MCID: PLX001
MIFTS: 33

Plexiform Schwannoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Plexiform Schwannoma

MalaCards integrated aliases for Plexiform Schwannoma:

Name: Plexiform Schwannoma 12 15 73
Plexiform Neurilemmoma 12
Plexiform Neurinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3206
NCIt 50 C6969
UMLS 73 C1370659

Summaries for Plexiform Schwannoma

MalaCards based summary : Plexiform Schwannoma, also known as plexiform neurilemmoma, is related to neurofibromatosis, type ii and neurilemmoma. An important gene associated with Plexiform Schwannoma is NF2 (Neurofibromin 2), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include trachea, tongue and breast, and related phenotypes are behavior/neurological and cellular

Related Diseases for Plexiform Schwannoma

Diseases related to Plexiform Schwannoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 neurofibromatosis, type ii 30.3 NF1 NF2
2 neurilemmoma 27.0 ENO2 GFAP KIT NF1 NF2 NGFR
3 neurofibromatosis, familial spinal 10.8 NF1 NF2
4 neurofibrosarcoma 10.7 NF1 NF2
5 immature cataract 10.7 NF1 NF2
6 meningothelial meningioma 10.7 ENO2 NF2
7 plexiform neurofibroma 10.7 NF1 NF2
8 amyloid tumor 10.6 NF1 NF2
9 duodenal somatostatinoma 10.6 ENO2 NF1
10 epithelioid malignant peripheral nerve sheath tumor 10.6 ENO2 NF1
11 neurilemmomatosis 10.6 NF1 NF2
12 epithelioid neurofibroma 10.6 CD34 DSP
13 melanotic neurilemmoma 10.6 CD34 NF2
14 psammomatous meningioma 10.6 CD34 NF2
15 cutaneous ganglioneuroma 10.5 ENO2 KIT
16 endometrial small cell carcinoma 10.5 ENO2 KIT
17 rete testis adenocarcinoma 10.5 ENO2 KIT
18 vulvar melanoma 10.5 KIT NF1
19 mucosal melanoma 10.5 KIT NF1
20 acoustic neuroma 10.4 NF1 NF2
21 heart sarcoma 10.4 ENO2 KIT
22 epulis 10.4 ENO2 NGFR
23 rete testis neoplasm 10.4 ENO2 KIT
24 lymphangiosarcoma 10.4 CD34 DSP
25 neurofibromatosis, type i 10.4 KIT NF1
26 gallbladder leiomyoma 10.4 CD34 KIT
27 lung leiomyosarcoma 10.4 CD34 KIT
28 liver leiomyoma 10.4 CD34 KIT
29 mixed cell type cancer 10.4 ENO2 KIT
30 extracutaneous mastocytoma 10.4 CD34 KIT
31 small intestine leiomyosarcoma 10.4 CD34 KIT
32 small intestinal sarcoma 10.4 CD34 KIT
33 gallbladder sarcoma 10.4 CD34 KIT
34 prostate leiomyosarcoma 10.4 CD34 KIT
35 malignant glandular tumor of peripheral nerve sheath 10.4 B3GAT1 NF1
36 diffuse cutaneous mastocytosis 10.4 CD34 KIT
37 sarcomatoid squamous cell skin carcinoma 10.4 CD34 KIT
38 breast angiosarcoma 10.4 CD34 KIT
39 pleomorphic lipoma 10.3 CD34 NF1
40 senile angioma 10.3 CD34 KIT
41 spindle cell liposarcoma 10.3 CD34 KIT
42 olfactory neuroblastoma 10.3 ENO2 NGFR
43 large cell neuroendocrine carcinoma 10.3 ENO2 KIT
44 kidney rhabdoid cancer 10.3 B3GAT1 ENO2
45 spinal meningioma 10.3 ENO2 NF1 NF2
46 spinal canal and spinal cord meningioma 10.3 ENO2 NF1 NF2
47 optic nerve neoplasm 10.3 ENO2 NF1 NF2
48 mesenchymal cell neoplasm 10.3 CD34 KIT
49 gastric small cell carcinoma 10.3 B3GAT1 ENO2
50 intraneural perineurioma 10.3 CD34 NF1

Graphical network of the top 20 diseases related to Plexiform Schwannoma:



Diseases related to Plexiform Schwannoma

Symptoms & Phenotypes for Plexiform Schwannoma

MGI Mouse Phenotypes related to Plexiform Schwannoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.98 KIT B3GAT1 NF1 NF2 ENO2 NGFR
2 cellular MP:0005384 9.95 KIT CD34 NF1 DSP ENO2 NGFR
3 craniofacial MP:0005382 9.85 NF1 DSP NF2 ENO2 NGFR KIT
4 integument MP:0010771 9.73 NF1 CD34 DSP NF2 NGFR KIT
5 digestive/alimentary MP:0005381 9.72 KIT NF1 DSP GFAP NGFR
6 nervous system MP:0003631 9.56 B3GAT1 NF1 DSP NF2 ENO2 NGFR
7 muscle MP:0005369 9.55 KIT NF1 DSP GFAP NGFR
8 respiratory system MP:0005388 9.02 KIT NF1 NF2 ENO2 NGFR

Drugs & Therapeutics for Plexiform Schwannoma

Search Clinical Trials , NIH Clinical Center for Plexiform Schwannoma

Genetic Tests for Plexiform Schwannoma

Anatomical Context for Plexiform Schwannoma

MalaCards organs/tissues related to Plexiform Schwannoma:

41
Trachea, Tongue, Breast, Small Intestine

Publications for Plexiform Schwannoma

Articles related to Plexiform Schwannoma:

(show top 50) (show all 69)
# Title Authors Year
1
Magnetic resonance imaging findings for differential diagnosis of perianal plexiform schwannoma: Case report and review of the literature. ( 29774221 )
2018
2
Recurrent plexiform schwannoma involving the carotid canal. ( 28487042 )
2017
3
Plexiform Schwannoma of the Finger: A Case Report and Literature Review. ( 28979871 )
2017
4
Percutaneous Image-Guided Cryotherapy for Local Control of Recurrent Plexiform Schwannoma in a 3-Year-Old Male. ( 28431654 )
2017
5
Gastric plexiform schwannoma in association with neurofibromatosis type 2. ( 27696205 )
2016
6
Congenital cellular plexiform schwannoma mimicking a vascular lesion: Potential pitfalls in clinical and histopathological assessment. ( 26728820 )
2016
7
Plexiform schwannoma: an unusual clitoral mass. ( 27818132 )
2016
8
Plexiform schwannoma of the thoracolumbar spine a rare clinical entity - a case report. ( 27809595 )
2016
9
A rare case of plexiform schwannoma of the lower lip: Treatment and management. ( 26424990 )
2015
10
Plexiform schwannoma of the posterior pharyngeal wall in a patient with neurofibromatosis 2. ( 25738721 )
2015
11
Congenital cellular plexiform schwannoma mimicking a vascular lesion: Potential pitfalls in clinical and histopathological assessment. ( 26658391 )
2015
12
Successful enucleation of large multinodular/plexiform schwannoma of the foot and ankle. ( 26090307 )
2015
13
Plexiform schwannoma involving the trachea and recurrent laryngeal nerve: a case report. ( 26366364 )
2015
14
Oral plexiform schwannoma withA unusual epithelial induction. ( 26268670 )
2015
15
Plexiform Schwannoma of Lumbar Region. ( 26064806 )
2015
16
Plexiform schwannoma arising from cauda equina. ( 25264320 )
2014
17
Multinodular/plexiform schwannoma of the ulnar nerve. ( 24165375 )
2014
18
Plexiform schwannoma of the rectum. ( 23363231 )
2014
19
Case presentations and review of plexiform schwannoma in the foot. ( 24556484 )
2014
20
Plexiform schwannoma of the clitoris in a young girl: a case report. ( 23947092 )
2013
21
Neuroimage: giant plexiform schwannoma of the penis. ( 23207604 )
2013
22
Unusual intramaxillary plexiform schwannoma. ( 22847037 )
2013
23
Macrodactyly in the setting of a plexiform schwannoma in neurofibromatosis type 2: case report. ( 23453897 )
2013
24
Plexiform schwannoma of the duodenum accompanying pyloric stenosis: report of a case. ( 22965512 )
2012
25
Multiple cutaneous plexiform schwannomas as initial presentation of neurofibromatosis 2 in a 9-year-old. ( 21906157 )
2012
26
A rare case of life-threatening giant plexiform schwannoma. ( 22209242 )
2012
27
Plexiform Schwannoma of the nasal tip: surgical approach. ( 22714859 )
2012
28
Multiple plexiform schwannoma of a finger. ( 22266205 )
2012
29
Plexiform schwannoma of the foot: a review of the literature and case report. ( 20833568 )
2011
30
Giant plexiform schwannoma of the tongue. ( 22937374 )
2011
31
Lobular breast carcinoma metastasis to a superficial plexiform schwannoma as the first evidence of an occult breast cancer. ( 22123192 )
2011
32
A giant plexiform schwannoma of the brachial plexus: case report. ( 22044580 )
2011
33
Laryngeal plexiform schwannoma as first symptom in a patient with neurofibromatosis type 2. ( 20303213 )
2010
34
Intraosseus plexiform schwannoma of the mandible: immunohistochemical differential diagnosis. ( 21119430 )
2010
35
Plexiform schwannoma in schwannomatosis. ( 19884750 )
2009
36
Plexiform schwannoma of the esophagus in a child with neurofibromatosis type 2. ( 19573680 )
2009
37
Plexiform schwannoma of the lip mucosa. ( 19415817 )
2009
38
Plexiform schwannoma of the posterior tibial nerve: a case report. ( 19918424 )
2009
39
Plexiform schwannoma: a clinicopathologic overview with emphasis on the head and neck region. ( 18439936 )
2008
40
Isolated plexiform schwannoma of the hand. ( 21886708 )
2008
41
Cutaneous plexiform schwannoma of the finger not associated with neurofibromatosis. ( 18284268 )
2008
42
Congenital plexiform schwannoma of the clitoris. ( 18382807 )
2008
43
Plexiform schwannoma of scalp: a case report with brief review of literature. ( 18306559 )
2007
44
Intra-extradural plexiform schwannoma of the cervical spine. ( 17906563 )
2007
45
Plexiform schwannoma of the clitoris. ( 17614860 )
2007
46
Plexiform schwannoma mimicking haemangioma: pitfalls in clinical diagnosis and histological interpretation. ( 17714565 )
2007
47
Epithelioid angiosarcoma arising in a deep-seated plexiform schwannoma: a case report and literature review. ( 17574948 )
2007
48
Contiguous conventional and plexiform schwannomas. Report of two cases. ( 16509508 )
2006
49
Recurrent plexiform schwannoma in vestibular mucosa. ( 16681871 )
2006
50
Plexiform schwannoma of the ulnar nerve. ( 16019742 )
2005

Variations for Plexiform Schwannoma

Expression for Plexiform Schwannoma

Search GEO for disease gene expression data for Plexiform Schwannoma.

Pathways for Plexiform Schwannoma

Pathways related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 ENO2 GFAP NF1 NF2 NGFR

GO Terms for Plexiform Schwannoma

Cellular components related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 desmosome GO:0030057 8.96 CDSN DSP
2 cell-cell junction GO:0005911 8.8 CDSN DSP KIT

Biological processes related to Plexiform Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual learning GO:0008542 9.4 KIT NF1
2 pigmentation GO:0043473 9.37 KIT NF1
3 negative regulation of MAPK cascade GO:0043409 9.32 NF1 NF2
4 negative regulation of cell-matrix adhesion GO:0001953 9.26 NF1 NF2
5 intermediate filament organization GO:0045109 9.16 DSP GFAP
6 cell-cell adhesion GO:0098609 9.13 CD34 CDSN DSP
7 regulation of cell proliferation GO:0042127 8.92 KIT NF1 NF2 NGFR

Sources for Plexiform Schwannoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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