MCID: PLS031
MIFTS: 25

Plastic Bronchitis

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Plastic Bronchitis

MalaCards integrated aliases for Plastic Bronchitis:

Name: Plastic Bronchitis 58
Pseudo-Membranous Bronchitis 58 70
Croupous Bronchitis 58 70
Fibrinous Bronchitis 58

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

UMLS via Orphanet 71 C0264342 C0920258
Orphanet 58 ORPHA439881
UMLS 70 C0264342 C0920258

Summaries for Plastic Bronchitis

MalaCards based summary : Plastic Bronchitis, also known as pseudo-membranous bronchitis, is related to bronchitis and respiratory failure, and has symptoms including dyspnea and labored breathing. An important gene associated with Plastic Bronchitis is ALB (Albumin). The drugs Clotrimazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include heart.

Wikipedia : 73 Plastic bronchitis (PB) is a disorder in which branching casts of the airways are expectorated. PB is... more...

Related Diseases for Plastic Bronchitis

Diseases related to Plastic Bronchitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 bronchitis 11.1
2 respiratory failure 10.6
3 single ventricular heart 10.5
4 protein-losing enteropathy 10.4
5 influenza 10.4
6 sickle cell disease 10.4
7 bronchiectasis 10.3
8 acute chest syndrome 10.3
9 hypoplastic left heart syndrome 10.3
10 lung disease 10.3
11 aspergillosis 10.2
12 asthma 10.1
13 nephrotic syndrome 10.1
14 allergic disease 10.1
15 pneumothorax 10.1
16 thalassemia 10.1
17 tricuspid atresia 10.1
18 beta-thalassemia 10.1
19 thalassemia minor 10.1
20 constrictive pericarditis 10.1
21 allergic bronchopulmonary aspergillosis 10.1
22 pericarditis 10.1
23 status asthmaticus 10.1
24 posttransplant acute limbic encephalitis 10.1
25 uremia 10.0
26 fibrosis of extraocular muscles, congenital, 1 9.9
27 kaposi sarcoma 9.9
28 noonan syndrome 1 9.9
29 tetralogy of fallot 9.9
30 digeorge syndrome 9.9
31 cystic fibrosis 9.9
32 pulmonary atresia with intact ventricular septum 9.9
33 dermatitis, atopic 9.9
34 alpha-thalassemia 9.9
35 allergic rhinitis 9.9
36 asthma-related traits 2 9.9
37 human immunodeficiency virus type 1 9.9
38 leptin deficiency or dysfunction 9.9
39 anaplastic large cell lymphoma 9.9
40 cardiac arrest 9.9
41 intermittent asthma 9.9
42 near-fatal asthma 9.9
43 silicosis 9.9
44 sarcoma 9.9
45 adult respiratory distress syndrome 9.9
46 heart disease 9.9
47 bronchial disease 9.9
48 viral hepatitis 9.9
49 toxic encephalopathy 9.9
50 spindle cell sarcoma 9.9

Graphical network of the top 20 diseases related to Plastic Bronchitis:



Diseases related to Plastic Bronchitis

Symptoms & Phenotypes for Plastic Bronchitis

UMLS symptoms related to Plastic Bronchitis:


dyspnea; labored breathing

Drugs & Therapeutics for Plastic Bronchitis

Drugs for Plastic Bronchitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
2
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
3
Sirolimus Approved, Investigational Phase 2 53123-88-9 6436030 5284616
4 Antibiotics, Antitubercular Phase 2
5 Immunosuppressive Agents Phase 2
6 Immunologic Factors Phase 2
7 Anti-Bacterial Agents Phase 2
8 Anti-Infective Agents Phase 2
9 Antifungal Agents Phase 2
10 Fibrinolytic Agents Phase 2
11 Plasminogen Phase 2
12 Tissue Plasminogen Activator Phase 2
13 neurokinin A
14
Substance P 33507-63-0 44359816
15 Vasoactive intestinal peptide 40077-57-4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Efficacy and Safety of Sirolimus for Plastic Bronchitis:a Pilot Study Recruiting NCT03942926 Phase 2 Sirolimus
2 Safety and Efficacy of Inhaled Tissue Plasminogen Activator (tPA) for the Acute Treatment of Pediatric Plastic Bronchitis Recruiting NCT02315898 Phase 2 Treatment-inhaled tPA
3 Application of 68Ga NEB PET Imaging in the Diagnosis and Evaluation of Lymphatic Disorders, Including Lymphedema, Lymphangioma, Lymphangioleiomyomatosis, Plastic Bronchitis, Lymphadenopathy Caused by Rheumatoid Arthritis, Etc. Recruiting NCT04273334 Phase 1 68Ga-NEB
4 An Investigation Into The Potential Roles Of Vasoactive Intestinal Peptide And Substance P In The Pathophysiology Of Plastic Bronchitis And Protein Losing Enteropathy In Children With Palliated Single Ventricle Physiology Completed NCT01563757
5 International Plastic Bronchitis Registry Terminated NCT01663948

Search NIH Clinical Center for Plastic Bronchitis

Genetic Tests for Plastic Bronchitis

Anatomical Context for Plastic Bronchitis

MalaCards organs/tissues related to Plastic Bronchitis:

40
Heart

Publications for Plastic Bronchitis

Articles related to Plastic Bronchitis:

(show top 50) (show all 332)
# Title Authors PMID Year
1
Association of Lymphatic Abnormalities with Early Complications after Fontan Operation. 61
33383591 2021
2
Impact of adiposity on clinical outcomes in people living with a Fontan circulation. 61
33387555 2021
3
Pseudomembranous Tracheobronchitis With Severe Tracheal Stenosis and Masked Bronchial Obstruction. 61
33353810 2021
4
Clinical Analysis of Primary Nephrotic Syndrome Complicated by Plastic Bronchitis in Children. 61
33684950 2021
5
Characteristics and Outcome of Severe Mycoplasma pneumoniae Pneumonia Admitted to PICU in Shanghai: A Retrospective Cohort Study. 61
33786442 2021
6
Plastic Bronchitis and Noonan Syndrome. 61
33663876 2021
7
Pulmonary Manifestations of Congenital Heart Disease in Children. 61
33228936 2021
8
Management of Plastic Bronchitis Using α-Chymotrypsin: A Novel Treatment Modality. 61
33791174 2021
9
Direct EBUS-guided transtracheal lymphosclerosis for plastic bronchitis after Fontan. 61
32990404 2021
10
Plastic bronchitis in a toddler with a history of prematurity. 61
33524232 2021
11
[News and memories. From Covid-19 vaccine to plastic bronchitis…]. 61
33584874 2021
12
Fontan-associated plastic bronchitis waitlist and heart transplant outcomes: A PHTS analysis. 61
33405353 2021
13
Perioperative and long-term management of Fontan patients. 61
33431102 2021
14
Clinical characteristics of refractory mycoplasma pneumoniae pneumonia in children treated with glucocorticoid pulse therapy. 61
33509121 2021
15
Pre-Fontan Cardiac Catheterization Data as a Predictor of Prolonged Hospital Stay and Post-Discharge Adverse Outcomes Following the Fontan Procedure: A Single-Center Study. 61
32734530 2020
16
Pulmonary Vasodilator Therapy in Children with Single Ventricle Physiology: Effects on Saturation and Pulmonary Arterial Pressure. 61
32734529 2020
17
Lymphatic Disorders and Management in Patients with Congenital Heart Disease. 61
33373590 2020
18
Plastic Bronchitis Associated with Influenza: An Adult Case. 61
33361673 2020
19
Case report: hepatobronchial lymphatic communications in single ventricle patients as a pathophysiological mechanism of plastic bronchitis: diagnosis and treatment. 61
33442644 2020
20
Efficacy of fiberoptic bronchoscopy and bronchoalveolar lavage in childhood-onset, complicated plastic bronchitis. 61
32770770 2020
21
Abnormal pulmonary lymphatic flow in patients with paediatric pulmonary lymphatic disorders: Diagnosis and treatment. 61
32792289 2020
22
Path ahead for 'low risk' adolescents living with a Fontan circulation. 61
33229361 2020
23
[Analysis of clinical characteristics and risk factors of influenza-related deaths in children]. 61
33120463 2020
24
Pediatric pulmonary lymphatic flow Disorders: Diagnosis and management. 61
31884062 2020
25
Diagnosis and Management of Lymphatic Disorders in Congenital Heart Disease. 61
33037935 2020
26
Use of institutional criteria for transcatheter device closure of Fontan fenestration - Midterm outcomes. 61
33311921 2020
27
Thoracic duct decompression and jugular vein banding-an effective treatment option for protein-losing enteropathy and plastic bronchitis in severe failing Fontan circulation: a case report. 61
33204944 2020
28
Plastic bronchitis associated with Botrytis cinerea infection in a child: A case report. 61
33195676 2020
29
[Clinical features of children with influenza and plastic bronchitis: an analysis of 63 cases]. 61
33059808 2020
30
Perioperative respiratory distress in a child due to plastic bronchitis triggered by allergic reaction to sevoflurane. 61
32948530 2020
31
Longitudinal changes in echocardiographic measures of ventricular function after Fontan operation. 61
32789899 2020
32
Imaging of complications following Fontan circulation in children - diagnosis and surveillance. 61
32468285 2020
33
Plastic Bronchitis: A Manifestation of Dander Hypersensitivity. 61
32844770 2020
34
Protein-losing enteropathy and plastic bronchitis after the Fontan procedure. 61
32928546 2020
35
Heterotaxy Is Not a Risk Factor for Adverse Long-Term Outcomes After Fontan Completion. 61
31891693 2020
36
Plastic Bronchitis. 61
32433279 2020
37
Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19. 61
32329246 2020
38
Magnetic Resonance Lymphangiography. 61
32471538 2020
39
Quantification of Thoracic Lymphatic Flow Patterns Using Dynamic Contrast-enhanced MR Lymphangiography. 61
32368962 2020
40
Plastic bronchitis associated with adenovirus serotype 7 in children. 61
32493254 2020
41
Human Deoxyribonuclease (rhDNase) Nebulization as an Alternative Treatment for Refractory Plastic Bronchitis After Fontan Surgery. 61
32405674 2020
42
Treatment and outcome of plastic bronchitis in single ventricle patients: a systematic review. 61
32451550 2020
43
Fontan-associated nephropathy: Predictors and outcomes. 61
31955974 2020
44
[Clinical features of severe type 7 adenovirus pneumonia: an analysis of 45 cases]. 61
32434636 2020
45
Prevalence and Cause of Early Fontan Complications: Does the Lymphatic Circulation Play a Role? 61
32223393 2020
46
Extracardiac Fontan Fenestration Device Closure with Amplatzer Vascular Plug II and Septal Occluder: Procedure Results and Medium-Term Follow-Up. 61
31894396 2020
47
High-flow nasal cannula for the treatment of life-threatening plastic bronchitis. 61
32068971 2020
48
Current evaluation and management of plastic bronchitis in the pediatric population. 61
31812839 2020
49
Balancing a single-ventricle circulation: 'physiology to therapy'. 61
33061117 2020
50
[Clinical features of influenza with plastic bronchitis in children]. 61
32051075 2020

Variations for Plastic Bronchitis

Expression for Plastic Bronchitis

Search GEO for disease gene expression data for Plastic Bronchitis.

Pathways for Plastic Bronchitis

GO Terms for Plastic Bronchitis

Sources for Plastic Bronchitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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