MCID: PLY003
MIFTS: 25

Polycystic Echinococcosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Polycystic Echinococcosis

MalaCards integrated aliases for Polycystic Echinococcosis:

Name: Polycystic Echinococcosis 12 15
Human Polycystic Hydatid Disease 12
Neotropical Echinococcosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050218

Summaries for Polycystic Echinococcosis

Disease Ontology : 12 An echinococcosis that is caused by the larvae of Echinococcus vogeli or Echinococcus oligarthrus, which infect the liver.

MalaCards based summary : Polycystic Echinococcosis, also known as human polycystic hydatid disease, is related to echinococcosis and cystic echinococcosis. An important gene associated with Polycystic Echinococcosis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are CXCR3-mediated signaling events and Phase I biotransformations, non P450. Affiliated tissues include heart, skin and cervix.

Related Diseases for Polycystic Echinococcosis

Diseases related to Polycystic Echinococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 echinococcosis 31.7 MT-ND1 MT-CO1 CES2 CES1
2 cystic echinococcosis 30.1 MT-ND1 MT-CO1 CES2 CES1
3 alveolar echinococcosis 30.0 MT-CO1 CES2 CES1
4 diphyllobothriasis 10.3 MT-ND1 MT-CO1
5 coenurosis 10.3 MT-ND1 MT-CO1
6 sparganosis 10.3 MT-ND1 MT-CO1
7 myiasis 10.3 MT-ND1 MT-CO1
8 large intestine adenoma 10.3 CES2 CES1
9 thelaziasis 10.2 MT-ND1 MT-CO1
10 baylisascariasis 10.2 MT-ND1 MT-CO1
11 mitochondrial myopathy, infantile, transient 10.2 MT-ND1 MT-CO1
12 deafness, nonsyndromic sensorineural, mitochondrial 10.2 MT-ND1 MT-CO1
13 pthirus pubis infestation 10.2 MT-ND1 MT-CO1
14 lice infestation 10.2 MT-ND1 MT-CO1
15 hereditary optic neuropathy 10.2 MT-ND1 MT-CO1
16 pediculus humanus corporis infestation 10.2 MT-CO1 CXCL11
17 fascioliasis 10.2 MT-ND1 MT-CO1
18 hemophagocytic lymphohistiocytosis, familial, 3 10.2 CES2 CES1
19 parasitic ectoparasitic infectious disease 10.2 MT-ND1 MT-CO1
20 deafness, aminoglycoside-induced 10.1 MT-ND1 MT-CO1
21 cysticercosis 10.1 MT-ND1 MT-CO1 CES2
22 endotheliitis 10.0 CXCL11 CXCL10
23 opsoclonus-myoclonus syndrome 10.0 CXCL11 CXCL10
24 yemenite deaf-blind hypopigmentation syndrome 10.0
25 ptosis 10.0
26 ebola hemorrhagic fever 10.0 F3 CXCL10
27 hantavirus hemorrhagic fever with renal syndrome 10.0 F3 CXCL10
28 cortical blindness 10.0 MT-ND1 F3
29 crimean-congo hemorrhagic fever 9.9 F3 CXCL10
30 vagus nerve disease 9.9 ATP4A ATP12A
31 necrotizing gastritis 9.9 ATP4A ATP12A
32 scalp dermatosis 9.9 ATP4A ATP12A
33 hemangioma of intra-abdominal structure 9.9 ATP4A ATP12A
34 acquired gastric outlet stenosis 9.9 ATP4A ATP12A
35 lingual goiter 9.9 ATP4A ATP12A
36 displacement of cardia through esophageal hiatus 9.9 ATP4A ATP12A
37 bacterial esophagitis 9.9 ATP4A ATP12A
38 cascade stomach 9.9 ATP4A ATP12A
39 benzylpenicillin allergy 9.9 ATP4A ATP12A
40 median arcuate ligament syndrome 9.9 ATP4A ATP12A
41 afferent loop syndrome 9.9 ATP4A ATP12A
42 cervix erosion 9.9 ATP4A ATP12A
43 angiodysplasia of intestine 9.9 ATP4A ATP12A
44 granulomatous gastritis 9.9 ATP4A ATP12A
45 laryngeal tuberculosis 9.9 ATP4A ATP12A
46 fungal esophagitis 9.9 ATP4A ATP12A
47 dieulafoy lesion 9.9 ATP4A ATP12A
48 esophagus melanoma 9.9 ATP4A ATP12A
49 cefuroxime allergy 9.9 ATP4A ATP12A
50 gastric gastrinoma 9.9 ATP4A ATP12A

Graphical network of the top 20 diseases related to Polycystic Echinococcosis:



Diseases related to Polycystic Echinococcosis

Symptoms & Phenotypes for Polycystic Echinococcosis

Drugs & Therapeutics for Polycystic Echinococcosis

Search Clinical Trials , NIH Clinical Center for Polycystic Echinococcosis

Genetic Tests for Polycystic Echinococcosis

Anatomical Context for Polycystic Echinococcosis

MalaCards organs/tissues related to Polycystic Echinococcosis:

40
Heart, Skin, Cervix, Liver

Publications for Polycystic Echinococcosis

Articles related to Polycystic Echinococcosis:

(show all 39)
# Title Authors PMID Year
1
Radical resection of hepatic polycystic echinococcosis complicated with hepatocellular carcinoma: A case report. 61
33553405 2021
2
International consensus on terminology to be used in the field of echinococcoses. 61
32500855 2020
3
Review on Epidemiology and Public Health Significance of Hydatidosis. 61
33354312 2020
4
Intense Pericardial Involvement in Polycystic Echinococcosis Submitted to Successful Medical Treatment. 61
31813272 2019
5
Revisiting the Phylogenetic History of Helminths Through Genomics, the Case of the New Echinococcus oligarthrus Genome. 61
31440275 2019
6
Genetic diversity of Echinococcus vogeli in the western Brazilian Amazon. 61
31576902 2019
7
First parasitological, histopathological and molecular characterization of Echinococcus vogeli Rausch and Bernstein, 1972 from Cuniculus paca Linnaeus, 1766 in the Cerrado biome (Mato Grosso do Sul, Brazil). 61
29329621 2018
8
Echinococcus oligarthrus in the subtropical region of Argentina: First integration of morphological and molecular analyses determines two distinct populations. 61
28433410 2017
9
Neotropical echinococcosis caused by Echinococcus vogeli in a 6-year-old child: the second case report in humans in French Guiana. 61
26355940 2017
10
The Echinococcoses: Diagnosis, Clinical Management and Burden of Disease. 61
28212790 2017
11
First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil. 61
28088247 2017
12
Morphometric characteristics of the metacestode Echinococcus vogeli Rausch & Bernstein, 1972 in human infections from the northern region of Brazil. 61
24849308 2015
13
Polycystic echinococcosis in Pacas, Amazon region, Peru. 61
25695937 2015
14
Neotropical echinococcosis: second report of Echinococcus vogeli natural infection in its main definitive host, the bush dog (Speothos venaticus). 61
24148288 2014
15
Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France. 61
25058754 2014
16
Histopathological findings of an uncommon co-infection: Echinococcus vogeli, HIV, hepatitis C virus, and hepatitis B virus. 61
23735863 2013
17
Molecular diagnosis of polycystic echinococcosis due to Echinococcus vogeli in a Paraguayan immigrant in Argentina. 61
23824768 2013
18
Polycystic echinococcosis in the state of Acre, Brazil: contribution to patient diagnosis, treatment and prognosis. 61
23903966 2013
19
[First report of Echinococcus vogeli in a paca in Misiones province, Argentina]. 61
24165140 2013
20
Liver transplantation for neotropical polycystic echinococcosis caused by Echinococcus vogeli: a case report. 61
23563842 2013
21
Anatomo-clinical and molecular description of liver neotropical echinococcosis caused by Echinococcus oligarthrus in human host. 61
23010160 2013
22
Polycystic echinococcosis. 61
20363373 2010
23
Atypical polycystic echinococcosis without liver involvement in Brazilian patients. 61
19786288 2010
24
Serological reactivity of patients with Echinococcus infections (E. granulosus, E. vogeli, and E. multilocularis) against three antigen B subunits. 61
20066435 2010
25
New aspects of neotropical polycystic (Echinococcus vogeli) and unicystic (Echinococcus oligarthrus) echinococcosis. 61
18400802 2008
26
Emergence of polycystic neotropical echinococcosis. 61
18258123 2008
27
Successful outcome of hepatic polycystic echinococcosis managed with surgery and chemotherapy. 61
17014876 2007
28
Polycystic echinococcosis of the orbit. 61
16139021 2005
29
First report of a human case of polycystic echinococcosis due to Echinococcus vogeli from neotropical area of Peru, South America. 61
15057334 2004
30
[Polycystic echinococcosis in the Eastern Brazilian Amazon: an update]. 61
15586901 2004
31
Pulmonary echinococcosis. 61
12797504 2003
32
An autochthonous case of Echinococcus vogeli Rausch & Bernstein, 1972 polycystic echinococcosis in the state of Rondônia, Brazil. 61
11992162 2002
33
The occurrence of polycystic echinococcosis in Suriname. 61
10884869 2000
34
Neotropical echinococcosis in Suriname: Echinococcus oligarthrus in the orbit and Echinococcus vogeli in the abdomen. 61
9840599 1998
35
Images in hepatology. Polycystic echinococcosis by E. vogeli in the Amazon region. 61
9625327 1998
36
Polycystic echinococcosis in tropical America: Echinococcus vogeli and E. oligarthrus. 61
9236939 1997
37
Immunodiagnosis of polycystic hydatid disease/polycystic echinococcosis due to Echinococcus vogeli. 61
7485718 1995
38
Polycystic echinococcosis in Colombia: the larval cestodes in infected rodents. 61
501848 1979
39
Neotropical echinococcosis in Columbia. 61
5039097 1972

Variations for Polycystic Echinococcosis

Expression for Polycystic Echinococcosis

Search GEO for disease gene expression data for Polycystic Echinococcosis.

Pathways for Polycystic Echinococcosis

Pathways related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.49 CXCL11 CXCL10
2 9.53 CES2 CES1

GO Terms for Polycystic Echinococcosis

Cellular components related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 F3 CXCL11 CXCL10 CES2 CES1 ATP4A

Biological processes related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.46 ATP4A ATP12A
2 aerobic respiration GO:0009060 9.43 MT-ND1 MT-CO1
3 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.4 CXCL11 CXCL10
4 cellular sodium ion homeostasis GO:0006883 9.37 ATP4A ATP12A
5 proton transmembrane transport GO:1902600 9.33 MT-CO1 ATP4A ATP12A
6 sodium ion export across plasma membrane GO:0036376 9.32 ATP4A ATP12A
7 cellular potassium ion homeostasis GO:0030007 9.26 ATP4A ATP12A
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.96 ATP4A ATP12A
9 T cell chemotaxis GO:0010818 8.62 CXCL11 CXCL10

Molecular functions related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carboxylic ester hydrolase activity GO:0052689 9.48 CES2 CES1
2 triglyceride lipase activity GO:0004806 9.46 CES2 CES1
3 CXCR chemokine receptor binding GO:0045236 9.43 CXCL11 CXCL10
4 sodium:potassium-exchanging ATPase activity GO:0005391 9.4 ATP4A ATP12A
5 sterol esterase activity GO:0004771 9.37 CES2 CES1
6 potassium-transporting ATPase activity GO:0008556 9.32 ATP4A ATP12A
7 CXCR3 chemokine receptor binding GO:0048248 9.26 CXCL11 CXCL10
8 methyl indole-3-acetate esterase activity GO:0080030 9.16 CES2 CES1
9 methylumbelliferyl-acetate deacetylase activity GO:0047374 8.96 CES2 CES1
10 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Polycystic Echinococcosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....