MCID: PLX001
MIFTS: 35

Plexiform Schwannoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Plexiform Schwannoma

MalaCards integrated aliases for Plexiform Schwannoma:

Name: Plexiform Schwannoma 12 15 73
Plexiform Neurilemmoma 12
Plexiform Neurinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3206
NCIt 50 C6969
SNOMED-CT 68 985004
UMLS 73 C1370659

Summaries for Plexiform Schwannoma

MalaCards based summary : Plexiform Schwannoma, also known as plexiform neurilemmoma, is related to neurofibromatosis, type iv, of riccardi and neurilemmomatosis. An important gene associated with Plexiform Schwannoma is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Neuroscience and B Cell Development Pathways. Affiliated tissues include small intestine, skin and brain, and related phenotypes are behavior/neurological and cellular

Related Diseases for Plexiform Schwannoma

Diseases related to Plexiform Schwannoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 neurofibromatosis, type iv, of riccardi 30.7 KIT NF1 NF2
2 neurilemmomatosis 30.2 NF1 NF2
3 neurilemmoma 29.6 ENO2 GFAP KIT NF1 NF2 NGFR
4 neurofibromatosis, familial spinal 10.2 NF1 NF2
5 immature cataract 10.2 NF1 NF2
6 meningothelial meningioma 10.2 ENO2 NF2
7 neurofibrosarcoma 10.2 NF1 NF2
8 plexiform neurofibroma 10.2 NF1 NF2
9 amyloid tumor 10.2 NF1 NF2
10 duodenal somatostatinoma 10.2 ENO2 NF1
11 epithelioid malignant peripheral nerve sheath tumor 10.2 ENO2 NF1
12 neurofibromatosis, type i 10.2 KIT NF1
13 autonomic nervous system benign neoplasm 10.2 ENO2 NF1
14 dysgerminoma 10.2 ENO2 KIT
15 psammomatous meningioma 10.2 CD34 NF2
16 epithelioid neurofibroma 10.2 CD34 DSP
17 cutaneous ganglioneuroma 10.2 ENO2 KIT
18 perineurioma 10.2 DSP KIT
19 acoustic neuroma 10.2 NF1 NF2
20 gastric leiomyosarcoma 10.2 ENO2 KIT
21 endometrial small cell carcinoma 10.2 ENO2 KIT
22 small cell carcinoma 10.2 ENO2 KIT
23 rete testis adenocarcinoma 10.2 ENO2 KIT
24 epulis 10.1 ENO2 NGFR
25 vulvar melanoma 10.1 KIT NF1
26 mucosal melanoma 10.1 KIT NF1
27 lung meningioma 10.1 CD34 ENO2
28 prostate small cell carcinoma 10.1 ENO2 KIT
29 heart sarcoma 10.1 ENO2 KIT
30 rete testis neoplasm 10.1 ENO2 KIT
31 gallbladder leiomyoma 10.1 CD34 KIT
32 lung leiomyosarcoma 10.1 CD34 KIT
33 neurofibromatosis, type ii 10.1 NF1 NF2
34 liver leiomyoma 10.1 CD34 KIT
35 extracutaneous mastocytoma 10.1 CD34 KIT
36 pineal parenchymal tumor of intermediate differentiation 10.1 ENO2 NF1
37 small intestine leiomyosarcoma 10.1 CD34 KIT
38 small intestinal sarcoma 10.1 CD34 KIT
39 gallbladder sarcoma 10.1 CD34 KIT
40 prostate leiomyosarcoma 10.1 CD34 KIT
41 malignant glandular tumor of peripheral nerve sheath 10.1 B3GAT1 NF1
42 mixed cell type cancer 10.1 ENO2 KIT
43 peritoneal benign neoplasm 10.1 CD34 KIT
44 diffuse peritoneal leiomyomatosis 10.1 CD34 KIT
45 large cell neuroendocrine carcinoma 10.1 ENO2 KIT
46 follicular dendritic cell sarcoma 10.1 DSP KIT
47 breast angiosarcoma 10.1 CD34 KIT
48 senile angioma 10.1 CD34 KIT
49 macrodactyly 10.1
50 spindle cell liposarcoma 10.1 CD34 KIT

Graphical network of the top 20 diseases related to Plexiform Schwannoma:



Diseases related to Plexiform Schwannoma

Symptoms & Phenotypes for Plexiform Schwannoma

MGI Mouse Phenotypes related to Plexiform Schwannoma:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.04 B3GAT1 ENO2 GFAP KIT NF1 NF2
2 cellular MP:0005384 10.02 CD34 DSP ENO2 GFAP KIT NF1
3 growth/size/body region MP:0005378 9.95 DSP ENO2 GFAP KIT NF1 NF2
4 craniofacial MP:0005382 9.93 DSP ENO2 KIT NF1 NF2 NGFR
5 digestive/alimentary MP:0005381 9.83 DSP GFAP KIT NF1 NGFR
6 integument MP:0010771 9.8 CD34 DSP KIT NF1 NF2 NGFR
7 nervous system MP:0003631 9.76 B3GAT1 DSP ENO2 GFAP KIT NF1
8 hearing/vestibular/ear MP:0005377 9.67 KIT NF1 NF2 NGFR
9 muscle MP:0005369 9.65 DSP GFAP KIT NF1 NGFR
10 respiratory system MP:0005388 9.35 ENO2 KIT NF1 NF2 NGFR
11 vision/eye MP:0005391 9.02 GFAP KIT NF1 NF2 NGFR

Drugs & Therapeutics for Plexiform Schwannoma

Search Clinical Trials , NIH Clinical Center for Plexiform Schwannoma

Genetic Tests for Plexiform Schwannoma

Anatomical Context for Plexiform Schwannoma

MalaCards organs/tissues related to Plexiform Schwannoma:

41
Small Intestine, Skin, Brain, Spinal Cord, Prostate, Testis, Pineal

Publications for Plexiform Schwannoma

Articles related to Plexiform Schwannoma:

(show top 50) (show all 70)
# Title Authors Year
1
Magnetic resonance imaging findings for differential diagnosis of perianal plexiform schwannoma: Case report and review of the literature. ( 29774221 )
2018
2
Plexiform Schwannoma with Localized Hypertrichosis. ( 30065605 )
2018
3
Sudden-onset C8 Radiculopathy due to a Plexiform Schwannoma of the Cervical Nerve Root. ( 29984772 )
2018
4
Plexiform Schwannoma of the Tongue in a Pediatric Patient with Neurofibromatosis Type 2: A Case Report and Review of Literature. ( 30410810 )
2018
5
Recurrent plexiform schwannoma involving the carotid canal. ( 28487042 )
2017
6
Plexiform Schwannoma of the Finger: A Case Report and Literature Review. ( 28979871 )
2017
7
Percutaneous Image-Guided Cryotherapy for Local Control of Recurrent Plexiform Schwannoma in a 3-Year-Old Male. ( 28431654 )
2017
8
Gastric plexiform schwannoma in association with neurofibromatosis type 2. ( 27696205 )
2016
9
Congenital cellular plexiform schwannoma mimicking a vascular lesion: Potential pitfalls in clinical and histopathological assessment. ( 26728820 )
2016
10
Plexiform schwannoma: an unusual clitoral mass. ( 27818132 )
2016
11
Plexiform schwannoma of the thoracolumbar spine a rare clinical entity - a case report. ( 27809595 )
2016
12
A rare case of plexiform schwannoma of the lower lip: Treatment and management. ( 26424990 )
2015
13
Plexiform schwannoma of the posterior pharyngeal wall in a patient with neurofibromatosis 2. ( 25738721 )
2015
14
Congenital cellular plexiform schwannoma mimicking a vascular lesion: Potential pitfalls in clinical and histopathological assessment. ( 26658391 )
2015
15
Successful enucleation of large multinodular/plexiform schwannoma of the foot and ankle. ( 26090307 )
2015
16
Plexiform schwannoma involving the trachea and recurrent laryngeal nerve: a case report. ( 26366364 )
2015
17
Oral plexiform schwannoma withA unusual epithelial induction. ( 26268670 )
2015
18
Plexiform Schwannoma of Lumbar Region. ( 26064806 )
2015
19
Plexiform schwannoma arising from cauda equina. ( 25264320 )
2014
20
Multinodular/plexiform schwannoma of the ulnar nerve. ( 24165375 )
2014
21
Plexiform schwannoma of the rectum. ( 23363231 )
2014
22
Case presentations and review of plexiform schwannoma in the foot. ( 24556484 )
2014
23
Plexiform schwannoma of the clitoris in a young girl: a case report. ( 23947092 )
2013
24
Neuroimage: giant plexiform schwannoma of the penis. ( 23207604 )
2013
25
Unusual intramaxillary plexiform schwannoma. ( 22847037 )
2013
26
Macrodactyly in the setting of a plexiform schwannoma in neurofibromatosis type 2: case report. ( 23453897 )
2013
27
Plexiform schwannoma of the duodenum accompanying pyloric stenosis: report of a case. ( 22965512 )
2012
28
A rare case of life-threatening giant plexiform schwannoma. ( 22209242 )
2012
29
Plexiform Schwannoma of the nasal tip: surgical approach. ( 22714859 )
2012
30
Multiple plexiform schwannoma of a finger. ( 22266205 )
2012
31
Plexiform schwannoma of the foot: a review of the literature and case report. ( 20833568 )
2011
32
Giant plexiform schwannoma of the tongue. ( 22937374 )
2011
33
Lobular breast carcinoma metastasis to a superficial plexiform schwannoma as the first evidence of an occult breast cancer. ( 22123192 )
2011
34
A giant plexiform schwannoma of the brachial plexus: case report. ( 22044580 )
2011
35
Laryngeal plexiform schwannoma as first symptom in a patient with neurofibromatosis type 2. ( 20303213 )
2010
36
Intraosseus plexiform schwannoma of the mandible: immunohistochemical differential diagnosis. ( 21119430 )
2010
37
Plexiform schwannoma in schwannomatosis. ( 19884750 )
2009
38
Plexiform schwannoma of the esophagus in a child with neurofibromatosis type 2. ( 19573680 )
2009
39
Plexiform schwannoma of the lip mucosa. ( 19415817 )
2009
40
Plexiform schwannoma of the posterior tibial nerve: a case report. ( 19918424 )
2009
41
Plexiform schwannoma: a clinicopathologic overview with emphasis on the head and neck region. ( 18439936 )
2008
42
Isolated plexiform schwannoma of the hand. ( 21886708 )
2008
43
Cutaneous plexiform schwannoma of the finger not associated with neurofibromatosis. ( 18284268 )
2008
44
Congenital plexiform schwannoma of the clitoris. ( 18382807 )
2008
45
Plexiform schwannoma of scalp: a case report with brief review of literature. ( 18306559 )
2007
46
Intra-extradural plexiform schwannoma of the cervical spine. ( 17906563 )
2007
47
Plexiform schwannoma of the clitoris. ( 17614860 )
2007
48
Plexiform schwannoma mimicking haemangioma: pitfalls in clinical diagnosis and histological interpretation. ( 17714565 )
2007
49
Epithelioid angiosarcoma arising in a deep-seated plexiform schwannoma: a case report and literature review. ( 17574948 )
2007
50
Recurrent plexiform schwannoma in vestibular mucosa. ( 16681871 )
2006

Variations for Plexiform Schwannoma

Expression for Plexiform Schwannoma

Search GEO for disease gene expression data for Plexiform Schwannoma.

Pathways for Plexiform Schwannoma

Pathways related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 ENO2 GFAP NF1 NF2 NGFR
2 10.68 CD34 KIT

GO Terms for Plexiform Schwannoma

Cellular components related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.28 B3GAT1 CD34 DSP ENO2 GFAP KIT

Biological processes related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual learning GO:0008542 9.37 KIT NF1
2 pigmentation GO:0043473 9.32 KIT NF1
3 negative regulation of MAPK cascade GO:0043409 9.26 NF1 NF2
4 negative regulation of cell-matrix adhesion GO:0001953 9.16 NF1 NF2
5 regulation of cell proliferation GO:0042127 9.13 KIT NF1 NF2
6 intermediate filament organization GO:0045109 8.62 DSP GFAP

Sources for Plexiform Schwannoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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