9.8
31 psoriasis 13 9.8
32 urticaria 9.8
33 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.8
34 autoimmune lymphoproliferative syndrome, type v 9.8
35 vasculitis 9.8
36 alopecia 9.8
37 lymphadenitis 9.8
38 arthritis 9.8
39 keratosis 9.8
40 pityriasis rosea 9.8
41 keratitis-ichthyosis-deafness syndrome, autosomal dominant 9.8
42 autoimmune hepatitis 9.8
43 ichthyosis 9.8
44 lichen sclerosus et atrophicus 9.8
45 common variable immunodeficiency 9.8
46 hepatitis c 9.8
47 rheumatoid arthritis 9.8
48 crohn's disease 9.8
49 melanoma 9.8
50 alopecia areata 9.8

Graphical network of the top 20 diseases related to Pityriasis Lichenoides:



Diseases related to Pityriasis Lichenoides

Symptoms & Phenotypes for Pityriasis Lichenoides

Drugs & Therapeutics for Pityriasis Lichenoides

Search Clinical Trials , NIH Clinical Center for Pityriasis Lichenoides

Genetic Tests for Pityriasis Lichenoides

Anatomical Context for Pityriasis Lichenoides

MalaCards organs/tissues related to Pityriasis Lichenoides:

41
Skin, T Cells, Tongue

Publications for Pityriasis Lichenoides

Articles related to Pityriasis Lichenoides:

(show top 50) (show all 253)
# Title Authors Year
1
Possible role of plasmacytoid dendritic cells in pityriasis lichenoides. ( 29349807 )
2018
2
Varicella zoster virus as a possible trigger for the development of pityriasis lichenoides et varioliformis acuta: retrospective analysis of our institutional cases. ( 29797478 )
2018
3
Pityriasis lichenoides: Long-term follow-up study. ( 29315771 )
2018
4
Aciclovir for treatment of pityriasis lichenoides? ( 29923208 )
2018
5
Pityriasis Lichenoides, Atypical Pityriasis Lichenoides, and Related Conditions: A Study of 66 Cases. ( 29851705 )
2018
6
Relationship Between Pityriasis Lichenoides and Mycosis Fungoides: A Clinicopathological, Immunohistochemical, and Molecular Study. ( 29210716 )
2017
7
Pityriasis lichenoides-like drug reaction: A clinical histopathologic study of 10 cases. ( 29447634 )
2017
8
Treatment of adult diffuse pityriasis lichenoides chronica with narrowband ultraviolet B: experience and literature review. ( 28111789 )
2017
9
Pityriasis lichenoides et varioliformis acuta in skin of color: new observations by dermoscopy. ( 28243491 )
2017
10
Pityriasis Lichenoides et Varioliformis Acuta and Psoriasis Vulgaris: Mere Coincidence or a Rare Association? ( 28218230 )
2017
11
Systematic Review of Cases of Cutaneous T-Cell Lymphoma Transformation in Pityriasis Lichenoides and Small Plaque Parapsoriasis. ( 27031678 )
2016
12
Pityriasis Lichenoides-like Mycosis Fungoides: Clinical and Histologic Features and Response to Phototherapy. ( 27746631 )
2016
13
Phototherapy for Pityriasis Lichenoides in the Pediatric Population: A Review of the Published Literature. ( 27502793 )
2016
14
Successful treatment of pityriasis lichenoides chronica with narrow-band ultraviolet B therapy in a patient with Keratitis-Ichthyosis-Deafness syndrome: a case report. ( 27617521 )
2016
15
Pityriasis lichenoides chronica responds to minocycline in three patients. ( 27261329 )
2016
16
Pityriasis Lichenoides et Varioliformis Acuta: Remission with Hypopigmentation. ( 27301571 )
2016
17
Pityriasis lichenoides chronica presenting with bilateral palmoplantar involvement. ( 27274548 )
2016
18
Pityriasis lichenoides chronica-like drug eruption developing during pembrolizumab treatment for metastatic melanoma. ( 27570820 )
2016
19
Etanercept-induced pityriasis lichenoides chronica in a patient with rheumatoid arthritis. ( 25789178 )
2015
20
Pityriasis Lichenoides in Childhood: Review of Clinical Presentation and Treatment Options. ( 25816855 )
2015
21
Differentiation of pityriasis lichenoides chronica from guttate psoriasis by dermoscopy. ( 25682853 )
2015
22
Successful therapy of cyclosporin A in pityriasis lichenoides et varioliformis acuta preceded by hand, foot and mouth disease. ( 26669500 )
2015
23
Commentary about papular mycosis fungoides, lymphomatoid papulosis, and lymphomatoid pityriasis lichenoides: More similarities than differences. ( 26566599 )
2015
24
Lichen striatus and pityriasis lichenoides chronica in an 11-year-old girl: An etiologic relationship? ( 26338752 )
2015
25
Adalimumab-Induced Pityriasis Lichenoides Chronica That Responded Well to Methotrexate in a Patient With Psoriasis. ( 26522235 )
2015
26
Pityriasis lichenoides et varioliformis acuta after influenza vaccine. ( 26312710 )
2015
27
Lymphomatoid papulosis misdiagnosed as pityriasis lichenoides et varioliformis acuta: Two case reports and a literature review. ( 25371758 )
2014
28
I^I' T cell-rich variants of pityriasis lichenoides and lymphomatoid papulosis: benign cutaneous disorders to be distinguished from aggressive cutaneous I^I' T cell lymphomas. ( 25143223 )
2014
29
Adult pityriasis lichenoides-like mycosis fungoides: a clinical variant of mycosis fungoides. ( 24961281 )
2014
30
Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) associated with parvovirus infection. ( 23612031 )
2013
31
Is narrowband ultraviolet B monotherapy effective in the treatment of pityriasis lichenoides? ( 23786570 )
2013
32
Pityriasis lichenoides in an Asian population. ( 23488769 )
2013
33
Pityriasis lichenoides-like secondary syphilis and neurosyphilis in a HIV-infected patient. ( 24278062 )
2013
34
Pityriasis lichenoides in a 9-month-old boy. ( 23177392 )
2013
35
Phototherapy for pityriasis lichenoides: our experience. ( 22974328 )
2013
36
Narrow-band UVB phototherapy for pediatric generalized pityriasis lichenoides. ( 24112386 )
2013
37
The relevance of recognizing clinical and morphologic features of pityriasis lichenoides: clinicopathological study of 29 cases. ( 24282656 )
2013
38
Pityriasis lichenoides chronic after measles-mumps-rubella vaccination. ( 21967266 )
2012
39
Pemetrexed-induced pityriasis lichenoides-like dermatitis. ( 22168779 )
2012
40
Pityriasis lichenoides and varioliformis acuta in pregnancy. ( 21470218 )
2012
41
Demonstration of Treponema pallidum by immunohistochemistry in a patient with secondary syphilis mimicking pityriasis lichenoides chronica. ( 22142451 )
2012
42
Childhood pityriasis lichenoides and oral erythromycin. ( 22639857 )
2012
43
Pityriasis lichenoides et varioliformis acuta with numerous CD30(+) cells: a variant mimicking lymphomatoid papulosis and other cutaneous lymphomas. A clinicopathologic, immunohistochemical, and molecular biological study of 13 cases. ( 22472952 )
2012
44
CD8-positive pityriasis lichenoides-like mycosis fungoides. ( 22614934 )
2012
45
Assessment of the 'no eosinophils' rule: are eosinophils truly absent in pityriasis lichenoides, connective tissue disease, and graft-vs.-host disease? ( 22443393 )
2012
46
Pityriasis lichenoides et varioliformis acuta: a rare association with the measles, mumps and rubella vaccine. ( 23157791 )
2012
47
Pityriasis lichenoides. ( 23255714 )
2012
48
Pityriasis lichenoides et varioliformis acuta associated with subcutaneous immunoglobulin administration. ( 22980275 )
2012
49
Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) presenting as Stevens-Johnson syndrome. ( 22084981 )
2012
50
Pityriasis lichenoides chronica associated with use of HMG-CoA reductase inhibitors. ( 23620974 )
2012

Variations for Pityriasis Lichenoides

Expression for Pityriasis Lichenoides

Search GEO for disease gene expression data for Pityriasis Lichenoides.

Pathways for Pityriasis Lichenoides

Pathways related to Pityriasis Lichenoides according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.94 CD7 MS4A1
2 10.35 MS4A1 TNFRSF8

GO Terms for Pityriasis Lichenoides

Biological processes related to Pityriasis Lichenoides according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 8.96 NOS2 TNFRSF8
2 response to lipopolysaccharide GO:0032496 8.62 NOS2 TNFRSF8

Sources for Pityriasis Lichenoides

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69 SNOMED-CT via HPO
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71 TGDB
72 Tocris
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74 UMLS via Orphanet
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