MCID: PNM003
MIFTS: 32

Pneumatosis Cystoides Intestinalis

Categories: Gastrointestinal diseases

Aliases & Classifications for Pneumatosis Cystoides Intestinalis

MalaCards integrated aliases for Pneumatosis Cystoides Intestinalis:

Name: Pneumatosis Cystoides Intestinalis 12 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:13249
MeSH 44 D011006
SNOMED-CT 67 17465007
UMLS 70 C0032266

Summaries for Pneumatosis Cystoides Intestinalis

MalaCards based summary : Pneumatosis Cystoides Intestinalis is related to diarrhea and intestinal perforation. An important gene associated with Pneumatosis Cystoides Intestinalis is SI (Sucrase-Isomaltase), and among its related pathways/superpathways are Carbohydrate digestion and absorption and Digestion of dietary carbohydrate. The drugs Cinnamon and Ginger have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and lung.

Related Diseases for Pneumatosis Cystoides Intestinalis

Diseases related to Pneumatosis Cystoides Intestinalis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 266)
# Related Disease Score Top Affiliating Genes
1 diarrhea 30.7 SI MLN MGAM
2 intestinal perforation 30.7 ATP4A ATP12A
3 diabetic autonomic neuropathy 30.7 SI MLN
4 peptic ulcer disease 30.6 ATP4A ATP12A
5 volvulus of midgut 30.5 MLN ATP4A ATP12A
6 constipation 30.5 MLN ATP4A ATP12A
7 intestinal obstruction 30.4 MLN ATP4A ATP12A
8 exanthem 30.1 ATP4A ATP12A
9 paralytic ileus 30.1 MLN ATP4A ATP12A
10 peptic ulcer perforation 30.1 ATP4A ATP12A
11 gastric dilatation 30.0 ATP4A ATP12A
12 duodenal obstruction 30.0 ATP4A ATP12A
13 aspiration pneumonitis 30.0 ATP4A ATP12A
14 diverticulitis 29.9 ATP4A ATP12A
15 scleroderma, familial progressive 10.9
16 systemic scleroderma 10.7
17 connective tissue disease 10.7
18 peritonitis 10.7
19 dermatomyositis 10.7
20 mixed connective tissue disease 10.6
21 ileus 10.6
22 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.6
23 intestinal pseudo-obstruction 10.6
24 pyloric stenosis 10.6
25 intussusception 10.6
26 systemic lupus erythematosus 10.6
27 duodenal ulcer 10.6
28 lupus erythematosus 10.6
29 graft-versus-host disease 10.5
30 polymyositis 10.5
31 collagen disease 10.5
32 leukemia, acute lymphoblastic 10.5
33 celiac disease 1 10.4
34 enterocolitis 10.4
35 inflammatory bowel disease 10.4
36 gastric ulcer 10.4
37 adult dermatomyositis 10.4
38 lymphangioma 10.4
39 vascular disease 10.4
40 liver cirrhosis 10.4
41 ulcerative colitis 10.4
42 vasculitis 10.4
43 crohn's disease 10.4
44 rare lymphatic malformation 10.4
45 renal cell carcinoma, nonpapillary 10.3
46 pemphigus vulgaris, familial 10.3
47 prostate cancer 10.3
48 down syndrome 10.3
49 duodenal atresia 10.3
50 granulomatosis with polyangiitis 10.3

Graphical network of the top 20 diseases related to Pneumatosis Cystoides Intestinalis:



Diseases related to Pneumatosis Cystoides Intestinalis

Symptoms & Phenotypes for Pneumatosis Cystoides Intestinalis

Drugs & Therapeutics for Pneumatosis Cystoides Intestinalis

Drugs for Pneumatosis Cystoides Intestinalis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cinnamon Approved
2 Ginger Approved
3
Licorice Approved
4 Chinese Rhubarb

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Beneficial Effect of the Traditional Japanese Medicine, Keishi-ka-shakuyaku-daio-to(TJ-134)for Patients With Symptomatic Pneumatosis Cystoides Recruiting NCT04368663 Japanese traditional medicine group

Search NIH Clinical Center for Pneumatosis Cystoides Intestinalis

Cochrane evidence based reviews: pneumatosis cystoides intestinalis

Genetic Tests for Pneumatosis Cystoides Intestinalis

Anatomical Context for Pneumatosis Cystoides Intestinalis

MalaCards organs/tissues related to Pneumatosis Cystoides Intestinalis:

40
Colon, Small Intestine, Lung, Bone Marrow, Prostate, Bone, Brain

Publications for Pneumatosis Cystoides Intestinalis

Articles related to Pneumatosis Cystoides Intestinalis:

(show top 50) (show all 682)
# Title Authors PMID Year
1
Pneumatosis cystoides intestinalis with pneumoperitoneum secondary to stenosing pyloro-duodenal peptic ulcer: Case series of three patients and literature review. 61
33743257 2021
2
A rare cause of lower gastrointestinal bleeding: Pneumatosis cystoides intestinalis. 61
33647344 2021
3
Pneumatosis Cystoides Intestinalis in the Setting of Clindamycin Use: An Association or a Coincidence? 61
32618177 2021
4
The Role of Hyperbaric Oxygen Therapy in Pneumatosis Cystoides Intestinalis-A Scoping Review. 61
33681242 2021
5
Pneumatosis cystoides intestinalis lesions changing into yellowish plaque-like elastosis lesions during healing. 61
32410155 2020
6
[Diagnosis and treatment of pneumatosis cystoides intestinalis]. 61
33212565 2020
7
Case of pneumatosis cystoides intestinalis with pemphigus vulgaris. 61
32789913 2020
8
Pneumatosis cystoides intestinalis: a rare cause of acute abdomen. 61
32954782 2020
9
Chronic Spontaneous Pneumoperitoneum with Pneumatosis Cystoides Intestinalis of the Small and Large Intestine. 61
33717521 2020
10
Pneumatosis cystoides intestinalis. 61
32879604 2020
11
Pneumatosis cystoides intestinalis accompanied by intestinal spirochetosis. 61
31898208 2020
12
Pneumatosis Cystoides Intestinalis Identified on Screening Colonoscopy With Associated Pneumoperitoneum. 61
32884868 2020
13
A case of pneumatosis cystoides intestinalis complicated by intussusception. 61
32671921 2020
14
Pneumatosis cystoides intestinalis diagnosed by underwater biopsy. 61
32273173 2020
15
Non-Occlusive Mesenteric Ischemia Due to Hirudotherapy: A Case Report. 61
32874797 2020
16
Correction to: Pneumatosis cystoides intestinalis induced by the alpha-glucosidase inhibitor complicated from sigmoid volvulus in a diabetic patient. 61
32232554 2020
17
Pneumatosis cystoides intestinalis induced by the alpha-glucosidase inhibitor complicated from sigmoid volvulus in a diabetic patient. 61
32095873 2020
18
Pneumatosis cystoides intestinalis and hyperganglionosis - Cause or effect? A review. 61
32089409 2020
19
Idiopathic Pneumatosis of Small Bowel and Bladder. 61
32607296 2020
20
Pneumatosis cystoides intestinalis in an elderly patient, better to be safe than sorry. 61
32280437 2020
21
Full-thickness resection of subepithelial nodules, allowing for the diagnosis of an unusual case of pneumatosis cystoides intestinalis. 61
32154485 2020
22
Pneumatosis cystoides intestinalis: case report and review of literature. 61
31161540 2020
23
Asymptomatic pneumoperitoneum in pneumatosis coli: A misleading operative indication. 61
32305029 2020
24
[Pneumatosis cystoides intestinalis developing subsequent to allogeneic hematopoietic stem cell transplantation for mixed phenotype acute leukemia]. 61
32378572 2020
25
Pneumoperitoneum and Pneumatosis cystoides intestinalis, a dangerous mixture. A case report. 61
32892124 2020
26
Mesenteric venous thrombosis as a rare complication of decompression sickness. 61
31950288 2020
27
[A Case of Pneumatosis Cystoides Intestinalis during Castration-Resistant Prostate Cancer Treatment]. 61
31933338 2019
28
Pneumatosis cystoides intestinalis linked to sunitinib treatment for renal cell carcinoma. 61
32743449 2019
29
Pneumatosis cystoides intestinalis: a case report and literature review. 61
31694581 2019
30
"Cystamatic" Review: Is Surgery Mandatory for Pneumatosis Cystoides Intestinalis? 61
31410751 2019
31
Pneumatosis cystoides intestinalis in a patient with aseptic meningitis: a case report. 61
31471694 2019
32
EFSUMB Gastrointestinal Ultrasound (GIUS) Task Force Group: Celiac sprue and other rare gastrointestinal diseases ultrasound features. 61
31476211 2019
33
Secondary pneumatosis cystoides intestinalis complicated by intestinal volvulus: A case report and literature review. 61
30661712 2019
34
Pneumatosis Cystoides Intestinalis as an Incidental Finding on Endoscopy. 61
31452500 2019
35
Pneumatosis cystoides intestinalis: A rare benign cause of chronic pain and bloating with pneumoperitoneum. 61
30638604 2019
36
Pneumatosis cystoides intestinalis in pulmonary mycobacterial disease. 61
31180773 2019
37
Chronic intestinal pseudo-obstruction with pneumatosis cystoides intestinalis in a patient with systemic sclerosis: A case report. 61
31045831 2019
38
Pneumatosis cystoides intestinalis: Not uncommon cause of free air in acute abdomen. 61
30249430 2019
39
Pneumatosis Cystoides Intestinalis with Pneumoperitoneum. 61
30917262 2019
40
Pneumatosis Cystoides Intestinalis. 61
29778913 2019
41
Pneumatosis Cystoides Intestinalis. 61
29176475 2019
42
Pneumatosis Cystoides Intestinalis Secondary to Use of an α-Glucosidase Inhibitor. 61
30644816 2019
43
Pneumatosis cystoides intestinalis revealed after a hand-to-hand aggression: A case report. 61
31493662 2019
44
Is pneumatosis cystoides intestinalis a lymphatic pathology?: A case of small bowel lymphangioma and subsequent development of pneumatosis cystoides intestinalis in a 57-year-old female. 61
30697407 2019
45
Endoscopic Fine-Needle Aspiration Is Useful for the Treatment of Pneumatosis Cystoides Intestinalis With Intussusception. 61
30633030 2019
46
Rapid reversal of colonic pneumatosis with restoration of mesenteric arterial supply. 61
29881954 2018
47
Pneumatosis cystoides intestinalis (PCI) in a patient with undiagnosed systemic sclerosis. 61
30269087 2018
48
A pneumoperitoneum due to intestinal cystic pneumatosis associated with a tyrosine kinase inhibitor. 61
29900744 2018
49
Stenotic Ischemic Enteritis with Concomitant Hepatic Portal Venous Gas and Pneumatosis Cystoides Intestinalis. 61
29491303 2018
50
Pneumatosis cystoides intestinalis: six case reports and a review of the literature. 61
29954324 2018

Variations for Pneumatosis Cystoides Intestinalis

Expression for Pneumatosis Cystoides Intestinalis

Search GEO for disease gene expression data for Pneumatosis Cystoides Intestinalis.

Pathways for Pneumatosis Cystoides Intestinalis

Pathways related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.63 SI MGAM
2 9.58 SI MGAM

GO Terms for Pneumatosis Cystoides Intestinalis

Biological processes related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of G protein-coupled receptor signaling pathway GO:0008277 9.4 GIT2 GIT1
2 potassium ion import across plasma membrane GO:1990573 9.37 ATP4A ATP12A
3 cellular sodium ion homeostasis GO:0006883 9.32 ATP4A ATP12A
4 sodium ion export across plasma membrane GO:0036376 9.26 ATP4A ATP12A
5 cellular potassium ion homeostasis GO:0030007 9.16 ATP4A ATP12A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.96 ATP4A ATP12A
7 polysaccharide digestion GO:0044245 8.62 SI MGAM

Molecular functions related to Pneumatosis Cystoides Intestinalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 9.32 SI MGAM
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.26 ATP4A ATP12A
3 potassium-transporting ATPase activity GO:0008556 9.16 ATP4A ATP12A
4 alpha-1,4-glucosidase activity GO:0004558 8.96 SI MGAM
5 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Pneumatosis Cystoides Intestinalis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....