MCID: PNM003
MIFTS: 34

Pneumatosis Cystoides Intestinalis

Categories: Gastrointestinal diseases

Aliases & Classifications for Pneumatosis Cystoides Intestinalis

MalaCards integrated aliases for Pneumatosis Cystoides Intestinalis:

Name: Pneumatosis Cystoides Intestinalis 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13249
MeSH 45 D011006
SNOMED-CT 69 17465007
UMLS 74 C0032266

Summaries for Pneumatosis Cystoides Intestinalis

MalaCards based summary : Pneumatosis Cystoides Intestinalis is related to scleroderma, familial progressive and intussusception. An important gene associated with Pneumatosis Cystoides Intestinalis is SI (Sucrase-Isomaltase), and among its related pathways/superpathways is Digestion of dietary carbohydrate. Affiliated tissues include colon, bone and small intestine, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Related Diseases for Pneumatosis Cystoides Intestinalis

Diseases related to Pneumatosis Cystoides Intestinalis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 scleroderma, familial progressive 10.7
2 intussusception 10.6
3 dermatomyositis 10.6
4 systemic lupus erythematosus 10.5
5 lupus erythematosus 10.5
6 leukemia 10.5
7 intestinal pseudo-obstruction 10.5
8 connective tissue disease 10.5
9 intestinal volvulus 10.5
10 celiac disease 1 10.4
11 meconium ileus 10.4
12 systemic scleroderma 10.4
13 lymphocytic leukemia 10.4
14 pyloric stenosis 10.4
15 adult dermatomyositis 10.4
16 mixed connective tissue disease 10.4
17 fungal esophagitis 10.4 ATP12A ATP4A
18 diclofenac allergy 10.4 ATP12A ATP4A
19 gastroduodenal crohn's disease 10.4 ATP12A ATP4A
20 neonatal candidiasis 10.4 ATP12A ATP4A
21 photoallergic dermatitis 10.4 ATP12A ATP4A
22 squamous papillomatosis 10.3 ATP12A ATP4A
23 toxic megacolon 10.3 ATP12A ATP4A
24 aspiration pneumonitis 10.3 ATP12A ATP4A
25 gastrointestinal neuroendocrine benign tumor 10.3 ATP12A ATP4A
26 gastric antral vascular ectasia 10.3 ATP12A ATP4A
27 esophageal candidiasis 10.3 ATP12A ATP4A
28 gastric neuroendocrine neoplasm 10.3 ATP12A ATP4A
29 acute laryngitis 10.3 ATP12A ATP4A
30 laryngitis 10.3 ATP12A ATP4A
31 duodenitis 10.3 ATP12A ATP4A
32 rumination disorder 10.3 ATP12A ATP4A
33 active peptic ulcer disease 10.3 ATP12A ATP4A
34 congenital disorder of deglycosylation 10.3 ATP12A ATP4A
35 bladder calculus 10.3 ATP12A ATP4A
36 ischemic neuropathy 10.3 ATP12A ATP4A
37 bile reflux 10.3 ATP12A ATP4A
38 leukemia, acute lymphoblastic 10.3
39 crohn's disease 10.3
40 inflammatory bowel disease 10.3
41 lymphangioma 10.3
42 duodenal ulcer 10.3
43 peritonitis 10.3
44 intestinal obstruction 10.3
45 polymyositis 10.3
46 capillary disease 10.3 ATP12A ATP4A
47 peptic esophagitis 10.3 ATP12A ATP4A
48 hernia, hiatus 10.3 ATP12A ATP4A
49 anismus 10.3 ATP12A ATP4A
50 postsurgical hypothyroidism 10.3 ATP12A ATP4A

Graphical network of the top 20 diseases related to Pneumatosis Cystoides Intestinalis:



Diseases related to Pneumatosis Cystoides Intestinalis

Symptoms & Phenotypes for Pneumatosis Cystoides Intestinalis

MGI Mouse Phenotypes related to Pneumatosis Cystoides Intestinalis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.43 ACE2 ATP12A ATP4A MAN2C1 PDPN PECAM1
2 homeostasis/metabolism MP:0005376 9.32 ACE2 ATP12A ATP4A GLP1R MAN2C1 MGAM

Drugs & Therapeutics for Pneumatosis Cystoides Intestinalis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ultrafast MRI Imaging to Exclude Constipation Completed NCT02658201 Not Applicable

Search NIH Clinical Center for Pneumatosis Cystoides Intestinalis

Cochrane evidence based reviews: pneumatosis cystoides intestinalis

Genetic Tests for Pneumatosis Cystoides Intestinalis

Anatomical Context for Pneumatosis Cystoides Intestinalis

MalaCards organs/tissues related to Pneumatosis Cystoides Intestinalis:

42
Colon, Bone, Small Intestine, Bone Marrow, Skin, Ovary, B Cells

Publications for Pneumatosis Cystoides Intestinalis

Articles related to Pneumatosis Cystoides Intestinalis:

(show top 50) (show all 364)
# Title Authors Year
1
Chronic intestinal pseudo-obstruction with pneumatosis cystoides intestinalis in a patient with systemic sclerosis: A case report. ( 31045831 )
2019
2
Secondary pneumatosis cystoides intestinalis complicated by intestinal volvulus: A case report and literature review. ( 30661712 )
2019
3
Endoscopic Fine-Needle Aspiration Is Useful for the Treatment of Pneumatosis Cystoides Intestinalis With Intussusception. ( 30633030 )
2019
4
Is pneumatosis cystoides intestinalis a lymphatic pathology?: A case of small bowel lymphangioma and subsequent development of pneumatosis cystoides intestinalis in a 57-year-old female. ( 30697407 )
2019
5
Pneumatosis Cystoides Intestinalis with Pneumoperitoneum. ( 30917262 )
2019
6
Pneumatosis Cystoides Intestinalis Secondary to Use of an α-Glucosidase Inhibitor. ( 30644816 )
2019
7
Pneumatosis cystoides intestinalis: A rare benign cause of chronic pain and bloating with pneumoperitoneum. ( 30638604 )
2019
8
Pneumatosis cystoides intestinalis: Not uncommon cause of free air in acute abdomen. ( 30249430 )
2019
9
Pneumatosis Cystoides Intestinalis. ( 29778913 )
2019
10
Pneumatosis Cystoides Intestinalis. ( 29176475 )
2019
11
Pneumatosis Cystoides Intestinalis Secondary to Sunitinib Treatment for Gastrointestinal Stromal Tumor. ( 30186096 )
2018
12
Pneumatosis cystoides intestinalis: a benign differential diagnosis for computed tomographic evidence of pneumoperitoneum in a stable patient. ( 26510647 )
2018
13
Pneumatosis cystoides intestinalis (PCI) in a patient with undiagnosed systemic sclerosis. ( 30269087 )
2018
14
Pneumatosis cystoides intestinalis: six case reports and a review of the literature. ( 29954324 )
2018
15
Focal Pneumatosis cystoides intestinalis: optic colonoscopy and virtual colonoscopy features. ( 29722268 )
2018
16
Prolonged postoperative ileus in a patient with primary pneumatosis cystoides intestinalis: a case report. ( 29542027 )
2018
17
Stenotic Ischemic Enteritis with Concomitant Hepatic Portal Venous Gas and Pneumatosis Cystoides Intestinalis. ( 29491303 )
2018
18
Surgical treatment of pneumatosis cystoides intestinalis with pneumoperitoneum secondary. ( 29391321 )
2018
19
Pneumatosis cystoides intestinalis. ( 29269172 )
2018
20
Pneumatosis cystoides intestinalis in a patient with ulcerative colitis. ( 29253045 )
2017
21
Successful treatment with hyperbaric oxygen therapy for pneumatosis cystoides intestinalis as a complication of granulomatosis with polyangiitis: a case report. ( 28917259 )
2017
22
Successful treatment of prokinetic-resistant intestinal pseudo-obstruction and pneumatosis cystoides intestinalis in systemic sclerosis with metronidazole. ( 28213637 )
2017
23
Midgut volvulus as initial presentation of pneumatosis cystoides intestinalis. ( 25764395 )
2017
24
Pneumatosis cystoides intestinalis. ( 28100056 )
2017
25
Pneumatosis cystoides intestinalis presenting as pneumoperitoneum in a patient with chronic obstructive pulmonary disease: a case report. ( 28241852 )
2017
26
Four Cases of Pneumatosis Cystoides Intestinalis Complicated by Connective Tissue Diseases. ( 28458320 )
2017
27
Reversible pneumatosis cystoides intestinalis after liver transplantation. ( 29280704 )
2017
28
Pneumatosis Cystoides Intestinalis: An Unexpected Cause of Duodenal Nodules. ( 29279079 )
2017
29
A case of pneumatosis cystoides intestinalis. ( 29264102 )
2017
30
Pneumatosis cystoides intestinalis: A rare cause of intraabdominal free air. ( 29260144 )
2017
31
Endoscopic ultrasound to diagnose pneumatosis cystoides intestinalis (with video). ( 29251277 )
2017
32
Pneumatosis Cystoides Intestinalis. ( 29211667 )
2017
33
Pneumatosis cystoides intestinalis: lung window setting on CT. ( 29152295 )
2017
34
Pneumatosis cystoides intestinalis associated with sunitinib and a literature review. ( 29121860 )
2017
35
Pneumatosis Cystoides Intestinalis. ( 28764267 )
2017
36
Two Cases of Pneumatosis Cystoides Intestinalis With Intraperitoneal Free Air. ( 28725312 )
2017
37
Acute pneumatosis cystoides intestinalis with atrophic desmosis of the colon in a child. ( 28630222 )
2017
38
A Case of Intussusception Associated with Pneumatosis Cystoides Intestinalis. ( 27721738 )
2016
39
Lurking in the Wall: Pneumatosis Cystoides Intestinalis with Scleroderma. ( 26724259 )
2016
40
Improvements in Pneumatosis Cystoides Intestinalis and Hepatic Portal Venous Gas with Conservative Therapy in a Patient on Maintenance Dialysis. ( 27374673 )
2016
41
Pneumatosis Cystoides Intestinalis in Patients with Systemic Sclerosis: A Case Report and Review of 39 Japanese Cases. ( 27651961 )
2016
42
Pneumatosis cystoides intestinalis: an unusual cause of intestinal ischemia and pneumoperitoneum. ( 25692421 )
2015
43
Pneumatosis cystoides intestinalis after cetuximab chemotherapy for squamous cell carcinoma of parotid gland. ( 25802792 )
2015
44
Pneumatosis cystoides intestinalis: Is surgery always indicated? ( 25932738 )
2015
45
Endoscopic ultrasound of pneumatosis cystoides intestinalis. ( 26099089 )
2015
46
A Rare Case of Hypermobile Mesentery With Segmental Small Bowel Pneumatosis Cystoides Intestinalis. ( 26576141 )
2015
47
Pneumoperitoneum in a non-acute abdomen-pneumatosis cystoides intestinalis. ( 26943409 )
2015
48
Jejunal overexpression of peptide YY in celiac disease complicated with pneumatosis cystoides intestinalis. ( 25291987 )
2015
49
[Clinical characteristics of patients with pneumatosis cystoides intestinalis]. ( 25759223 )
2015
50
[Epidemiological characteristic of occupational pneumatosis cystoides intestinalis]. ( 25740423 )
2015

Variations for Pneumatosis Cystoides Intestinalis

Expression for Pneumatosis Cystoides Intestinalis

Search GEO for disease gene expression data for Pneumatosis Cystoides Intestinalis.

Pathways for Pneumatosis Cystoides Intestinalis

Pathways related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.58 MGAM SI

GO Terms for Pneumatosis Cystoides Intestinalis

Cellular components related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 8.8 ACE2 PDPN PECAM1

Biological processes related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate metabolic process GO:0005975 9.63 MAN2C1 MGAM SI
2 metabolic process GO:0008152 9.58 MAN2C1 MGAM SI
3 potassium ion import across plasma membrane GO:1990573 9.43 ATP12A ATP4A
4 ATP hydrolysis coupled proton transport GO:0015991 9.37 ATP12A ATP4A
5 cellular sodium ion homeostasis GO:0006883 9.32 ATP12A ATP4A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP12A ATP4A
7 cellular potassium ion homeostasis GO:0030007 9.16 ATP12A ATP4A
8 sodium ion export across plasma membrane GO:0036376 8.96 ATP12A ATP4A
9 polysaccharide digestion GO:0044245 8.62 MGAM SI

Molecular functions related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.85 ACE2 ATP12A ATP4A MAN2C1 MGAM SI
2 carbohydrate binding GO:0030246 9.58 MAN2C1 MGAM SI
3 hydrolase activity, acting on glycosyl bonds GO:0016798 9.33 MAN2C1 MGAM SI
4 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 9.32 MGAM SI
5 sodium:potassium-exchanging ATPase activity GO:0005391 9.26 ATP12A ATP4A
6 alpha-1,4-glucosidase activity GO:0004558 8.65 MGAM
7 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Pneumatosis Cystoides Intestinalis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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