MCID: PLS005
MIFTS: 28

Plasmodium Ovale Malaria

Categories: Infectious diseases

Aliases & Classifications for Plasmodium Ovale Malaria

MalaCards integrated aliases for Plasmodium Ovale Malaria:

Name: Plasmodium Ovale Malaria 12 15 32
Ovale Malaria 12 71
Malariaby Plasmodium Ovale 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12919
ICD9CM 34 084.3
SNOMED-CT 67 19341001
ICD10 32 B53.0
UMLS 71 C0152072

Summaries for Plasmodium Ovale Malaria

Disease Ontology : 12 A malaria characaterized as a relatively mild form caused by a parasite Plasmodium ovale, which is characterized by tertian chills and febrile paroxysms, and that ends spontaneously.

MalaCards based summary : Plasmodium Ovale Malaria, also known as ovale malaria, is related to plasmodium vivax malaria and glucosephosphate dehydrogenase deficiency. An important gene associated with Plasmodium Ovale Malaria is G6PD (Glucose-6-Phosphate Dehydrogenase). The drugs chloroquine and Primaquine have been mentioned in the context of this disorder. Affiliated tissues include testes, spleen and liver.

Related Diseases for Plasmodium Ovale Malaria

Graphical network of the top 20 diseases related to Plasmodium Ovale Malaria:



Diseases related to Plasmodium Ovale Malaria

Symptoms & Phenotypes for Plasmodium Ovale Malaria

Drugs & Therapeutics for Plasmodium Ovale Malaria

Drugs for Plasmodium Ovale Malaria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
chloroquine Approved, Investigational, Vet_approved Phase 1 54-05-7 2719
2
Primaquine Approved Phase 1 90-34-6 4908
3 Analgesics Phase 1
4 Anti-Inflammatory Agents Phase 1
5 Anti-Infective Agents Phase 1
6 Analgesics, Non-Narcotic Phase 1
7 Anti-Inflammatory Agents, Non-Steroidal Phase 1
8 Antiprotozoal Agents Phase 1
9 Chloroquine diphosphate Phase 1 50-63-5
10 Antiparasitic Agents Phase 1
11 Antimalarials Phase 1
12 Antirheumatic Agents Phase 1
13 Anthelmintics Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 1, Open-Label Study to Evaluate Potential Pharmacokinetic Interaction of Orally Administered Primaquine and Chloroquine in Healthy Thai Adult Subjects Completed NCT01218932 Phase 1 A;B

Search NIH Clinical Center for Plasmodium Ovale Malaria

Genetic Tests for Plasmodium Ovale Malaria

Anatomical Context for Plasmodium Ovale Malaria

MalaCards organs/tissues related to Plasmodium Ovale Malaria:

40
Testes, Spleen, Liver, Lung, Monocytes, Neutrophil

Publications for Plasmodium Ovale Malaria

Articles related to Plasmodium Ovale Malaria:

(show top 50) (show all 162)
# Title Authors PMID Year
1
Case Report: Two Cases of Recurring Ovale Malaria in Sarawak, Malaysia, after Successful Treatment of Imported Plasmodium falciparum Infection. 61
31595863 2019
2
Mosquito and human hepatocyte infections with Plasmodium ovale curtisi and Plasmodium ovale wallikeri. 61
31162595 2019
3
Diagnosis of malaria in a traveler 9 months after returning from West Africa by illumigene® LAMP assay: A case report. 61
31137943 2019
4
[Analysis of imported malaria cases in Leshan City from 2012 to 2018]. 61
31612684 2019
5
Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent. 61
30763775 2019
6
[Imported Plasmodium ovale malaria in Hefei City: a case report]. 61
31184067 2019
7
[Epidemiological analysis of malaria prevalence in Jiangsu Province in 2017]. 61
31184052 2019
8
Acute respiratory distress syndrome and Plasmodium ovale malaria. 61
29886120 2019
9
Characterization of Plasmodium ovale spp. imported from Africa to Henan Province, China. 61
30778106 2019
10
Plasmodium ovale Infection After One Year Mefloquine Prophylaxis in A Young Indonesian Soldier: A Case Report. 61
31073108 2019
11
Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis. 61
30587297 2019
12
[Epidemic situation of malaria in Qingdao City from 2012 to 2017]. 61
30891980 2019
13
[Plasmodium ovale malaria and molecular diagnosis: Could it be a relapse?] 61
30683044 2019
14
[Epidemic situation of imported malaria in Beijing City, 2017]. 61
30567039 2018
15
[Evaluation of malaria elimination surveillance in Liyang City from 2010 to 2016]. 61
30567032 2018
16
Severe Plasmodium ovale malaria complicated by acute respiratory distress syndrome in a young Caucasian man. 61
29609605 2018
17
Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria. 61
29677199 2018
18
Molecular evidence for relapse of an imported Plasmodium ovale wallikeri infection. 61
29426330 2018
19
[Plasmodium ovale wallikeri and Plasmodium ovale curtisi Malaria in Senegal in 2016]. 61
29127650 2017
20
Two sympatric types of Plasmodium ovale and discrimination by molecular methods. 61
28065415 2017
21
[Spontaneous spleen rupture with P. ovale malaria]. 61
28545674 2017
22
[Epidemiological analysis of malaria prevalence in Jiangsu Province in 2015]. 61
29508576 2017
23
[Role of primaquine in malaria control and elimination in French-speaking Africa]. 61
28417346 2017
24
[Epidemiological analysis and countermeasures discussion on imported malaria in Zhangjiagang City]. 61
29508597 2017
25
DAT-positive Plasmodium ovale malaria presenting in a child with sickle cell anemia. 61
28211104 2017
26
[Epidemic situation of imported malaria in Chengdu City from 2012 to 2016]. 61
29508592 2017
27
A systematic review of the clinical presentation, treatment and relapse characteristics of human Plasmodium ovale malaria. 61
28284211 2017
28
[Polymorphisms of tryptophan-rich antigen gene of Plasmodium ovale subspecies from imported malaria cases in Henan Province]. 61
30133225 2017
29
[Epidemiological characteristics of imported malaria in Sichuan Province in 2015]. 61
30134088 2017
30
[Epidemiological Analysis of Imported Malaria in Tai’an City] of Shandong Province During 2011-2015]. 61
30141600 2016
31
[Analysis of epidemiological characteristics of imported malaria cases in Chongqing Municipality in 2015]. 61
29469538 2016
32
[Exploration of Using One-step Reverse Transcription PCR in Detection of Four Species of Human Malaria Parasites]. 61
30141596 2016
33
[Epidemiological analysis of malaria prevalence in Nanjing City from 2010 to 2015]. 61
29469256 2016
34
[Analysis of epidemic situation of imported malaria in Donghai County from 2005 to 2015]. 61
29469277 2016
35
[Analysis of imported malaria epidemic situation and implication for prevention and control strategy in Guangxi Zhuang Autonomous Region in 2014]. 61
29469265 2016
36
[Analysis on Malaria Situation in Shaanxi Province during 2005-2014]. 61
30130036 2016
37
Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics. 61
27527624 2016
38
Persistent Parasitism: The Adaptive Biology of Malariae and Ovale Malaria. 61
27480365 2016
39
[Epidemiological analysis of imported malaria in Hailing District, Taizhou City from 2010 to 2015]. 61
29376297 2016
40
[Epidemiological analysis of malaria prevalence in Taixing City from 2005 to 2015]. 61
29469268 2016
41
[Epidemiological analysis of malaria prevalence in Sichuan Province, 2012-2014]. 61
29376280 2016
42
PFMDR1 POLYMORPHISMS INFLUENCE ON IN VITRO SENSITIVITY OF THAI PLASMODIUM FALCIPARUM ISOLATES TO PRIMAQUINE, SITAMAQUINE AND TAFENOQUINE. 61
27405118 2016
43
[Epidemiologic characteristics of Plasmodium ovale in China in 2011-2014]. 61
27029361 2016
44
Dengue infection as a potential trigger of an imported Plasmodium ovale malaria relapse or a long incubation period in a non-endemic malaria region. 61
26809125 2016
45
[Analysis of malaria epidemic situation in Changzhou City from 2010 to 2014]. 61
29376290 2016
46
[Investigation and analysis of overseas imported malaria prevalence in Henan Province from 2012 to 2014]. 61
29376291 2016
47
[ Epidemiological Analysis of Imported Malaria in Shijiazhuang City from 2010 ]. 61
30120917 2016
48
Case report: spontaneous rupture of spleen in patient with Plasmodium ovale malaria. 61
26542132 2016
49
[Epidemiological analysis of malaria prevalence in Jiangsu Province in 2014]. 61
27097475 2015
50
[Analysis of malaria situation and discussion of control strategies in Huai'an City, 2014]. 61
26930950 2015

Variations for Plasmodium Ovale Malaria

Expression for Plasmodium Ovale Malaria

Search GEO for disease gene expression data for Plasmodium Ovale Malaria.

Pathways for Plasmodium Ovale Malaria

GO Terms for Plasmodium Ovale Malaria

Biological processes related to Plasmodium Ovale Malaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.33 MT-CYB G6PD CYP2D6
2 response to organic cyclic compound GO:0014070 8.96 MT-CYB G6PD
3 response to ethanol GO:0045471 8.62 MT-CYB G6PD

Molecular functions related to Plasmodium Ovale Malaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 8.8 MT-CYB G6PD CYP2D6

Sources for Plasmodium Ovale Malaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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