Aliases & Classifications for Pneumothorax

MalaCards integrated aliases for Pneumothorax:

Name: Pneumothorax 12 76 37 29 55 6 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1673
ICD10 33 J93.1 J93 J93.9
KEGG 37 H01110

Summaries for Pneumothorax

MalaCards based summary : Pneumothorax is related to birt-hogg-dube syndrome and pleural disease, and has symptoms including dyspnea and hemoptysis. An important gene associated with Pneumothorax is FLCN (Folliculin), and among its related pathways/superpathways are Pathways in cancer and Degradation of the extracellular matrix. The drugs Benzocaine and Desflurane have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and kidney, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 76 A pneumothorax is an abnormal collection of air in the pleural space between the lung and the chest... more...

Related Diseases for Pneumothorax

Diseases related to Pneumothorax via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 320)
# Related Disease Score Top Affiliating Genes
1 birt-hogg-dube syndrome 31.9 FLCN FNIP1 FNIP2
2 pleural disease 31.6 FLCN FNIP1 FNIP2
3 marfan syndrome 30.6 ELN FBN1 MMP2
4 epulis 30.1 PGR VIM
5 benign metastasizing leiomyoma 30.0 PGR VIM
6 lymphangioleiomyomatosis 29.9 ELN MMP2 PGR TSC1
7 lung disease 29.8 ELN MMP9 SERPINA1 TSC1
8 pulmonary disease, chronic obstructive 29.7 ELN HMOX1 MMP9 SERPINA1
9 perivascular epithelioid cell tumor 29.6 MUC1 PGR VIM
10 aortic aneurysm, familial thoracic 1 29.6 ELN FBN1 MMP2 MMP9
11 inguinal hernia 29.6 ELN FBN1 MMP2 MMP9
12 pulmonary emphysema 29.6 ELN HMOX1 MMP9 SERPINA1
13 aortic aneurysm 29.5 ELN FBLN5 FBN1
14 fibrosarcoma 29.5 MMP2 MMP9 VIM
15 lung cancer susceptibility 3 29.4 ALK MMP2 MMP9 MUC1 NFE2L2
16 connective tissue disease 29.0 ELN FBLN5 FBN1 MUC1
17 kidney angiomyolipoma 28.6 FLCN FNIP1 TSC1
18 renal cell carcinoma, nonpapillary 28.1 FLCN MMP2 MMP9 MUC1 TSC1 VIM
19 pneumothorax, primary spontaneous 12.7
20 catamenial pneumothorax 12.4
21 tuberculous pneumothorax 12.3
22 spontaneous tension pneumothorax 12.2
23 pulmonary bullae causing pneumothorax 11.9
24 hemopneumothorax 11.2
25 extracranial arteriovenous malformation 10.9 MMP2 MMP9
26 focal myositis 10.9 MMP2 MMP9
27 spastic entropion 10.9 MMP2 MMP9
28 lentigo maligna melanoma 10.9 MMP2 MMP9
29 villous adenocarcinoma 10.9 MMP2 MMP9
30 psammomatous meningioma 10.9 MMP2 MMP9
31 acute transverse myelitis 10.9 MMP2 MMP9
32 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.8 ELN FBN1
33 late-onset focal dermal elastosis 10.8 ELN FBN1
34 familial abdominal aortic aneurysm 10.8 ELN FBN1
35 internal hemorrhoid 10.8 MMP2 MMP9
36 breast mucoepidermoid carcinoma 10.7 MUC1 PGR
37 lung papillary adenocarcinoma 10.7 ALK NFE2L2
38 breast scirrhous carcinoma 10.7 MUC1 PGR
39 gingival hypertrophy 10.7 MMP9 VIM
40 parotitis 10.7 MMP2 MMP9
41 endosalpingiosis 10.7 MUC1 PGR
42 villonodular synovitis 10.7 MMP9 VIM
43 lymphangiomatosis 10.6 PGR VIM
44 clear cell meningioma 10.6 MUC1 PGR
45 adenomyosis 10.6 MMP2 MMP9 PGR
46 light chain deposition disease 10.6 MMP2 MMP9
47 acquired cutis laxa 10.6 ELN FBLN5
48 senile ectropion 10.6 ELN MMP2 MMP9
49 apocrine adenocarcinoma 10.6 MUC1 PGR
50 chronic actinic dermatitis 10.6 ELN FBN1 MMP9

Graphical network of the top 20 diseases related to Pneumothorax:



Diseases related to Pneumothorax

Symptoms & Phenotypes for Pneumothorax

UMLS symptoms related to Pneumothorax:


dyspnea, hemoptysis

MGI Mouse Phenotypes related to Pneumothorax:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.21 NFE2L2 PGR TSC1 MMP9 VIM FLCN
2 homeostasis/metabolism MP:0005376 10.21 PGR TSC1 MMP9 VIM NFE2L2 MMP2
3 cardiovascular system MP:0005385 10.2 NFE2L2 PGR TSC1 MMP9 VIM FLCN
4 mortality/aging MP:0010768 10.1 NFE2L2 PGR TSC1 MMP9 VIM MMP2
5 hematopoietic system MP:0005397 10.06 NFE2L2 PGR MMP9 VIM MMP2 FLCN
6 muscle MP:0005369 9.91 PGR TSC1 MMP9 VIM MMP2 FNIP1
7 neoplasm MP:0002006 9.85 PGR TSC1 NFE2L2 MMP9 FNIP1 ALK
8 renal/urinary system MP:0005367 9.56 NFE2L2 TSC1 MMP9 FLCN FNIP1 FNIP2
9 respiratory system MP:0005388 9.28 NFE2L2 TSC1 MMP9 VIM MMP2 ALK

Drugs & Therapeutics for Pneumothorax

Drugs for Pneumothorax (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 230)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 1994-09-7, 94-09-7 2337
2
Desflurane Approved Phase 4 57041-67-5 42113
3
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
4
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
5
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
7
Lidocaine Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 137-58-6 3676
8 Poractant alfa Approved Phase 4,Phase 2,Phase 3,Not Applicable 129069-19-8
9
Betamethasone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 378-44-9 9782
10
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
11
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
12
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
13
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
14
Hydromorphone Approved, Illicit Phase 4,Not Applicable 466-99-9 5284570
15
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 71273 175805
16
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
17
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
18
Morphine Approved, Investigational Phase 4,Phase 2,Not Applicable 57-27-2 5288826
19
Nitrous oxide Approved, Vet_approved Phase 4,Not Applicable 10024-97-2 948
20
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
21
Mepivacaine Approved, Vet_approved Phase 4,Not Applicable 96-88-8 4062
22
Racepinephrine Approved Phase 4 329-65-7 838
23
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
24
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 113775-47-6 68602 5311068
25
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
26
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3 18323-44-9 29029
27
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
28
Remifentanil Approved Phase 4,Phase 1,Phase 2 132875-61-7 60815
29
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
30
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
31 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
32 Pulmonary Surfactants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
33 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Anesthetics, General Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
36 Anesthetics, Inhalation Phase 4,Not Applicable
37 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Platelet Aggregation Inhibitors Phase 4,Not Applicable
39 Antiemetics Phase 4,Phase 2,Phase 3
40 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
41 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
42 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
43 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
44 glucocorticoids Phase 4,Phase 3,Phase 2
45 Hormone Antagonists Phase 4,Phase 3,Phase 2
46 Hormones Phase 4,Phase 3,Phase 2
47 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
48 Methylprednisolone acetate Phase 4
49 Methylprednisolone Hemisuccinate Phase 4
50 Neuroprotective Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 537)
# Name Status NCT ID Phase Drugs
1 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
2 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
3 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
4 Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum Unknown status NCT01486953 Phase 4 Desflurane;Sevoflurane
5 Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function Unknown status NCT02509754 Phase 4
6 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
7 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
8 Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery Completed NCT01735851 Phase 4 Thoracic epidural analgesia
9 Safety And Accuracy Study Of The Actisight™ Needle Guidance System In Patients Undergoing CT-Guided Procedures Completed NCT01040884 Phase 4
10 Multimodal Analgesic Technique for Control of Post-laproscopy Abdominal Pain Completed NCT03241602 Phase 4 Intraperitoneal lidocaine
11 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
12 Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants Completed NCT02233985 Phase 4 0.9% Sodium Chloride;3% Sodium Chloride
13 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
14 A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
15 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
16 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
17 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
18 Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Completed NCT01403623 Phase 4
19 ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial Completed NCT00164047 Phase 4 Nitrous Oxide
20 Effect of Dexamethasone Dose and Route on Duration of Interscalene Block After Outpatient Shoulder Surgery Completed NCT02426736 Phase 4 Dexamethasone;Bupivacaine
21 The Retroclavicular Approach for Regional Anesthesia of the Upper Limb in Obese Patients Completed NCT02086643 Phase 4
22 Suprascapular and Axillary Blocks Versus Interscalene Block for Shoulder Surgery Completed NCT02517437 Phase 4 Suprascapular & axillary blocks;Interscalene block
23 OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP Recruiting NCT02140580 Phase 4
24 Is PECS Block Equivalent to Paravertebral Block in Preventing Postoperative Pain After Breast Surgery? Recruiting NCT02645474 Phase 4 Ropivacaine
25 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications Recruiting NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
26 High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis Recruiting NCT03015051 Phase 4 Oxygen
27 Early Intrapleural TPA Instillation Versus Late Recruiting NCT03167281 Phase 4
28 Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome Recruiting NCT02164734 Phase 4 remifentanil
29 Dexamethasone Dose in Low Volume Bupivacaine USG Supraclavicular Block Recruiting NCT03043495 Phase 4 Dexamethasone
30 Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery Recruiting NCT03270033 Phase 4 Dexamethasone;Dexmedetomidine
31 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
32 NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Active, not recruiting NCT00964392 Phase 4
33 Comparative Study Between Single , Intra- Cluster and Double-injection Ultrasound-guided Supraclavicular Block of Brachial Plexus Enrolling by invitation NCT03188939 Phase 4
34 Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery Terminated NCT00681174 Phase 4 Morphine;oxycodone;Propofol;Remifentanil;Paracetamol;Morphine
35 Pain Management After Total Shoulder Arthroplasty Terminated NCT03219983 Phase 4 Ropivacaine;liposomal bupivacaine
36 Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma Terminated NCT00557752 Phase 4
37 Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP) Withdrawn NCT00636935 Phase 4 Antibiotics only;Antibiotics + Corticosteroids;Corticosteroids + antibiotics
38 Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax Unknown status NCT00418392 Phase 3
39 Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax Unknown status NCT01537289 Phase 3
40 Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Unknown status NCT00713362 Phase 2, Phase 3
41 Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax Unknown status NCT00270751 Phase 2, Phase 3
42 Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax Unknown status NCT00154895 Phase 3 intrapleural minocycline instillation
43 Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure Unknown status NCT01379820 Phase 2, Phase 3
44 Comparing Diagnostic Yield Between R-EBUS Guided Cryo Biopsy Vs. CT Guided Biopsy for PPL Unknown status NCT02395939 Phase 3
45 Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection Unknown status NCT00841750 Phase 3
46 Efficacy and Safety of Sirolimus for Treating Lymphangioleiomyomatosis (LAM) Unknown status NCT00414648 Phase 3 Sirolimus;Placebo sirolimus
47 Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration Unknown status NCT00312507 Phase 3 Bovine Lipid Extract Surfactant (administered by lavage);Bovine Lipid Extract Surfactant (administered by bolus)
48 Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure Completed NCT00562302 Phase 3
49 Efficacy of the Additional Mechanical Pleurodesis for Surgical Management of Primary Spontaneous Pneumothorax Completed NCT00615849 Phase 3
50 Evaluation of the Bio-Seal Biopsy Track Plug Completed NCT00527722 Phase 2, Phase 3

Search NIH Clinical Center for Pneumothorax

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Pneumothorax

Genetic tests related to Pneumothorax:

# Genetic test Affiliating Genes
1 Pneumothorax 29

Anatomical Context for Pneumothorax

MalaCards organs/tissues related to Pneumothorax:

41
Lung, Heart, Kidney, Liver, Brain, Testes, Skin

Publications for Pneumothorax

Articles related to Pneumothorax:

(show top 50) (show all 1634)
# Title Authors Year
1
Risk of Primary Spontaneous Pneumothorax According to Chest Configuration. ( 29351696 )
2018
2
Thoracic endometriosis syndrome: Comparison between catamenial pneumothorax or endometriosis-related pneumothorax and catamenial hemoptysis. ( 29704815 )
2018
3
Spontaneous pneumothorax: Diagnosis may be a click away. ( 29248325 )
2018
4
Thoracoscopic Blebectomy and Pleurodesis for Primary Spontaneous Pneumothorax. ( 29450816 )
2018
5
Recurrent spontaneous pneumothorax in pregnancy - a case report and review of literature. ( 29915647 )
2018
6
Clinical features of secondary spontaneous pneumothorax complicated with silicosis. ( 29548652 )
2018
7
A total pleural covering of absorbable cellulose mesh prevents pneumothorax recurrence in patients with Birt-Hogg-DubAc syndrome. ( 29764481 )
2018
8
Multidisciplinary team approach on a case of bilateral tension pneumothorax. ( 29850161 )
2018
9
Skin lesions of Birt-Hogg-DubAc syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts. ( 29157599 )
2018
10
Gorlin-Goltz syndrome: first reported case of bullae in the lungs complicated with tension pneumothorax. ( 29930167 )
2018
11
Pneumomediastinum and Pneumothorax Associated with Herpes Simplex Virus (HSV) Pneumonia. ( 29379004 )
2018
12
Management of Suspected Tension Pneumothorax in Tactical Combat Casualty Care: TCCC Guidelines Change 17-02. ( 29889952 )
2018
13
Birt-Hogg-DubAc syndrome: spontaneous pneumothorax as a first symptom. ( 29321196 )
2018
14
A Case of Thoracic Endometriosis Syndrome Presenting with Recurrent Catamenial Pneumothorax. ( 29769481 )
2018
15
Pneumothorax in a preterm during tracheoesophageal fistula repair: Challenges in diagnosis and management. ( 29416484 )
2018
16
OK-432 pleurodesis for the treatment of pneumothorax in patients with interstitial pneumonia. ( 29903606 )
2018
17
Unusual case of primary spontaneous hemopneumothorax in a young man with atypical tension pneumothorax: a case report. ( 29961427 )
2018
18
Incidental finding of large pneumothorax on Cardiac MR scan. ( 29433494 )
2018
19
A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis. ( 29796324 )
2018
20
Chest ultrasonography for the emergency diagnosis of traumatic pneumothorax and haemothorax: A systematic review and meta-analysis. ( 29433802 )
2018
21
Pneumothorax: Laparoscopic Intraoperative Management During Fundoplication Facilitates Management of Cardiopulmonary Instability and Surgical Exposure. ( 29958063 )
2018
22
Pneumothorax: A rare or underreported complication following latissimus dorsi muscle flap. ( 29928092 )
2018
23
Left-sided Catamenial Pneumothorax: A Rare Clinical Entity. ( 29974022 )
2018
24
Discussion: "Evaluation of a novel thoracic entry device versus needle decompression in a tension pneumothorax swine model". ( 29397892 )
2018
25
Pneumothorax secondary to pulmonary alveolar microlithiasis. ( 29636959 )
2018
26
Using Ultrasonography Measurements to Determine the Depth of the GB 21 Acupoint to Prevent Pneumothorax. ( 29936338 )
2018
27
Pneumothorax in a Patient with Unilateral Pulmonary Artery Agenesis. ( 29033433 )
2018
28
Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation. ( 29941192 )
2018
29
Recurrent Spontaneous Pneumothorax as a Manifestation of Birt-Hogg-Dube Syndrome. ( 29397232 )
2018
30
Influence of meteorological factors on the onset of primary spontaneous pneumothorax. ( 29968506 )
2018
31
Pleuroparenchymal fibroelastosis presenting with pneumothorax. ( 29552343 )
2018
32
A pneumothorax? When to look twice and treat once. ( 29374656 )
2018
33
Hormonal manipulation after surgery for catamenial pneumothorax. ( 29049784 )
2018
34
Chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin improved spontaneous pneumothorax and thoracic endometriosis: The first case involving a pregnant woman. ( 29880183 )
2018
35
Contralateral pneumothorax and pneumopericardium after dual-chamber pacemaker implantation: Mechanism, diagnosis, and treatment. ( 29922585 )
2018
36
Chest ultrasonography to assess the kinetics and efficacy of talc pleurodesis in a model of pneumothorax: an experimental animal study. ( 29900179 )
2018
37
An unusual drain in the pleural cavity: iatrogenic pneumothorax due to pulmonary misplacement of a nasogastric tube. ( 29974170 )
2018
38
Bilateral Pneumothorax and Pneumoperitoneum One Year After Thoracoscopic Esophagectomy. ( 29428838 )
2018
39
Pulmonary lymphangioleiomyomatosis presenting as spontaneous pneumothorax treated with sirolimus - A case report. ( 29487252 )
2018
40
A Systematic Review and Meta-Analysis Comparing Pigtail Catheter and Chest Tube as the Initial Treatment for Pneumothorax. ( 29452099 )
2018
41
Childhood pneumothorax in Birt-Hogg-DubAc syndrome: A cohort study and review of the literature. ( 29439288 )
2018
42
Management of primary spontaneous pneumothorax: a review. ( 29974615 )
2018
43
Percutaneous thermal ablation of hepatocellular carcinomas located in the hepatic dome using artificial carbon dioxide pneumothorax: retrospective evaluation of safety and efficacy. ( 29923441 )
2018
44
An unusual presentation of pneumothorax associated with cystic lung metastasis from epithelioid sarcoma: A case report and review of the literature. ( 29541222 )
2018
45
Atmospheric temperature and pressure influence the onset of spontaneous pneumothorax. ( 27666936 )
2018
46
Will the presence of radiological signs of tension pneumothorax affect the clinical presentation of primary spontaneous pneumothorax? ( 29411175 )
2018
47
Computed tomography-guided lung biopsy: Association between biopsy needle angle and pneumothorax development. ( 29435300 )
2018
48
Catamenial pneumothorax caused by thoracic endometriosis. ( 29552245 )
2018
49
A Case Report of Secondary Simultaneous Bilateral Pneumothorax Due to Pazopanib Treatment. ( 29404187 )
2018
50
Massive intraperitoneal free air induced by pneumothorax and pneumomediastinum. ( 29966954 )
2018

Variations for Pneumothorax

ClinVar genetic disease variations for Pneumothorax:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 46;XY;t(20;22)(q13.3;q11.2) Translocation Uncertain significance
2 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic GRCh37 Chromosome 9, 137593133: 137593133
3 COL5A1 NM_000093.4(COL5A1): c.608G> T (p.Gly203Val) single nucleotide variant Likely pathogenic GRCh38 Chromosome 9, 134701287: 134701287

Expression for Pneumothorax

Search GEO for disease gene expression data for Pneumothorax.

Pathways for Pneumothorax

GO Terms for Pneumothorax

Cellular components related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 FBLN5 FBN1 HMOX1 MMP2 MMP9 MUC1
2 extracellular matrix GO:0031012 9.02 ELN FBLN5 FBN1 MMP2 MMP9
3 elastic fiber GO:0071953 8.96 ELN FBLN5

Biological processes related to Pneumothorax according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.71 ELN FBLN5 FBN1 MMP9
2 cytokine-mediated signaling pathway GO:0019221 9.55 HMOX1 MMP2 MMP9 MUC1 VIM
3 regulation of protein phosphorylation GO:0001932 9.54 FLCN FNIP1 FNIP2
4 TOR signaling GO:0031929 9.49 FLCN FNIP1
5 negative regulation of macroautophagy GO:0016242 9.48 HMOX1 TSC1
6 heme catabolic process GO:0042167 9.46 BLVRA HMOX1
7 regulation of removal of superoxide radicals GO:2000121 9.43 FBLN5 NFE2L2
8 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.32 MUC1 NFE2L2
9 regulation of pro-B cell differentiation GO:2000973 9.26 FLCN FNIP1
10 negative regulation of TOR signaling GO:0032007 9.13 FLCN FNIP1 TSC1
11 extracellular matrix disassembly GO:0022617 8.92 ELN FBN1 MMP2 MMP9

Molecular functions related to Pneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.89 ALK BLVRA ELN FBLN5 FBN1 FLCN
2 identical protein binding GO:0042802 9.73 ALK FBN1 MMP9 PGR SERPINA1 VIM
3 chaperone binding GO:0051087 9.33 FNIP1 FNIP2 TSC1
4 ATPase inhibitor activity GO:0042030 8.8 FNIP1 FNIP2 TSC1

Sources for Pneumothorax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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45 MESH via Orphanet
46 MGI
49 NCI
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51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
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74 UMLS via Orphanet
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