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MIFTS: 45

Placenta Accreta

Categories: Fetal diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Placenta Accreta

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MalaCards integrated aliases for Placenta Accreta:

Name: Placenta Accreta 12 44 15 73

Classifications:

MalaCards categories:
Global: Fetal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4744
ICD10 33 O43.21
MeSH 44 D010921
NCIt 50 C26856
SNOMED-CT 68 70129008
UMLS 73 C0032044
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Summaries for Placenta Accreta

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Disease Ontology : 12 A placenta disease that is characterized by an abnormally deep attachment of the placenta, through the endometrium and into the myometrium.

MalaCards based summary : Placenta Accreta is related to placenta disease and placental abruption. An important gene associated with Placenta Accreta is ANGPT2 (Angiopoietin 2), and among its related pathways/superpathways are ERK Signaling and TGF-Beta Pathway. The drugs Tranexamic Acid and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include placenta, uterus and ovary, and related phenotypes are Increased senescence-associated beta-galactosidase protein expression after pRB stimulation and cardiovascular system

Wikipedia : 76 Placenta accreta occurs when all or part of the placenta attaches abnormally to the myometrium (the... more...

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Related Diseases for Placenta Accreta

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Diseases related to Placenta Accreta via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 placenta disease 30.6 CGB3 PGF
2 placental abruption 30.0 FLT1 PGF
3 pulmonary hypertension 27.7 ANGPT1 FLT1 PGF SERPINE1 TEK
4 placenta praevia 11.5
5 cervicitis 10.3
6 asherman's syndrome 10.3
7 vaginitis 10.2
8 mild pre-eclampsia 10.2 FLT1 PGF
9 epithelioid hemangioendothelioma 10.2 FLT1 PGF
10 macrophage activation syndrome 10.2 ANGPT1 ANGPT2
11 cancer-associated retinopathy 10.1 FLT1 PGF
12 chronic myocardial ischemia 10.1 ANGPT1 TEK
13 gestational trophoblastic neoplasm 10.1
14 intramuscular hemangioma 10.1 ANGPT1 TEK
15 limb ischemia 10.1 ANGPT2 PGF TEK
16 corneal neovascularization 10.1 FLT1 TEK
17 hydatidiform mole, recurrent, 1 10.0
18 chorioamnionitis 10.0
19 disseminated intravascular coagulation 10.0
20 trophoblastic neoplasm 10.0
21 uterine inversion 10.0
22 endotheliitis 10.0
23 adenosquamous pancreas carcinoma 10.0 ANGPT1 TEK
24 ectopic pregnancy 10.0 CGB3 PGF
25 adult respiratory distress syndrome 9.9 ANGPT2 SERPINB2 SERPINE1
26 angiosarcoma 9.9 FLT1 TEK
27 exudative vitreoretinopathy 1 9.9 ANGPT2 FLT1 TEK
28 atrial standstill 1 9.9
29 uterine anomalies 9.9
30 wolff-parkinson-white syndrome 9.9
31 aging 9.9
32 sickle cell anemia 9.9
33 preterm premature rupture of the membranes 9.9
34 blood group, cromer system 9.9
35 arteriovenous fistula 9.9
36 thrombosis 9.9
37 arteriovenous malformation 9.9
38 gestational diabetes 9.9
39 choriocarcinoma 9.9
40 placental site trophoblastic tumor 9.9
41 syphilis 9.9
42 pulmonary embolism 9.9
43 myotonic dystrophy 9.9
44 limb-body wall complex 9.9
45 myotonia atrophica 9.9
46 partial hydatidiform mole 9.9
47 pyogenic granuloma 9.8 ANGPT1 ANGPT2 TEK
48 microvascular complications of diabetes 1 9.8 ANGPT2 FLT1
49 hellp syndrome 9.7 FLT1 PGF SERPINE1
50 epileptic encephalopathy, childhood-onset 9.7 ANGPT1 ANGPT2 SERPINE1

Graphical network of the top 20 diseases related to Placenta Accreta:



Diseases related to Placenta Accreta
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Symptoms & Phenotypes for Placenta Accreta

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GenomeRNAi Phenotypes related to Placenta Accreta according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased senescence-associated beta-galactosidase protein expression after pRB stimulation GR00230-A-2 8.62 FLT1 TEK

MGI Mouse Phenotypes related to Placenta Accreta:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.63 ANGPT1 ANGPT2 FLT1 PGF SERPINE1 TEK
2 homeostasis/metabolism MP:0005376 9.5 TEK ANGPT1 ANGPT2 FLT1 PGF SERPINB2
3 vision/eye MP:0005391 9.02 TEK ANGPT1 ANGPT2 FLT1 PGF
Sources

Drugs & Therapeutics for Placenta Accreta

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Drugs for Placenta Accreta (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tranexamic Acid Approved Phase 4,Phase 3 1197-18-8 5526
2 Coagulants Phase 4,Phase 3
3 Hemostatics Phase 4,Phase 3
4 Antifibrinolytic Agents Phase 4,Phase 3
5
Mannitol Approved, Investigational Phase 3 69-65-8 453 6251
6 penicillins Phase 3
7 Anesthetics Phase 3
8 Pharmaceutical Solutions Phase 3
9
Letrozole Approved, Investigational Not Applicable 112809-51-5 3902
10
Progesterone Approved, Vet_approved Not Applicable 57-83-0 5994
11
Menotropins Approved Not Applicable 61489-71-2, 9002-68-0 5360545
12
Creatine Approved, Investigational, Nutraceutical 57-00-1 586
13 Deslorelin Investigational, Vet_approved Not Applicable 57773-65-6
14 Steroid Synthesis Inhibitors Not Applicable
15 Hormone Antagonists Not Applicable
16 Hormones Not Applicable
17 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
18 Estrogen Antagonists Not Applicable
19 Estrogens Not Applicable
20 Aromatase Inhibitors Not Applicable
21 acivicin
22 Fertility Agents Not Applicable
23 Chorionic Gonadotropin Not Applicable
24 Vasopressins Not Applicable
25 Arginine Vasopressin Not Applicable

Interventional clinical trials:

(show all 42)
# Name Status NCT ID Phase Drugs
1 Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta Study Recruiting NCT02806024 Phase 4 Tranexamic Acid;Placebo Drug
2 Tranexamic Acid in Adherent Placenta (TAP) Not yet recruiting NCT02329756 Phase 3 Tranexamic Acid (TXA);Sodium Chloride 0.9%
3 Emergency Peripartum Hysterectomy: A Prospective Study in Iran Completed NCT01285258 Phase 2
4 Placenta Accreta&Its Complications in Placenta Previa Cases Unknown status NCT02606474
5 Cell-free Fetal DNA Circulating in the Maternal Plasma as a Marker for Morbidly Adherent Placenta Unknown status NCT02784886
6 Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome Unknown status NCT01805102
7 Letrozole Versus Chinese Herbal Medicine on Polycystic Ovary Syndrome (PCOS) Unknown status NCT01431352 Not Applicable Letrozole;Chinese herbal medicine granules or Chinese herbal medicine granules placebo
8 Placenta Accreta : Contrast-enhanced Ultrasound Analysis in High Risk Population Completed NCT02302573 Not Applicable contast-enhanced ultrasound with sonovue
9 Clinical Situations at High Risk of Placenta Accreta / Percreta Completed NCT02010229
10 TUI 3D in Diagnosis of Placenta Accreta: Comparison With Gray-scale and Color Doppler Techniques Completed NCT02712099
11 Comparison Between Hysterectomy and Conservative Management in Treatment of Placenta Accreta Regarding Maternal Complication Completed NCT03327818
12 Transverse B-Lynch in Management of Placenta Accreta Completed NCT02943421
13 Balloon Catheters in Cases of Abnormal Placentation Completed NCT01373255 Not Applicable
14 Efficacy of Prophylactic Internal Iliac Artery Balloon Catheterization in the Management of Placenta Previa and Accreta Completed NCT02966197 Not Applicable
15 Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure Completed NCT01289262 Not Applicable
16 The Placenta Previa and Fetal Weight Completed NCT03321435
17 Internal Iliac Artery Ligation and Abnormally Invasive Placenta Completed NCT02728232 Not Applicable
18 The Effectiveness of Double Incision Technique in Uterus Preserving Surgery for Placenta Percreta Completed NCT02702024 Not Applicable
19 Optimization of the Healing Process of the Uterine Scar Tissue After Re-cesarean Section Completed NCT02703519 Not Applicable
20 Early Prediction of Placenta Accreta by Ultrasound and Color Doppler Recruiting NCT03032770
21 Surgical Technique To Control Postpartum Hemorrhage Recruiting NCT03241849 Not Applicable
22 Reducing Blood Loss During Cesarean Hysterectomy for Placenta Accreta Spectrum Recruiting NCT03570710 Not Applicable intravenous tranexamic acid;Topical tranexamic acid;Normal saline
23 Creatine Kinase Versus 3D Doppler for Antenatal Diagnosis of Abnormal Adherent Placenta. Recruiting NCT03224780
24 Antenatal Diagnosis of Placental Attachment Disorders Recruiting NCT02442518
25 Comparison Between the Role of Transabdominal Ultrasound Versus Transvaginal Ultrasound in Evaluation of Placental Invasion in Cases of Placenta Previa Anterior Wall With Previous Uterine Scar Recruiting NCT03437291
26 Role of Ultrasound in Diagnosis of Placenta Previa and MAP Recruiting NCT03416296
27 Uterine Cavity and Blood Flow After Conservative Management of Placenta Previa/Accreta Recruiting NCT02878187
28 Predictors of Scar Dehiscence in Patients With Previous Caesarean Section Recruiting NCT03140683
29 Transfusion of Whole Blood and Cesarean Delivery Recruiting NCT03523780
30 Fertility Post Placenta Accrete Recruiting NCT02821702 Not Applicable
31 ICSI Versus Conventional IVF in Non-male Factor Couples Recruiting NCT03428919 Not Applicable
32 IVM Versus IVF in High Antral Follicle Count Patients Recruiting NCT03405701 Not Applicable
33 NIche Development With Closure of Cesarean Uterotomy by Modified or Conventional Two-layer Technique Active, not recruiting NCT02410395 Not Applicable
34 Sim (Scratch in Miscarriage) Study Active, not recruiting NCT02681627 Not Applicable
35 Use of ROTEM Intraoperatively in Women With Placenta Accreta Enrolling by invitation NCT02729974 Not Applicable
36 Diagnostic Accuracy of Doppler Ultrasound and Role of Uterine Artery Doppler Not yet recruiting NCT03530475 Not Applicable
37 Multidisciplinary Team in Management of Placenta Accreta Not yet recruiting NCT03372538
38 Ultrasound in Prediction of Operative Findings in Cesarean Section Among Placenta Accreta Cases Not yet recruiting NCT03286998
39 PDIUC Protocol for Placental Accreta Not yet recruiting NCT03273569 Not Applicable
40 Bilateral Internal Iliac Artery Ligation Before Cesarean Hysterectomy Not yet recruiting NCT03129035 Not Applicable
41 ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility Not yet recruiting NCT03298633 Not Applicable
42 Delivery Timing in Morbidly Adherent Placentas: a Randomized, Controlled Trial Withdrawn NCT02635412 Not Applicable

Search NIH Clinical Center for Placenta Accreta

Cochrane evidence based reviews: placenta accreta

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Genetic Tests for Placenta Accreta

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Anatomical Context for Placenta Accreta

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MalaCards organs/tissues related to Placenta Accreta:

41
Placenta, Uterus, Ovary, Whole Blood, Endothelial, Cervix, Heart
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Publications for Placenta Accreta

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Articles related to Placenta Accreta:

(show top 50) (show all 551)
# Title Authors Year
1
The occurrence and severity of intra-abdominal adhesions in cases of pregnancies complicated by placenta accreta: A case control study. ( 29902712 )
2018
2
Intentional placental removal on suspicious placenta accreta spectrum: still prohibited? ( 29151230 )
2018
3
Placenta Accreta following Hysteroscopic Lysis of Adhesions Caused by Asherman's Syndrome: A Case Report and Literature Review. ( 29955406 )
2018
4
FIGO consensus guidelines on placenta accreta spectrum disorders: Conservative management. ( 29405320 )
2018
5
Subinvolution of the placental site associated with focal retained products of conception and placenta accreta mimicking uterine arteriovenous malformation on CT and MRI: a lesson to be learned. ( 29743751 )
2018
6
Impact of Targeted Scanning Protocols on Perinatal Outcomes in Pregnancies at Risk of Placenta Accreta Spectrum or Vasa Previa. ( 29353034 )
2018
7
Magnetic resonance imaging for diagnosis of placenta accreta spectrum disorders: still useful forA real-world practice. ( 29752929 )
2018
8
FIGO consensus guidelines on placenta accreta spectrum disorders: Prenatal diagnosis and screening. ( 29405319 )
2018
9
Bakri balloon for placenta accreta spectrum disorder: an alternative to caesarean hysterectomy? ( 29893151 )
2018
10
Placenta percreta is associated with more frequent severe maternal morbidity than placenta accreta. ( 29733839 )
2018
11
Prophylactic balloon occlusion of internal iliac arteries, common iliac arteries and infrarenal abdominal aorta in pregnancies complicated by placenta accreta: a retrospective cohort study. ( 29872910 )
2018
12
FIGO consensus guidelines on placenta accreta spectrum disorders: Epidemiology. ( 29405321 )
2018
13
FIGO consensus guidelines on placenta accreta spectrum disorders: Introduction. ( 29405322 )
2018
14
Placenta accreta spectrum disorders: A new standardized terminology better defining the condition. ( 29673011 )
2018
15
Matsubara-Takahashi cervix-holding technique for massive postpartum hemorrhage in patients with placenta previa with or without placenta accreta spectrum disorders. ( 29143329 )
2018
16
Concurrent intraoperative uterine rupture and placenta accreta. Do preoperative chronic hypertension, preterm premature rupture of membranes, chorioamnionitis, and placental abruption provide warning to this rare occurrence? ( 29756067 )
2018
17
International survey of practices used in the diagnosis and management of placenta accreta spectrum disorders. ( 29149470 )
2018
18
The risk of placenta accreta following primary cesarean delivery. ( 29404741 )
2018
19
Reply to "Retained placenta accreta with marked vascularity, uterine artery pseudoaneurysm, and placental polyp: overlapping clinical entities?" ( 29143937 )
2018
20
Temporary intra-arterial balloon occlusion for placenta accreta spectrum disorders: always inflate? ( 29934656 )
2018
21
FIGO consensus guidelines on placenta accreta spectrum disorders: Nonconservative surgical management. ( 29405317 )
2018
22
Clinical application of stage operation in patients with placenta accreta after previous caesarean section. ( 29851793 )
2018
23
Prior cesarean section and placenta accreta spectrum disorders: some clarifications. ( 29916109 )
2018
24
Placenta accreta and balloon catheterization: the experience of a single center and an update of latest evidence of literature. ( 29777345 )
2018
25
Placenta Accreta Spectrum. ( 29669225 )
2018
26
Intra-abdominal Rupture of a Live Cervical Pregnancy with Placenta Accreta but Without Vaginal Bleeding. ( 29849260 )
2018
27
Prior cesarean section and placenta accreta spectrum disorders: some clarifications. ( 29923020 )
2018
28
Imaging findings of concealed intra-amniotic hemorrhage in the setting of placenta previa and placenta accreta spectrum disorder. ( 29911274 )
2018
29
Case of heterotopic cervical pregnancy and total placenta accreta after artificial cycle frozen-thawed embryo transfer. ( 29371827 )
2018
30
Placenta accreta spectrum disorders: Prenatal diagnosis still lacks clinical correlation. ( 29924394 )
2018
31
Retained placenta accreta with marked vascularity, uterine artery pseudoaneurysm, and placental polyp: overlapping clinical entities? ( 29143936 )
2018
32
Placenta accreta spectrum disorder trends in the context of the universal two-child policy in China and the risk of hysterectomy. ( 29214633 )
2018
33
The new world of placenta accreta spectrum disorders. ( 29405318 )
2018
34
Intermittent aortic balloon occlusion combined with cesarean section for the treatment of patients with placenta previa complicated by placenta accreta: A retrospective study. ( 29974568 )
2018
35
Comparison of maternal and neonatal outcomes for patients with placenta accreta spectrum between online-to-offline management model with standard care model. ( 29408749 )
2018
36
Anesthetic management of cesarean section in cases of placenta accreta, with versus without abdominal aortic balloon occlusion: study protocol for a randomized controlled trial. ( 28549439 )
2017
37
Intraoperative aortic balloon occlusion in patients with placenta previa and/or placenta accreta: a retrospective study. ( 28420498 )
2017
38
Dynamic contrast enhanced MRI of the placenta: A tool for prenatal diagnosis of placenta accreta? ( 28487019 )
2017
39
Sclerotherapy for placenta accreta: Some concerns. ( 28420525 )
2017
40
Comparison of results of Bakri balloon tamponade and caesarean hysterectomy in management of placenta accreta and increta: a retrospective study. ( 28903630 )
2017
41
Balloon occlusion of internal iliac arteries in placenta accreta! ( 28442974 )
2017
42
Cervical Length in Patients at Risk for Placenta Accreta. ( 28339114 )
2017
43
Cervical varicosities may predict placenta accreta in posterior placenta previa: a magnetic resonance imaging study. ( 28710549 )
2017
44
A new approach to fertility-preserving surgery in patients with placenta accreta. ( 29157035 )
2017
45
Pathologically Diagnosed Placenta Accreta and Hemorrhagic Morbidity in a Subsequent Pregnancy. ( 28079779 )
2017
46
High-intensity focused ultrasound combined with hysteroscopic resection for the treatment of placenta accreta. ( 28856861 )
2017
47
Invasive placenta previa: Placental bulge with distorted uterine outline and uterine serosal hypervascularity at 1.5T MRI - useful features for differentiating placenta percreta from placenta accreta. ( 28770405 )
2017
48
The depletion of MARVELD1 leads to murine placenta accreta via integrin I^4-dependent trophoblast cell invasion. ( 28708243 )
2017
49
Discussion on the Timing of Balloon Occlusion of the Abdominal Aorta during a Caesarean Section in Patients with Pernicious Placenta Previa Complicated with Placenta Accreta. ( 29230417 )
2017
50
Disseminated intravascular coagulation syndrome two months after conservative management of placenta accreta. About two patients. ( 28689576 )
2017
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Variations for Placenta Accreta

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Expression for Placenta Accreta

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Search GEO for disease gene expression data for Placenta Accreta.
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Pathways for Placenta Accreta

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Pathways related to Placenta Accreta according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
ERK Signaling 64
Show member pathways
 13.54 ANGPT1 ANGPT2 FLT1 PGF TEK TNFRSF10B
2
TGF-Beta Pathway 64
Show member pathways
 13.22 ANGPT1 ANGPT2 FLT1 PGF TEK TNFRSF10B
3
Akt Signaling 64
Show member pathways
 13.12 ANGPT1 ANGPT2 FLT1 PGF TEK TNFRSF10B
4
Response to elevated platelet cytosolic Ca2+ 66
Show member pathways
 13.01 ANGPT1 ANGPT2 SERPINB2 SERPINE1 TEK TNFRSF10B
5
PAK Pathway 64
Show member pathways
 12.97 ANGPT1 ANGPT2 FLT1 PGF TEK TNFRSF10B
6
PI3K-Akt signaling pathway 37
Show member pathways
 12.7 ANGPT1 ANGPT2 FLT1 PGF TEK
7
MAPK signaling pathway 1 37
12.39 ANGPT1 ANGPT2 FLT1 PGF TEK
8
Immune response IL-23 signaling pathway 22
Show member pathways
 12.31 ANGPT1 ANGPT2 TEK
9
Ras signaling pathway 37
Show member pathways
 12.3 ANGPT1 ANGPT2 FLT1 PGF TEK
10
Cell surface interactions at the vascular wall 66
Show member pathways
 11.96 ANGPT1 ANGPT2 TEK TNFRSF10B
11
Tyrosine Kinases / Adaptors 4
11.91 ANGPT2 FLT1 TEK
12
Rheumatoid arthritis 37
11.67 ANGPT1 FLT1 TEK
13
Angiogenesis (CST) 4
11.65 ANGPT2 FLT1 TEK
14
Immune response IFN gamma signaling pathway 22
Show member pathways
 11.57 ANGPT1 ANGPT2 FLT1 PGF TNFRSF10B
15
G-protein signaling_H-RAS regulation pathway 22
11.16 ANGPT1 TEK
16
HIF-2-alpha transcription factor network 1
11.12 FLT1 SERPINE1
17
Photodynamic therapy-induced HIF-1 survival signaling 1
11.11 ANGPT1 ANGPT2 SERPINE1
18
HIF-1 signaling pathway 37
11.02 ANGPT1 ANGPT2 FLT1 SERPINE1 TEK
19
Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 1
10.97 ANGPT2 SERPINE1
20
VEGF ligand-receptor interactions 66
Show member pathways
 10.76 FLT1 PGF
21
Dissolution of Fibrin Clot 66
10.66 SERPINB2 SERPINE1
22
Angiogenesis (WikiPathways) 1
10.51 ANGPT1 FLT1 TEK
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GO Terms for Placenta Accreta

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Cellular components related to Placenta Accreta according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ANGPT1 ANGPT2 CGB3 FLT1 PGF SERPINB2
2 extracellular region GO:0005576 9.23 ANGPT1 ANGPT2 CGB3 FLT1 PGF SERPINB2
3 microvillus GO:0005902 9.16 ANGPT1 TEK

Biological processes related to Placenta Accreta according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.91 ANGPT1 ANGPT2 FLT1 PGF TEK TNFRSF10B
2 cell differentiation GO:0030154 9.88 ANGPT1 ANGPT2 FLT1 PGF TEK
3 negative regulation of apoptotic process GO:0043066 9.85 ANGPT1 FLT1 SERPINB2 TEK
4 cell-cell signaling GO:0007267 9.78 CGB3 PGF TEK
5 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.76 ANGPT1 FLT1 TEK
6 positive regulation of angiogenesis GO:0045766 9.72 ANGPT2 FLT1 PGF SERPINE1 TEK
7 leukocyte migration GO:0050900 9.71 ANGPT1 ANGPT2 TEK TNFRSF10B
8 response to hypoxia GO:0001666 9.7 ANGPT2 PGF TEK
9 positive regulation of MAPK cascade GO:0043410 9.69 FLT1 TEK TNFRSF10B
10 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.67 ANGPT1 FLT1 TEK
11 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.63 ANGPT1 FLT1 TEK
12 positive regulation of endothelial cell migration GO:0010595 9.6 ANGPT1 TEK
13 animal organ regeneration GO:0031100 9.59 ANGPT2 PGF
14 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 9.58 SERPINE1 TNFRSF10B
15 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.57 FLT1 TEK
16 blood vessel morphogenesis GO:0048514 9.56 ANGPT2 FLT1
17 fibrinolysis GO:0042730 9.54 SERPINB2 SERPINE1
18 negative regulation of endothelial cell apoptotic process GO:2000352 9.54 ANGPT1 SERPINE1 TEK
19 sprouting angiogenesis GO:0002040 9.46 ANGPT1 FLT1 PGF TEK
20 glomerulus vasculature development GO:0072012 9.43 ANGPT1 ANGPT2 TEK
21 Tie signaling pathway GO:0048014 9.13 ANGPT1 ANGPT2 TEK
22 angiogenesis GO:0001525 9.1 ANGPT1 ANGPT2 FLT1 PGF SERPINE1 TEK

Molecular functions related to Placenta Accreta according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.16 FLT1 TEK
2 receptor tyrosine kinase binding GO:0030971 8.96 ANGPT1 ANGPT2
3 growth factor binding GO:0019838 8.62 FLT1 TEK
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Sources for Placenta Accreta

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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