MCID: PLM005
MIFTS: 33

Pleomorphic Lipoma

Categories: Cancer diseases

Aliases & Classifications for Pleomorphic Lipoma

MalaCards integrated aliases for Pleomorphic Lipoma:

Name: Pleomorphic Lipoma 12 15 73
Lipoma 44 73
Lipomatosis, Multiple 73
Lipoma Pleomorphic 55

Classifications:



External Ids:

Disease Ontology 12 DOID:10192
MeSH 44 D008067
NCIt 50 C3703
SNOMED-CT 68 21396005

Summaries for Pleomorphic Lipoma

Disease Ontology : 12 A lipoma that is characterized by floret giant cells with overlapping nuclei.

MalaCards based summary : Pleomorphic Lipoma, also known as lipoma, is related to infiltrating lipoma and well-differentiated liposarcoma. An important gene associated with Pleomorphic Lipoma is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Signaling by ERBB4. The drug Afinitor has been mentioned in the context of this disorder. Affiliated tissues include colon, tongue and spinal cord.

Wikipedia : 76 Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of... more...

Related Diseases for Pleomorphic Lipoma

Diseases related to Pleomorphic Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 363)
# Related Disease Score Top Affiliating Genes
1 infiltrating lipoma 33.2 HMGA2 MDM2
2 well-differentiated liposarcoma 32.3 HMGA2 MDM2
3 liposarcoma 30.3 HMGA2 MDM2
4 atypical lipomatous tumor 30.1 HMGA2 MDM2
5 lipomatosis, multiple 29.8 HMGA2 MDM2
6 leiomyoma 29.8 HMGA2 PGR
7 myoma 29.7 HMGA2 PGR
8 dedifferentiated liposarcoma 29.7 HMGA2 MDM2
9 myxoid liposarcoma 29.7 HMGA2 MDM2
10 pleomorphic adenoma 29.7 HMGA2 MDM2
11 leiomyoma, uterine 29.6 HMGA2 PGR
12 leiomyosarcoma 29.2 MDM2 PGR
13 nasopalpebral lipoma-coloboma syndrome 12.4
14 skin lipoma 12.4
15 chondroid lipoma 12.4
16 chest wall lipoma 12.3
17 pleural lipoma 12.3
18 spinal cord lipoma 12.3
19 lipoma of spermatic cord 12.3
20 tendon sheath lipoma 12.3
21 thymus lipoma 12.3
22 large intestine lipoma 12.2
23 gallbladder lipoma 12.2
24 extrahepatic bile duct lipoma 12.2
25 central nervous system lipoma 12.2
26 epicardium lipoma 12.2
27 lipoma of colon 12.2
28 corpus callosum lipoma 12.2
29 endobronchial lipoma 12.1
30 breast lipoma 12.1
31 axillary lipoma 12.1
32 lumbosacral lipoma 12.1
33 esophageal lipoma 12.1
34 liver lipoma 12.1
35 internal auditory canal lipoma 12.1
36 lipoma of the rectum 12.1
37 classic type lipoma 12.1
38 paratesticular lipoma 12.1
39 cleft, median, of upper lip with polyps of facial skin and nasal mucosa 12.1
40 lipoma of the conjunctiva 12.0
41 kidney lipoma 12.0
42 external auditory meatus lipoma 12.0
43 cerebral hemisphere lipoma 12.0
44 cowden syndrome 1 11.9
45 heart lipoma 11.9
46 cleft lip/palate-deafness-sacral lipoma syndrome 11.9
47 lipomatosis, multiple symmetric 11.6
48 lipomatosis 11.6
49 encephalocraniocutaneous lipomatosis 11.5
50 angiolipoma 11.5

Graphical network of the top 20 diseases related to Pleomorphic Lipoma:



Diseases related to Pleomorphic Lipoma

Symptoms & Phenotypes for Pleomorphic Lipoma

Drugs & Therapeutics for Pleomorphic Lipoma

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Afinitor 18 49 EVEROLIMUS Novartis March 2009

Search Clinical Trials , NIH Clinical Center for Pleomorphic Lipoma

Cochrane evidence based reviews: lipoma

Genetic Tests for Pleomorphic Lipoma

Anatomical Context for Pleomorphic Lipoma

MalaCards organs/tissues related to Pleomorphic Lipoma:

41
Colon, Tongue, Spinal Cord, Liver, Lung, Skin, B Cells

Publications for Pleomorphic Lipoma

Articles related to Pleomorphic Lipoma:

(show top 50) (show all 621)
# Title Authors Year
1
Atypical multivacuolated lipoblasts and atypical mitoses are not compatible with the diagnosis of spindle cell/pleomorphic lipoma. ( 29317234 )
2018
2
Atypical multivacuolated lipoblasts and atypical mitoses are not compatible with the diagnosis of spindle cell/pleomorphic lipoma-reply. ( 29320749 )
2018
3
Pleomorphic lipoma. ( 29328546 )
2018
4
Spindle cell lipoma mimicking pleomorphic adenoma: A diagnostic challenge on cytology. ( 30468314 )
2018
5
Tubular adenoma overlying a colonic lipoma resected by endoscopic mucosal resection using detachable endoloop. ( 30503845 )
2018
6
Lipoma of the transverse colon covered by tubulovillous adenoma: a rare indication for surgical treatment. ( 29549684 )
2018
7
Intussusception secondary to descending colon lipoma presenting with simultaneous acute appendicitis. ( 29992005 )
2018
8
Coincidence of Tethered Cord, Filum Terminale Lipoma, and Sacral Dural Arteriovenous Fistula: Report of Two Cases and a Literature Review. ( 30319536 )
2018
9
Carpal Tunnel Syndrome Caused by Intraneural Lipoma of the Median Nerve and Arteriovenous Malformation. ( 29731590 )
2018
10
Capillary hemangioma involved in filar lipoma: A case report. ( 30309451 )
2018
11
Obesity and pericallosal lipoma in X-linked emery-dreifuss muscular dystrophy: A case report - Does Emerin play a role in adipocyte differentiation? ( 30079154 )
2018
12
Endobronchial lipoma with tuberculosis: A solitary coetaneousness. ( 29319046 )
2018
13
Pericallosal Lipoma and Cortical Dysplasia Masquerading as a Glioma. ( 30083489 )
2018
14
Complete small bowel obstruction without intussusception due to a submucosal lipoma. ( 29992008 )
2018
15
Colonic intussusception caused by a sigmoidal lipoma: A case report. ( 30059860 )
2018
16
Pedunculated small bowel lipoma with heterotopic pancreas causing intussusception. ( 30214784 )
2018
17
Laparoscopic segmental resection of the rectum for upper rectal intussusception caused by a giant rectal lipoma: A case report. ( 30278497 )
2018
18
Intussusception of colonic lipoma with ischaemic necrosis: a new colonoscopic finding. ( 30294849 )
2018
19
Ileoileal and ileocecal intussusception due to ileal lipoma: A rare cause of bowel obstruction in the adult. ( 28684032 )
2018
20
An intraspinal extradural lipoma with spinal epidural lipomatosis: A case report and a review of literature. ( 30488010 )
2018
21
Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature. ( 29541595 )
2018
22
Liposarcoma Preoperatively Diagnosed as Lipoma: 10-Year Experience at a Single Institution. ( 29659409 )
2018
23
Successful removal of giant mediastinal lipoma and liposarcoma involving both chest cavities: Two case reports. ( 30095647 )
2018
24
Fatty tumors of the retroperitoneum: Lipoma or well-differentiated liposarcoma. About a case of a giant retroperitoneal liposarcoma. ( 30211007 )
2018
25
Multiple well-differentiated cardiac liposarcoma with a concomitant myocardial lipoma: A case report. ( 30546890 )
2018
26
Immunohistochemical differentiation between spindle cell lipoma and neurofibroma of oral cavity using CD34 and SOX10. ( 30303149 )
2018
27
Simultaneous Median and Ulnar Compression Neuropathy Secondary to a Giant Palmar Lipoma: A Case Report and Review of the Literature. ( 29666776 )
2018
28
Pleural lipoma presenting with back pain. ( 27323307 )
2018
29
Transient Anarthria and Quadriplegia in a Patient with Basilar Artery Hypoplasia and Coincidental Intracranial Lipoma: A Case Report. ( 30519181 )
2018
30
Dysplastic Lipoma: A Distinctive Atypical Lipomatous Neoplasm With Anisocytosis, Focal Nuclear Atypia, p53 Overexpression, and a Lack of MDM2 Gene Amplification by FISH; A Report of 66 Cases Demonstrating Occasional Multifocality and a Rare Association With Retinoblastoma. ( 30001242 )
2018
31
Giant bipolar intramedullary nondysraphic spinal cord lipoma: A case report. ( 30396693 )
2018
32
Intramedullary Spinal Cord Lipoma Mimicking a Late Subacute Hematoma. ( 30459918 )
2018
33
Low-fat, plexiform spindle cell lipoma of the lip expressing S100 protein: a neural tumor simulator. ( 29940654 )
2018
34
Pericallosal lipoma masquerading as venous thrombosis on magnetic resonance imaging. ( 30504604 )
2018
35
Gastrointestinal: Gastric lipoma as a rare cause of recurrent gastrointestinal bleeding. ( 29542245 )
2018
36
Giant pericallosal lipoma presenting with psychosis. ( 29547194 )
2018
37
Cardiac Lipoma: An Uncharacteristically Large Intra-Atrial Mass Causing Symptoms. ( 29552360 )
2018
38
Medical image analysis of knee joint lipoma arborescens and arthroscopic treatment. ( 29567561 )
2018
39
Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells. ( 29568880 )
2018
40
A case of junctional neural tube defect associated with a lipoma of the filum terminale: a new subtype of junctional neural tube defect? ( 29600904 )
2018
41
Preoperative radiologic patent blue localization for intracorporeal laparoscopic resection of a terminal ileal submucosal lipoma: A case report. ( 29604532 )
2018
42
Accessory scrotum and congenital perineal lipoma in a child with type 2 congenital pulmonary airway malformation: A report of an unusual. ( 29623024 )
2018
43
Frontal subcutaneous lipoma associated with interhemispheric lipoma, lipomeningocele, and corpus callosal dysgenesis in a young adult: CT and MRI findings. ( 29692522 )
2018
44
An Incidental Periscapular Lipoma With Marked Bone Erosion in an Elderly Woman With Contralateral Shoulder Pain. ( 29705170 )
2018
45
Para-anal lipoma as a rare consequence to perineal trauma. Case-report and review of the literature. ( 29734868 )
2018
46
A Large Size Lipoma at Spinoglenoid Notch Mimicked Traumatic Rotator Cuff Tear. ( 29734906 )
2018
47
A case report of multi-compartmental lipoma of the hand. ( 29736408 )
2018
48
Thoracoscopic resection of parosteal lipoma of the rib using orthopedic electric micro drill. ( 29744749 )
2018
49
Noninvasive size reduction of lipoma with an insulated monopolar radiofrequency microneedle device. ( 29744986 )
2018
50
Retropharyngeal lipoma presenting with snoring in a child. ( 29752203 )
2018

Variations for Pleomorphic Lipoma

Expression for Pleomorphic Lipoma

Search GEO for disease gene expression data for Pleomorphic Lipoma.

Pathways for Pleomorphic Lipoma

Pathways related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.23 HMGA2 MDM2
2
Show member pathways
10.66 MDM2 PGR

GO Terms for Pleomorphic Lipoma

Sources for Pleomorphic Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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