MCID: PLR005
MIFTS: 43

Pleuropneumonia

Categories: Respiratory diseases

Aliases & Classifications for Pleuropneumonia

MalaCards integrated aliases for Pleuropneumonia:

Name: Pleuropneumonia 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:14319
MeSH 44 D011001
SNOMED-CT 68 60485005
UMLS 73 C0032241

Summaries for Pleuropneumonia

Disease Ontology : 12 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards based summary : Pleuropneumonia is related to thrombophlebitis and urethritis. An important gene associated with Pleuropneumonia is SNORD50A (Small Nucleolar RNA, C/D Box 50A), and among its related pathways/superpathways are Akt Signaling and IL-2 Pathway. The drugs Doxycycline and Lymecycline have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin, and related phenotypes are cellular and hematopoietic system

Wikipedia : 76 Pleuropneumonia is inflammation of the lungs and pleura, pleurisy being the inflammation of the pleura... more...

Related Diseases for Pleuropneumonia

Diseases related to Pleuropneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 thrombophlebitis 29.5 PLAT SERPINC1
2 urethritis 10.3
3 arthritis 10.2
4 pneumonia 10.2
5 post-cardiac arrest syndrome 10.2 IRAK3 IRAK4
6 hemoglobin lepore-beta-thalassemia syndrome 10.2 HBB HBD
7 hemoglobin d disease 10.2 HBB HBD
8 malignant secondary hypertension 10.1 HBB HBD
9 hemoglobin c disease 10.1 HBB HBD
10 hemoglobin e disease 10.1 HBB HBD
11 osgood-schlatter's disease 10.1 HBB HBD
12 fetal hemoglobin quantitative trait locus 1 10.1 HBB HBD
13 kluver-bucy syndrome 10.1 HBB HBD
14 bacterial infectious disease 10.1 IRAK1 IRAK4 MYD88
15 waldenstroem's macroglobulinemia 10.1 CD19 MYD88
16 malignant essential hypertension 10.1 HBB HBD
17 gamma heavy chain disease 10.1 CD19 MYD88
18 cold urticaria 10.0 IL1R1 SERPINC1
19 swine influenza 10.0
20 rhinitis 10.0
21 atrophic rhinitis 10.0
22 influenza 10.0
23 haemophilus influenzae 10.0
24 fibrinolytic defect 10.0 PLAT SERPINC1
25 argentine hemorrhagic fever 10.0 PLAT SERPINC1
26 plasma protein metabolism disease 10.0 CD19 MYD88
27 intracranial embolism 10.0 PLAT SERPINC1
28 platelet aggregation, spontaneous 10.0 PLAT SERPINC1
29 posterior myocardial infarction 10.0 PLAT SERPINC1
30 blind loop syndrome 10.0 HBB HBD
31 encephalopathy, familial, with neuroserpin inclusion bodies 10.0 PLAT SERPINC1
32 non-secretory myeloma 10.0 CD19 CXCL9
33 marantic endocarditis 9.9 PLAT SERPINC1
34 hepatitis 9.9
35 sinusitis 9.9
36 pertussis 9.9
37 cystitis 9.9
38 pericarditis 9.9
39 synovitis 9.9
40 peritonitis 9.9
41 meningitis 9.9
42 blood protein disease 9.9 HBB HBD SERPINC1
43 diaphragmatic hernia, congenital 9.8
44 rheumatoid arthritis 9.8
45 asthma 9.8
46 leukemia, acute lymphoblastic 9.8
47 b-cell lymphomas 9.8
48 diffuse large b-cell lymphoma 9.8
49 leukemia 9.8
50 ulcerative colitis 9.8

Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to Pleuropneumonia

Symptoms & Phenotypes for Pleuropneumonia

MGI Mouse Phenotypes related to Pleuropneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.91 CD19 COL18A1 GGT1 IL1R1 IRAK1 IRAK4
2 hematopoietic system MP:0005397 9.81 CD19 GGT1 IL1R1 IRAK1 IRAK3 IRAK4
3 immune system MP:0005387 9.61 CD19 GGT1 IL1R1 IRAK1 IRAK3 IRAK4
4 renal/urinary system MP:0005367 9.1 CD19 COL18A1 GGT1 IL1R1 MYD88 SERPINC1

Drugs & Therapeutics for Pleuropneumonia

Drugs for Pleuropneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 131)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 564-25-0 54671203
2
Lymecycline Approved, Investigational Phase 4 992-21-2 5280963
3
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
4
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
5
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
6
Ofloxacin Approved Phase 4 82419-36-1 4583
7
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
8
Prednisolone phosphate Approved, Vet_approved Phase 4,Not Applicable 302-25-0
9
Methylprednisolone hemisuccinate Approved Phase 4,Not Applicable 2921-57-5
10
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
11
Prednisolone hemisuccinate Experimental Phase 4,Not Applicable 2920-86-7
12 Antimalarials Phase 4,Phase 3,Phase 2,Not Applicable
13 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
14 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
15 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Not Applicable
16 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
17 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
18 Antitubercular Agents Phase 4,Phase 3,Phase 2,Not Applicable
19 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
20 Peripheral Nervous System Agents Phase 4,Not Applicable
21 Anti-Inflammatory Agents Phase 4,Not Applicable
22 Gastrointestinal Agents Phase 4,Phase 2,Not Applicable
23 Anti-Infective Agents, Urinary Phase 4,Phase 2
24 Topoisomerase Inhibitors Phase 4,Not Applicable
25 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
26 Renal Agents Phase 4,Phase 2
27 Autonomic Agents Phase 4,Not Applicable
28 Methylprednisolone acetate Phase 4,Not Applicable
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
30 Hormone Antagonists Phase 4,Not Applicable
31 Antineoplastic Agents, Hormonal Phase 4,Not Applicable
32 Protective Agents Phase 4,Not Applicable
33 Prednisolone acetate Phase 4,Not Applicable
34 Neuroprotective Agents Phase 4,Not Applicable
35 Hormones Phase 4,Not Applicable
36 glucocorticoids Phase 4,Not Applicable
37 Antiemetics Phase 4,Not Applicable
38 Laxatives Phase 4
39 Carboxymethylcellulose Sodium Phase 4
40 Cathartics Phase 4
41
Clarithromycin Approved Phase 3,Phase 2 81103-11-9 84029
42
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
43
Cefixime Approved, Investigational Phase 3 79350-37-1 5362065 54362
44
Josamycin Investigational Phase 3 16846-24-5 5282165
45 Cytochrome P-450 CYP3A Inhibitors Phase 3,Phase 2
46 Cephalosporins Phase 3,Not Applicable
47 beta-Lactams Phase 3
48 Lactams Phase 3
49
Basiliximab Approved, Investigational Phase 2 152923-56-3, 179045-86-4
50
Infliximab Approved Phase 2 170277-31-3

Interventional clinical trials:

(show top 50) (show all 67)
# Name Status NCT ID Phase Drugs
1 Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner Unknown status NCT01555047 Phase 4
2 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4 Azithromycin;Doxycycline;lymecycline
3 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
4 Microorganism in Overactive Bladder Patients Completed NCT00883818 Phase 4 azithromycin, doxycycline
5 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
6 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4 Prednisolone;Levofloxacin
7 Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study Terminated NCT01879930 Phase 4 doxycycline;placebo
8 Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis Unknown status NCT01652118 Phase 3 clarithromycin treatment for prophylaxis of bronchopulmonary dysplasia;Saline
9 Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA) Completed NCT00358462 Phase 3 Azithromycin;Doxycycline
10 Antibiotic Treatment of Gulf War Veterans' Illnesses Completed NCT00007735 Phase 3 Doxycycline (200mg/day) or Placebo
11 Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin) Completed NCT00718705 Phase 3 Josamycin;Placebo
12 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3 Ceftaroline fosamil for Injection;Ceftriaxone;Placebo
13 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3 Ceftaroline fosamil for Injection;IV Ceftriaxone;Placebo;Clarithromycin
14 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
15 TINN2: Treat Infection in NeoNates 2 Withdrawn NCT02282176 Phase 3 Azithromycin;Placebo
16 Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease Unknown status NCT02770430 Phase 2 conventional treatment
17 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2 Azithromycin;Placebo
18 A Web-based Intervention Study to Reduce High-risk Sexual Behavior by Persons Living With HIV AIDS (PLWH) Completed NCT01198418 Phase 1, Phase 2
19 NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole) Completed NCT00322465 Phase 2 Tinidazole;Doxycycline;Azithromycin
20 Autologous Dendritic Cell Vaccination in Mesothelioma Recruiting NCT02649829 Phase 1, Phase 2
21 Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients Recruiting NCT02649582 Phase 1, Phase 2
22 A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV Recruiting NCT03431168 Phase 2 Azithromycin/TMPS;Placebo/TMPS
23 Aralast NP in Islet Transplant Active, not recruiting NCT02520076 Phase 1, Phase 2 Alpha-1 Antitrypsin
24 Pharmacokinetic Study of Clarithromycin in Very Low Birth Weight (VLBW) Terminated NCT01851954 Phase 2 Clarithromycin
25 Mecillinam for Treatment of Genital Chlamydia Infection Terminated NCT02083276 Phase 2 Pivmecillinamhydrochlorid
26 NSAIDs Treatment in Children With Pleuropneumonia Unknown status NCT01586299 Not Applicable Ibuprofen;Acetaminophen
27 Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy Unknown status NCT01281319
28 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
29 Personalized Immunotherapeutic for Antibiotic-resistant Infection Unknown status NCT02508584 Early Phase 1
30 Etiology Study of Kawasaki Disease Unknown status NCT00154596
31 The Role of Viral Infection in Acute Exacerbations of Non-cystic Fibrosis Bronchiectasis in Adults Unknown status NCT01801657
32 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Not Applicable Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
33 300 Antibody Diagnostic Test Kit Unknown status NCT01646411
34 Detection of Mycoplasma Pneumoniae Completed NCT02511262
35 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
36 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584 Not Applicable Doxycycline treatment
37 Evaluation of Pathogenesis and Diagnosis of Mycoplasma Pneumoniae Community-acquired Pneumonia (CAP) Completed NCT03613636
38 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141 Not Applicable Moxifloxacin;Cephalosporins and azithromycin
39 Colonization of the Female Urethra With Mycoplasma Hominis, Ureaplasma Urealyticum, Chlamydia Trachomatis, or Neisseria Gonorrhea in Patients With Lower Urinary Tract Symptoms Completed NCT01559623
40 Etiology of Community Acquired Pneumonia Completed NCT00471757
41 Community-Acquired Pneumonia (CAP) Surveillance Completed NCT01416506
42 Evaluation of the Use of the Colli-Pee Device to Collect First-void Urine for Molecular Detection of STIs Completed NCT02552914
43 Infections and Pregnancy Loss: Correlation Between Abortion and Silent Infections. Completed NCT03585023
44 Rewarding Sexually Transmitted Infection (STI) Prevention and Control in Tanzania Completed NCT00922038 Not Applicable
45 Clinical Efficacy of Roxithromycin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome Completed NCT01843946
46 Levofloxacin in Bacterial Rhinosinussitis Completed NCT02712502 Levofloxacin;Amoxicillin-Potassium Clavulanate Combination
47 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
48 Use of Non Steroidal Antiinflammatory Drugs in Patients With Community Acquired Pneumonia Completed NCT02523885
49 Collecting and Storing Tissue From Young Patients With Cancer Completed NCT00898755
50 Treatment of Macrolide-resistant Mycoplasma Pneumoniae Recruiting NCT03530319 Not Applicable Doxycycline;Azithromycin

Search NIH Clinical Center for Pleuropneumonia

Cochrane evidence based reviews: pleuropneumonia

Genetic Tests for Pleuropneumonia

Anatomical Context for Pleuropneumonia

MalaCards organs/tissues related to Pleuropneumonia:

41
Lung, Testes, Skin, Kidney, T Cells, B Cells, Prostate

Publications for Pleuropneumonia

Articles related to Pleuropneumonia:

(show top 50) (show all 737)
# Title Authors Year
1
Perceptions, circumstances and motivators affecting the implementation of contagious bovine pleuropneumonia control programmes in Nigerian Fulani pastoral herds. ( 29290302 )
2018
2
Improving quality control of Contagious Caprine Pleuropneumonia vaccine with tandem mass spectrometry. ( 29911326 )
2018
3
Polymorphonuclear cells and reactive oxygen species in contagious bovine pleuropneumonia: New insight from in vitro investigations. ( 29914676 )
2018
4
Contagious Bovine Pleuropneumonia: Seroprevalence and Risk Factors in Gimbo District, Southwest Ethiopia. ( 29977494 )
2018
5
Respiratory explants as a model to investigate early events of contagious bovine pleuropneumonia infection. ( 29329577 )
2018
6
Efficacy of a one-shot marbofloxacin treatment on acute pleuropneumonia after experimental aerosol inoculation of nursery pigs. ( 29977591 )
2018
7
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd. ( 30086851 )
2018
8
Contagious bovine pleuropneumonia within the 19th century miasmatic landscape. ( 30129029 )
2018
9
Serological Prevalence of Contagious Bovine Pleuropneumonia in Niger in 2017. ( 30370271 )
2018
10
Epidemiological investigations of contagious caprine pleuropneumonia in selected districts of Borana zone, Southern Oromia, Ethiopia. ( 30397847 )
2018
11
Mycoplasma capricolum subsp. capripneumoniae, the cause of contagious caprine pleuropneumonia, comprises two distinct biochemical groups. ( 30538929 )
2018
12
Lung lesion score system in cattle: proposal for contagious bovine pleuropneumonia. ( 28951993 )
2017
13
The value of molecular techniques to diagnose Ureaplasma urealyticum and Nocardia farcinica Pleuropneumonia in a Patient with Diffuse large B-Cell Lymphoma. ( 28951103 )
2017
14
Ultrasonographic findings in goats with contagious caprine pleuropneumonia caused by Mycoplasma capricolum subsp. capripneumoniae. ( 28830505 )
2017
15
B cell cross-epitope of Propionibacterium acnes and Actinobacillus pleuropneumonia selected by phage display library can efficiently protect from Actinobacillus pleuropneumonia infection. ( 28622855 )
2017
16
Policy analysis for delivery of contagious bovine pleuropneumonia control strategies in sub-Saharan Africa. ( 28926016 )
2017
17
Contagious caprine pleuropneumonia: The first isolation and molecular characterization of Mycoplasma capricolum subsp. capripneumoniae in the Kingdom of Saudi Arabia. ( 28111131 )
2017
18
Factors Associated with Survival in 97 Horses with Septic Pleuropneumonia. ( 28271546 )
2017
19
Thoracic splenosis mimicking a pleuropneumonia: A case report. ( 28723778 )
2017
20
Seroprevalence and Distribution of Contagious Bovine Pleuropneumonia in Ethiopia: Update and Critical Analysis of 20 Years (1996-2016) Reports. ( 28702460 )
2017
21
Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia. ( 27496744 )
2016
22
A meta-analysis of contagious caprine pleuropneumonia (CCPP) in Ethiopia. ( 26943994 )
2016
23
Community-acquired pleuropneumonia in children: Bacteriological and therapeutic challenges. ( 27704513 )
2016
24
Complete Genome Sequence of Mycoplasma mycoides subsp. mycoides T1/44, a Vaccine Strain against Contagious Bovine Pleuropneumonia. ( 27081135 )
2016
25
Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia. ( 26964722 )
2016
26
Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy. ( 27033917 )
2016
27
A contagious bovine pleuropneumonia outbreak on a research farm in Ethiopia, and its dynamics over an eight-month period. ( 28332650 )
2016
28
Morphological characterization and immunohistochemical detection of the proinflammatory cytokines IL-1I^, IL-17A, and TNF-I+ in lung lesions associated with contagious bovine pleuropneumonia. ( 26837619 )
2016
29
Contagious bovine pleuropneumonia: Seroprevalence and risk factors in Western Oromia, Ethiopia. ( 27247066 )
2016
30
Development of a Novel Cocktail Enzyme-Linked Immunosorbent Assay and a Field-Applicable Lateral-Flow Rapid Test for Diagnosis of Contagious Bovine Pleuropneumonia. ( 27053669 )
2016
31
Qualitative and quantitative impacts assessment of contagious bovine pleuropneumonia in Fulani pastoral herds of North-central Nigeria: The associated socio-cultural factors. ( 27237398 )
2016
32
Molecular detection of Nigerian field isolates of Mycoplasma mycoides subsp. mycoides as causative agents of contagious bovine pleuropneumonia. ( 30255039 )
2016
33
Therapeutic effect of Chinese patent medicine "Wuhuanghu" on porcine infectious pleuropneumonia and its acute and subchronic toxicity as well as evaluation of safety pharmacology. ( 26245812 )
2015
34
Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. ( 26384697 )
2015
35
Update on Bacterial Pneumonia and Pleuropneumonia in the Adult Horse. ( 25600453 )
2015
36
Sero-prevalence of Contagious Bovine Pleuropneumonia (CBPP) in bulls originated from Borena pastoral area of Southern Ethiopia. ( 25863957 )
2015
37
Streptococcus equi subsp zooepidemicus pleuropneumonia and peritonitis in a dromedary camel (Camelus dromedarius) calf in North America. ( 26176731 )
2015
38
Mathematical modelling of the transmission dynamics of contagious bovine pleuropneumonia reveals minimal target profiles for improved vaccines and diagnostic assays. ( 25668725 )
2015
39
Whole-Genome Sequencing of Mycoplasma mycoides subsp. mycoides Italian Strain 57/13, the Causative Agent of Contagious Bovine Pleuropneumonia. ( 25814605 )
2015
40
The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007-2012). ( 26256909 )
2015
41
Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP). ( 26476145 )
2015
42
Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali. ( 25433650 )
2015
43
Isolation and Phylogenetic Characterization of Streptococcus halichoeri from a European Badger (Meles meles) with Pyogranulomatous Pleuropneumonia. ( 25678424 )
2015
44
Non-haemolytic Mannheimia haemolytica as a cause of pleuropneumonia and septicemia in a calf. ( 26344042 )
2015
45
Abattoir surveillance demonstrates contagious bovine pleuropneumonia is widespread in Tanzania. ( 26315150 )
2015
46
Sero-positivity and associated risk factors for contagious bovine pleuropneumonia under two cattle production systems in North Central Nigeria. ( 26563271 )
2015
47
Quantitative risk assessment of entry of contagious bovine pleuropneumonia through live cattle imported from northwestern Ethiopia. ( 26427634 )
2015
48
The Association of Fibrinous Pleural Effusion with Survival and Complications in Horses with Pleuropneumonia (2002-2012): 74 Cases. ( 26259510 )
2015
49
Participatory Epidemiology of Ethnoveterinary Practices Fulani Pastoralists Used to Manage Contagious Bovine Pleuropneumonia and Other Cattle Ailments in Niger State, Nigeria. ( 26464953 )
2015
50
A large-scale genomic approach affords unprecedented resolution for the molecular epidemiology and evolutionary history of contagious caprine pleuropneumonia. ( 26149260 )
2015

Variations for Pleuropneumonia

Expression for Pleuropneumonia

Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for Pleuropneumonia

Pathways related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.21 CXCL9 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
2
Show member pathways
13.02 CD19 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
3
Show member pathways
12.83 CXCL9 IRAK1 IRAK3 IRAK4 MYD88
4 12.56 IL1R1 IRAK1 IRAK4 MYD88
5
Show member pathways
12.5 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
6
Show member pathways
12.44 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
7 12.35 CD19 IRAK1 IRAK3 IRAK4 MYD88
8
Show member pathways
12.26 IRAK1 IRAK3 IRAK4 MYD88
9
Show member pathways
12.24 IRAK1 IRAK3 IRAK4 MYD88
10 12.13 CD19 IRAK1 IRAK4 MYD88
11
Show member pathways
12.07 IRAK1 IRAK3 IRAK4 MYD88
12
Show member pathways
12.06 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
13 12.03 IRAK1 IRAK4 MYD88
14
Show member pathways
12 IL1R1 IRAK1 IRAK4 MYD88
15
Show member pathways
11.96 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
16
Show member pathways
11.77 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
17 11.6 IL1R1 IRAK1 IRAK4 MYD88
18 11.59 IRAK1 IRAK4 MYD88
19
Show member pathways
11.27 COL18A1 CXCL9 IL1R1 IRAK1 IRAK3 IRAK4
20 10.99 IL1R1 IRAK1 IRAK3 MYD88
21 10.98 IL1R1 IRAK1 MYD88

GO Terms for Pleuropneumonia

Cellular components related to Pleuropneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 9.43 HBB HBD SERPINC1
2 extracellular space GO:0005615 9.23 CELA3B COL18A1 CXCL9 GGT1 HBB IRAK4
3 hemoglobin complex GO:0005833 9.16 HBB HBD
4 haptoglobin-hemoglobin complex GO:0031838 8.96 HBB HBD

Biological processes related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.78 HBB HBD PLAT SERPINC1
2 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.74 IRAK1 IRAK4 MYD88
3 response to lipopolysaccharide GO:0032496 9.73 GGT1 IRAK1 IRAK3 MYD88
4 cytokine-mediated signaling pathway GO:0019221 9.72 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.71 IRAK1 IRAK3 IRAK4 MYD88
6 regulation of inflammatory response GO:0050727 9.7 GGT1 IL1R1 MYD88
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.67 IRAK1 IRAK4 MYD88
8 JNK cascade GO:0007254 9.63 IRAK1 IRAK4 MYD88
9 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.56 CD19 CXCL9
10 hydrogen peroxide catabolic process GO:0042744 9.55 HBB HBD
11 oxygen transport GO:0015671 9.54 HBB HBD
12 toll-like receptor signaling pathway GO:0002224 9.54 IRAK1 IRAK4 MYD88
13 response to peptidoglycan GO:0032494 9.51 IRAK3 MYD88
14 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.46 IRAK1 IRAK3 IRAK4 MYD88
15 toll-like receptor 9 signaling pathway GO:0034162 9.43 IRAK1 IRAK4 MYD88
16 response to interleukin-1 GO:0070555 9.26 IL1R1 IRAK1 IRAK3 MYD88
17 interleukin-1-mediated signaling pathway GO:0070498 9.02 IL1R1 IRAK1 IRAK3 IRAK4 MYD88

Molecular functions related to Pleuropneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peroxidase activity GO:0004601 9.37 HBB HBD
2 interleukin-1 receptor binding GO:0005149 9.32 IRAK4 MYD88
3 oxygen carrier activity GO:0005344 9.26 HBB HBD
4 organic acid binding GO:0043177 9.16 HBB HBD
5 haptoglobin binding GO:0031720 8.96 HBB HBD
6 hemoglobin alpha binding GO:0031721 8.62 HBB HBD

Sources for Pleuropneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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