Pleural Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PLR006 MIFTS: 37	Pleural Cancer Categories: Cancer diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Pleural Cancer

MalaCards integrated aliases for Pleural Cancer:

Name: Pleural Cancer ¹² ¹⁵

Pleural Neoplasms ⁴⁴ ⁷¹

Malignant Tumor of Pleura ⁷¹

Neoplasm of Pleura ¹²

Pleural Tumor ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Neoplasms

Malignant neoplasms of respiratory and intrathoracic organs

Malignant neoplasm of heart, mediastinum and pleura

Malignant neoplasm: Pleura

External Ids:

Disease Ontology ¹² DOID:5158

ICD9CM ³⁴ 163

MeSH ⁴⁴ D010997

NCIt ⁵⁰ C3332 C3547

SNOMED-CT ⁶⁷ 126719004 363433009

ICD10 ³² C38.4

UMLS ⁷¹ C0032229 C0153494

Sources

Summaries for Pleural Cancer

Disease Ontology : ¹² A connective tissue cancer that located in the pleura.

MalaCards based summary : Pleural Cancer, also known as pleural neoplasms, is related to malignant pleural mesothelioma and benign mesothelioma. An important gene associated with Pleural Cancer is MUC16 (Mucin 16, Cell Surface Associated), and among its related pathways/superpathways is MicroRNAs in cancer. The drugs Pemetrexed and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include pleura, heart and lung.

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Related Diseases for Pleural Cancer

Diseases related to Pleural Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)

#	Related Disease	Score	Top Affiliating Genes
1	malignant pleural mesothelioma	31.4	NF2 MSLN MIR625 MIR411 MIR223 MIR193A
2	benign mesothelioma	30.9	NF2 MSLN CALB2
3	lung cancer susceptibility 3	29.9	MUC16 MSLN MIR17 H2AC18 CALB2
4	mesothelioma, malignant	29.6	NF2 MUC16 MSLN MIR625 MIR32 MIR29C
5	pleural disease	28.8	NF2 MSLN MIRLET7A1 MIR625 MIR411 MIR32
6	malignant pleural solitary fibrous tumor	11.0
7	pseudo-meigs syndrome	10.5	MUC16 CALB2
8	liver fibroma	10.4	MSLN CALB2
9	pericardium cancer	10.4	MSLN CALB2
10	cystadenofibroma	10.4	MUC16 CALB2
11	adenofibroma	10.4	MUC16 CALB2
12	purulent labyrinthitis	10.4	NF2 MIRLET7A1
13	malignant biphasic mesothelioma	10.4	MSLN CALB2
14	ovarian cystadenocarcinoma	10.4	MUC16 MIR17 CALB2
15	malignant peritoneal mesothelioma	10.4	NF2 BAP1
16	ovary adenocarcinoma	10.4	MUC16 MIR17 H2AC18
17	pericardial mesothelioma	10.4	MUC16 MIR32 MIR17 CALB2
18	leiomyoma, uterine	10.4	MIR32 MIR29C MIR139
19	bladder carcinoma in situ	10.3	MIR142 MIR139
20	angiomatous meningioma	10.3	NF2 BAP1
21	extrinsic cardiomyopathy	10.3	MIR223 MIR142 H2AC18
22	sarcomatoid mesothelioma	10.3	MSLN CALB2 BAP1
23	infratentorial cancer	10.3	MIR17 MIR142 H2AC18
24	mucinous stomach adenocarcinoma	10.3	NF2 CALB2
25	autoimmune disease of gastrointestinal tract	10.3	MIR223 MIR142 H2AC18
26	fallopian tube endometrioid adenocarcinoma	10.3	MUC16 CALB2
27	bronchial disease	10.3	MIR17 MIR142 H2AC18
28	bone resorption disease	10.3	MIR93 MIR142 H2AC18
29	spinal cord disease	10.3	NF2 MIR142 H2AC18
30	bone remodeling disease	10.3	MIR93 MIR142 H2AC18
31	atypical teratoid rhabdoid tumor	10.3	NF2 MIR193A MIR142
32	retinal cancer	10.3	MIR193A MIR17 MIR142 H2AC18
33	meningioma, radiation-induced	10.3	NF2 BAP1
34	ocular cancer	10.3	MIR193A MIR17 MIR142 H2AC18
35	thyroid gland disease	10.3	MIR17 MIR142 MIR138-1 H2AC18
36	uveal disease	10.3	MIR142 H2AC18 BAP1
37	autonomic nervous system neoplasm	10.3	MIR193A MIR17 MIR142 H2AC18
38	autoimmune disease of musculoskeletal system	10.3	MIR223 MIR17 MIR142 H2AC18
39	bone inflammation disease	10.3	MIR223 MIR17 MIR142 H2AC18
40	sezary's disease	10.3	MIRLET7A1 MIR223 MIR17
41	leukocyte disease	10.3	MIR17 MIR142 H2AC18
42	bile duct adenocarcinoma	10.3	MIR30E MIR17 MIR142 H2AC18
43	mouth disease	10.3	MIR193A MIR17 MIR142 H2AC18
44	bone marrow cancer	10.3	MIR30E MIR17 MIR142 H2AC18
45	primary bacterial infectious disease	10.3	MIR93 MIR223 MIR142 H2AC18
46	mature b-cell neoplasm	10.3	MIR185 MIR17 MIR142 H2AC18
47	rhabdoid meningioma	10.3	NF2 BAP1
48	intestinal benign neoplasm	10.3	MIR17 MIR142 MIR139 H2AC18
49	benign peritoneal mesothelioma	10.3	MSLN CALB2
50	gastrointestinal system benign neoplasm	10.3	MIR17 MIR142 MIR139 H2AC18

Comorbidity relations with Pleural Cancer via Phenotypic Disease Network (PDN):

Deficiency Anemia

Graphical network of the top 20 diseases related to Pleural Cancer:

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Symptoms & Phenotypes for Pleural Cancer

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Drugs & Therapeutics for Pleural Cancer

Drugs for Pleural Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Pemetrexed

Approved, Investigational

Phase 2

150399-23-8, 137281-23-3

446556 60843

Synonyms:

(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

(2R)-2-{[4-(2-{4-hydroxy-2-imino-1H,2H,7H-pyrrolo[2,3-D]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate

(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

137281-23-3

150399-23-8

1juj

2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID

AC1L1U1D

AC1L2PDW

AC1L98DY

AC1L9JT6

AC1OCF51

AC1Q5R1W

Alimta

ALIMTA

Alimta (TN)

Bio-0078

C20H19N5O6.2Na

C20H21N5O6

CHEBI:195145

CHEBI:43746

CHEBI:474008

CHEMBL1200373

CHEMBL225072

CHEMBL59843

CID125891

CID394493

CID446556

CID60843

CID6918197

D03828

D07472

DB00642

disodium (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

disodium (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

Disodium N-(p-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate

Disodium, pemetrexed

HSDB 7316

I06-1253

I06-1294

I06-2128

L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-, disodium salt

LS-172988

LS-173384

LY 231,514

LY 231514

LY-231,514

LY-2315

LY231514

LY-231514

LY231514 disodium

LYA

MTA

N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid

N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-D)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid

n-{4-[2-(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-d-glutamic acid

NCGC00167517-01

nchembio.108-comp6

NCI60_035021

NSC698037

Pemetrexed

Pemetrexed (INN)

Pemetrexed [INN:BAN]

Pemetrexed disodium

Pemetrexed Disodium

Pemetrexed disodium (USAN)

Pemetrexed disodium [USAN]

Rolazar

ST51053024

Tifolar

UNII-04Q9AIZ7NO

UNII-2PKU919BA9

Levoleucovorin

Approved, Investigational

Phase 2

68538-85-2

149436

Synonyms:

(6S)-5-Formyl-5,6,7,8-tetrahydrofolate

(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid

(6S)-5-Formyltetrahydrofolate

(6S)-5-formyltetrahydrofolic acid

(6S)-5-Formyltetrahydrofolic acid

(6S)-Folinate

(6S)-Folinic acid

(6S)-Leucovorin

(S)-Leucovorin

5 Formyltetrahydrofolate

5 Formyltetrahydropteroylglutamate

5-Formyl-(6S)-tetrahydrofolic acid

5-Formyl-5,6,7,8-tetrahydrofolic acid

5-Formyltetrahydrofolate

5-Formyltetrahydrofolic acid

5-Formyltetrahydropteroylglutamate

5-Formyltetrahydropteroylglutamic acid

6 S Leucovorin

6S Leucovorin

6S-Leucovorin

6-S-Leucovorin

Acid, folinic

ácido levofolínico

Calcium folinate

Calcium leucovorin

Citrovorum factor

Factor, citrovorum

Folinate

Folinate, calcium

Folinic acid

Folinic acid SF

Folinic acid-SF

Fusilev

Kunyrin

Leucoverin

Leucovorin

Leucovorin, (D)-isomer

Leucovorin, (DL)-isomer

Leucovorin, (R)-isomer

Leucovorin, (S)-isomer

Leucovorin, calcium

Leucovorin, calcium (1:1) salt

Leucovorin, calcium (1:1) salt, (DL)-isomer

Leucovorin, calcium (1:1) salt, (S)-isomer

Leucovorin, calcium (1:1) salt, pentahydrate

Leucovorin, monopotassium salt, (S)-isomer

Leucovorin, monosodium salt

Leucovorin, monosodium salt, (S)-isomer

Leukovorin

Leukovorum

Levo leucovorin

Levofolene

Levofolinate

Levofolinic acid

Levoleucovorin

Levo-leucovorin

L-Folinate

L-Folinic acid

Monosodium salt leucovorin

N(5)-Formyltetrahydrofolate

N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate

N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid

N5-Formyl-5,6,7,8-tetrahydrofolic acid

N5-Formyltetrahydrofolic acid

N5-Formyl-THF

Pteroyl-D-glutamate

S Leucovorin

S-Leucovorin

Welcovorin

Wellcovorin

Cisplatin

Approved

Phase 2

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatin

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Aminolevulinic acid

Approved

Phase 2

106-60-5

137

Synonyms:

106-60-5

35BEC718-C970-426A-9859-BF58284C60B4

5 Aminolaevulinate

5 Aminolevulinate

5451-09-2

5-ALA

5-Amino-4-oxopentanoate

5-Amino-4-oxo-pentanoate

5-Amino-4-oxopentanoic acid

5-Amino-4-oxo-pentanoic acid

5-Amino-4-oxovalerate

5-Amino-4-oxovaleric acid

5-Aminolaevulinate

5-Aminolaevulinic acid

5-amino-levulinate

5-Aminolevulinate

5-Amino-levulinate

5-Aminolevulinic acid

5-Amino-levulinic acid

AC-054

AC1L18K9

Acid hydrochloride, aminolevulinic

Acid, aminolevulinic

Acid, Delta-aminolevulinic

ácido 5-aminolevulínico

AKOS003587520

Aladerm

Aminolevulinate

Aminolevulinic

Aminolevulinic acid

Amino-levulinic acid

Aminolevulinic acid hydrochloride

Bertek brand OF aminolevulinic acid hydrochloride

BIDD:GT0260

BSPBio_003407

C00430

CCRIS 8958

CHEBI:17549

CHEMBL601

CID137

CPD000857229

D07567

dALA

DALA

DB00855

Delta Aminolevulinic acid

delta-ALA

delta-Aminolevulinate

delta-aminolevulinic acid

delta-Aminolevulinic acid

DivK1c_006954

EINECS 203-414-1

Hydrochloride, aminolevulinic acid

I14-10101

KBio1_001898

KBio2_002062

KBio2_004630

KBio2_007198

KBio3_002627

KBioGR_001176

KBioSS_002062

Kerastick

Levulan

Levulinic acid, 5-amino- (8CI)

LMFA01100055

LS-101793

MLS001333097

MLS001333098

MolPort-001-788-423

NCGC00178086-01

Pentanoic acid, 5-amino-4-oxo- (9CI)

SAM002589919

SMR000857229

SPBio_001843

SpecPlus_000858

Spectrum_001582

Spectrum2_001662

Spectrum3_001654

Spectrum4_000618

Spectrum5_001505

ST50819610

UNII-88755TAZ87

δ-ALA

Δ-ala

Δ-aminolevulinate

δ-aminolevulinic acid

Δ-aminolevulinic acid

nivolumab

Approved

Phase 2

946414-94-4

Folic acid

Approved, Nutraceutical, Vet_approved

Phase 2

59-30-3

6037

Synonyms:

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

01769_FLUKA

2d0k

33609-88-0

36653-55-1 (mono-potassium salt)

59-30-3

6484-89-5 (mono-hydrochloride salt)

AC-11682

AC1L1LNX

Acfol (Spain)

Acide folique

Acide folique [INN-French]

Acido folico

ácido fólico

Acido folico [INN-Spanish]

Acidum folicum

Acidum folicum [INN-Latin]

Acifolic

AI3-26387

AKOS000503224

Antianemia factor

Apo-Folic

ARONIS014410

b9, Vitamin

BIDD:ER0563

BIDD:GT0641

BIF0608

bmse000299

BPBio1_000654

BSPBio_000594

BSPBio_002338

C00504

C20H20N6O6

CAS-59-30-3

CCRIS 666

CHEBI:27470

CHEMBL1622

CID6037

CPD000471860

Cytofol

D00070

DB00158

DivK1c_000494

Dosfolat b activ

Dosfolat B activ

EINECS 200-419-0

F0043

F7876_SIAL

F7876_SIGMA

F8758_SIGMA

F8798_SIAL

F8890_SIGMA

Facid

Factor U

FOL

Folacid

Folacin

Folaemin

Folaemin [Netherlands]

Folan

Folasic (Australia)

Folate

Folbal

Folcidin

Folcidin (VAN)

Folcysteine

Foldine

Foldine [France]

Folettes

Foliamin

Folic

folic acid

Folic acid

Folic acid (JP15/USP/INN)

Folic acid (TN)

Folic acid [BAN:INN:JAN]

Folic acid [INN:BAN:JAN]

Folic acid dihydrate

Folic acid, (D)-isomer

Folic acid, (DL)-isomer

Folic acid, calcium salt (1:1)

Folic acid, monopotassium salt

Folic acid, monosodium salt

Folic acid, potassium salt

Folic acid, sodium salt

Folicet

Folicet (TN)

Folico

Folico (Italy)

Folina

Folina (Italy)

Folipac

Folsaeure

Folsan

Folsaure

Folsäure

Folsav

Folvite

Folvron

Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L

HMS1921D20

HMS2092N17

HMS501I16

HSDB 2002

IDI1_000494

Incafolic

InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s

KBio1_000494

KBio2_001861

KBio2_004429

KBio2_006997

KBio3_001558

KBioGR_002222

KBioSS_001861

Kyselina listova

Kyselina listova [Czech]

Liver lactobacillus casei factor

Liver Lactobacillus casei factor

LS-2157

Millafol

Mission prenatal

Mittafol

MLS001304016

MLS001335861

MolPort-004-285-551

N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid

N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

NCGC00016265-01

NCGC00142391-01

nchembio.108-comp10

Nifolin

Nifolin [Denmark]

NINDS_000494

Novofolacid

Novofolacid [Canada]

N-Pteroyl-L-glutamate

N-pteroyl-L-glutamic acid

N-Pteroyl-L-glutamic acid

NSC 3073

PGA

PGA (VAN)

Prestwick_230

Prestwick3_000627

PteGlu

Pteroylglutamate

Pteroylglutamic acid

Pteroyl-L-glutamate

Pteroyl-L-glutamic acid

Pteroyl-L-monoglutamate

Pteroyl-L-monoglutamic acid

Pteroylmonoglutamate

Pteroylmonoglutamic acid

SAM002264616

SDCCGMLS-0066738.P001

Serum Folate Level

SMP2_000137

SMR000471860

SPBio_001357

Spectrum_001381

SPECTRUM1502020

Spectrum2_001459

Spectrum3_000749

Spectrum4_001751

Spectrum5_000602

UNII-935E97BOY8

Usaf cb-13

Vitamin B11

Vitamin b9

Vitamin B9

Vitamin Bc

Vitamin BC

Vitamin be

Vitamin Be

Vitamin m

Vitamin M

Protein Kinase Inhibitors

Phase 2

Imatinib Mesylate

Phase 2

220127-57-1

123596

Folic Acid Antagonists

Phase 2

Vitamin B Complex

Phase 2

Vitamin B9

Phase 2

Folate

Phase 2

Antineoplastic Agents, Immunological

Phase 2

Antibodies

Phase 2

Immunoglobulins

Phase 2

Photosensitizing Agents

Phase 2

Doxycycline

Approved, Investigational, Vet_approved

564-25-0

54671203

Synonyms:

(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AR,5S,5ar,6R,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

10597-92-9

17086-28-1 (mono-hydrate)

24390-14-5

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)

41411-66-9 (6-epimer, mono-hydrochloride)

564-25-0

5-Hydroxy-a-6-deoxytetracycline

5-Hydroxy-alpha-6-deoxytetracycline

5-hydroxy-α-6-deoxytetracycline

5-Hydroxy-α-6-deoxytetracycline

69935-17-7 (mono-hydrochloride, di-hydrate)

6a-Deoxy-5-oxytetracycline

6alpha-deoxy-5-oxytetracycline

6-alpha-deoxy-5-oxytetracycline

6alpha-Deoxy-5-oxytetracycline

6-alpha-Deoxy-5-oxytetracycline

6-Deoxyoxytetracycline

6-Deoxytetracycline

6α-deoxy-5-oxytetracycline

6Α-deoxy-5-oxytetracycline

7164-70-7

7264-10-0

94088-85-4 (calcium salt (1:2))

AB08 (*Fosfatex)

AC1NQXW7

AC1NS4CW

AC1NUYS8

AC1O8PYM

alpha-6-Deoxy-5-hydroxytetracycline

alpha-6-Deoxyoxytetracycline

alpha-Doxycycline

Alti-Doxycycline

Anhydrous doxycycline

Apo-Doxy

Atridox

Azudoxat

BCBcMAP01_000024

BIDD:GT0146

BMY-28689

BPBio1_000951

BSPBio_000863

BSPBio_001936

BU-3839T

C06973

CHEBI:50845

CHEMBL1433

CID5281011

CID5353597

CID5463943

CID6713981

CPD001550033

D07876

DB00254

Deoxymykoin

DivK1c_000345

DMSC (*Fosfatex)

Dossiciclina

Dossiciclina [DCIT]

Doxcycline anhydrous

DOXCYCLINE ANHYDROUS

Doxiciclina

Doxiciclina [INN-Spanish]

Doxiciclina [Italian]

Doxitard

Doxivetin

DOXY

Doxy-Caps

Doxycen

Doxychel

Doxychel (TN)

Doxycin

Doxycyclin

doxycycline

Doxycycline

Doxycycline (200mg/day) or Placebo

Doxycycline (anhydrous)

Doxycycline (INN)

Doxycycline (internal use)

Doxycycline (TN)

Doxycycline anhydrous

DOXYCYCLINE CALCIUM

Doxycycline hyclate

Doxycycline monohydrate

DOXYCYCLINE MONOHYDRATE

Doxycycline-Chinoin

Doxycyclinum

Doxycyclinum [INN-Latin]

Doxy-Puren

Doxysol

Doxy-Tabs

Doxytec

Doxytetracycline

EINECS 209-271-1

GS-3065 (*monohydrate)

HMS2090E06

HSDB 3071

Hydramycin

IDI1_000345

Investin

Jenacyclin

KBio1_000345

KBio2_001287

KBio2_003855

KBio2_006423

KBio3_001156

KBioGR_001133

KBioSS_001287

Liviatin

Lopac0_000405

LS-187766

LS-93868

MolPort-002-507-423

Monodox

Monodox (*monohydrate)

NCGC00161602-01

NCGC00161602-03

NCGC00161602-04

NCGC00167961-01

NCGC00179395-01

NINDS_000345

Novo-Doxylin

NSC633557

Nu-Doxycycline

Oracea

Prestwick0_000852

Prestwick1_000852

Prestwick2_000852

Prestwick3_000852

Ronaxan

SAM002589932

SMP1_000107

Spanor

SPBio_000246

SPBio_002784

Spectrum_000807

Spectrum2_000143

Spectrum3_000408

Spectrum4_000527

Spectrum5_000947

STOCK1N-34341

Supracyclin

UNII-334895S862

UPCMLD-DP021

UPCMLD-DP021:001

Vibramycin

Vibramycin (*monohydrate)

Vibramycin Novum

Vibramycine

Vibra-tabs

Vibravenos

Vivox (*Hyclate)

Anti-Infective Agents

Antiprotozoal Agents

Antiparasitic Agents

Anti-Bacterial Agents

Antimalarials

Interventional clinical trials:

(show all 16)

#	Name	Status	NCT ID	Phase	Drugs
1	A Pilot Study of the Safety, Efficacy, and Side Effects of Interventional Cryotherapy for the Eradication of Disease in the Pleural Space ("ICE PLS")	Terminated	NCT00747916	Phase 4
2	Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases	Completed	NCT00154388	Phase 2	Imatinib mesylate
3	A Multicenter Phase II Trial of Neo-Adjuvant Pemetrexed (Alimta) Plus Cisplatin Followed by Surgery and Radiation for Pleural Mesothelioma	Completed	NCT00087698	Phase 2	pemetrexed;cisplatin
4	Intrapleural Photodynamic Therapy by Video-Assisted Thoracoscopy Followed by Anti-PD-1 NIVOLUMAB in Patients With Malignant Pleural Mesothelioma - a Pilot Study	Not yet recruiting	NCT04400539	Phase 2	Nivolumab Injection
5	PET Biodistribution Study of 68Ga-FAPI-46 in Patients With Different Malignancies: An Exploratory Biodistribution Study With Histopathology Validation	Recruiting	NCT04459273	Phase 1	Gallium Ga 68 FAPi-46
6	Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura. A Multicenter Study.	Unknown status	NCT01694654
7	Detection and Characterization of Circulating Tumor Cells in Patients With Malignant Pleural Mesothelioma: Towards a New Phase in the Understanding of the Natural History of This Cancer?	Completed	NCT01776385
8	Preoperative Oncogeriatric Assessment for Thoracic Malignancies	Completed	NCT00591981
9	Detection of Clusters of Volatile Organic Compounds (VOC)in Patients With Different Lung Disorders by Ion Mobility Spectrometry. Different Clusters of VOC in the Diagnosis of Different Lung Disorders Using Ion Mobility Spectrometry	Recruiting	NCT00632307
10	A Prospective Observational Cohort Study of Indwelling Pleural Catheters Versus Indwelling Pleural Catheters Plus Doxycycline Pleurodesis for Treatment of Malignant Pleural Effusions	Recruiting	NCT03465774		Doxycycline
11	Embedded Palliative Care in the Management of Advanced Thoracic Malignancies	Recruiting	NCT04662645
12	Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma	Recruiting	NCT02613312
13	Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma	Recruiting	NCT02613299
14	Staging Procedures to Diagnose Malignant Pleural Mesothelioma	Recruiting	NCT02648763
15	Mini Invasive Probe Based Confocal Laser Endomicroscopy of the Pleura for Malignancies Diagnosis	Recruiting	NCT04731129
16	Optical Coherence Tomography for Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer	Withdrawn	NCT00581503

Search NIH Clinical Center for Pleural Cancer

Cochrane evidence based reviews: pleural neoplasms

Sources

Genetic Tests for Pleural Cancer

Sources

Anatomical Context for Pleural Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Pleural Cancer:

¹⁹

Pleura

MalaCards organs/tissues related to Pleural Cancer:

⁴⁰

Heart, Lung, Prostate, Smooth Muscle, Testis

Sources

Publications for Pleural Cancer

Articles related to Pleural Cancer:

(show top 50) (show all 240)

#	Title	Authors	PMID	Year
1	Comments on a recent case-control study of malignant mesothelioma of the pericardium and the tunica vaginalis testis. ⁶¹	Mezei G...Moolgavkar SH	32626907	2021
2	TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response. ⁶¹	Yi FS...Shi HZ	33046503	2020
3	Solitary Fibrous Tumors Of The Pleura - 20-Year Experience. ⁶¹	Nawojowska A...Felix F	33280305	2020
4	Association between proximity to industrial chemical installations and cancer mortality in Spain. ⁶¹	Ayuso-Alvarez A...Fernandez-Navarro P	31991345	2020
5	Relative burden of lung and pleural cancers from exposure to asbestos: a cross-sectional analysis of occupational mortality in England and Wales. ⁶¹	Harris EC...Coggon D	32273321	2020
6	Mortality and mesothelioma incidence among chrysotile asbestos miners in Balangero, Italy: A cohort study. ⁶¹	Ferrante D...Magnani C	31821579	2020
7	Role of asbestos clearance in explaining long-term risk of pleural and peritoneal cancer: a pooled analysis of cohort studies. ⁶¹	Barone-Adesi F...Working Group	31413184	2019
8	Quantitative relationships of exposure to chrysotile asbestos and mesothelioma mortality. ⁶¹	Loomis D...Elliott L	31087402	2019
9	Occupational exposures to cosmetic talc and risk of mesothelioma: an updated pooled cohort and statistical power analysis with consideration of latency period. ⁶¹	Marsh GM...Finley BL	31380702	2019
10	Mortality for Mesothelioma and Lung Cancer in a Cohort of Asbestos Cement Workers in BARI (Italy): Time Related Aspects of Exposure. ⁶¹	Cuccaro F...Magnani C	30870398	2019
11	Extra-pleural pneumonectomy. ⁶¹	Duranti L...Pastorino U	31019792	2019
12	Cancer risk in oil refinery workers: a pooled mortality study in Italy. ⁶¹	Bonzini M...Pesatori CA	30794243	2019
13	Upcoming epidemic of asbestos-related malignant pleural mesothelioma in Taiwan: A prediction of incidence in the next 30 years. ⁶¹	Lin RT...Lee LJ	30072200	2019
14	Ratio of carcinoembryonic antigen in pleural fluid and serum for the diagnosis of malignant pleural effusion. ⁶¹	Hackner K...Handzhiev S	31205509	2019
15	Mortality among workers exposed to asbestos at the shipyard of Genoa, Italy: a 55 years follow-up. ⁶¹	Merlo DF...Ceppi M	30594195	2018
16	International Analysis of Age-Specific Mortality Rates From Mesothelioma on the Basis of the International Classification of Diseases, 10th Revision. ⁶¹	Boffetta P...La Vecchia C	30241199	2018
17	Immune-mediated Pericarditis With Pericardial Tamponade During Nivolumab Therapy. ⁶¹	de Almeida DVP...Buzaid AC	29461982	2018
18	The Diagnosis of Pleural Tumors Other Than Mesothelioma. ⁶¹	Attanoos RL...Pugh MR	30040453	2018
19	Transcervical videomediastino-thoracoscopy. ⁶¹	Belda-Sanchis J...Rami-Porta R	30345101	2018
20	MR Imaging of Pleural Neoplasms. ⁶¹	Carter BW...Lichtenberger JP	29613962	2018
21	[Health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy)]. ⁶¹	Caputo A...Comba P	29774711	2018
22	Mortality in a cohort of asbestos-exposed workers undergoing health surveillance. ⁶¹	Barbiero F...Barbone F	29701625	2018
23	Surgical therapy and next-generation sequencing-based genetic alteration analysis of malignant solitary fibrous tumor of the pleura. ⁶¹	Song Z...Ye Y	30214228	2018
24	Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms. ⁶¹	Venkatachala S...Padilu R	30697290	2018
25	Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure. ⁶¹	Ferrante D...the working group	28775133	2017
26	Chimeric Antigen Receptor (CAR) T Cell Therapy for Malignant Pleural Mesothelioma (MPM). ⁶¹	Klampatsa A...Albelda SM	28862644	2017
27	Application of Immunohistochemistry in the Diagnosis of Pulmonary and Pleural Neoplasms. ⁶¹	Woo JS...Xu H	28644685	2017
28	Mortality from cancer and other causes among Italian chrysotile asbestos miners. ⁶¹	Pira E...Boffetta P	28438787	2017
29	Mortality of Talc Miners and Millers From Val Chisone, Northern Italy: An Updated Cohort Study. ⁶¹	Pira E...Boffetta P	28691999	2017
30	A Proteomic Analysis of the Malignant Mesothelioma Secretome Using iTRAQ. ⁶¹	Creaney J...Robinson BW	28387650	2017
31	Solitary Fibrous Tumor - Less Common Neoplasms of the Pleural Cavity. ⁶¹	Vejvodova S...Vodicka J	28049955	2017
32	Malignant pleural fluid from mesothelioma has potent biological activities. ⁶¹	Cheah HM...Lee YC	27560254	2017
33	Updated mortality study of a cohort of asbestos textile workers. ⁶¹	Pira E...Boffetta P	27457053	2016
34	[Pleural mesothelioma mortality in Italy: time series reconstruction (1970-2009) and comparison with incidence (2003-2008)]. ⁶¹	Ferrante P...Marinaccio A	27436254	2016
35	Mortality (1968-2008) in a French cohort of uranium enrichment workers potentially exposed to rapidly soluble uranium compounds. ⁶¹	Zhivin S...Laurier D	26655962	2016
36	Metachronous Malignant Solitary Fibrous Tumor of Kidney: Case Report and Review of Literature. ⁶¹	Cheung F...Corcoran AT	26793578	2016
37	Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature. ⁶¹	Perrotta F...Mazzarella G	28352798	2016
38	Imaging characteristics of pleural tumours. ⁶¹	De Paoli L...Cova MA	26475741	2015
39	Survival patterns in lung and pleural cancer in Europe 1999-2007: Results from the EUROCARE-5 study. ⁶¹	Francisci S...EUROCARE-5 Working Group:	26421826	2015
40	Hemorrhagic intramedullary solitary fibrous tumor of the conus medullaris: case report. ⁶¹	Walker CT...Khalessi AA	26115022	2015
41	Risk of cancer from occupational exposure to ionising radiation: retrospective cohort study of workers in France, the United Kingdom, and the United States (INWORKS). ⁶¹	Richardson DB...Kesminiene A	26487649	2015
42	Pleural neoplastic pathology. ⁶¹	Karpathiou G...Froudarakis ME	26048082	2015
43	Cancer incidence among 41,000 offshore oil industry workers. ⁶¹	Stenehjem JS...Grimsrud TK	25082833	2014
44	Spatial relationship quantification between environmental, socioeconomic and health data at different geographic levels. ⁶¹	Saib MS...Cicolella A	24705362	2014
45	Retrospective cohort study of a microelectronics and business machine facility. ⁶¹	Silver SR...Bertke SJ	24375784	2014
46	A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. ⁶¹	Ruppen J...Guenat OT	24496222	2014
47	Solitary fibrous tumor of the intrathoracic goiter. ⁶¹	Vaziri M...Tamannaei Z	25405117	2014
48	The fibres with fluoro-edenitic composition in Biancavilla (Sicily, Italy): health impact and clues for environmental remediation. ⁶¹	Comba P...Musmeci L	24968907	2014
49	Positive FDG-PET/CT of the pleura twenty years after talc pleurodesis: three cases of benign talcoma. ⁶¹	Vandemoortele T...Astoul P	24457915	2014
50	A tailored, supportive care intervention using systematic assessment designed for people with inoperable lung cancer: a randomised controlled trial. ⁶¹	Schofield P...Aranda S	23733720	2013

Sources

Genes for Pleural Cancer

Genes related to Pleural Cancer (0 elite genes):

(show all 36)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	12.11	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	MIR625	MicroRNA 625	RNA Gene	10.23	DISEASES inferred ¹⁵ ¹⁵
3	MIR32	MicroRNA 32	RNA Gene	9.86	DISEASES inferred ¹⁵ ¹⁵
4	MIR193A	MicroRNA 193a	RNA Gene	9.78	DISEASES inferred ¹⁵ ¹⁵
5	MIR29C	MicroRNA 29c	RNA Gene	9.53	DISEASES inferred ¹⁵ ¹⁵
6	MIR17	MicroRNA 17	RNA Gene	8.8	DISEASES inferred ¹⁵ ¹⁵
7	MIR223	MicroRNA 223	RNA Gene	8.56	DISEASES inferred ¹⁵ ¹⁵
8	MSLN	Mesothelin	Protein Coding	8.38	DISEASES inferred ¹⁵
9	MIR411	MicroRNA 411	RNA Gene	8.35	DISEASES inferred ¹⁵ ¹⁵
10	MIR138-1	MicroRNA 138-1	RNA Gene	8.29	DISEASES inferred ¹⁵ ¹⁵
11	MIR30E	MicroRNA 30e	RNA Gene	8.24	DISEASES inferred ¹⁵ ¹⁵
12	MIR142	MicroRNA 142	RNA Gene	7.76	DISEASES inferred ¹⁵ ¹⁵
13	MIR93	MicroRNA 93	RNA Gene	7.76	DISEASES inferred ¹⁵ ¹⁵
14	MIRLET7A1	MicroRNA Let-7a-1	RNA Gene	7.76	DISEASES inferred ¹⁵ ¹⁵
15	H2AC18	H2A Clustered Histone 18	Protein Coding	7.71	DISEASES inferred ¹⁵ ¹⁵
16	CALB2	Calbindin 2	Protein Coding	7.71	DISEASES inferred ¹⁵
17	MIR185	MicroRNA 185	RNA Gene	7.46	DISEASES inferred ¹⁵ ¹⁵
18	MIR139	MicroRNA 139	RNA Gene	7.29	DISEASES inferred ¹⁵ ¹⁵
19	BAP1	BRCA1 Associated Protein 1	Protein Coding	7.25	DISEASES inferred ¹⁵
20	NF2	Neurofibromin 2	Protein Coding	7.07	DISEASES inferred ¹⁵
21	GART	Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase	Protein Coding	7.04	DISEASES inferred ¹⁵
22	MIR200A	MicroRNA 200a	RNA Gene	6.73	DISEASES inferred ¹⁵ ¹⁵
23	EFEMP1	EGF Containing Fibulin Extracellular Matrix Protein 1	Protein Coding	6.66	DISEASES inferred ¹⁵
24	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	6.65	DISEASES inferred ¹⁵
25	TYMS	Thymidylate Synthetase	Protein Coding	6.58	DISEASES inferred ¹⁵
26	EGFR	Epidermal Growth Factor Receptor	Protein Coding	6.58	DISEASES inferred ¹⁵
27	CD274	CD274 Molecule	Protein Coding	6.52	DISEASES inferred ¹⁵
28	TP53	Tumor Protein P53	Protein Coding	6.49	DISEASES inferred ¹⁵
29	WT1	WT1 Transcription Factor	Protein Coding	6.49	DISEASES inferred ¹⁵
30	KRT5	Keratin 5	Protein Coding	6.44	DISEASES inferred ¹⁵
31	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	6.31	DISEASES inferred ¹⁵
32	SPP1	Secreted Phosphoprotein 1	Protein Coding	6.26	DISEASES inferred ¹⁵
33	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	6.18	DISEASES inferred ¹⁵
34	MTAP	Methylthioadenosine Phosphorylase	Protein Coding	6.13	DISEASES inferred ¹⁵
35	CD8A	CD8a Molecule	Protein Coding	6.08	DISEASES inferred ¹⁵
36	DHFR	Dihydrofolate Reductase	Protein Coding	6.06	DISEASES inferred ¹⁵

Sources

Variations for Pleural Cancer

Sources

Expression for Pleural Cancer

Search GEO for disease gene expression data for Pleural Cancer.

Sources

Pathways for Pleural Cancer

Pathways related to Pleural Cancer according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	MicroRNAs in cancer ³⁶	11.66	MIRLET7A1 MIR625 MIR32 MIR30E MIR29C MIR223

Sources

GO Terms for Pleural Cancer

Cellular components related to Pleural Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.77	MUC16 MSLN MIRLET7A1 MIR93 MIR625 MIR411
2	extracellular vesicle	GO:1903561	9.23	MIRLET7A1 MIR93 MIR411 MIR30E MIR29C MIR193A

Biological processes related to Pleural Cancer according to GeneCards Suite gene sharing:

(show all 13)

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of cell proliferation	GO:0008285	9.85	NF2 MIR93 MIR29C MIR138-1 BAP1
2	negative regulation of gene expression	GO:0010629	9.72	MIR93 MIR29C MIR185 MIR17 MIR138-1
3	negative regulation of inflammatory response	GO:0050728	9.7	MIR223 MIR142 MIR138-1
4	negative regulation of angiogenesis	GO:0016525	9.69	MIR29C MIR193A MIR185
5	negative regulation of cell migration	GO:0030336	9.67	NF2 MIR93 MIR29C MIR138-1
6	negative regulation of G1/S transition of mitotic cell cycle	GO:2000134	9.61	MIR29C MIR193A MIR138-1
7	negative regulation of cell-matrix adhesion	GO:0001953	9.49	NF2 MIR29C
8	negative regulation of low-density lipoprotein particle clearance	GO:0010989	9.48	MIR185 MIR17
9	gene silencing by miRNA	GO:0035195	9.47	MIRLET7A1 MIR93 MIR625 MIR411 MIR32 MIR30E
10	negative regulation of sprouting angiogenesis	GO:1903671	9.43	MIR30E MIR17 MIR138-1
11	negative regulation of vascular associated smooth muscle cell apoptotic process	GO:1905460	9.4	MIR17 MIR138-1
12	negative regulation of vascular endothelial cell proliferation	GO:1905563	9.33	MIR30E MIR29C MIR193A
13	miRNA mediated inhibition of translation	GO:0035278	9.26	MIRLET7A1 MIR29C MIR17 MIR138-1

Molecular functions related to Pleural Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mRNA binding involved in posttranscriptional gene silencing	GO:1903231	9.44	MIRLET7A1 MIR93 MIR411 MIR32 MIR30E MIR29C
2	mRNA 3'-UTR binding	GO:0003730	9.43	MIR93 MIR29C MIR193A MIR17 MIR142 MIR139

Sources

Sources for Pleural Cancer

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia