PMF
MCID: PLT031
MIFTS: 34

Platelet Membrane Fluidity (PMF)

Categories: Blood diseases

Aliases & Classifications for Platelet Membrane Fluidity

MalaCards integrated aliases for Platelet Membrane Fluidity:

Name: Platelet Membrane Fluidity 57 40
Pmf 57 3

Classifications:



External Ids:

OMIM 57 173560

Summaries for Platelet Membrane Fluidity

CDC : 3 Application period for the PMF Class of 2019 is now closed. Application period for the Class of 2020 will open in Fall 2019.

MalaCards based summary : Platelet Membrane Fluidity, also known as pmf, is related to hypertension, essential and ischemia. An important gene associated with Platelet Membrane Fluidity is NOS2 (Nitric Oxide Synthase 2), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Prolactin Signaling Pathway. Affiliated tissues include testes, lung and heart, and related phenotypes are liver/biliary system and renal/urinary system

Description from OMIM: 173560

Related Diseases for Platelet Membrane Fluidity

Graphical network of the top 20 diseases related to Platelet Membrane Fluidity:



Diseases related to Platelet Membrane Fluidity

Symptoms & Phenotypes for Platelet Membrane Fluidity

Clinical features from OMIM:

173560

MGI Mouse Phenotypes related to Platelet Membrane Fluidity:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.43 NOS2 NOS3 SELP
2 renal/urinary system MP:0005367 9.33 NOS2 NOS3 SELP
3 respiratory system MP:0005388 9.13 NOS2 NOS3 SELP
4 vision/eye MP:0005391 8.8 NOS2 NOS3 SELP

Drugs & Therapeutics for Platelet Membrane Fluidity

Search Clinical Trials , NIH Clinical Center for Platelet Membrane Fluidity

Genetic Tests for Platelet Membrane Fluidity

Anatomical Context for Platelet Membrane Fluidity

MalaCards organs/tissues related to Platelet Membrane Fluidity:

41
Testes, Lung, Heart, Colon, Kidney, Bone, Bone Marrow

Publications for Platelet Membrane Fluidity

Articles related to Platelet Membrane Fluidity:

(show top 50) (show all 139)
# Title Authors Year
1
Vehicular contribution of PAHs in size dependent road dust: A source apportionment by PCA-MLR, PMF, and Unmix receptor models. ( 30308902 )
2019
2
Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients. ( 28745329 )
2018
3
Source apportionment of heavy metals in agricultural soil based on PMF: A case study in Hexi Corridor, northwest China. ( 29131977 )
2018
4
Source Apportionment of Total Suspended Particles (TSP) by Positive Matrix Factorization (PMF) and Chemical Mass Balance (CMB) Modeling in Ahvaz, Iran. ( 29313074 )
2018
5
Source apportionment of ambient PM2.5 in two locations in central Tehran using the Positive Matrix Factorization (PMF) model. ( 29455128 )
2018
6
Source apportionment of PM2.5 using positive matrix factorization (PMF) at a rural site in Korea. ( 29533830 )
2018
7
A hybrid source apportionment strategy using positive matrix factorization (PMF) and molecular marker chemical mass balance (MM-CMB) models. ( 29533882 )
2018
8
Source and path identification of metals pollution in a mining area by PMF and rare earth element patterns in road dust. ( 29758917 )
2018
9
ASXL1/EZH2 mutations promote clonal expansion of neoplastic HSC and impair erythropoiesis in PMF. ( 29907810 )
2018
10
Synthesis of nanoporous poly-melamine-formaldehyde (PMF) based on Schiff base chemistry as a highly efficient adsorbent. ( 30398492 )
2018
11
Ambient air quality in the holy city of Makkah: A source apportionment with elemental enrichment factors (EFs) and factor analysis (PMF). ( 30408866 )
2018
12
Simultaneous measurement of displacement and temperature using a PMF-based dual Mach-Zehnder interferometer. ( 30461752 )
2018
13
Assessment of PM2.5 sources and their corresponding level of uncertainty in a coastal urban area using EPA PMF 5.0 enhanced diagnostics. ( 27631196 )
2017
14
Characterization and source apportionment of PM2.5 based on error estimation from EPA PMF 5.0 model at a medium city in China. ( 28088626 )
2017
15
Selected Bioinformatic Tools and MS (MALDI-TOF, PMF) Techniques Used in the Strategy for the Identification of Oat Proteins After 2-DE. ( 28132156 )
2017
16
Chemical characteristics and source apportionment of PM2.5 using PCA/APCS, UNMIX, and PMF at an urban site of Delhi, India. ( 28455568 )
2017
17
Pre-PMF emerging as important subgroup of MPN. ( 28620103 )
2017
18
Prefibrotic/early vs overt PMF. ( 28620109 )
2017
19
Poly-4-vinylphenol (PVP) and Poly(melamine-co-formaldehyde) (PMF)-Based Atomic Switching Device and Its Application to Logic Gate Circuits with Low Operating Voltage. ( 28777534 )
2017
20
Sediment PAH source apportionment in the Liaohe River using the ME2 approach: A comparison to the PMF model. ( 26925728 )
2016
21
An inter-comparison of PM10 source apportionment using PCA and PMF receptor models in three European sites. ( 27094272 )
2016
22
Application of PMF and CMB receptor models for the evaluation of the contribution of a large coal-fired power plant to PM10 concentrations. ( 27101448 )
2016
23
Study on the Application of the Combination of TMD Simulation and Umbrella Sampling in PMF Calculation for Molecular Conformational Transitions. ( 27171075 )
2016
24
Source Apportionment of PM2.5 in Delhi, India Using PMF Model. ( 27209541 )
2016
25
Water quality assessment and apportionment of pollution sources using APCS-MLR and PMF receptor modeling techniques in three major rivers of South Florida. ( 27317134 )
2016
26
Seasonality in size-segregated ionic composition of ambient particulate pollutants over the Indo-Gangetic Plain: Source apportionment using PMF. ( 27622841 )
2016
27
Source identification and apportionment of PM2.5 and PM2.5-10 in iron and steel scrap smelting factory environment using PMF, PCFA and UNMIX receptor models. ( 27645143 )
2016
28
The European Innovation Partnership on Active and Healthy Ageing Synergies: Protocol for a Prospective Observational Study to Measure the Impact of a Community-Based Program on Prevention and Mitigation of Frailty (ICP - PMF) in Community-Dwelling Older Adults. ( 27896228 )
2016
29
Megadosemethilprednisolone (mdmp) For Primary Myelofibrosis (pmf). ( 26377619 )
2015
30
Ground and excited electronic state analysis of PrF²⁺ and PmF²⁺. ( 25397590 )
2015
31
Combination of Unmix and PMF receptor model to apportion the potential sources and contributions of PAHs in wetland soils from Jiaozhou Bay, China. ( 25434785 )
2015
32
Local and regional components of aerosol in a heavily trafficked street canyon in central London derived from PMF and cluster analysis of single-particle ATOFMS spectra. ( 25695365 )
2015
33
Methods for estimating uncertainty in PMF solutions: examples with ambient air and water quality data and guidance on reporting PMF results. ( 25776202 )
2015
34
Accounting for Intraligand Interactions in Flexible Ligand Docking with a PMF-Based Scoring Function. ( 26418299 )
2015
35
Calreticulin mutated prefibrotic-stage myelofibrosis and PMF represent an independent clone from coexisting CLL. ( 25190754 )
2014
36
Source apportionment of the carcinogenic potential of polycyclic aromatic hydrocarbons (PAH) associated to airborne PM10 by a PMF model. ( 24022101 )
2014
37
Characterization of the Danube River sediments using the PMF multivariate approach. ( 24120015 )
2014
38
Liquid-liquid extraction of uranyl by TBP: the TBP and ions models and related interfacial features revisited by MD and PMF simulations. ( 24601645 )
2014
39
Source apportionment of atmospheric PM2.5-bound polycyclic aromatic hydrocarbons by a PMF receptor model. Assessment of potential risk for human health. ( 25240190 )
2014
40
A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF). ( 23330839 )
2013
41
Tracer-based source apportionment of polycyclic aromatic hydrocarbons in PM2.5 in Guangzhou, southern China, using positive matrix factorization (PMF). ( 22926284 )
2013
42
Drug permeability prediction using PMF method. ( 23104229 )
2013
43
Water PMF for predicting the properties of water molecules in protein binding site. ( 23114863 )
2013
44
Oil-soluble and water-soluble BTPhens and their europium complexes in octanol/water solutions: interface crossing studied by MD and PMF simulations. ( 23293892 )
2013
45
Liquid-liquid extraction of uranyl by an amide ligand: interfacial features studied by MD and PMF simulations. ( 23746355 )
2013
46
Tracking polychlorinated biphenyls (PCBs) congener patterns in Newark Bay surface sediment using principal component analysis (PCA) and positive matrix factorization (PMF). ( 23831929 )
2013
47
Assessment of the sources of suspended particulate matter aerosol using US EPA PMF 3.0. ( 21472386 )
2012
48
The application of Positive Matrix Factorization (PMF) to eco-efficiency analysis. ( 22325638 )
2012
49
The platysma myocutaneous flap (PMF) for head and neck reconstruction: a retrospective and multicentric analysis of 91 T1-T2 patients. ( 22444352 )
2012
50
iMOWSE, a scoring scheme bridging in silico and in vitro digestion in PMF. ( 22479821 )
2012

Variations for Platelet Membrane Fluidity

Expression for Platelet Membrane Fluidity

Search GEO for disease gene expression data for Platelet Membrane Fluidity.

Pathways for Platelet Membrane Fluidity

Pathways related to Platelet Membrane Fluidity according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.79 NOS2 NOS3 SELP
2
Show member pathways
12.04 NOS2 NOS3
3
Show member pathways
12.03 NOS2 NOS3
4
Show member pathways
11.96 NOS2 NOS3
5
Show member pathways
11.84 NOS2 NOS3
6
Show member pathways
11.83 NOS2 NOS3
7
Show member pathways
11.78 NOS2 NOS3
8 11.66 NOS2 NOS3
9 11.59 NOS2 SELP
10 11.49 NOS2 NOS3
11 11.3 NOS2 NOS3
12
Show member pathways
11.23 NOS2 NOS3
13
Show member pathways
11.19 NOS2 NOS3
14
Show member pathways
11.03 NOS2 NOS3
15
Show member pathways
10.97 NOS2 NOS3
16 10.77 NOS2 NOS3
17
Show member pathways
10.67 NOS2 NOS3
18 10.54 NOS2 NOS3
19 10.07 NOS2 NOS3
20 9.53 NOS2 NOS3

GO Terms for Platelet Membrane Fluidity

Cellular components related to Platelet Membrane Fluidity according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vesicle membrane GO:0012506 8.62 NOS2 NOS3

Biological processes related to Platelet Membrane Fluidity according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-negative bacterium GO:0050829 9.46 NOS2 SELP
2 cell redox homeostasis GO:0045454 9.43 NOS2 NOS3
3 response to hormone GO:0009725 9.4 NOS2 NOS3
4 negative regulation of blood pressure GO:0045776 9.37 NOS2 NOS3
5 nitric oxide mediated signal transduction GO:0007263 9.32 NOS2 NOS3
6 nitric oxide biosynthetic process GO:0006809 9.26 NOS2 NOS3
7 positive regulation of guanylate cyclase activity GO:0031284 9.16 NOS2 NOS3
8 response to lipopolysaccharide GO:0032496 9.13 NOS2 NOS3 SELP
9 arginine catabolic process GO:0006527 8.62 NOS2 NOS3

Molecular functions related to Platelet Membrane Fluidity according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calmodulin binding GO:0005516 9.46 NOS2 NOS3
2 heme binding GO:0020037 9.43 NOS2 NOS3
3 flavin adenine dinucleotide binding GO:0050660 9.4 NOS2 NOS3
4 NADP binding GO:0050661 9.37 NOS2 NOS3
5 FMN binding GO:0010181 9.32 NOS2 NOS3
6 arginine binding GO:0034618 9.26 NOS2 NOS3
7 NADPH-hemoprotein reductase activity GO:0003958 9.16 NOS2 NOS3
8 tetrahydrobiopterin binding GO:0034617 8.96 NOS2 NOS3
9 nitric-oxide synthase activity GO:0004517 8.62 NOS2 NOS3

Sources for Platelet Membrane Fluidity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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