Aliases & Classifications for Pneumothorax

MalaCards integrated aliases for Pneumothorax:

Name: Pneumothorax 12 76 37 29 55 6 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1673
ICD10 33 J93.1 J93 J93.9
MeSH 44 D011030
KEGG 37 H01110

Summaries for Pneumothorax

MalaCards based summary : Pneumothorax is related to pneumothorax, primary spontaneous and birt-hogg-dube syndrome, and has symptoms including dyspnea and hemoptysis. An important gene associated with Pneumothorax is FLCN (Folliculin), and among its related pathways/superpathways are Pathways in cancer and Degradation of the extracellular matrix. The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and testes, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia : 76 A pneumothorax is an abnormal collection of air in the pleural space between the lung and the chest... more...

Related Diseases for Pneumothorax

Diseases related to Pneumothorax via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 356)
# Related Disease Score Top Affiliating Genes
1 pneumothorax, primary spontaneous 34.4 BLVRA FLCN FNIP1
2 birt-hogg-dube syndrome 32.3 FLCN FNIP1 FNIP2
3 pleural disease 31.8 FLCN FNIP1 FNIP2 SLC22A4
4 marfan syndrome 30.4 ELN FBN1 MMP2
5 lung disease 30.3 ELN MMP9 SERPINA1 TSC1
6 lymphangioleiomyomatosis 30.2 ELN MMP1 MMP2 PGR TSC1
7 pulmonary disease, chronic obstructive 30.0 ELN MMP1 MMP9 SERPINA1
8 pulmonary emphysema 29.9 ELN MMP1 MMP9 SERPINA1
9 lung cancer susceptibility 3 29.7 ALK MMP2 MMP9 MUC1 NFE2L2
10 tracheal stenosis 29.5 FBN1 SLC22A4
11 inguinal hernia 29.5 ELN FBN1 MMP1 MMP2 MMP9
12 perivascular epithelioid cell tumor 29.5 MUC1 PGR
13 fibrosarcoma 29.5 MMP1 MMP2 MMP9
14 renal cell carcinoma, nonpapillary 29.4 FLCN MMP2 MMP9 MUC1 TSC1
15 kidney angiomyolipoma 29.3 FLCN FNIP1 TSC1
16 aortic aneurysm, familial thoracic 1 29.3 ELN FBN1 MMP1 MMP2 MMP9
17 connective tissue disease 29.1 ELN FBN1 MUC1
18 catamenial pneumothorax 12.6
19 tuberculous pneumothorax 12.4
20 spontaneous tension pneumothorax 12.3
21 pulmonary bullae causing pneumothorax 12.1
22 hemopneumothorax 11.4
23 hereditary multiple osteochondromas 11.4
24 endometriosis 10.4
25 pneumonia 10.4
26 pulmonary edema 10.3
27 sarcoma 10.3
28 extracranial arteriovenous malformation 10.3 MMP2 MMP9
29 focal myositis 10.3 MMP2 MMP9
30 villous adenocarcinoma 10.3 MMP2 MMP9
31 lentigo maligna melanoma 10.3 MMP2 MMP9
32 psammomatous meningioma 10.3 MMP2 MMP9
33 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.2 ELN FBN1
34 late-onset focal dermal elastosis 10.2 ELN FBN1
35 acute transverse myelitis 10.2 MMP2 MMP9
36 familial abdominal aortic aneurysm 10.2 ELN FBN1
37 cerebral aneurysms 10.2 ELN MMP2
38 histiocytosis 10.2
39 lung papillary adenocarcinoma 10.2 ALK NFE2L2
40 ischemic colitis 10.2 MMP2 MMP9
41 mid-dermal elastolysis 10.2 ELN FBN1
42 autosomal recessive cutis laxa type iii 10.2 ELN FBN1
43 conjunctival nevus 10.2 MMP2 MMP9
44 breast mucoepidermoid carcinoma 10.2 MUC1 PGR
45 langerhans cell histiocytosis 10.2
46 parotitis 10.2 MMP2 MMP9
47 breast scirrhous carcinoma 10.2 MUC1 PGR
48 endosalpingiosis 10.2 MUC1 PGR
49 pleurisy 10.2
50 klatskin's tumor 10.2 MMP2 MMP9

Graphical network of the top 20 diseases related to Pneumothorax:



Diseases related to Pneumothorax

Symptoms & Phenotypes for Pneumothorax

UMLS symptoms related to Pneumothorax:


dyspnea, hemoptysis

MGI Mouse Phenotypes related to Pneumothorax:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.28 ALK BLVRA FBN1 FLCN FNIP1 FNIP2
2 cellular MP:0005384 10.16 BLVRA FBN1 FLCN FNIP1 FNIP2 MMP9
3 cardiovascular system MP:0005385 10.13 FBN1 FLCN FNIP1 MMP2 MMP9 NFE2L2
4 immune system MP:0005387 10.1 FBN1 FLCN FNIP1 MMP1 MMP2 MMP9
5 mortality/aging MP:0010768 10.1 ALK FBN1 FLCN FNIP1 FNIP2 MMP2
6 integument MP:0010771 9.91 ALK FBN1 MMP9 NFE2L2 PGR SOD1
7 neoplasm MP:0002006 9.9 ALK FLCN FNIP1 FNIP2 MMP1 MMP2
8 muscle MP:0005369 9.8 FBN1 FNIP1 MMP2 MMP9 PGR SOD1
9 renal/urinary system MP:0005367 9.5 FBN1 FLCN FNIP1 FNIP2 MMP9 NFE2L2
10 skeleton MP:0005390 9.23 ALK FBN1 MMP2 MMP9 NFE2L2 PGR

Drugs & Therapeutics for Pneumothorax

Drugs for Pneumothorax (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 253)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 tannic acid Approved Phase 4,Phase 2,Phase 3,Not Applicable
2
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
3
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
4
Desflurane Approved Phase 4 57041-67-5 42113
5
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
6
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
7
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
8
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
9
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
10
Lidocaine Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 137-58-6 3676
11 Poractant alfa Approved Phase 4,Phase 2,Phase 3,Not Applicable 129069-19-8
12
Betamethasone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 378-44-9 9782
13
Mepivacaine Approved, Vet_approved Phase 4,Not Applicable 96-88-8 4062
14
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
15
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
16
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Not Applicable 84057-95-4 175805 71273
17
Hydromorphone Approved, Illicit Phase 4,Not Applicable 466-99-9 5284570
18
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2180-92-9, 38396-39-3 2474
19
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 1177-87-3
20
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-02-2 5743
21
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
22
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 57-27-2 5288826
23
Nitrous oxide Approved, Vet_approved Phase 4,Not Applicable 10024-97-2 948
24
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 51-43-4 5816
25
Racepinephrine Approved Phase 4,Phase 3,Not Applicable 329-65-7 838
26
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
27
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 113775-47-6 68602 5311068
28
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
29
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3 18323-44-9 29029
30
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
31
Remifentanil Approved Phase 4,Phase 1,Phase 2 132875-61-7 60815
32
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
33
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
34
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
35 Pulmonary Surfactants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
38 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Anesthetics, Inhalation Phase 4,Not Applicable
40 Anesthetics, General Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Platelet Aggregation Inhibitors Phase 4,Not Applicable
42 Calamus Phase 4,Phase 2,Phase 3,Not Applicable
43 Neuroprotective Agents Phase 4
44 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Not Applicable
45 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
47 Antiemetics Phase 4,Phase 2,Phase 3,Not Applicable
48 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
50 Hormones Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 593)
# Name Status NCT ID Phase Drugs
1 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
2 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
3 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
4 Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum Unknown status NCT01486953 Phase 4 Desflurane;Sevoflurane
5 Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function Unknown status NCT02509754 Phase 4
6 High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis Unknown status NCT03015051 Phase 4 Oxygen
7 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
8 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
9 Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery Completed NCT01735851 Phase 4 Thoracic epidural analgesia
10 Safety And Accuracy Study Of The Actisight™ Needle Guidance System In Patients Undergoing CT-Guided Procedures Completed NCT01040884 Phase 4
11 Multimodal Analgesic Technique for Control of Post-laproscopy Abdominal Pain Completed NCT03241602 Phase 4 Intraperitoneal lidocaine
12 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Completed NCT00964392 Phase 4
13 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
14 Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants Completed NCT02233985 Phase 4 0.9% Sodium Chloride;3% Sodium Chloride
15 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
16 A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
17 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
18 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
19 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
20 Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Completed NCT01403623 Phase 4
21 ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial Completed NCT00164047 Phase 4 Nitrous Oxide
22 Effect of Dexamethasone Dose and Route on Duration of Interscalene Block After Outpatient Shoulder Surgery Completed NCT02426736 Phase 4 Dexamethasone;Bupivacaine
23 The Retroclavicular Approach for Regional Anesthesia of the Upper Limb in Obese Patients Completed NCT02086643 Phase 4
24 Suprascapular and Axillary Blocks Versus Interscalene Block for Shoulder Surgery Completed NCT02517437 Phase 4 Suprascapular & axillary blocks;Interscalene block
25 OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP Recruiting NCT02140580 Phase 4
26 Is PECS Block Equivalent to Paravertebral Block in Preventing Postoperative Pain After Breast Surgery? Recruiting NCT02645474 Phase 4 Ropivacaine
27 Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU) Recruiting NCT03624881 Phase 4
28 Early Intrapleural TPA Instillation Versus Late Recruiting NCT03167281 Phase 4
29 Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome Recruiting NCT02164734 Phase 4 remifentanil
30 Dexamethasone Dose in Low Volume Bupivacaine USG Supraclavicular Block Recruiting NCT03043495 Phase 4 Dexamethasone
31 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications Active, not recruiting NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
32 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
33 Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery Active, not recruiting NCT03270033 Phase 4 Dexamethasone;Dexmedetomidine
34 Comparative Study Between Single , Intra- Cluster and Double-injection Ultrasound-guided Supraclavicular Block of Brachial Plexus Enrolling by invitation NCT03188939 Phase 4
35 Reactor Thoracostomy Not yet recruiting NCT03769727 Phase 4
36 Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery Not yet recruiting NCT03758261 Phase 4 Paravertebral nerve block;Erector Spinae nerve block
37 Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery Terminated NCT00681174 Phase 4 Morphine;oxycodone;Propofol;Remifentanil;Paracetamol;Morphine
38 Pain Management After Total Shoulder Arthroplasty Terminated NCT03219983 Phase 4 Ropivacaine;liposomal bupivacaine
39 Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma Terminated NCT00557752 Phase 4
40 Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP) Withdrawn NCT00636935 Phase 4 Antibiotics only;Antibiotics + Corticosteroids;Corticosteroids + antibiotics
41 Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax Unknown status NCT01848860 Phase 2, Phase 3
42 Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax Unknown status NCT00418392 Phase 3
43 Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax Unknown status NCT01537289 Phase 3
44 Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Unknown status NCT00713362 Phase 2, Phase 3
45 Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax Unknown status NCT00270751 Phase 2, Phase 3
46 Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax Unknown status NCT00154895 Phase 3 intrapleural minocycline instillation
47 Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure Unknown status NCT01379820 Phase 2, Phase 3
48 Comparing Diagnostic Yield Between R-EBUS Guided Cryo Biopsy Vs. CT Guided Biopsy for PPL Unknown status NCT02395939 Phase 3
49 Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection Unknown status NCT00841750 Phase 3
50 Efficacy and Safety of Sirolimus for Treating Lymphangioleiomyomatosis (LAM) Unknown status NCT00414648 Phase 3 Sirolimus;Placebo sirolimus

Search NIH Clinical Center for Pneumothorax

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: pneumothorax

Genetic Tests for Pneumothorax

Genetic tests related to Pneumothorax:

# Genetic test Affiliating Genes
1 Pneumothorax 29

Anatomical Context for Pneumothorax

MalaCards organs/tissues related to Pneumothorax:

41
Lung, Heart, Testes, Bone, Skin, Kidney, Liver

Publications for Pneumothorax

Articles related to Pneumothorax:

(show top 50) (show all 2521)
# Title Authors Year
1
Spontaneous pneumothorax resulting in tension physiology. ( 30509377 )
2019
2
Pneumothorax following erector spinae plane block. ( 30153535 )
2019
3
Risk of Primary Spontaneous Pneumothorax According to Chest Configuration. ( 29351696 )
2018
4
Thoracic endometriosis syndrome: Comparison between catamenial pneumothorax or endometriosis-related pneumothorax and catamenial hemoptysis. ( 29704815 )
2018
5
Spontaneous pneumothorax: Diagnosis may be a click away. ( 29248325 )
2018
6
Thoracoscopic Blebectomy and Pleurodesis for Primary Spontaneous Pneumothorax. ( 29450816 )
2018
7
Recurrent spontaneous pneumothorax in pregnancy - a case report and review of literature. ( 29915647 )
2018
8
Clinical features of secondary spontaneous pneumothorax complicated with silicosis. ( 29548652 )
2018
9
A total pleural covering of absorbable cellulose mesh prevents pneumothorax recurrence in patients with Birt-Hogg-DubAc syndrome. ( 29764481 )
2018
10
Multidisciplinary team approach on a case of bilateral tension pneumothorax. ( 29850161 )
2018
11
Skin lesions of Birt-Hogg-DubAc syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts. ( 29157599 )
2018
12
Gorlin-Goltz syndrome: first reported case of bullae in the lungs complicated with tension pneumothorax. ( 29930167 )
2018
13
Pneumomediastinum and Pneumothorax Associated with Herpes Simplex Virus (HSV) Pneumonia. ( 29379004 )
2018
14
Management of Suspected Tension Pneumothorax in Tactical Combat Casualty Care: TCCC Guidelines Change 17-02. ( 29889952 )
2018
15
Birt-Hogg-DubAc syndrome: spontaneous pneumothorax as a first symptom. ( 29321196 )
2018
16
A Case of Thoracic Endometriosis Syndrome Presenting with Recurrent Catamenial Pneumothorax. ( 29769481 )
2018
17
Pneumothorax in a preterm during tracheoesophageal fistula repair: Challenges in diagnosis and management. ( 29416484 )
2018
18
OK-432 pleurodesis for the treatment of pneumothorax in patients with interstitial pneumonia. ( 29903606 )
2018
19
Unusual case of primary spontaneous hemopneumothorax in a young man with atypical tension pneumothorax: a case report. ( 29961427 )
2018
20
Incidental finding of large pneumothorax on Cardiac MR scan. ( 29433494 )
2018
21
A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis. ( 29796324 )
2018
22
Chest ultrasonography for the emergency diagnosis of traumatic pneumothorax and haemothorax: A systematic review and meta-analysis. ( 29433802 )
2018
23
Pneumothorax: Laparoscopic Intraoperative Management During Fundoplication Facilitates Management of Cardiopulmonary Instability and Surgical Exposure. ( 29958063 )
2018
24
Pneumothorax: A rare or underreported complication following latissimus dorsi muscle flap. ( 29928092 )
2018
25
Left-sided Catamenial Pneumothorax: A Rare Clinical Entity. ( 29974022 )
2018
26
Discussion: "Evaluation of a novel thoracic entry device versus needle decompression in a tension pneumothorax swine model". ( 29397892 )
2018
27
Pneumothorax secondary to pulmonary alveolar microlithiasis. ( 29636959 )
2018
28
Using Ultrasonography Measurements to Determine the Depth of the GB 21 Acupoint to Prevent Pneumothorax. ( 29936338 )
2018
29
Pneumothorax in a Patient with Unilateral Pulmonary Artery Agenesis. ( 29033433 )
2018
30
Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation. ( 29941192 )
2018
31
Recurrent Spontaneous Pneumothorax as a Manifestation of Birt-Hogg-Dube Syndrome. ( 29397232 )
2018
32
Influence of meteorological factors on the onset of primary spontaneous pneumothorax. ( 29968506 )
2018
33
Pleuroparenchymal fibroelastosis presenting with pneumothorax. ( 29552343 )
2018
34
A pneumothorax? When to look twice and treat once. ( 29374656 )
2018
35
Hormonal manipulation after surgery for catamenial pneumothorax. ( 29049784 )
2018
36
Chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin improved spontaneous pneumothorax and thoracic endometriosis: The first case involving a pregnant woman. ( 29880183 )
2018
37
Contralateral pneumothorax and pneumopericardium after dual-chamber pacemaker implantation: Mechanism, diagnosis, and treatment. ( 29922585 )
2018
38
Chest ultrasonography to assess the kinetics and efficacy of talc pleurodesis in a model of pneumothorax: an experimental animal study. ( 29900179 )
2018
39
An unusual drain in the pleural cavity: iatrogenic pneumothorax due to pulmonary misplacement of a nasogastric tube. ( 29974170 )
2018
40
Bilateral Pneumothorax and Pneumoperitoneum One Year After Thoracoscopic Esophagectomy. ( 29428838 )
2018
41
Pulmonary lymphangioleiomyomatosis presenting as spontaneous pneumothorax treated with sirolimus - A case report. ( 29487252 )
2018
42
A Systematic Review and Meta-Analysis Comparing Pigtail Catheter and Chest Tube as the Initial Treatment for Pneumothorax. ( 29452099 )
2018
43
Childhood pneumothorax in Birt-Hogg-DubAc syndrome: A cohort study and review of the literature. ( 29439288 )
2018
44
Management of primary spontaneous pneumothorax: a review. ( 29974615 )
2018
45
Percutaneous thermal ablation of hepatocellular carcinomas located in the hepatic dome using artificial carbon dioxide pneumothorax: retrospective evaluation of safety and efficacy. ( 29923441 )
2018
46
An unusual presentation of pneumothorax associated with cystic lung metastasis from epithelioid sarcoma: A case report and review of the literature. ( 29541222 )
2018
47
Atmospheric temperature and pressure influence the onset of spontaneous pneumothorax. ( 27666936 )
2018
48
Will the presence of radiological signs of tension pneumothorax affect the clinical presentation of primary spontaneous pneumothorax? ( 29411175 )
2018
49
Computed tomography-guided lung biopsy: Association between biopsy needle angle and pneumothorax development. ( 29435300 )
2018
50
A Rare Cause of Recurrent Spontaneous Pneumothorax: Birt-Hogg-Dube Syndrome. ( 30083407 )
2018

Variations for Pneumothorax

ClinVar genetic disease variations for Pneumothorax:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic GRCh37 Chromosome 9, 137593133: 137593133
2 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic GRCh38 Chromosome 9, 134701287: 134701287

Expression for Pneumothorax

Search GEO for disease gene expression data for Pneumothorax.

Pathways for Pneumothorax

Pathways related to Pneumothorax according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1 12.6 ALK MMP1 MMP2 MMP9 NFE2L2
2
Show member pathways
12.37 ELN FBN1 MMP1 MMP2 MMP9
3
Show member pathways
12.27 FLCN FNIP1 FNIP2 TSC1
4
Show member pathways
12 ELN FBN1 MMP1 MMP2 MMP9
5 11.89 MMP2 MMP9 NFE2L2
6
Show member pathways
11.83 MMP2 MMP9 SOD1
7 11.81 MMP2 MMP9 MUC1
8
Show member pathways
11.7 MMP1 MMP2 MMP9
9 11.51 MMP1 MMP2 MMP9 MUC1
10 11.5 MMP1 MMP2 MMP9
11 11.43 MMP2 MMP9 SOD1
12
Show member pathways
11.38 MMP1 MMP2 MMP9
13 11.33 MMP1 MMP2 MMP9
14 10.96 MMP1 MMP2 MMP9
15 10.95 MMP2 MMP9
16 10.89 MMP1 MMP2
17 10.85 ELN MMP1 MMP9 MUC1
18 10.82 ELN MMP2 MMP9 NFE2L2 SERPINA1
19 10.77 MMP1 MMP9

GO Terms for Pneumothorax

Cellular components related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 ELN FBN1 MMP1 MMP2 MMP9 MUC1
2 collagen-containing extracellular matrix GO:0062023 9.35 ELN FBN1 MMP2 MMP9 SERPINA1
3 extracellular matrix GO:0031012 9.1 ELN FBN1 MMP1 MMP2 MMP9 SOD1

Biological processes related to Pneumothorax according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.8 MMP1 MMP2 MMP9 MUC1
2 cellular protein metabolic process GO:0044267 9.76 FBN1 MMP1 MMP2 SERPINA1
3 positive regulation of protein phosphorylation GO:0001934 9.62 ALK FLCN FNIP1 MMP9
4 extracellular matrix disassembly GO:0022617 9.61 MMP1 MMP2 MMP9
5 regulation of protein phosphorylation GO:0001932 9.58 FLCN FNIP1 FNIP2
6 TOR signaling GO:0031929 9.51 FLCN FNIP1
7 TORC1 signaling GO:0038202 9.48 FNIP1 FNIP2
8 embryo implantation GO:0007566 9.43 MMP2 MMP9 SOD1
9 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.37 MUC1 NFE2L2
10 collagen catabolic process GO:0030574 9.33 MMP1 MMP2 MMP9
11 regulation of pro-B cell differentiation GO:2000973 8.96 FLCN FNIP1
12 negative regulation of TOR signaling GO:0032007 8.8 FLCN FNIP1 TSC1

Molecular functions related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.85 ALK FBN1 MMP9 PGR SERPINA1 SOD1
2 zinc ion binding GO:0008270 9.73 BLVRA MMP1 MMP2 MMP9 PGR SOD1
3 metalloendopeptidase activity GO:0004222 9.58 MMP1 MMP2 MMP9
4 extracellular matrix constituent conferring elasticity GO:0030023 9.32 ELN FBN1
5 chaperone binding GO:0051087 9.26 FNIP1 FNIP2 SOD1 TSC1
6 ATPase inhibitor activity GO:0042030 8.8 FNIP1 FNIP2 TSC1
7 protein binding GO:0005515 10.06 ALK BLVRA ELN FBN1 FLCN FNIP1

Sources for Pneumothorax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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