MCID: PLY003
MIFTS: 24

Polycystic Echinococcosis

Categories: Endocrine diseases, Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Polycystic Echinococcosis

MalaCards integrated aliases for Polycystic Echinococcosis:

Name: Polycystic Echinococcosis 12 15
Human Polycystic Hydatid Disease 12
Neotropical Echinococcosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050218

Summaries for Polycystic Echinococcosis

Disease Ontology : 12 An echinococcosis that is caused by the larvae of Echinococcus vogeli or Echinococcus oligarthrus, which infect the liver.

MalaCards based summary : Polycystic Echinococcosis, also known as human polycystic hydatid disease, is related to echinococcosis and alveolar echinococcosis. An important gene associated with Polycystic Echinococcosis is PTF1A (Pancreas Associated Transcription Factor 1a), and among its related pathways/superpathways is Phase I biotransformations, non P450. Affiliated tissues include liver and testes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Polycystic Echinococcosis

Graphical network of the top 20 diseases related to Polycystic Echinococcosis:



Diseases related to Polycystic Echinococcosis

Symptoms & Phenotypes for Polycystic Echinococcosis

GenomeRNAi Phenotypes related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

26 (show all 21)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-108 9.68 CXCL11 RRAGB YBX1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.68 CXCL11
3 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.68 CXCL11
4 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.68 YBX1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.68 YBX1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.68 CXCL11
7 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.68 YBX1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.68 YBX1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.68 CXCL11
10 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.68 RRAGB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.68 RRAGB
12 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.68 RRAGB
13 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.68 RRAGB
14 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.68 YBX1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.68 RRAGB
16 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.68 CXCL11
17 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.68 RRAGB
18 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.68 RRAGB
19 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.68 YBX1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.68 YBX1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.68 RRAGB

MGI Mouse Phenotypes related to Polycystic Echinococcosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.44 CES1 CHKA CIART CLU F3 FLNA

Drugs & Therapeutics for Polycystic Echinococcosis

Search Clinical Trials , NIH Clinical Center for Polycystic Echinococcosis

Genetic Tests for Polycystic Echinococcosis

Anatomical Context for Polycystic Echinococcosis

MalaCards organs/tissues related to Polycystic Echinococcosis:

40
Liver, Testes

Publications for Polycystic Echinococcosis

Articles related to Polycystic Echinococcosis:

(show all 36)
# Title Authors PMID Year
1
Intense Pericardial Involvement in Polycystic Echinococcosis Submitted to Successful Medical Treatment. 61
31813272 2019
2
Genetic diversity of Echinococcus vogeli in the western Brazilian Amazon. 61
31576902 2019
3
Revisiting the Phylogenetic History of Helminths Through Genomics, the Case of the New Echinococcus oligarthrus Genome. 61
31440275 2019
4
First parasitological, histopathological and molecular characterization of Echinococcus vogeli Rausch and Bernstein, 1972 from Cuniculus paca Linnaeus, 1766 in the Cerrado biome (Mato Grosso do Sul, Brazil). 61
29329621 2018
5
Echinococcus oligarthrus in the subtropical region of Argentina: First integration of morphological and molecular analyses determines two distinct populations. 61
28433410 2017
6
Neotropical echinococcosis caused by Echinococcus vogeli in a 6-year-old child: the second case report in humans in French Guiana. 61
26355940 2017
7
First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil. 61
28088247 2017
8
The Echinococcoses: Diagnosis, Clinical Management and Burden of Disease. 61
28212790 2017
9
Morphometric characteristics of the metacestode Echinococcus vogeli Rausch & Bernstein, 1972 in human infections from the northern region of Brazil. 61
24849308 2015
10
Polycystic echinococcosis in Pacas, Amazon region, Peru. 61
25695937 2015
11
Neotropical echinococcosis: second report of Echinococcus vogeli natural infection in its main definitive host, the bush dog (Speothos venaticus). 61
24148288 2014
12
Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France. 61
25058754 2014
13
Histopathological findings of an uncommon co-infection: Echinococcus vogeli, HIV, hepatitis C virus, and hepatitis B virus. 61
23735863 2013
14
Molecular diagnosis of polycystic echinococcosis due to Echinococcus vogeli in a Paraguayan immigrant in Argentina. 61
23824768 2013
15
Polycystic echinococcosis in the state of Acre, Brazil: contribution to patient diagnosis, treatment and prognosis. 61
23903966 2013
16
[First report of Echinococcus vogeli in a paca in Misiones province, Argentina]. 61
24165140 2013
17
Anatomo-clinical and molecular description of liver neotropical echinococcosis caused by Echinococcus oligarthrus in human host. 61
23010160 2013
18
Liver transplantation for neotropical polycystic echinococcosis caused by Echinococcus vogeli: a case report. 61
23563842 2013
19
Polycystic echinococcosis. 61
20363373 2010
20
Atypical polycystic echinococcosis without liver involvement in Brazilian patients. 61
19786288 2010
21
Serological reactivity of patients with Echinococcus infections (E. granulosus, E. vogeli, and E. multilocularis) against three antigen B subunits. 61
20066435 2010
22
New aspects of neotropical polycystic (Echinococcus vogeli) and unicystic (Echinococcus oligarthrus) echinococcosis. 61
18400802 2008
23
Emergence of polycystic neotropical echinococcosis. 61
18258123 2008
24
Successful outcome of hepatic polycystic echinococcosis managed with surgery and chemotherapy. 61
17014876 2007
25
Polycystic echinococcosis of the orbit. 61
16139021 2005
26
[Polycystic echinococcosis in the Eastern Brazilian Amazon: an update]. 61
15586901 2004
27
First report of a human case of polycystic echinococcosis due to Echinococcus vogeli from neotropical area of Peru, South America. 61
15057334 2004
28
Pulmonary echinococcosis. 61
12797504 2003
29
An autochthonous case of Echinococcus vogeli Rausch & Bernstein, 1972 polycystic echinococcosis in the state of Rondônia, Brazil. 61
11992162 2002
30
The occurrence of polycystic echinococcosis in Suriname. 61
10884869 2000
31
Neotropical echinococcosis in Suriname: Echinococcus oligarthrus in the orbit and Echinococcus vogeli in the abdomen. 61
9840599 1998
32
Images in hepatology. Polycystic echinococcosis by E. vogeli in the Amazon region. 61
9625327 1998
33
Polycystic echinococcosis in tropical America: Echinococcus vogeli and E. oligarthrus. 61
9236939 1997
34
Immunodiagnosis of polycystic hydatid disease/polycystic echinococcosis due to Echinococcus vogeli. 61
7485718 1995
35
Polycystic echinococcosis in Colombia: the larval cestodes in infected rodents. 61
501848 1979
36
Neotropical echinococcosis in Columbia. 61
5039097 1972

Variations for Polycystic Echinococcosis

Expression for Polycystic Echinococcosis

Search GEO for disease gene expression data for Polycystic Echinococcosis.

Pathways for Polycystic Echinococcosis

Pathways related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.53 CES2 CES1

GO Terms for Polycystic Echinococcosis

Cellular components related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 TACSTD2 MIF LGALS3BP F3 CXCL11 CLU
2 apical dendrite GO:0097440 8.96 FLNA CLU

Biological processes related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.8 LGALS3BP FLNA CLU

Molecular functions related to Polycystic Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 methyl indole-3-acetate esterase activity GO:0080030 9.16 CES2 CES1
2 GTPase binding GO:0051020 9.13 YBX1 RRAGB FLNA
3 methylumbelliferyl-acetate deacetylase activity GO:0047374 8.62 CES2 CES1

Sources for Polycystic Echinococcosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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