Aliases & Classifications for Pneumothorax

MalaCards integrated aliases for Pneumothorax:

Name: Pneumothorax 12 77 38 30 56 6 45 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1673
KEGG 38 H01110
MeSH 45 D011030
ICD10 34 J93 J93.1 J93.9

Summaries for Pneumothorax

MalaCards based summary : Pneumothorax is related to pneumothorax, primary spontaneous and birt-hogg-dube syndrome, and has symptoms including dyspnea and hemoptysis. An important gene associated with Pneumothorax is FLCN (Folliculin), and among its related pathways/superpathways are Glioma and Degradation of the extracellular matrix. The drugs Benzocaine and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and heart, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 77 A pneumothorax is an abnormal collection of air in the pleural space between the lung and the chest... more...

Related Diseases for Pneumothorax

Diseases related to Pneumothorax via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 399)
# Related Disease Score Top Affiliating Genes
1 pneumothorax, primary spontaneous 34.3 BLVRA FLCN FNIP1
2 birt-hogg-dube syndrome 32.2 FLCN FNIP1 FNIP2
3 pleural disease 32.0 FLCN FNIP1 FNIP2
4 marfan syndrome 30.5 ELN FBN1 MMP2
5 pulmonary disease, chronic obstructive 30.3 ELN MMP9 SERPINA1
6 lung disease 30.2 ELN MMP9 SERPINA1 TSC1
7 pulmonary emphysema 30.2 ELN MMP9 SERPINA1
8 lymphangioleiomyomatosis 30.2 ELN MMP2 PGR TSC1
9 inguinal hernia 29.9 ELN FBN1 MMP2 MMP9
10 congenital heart defects, hamartomas of tongue, and polysyndactyly 29.8 FLCN TSC1
11 aortic aneurysm, familial thoracic 1 29.6 ELN FBN1 MMP2
12 aortic aneurysm, familial abdominal, 1 29.4 ELN FBN1 MMP2 MMP9
13 perivascular epithelioid cell tumor 29.4 MUC1 PGR
14 connective tissue disease 29.2 COL5A1 ELN FBN1 MUC1
15 lung cancer susceptibility 3 29.0 ALK KDR MMP2 MMP9 MUC1 NFE2L2
16 renal cell carcinoma, nonpapillary 28.8 FLCN KDR MMP2 MMP9 MUC1 TSC1
17 catamenial pneumothorax 12.6
18 tuberculous pneumothorax 12.4
19 spontaneous tension pneumothorax 12.4
20 pulmonary bullae causing pneumothorax 12.1
21 hemopneumothorax 11.5
22 hereditary multiple osteochondromas 11.4
23 pneumonia 10.5
24 endometriosis 10.5
25 extracranial arteriovenous malformation 10.4 MMP2 MMP9
26 focal myositis 10.4 MMP2 MMP9
27 sarcoma 10.4
28 pulmonary edema 10.4
29 villous adenocarcinoma 10.4 MMP2 MMP9
30 spastic entropion 10.4 MMP2 MMP9
31 lentigo maligna melanoma 10.4 MMP2 MMP9
32 psammomatous meningioma 10.4 MMP2 MMP9
33 acute transverse myelitis 10.3 MMP2 MMP9
34 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.3 ELN FBN1
35 late-onset focal dermal elastosis 10.3 ELN FBN1
36 ehlers-danlos syndrome, vascular type 10.3 COL5A1 ELN
37 familial abdominal aortic aneurysm 10.3 ELN FBN1
38 ischemic colitis 10.3 MMP2 MMP9
39 cerebral aneurysms 10.3 ELN MMP2
40 light chain deposition disease 10.3 MMP2 MMP9
41 lung papillary adenocarcinoma 10.3 ALK NFE2L2
42 histiocytosis 10.3
43 conjunctival nevus 10.3 MMP2 MMP9
44 mid-dermal elastolysis 10.3 ELN FBN1
45 lung cancer 10.3
46 langerhans cell histiocytosis 10.3
47 autosomal recessive cutis laxa type iii 10.3 ELN FBN1
48 parotitis 10.3 MMP2 MMP9
49 pulmonary tuberculosis 10.3
50 angiokeratoma circumscriptum 10.3 KDR MMP9

Graphical network of the top 20 diseases related to Pneumothorax:



Diseases related to Pneumothorax

Symptoms & Phenotypes for Pneumothorax

UMLS symptoms related to Pneumothorax:


dyspnea, hemoptysis

MGI Mouse Phenotypes related to Pneumothorax:

47 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 ALK BLVRA FBN1 FLCN FNIP1 FNIP2
2 cardiovascular system MP:0005385 10.19 COL5A1 FBN1 FLCN FNIP1 KDR MMP2
3 cellular MP:0005384 10.18 BLVRA FBN1 FLCN FNIP1 FNIP2 KDR
4 mortality/aging MP:0010768 10.15 ALK COL5A1 FBN1 FLCN FNIP1 FNIP2
5 integument MP:0010771 10.01 ALK COL5A1 FBN1 KDR MMP9 NFE2L2
6 embryo MP:0005380 10 COL5A1 FBN1 FLCN KDR NFE2L2 PGR
7 neoplasm MP:0002006 9.91 ALK FLCN FNIP1 FNIP2 MMP2 MMP9
8 muscle MP:0005369 9.87 FBN1 FNIP1 KDR MMP2 MMP9 PGR
9 renal/urinary system MP:0005367 9.7 FBN1 FLCN FNIP1 FNIP2 MMP9 NFE2L2
10 respiratory system MP:0005388 9.5 ALK FBN1 KDR MMP2 MMP9 NFE2L2
11 skeleton MP:0005390 9.23 ALK FBN1 KDR MMP2 MMP9 NFE2L2

Drugs & Therapeutics for Pneumothorax

Drugs for Pneumothorax (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 255)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
2
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
3
tannic acid Approved Phase 4,Phase 2,Phase 3,Not Applicable 1401-55-4
4
Desflurane Approved Phase 4 57041-67-5 42113
5
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 1177-87-3
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-02-2 5743
7
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2180-92-9, 38396-39-3 2474
8
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
9
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
10
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
11
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
12
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 137-58-6 3676
13 Poractant alfa Approved Phase 4,Phase 2,Phase 3,Not Applicable 129069-19-8
14
Betamethasone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 378-44-9 9782
15
Mepivacaine Approved, Vet_approved Phase 4,Not Applicable 96-88-8 4062
16
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 113775-47-6 68602 5311068
17
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
18
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
19
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Not Applicable 84057-95-4 71273 175805
20
Hydromorphone Approved, Illicit Phase 4,Not Applicable 466-99-9 5284570
21
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 57-27-2 5288826
22
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
23
Nitrous oxide Approved, Vet_approved Phase 4,Not Applicable 10024-97-2 948
24
Racepinephrine Approved Phase 4,Phase 3,Not Applicable 329-65-7 838
25
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 51-43-4 5816
26
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
27
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
28
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3 18323-44-9 29029
29
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
30
Remifentanil Approved Phase 4,Phase 1,Phase 2,Not Applicable 132875-61-7 60815
31
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
32
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
33
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
34 Pulmonary Surfactants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Platelet Aggregation Inhibitors Phase 4,Not Applicable
37 Anesthetics, General Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
39 Anesthetics, Inhalation Phase 4,Not Applicable
40 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Calamus Phase 4,Phase 2,Phase 3,Not Applicable
42 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Not Applicable
43 Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
44 Antiemetics Phase 4,Phase 2,Phase 3,Not Applicable
45 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Not Applicable
46 glucocorticoids Phase 4,Phase 3,Phase 2,Not Applicable
47 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
48 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Not Applicable
49 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 607)
# Name Status NCT ID Phase Drugs
1 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
2 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
3 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
4 Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum Unknown status NCT01486953 Phase 4 Desflurane;Sevoflurane
5 Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function Unknown status NCT02509754 Phase 4
6 High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis Unknown status NCT03015051 Phase 4 Oxygen
7 Dexamethasone Dose in Low Volume Bupivacaine USG Supraclavicular Block Unknown status NCT03043495 Phase 4 Dexamethasone
8 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
9 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
10 Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery Completed NCT01735851 Phase 4 Thoracic epidural analgesia
11 Safety And Accuracy Study Of The Actisight™ Needle Guidance System In Patients Undergoing CT-Guided Procedures Completed NCT01040884 Phase 4
12 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications Completed NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
13 Multimodal Analgesic Technique for Control of Post-laproscopy Abdominal Pain Completed NCT03241602 Phase 4 Intraperitoneal lidocaine
14 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Completed NCT00964392 Phase 4
15 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
16 Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants Completed NCT02233985 Phase 4 0.9% Sodium Chloride;3% Sodium Chloride
17 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
18 A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
19 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
20 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
21 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
22 Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Completed NCT01403623 Phase 4
23 ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial Completed NCT00164047 Phase 4 Nitrous Oxide
24 Effect of Dexamethasone Dose and Route on Duration of Interscalene Block After Outpatient Shoulder Surgery Completed NCT02426736 Phase 4 Dexamethasone;Bupivacaine
25 The Retroclavicular Approach for Regional Anesthesia of the Upper Limb in Obese Patients Completed NCT02086643 Phase 4
26 Suprascapular and Axillary Blocks Versus Interscalene Block for Shoulder Surgery Completed NCT02517437 Phase 4 Suprascapular & axillary blocks;Interscalene block
27 OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP Recruiting NCT02140580 Phase 4
28 Is PECS Block Equivalent to Paravertebral Block in Preventing Postoperative Pain After Breast Surgery? Recruiting NCT02645474 Phase 4 Ropivacaine
29 Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU) Recruiting NCT03624881 Phase 4
30 Early Intrapleural TPA Instillation Versus Late Recruiting NCT03167281 Phase 4
31 Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome Recruiting NCT02164734 Phase 4 remifentanil
32 Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery Recruiting NCT03758261 Phase 4 Paravertebral nerve block;Erector Spinae nerve block
33 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
34 Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery Active, not recruiting NCT03270033 Phase 4 Dexamethasone;Dexmedetomidine
35 Comparative Study Between Single , Intra- Cluster and Double-injection Ultrasound-guided Supraclavicular Block of Brachial Plexus Enrolling by invitation NCT03188939 Phase 4
36 Reactor Thoracostomy Not yet recruiting NCT03769727 Phase 4
37 Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery Terminated NCT00681174 Phase 4 Morphine;oxycodone;Propofol;Remifentanil;Paracetamol;Morphine
38 Pain Management After Total Shoulder Arthroplasty Terminated NCT03219983 Phase 4 Ropivacaine;liposomal bupivacaine
39 Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma Terminated NCT00557752 Phase 4
40 Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP) Withdrawn NCT00636935 Phase 4 Antibiotics only;Antibiotics + Corticosteroids;Corticosteroids + antibiotics
41 Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax Unknown status NCT01848860 Phase 2, Phase 3
42 Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax Unknown status NCT00418392 Phase 3
43 Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax Unknown status NCT01537289 Phase 3
44 Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Unknown status NCT00713362 Phase 2, Phase 3
45 Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax Unknown status NCT00270751 Phase 2, Phase 3
46 Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax Unknown status NCT00154895 Phase 3 intrapleural minocycline instillation
47 Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure Unknown status NCT01379820 Phase 2, Phase 3
48 Comparing Diagnostic Yield Between R-EBUS Guided Cryo Biopsy Vs. CT Guided Biopsy for PPL Unknown status NCT02395939 Phase 3
49 Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection Unknown status NCT00841750 Phase 3
50 Efficacy and Safety of Sirolimus for Treating Lymphangioleiomyomatosis (LAM) Unknown status NCT00414648 Phase 3 Sirolimus;Placebo sirolimus

Search NIH Clinical Center for Pneumothorax

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: pneumothorax

Genetic Tests for Pneumothorax

Genetic tests related to Pneumothorax:

# Genetic test Affiliating Genes
1 Pneumothorax 30

Anatomical Context for Pneumothorax

MalaCards organs/tissues related to Pneumothorax:

42
Lung, Breast, Heart, Kidney, Liver, Bone, Testes

Publications for Pneumothorax

Articles related to Pneumothorax:

(show top 50) (show all 4306)
# Title Authors Year
1
A Case with Concomitant Spontaneous Tension Pneumothorax and Acute Myocardial Infarction. ( 30626814 )
2019
2
Endobronchial treatment of persistent pneumothorax in acute respiratory distress syndrome. ( 30799041 )
2019
3
Incidental detection of asymptomatic pneumothorax resulting in a diagnosis of Birt-Hogg-Dubé syndrome. ( 30696655 )
2019
4
Large air-filled intrapulmonary bronchogenic cyst associated with tension pneumothorax during air travel. ( 30837238 )
2019
5
Tissue Graft to Cover Diaphragmatic Defects in a Patient With Catamenial Pneumothorax. ( 30278166 )
2019
6
Catamenial Pneumothorax, a Commonly Misdiagnosed Thoracic Condition: Multicentre Experience and Audit of a Small Case Series With Review of the Literature. ( 30853525 )
2019
7
Spontaneous pneumothorax and hemothorax frequently precede the arterial and intestinal complications of vascular Ehlers-Danlos syndrome. ( 30793832 )
2019
8
Ibrutinib Caused Mediastinal Emphysema and Pneumothorax in the Treatment of a Patient with Mantle Cell Lymphoma. ( 30790080 )
2019
9
Idiopathic pleuroparenchymal fibroelastosis presenting as bilateral spontaneous pneumothorax: A case report. ( 30604712 )
2019
10
Surgical Treatment of Spontaneous Pneumothorax: Pleural Abrasion or Pleurectomy? ( 30499890 )
2019
11
Spontaneous pneumothorax resulting in tension physiology. ( 30509377 )
2019
12
Does Ipsilateral-Dependent Positioning During Percutaneous Lung Biopsy Decrease the Risk of Pneumothorax? ( 30540211 )
2019
13
Manual aspiration versus chest tube drainage in primary spontaneous pneumothorax without underlying lung diseases: a meta-analysis of randomized controlled trials. ( 30608581 )
2019
14
Dry Needling-Induced Pneumothorax. ( 30615043 )
2019
15
New insights and improved strategies for the management of primary spontaneous pneumothorax. ( 30615303 )
2019
16
Case Image: An unusual coexistence: Spontaneous pneumopericardium and pneumothorax. ( 30628907 )
2019
17
Atypical presentation of a pneumothorax after ultrasound-guided venous jugular cannulation. ( 30630611 )
2019
18
How spontaneous pneumothorax is managed in emergency departments: a French multicentre descriptive study. ( 30634911 )
2019
19
A successful surgical repair of intraoperative pneumothorax and the diffuse dissection of visceral pleura during liver transplantation surgery via trans-diaphragmatic approach. ( 30644000 )
2019
20
Pneumocystis jirovecii-related spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema in a liver transplant recipient: a case report. ( 30658592 )
2019
21
Reducing the risk of pneumothorax following erector spinae plane block. ( 30660813 )
2019
22
Approach to pneumothorax surgery: a national survey of current UK practice. ( 30661376 )
2019
23
Neo-generation of neogenetic bullae after surgery for spontaneous pneumothorax in young adults: a prospective study. ( 30674336 )
2019
24
The Genetics of Pneumothorax. ( 30681372 )
2019
25
Cervicofacial Emphysema, Pneumomediastinum and Pneumothorax Caused by a Dental Procedure. ( 30700366 )
2019
26
Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn. ( 30707441 )
2019
27
Spontaneous Pneumothorax in a Young Woman. ( 30710545 )
2019
28
Ultrasonography Application for Detection and Management of Pneumothorax following Pleural Catheter Insertion; A Case Report. ( 30719473 )
2019
29
Cabozantinib-related pneumothorax in rapidly responding patients with renal cell carcinoma. ( 30723040 )
2019
30
Applying Fibrin Glue under Pleurography for Intractable Secondary Spontaneous Pneumothorax. ( 30727011 )
2019
31
A 46-Year-Old Woman With an Uncommon Case of Massive Pneumothorax. ( 30732698 )
2019
32
Extraperitoneal gas leakage causing pneumothorax after low rectal submucosal dissection. ( 30735022 )
2019
33
Bilateral pneumothorax after pacemaker placement "Buffalo chest". ( 30740301 )
2019
34
A Bulging Chest Wall Mass Following Pneumococcal Empyema: A Case of Pneumothorax Necessitans. ( 30742494 )
2019
35
Spontaneous pneumothorax in the elderly: a sign of a malignancy? ( 30754986 )
2019
36
Analysis of clinical and radiological features of tuberculosis associated pneumothorax. ( 30797280 )
2019
37
Early chest tube removal after surgery for primary spontaneous pneumothorax. ( 30798488 )
2019
38
Simultaneous Bilateral Primary Spontaneous Pneumothorax: A Case Report and a Review of the Literature. ( 30809412 )
2019
39
Risk Factors of Extensive Subcutaneous Emphysema after Closed-Tube Thoracostomy for Spontaneous Pneumothorax. ( 30819308 )
2019
40
Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study. ( 30823915 )
2019
41
Giant bullous emphysema mistaken for traumatic pneumothorax. ( 30826593 )
2019
42
Re-expansion pulmonary oedema in pneumothorax. ( 30826786 )
2019
43
Association of pneumothorax with use of a bougie for endotracheal intubation in a neonate. ( 30828942 )
2019
44
Letter regarding: Clinical and pathological characteristics of spontaneous pneumothorax in women: a 25-year single-institutional experience [2018;66,9:516-522]. ( 30830590 )
2019
45
Bilateral pneumothorax after general anesthesia in patient with pleomorphic sarcoma of soft tissue. ( 30834120 )
2019
46
Intratumoral Injection of Hypertonic Glucose in Treating Refractory Pneumothorax Caused by Microwave Ablation: a Preliminary Study. ( 30843091 )
2019
47
A randomized study on the effect of sequential acupoint stimulation on pulmonary function of patients with spontaneous pneumothorax during VATS perioperative period. ( 30855442 )
2019
48
Talc pleurodesis for secondary pneumothorax in elderly patients with persistent air leak. ( 30863586 )
2019
49
Post-Biopsy Manoeuvres to Reduce Pneumothorax Incidence in CT-Guided Transthoracic Lung Biopsies: A Systematic Review and Meta-analysis. ( 30863965 )
2019
50
The influence of pleurodesis on the outcome of primary spontaneous pneumothorax in children. ( 30865105 )
2019

Variations for Pneumothorax

ClinVar genetic disease variations for Pneumothorax:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 46;XY;t(20;22)(q13.3;q11.2) Translocation Uncertain significance
2 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic rs1554781700 GRCh37 Chromosome 9, 137593133: 137593133
3 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic rs1554781700 GRCh38 Chromosome 9, 134701287: 134701287

Expression for Pneumothorax

Search GEO for disease gene expression data for Pneumothorax.

Pathways for Pneumothorax

GO Terms for Pneumothorax

Cellular components related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 COL5A1 ELN FBN1 KDR MMP2 MMP9
2 extracellular matrix GO:0031012 9.35 COL5A1 ELN FBN1 MMP2 MMP9
3 collagen-containing extracellular matrix GO:0062023 9.1 COL5A1 ELN FBN1 MMP2 MMP9 SERPINA1

Biological processes related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of protein phosphorylation GO:0001932 9.54 FLCN FNIP1 FNIP2
2 positive regulation of focal adhesion assembly GO:0051894 9.48 KDR TSC1
3 positive regulation of protein complex assembly GO:0031334 9.46 FNIP1 FNIP2
4 TOR signaling GO:0031929 9.43 FLCN FNIP1
5 TORC1 signaling GO:0038202 9.4 FNIP1 FNIP2
6 extracellular matrix organization GO:0030198 9.35 COL5A1 ELN FBN1 KDR MMP9
7 negative regulation of TOR signaling GO:0032007 9.33 FLCN FNIP1 TSC1
8 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.32 MUC1 NFE2L2
9 regulation of pro-B cell differentiation GO:2000973 9.26 FLCN FNIP1
10 positive regulation of protein phosphorylation GO:0001934 8.92 FLCN FNIP1 KDR MMP9

Molecular functions related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 ALK BLVRA COL5A1 ELN FBN1 FLCN
2 identical protein binding GO:0042802 9.73 ALK FBN1 KDR MMP9 PGR SERPINA1
3 integrin binding GO:0005178 9.58 COL5A1 FBN1 KDR
4 extracellular matrix structural constituent GO:0005201 9.54 COL5A1 ELN FBN1
5 chaperone binding GO:0051087 9.5 FNIP1 FNIP2 TSC1
6 extracellular matrix constituent conferring elasticity GO:0030023 9.16 ELN FBN1
7 ATPase inhibitor activity GO:0042030 8.8 FNIP1 FNIP2 TSC1

Sources for Pneumothorax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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