MCID: PLC002
MIFTS: 21

Plica Syndrome

Categories: Bone diseases

Aliases & Classifications for Plica Syndrome

MalaCards integrated aliases for Plica Syndrome:

Name: Plica Syndrome 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:12225
ICD9CM 35 727.83
ICD10 33 M67.5
UMLS 72 C0878705

Summaries for Plica Syndrome

MalaCards based summary : Plica Syndrome is related to synovitis and hemarthrosis. An important gene associated with Plica Syndrome is SHANK2 (SH3 And Multiple Ankyrin Repeat Domains 2), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone and testes.

Wikipedia : 75 Plica syndrome is a condition that occurs when a plica (a vestigial extension of the protective synovial... more...

Related Diseases for Plica Syndrome

Diseases related to Plica Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 synovitis 10.1
2 hemarthrosis 9.9
3 heart valve disease 9.8 VWF ELN
4 myxosarcoma 9.8 VWF CD68
5 varicose veins 9.8 VWF ELN
6 aortic valve disease 2 9.7 VWF ELN
7 aortic valve disease 1 9.6 VWF ELN
8 bone marrow cancer 9.4 VWF CD38

Graphical network of the top 20 diseases related to Plica Syndrome:



Diseases related to Plica Syndrome

Symptoms & Phenotypes for Plica Syndrome

Drugs & Therapeutics for Plica Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Medial Plica Syndrome of the Knee: Conservative Treatment Versus Arthroscopic Plica Resection - a Randomized Controlled Multicenter Trial Recruiting NCT02578589

Search NIH Clinical Center for Plica Syndrome

Genetic Tests for Plica Syndrome

Anatomical Context for Plica Syndrome

MalaCards organs/tissues related to Plica Syndrome:

41
Bone, Testes

Publications for Plica Syndrome

Articles related to Plica Syndrome:

(show top 50) (show all 95)
# Title Authors PMID Year
1
Suprapatellar plica classification and suprapatellar plica syndrome. 38
31044135 2019
2
Arthroscopic treatment of symptomatic lateral synovial plica of the knee. 38
30862262 2019
3
Clinical Management of Medial Patellar Plica Syndrome: Expert Point of View from Diagnosis to Treatment 38
30474533 2018
4
Prominent synovial plicae in radiocapitellar joints as a potential cause of lateral elbow pain: clinico-radiologic correlation. 38
30016689 2018
5
Evaluation and management of knee pain in young athletes: overuse injuries of the knee. 38
28795010 2017
6
Knee Osteoarthritis after Reconstruction of Isolated Anterior Cruciate Ligament Injuries: A Systematic Literature Review. 38
29114629 2017
7
Long term results after arthroscopic resection of medial plicae of the knee-a prospective study. 38
27761630 2017
8
Magnetic resonance imaging of posterolateral plica of the elbow joint: Asymptomatic vs. symptomatic subjects. 38
28622337 2017
9
Synovial Plica Syndrome of the Knee: A Commonly Overlooked Cause of Anterior Knee Pain. 38
28825013 2017
10
MRI of lower extremity impingement and friction syndromes in children. 38
27538047 2016
11
[Long-term outcomes of arthroscopy and non-surgical therapy in patients with knee synovial plica syndrome]. 38
27578592 2016
12
The Role of Complete Suprapatellar Plicae. 38
27274453 2016
13
Characteristics of medial plica syndrome complicated with cartilage damage. 38
25900367 2015
14
A rare cause of posterolateral elbow pain: radio- humeral plica syndrome with typical MRI findings. 38
25786299 2014
15
US for diagnosis of musculoskeletal conditions in the young athlete: emphasis on dynamic assessment. 38
25208273 2014
16
[Chronic knee pain in children and adolescents: review of anatomical and overload-related knee pain]. 38
25116244 2014
17
MRI of anterior knee pain. 38
24473994 2014
18
Diagnostic test accuracy of clinical and radiological assessments for medial patella plica syndrome: a systematic review and meta-analysis. 38
24280039 2014
19
'The Sneaky Plica' revisited: morphology, pathophysiology and treatment of synovial plicae of the knee. 38
23381917 2014
20
Diagnostic Differences for Anterior Knee Pain between Sexes in Adolescent Basketball Players. 38
25362859 2014
21
Usefulness of knee arthroscopy for diagnosis of knee pain in pediatric patients: comparison with preoperative clinical diagnosis. 38
23508515 2013
22
Elbow plica syndrome: presenting with elbow locking in a pediatric patient. 38
22573209 2012
23
Medial plica syndrome: a review of the literature. 38
22331585 2012
24
Medial plica syndrome of left knee. 38
22880525 2012
25
Lateral epicondylitis and beyond: imaging of lateral elbow pain with clinical-radiologic correlation. 38
22205505 2012
26
Review article: Plica syndrome of the knee. 38
22184170 2011
27
Selected cases of arthroscopic treatment of popliteal cyst with associated intra-articular knee disorders primary report. 38
22248462 2011
28
[Infrapatellar fat pad: anterior crossroads of the knee]. 38
20814373 2010
29
Autologous chondrocyte implantation versus ACI using 3D-bioresorbable graft for the treatment of large full-thickness cartilage lesions of the knee. 38
19711090 2010
30
[Arthroscopy of the elbow]. 38
20857810 2010
31
Diagnosis of medial plica syndrome of the knee with dynamic sonography. 38
20445372 2010
32
Ligamentization of tendon grafts treated with an endogenous preparation rich in growth factors: gross morphology and histology. 38
20362825 2010
33
Synovial plicae around the knee. 38
19781946 2010
34
Arthroscopic treatment of medial shelf syndrome. 38
20206050 2010
35
Gouty tophi presenting as medial patellar plica syndrome and patellofemoral disorder to limit knee range of motion. 38
20197572 2010
36
Overuse injuries of the knee. 38
19887299 2009
37
Medial plica syndrome of the knee: diagnosis with dynamic sonography. 38
19276324 2009
38
Medial plica syndrome. 38
19344015 2009
39
Results of resection of medial patellar plica through a supero-lateral portal as a main arthroscopic procedure. 38
19026191 2008
40
The synovitis of "non-inflammatory" orthopaedic arthropathies: a quantitative histological and immunohistochemical analysis. 38
18203762 2008
41
The medial plica syndrome can mimic recurring acute haemarthroses. 38
18355263 2008
42
Clinical diagnosis of medial plica syndrome of the knee: a prospective study. 38
17993067 2007
43
Arthroscopy of the knee in pre-adolescent children. 38
16830144 2007
44
Retinacular band excision improves outcome in treatment of plica syndrome. 38
16094538 2005
45
Medial synovial plica. 38
17611459 2005
46
MPP test in the diagnosis of medial patellar plica syndrome. 38
15592243 2004
47
MRI of Hoffa's fat pad. 38
15221217 2004
48
Evaluation of patients presenting with knee pain: Part II. Differential diagnosis. 38
13678140 2003
49
Arthroscopic treatment of a symptomatic hip plica. 38
12782873 2003
50
Medial synovial plica syndrome of the knee: a diagnostic pitfall in adolescent athletes. 38
12488771 2003

Variations for Plica Syndrome

Expression for Plica Syndrome

Search GEO for disease gene expression data for Plica Syndrome.

Pathways for Plica Syndrome

Pathways related to Plica Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.69 CD68 CD38

GO Terms for Plica Syndrome

Biological processes related to Plica Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 8.96 VWF ELN
2 long-term synaptic depression GO:0060292 8.62 SHANK2 CD38

Molecular functions related to Plica Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.62 VWF ELN

Sources for Plica Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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