MCID: PTY007
MIFTS: 27

Pityriasis Rotunda

Categories: Cancer diseases, Liver diseases, Rare diseases, Skin diseases

Aliases & Classifications for Pityriasis Rotunda

MalaCards integrated aliases for Pityriasis Rotunda:

Name: Pityriasis Rotunda 20 70

Classifications:



External Ids:

UMLS 70 C0343060

Summaries for Pityriasis Rotunda

GARD : 20 Pityriasis rotunda is a rare skin disease characterized by round, scaly, pigmented patches that mainly occur on the trunk, arms and legs. There are two types of pityriasis rotunda. Type 1 is seen mainly in East/Southeast Asian and South African individuals older than 60 years, and is often associated with internal disease or malignancy ( cancer ). Type 2 occurs in lighter skinned individuals younger than 40 years, and often in several members of the same family. Type 2 pityriasis rotunda is not associated with internal disease or malignancy. The cause of pityriasis rotunda is unknown, but it may be a variant of ichthyosis vulgaris. Type 1 most often occurs with liver and stomach cancer.

MalaCards based summary : Pityriasis Rotunda is related to ichthyosis and ichthyosis, acquired. Affiliated tissues include liver, myeloid and lymph node.

Wikipedia : 73 Pityriasis rotunda is a disorder of keratisation of the skin that manifests as a perfectly circular,... more...

Related Diseases for Pityriasis Rotunda

Diseases related to Pityriasis Rotunda via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 ichthyosis 10.6
2 ichthyosis, acquired 10.5
3 ichthyosis vulgaris 10.5
4 skin disease 10.3
5 dermatophytosis 10.3
6 pityriasis versicolor 10.3
7 myeloma, multiple 10.2
8 exanthem 10.2
9 dowling-degos disease 1 10.0
10 anemia, nonspherocytic hemolytic, due to g6pd deficiency 10.0
11 leukemia, acute myeloid 10.0
12 hyperprolactinemia 10.0
13 tinea cruris 10.0
14 leukemia 10.0
15 dermatomycosis 10.0
16 keratosis 10.0
17 glucosephosphate dehydrogenase deficiency 10.0
18 pulmonary tuberculosis 10.0
19 erythrasma 10.0
20 ovarian cyst 10.0
21 myeloid leukemia 10.0
22 pityriasis rosea 10.0
23 erythrokeratoderma ''en cocardes'' 10.0

Graphical network of the top 20 diseases related to Pityriasis Rotunda:



Diseases related to Pityriasis Rotunda

Symptoms & Phenotypes for Pityriasis Rotunda

Drugs & Therapeutics for Pityriasis Rotunda

Search Clinical Trials , NIH Clinical Center for Pityriasis Rotunda

Genetic Tests for Pityriasis Rotunda

Anatomical Context for Pityriasis Rotunda

MalaCards organs/tissues related to Pityriasis Rotunda:

40
Liver, Myeloid, Lymph Node, Skin

Publications for Pityriasis Rotunda

Articles related to Pityriasis Rotunda:

(show top 50) (show all 68)
# Title Authors PMID Year
1
Pityriasis rotunda. 61
32126584 2020
2
Cutaneous paraneoplastic syndromes. 61
30736994 2019
3
Pityriasis rotunda. A clinical study in Jordan: experience of 10 years. 61
29774541 2018
4
Pityriasis rotunda associated with acute myeloid leukemia. 61
28370261 2018
5
Pityriasis rotunda with recurrent respiratory infections. 61
28166620 2017
6
Pityriasis Rotunda and Hyperprolactinemia. 61
27006018 2016
7
Pityriasis rotunda: a case from Turkey. 61
26695453 2016
8
Decreased filaggrin-2 expression in the epidermis in a case of pityriasis rotunda. 61
26189536 2016
9
When the exception proves the rule: pityriasis rotunda of difficult classification. 61
25208750 2016
10
Pityriasis Rotunda: A Case Report of Familial Disease in an American-Born Black Patient. 61
27065844 2016
11
[Not Available]. 61
26436981 2015
12
Pityriasis rotunda as an incidental paraneoplastic finding in two patients with multiple myeloma. 61
24985090 2014
13
Pityriasis rotunda diagnosed in Canada: case presentation and review of the literature. 61
24138982 2013
14
Chronic hyperpigmented scaly plaques. Pityriasis rotunda (PR). 61
22986863 2012
15
Photoletter to the editor: Pityriasis Rotunda. 61
23091587 2012
16
The profilaggrin N-terminal domain is absent in pityriasis rotunda. 61
21777219 2012
17
Cutaneous paraneoplasia. 61
21855730 2011
18
Diagnosis and treatment of cutaneous paraneoplastic disorders. 61
21054710 2010
19
Paraneoplastic syndromes in patients with primary oral cancers: a systematic review. 61
19833419 2010
20
Pityriasis rotunda. 61
19891922 2009
21
Pityriasis rotunda: sporadic occurrence in an elderly Caucasian patient with diabetes mellitus. 61
19467965 2009
22
Hyperpigmented patches on the trunk of a Nigerian woman. Pityriasis rotunda (PR). 61
19015428 2008
23
Familial pityriasis rotunda in black-skinned patients; a first report. 61
17441953 2007
24
Pityriasis rotunda with low levels of steroid sulfatase. 61
17478393 2007
25
Immunohistological characterization of a Japanese case of pityriasis rotunda. 61
12890220 2003
26
[Acquired circinated ichthyosis revealing a lymph node tuberculosis]. 61
13679702 2003
27
Pityriasis rotunda. 61
17642831 2003
28
Pityriasis rotunda. 61
12546770 2002
29
[Pityriasis rotunda: second Tunisian case]. 61
12534050 2002
30
Pityriasis rotunda in childhood. 61
12047637 2002
31
Case report. Pityriasis versicolor mimicking Pityriasis rotunda. 61
12000517 2002
32
Pityriasis versicolor resembling pityriasis rotunda. 61
11952303 2002
33
Pityriasis rotunda - report of three cases. 61
28615573 2001
34
Pityriasis rotunda mimicking tinea cruris/corporis and erythrasma in an Indian patient. 61
11280467 2001
35
Tinea versicolor mimicking pityriasis rotunda. 61
10671098 1999
36
Pityriasis rotunda. 61
9731975 1998
37
Familial pityriasis rotunda. 61
9111837 1997
38
Pityriasis rotunda: a survey of 42 cases observed in Sardinia, Italy. 61
9031788 1997
39
Pityriasis rotunda. 61
8970778 1996
40
Pityriasis rotunda in Tanzania. 61
8949456 1996
41
Cutaneous paraneoplastic syndromes in solid tumors. 61
7503090 1995
42
Pityriasis rotunda: report of a familial occurrence and review of the literature. 61
7962738 1994
43
[Pityriasis rotunda]. 61
8239376 1993
44
Acquired ichthyosis and pityriasis rotunda. 61
8339196 1993
45
[Pityriasis rotunda. Review of the literature]. 61
8239381 1993
46
Pityriasis rotunda and G6PD deficiency. 61
1399210 1992
47
Pigmented lesions in a patient with pulmonary tuberculosis. Pityriasis rotunda. 61
1863086 1991
48
Pityriasis rotunda associated with multiple myeloma. 61
2007688 1991
49
Familial pityriasis rotunda. 61
2228374 1990
50
Pityriasis rotunda in a Caucasian woman from the Mediterranean area. 61
2591101 1989

Variations for Pityriasis Rotunda

Cosmic variations for Pityriasis Rotunda:

9 (show top 50) (show all 15862)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM122741017 TP53 skin,trunk,carcinoma,NS c.440G>A p.G147E 17:7673784-7673784 6
2 COSM144087146 TP53 skin,arm,carcinoma,NS c.245C>T p.S82F 17:7674241-7674241 6
3 COSM88173893 TP53 skin,leg,carcinoma,NS c.987C>A p.T329= 17:7673541-7673541 6
4 COSM143944147 TP53 skin,arm,carcinoma,NS c.265C>T p.R89W 17:7674221-7674221 6
5 COSM122271260 TP53 skin,upper extremity,carcinoma,NS c.422G>A p.R141H 17:7673802-7673802 6
6 COSM144310575 TP53 skin,leg,carcinoma,NS c.443-1G>A p.? 17:7674972-7674972 6
7 COSM87897745 TP53 skin,leg,carcinoma,NS c.524G>A p.R175H 17:7675088-7675088 6
8 COSM144650780 TP53 skin,leg,carcinoma,NS c.407G>A p.R136H 17:7675088-7675088 6
9 COSM88272290 TP53 skin,trunk,carcinoma,NS c.480G>C p.M160I 17:7675132-7675132 6
10 COSM142560684 TP53 skin,leg,carcinoma,NS c.443-1G>A p.? 17:7674972-7674972 6
11 COSM143944858 TP53 skin,trunk,carcinoma,NS c.109C>T p.R37* 17:7674945-7674945 6
12 COSM143964140 TP53 skin,leg,carcinoma,NS c.386A>G p.N129S 17:7673757-7673757 6
13 COSM143156879 TP53 skin,trunk,carcinoma,NS c.245C>T p.S82F 17:7674241-7674241 6
14 COSM143182032 TP53 skin,leg,carcinoma,NS c.263A>T p.N88I 17:7674223-7674223 6
15 COSM144316210 TP53 skin,trunk,carcinoma,NS c.716C>T p.P239L 17:7673787-7673787 6
16 COSM142842830 TP53 skin,leg,carcinoma,NS c.833C>T p.P278L 17:7673787-7673787 6
17 COSM106455733 TP53 skin,trunk,carcinoma,NS c.853G>C p.E285Q 17:7673767-7673767 6
18 COSM112283184 TP53 skin,arm,carcinoma,NS c.859G>A p.E287K 17:7673761-7673761 6
19 COSM143157606 TP53 skin,trunk,carcinoma,NS c.109C>T p.R37* 17:7674945-7674945 6
20 COSM143157097 TP53 skin,leg,carcinoma,NS c.83-1G>A p.? 17:7674972-7674972 6
21 COSM144310437 TP53 skin,trunk,carcinoma,NS c.727C>T p.R243W 17:7673776-7673776 6
22 COSM112571322 TP53 skin,trunk,carcinoma,NS c.480G>C p.M160I 17:7675132-7675132 6
23 COSM112253674 TP53 skin,trunk,carcinoma,NS c.722C>T p.S241F 17:7674241-7674241 6
24 COSM142845131 TP53 skin,trunk,carcinoma,NS c.832C>T p.P278S 17:7673788-7673788 6
25 COSM106489100 TP53 skin,arm,carcinoma,NS c.899C>G p.P300R 17:7673721-7673721 6
26 COSM106283528 TP53 skin,leg,carcinoma,NS c.987C>A p.T329= 17:7673541-7673541 6
27 COSM121875541 TP53 skin,upper extremity,carcinoma,NS c.422G>A p.R141H 17:7673802-7673802 6
28 COSM121985820 TP53 skin,trunk,carcinoma,NS c.226G>T p.D76Y 17:7674909-7674909 6
29 COSM143753198 TP53 skin,trunk,carcinoma,NS c.736G>C p.E246Q 17:7673767-7673767 6
30 COSM111766512 TP53 skin,trunk,carcinoma,NS c.836G>A p.G279E 17:7673784-7673784 6
31 COSM111982907 TP53 skin,leg,carcinoma,NS c.987C>A p.T329= 17:7673541-7673541 6
32 COSM87934170 TP53 skin,leg,carcinoma,NS c.740A>T p.N247I 17:7674223-7674223 6
33 COSM144110316 TP53 skin,leg,carcinoma,NS c.263A>T p.N88I 17:7674223-7674223 6
34 COSM122069813 TP53 skin,leg,carcinoma,NS c.286G>A p.D96N 17:7674281-7674281 6
35 COSM143950269 TP53 skin,leg,carcinoma,NS c.356C>T p.P119L 17:7673787-7673787 6
36 COSM111758565 TP53 skin,arm,carcinoma,NS c.829T>G p.C277G 17:7673791-7673791 6
37 COSM142838067 TP53 skin,trunk,carcinoma,NS c.586C>T p.R196* 17:7674945-7674945 6
38 COSM105621487 TP53 skin,leg,carcinoma,NS c.586C>T p.R196* 17:7674945-7674945 6
39 COSM112438522 TP53 skin,leg,carcinoma,NS c.682G>A p.D228N 17:7674281-7674281 6
40 COSM93191448 TP53 skin,trunk,carcinoma,NS c.833C>T p.P278L 17:7673787-7673787 6
41 COSM144310268 TP53 skin,leg,carcinoma,NS c.419A>G p.H140R 17:7675076-7675076 6
42 COSM123142151 TP53 skin,trunk,carcinoma,NS c.457G>C p.E153Q 17:7673767-7673767 6
43 COSM122272676 TP53 skin,trunk,carcinoma,NS c.190C>T p.R64* 17:7674945-7674945 6
44 COSM111788413 TP53 skin,arm,carcinoma,NS c.859G>A p.E287K 17:7673761-7673761 6
45 COSM112260509 TP53 skin,leg,carcinoma,NS c.833C>T p.P278L 17:7673787-7673787 6
46 COSM122271863 TP53 skin,leg,carcinoma,NS c.311A>G p.Y104C 17:7674256-7674256 6
47 COSM144311120 TP53 skin,trunk,carcinoma,NS c.469C>T p.R157* 17:7674945-7674945 6
48 COSM122734234 TP53 skin,arm,carcinoma,NS c.326C>T p.S109F 17:7674241-7674241 6
49 COSM144103755 TP53 skin,trunk,carcinoma,NS c.589G>T p.D197Y 17:7674909-7674909 6
50 COSM112304734 TP53 skin,trunk,carcinoma,NS c.737T>G p.M246R 17:7674226-7674226 6

Expression for Pityriasis Rotunda

Search GEO for disease gene expression data for Pityriasis Rotunda.

Pathways for Pityriasis Rotunda

GO Terms for Pityriasis Rotunda

Sources for Pityriasis Rotunda

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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