Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
PCP
MCID: PNM001
MIFTS: 53

Pneumocystosis (PCP)

Categories: Immune diseases, Infectious diseases, Rare diseases, Respiratory diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Pneumocystosis

About this section

MalaCards integrated aliases for Pneumocystosis:

Name: Pneumocystosis 12 76 53 59 15
Pneumocystis Carinii Pneumonia 12 15
Pneumocystis Pneumonia 12 3
Pcp 48 3
Pneumocystis Jirovecii Pneumonia 12
Pneumocystis Jiroveci Pneumonia 73
Pneumonia Pneumocystis Carinii 55
Pneumocystosis Pneumonia 12
Pulmonary Pneumocystosis 12
Pneumonia, Pneumocystis 44

Characteristics:

Orphanet epidemiological data:

59
pneumocystosis
Inheritance: Not applicable; Age of death: any age;

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Respiratory diseases Skin diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 33
Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:11339
ICD10 33 B59
ICD9CM 35 136.3
MeSH 44 D011020
NCIt 50 C3334
SNOMED-CT 68 57541005 88860002
Orphanet 59 ORPHA723
ICD10 via Orphanet 34 B59+ J17.3*
UMLS via Orphanet 74 C1535939
UMLS 73 C1535939
Sources

Summaries for Pneumocystosis

About this section
NIH Rare Diseases : 53 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 723Disease definitionHuman pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localised to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.Visit the Orphanet disease page for more resources.

MalaCards based summary : Pneumocystosis, also known as pneumocystis carinii pneumonia, is related to respiratory failure and acquired immunodeficiency syndrome. An important gene associated with Pneumocystosis is CD4 (CD4 Molecule), and among its related pathways/superpathways are Bacterial infections in CF airways and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Sertraline and Bupropion have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and bone, and related phenotypes are homeostasis/metabolism and immune system

Disease Ontology : 12 An opportunistic mycosis that is located in lungs, but can also occur in eyes, ears, skin, thyroid, pituitary, palate, parathyroid, esophagus, pleura, heart, liver, spleen, small intestine, adrenals, kidneys, bone marrow, and lymph nodes, has material basis in Pneumocystis jirovecii that effects interstitial and alveolar tissues and has symptom nonproductive cough, has symptom shortness of breath, and has symptom fever.

CDC : 3 Pneumocystis jirovecii in the lung of an HIV/AIDS patient.

Wikipedia : 76 Pneumocystosis is an infection by Pneumocystis jirovecii, that primarily occurs as a pulmonary infection... more...

Sources

Related Diseases for Pneumocystosis

About this section

Diseases related to Pneumocystosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 240)
# Related Disease Score Top Affiliating Genes
1 respiratory failure 31.0 ALB SFTPD TNF
2 acquired immunodeficiency syndrome 30.6 ALB CD4 TNF
3 toxoplasmosis 30.3 CD40LG DHFR TNF
4 invasive aspergillosis 30.3 CLEC7A FLNC SFTPD
5 connective tissue disease 30.2 CD40LG MUC1 SFTPD TNF
6 aspergillosis 30.0 CLEC7A SFTPD TNF
7 pneumonia 30.0 CD40LG DHPS SFTPD TNF
8 viral infectious disease 29.9 CD4 CD40LG TNF
9 cryptosporidiosis 29.9 CD40LG DHFR
10 schistosomiasis 29.8 ALB CD40LG TNF
11 hematopoietic stem cell transplantation 29.8 CLEC7A TNF
12 interstitial lung disease 29.6 MUC1 SFTPD TNF
13 hepatitis e 29.5 ALB CD40LG TNF
14 phencyclidine abuse 11.9
15 immunodeficiency with hyper-igm, type 1 11.8
16 human immunodeficiency virus infectious disease 10.8
17 encephalitis 10.6
18 arthritis 10.6
19 systemic lupus erythematosus 10.5
20 rheumatoid arthritis 10.5
21 lupus erythematosus 10.5
22 pneumothorax 10.5
23 bacterial pneumonia 10.5
24 leukemia 10.5
25 colitis 10.5
26 breast cancer 10.4
27 ulcerative colitis 10.4
28 lymphocytic leukemia 10.4
29 agammaglobulinemia 10.4
30 pulmonary tuberculosis 10.4
31 cytomegalovirus infection 10.4
32 asthma 10.3
33 leukemia, acute lymphoblastic 10.3
34 pancytopenia 10.3
35 tropical calcific pancreatitis 10.3
36 pneumothorax, primary spontaneous 10.3
37 human immunodeficiency virus type 1 10.3
38 lymphoma 10.3
39 infantile epileptic encephalopathy 10.3
40 cytomegalic inclusion disease 10.3
41 rheumatic disease 10.2
42 anca-associated vasculitis 10.2
43 severe combined immunodeficiency 10.2
44 dermatomyositis 10.2
45 methemoglobinemia 10.2
46 conn's syndrome 10.2
47 congenital hypogammaglobulinemia 10.2
48 oral candidiasis 10.2
49 chronic mucocutaneous candidiasis 10.2
50 dyskeratosis congenita 10.2

Comorbidity relations with Pneumocystosis via Phenotypic Disease Network (PDN):


Deficiency Anemia Heart Disease
Neutropenia Oral Candidiasis
Postinflammatory Pulmonary Fibrosis Respiratory Failure

Graphical network of the top 20 diseases related to Pneumocystosis:



Diseases related to Pneumocystosis
Sources

Symptoms & Phenotypes for Pneumocystosis

About this section

MGI Mouse Phenotypes related to Pneumocystosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 ALB CD4 CD40LG CLEC7A DHFR DHPS
2 immune system MP:0005387 9.56 CD4 CD40LG CLEC7A DHFR DHPS SFTPD
3 mortality/aging MP:0010768 9.28 ALB CD4 CD40LG CLEC7A DHFR DHPS
Sources

Drugs & Therapeutics for Pneumocystosis

About this section

Drugs for Pneumocystosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 377)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sertraline Approved Phase 4,Not Applicable 79617-96-2 68617
2
Bupropion Approved Phase 4,Not Applicable 34841-39-9, 34911-55-2 444
3
leucovorin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 58-05-9 6006 143
4
Trimethoprim Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 738-70-5 5578
5
Sulfamethoxazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 723-46-6 5329
6
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22916-47-8 4189
7
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
9
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 302-25-0
10
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2921-57-5
11
Pentamidine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 100-33-4 4735
12
Budesonide Approved Phase 4,Not Applicable 51333-22-3 63006 5281004
13
Phentermine Approved, Illicit Phase 4 122-09-8 4771
14
Topiramate Approved Phase 4 97240-79-4 5284627
15
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
16
Heparin Approved, Investigational Phase 4,Phase 1 9005-49-6 772 46507594
17
Dalteparin Approved Phase 4,Phase 1 9005-49-6
18
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
19
Ethanol Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 64-17-5 702
20
Acamprosate Approved, Investigational Phase 4 77337-76-9 71158
21
Metronidazole Approved Phase 4,Not Applicable 443-48-1 4173
22 Strawberry Approved Phase 4
23
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
24
Mycophenolic acid Approved Phase 4,Phase 3,Phase 1,Phase 2 24280-93-1 446541
25
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 1 155213-67-5 392622
26
Emtricitabine Approved, Investigational Phase 4,Phase 1,Phase 2 143491-57-0 60877
27
Nevirapine Approved Phase 4 129618-40-2 4463
28
Methylphenidate Approved, Investigational Phase 4,Phase 1 113-45-1 4158
29
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
30
Dapsone Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 80-08-0 2955
31
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Not Applicable 18323-44-9 29029
32
Prednisone Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 53-03-2 5865
33
Atovaquone Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 95233-18-4 74989
34
Primaquine Approved Phase 4,Phase 3,Not Applicable 90-34-6 4908
35
Morphine Approved, Investigational Phase 4,Phase 1,Not Applicable 57-27-2 5288826
36
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
37
Sumatriptan Approved, Investigational Phase 4 103628-46-2 5358
38
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
39
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59-30-3 6037
40
Glutamic Acid Approved, Nutraceutical Phase 4 56-86-0 33032
41
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
42
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
43
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 5280795 6221
44
Prednisolone hemisuccinate Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2920-86-7
45
Tenofovir Experimental, Investigational Phase 4 147127-20-6 464205
46 Psychotropic Drugs Phase 4,Phase 1,Not Applicable
47 Serotonin Agents Phase 4
48 Serotonin Uptake Inhibitors Phase 4
49 Neurotransmitter Agents Phase 4,Phase 1,Phase 2,Not Applicable
50 Neurotransmitter Uptake Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 530)
# Name Status NCT ID Phase Drugs
1 Depression Care Management for Depressed Elders in China Primary Care Unknown status NCT01287494 Phase 4 Sertraline
2 Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia Prophylaxis Completed NCT00000816 Phase 4 Sulfamethoxazole-Trimethoprim
3 Evaluation of LEVITRA to Advance the Treatment of Erectile Dysfunction Completed NCT00664833 Phase 4
4 Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations Completed NCT01167452 Phase 4 Sulfamethoxazole/trimethoprim
5 A Toolbox Approach to Obesity Treatment in Primary Care Completed NCT01922934 Phase 4 Obesity pharmacotherapy
6 Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events Completed NCT01417949 Phase 4
7 EMD and/or Bone Substitute for the Treatment of Class II Furcations Completed NCT02474498 Phase 4 EMD
8 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. Completed NCT02487186 Phase 4 Doxicicline
9 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
10 Deferment of Imaging for Pulmonary Embolism Completed NCT00381511 Phase 4 low molecular weight heparin
11 Pharmacokinetics of Micafungin During Continuous Venovenous Hemofiltration Completed NCT02651038 Phase 4 Micafungin
12 Biomarker Study of Acamprosate in Schizophrenia Completed NCT00688324 Phase 4 Acamprosate
13 The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis Completed NCT02023840 Phase 4 metronidazole gel;placebo
14 Acute Otitis Media (AOM) Therapy Trial in Young Children Completed NCT00377260 Phase 4 amoxicillin-clavulanate;Placebo
15 VITamine D Supplementation in RenAL Transplant Recipients - VITALE Completed NCT01431430 Phase 4 Cholecalciferol 100 000 UI;Cholecalciferol 12 000 UI
16 A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation Completed NCT00048165 Phase 4 Daclizumab;Methylprednisolone;Mycophenolate mofetil;Placebo;cyclosporine
17 Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT) Completed NCT00552240 Phase 4 tenofovir DF 300 mg QD;tenofovir DF 300 mg QD;emtricitabine 200 mg QD;emtricitabine 200 mg QD;Nevirapine 200 mg BID;Atazanavir 300 mg;Ritonavir 100 mg
18 Methylphenidate Treatment of Attention Deficits in Epilepsy Completed NCT02178995 Phase 4 Methylphenidate
19 Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant Bacteria Recruiting NCT03087890 Phase 4 Cotrimoxazole;Placebo
20 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4 Dapsone
21 A Prospective Evaluation of Natriuretic Peptide Based Referral of CHF Patients in Primary Care Recruiting NCT02807857 Phase 4
22 Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients Enrolling by invitation NCT01817699 Phase 4
23 A Prospective Cohort Study to Improve HCV Care in Dialysis Patients Not yet recruiting NCT03791814 Phase 4 Zepatier
24 Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department Not yet recruiting NCT02945839 Phase 4 Preventative Medication (PM)
25 Approaches To Therapy Escalation In T2D Not yet recruiting NCT03813316 Phase 4 DPP-4 inhibitor;SGLT2 inhibitor;SGLT2 inhibitor and DPP-4 inhibitor
26 Dissemination of Prostate Cancer Screening to PCP's in African American Communities Terminated NCT00629330 Phase 4
27 Conversion to Embeda With Rescue Trial Terminated NCT01179191 Phase 4 morphine sulfate and naltrexone hydrochloride (EMBEDA)
28 Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP) Withdrawn NCT00636935 Phase 4 Antibiotics only;Antibiotics + Corticosteroids;Corticosteroids + antibiotics
29 Pulmicort Respules on Relapse Rates After Treatment in the ED Withdrawn NCT00584636 Phase 4 pulmicort respules
30 Study of Trimethoprim/Sulfamethoxazole as PCP Prophylaxis in CTD Patients Unknown status NCT01747278 Phase 2, Phase 3 Trimethoprim/Sulfamethoxazole
31 Efficacy of Phytolacca Decandra and Melissa Officinalis in Children With Nocturnal Bruxism Unknown status NCT02870543 Phase 3 Phytolacca decandra;Melissa officinalis;Phyt.decandra + Melissa offic.
32 Dementia Early Recognition and Response in Primary Care Unknown status NCT00866099 Phase 2, Phase 3
33 A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides Completed NCT00001028 Phase 3 Pentamidine isethionate;Dapsone
34 A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides Completed NCT00000802 Phase 3 Atovaquone;Dapsone
35 A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected Patients Completed NCT00000748 Phase 3 Sulfamethoxazole-Trimethoprim
36 A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia Completed NCT00000724 Phase 3 Trimetrexate glucuronate;Leucovorin calcium
37 A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies Completed NCT00001016 Phase 3 Trimetrexate glucuronate;Leucovorin calcium
38 Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Completed NCT00001014 Phase 3 Trimetrexate glucuronate;Sulfamethoxazole-Trimethoprim;Leucovorin calcium
39 A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS Completed NCT00000715 Phase 3 Pentamidine isethionate;Sulfamethoxazole-Trimethoprim
40 A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) Completed NCT00000727 Phase 3 Pentamidine isethionate;Pyrimethamine;Sulfamethoxazole/Trimethoprim;Sulfadoxine/Pyrimethamine;Zidovudine
41 An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies Completed NCT00000714 Phase 3 Trimetrexate glucuronate;Leucovorin calcium
42 A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX Completed NCT00002340 Phase 3 Atovaquone;Pentamidine isethionate
43 Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Completed NCT00001013 Phase 3 Trimetrexate glucuronate;Pentamidine isethionate;Sulfamethoxazole-Trimethoprim;Leucovorin calcium
44 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed NCT00000640 Phase 3 Primaquine;Sulfamethoxazole-Trimethoprim;Dapsone;Clindamycin
45 Virtual Continuity and Its Impact on Complex Hospitalized Patients' Care Completed NCT01397253 Phase 3
46 A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients Completed NCT00000991 Phase 3 Pentamidine isethionate;Sulfamethoxazole-Trimethoprim;Dapsone;Zidovudine
47 A Randomized, Unblinded Trial of Zidovudine Versus ddC in the Treatment of Patients Status Post PCP Who Received Long-Term Zidovudine Therapy in Protocol ACTG 002 Completed NCT00000682 Phase 3 Zidovudine;Zalcitabine
48 A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCP Completed NCT00000700 Phase 3 Zidovudine
49 The Congestive Heart Failure Adherence Redesign Trial Completed NCT01698242 Phase 3
50 Using Social Incentives and Gamification for Weight Loss Promotion Completed NCT02564445 Phase 3

Search NIH Clinical Center for Pneumocystosis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: pneumonia, pneumocystis

Sources

Genetic Tests for Pneumocystosis

About this section
Sources

Anatomical Context for Pneumocystosis

About this section

MalaCards organs/tissues related to Pneumocystosis:

41
Lung, Skin, Bone, Liver, Bone Marrow, Kidney, Heart
Sources

Publications for Pneumocystosis

About this section

Articles related to Pneumocystosis:

(show top 50) (show all 1179)
# Title Authors Year
1
Pneumocystosis and quantitative PCR. ( 29789160 )
2018
2
Pneumocystosis in dogs: meta-analysis of 43 published cases including clinical signs, diagnostic procedures, and treatment. ( 29145787 )
2018
3
CT findings in Pneumocystis carinii pneumonia in five dogs. ( 29577303 )
2018
4
The changing trends and profile of pneumocystosis mortality in the United States, 1999-2014. ( 28568970 )
2017
5
Multiple myeloma presenting with bilateral ankle pain (microangiopathy) and complicated by streptococcal meningitis and Pneumocystis carinii pneumonia. ( 28174184 )
2017
6
Pneumocystosis revealing immunodeficiency secondary to<i>TERC</i>mutation. ( 29167304 )
2017
7
Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring. ( 27890037 )
2017
8
The lung microbiome in patients with pneumocystosis. ( 29202739 )
2017
9
Risk factors for mortality from pneumocystis carinii pneumonia (PCP) in non-HIV patients: a meta-analysis. ( 28938676 )
2017
10
Serological diagnosis of pneumocystosis: production of a synthetic recombinant antigen for immunodetection of Pneumocystis jirovecii. ( 27824115 )
2016
11
Increased dosage of infliximab is a potential cause of Pneumocystis carinii pneumonia. ( 26839596 )
2016
12
Common variable immune deficiency in a Pomeranian with Pneumocystis carinii pneumonia. ( 25715954 )
2015
13
Pneumocystis and Pneumocystosis: first meeting of experts from Latin-American and Portuguese-speaking countries - a mini-review. ( 24617414 )
2014
14
Adjunctive glucocorticoid therapy for non-HIV-related pneumocystis carinii pneumonia (NH-PCP). ( 24666835 )
2014
15
Histopathology of Pneumocystis carinii pneumonia in immunocompetent laboratory rats. ( 25009598 )
2014
16
Efficacy of caspofungin, a 1,3-β-D-glucan synthase inhibitor, on Pneumocystis carinii pneumonia in rats. ( 25288652 )
2014
17
Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review. ( 24275372 )
2013
18
Clinical outcomes of Pneumocystis carinii pneumonia in adult liver transplant recipients. ( 24157035 )
2013
19
Pneumocystosis in a patient with Crohn's disease treated with combination therapy with adalimumab. ( 22398055 )
2012
20
Pneumocystis carinii pneumonia in gastric cancer patients without acquired immune deficiency syndrome: 3 cases report and literature review. ( 22792534 )
2012
21
Chitinases in Pneumocystis carinii pneumonia. ( 22535444 )
2012
22
Dynamics of Pneumocystis carinii air shedding during experimental pneumocystosis. ( 21372312 )
2011
23
Pneumocystosis: a network survey in the Paris area 2003-2008. ( 21229281 )
2011
24
Epidemiological characteristics of pulmonary pneumocystosis and concurrent infections in pigs in Jeju Island, Korea. ( 21368558 )
2011
25
Pneumocystis carinii pneumonia prophylaxis: current therapies and recommendations. ( 21636828 )
2011
26
Development of Pneumocystis carinii pneumonia in patients with immunobullous and connective tissue disease receiving immunosuppressive medications. ( 19828210 )
2010
27
Risk of pneumocystosis after early discontinuation of prophylaxis among HIV-infected patients receiving highly active antiretroviral therapy. ( 20492660 )
2010
28
Pneumocystis carinii pneumonia in a HIV-positive patient. ( 20726370 )
2010
29
Late-onset and atypical presentation of Pneumocystis carinii pneumonia in a renal transplant recipient. ( 18758701 )
2009
30
Screening Pneumocystis carinii pneumonia in non-HIV-infected immunocompromised patients using polymerase chain reaction. ( 19631093 )
2009
31
Predictors of pneumocystosis or tuberculosis in HIV-infected Asian patients with AFB smear-negative sputum pneumonia. ( 18645508 )
2008
32
Activity of propolis in an experimental model of pneumocystosis. ( 18690302 )
2008
33
Splenic pneumocystosis: an atypical presentation of extrapulmonary Pneumocystis infection. ( 18975440 )
2008
34
Central retinal vein occlusion in an AIDS patient with presumed Pneumocystis carinii pneumonia. ( 18443615 )
2008
35
Otic pneumocystosis in acquired immune deficiency syndrome. ( 18496145 )
2008
36
S-adenosylmethionine levels in the diagnosis of Pneumocystis carinii pneumonia in patients with HIV infection. ( 18177224 )
2008
37
[Pneumocystis carinii pneumonia in a patient with hyper-IgE syndrome]. ( 17554982 )
2007
38
Cystic pneumocystosis in a patient with AIDS. ( 17992424 )
2007
39
Pneumocystis carinii pneumonia in an infant with hypogammaglobulinemia. ( 17165040 )
2007
40
Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia. ( 17345613 )
2007
41
A background and critical analysis of the treatment of pneumocystis carinii pneumonia (PCP) in HIV/AIDS. ( 17441498 )
2007
42
Pneumocystis carinii pneumonia in a rheumatoid arthritis patient treated with adalimumab. ( 17464877 )
2007
43
Pneumocystis carinii pneumonia in immunocompromised host--an autopsy report of three cases. ( 17474255 )
2007
44
Usefulness of beta-D glucan in diagnosing Pneumocystis carinii pneumonia and monitoring its treatment in a living-donor liver-transplant recipient. ( 17520208 )
2007
45
Patients receiving standard-dose temozolomide therapy are at risk of Pneumocystis carinii pneumonia. ( 17644327 )
2007
46
Pneumocystis carinii pneumonia in infant treated with oral steroids for hemangioma. ( 17875903 )
2007
47
Pneumocystis carinii pneumonia in a patient on etanercept for psoriatic arthritis. ( 17906888 )
2007
48
The 'dark bronchus' sign: HRCT diagnosis of Pneumocystis carinii pneumonia. ( 19724672 )
2007
49
Pneumocystosis: survey and DHPS genotype analysis in 14 Parisian hospitals in 2003 and 2004. ( 17169018 )
2006
50
Pneumocystis jirovecii genotypes and granulomatous pneumocystosis. ( 16580165 )
2006
Sources

Variations for Pneumocystosis

About this section
Sources

Expression for Pneumocystosis

About this section
Search GEO for disease gene expression data for Pneumocystosis.
Sources

Pathways for Pneumocystosis

About this section

Pathways related to Pneumocystosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Bacterial infections in CF airways 22
Show member pathways
 11.65 MUC1 SFTPD TNF
2
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.4 CD4 GYPA TNF
3
Hematopoietic cell lineage 37
11.12 CD4 GYPA TNF
4
Antifolate resistance 37
10.86 DHFR TNF
5
Cytokines and Inflammatory Response 1
10.78 CD4 TNF
6
Malaria 37
10.49 CD40LG GYPA TNF
Sources

GO Terms for Pneumocystosis

About this section

Biological processes related to Pneumocystosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of immunoglobulin secretion GO:0051023 8.62 CD40LG TNF

Molecular functions related to Pneumocystosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.73 ALB CD4 CD40LG CLEC7A DHFR DHPS
2 tumor necrosis factor receptor binding GO:0005164 9.16 CD40LG TNF
3 identical protein binding GO:0042802 9.1 ALB CD4 DHPS GYPA SFTPD TNF
Sources

Sources for Pneumocystosis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....