MCID: PLM049
MIFTS: 30

Plummer Vinson Syndrome

Categories: Blood diseases, Gastrointestinal diseases, Immune diseases, Rare diseases
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Aliases & Classifications for Plummer Vinson Syndrome

MalaCards integrated aliases for Plummer Vinson Syndrome:

Name: Plummer Vinson Syndrome 19
Plummer-Vinson Syndrome 19 58 75 71
Sideropenic Dysphagia 19 58 31
Kelly-Paterson Syndrome 19 58
Paterson-Brown-Kelly Syndrome 19
Paterson-Kelly Syndrome 19
Dysphagia Sideropenica 19
Paterson's Syndrome 19
Kelly's Syndrome 19

Characteristics:


Prevelance:

Plummer-Vinson Syndrome: <1/1000000 (Worldwide) 58

Age Of Onset:

Plummer-Vinson Syndrome: Adult 58

Classifications:

Orphanet: 58  
Rare gastroenterological diseases
Rare haematological diseases


External Ids:

ICD10 31 D50.1
MESH via Orphanet 44 D011004
ICD10 via Orphanet 32 D50.1
UMLS via Orphanet 72 C0032249
Orphanet 58 ORPHA54028
UMLS 71 C0032249

Summaries for Plummer Vinson Syndrome

GARD: 19 Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs.

MalaCards based summary: Plummer Vinson Syndrome, also known as plummer-vinson syndrome, is related to jawad syndrome and patterson pseudoleprechaunism syndrome. Affiliated tissues include tongue, hypothalamus and pancreas, and related phenotypes are dysphagia and iron deficiency anemia

Orphanet: 58 Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs.

Wikipedia: 75 Plummer-Vinson syndrome is a rare disease characterized by difficulty swallowing, iron-deficiency... more...

Related Diseases for Plummer Vinson Syndrome

Diseases related to Plummer Vinson Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 jawad syndrome 11.4
2 patterson pseudoleprechaunism syndrome 11.4
3 iron metabolism disease 11.0
4 deficiency anemia 11.0
5 iron deficiency anemia 11.0
6 glossitis 10.7
7 esophageal cancer 10.6
8 celiac disease 1 10.6
9 anemia, sideroblastic, 1 10.6
10 angular cheilitis 10.6
11 cheilitis 10.6
12 candidiasis 10.4
13 sjogren syndrome 10.4
14 atrophic glossitis 10.4
15 esophagus squamous cell carcinoma 10.4
16 squamous cell carcinoma 10.3
17 myeloproliferative neoplasm 10.3
18 gastritis 10.3
19 nutritional deficiency disease 10.3
20 esophageal disease 10.3
21 hypopharynx cancer 10.3
22 crohn's disease 10.3
23 dyskinesia of esophagus 10.3
24 stomatitis 10.3
25 goiter 10.3
26 nodular goiter 10.3
27 alcohol dependence 10.2
28 alcoholic liver cirrhosis 10.2
29 gastroesophageal reflux 10.2
30 coloboma of optic nerve 10.2
31 diaphragmatic hernia, congenital 10.2
32 macroglossia 10.2
33 pernicious anemia 10.2
34 factor vii deficiency 10.2
35 neurofibromatosis-noonan syndrome 10.2
36 allergic rhinitis 10.2
37 gastric cancer 10.2
38 barrett esophagus 10.2
39 riboflavin deficiency 10.2
40 mild cognitive impairment 10.2
41 gastric ulcer 10.2
42 exotropia 10.2
43 esophagitis 10.2
44 pica disease 10.2
45 enterocele 10.2
46 thrombocytosis 10.2
47 colon adenocarcinoma 10.2
48 myoma 10.2
49 adenocarcinoma 10.2
50 anus disease 10.2

Graphical network of the top 20 diseases related to Plummer Vinson Syndrome:



Diseases related to Plummer Vinson Syndrome

Symptoms & Phenotypes for Plummer Vinson Syndrome

Human phenotypes related to Plummer Vinson Syndrome:

58 30 (show all 17)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 dysphagia 58 30 Obligate (100%) Obligate (100%)
HP:0002015
2 iron deficiency anemia 58 30 Obligate (100%) Obligate (100%)
HP:0001891
3 hypochromic microcytic anemia 58 30 Obligate (100%) Obligate (100%)
HP:0004840
4 esophageal web 58 30 Obligate (100%) Obligate (100%)
HP:0100594
5 decreased circulating ferritin concentration 30 Obligate (100%) HP:0012343
6 pallor 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0000980
7 easy fatigability 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0003388
8 glossitis 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0000206
9 abdominal pain 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0002027
10 narrow mouth 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000160
11 cheilitis 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0100825
12 poor appetite 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0004396
13 concave nail 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0001598
14 intra-oral hyperpigmentation 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0010284
15 tongue atrophy 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0012473
16 geophagia 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0025062
17 decreased serum ferritin 58 Obligate (100%)

Drugs & Therapeutics for Plummer Vinson Syndrome

Search Clinical Trials, NIH Clinical Center for Plummer Vinson Syndrome

Genetic Tests for Plummer Vinson Syndrome

Anatomical Context for Plummer Vinson Syndrome

Organs/tissues related to Plummer Vinson Syndrome:

MalaCards : Tongue, Hypothalamus, Pancreas, Colon, Heart

Publications for Plummer Vinson Syndrome

Articles related to Plummer Vinson Syndrome:

(show top 50) (show all 310)
# Title Authors PMID Year
1
Esophageal squamous cell cancer in Plummer-Vinson syndrome: Is lichen planus a missing link? 62
35417996 2022
2
Plummer-Vinson syndrome in primary Sjögren syndrome: a case-based review. 62
34651287 2022
3
The Missing Link: A Case of Plummer-Vinson Syndrome in a Young Pacific-Islander Woman With Helicobacter Pylori. 62
34812318 2021
4
Adam Brown Kelly and his operating chair. 62
34344497 2021
5
Plummer-Vinson Syndrome in an African-American Woman. 62
34616256 2021
6
Plummer-Vinson Syndrome: A Rare Cause of Dysphagia in an Octogenarian. 62
33895769 2021
7
Plummer-Vinson syndrome: A decade's experience of 132 cases from a single center. 62
32525241 2021
8
Paterson-Brown Kelly Syndrome (also commonly known as Plummer-Vinson Syndrome). 62
33235791 2020
9
A Holistic Approach to Diagnosing and Treating Dysphagia. 62
32026277 2020
10
Plummer-Vinson Syndrome in a Crohn's disease patient. 62
32088165 2020
11
Iron Deficiency as Cause of Dysphagia and Burning Mouth (Plummer-Vinson or Kelly-Patterson Syndrome): a Case Report. 62
33002400 2020
12
Idiopathic Cervical Esophageal Webs: A Case Report and Literature Review. 62
33235485 2020
13
A Rare Case of Plummer-Vinson Syndrome. 62
32025392 2019
14
[A rare cause of dysphagia: Plummer Vinson syndrome associated with arteria lusoria]. 62
31703955 2019
15
Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman. 62
31451679 2019
16
Plummer-Vinson Syndrome. 62
31208220 2019
17
[Dysphagia and Anemia. Plummer-Vinson syndrome]. 62
29773525 2019
18
Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained. 62
30449792 2019
19
Plummer-Vinson Syndrome With Concomitant Factor VII Deficiency. 62
31528144 2019
20
Plummer-Vinson syndrome: improving outcomes with a multidisciplinary approach. 62
31417270 2019
21
Paterson-Brown-Kelly syndrome. 62
29884482 2018
22
Colon Adenocarcinoma Presenting as Plummer-Vinson Syndrome. 62
29885869 2018
23
[Kelly-Paterson Syndrome and coeliac disease in adult]. 62
30292384 2018
24
A Web Effect: Plummer-Vinson Syndrome. 62
29374547 2018
25
An unusual etiology of plummer-Vinson syndrome. 62
29662867 2018
26
Plummer Vinson syndrome. 62
28223067 2018
27
Image Diagnosis: Plummer-Vinson Syndrome: An Unusual Cause of Dysphagia. 62
30005727 2018
28
Plummer-Vinson Syndrome with Simultaneous Mid-esophageal Growth. 62
28457047 2017
29
Iron deficiency anemia and Plummer-Vinson syndrome: current insights. 62
29089792 2017
30
Plummer Vinson Syndrome: A Rare Syndrome in Male with Review of the Literature. 62
28932606 2017
31
Estimation of hemoglobin, serum iron, total iron-binding capacity and serum ferritin levels in oral submucous fibrosis: A clinicopathological study. 62
28479683 2017
32
Long-term evolution of squamous-cell cancer in Plummer-Vinson syndrome. 62
29123586 2017
33
Koilonychia: an update on pathophysiology, differential diagnosis and clinical relevance. 62
27531645 2016
34
Electroincision for hypopharyngoesophageal stricture caused by Plummer-Vinson syndrome. 62
27311656 2016
35
Single-center prospective study of Plummer-Vinson syndrome. 62
26227908 2016
36
Plummer-Vinson Syndrome with Proximal Esophageal Web. 62
26658794 2016
37
Plummer-Vinson Syndrome. 62
26944249 2016
38
Resolution of constipation, anal stricture, and iron deficiency anemia after iron infusion: an analogy with Plummer Vinson syndrome. 62
27917348 2016
39
Two cases with Plummer-Vinson syndrome in the 21st century. 62
26620961 2016
40
Spooning of the nails and webbing of the esophagus: koilonychia and Plummer-Vinson Syndrome. 62
26734146 2015
41
Plummer-Vinson Syndrome in Children. 62
26502163 2015
42
PLUMMER VINSON SYNDROME--is it common in males? 62
26486296 2015
43
Oral manifestations of plummer-vinson syndrome: a classic report with literature review. 62
25878483 2015
44
Iron Supplementation Improved Dysphagia Related to Plummer-Vinson Syndrome. 62
26411779 2015
45
Plummer-Vinson syndrome following gastric bypass surgery. 62
25255352 2014
46
A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy. 62
25028578 2014
47
A case of plummer-vinson syndrome associated with Crohn's disease. 62
24755750 2014
48
Plummer-Vinson syndrome with pectus carinatum mitral valve prolapsus and exotropia in an 18-year-old boy. 62
24451233 2014
49
[Unusual presentations of Plummer-Vinson syndrome in Black African: report of two cases]. 62
25767665 2014
50
Plummer-Vinson syndrome. 62
23707464 2013

Variations for Plummer Vinson Syndrome

Expression for Plummer Vinson Syndrome

Search GEO for disease gene expression data for Plummer Vinson Syndrome.

Pathways for Plummer Vinson Syndrome

GO Terms for Plummer Vinson Syndrome

Sources for Plummer Vinson Syndrome

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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